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Optic coherence tomography optic nerve head in children

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https://www.readbyqxmd.com/read/29719642/oct-based-macular-thickness-in-a-normal-indian-pediatric-population
#1
Bharti Nigam, Pragati Garg, Lubna Ahmad, Ritika Mullick
Purpose: Cirrus optical coherence tomography (OCT) provides high resolution cross-sectional images of the retina, vitreous humor, and optic nerve head with an axial resolution of 5 μm and a reproducibility of 1.6 μm. An integrated normative database is available only for adult subjects ≥18 years of age; the normal reference ranges of the macular thicknesses of pediatric subjects are not available. The purpose of this study was to determine the normal reference range of macular thickness of pediatric...
April 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29659172/optic-disc-drusen-understanding-an-old-problem-from-a-new-perspective
#2
REVIEW
Steffen Hamann, Lasse Malmqvist, Fiona Costello
Optic disc drusen (ODD) are acellular deposits located in the optic nerve head of up to 2.4% of the population. They may develop as by-products of impaired axonal metabolism in genetically predisposed individuals, in whom a narrow scleral canal is hypothesized to play a role. Although ODD are often considered as benign innocent bystanders, recognized as part of a routine ophthalmological examination, the vast majority of patients with ODD have visual field defects. Optic disc drusen (ODD)-associated complications with severe visual loss, most often due to anterior ischaemic optic neuropathy, are also known to occur...
April 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29563952/optic-nerve-head-parameters-measured-with-spectral-domain-optical-coherence-tomography-in-healthy-turkish-children-normal-values-repeatability-and-interocular-symmetry
#3
Ozge Yabas Kiziloglu, Okan Toygar, Baha Toygar, Ali Murat Hacimustafaoglu
To determine normal values, repeatability, and interocular symmetry of optic nerve head measurements, three spectral-domain optical coherence tomography (SD-OCT) scans were obtained from 128 healthy Turkish children aged 5-17 years consecutively and prospectively. The mean disc area, rim area, cup volume, cup to disc area ratio, and vertical and horizontal cup to disc ratios were 2.30 ± 0.42 mm2 , 1.84 ± 0.45 mm2 , 0.09 ± 0.10 mm3 , 0.20 ± 0.13, 0.37 ± 0.17, and 0.45 ± 0.20, respectively. The intraclass correlation coefficients were >0...
April 2018: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29557834/anterior-chamber-angle-tissue-as-an-incidental-optical-coherence-tomography-finding-in-a-large-healthy-caucasian-child-population
#4
José Ignacio Fernández-Vigo, Lucía De-Pablo-Gómez-de-Liaño, Bachar Kudsieh, Cristina Fernández-Vigo, José Ángel Fernández-Vigo, Julián García-Feijóo
PURPOSE: To describe the presence of anterior chamber angle (ACA) tissue as an incidental optical coherence tomography (OCT) finding in healthy children. METHODS: For this cross-sectional study, we reviewed Fourier domain OCT images obtained in 422 children as candidates for inclusion in a prior study who visited our clinic for a routine vision test. The presence of angle tissue was assessed in the nasal and temporal quadrants. On tomographies showing angle tissue, several measurements were made including ACA width and trabecular meshwork (TM) length and size...
March 19, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29424610/oct-guided-management-of-subclinical-recurrent-retinoblastoma
#5
Marie-Claire Gaillard, Susan Houghton, Christina Stathopoulos, Francis L Munier
PURPOSE: Retinoblastoma (Rb) tumor recurrence in the papillary or macular region is a threat to life and visual prognosis respectively, making early detection indispensable. This study demonstrates the value of optical coherence tomography (OCT) in the early detection of subclinical tumor recurrence. METHODS: Since June 2012, hand-held SD-OCT (spectral domain Optical Coherence Tomography) of retro-equatorial foci, the optic head nerve and macula, is systematically performed under anesthesia in children treated and followed for Rb...
June 2018: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29203329/bruch-s-membrane-opening-on-optical-coherence-tomography-in-pediatric-papilledema-and-pseudopapilledema
#6
Atalie C Thompson, M Tariq Bhatti, Mays A El-Dairi
PURPOSE: To determine whether the diameter of Bruch's membrane opening (BMO) can distinguish mild papilledema from pseudopapilledema using optical coherence tomography (OCT). METHODS: The medical records of pediatric patients with pseudopapilledma due to optic nerve head (ONH) drusen, patients with papilledema, and normal control subjects were retrospectively reviewed. All eyes underwent OCT imaging of the BMO and retinal nerve fiber layer (RNFL). Transverse horizontal diameter of the BMO and papillary height were measured...
February 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29190238/longitudinal-changes-in-the-optic-nerve-head-and-retina-over-time-in-very-young-children-with-familial-exudative-vitreoretinopathy
#7
Jonghyun Lee, Mays A El-Dairi, Du Tran-Viet, Shwetha Mangalesh, Alexandria Dandridge, Kim Jiramongkolchai, Christian Viehland, Cynthia A Toth
PURPOSE: To explore vitreoretinal pathologies and their longitudinal changes visible on handheld optical coherence tomography (OCT) of young children with familial exudative vitreoretinopathy. METHODS: The authors retrospectively analyzed handheld OCT images for vitreoretinal interface and retinal abnormalities and optic nerve head (ONH) elevation. RESULTS: From 26 eyes of 16 children (mean age 32 months) with familial exudative vitreoretinopathy, 10 had ONH dragging on photographs, and in these, handheld OCT revealed temporal and anterior retinal displacement, prominent vitreopapillary adhesion or traction, and retinal nerve fiber layer thickening at ONH margins with adjacent retinal elevation...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29057163/characterization-of-long-working-distance-optical-coherence-tomography-for-imaging-of-pediatric-retinal-pathology
#8
Ruobing Qian, Oscar M Carrasco-Zevallos, Shwetha Mangalesh, Neeru Sarin, Lejla Vajzovic, Sina Farsiu, Joseph A Izatt, Cynthia A Toth
PURPOSE: We determined the feasibility of fovea and optic nerve head imaging with a long working distance (LWD) swept source optical coherence tomography (OCT) prototype in adults, teenagers, and young children. METHODS: A prototype swept source OCT system with a LWD (defined as distance from the last optical element of the imaging system to the eye) of 350 mm with custom fixation targets was developed to facilitate imaging of children. Imaging was performed in 49 participants from three age groups: 26 adults, 16 children 13 to 18 years old (teenagers), and seven children under 6 years old (young children) under an approved institutional review board protocol...
October 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29044060/interocular-symmetry-of-retinal-nerve-fiber-layer-and-optic-nerve-head-parameters-measured-by-cirrus-high-definition-optical-coherence-tomography-in-a-normal-pediatric-population
#9
Neelam Pawar, Devendra Maheshwari, Meenakshi Ravindran, Renagappa Ramakrishnan
PURPOSE: To determine interocular differences in the retinal nerve fiber layer (RNFL) and optic nerve head (ONH) parameters in a pediatric population using Cirrus high-definition optical coherence tomography (HD-OCT). METHODS: Seventy normal Indian children aged 5-17 years presenting to the Pediatric Clinic were included in this observational cross-sectional study. All subjects underwent a comprehensive ophthalmologic examination and an evaluation of the RNFL and ONH by Cirrus HD-OCT...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28941529/emerging-applications-of-optical-coherence-tomography-in-pediatric-optic-neuropathies
#10
Sidney M Gospe, M Tariq Bhatti, Mays A El-Dairi
Limited cooperation and attention span often lead to poorly reliable assessments of visual acuity and visual fields in children, making diagnosis and monitoring of pediatric optic neuropathies challenging. As a noninvasive imaging modality, optical coherence tomography (OCT) could offer particular utility in this patient population. OCT provides high-resolution characterization of the optic nerve head, peripapillary retinal nerve fiber layer, and cellular layers of the macula, all of which can be used to assess the severity of optic nerve disease qualitatively and quantitatively...
May 2017: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/28732589/accuracy-of-diagnostic-imaging-modalities-for-classifying-pediatric-eyes-as-papilledema-versus-pseudopapilledema
#11
Melinda Y Chang, Federico G Velez, Joseph L Demer, Laura Bonelli, Peter A Quiros, Anthony C Arnold, Alfredo A Sadun, Stacy L Pineles
PURPOSE: To identify the most accurate diagnostic imaging modality for classifying pediatric eyes as papilledema (PE) or pseudopapilledema (PPE). DESIGN: Prospective observational study. SUBJECTS: Nineteen children between the ages of 5 and 18 years were recruited. Five children (10 eyes) with PE, 11 children (19 eyes) with PPE owing to suspected buried optic disc drusen (ODD), and 3 children (6 eyes) with PPE owing to superficial ODD were included...
December 2017: Ophthalmology
https://www.readbyqxmd.com/read/28637781/detecting-optic-nerve-head-swelling-on-ultrasound-and-optical-coherence-tomography-in-children-and-young-people-an-observational-study
#12
Annegret Hella Dahlmann-Noor, Gillian W Adams, Moritz Claudius Daniel, Alison Davis, Joanne Hancox, Melanie Hingorani, Patricia Ibanez, Becky McPhee, Himanshu Patel, Marie Restori, Clare Roberts, Maria Theodorou, James Acheson
BACKGROUND: Following high-profile cases, referrals for evaluation of 'suspicious optic discs' to eye clinics in the UK have sharply increased, asking ophthalmologists to reliably distinguish between true and pseudopapilloedema. Optic nerve sheath dilatation (ONSD) on ocular ultrasound (US) is considered a reliable sign of true papilloedema, but this test is not widely available. Recently, anterior bowing of Bruch's membrane (BM) and increased retinal nerve fibre layer thickness on optical coherence tomography (OCT) have emerged as indicators of intracranial hypertension, and OCT is widely available...
March 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27585209/update-on-the-evaluation-of-pediatric-idiopathic-intracranial-hypertension
#13
REVIEW
Aubrey L Gilbert, Gena Heidary
PURPOSE OF REVIEW: Papilledema associated with idiopathic intracranial hypertension (IIH) may result in irreversible, progressive visual loss. The development of tools for the evaluation of pediatric patients with IIH is particularly relevant as many patients may not be able to comply with the detailed clinical evaluation utilized in adults for the treatment and management of this disease. The purpose of this review is to summarize relevant articles on the diagnostic tools used in evaluation and management of pediatric IIH...
November 2016: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/27552291/vigabatrin-toxicity-in-infancy-is-associated-with-retinal-defect-in-adolescence-a-prospective-observational-study
#14
Tom Wright, Ananthavalli Kumarappah, Aphrodite Stavropoulos, Arun Reginald, J Raymond Buncic, Carol A Westall
PURPOSE: The purpose was to determine whether vigabatrin (VGB) (Sabril)-attributed retinal toxicity defined by electroretinogram in early childhood is associated with visual system defect in adolescents after discontinuation of VGB. METHODS: This prospective cross-sectional study included 24 children previously treated with VGB and monitored in early childhood by electroretinogram for VGB-attributed retinal defects. Ten had been diagnosed with VGB-attributed retinal defect (Group I) and 14 had no VGB-attributed retinal defect (Group II)...
May 2017: Retina
https://www.readbyqxmd.com/read/27521172/optic-nerve-head-development-in-healthy-infants-and-children-using-handheld-spectral-domain-optical-coherence-tomography
#15
Aarti Patel, Ravi Purohit, Helena Lee, Viral Sheth, Gail Maconachie, Eleni Papageorgiou, Rebecca J McLean, Irene Gottlob, Frank A Proudlock
PURPOSE: To determine feasibility of optic nerve head (ONH) imaging and to characterize ONH development in full-term infants without sedation using handheld spectral-domain optical coherence tomography (SD OCT). DESIGN: Prospective cross-sectional study. PARTICIPANTS: Three hundred fifty-two children aged between 1 day and 13 years. METHODS: All participants were imaged using handheld SD OCT without sedation during a single scan session...
October 2016: Ophthalmology
https://www.readbyqxmd.com/read/27158616/retinal-nerve-fiber-layer-and-ganglion-cell-inner-plexiform-layer-thickness-in-children-with-obesity
#16
Selim Demir, Samet Özer, Sait Alim, Alper Güneş, Hüseyin Ortak, Resul Yılmaz
AIM: To evaluate retinal nerve fiber layer (RNFL) thickness analysis of peripapillary optic nerve head (PONH) and macula as well as ganglion cell-inner plexiform layer (GCIPL) thickness in obese children. METHODS: Eighty-five children with obesity and 30 controls were included in the study. The thicknesses of the PONH and macula of each subject's right eye were measured by high-resolution spectral-domain optic coherence tomography (OCT). RESULTS: The RNFL thicknesses of central macular and PONH were similar between the groups (all P>0...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/26917071/the-incidence-of-neovascular-membranes-and-visual-field-defects-from-optic-nerve-head-drusen-in-children
#17
Jared E Duncan, Sharon F Freedman, Mays A El-Dairi
PURPOSE: To evaluate the incidence of visual field defects and choroidal neovascular membranes (CNVM) in a cohort of pediatric patients with optic nerve head drusen (ONHD). METHODS: The medical records of children with ONHD seen at a single center from January 2012 to July 2014 were retrospectively reviewed to identify patients who had a dilated fundus examination, fundus photography, spectral domain optical coherence tomography (SD-OCT)/enhanced-depth imaging (EDI) of the optic nerve head (ONH), SITA fast 24-2 Humphrey visual field (HVF) testing, lumbar puncture, and ocular ultrasound...
February 2016: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/26795877/normative-spectral-domain-optical-coherence-tomography-data-in-healthy-turkish-children
#18
Fatma Betül Gürağaç, Yüksel Totan, Emre Güler, Aylin Tenlik, İhsan Gökhan Ertuğrul
PURPOSE: To determine the normative database of macular and retinal nerve fiber layer (RNFL) thickness parameters in healthy Turkish children by OCT. METHODS: 318 eyes of 318 children (138 boys, 183 girls) aged between 3 and 17 years were evaluated. The children were scanned by Cirrus HD-OCT (Carl Zeiss Meditec) to measure the macula, RNFL, and optic nerve head parameters. RESULTS: Axial length (AL) (p < 0.001, R(2 )= 0.08), spherical equivalent (SE) (p < 0...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/26691032/optic-nerve-morphology-in-normal-children
#19
COMPARATIVE STUDY
Devang L Bhoiwala, John W Simon, Preethi Raghu, Mala Krishnamoorthy, Amit Todani, Sai B Gandham, Steven Simmons
PURPOSE: To expand the normative database of pediatric eyes analyzed with the Optovue optical coherence tomography (OCT). METHODS: In a community-based, cross-sectional analysis, 77 healthy 5-year-old children were recruited from pediatric practices. No subject had any known ocular disorder. Their optic nerves were assessed using Optovue optical coherence tomography (OCT). Data were compared to the normative database obtained by Optovue for adults, ages 18-25, 40-45, and 55-60...
December 2015: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/26147983/optic-disc-change-during-childhood-myopic-shift-comparison-between-eyes-with-an-enlarged-cup-to-disc-ratio-and-childhood-glaucoma-compared-to-normal-myopic-eyes
#20
Hae-Young Lopilly Park, Sung Eun Kim, Sung Eum Kim, Chan Kee Park
BACKGROUND: Progressive disc tilting and the development or enlargement of peripapillary atrophy (PPA) are observed during a myopic shift in children. This could be related to the changes around the optic nerve head during eyeball elongation. If the biomechanical properties at or around the optic nerve head are changed after exposure to elevated intraocular pressure (IOP) in glaucoma eyes, different response of the disc tilting and PPA changes could take place during eyeball elongation by myopic shift...
2015: PloS One
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