Adrian A Epstein, Sara N Janos, Luca Menozzi, Kelly Pegram, Vaibhav Jain, Logan C Bisset, Joseph T Davis, Samantha Morrison, Aswathy Shailaja, Yingqiu Guo, Agnes S Chao, Khadar Abdi, Blaire Rikard, Junjie Yao, Simon G Gregory, Kimberley Fisher, Rick Pittman, Al Erkanli, Kathryn E Gustafson, Caroline W T Carrico, William F Malcolm, Terrie E Inder, C Michael Cotten, Trevor D Burt, Mari L Shinohara, Charles M Maxfield, Eric J Benner
Brain injury is highly associated with preterm birth. Complications of prematurity, including spontaneous or necrotizing enterocolitis (NEC)-associated intestinal perforations, are linked to lifelong neurologic impairment, yet the mechanisms are poorly understood. Early diagnosis of preterm brain injuries remains a significant challenge. Here, we identified subventricular zone echogenicity (SVE) on cranial ultrasound in preterm infants following intestinal perforations. The development of SVE was significantly associated with motor impairment at 2 years...
March 22, 2024: Cell Stem Cell