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Intermittant fasting

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https://www.readbyqxmd.com/read/27909497/persistent-atrial-fibrillation-and-atrial-flutter-complicated-by-tachycardiomyopathy-because-of-intermittent-conduction-through-accessory-pathway
#1
L Valeri, A Coppolino, G Rossetti, A Vado, G Amoroso, G Bricco, A Battisti, L Correndo, S Dogliani, A Magliarditi, D Pancaldo, M De Benedictis, A Bassignana, B Doronzo
The term tachycardiomyopathy refers to a specific form of tachycardia-related cardiomyopathy caused by supraventricular or ventricular tachyarrhytmias that are both associated with ventricular rates higher than 120 bpm. The arrhythmias which are most frequently associated with these forms of heart disease are atrial fibrillation and atrial flutter, particularly found in the elderly population. The most frequent clinical manifestation is heart failure. In this case we are reporting a clinical case of a patient that came to our attention because of an episode of heart failure associated with atrial fibrillation and atrial flutter...
April 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27899768/effects-of-dietary-restriction-on-adipose-mass-and-biomarkers-of-healthy-aging-in-human
#2
Daniele Lettieri-Barbato, Esmeralda Giovannetti, Katia Aquilano
In developing countries the rise of obesity and obesity-related metabolic disorders, such as cardiovascular diseases and type 2 diabetes, reflects the changes in lifestyle habits and wrong dietary choices. Dietary restriction (DR) regimens have been shown to extend health span and lifespan in many animal models including primates. Identifying biomarkers predictive of clinical benefits of treatment is one of the primary goals of precision medicine. To monitor the clinical outcomes of DR interventions in humans, several biomarkers are commonly adopted...
November 29, 2016: Aging
https://www.readbyqxmd.com/read/27882110/intermittent-fasting-is-neuroprotective-in-focal-cerebral-ischemia-by-minimizing-autophagic-flux-disturbance-and-inhibiting-apoptosis
#3
Ji Heun Jeong, Kwang Sik Yu, Dong Ho Bak, Je Hun Lee, Nam Seob Lee, Young Gil Jeong, Dong Kwan Kim, Jwa-Jin Kim, Seung-Yun Han
Previous studies have demonstrated that autophagy induced by caloric restriction (CR) is neuroprotective against cerebral ischemia. However, it has not been determined whether intermittent fasting (IF), a variation of CR, can exert autophagy-related neuroprotection against cerebral ischemia. Therefore, the neuroprotective effect of IF was evaluated over the course of two weeks in a rat model of focal cerebral ischemia, which was induced by middle cerebral artery occlusion and reperfusion (MCAO/R). Specifically, the role of autophagy modulation as a potential underlying mechanism for this phenomenon was investigated...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27859020/systemic-inflammation-in-acute-intermittent-porphyria-a-case-control-study
#4
E Storjord, J A Dahl, A Landsem, H Fure, J K Ludviksen, S Goldbeck-Wood, B O Karlsen, K S Berg, T E Mollnes, E W Nielsen, O-L Brekke
This study aimed to examine whether acute intermittent porphyria (AIP) is associated with systemic inflammation and whether the inflammation correlates with disease activity. A case-control study with 50 AIP cases and healthy age-, sex- and place of residence matched controls was performed. Plasma cytokines, insulin and C-peptide were analyzed after an overnight fast using multiplex assay. Long pentraxin-3 (PTX3) and complement activation products (C3bc and TCC) were analyzed using ELISA. Urine porphobilinogen ratio (U-PBG, µmol/mmol creatinine), hematological and biochemical tests were performed using routine methods...
November 8, 2016: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/27855235/sirolimus-therapy-in-a-child-with-partially-diazoxide-responsive-hyperinsulinaemic-hypoglycaemia
#5
Kah-Yin Loke, Andrew Sng Anjian, Yvonne Lim Yijuan, Cindy Ho Wei Li, Maria Güemes, Khalid Hussain
: Hyperinsulinaemic hypoglycaemia (HH), which causes persistent neonatal hypoglycaemia, can result in neurological damage and it's management is challenging. Diazoxide is the first-line treatment, albeit not all patients will fully respond to it, as episodes of hypoglycaemia may persist and it entails unpleasant adverse effects. Sirolimus, an mTOR inhibitor, has reportedly been successful in treating children with severe diffuse HH, thus obviating the need for pancreatectomy. We report a girl with HH, with a novel heterozygous ABCC8 gene missense mutation (c...
2016: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/27835792/intermittent-fasting-reduces-body-fat-but-exacerbates-hepatic-insulin-resistance-in-young-rats-regardless-of-high-protein-and-fat-diets
#6
Sunmin Park, Kyung Min Yoo, Joo Suk Hyun, Suna Kang
Intermittent fasting (IMF) is a relatively new dietary approach to weight management, although the efficacy and adverse effects have not been full elucidated and the optimal diets for IMF are unknown. We tested the hypothesis that a one-meal-per-day intermittent fasting with high fat (HF) or protein (HP) diets can modify energy, lipid, and glucose metabolism in normal young male Sprague-Dawley rats with diet-induced obesity or overweight. Male rats aged 5 weeks received either HF (40% fat) or HP (26% protein) diets ad libitum (AL) or for 3 h at the beginning of the dark cycle (IMF) for 5 weeks...
October 15, 2016: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/27832862/time-restricted-feeding-improves-insulin-resistance-and-hepatic-steatosis-in-a-mouse-model-of-postmenopausal-obesity
#7
Heekyung Chung, Winjet Chou, Dorothy D Sears, Ruth E Patterson, Nicholas J G Webster, Lesley G Ellies
BACKGROUND: Menopause is associated with significant hormonal changes that result in increased total body fat and abdominal fat, amplifying the risk for metabolic syndrome and diseases such as diabetes, cardiovascular disease and cancer in postmenopausal women. Intermittent fasting regimens hold significant health benefit promise for obese humans, however, regimens that include extreme daytime calorie restriction or daytime fasting are generally associated with hunger and irritability, hampering long-term compliance and adoption in the clinical setting...
December 2016: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/27810402/impact-of-intermittent-fasting-on-health-and-disease-processes
#8
REVIEW
Mark P Mattson, Valter D Longo, Michelle Harvie
Humans in modern societies typically consume food at least three times daily, while laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns often leads to metabolic morbidities (insulin resistance, excessive accumulation of visceral fat, etc.), particularly when associated with a sedentary lifestyle. Because animals, including humans, evolved in environments where food was relatively scarce, they developed numerous adaptations that enabled them to function at a high level, both physically and cognitively, when in a food-deprived/fasted state...
October 31, 2016: Ageing Research Reviews
https://www.readbyqxmd.com/read/27805239/effects-of-ramadan-intermittent-fasting-on-north-african-children-s-heart-rate-and-oxy-haemoglobin-saturation-at-rest-and-during-sub-maximal-exercise
#9
Mohamed Amine Fenneni, Imed Latiri, Asma Aloui, Sonia Rouatbi, Karim Chamari, Helmi Ben Saad
AIM: To examine the effects of Ramadan intermittent fasting (RIF) on the heart rate (HR) and oxyhaemoglobin saturation levels (oxy-sat) of boys at rest and during a six-minute walking test (6MWT). METHODS: Eighteen boys (age: 11.9 ± 0.8 years, height: 153.00 ± 8.93 cm, body mass: 55.4 ± 18.2 kg), who fasted the entire month of Ramadan in 2012 for the first time in their lives, were included. The experimental protocol comprised four testing phases: two weeks before Ramadan (pre-R), the end of the second week of Ramadan (R-2), the end of the fourth week of Ramadan (R-4), and 10 to 12 days after the end of Ramadan (post-R)...
October 21, 2016: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/27803421/tuberculous-fasciitis-in-polymyositis-a-rare-case-of-extrapulmonary-tuberculosis
#10
Ikue Nagayama, Katsuyuki Nagatoya, Yu Kurahara, Akira Mega, Masashi Morita, Ryota Haga, Yu Yamanouchi, Yoshito Yamaguchi, Tatsufumi Oka, Atsushi Yamauchi
A 71-year-old woman with polymyositis presenting with left thigh pain and an intermittent fever was admitted to Osaka Rosai Hospital. We initially diagnosed that her pain and fever were caused by a soft tissue infection because her polymyositis was controlled. She did not respond to various antibiotic therapies. Chest computed tomography demonstrated miliary tuberculosis (TB). Ziehl-Neelsen staining of liver biopsy specimens revealed epithelioid cell granuloma and acid-fast bacilli. Therefore, we finally diagnosed the lesion as TB fasciitis that improved with anti-TB drug therapy...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27803153/single-molecule-measurements-of-viral-ssrna-packaging
#11
Kalle J Hanhijärvi, Gabija Ziedaite, Dennis H Bamford, Edward Hæggström, Minna M Poranen
Genome packaging of double-stranded RNA (dsRNA) phages has been widely studied using biochemical and molecular biology methods. We adapted the existing in vitro packaging system of one such phage for single-molecule experimentation. To our knowledge, this is the first attempt to study the details of viral RNA packaging using optical tweezers. Pseudomonas phage phi6 is a dsRNA virus with a tripartite genome. Positive-sense (+) single-stranded RNA (ssRNA) genome precursors are packaged into a preformed procapsid (PC), where negative-strands are synthesized...
November 1, 2016: RNA
https://www.readbyqxmd.com/read/27781439/synchronization-of-mobile-chaotic-oscillator-networks
#12
Naoya Fujiwara, Jürgen Kurths, Albert Díaz-Guilera
We study synchronization of systems in which agents holding chaotic oscillators move in a two-dimensional plane and interact with nearby ones forming a time dependent network. Due to the uncertainty in observing other agents' states, we assume that the interaction contains a certain amount of noise that turns out to be relevant for chaotic dynamics. We find that a synchronization transition takes place by changing a control parameter. But this transition depends on the relative dynamic scale of motion and interaction...
September 2016: Chaos
https://www.readbyqxmd.com/read/27773293/sonoluminescence-and-dynamics-of-cavitation-bubble-populations-in-sulfuric-acid
#13
Andrea Thiemann, Frank Holsteyns, Carlos Cairós, Robert Mettin
The detailed link of liquid phase sonochemical reactions and bubble dynamics is still not sufficiently known. To further clarify this issue, we image sonoluminescence and bubble oscillations, translations, and shapes in an acoustic cavitation setup at 23kHz in sulfuric acid with dissolved sodium sulfate and xenon gas saturation. The colour of sonoluminescence varies in a way that emissions from excited non-volatile sodium atoms are prominently observed far from the acoustic horn emitter ("red region"), while such emissions are nearly absent close to the horn tip ("blue region")...
January 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/27737674/effects-of-eight-weeks-of-time-restricted-feeding-16-8-on-basal-metabolism-maximal-strength-body-composition-inflammation-and-cardiovascular-risk-factors-in-resistance-trained-males
#14
Tatiana Moro, Grant Tinsley, Antonino Bianco, Giuseppe Marcolin, Quirico Francesco Pacelli, Giuseppe Battaglia, Antonio Palma, Paulo Gentil, Marco Neri, Antonio Paoli
BACKGROUND: Intermittent fasting (IF) is an increasingly popular dietary approach used for weight loss and overall health. While there is an increasing body of evidence demonstrating beneficial effects of IF on blood lipids and other health outcomes in the overweight and obese, limited data are available about the effect of IF in athletes. Thus, the present study sought to investigate the effects of a modified IF protocol (i.e. time-restricted feeding) during resistance training in healthy resistance-trained males...
October 13, 2016: Journal of Translational Medicine
https://www.readbyqxmd.com/read/27711219/assessing-basal-and-acute-autophagic-responses-in-the-adult-drosophila-nervous-system-the-impact-of-gender-genetics-and-diet-on-endogenous-pathway-profiles
#15
Eric P Ratliff, Roxanne W Kotzebue, Brandon Molina, Ruth E Mauntz, Arysa Gonzalez, Ayeh Barekat, Nadja El-Mecharrafie, Shannon Garza, Michael A Gurney, Madhulika Achal, Phyllis-Jean Linton, Greg L Harris, Kim D Finley
The autophagy pathway is critical for the long-term homeostasis of cells and adult organisms and is often activated during periods of stress. Reduced pathway efficacy plays a central role in several progressive neurological disorders that are associated with the accumulation of cytotoxic peptides and protein aggregates. Previous studies have shown that genetic and transgenic alterations to the autophagy pathway impacts longevity and neural aggregate profiles of adult Drosophila. In this study, we have identified methods to measure the acute in vivo induction of the autophagy pathway in the adult fly CNS...
2016: PloS One
https://www.readbyqxmd.com/read/27706509/atrioventricular-accessory-pathways-mechanisms-electrocardiograms-and-associated-arrhythmias
#16
Eliana Hanna Deschamps, Elias B Hanna
An atrioventricular accessory pathway (AP) may be manifest or concealed. When manifest, it leads to preexcitation on the baseline electrocardiogram, which is called the Wolff-Parkinson-White pattern. The degree of preexcitation varies according to the relative conduction speed of the atrioventricular node versus the AP, the AP location, and the AP refractory period. This explains that even a manifest AP may lead to only intermittent preexcitation. The AP conducts faster than the atrioventricular node but has a longer refractory period, which allows the initiation of a reentrant arrhythmia called atrioventricular reciprocating tachycardia...
October 2016: Southern Medical Journal
https://www.readbyqxmd.com/read/27704908/effect-of-exercise-intensity-and-mode-on-acute-appetite-control-in-men-and-women
#17
Valéria Leme Gonçalves Panissa, Ursula Ferreira Julio, Felipe Hardt, Carolina Kurashima, Fábio Santos Lira, Monica Yuri Takito, Emerson Franchini
The aim of this study was to compare the effects of exercise intensity on appetite control: relative energy intake (energy intake minus the energy expenditure of exercise; REI), hunger scores, and appetite-regulating hormones in men and women. Eleven men and 9 women were submitted to 4 experimental sessions: high-intensity intermittent all-out exercise (HIIE-A) for 60 × 8 s interspersed by 12 s of passive recovery; high-intensity intermittent exercise (HIIE) at 100% of maximal load attained in incremental test; steady-state exercise at 60% of maximal load, matched by work done; and a control session...
July 7, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/27678302/adiponectin-protects-the-rats-liver-against-chronic-intermittent-hypoxia-induced-injury-through-amp-activated-protein-kinase-pathway
#18
Wenxiao Ding, Qiang Zhang, Yanbin Dong, Ning Ding, Hanpeng Huang, Xianji Zhu, Sean Hutchinson, Xingya Gao, Xilong Zhang
This study was performed to assess the effect of chronic intermittent hypoxia (CIH) on the liver, the associated mechanisms and the potential therapeutic roles of adiponectin (Ad). Sixty rats were randomly assigned to four groups: the normal control (NC), NC and Ad supplement (NC + Ad), CIH, and CIH and Ad supplement (CIH + Ad) groups. The rats in the CIH and CIH + Ad groups were exposed to a hypoxic environment for 4 months. Rats in the NC + Ad and CIH + Ad groups were also treated with an intravenous injection of Ad (10 ug), twice a week...
September 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27677560/comparison-of-emergency-department-wait-times-in-adults-with-sickle-cell-disease-versus-other-painful-etiologies
#19
Dianne Pulte, Paris B Lovett, David Axelrod, Albert Crawford, John McAna, Rhea Powell
Sickle cell disease is characterized by intermittent painful crises often requiring treatment in the emergency department (ED). Past examinations of time-to-provider (TTP) in the ED for patients with sickle cell disease demonstrated that these patients may have longer TTP than other patients. Here, we examine TTP for patients presenting for emergency care at a single institution, comparing patients with sickle cell disease to both the general population and to those with other painful conditions, with examination of both institutional and patient factors that might affect wait times...
September 28, 2016: Hemoglobin
https://www.readbyqxmd.com/read/27660746/acute-intermittent-porphyria-presenting-with-posterior-reversible-encephalopathy-syndrome-and-lateralized-periodic-discharges-plus-fast-activity-on-eeg
#20
Diosely C Silveira, Mahrukh Bashir, Joshua Daniel, Michelle H Lucena, Frank Bonpietro
We report on a 20-year-old patient with a 6-month history of recurrent abdominal pain and a 3-day history of vomiting, hypertension, seizures, and encephalopathy. The brain MRI showed posterior reversible encephalopathy syndrome, and continuous EEG (cEEG) monitoring showed lateralized periodic discharges plus fast activity. Comprehensive CSF studies were negative. Because of severe abdominal pain without a definite etiology, we requested urine porphobilinogen and serum and fecal porphyrins, which suggested acute intermittent porphyria (AIP)...
2016: Epilepsy & Behavior Case Reports
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