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https://www.readbyqxmd.com/read/29453111/febrile-infection-related-epilepsy-syndrome-fires-therapeutic-complications-long-term-neurological-and-neuroimaging-follow-up
#1
Hsiu-Fen Lee, Ching-Shiang Chi
PURPOSE: To understand the long-term neurological outcomes and chronological changes of brain MRIs in patients with febrile infection-related epilepsy syndrome (FIRES). METHODS: From December 2000 to May 2016, 29 patients diagnosed with FIRES were collected retrospectively. The demographic distribution, clinical manifestations, neuroimaging findings, and treatment methodology were described. Follow-up clinical outcomes and chronological evolution of neuroimaging findings were analyzed...
February 6, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29450462/epidemiology-of-adult-dsm-5-major-depressive-disorder-and-its-specifiers-in-the-united-states
#2
Deborah S Hasin, Aaron L Sarvet, Jacquelyn L Meyers, Tulshi D Saha, W June Ruan, Malka Stohl, Bridget F Grant
Importance: No US national data are available on the prevalence and correlates of DSM-5-defined major depressive disorder (MDD) or on MDD specifiers as defined in DSM-5. Objective: To present current nationally representative findings on the prevalence, correlates, psychiatric comorbidity, functioning, and treatment of DSM-5 MDD and initial information on the prevalence, severity, and treatment of DSM-5 MDD severity, anxious/distressed specifier, and mixed-features specifier, as well as cases that would have been characterized as bereavement in DSM-IV...
February 14, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29448220/trunk-postural-balance-and-low-back-pain-reliability-and-relationship-with-clinical-changes-following-a-lumbar-stabilization-exercise-program
#3
Ali Shahvarpour, Dany Gagnon, Richard Preuss, Sharon M Henry, Christian Larivière
Lumbar stabilization programs reduce pain and disability, but the mechanisms of action underlying this treatment are unknown. Trunk postural control during unstable sitting represents a surrogate measure of motor control mechanisms involved to maintain the dynamic stability of the spine. This exploratory study aimed to determine the reliability of trunk postural control measures over an 8-week interval, their sensitivity to low back pain status and treatment and their relationship with clinical outcomes. Trunk postural control measures were determined in patients with low back pain before and after an 8-week lumbar stabilization exercise program...
February 9, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29441694/presynaptic-congenital-myasthenic-syndrome-with-altered-synaptic-vesicle-homeostasis-linked-to-compound-heterozygous-sequence-variants-in-rph3a
#4
Ricardo A Maselli, Jessica Vázquez, Leah Schrumpf, Juan Arredondo, Marian Lara, Jonathan B Strober, Peter Pytel, Robert L Wollmann, Michael Ferns
BACKGROUND: Monogenic defects of synaptic vesicle (SV) homeostasis have been implicated in many neurologic diseases, including autism, epilepsy, and movement disorders. In addition, abnormal vesicle exocytosis has been associated with several endocrine dysfunctions. METHODS: We report an 11 year old girl with learning disabilities, tremors, ataxia, transient hyperglycemia, and muscle fatigability responsive to albuterol sulfate. Failure of neuromuscular transmission was confirmed by single fiber electromyography...
February 14, 2018: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/29441282/specific-learning-disability-in-mathematics-a-comprehensive-review
#5
REVIEW
Neelkamal Soares, Teresa Evans, Dilip R Patel
Math skills are necessary for success in the childhood educational and future adult work environment. This article reviews the changing terminology for specific learning disabilities (SLD) in math and describes the emerging genetics and neuroimaging studies that relate to individuals with math disability (MD). It is important to maintain a developmental perspective on MD, as presentation changes with age, instruction, and the different models (educational and medical) of identification. Intervention requires a systematic approach to screening and remediation that has evolved with more evidence-based literature...
January 2018: Translational Pediatrics
https://www.readbyqxmd.com/read/29436893/a-literature-review-on-the-experience-of-long-term-mental-illness
#6
Elizabeth Collier, Maria J Grant
PURPOSE: To illuminate long-term experiences of mental illness from both research and autobiographical accounts. DESIGN: A literature review of English-language papers, 1950-2014, relating to the experience of long-term mental illness indexed in AgeInfo, AMED, ASSIA, British Nursing Index (BNI), CINAHL, MEDLINE, PsycEXTRA, and PsychINFO. FINDINGS: Twenty-five research papers and nine autobiographic accounts met the review criteria. Thematic analysis revealed nine themes: fear, explanation seeking, stigma, disability, coping strategies, control, support, change and learning, and life history...
February 13, 2018: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/29432607/positive-psychology-in-research-with-the-deaf-community-an-idea-whose-time-has-come
#7
Amy Szarkowski, Patrick Brice
The emergence of positive psychology as an approach to studying what makes life worth living has inspired a new wave of research. Studies have focused on the prevalence and degree of positive attributes, attitudes, and characteristics in the wider population. Increasingly, lessons learned from positive psychology have been applied to understanding the more diverse experiences of individuals belonging to various groups. Only recently, however, has positive psychology research incorporated a disability perspective, and very little research from a positive psychology stance has been conducted with deaf people...
February 8, 2018: Journal of Deaf Studies and Deaf Education
https://www.readbyqxmd.com/read/29432115/the-pediatric-smartshoe-wearable-sensor-system-for-ambulatory-monitoring-of-physical-activity-and-gait
#8
Nagaraj Hegde, Ting Zhang, Gitendra Uswatte, Edward Taub, Joydip Barman, Staci McKay, Andrea Taylor, David M Morris, Angi Griffin, Edward S Sazonov
Cerebral palsy (CP) is a group of nonprogressive neuro-developmental conditions occurring in early childhood that causes movement disorders and physical disability. Measuring activity levels and gait patterns is an important aspect of CP rehabilitation programs. Traditionally, such programs utilize commercially available laboratory systems, which cannot to be utilized in community living. In this study, a novel, shoe-based, wearable sensor system (pediatric SmartShoe) was tested on 11 healthy children and 10 children with CP to validate its use for monitoring of physical activity and gait...
February 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29422020/cognitive-medicine-a-new-approach-in-health-care-science
#9
Anders Wallin, Petronella Kettunen, Per M Johansson, Ingibjörg H Jonsdottir, Christer Nilsson, Michael Nilsson, Marie Eckerström, Arto Nordlund, Lars Nyberg, Katharina S Sunnerhagen, Johan Svensson, Beata Terzis, Lars-Olof Wahlund, H Georg Kuhn
BACKGROUND: The challenges of today's society call for more knowledge about how to maintain all aspects of cognitive health, such as speed/attention, memory/learning, visuospatial ability, language, executive capacity and social cognition during the life course. MAIN TEXT: Medical advances have improved treatments of numerous diseases, but the cognitive implications have not been sufficiently addressed. Disability induced by cognitive dysfunction is also a major issue in groups of patients not suffering from Alzheimer's disease or related disorders...
February 8, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29417434/mothers-experiences-of-a-women-s-health-and-empowerment-program-for-mothers-of-a-child-with-a-disability
#10
Helen M Bourke-Taylor, Fiona M Jane
Substantial research identifies mothers of children with a disability as a vulnerable group with compromised health outcomes and restrictions for their own self-care, social, economic and leisure participation. This study investigated perceptions and experiences of mothers following attendance at health education and empowerment workshops (Healthy Mothers Healthy Families). Mixed methods evaluated mothers' experiences. A pragmatic qualitative approach was applied to data analysis of interviews with mothers (N = 19)...
February 7, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29412537/health-promotion-for-young-people-with-profound-and-multiple-learning-disabilities
#11
Kathy Davis, Simone Carter, Elizabeth Myers, Nicola Rocca
Research confirms that children and young people with severe learning disabilities do not have the same level of access to high-quality care, health education and health promotion activities as children and young people without disabilities. This article discusses a quality improvement, action research project to investigate alternative approaches to health promotion that enhance the health and well-being of children and young people with complex neurodisabilities. The project involved assessment of school records and completion by staff of an eight-question survey...
February 7, 2018: Nursing Children and Young People
https://www.readbyqxmd.com/read/29408160/ten-year-prediction-of-suicide-death-using-cox-regression-and-machine-learning-in-a-nationwide-retrospective-cohort-study-in-south-korea
#12
Soo Beom Choi, Wanhyung Lee, Jin-Ha Yoon, Jong-Uk Won, Deok Won Kim
BACKGROUND: Death by suicide is a preventable public health concern worldwide. The aim of this study is to investigate the probability of suicide death using baseline characteristics and simple medical facility visit history data using Cox regression, support vector machines (SVMs), and deep neural networks (DNNs). METHOD: This study included 819,951 subjects in the National Health Insurance Service (NHIS)-Cohort Sample Database from 2004 to 2013. The dataset was divided randomly into two independent training and validation groups...
January 31, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29406451/is-use-of-a-psychological-workbook-associated-with-improved-disabilities-of-the-arm-shoulder-and-hand-scores-in-patients-with-distal-radius-fracture
#13
Stuart Goudie, Diane Dixon, Gail McMillan, David Ring, Margaret McQueen
BACKGROUND: Symptom intensity and magnitude of limitations correlate with stress, distress, and less effective coping strategies. It is unclear if interventions to target these factors can be used to improve outcomes after distal radius fracture in either the short- or longer term. QUESTIONS/PURPOSES: (1) Are there any factors (including the use of a workbook aimed at optimizing psychological response to injury, demographic, radiographic, medical, or psychosocial) associated with improved Disabilities of the Arm, Shoulder and Hand (DASH) and Numerical Rating Scale pain (NRS pain) scores at 6 weeks after management of distal radius fracture? (2) Are any of these factors associated with improved DASH and NRS pain scores at 6 months after management of distal radius fracture? METHODS: We conducted a double-blind randomized controlled trial comparing a workbook designed to optimize rehabilitation by improving psychological response to injury using recognized psychological techniques (the LEARN technique and goal setting) versus a workbook containing details of stretching exercises in the otherwise routine management of distal radius fracture...
February 2, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29404228/separating-visuospatial-from-visuomotor-coordination-in-skill-estimation-in-learning-disabled-children-the-eta-mu-model
#14
Carlo Aleci, Marzia Piccoli, Valentina Melotti, Elena Melis, Lorenzo Canavese
Purpose A model aimed at detecting the proportion of visuoperceptive and visuomotor coordination impairment in children with ascertained or suspected learning disability is described. The final purpose is to provide customized rehabilitation programs. Methods In this pilot study, four children (8-9 years) were administered a set of standardized tests to evaluate their ability to perform visuoperceptive and visuomotor tasks. Depending on the individual outcomes, two indexes have been computed from the resulting z-scores: η (Eta) that quantifies the visuoperceptive impairment, and μ (Mu) that expresses the alteration in visuomotor coordination...
December 1, 2017: Curēus
https://www.readbyqxmd.com/read/29401238/maneuvering-together-apart-and-at-odds-residents-care-convoys-in-assisted-living
#15
Candace L Kemp, Mary M Ball, Jennifer Craft Morgan, Patrick J Doyle, Elisabeth O Burgess, Molly M Perkins
Objectives: Frail and disabled individuals such as assisted living residents are embedded in "care convoys" comprised of paid and unpaid caregivers. We sought to learn how care convoys are configured and function in assisted living and understand how and why they vary and with what resident and caregiver outcomes. Method: We analyzed data from a qualitative study involving formal in-depth interviews, participant observation and informal interviewing, and record review...
February 1, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29400681/using-association-rules-to-measure-subjective-organization-after-acquired-brain-injury
#16
Frederick Parente, John-Christopher Finley
BACKGROUND: Subjective Organization (SO) refers to the human tendency to impose organization on our environment. Persons with Acquired Brain Injury (ABI) often lose the ability to organize however, there are no performance based measures of organization that can be used to document this disability. OBJECTIVE: The authors propose a method of association rule analysis (AR) that can be used as a clinical tool for assessing a patient's ability to organize. METHOD: Twenty three patients with ABI recalled a list of twelve unrelated nouns over twelve study and test trials...
2018: NeuroRehabilitation
https://www.readbyqxmd.com/read/29395075/otud7a-knockout-mice-recapitulate-many-neurological-features-of-15q13-3-microdeletion-syndrome
#17
Jiani Yin, Wu Chen, Eugene S Chao, Sirena Soriano, Li Wang, Wei Wang, Steven E Cummock, Huifang Tao, Kaifang Pang, Zhandong Liu, Fred A Pereira, Rodney C Samaco, Huda Y Zoghbi, Mingshan Xue, Christian P Schaaf
15q13.3 microdeletion syndrome is characterized by a wide spectrum of neurodevelopmental disorders, including developmental delay, intellectual disability, epilepsy, language impairment, abnormal behaviors, neuropsychiatric disorders, and hypotonia. This syndrome is caused by a deletion on chromosome 15q, which typically encompasses six genes. Here, through studies on OTU deubiquitinase 7A (Otud7a) knockout mice, we identify OTUD7A as a critical gene responsible for many of the cardinal phenotypes associated with 15q13...
February 1, 2018: American Journal of Human Genetics
https://www.readbyqxmd.com/read/29392094/review-of-the-current-management-of-pressure-ulcers
#18
REVIEW
Tatiana V Boyko, Michael T Longaker, George P Yang
Significance: The incidence of pressure ulcers is increasing due to our aging population and the increase in the elderly living with disability. Learning how to manage pressure ulcers appropriately is increasingly important for all professionals in wound care. Recent Advances: Many new dressings and treatment modalities have been developed over the recent years and the goal of this review is to highlight their benefits and drawbacks to help providers choose their tools appropriately. Critical Issues: Despite an increased number of therapies available on the market, none has demonstrated any clear benefit over the others and pressure ulcer treatment remains frustrating and time-consuming...
February 1, 2018: Advances in Wound Care
https://www.readbyqxmd.com/read/29391206/long-term-outcomes-of-a-large-prospective-observational-cohort-of-older-adults-with-back-pain
#19
Jeffrey G Jarvik, Laura S Gold, Katherine Tan, Janna L Friedly, Srdjan S Nedeljkovic, Bryan A Comstock, Richard A Deyo, Judith A Turner, Brian W Bresnahan, Sean D Rundell, Kathryn T James, David R Nerenz, Andrew L Avins, Zoya Bauer, Larry Kessler, Patrick J Heagerty
BACKGROUND CONTEXT: Although back pain is common among older adults, there is relatively little research on the course of back pain in this age group. PURPOSE: Our primary goals were to report 2-year outcomes of older adults initiating primary care for back pain and to examine the relative importance of patient factors vs. medical interventions in predicting 2-year disability and pain. STUDY DESIGN/SETTING: Predictive model using data from a prospective, observational cohort from a primary care setting...
January 29, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29390923/maternal-overnutrition-leads-to-cognitive-and-neurochemical-abnormalities-in-c57bl-6-mice
#20
Christian Wolfrum, Daria Peleg-Raibstein
OBJECTIVES: Epidemiological studies have linked maternal obesity with metabolic as well as psychiatric disorders in the progeny. However, very little is known how maternal overnutrition may affect the cognitive abilities of the offspring. METHODS: Here, we tested the hypothesis whether maternal high-fat diet (HFD) exposure in mice may induce long-term cognitive impairments and neurochemical dysfunctions in the offspring during different age trajectories. RESULTS: We found that maternal HFD led to cognitive disabilities in adult offspring compared to controls...
February 1, 2018: Nutritional Neuroscience
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