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https://www.readbyqxmd.com/read/28805967/prognostic-value-of-exercise-capacity-among-men-undergoing-pharmacologic-treatment-for-erectile-dysfunction-the-fit-project
#1
Robert V Same, Mahmoud Al Rifai, David I Feldman, Kevin L Billups, Clinton A Brawner, Zeina A Dardari, Jonathan K Ehrman, Steven J Keteyian, Mouaz H Al-Mallah, Michael J Blaha
BACKGROUND: Vascular erectile dysfunction (ED) has been identified as a potentially useful risk factor for predicting future cardiovascular events, particularly in younger men. Because these men typically score more favorably on traditional cardiovascular disease risk assessment tools, there exists a gap in knowledge for how to most appropriately identify those men who would benefit from more aggressive treatments. To date, no studies have examined the impact of fitness on cardiovascular outcomes in men with ED...
August 14, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28805343/rest-and-exercise-hemodynamic-and-metabolic-findings-in-active-duty-soldiers-referred-for-cardiac-catheterization-to-exclude-heart-disease-insights-from-past-invasive-cardiopulmonary-exercise-testing-using-multisensor-high-fidelity-catheters
#2
James A Watts, Faith R Kelly, Terry D Bauch, Joseph P Murgo, Bernard J Rubal
OBJECTIVE: This study describes results of iCPET from the past, which used submaximal stress and multisensor high-fidelity catheters to exclude heart disease in a unique population of young adults. BACKGROUND: There has been resurgence in comprehensive hemodynamic evaluation of complex cardiovascular patients. Although dynamic assessments during cardiac catheterization have become commonplace, there remains limited information regarding left and right heart hemodynamic changes during supine exercise in young adults...
May 8, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28803675/the-yale-fitness-intervention-trial-in-female-cancer-survivors-cardiovascular-and-physiological-outcomes
#3
M Tish Knobf, Sangchoon Jeon, Barbara Smith, Lyndsay Harris, Siobhan Thompson, Mitchel R Stacy, Karl Insogna, Albert J Sinusas
BACKGROUND: Induced premature menopause and cardio-toxic therapy increase cardiovascular disease risk in female cancer survivors. OBJECTIVE: To compare the effects of a 12 month aerobic-resistance fitness center intervention to home based physical activity on cardiovascular function and metabolic risk factors. METHODS: Subjects (N = 154) who had completed primary and/or adjuvant chemotherapy (past 3 years) were randomized to a fitness center intervention or a home based group...
August 10, 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28802509/value-of-strain-imaging-and-maximal-oxygen-consumption-in-patients-with-hypertrophic-cardiomyopathy
#4
Kegan J Moneghetti, Davide Stolfo, Jeffrey W Christle, Yukari Kobayashi, Gherardo Finocchiaro, Gianfranco Sinagra, Jonathan Myers, Euan A Ashley, Francois Haddad, Matthew T Wheeler
Longitudinal strain (LS) has been shown to be predictive of outcome in hypertrophic cardiomyopathy (HC). Percent predicted peak oxygen uptake (ppVO2), among other cardiopulmonary exercise testing (CPX) metrics, is a strong predictor of prognosis in HC. However, there has been limited investigation into the combination of LS and CPX metrics. This study sought to determine how LS and parameters of exercise performance contribute to prognosis in HC. One hundred and thirty-one consecutive patients with HC who underwent CPX and stress echocardiography were included...
July 17, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28801799/double-versus-single-source-left-sided-coronary-revascularization-using-bilateral-internal-thoracic-artery-graft-alone
#5
Giuseppe Gatti, Gianluca Castaldi, Marco Morosin, Irena Tavcar, Manuel Belgrano, Bernardo Benussi, Gianfranco Sinagra, Aniello Pappalardo
Left-sided coronary revascularization with bilateral internal thoracic artery (BITA) graft is performed usually either with an in situ (double source) or Y-graft configuration (single source). Two hundred fifty-three (mean age, 67.1 ± 9.5 years) patients underwent isolated left-sided coronary revascularization with BITA graft alone at the present authors' institution (2000-2015). Skeletonized BITA grafts were used either in an in situ (n = 199) or Y-graft configuration (n = 54). Forty pairs were identified with the propensity score-matching...
August 11, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28801525/exercise-of-obese-mice-induces-cardioprotection-and-oxygen-sparing-in-hearts-exposed-to-high-fat-load
#6
Neoma T Boardman, Anne Dragøy Hafstad, Jim Lund, Line Rossvoll, Ellen Aasum
Exercise training is a potent, therapeutic approach in obesity and diabetes that exerts protective effects against development of diabetic cardiomyopathy and ischemic-injury. Acute increases in circulating fatty acids (FAs) during an ischemic insult can challenge the heart, as high FA-load is considered to have adverse cardiac effects. In the present study, we tested the hypothesis that exercise-induced cardiac effects in diet-induced obese mice are abrogated by an acute high FA-load. Diet-induced obese mice were fed a high-fat diet (HFD) for 20 weeks...
August 11, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28801407/the-boundaries-of-mild-chronic-obstructive-pulmonary-disease-copd-design-of-the-searching-clinical-copd-onset-soon-study
#7
Gonzalo Labarca, Andrea Bustamante, Gonzalo Valdivia, Rodrigo Díaz, Álvaro Huete, Paul Mac Nab, Laura Mendoza, Jaime Leppe, Carmen Lisboa, Fernando Saldías, Orlando Díaz
INTRODUCTION: Clinical onset of chronic obstructive pulmonary disease (COPD) is the point at which the disease is first identifiable by physicians. It is a poorly defined stage which seems to include both mild spirometric and non-spirometric disease, and could be described as early grade COPD, for practical purposes. While dyspnoea; chronic bronchitis and CT imaging evidence of emphysema and airway disease may be present very early, the lone significance of dyspnoea, the most relevant symptom in COPD in identifying these individuals, has been scarcely assessed...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28800177/exercise-stress-test-reveals-ineligibility-for-subcutaneous-implantable-cardioverter-defibrillator-in-patients-with-brugada-syndrome
#8
Motomi Tachibana, Nobuhiro Nishii, Hiroshi Morita, Koji Nakagawa, Atsuyuki Watanabe, Kazufumi Nakamura, Hiroshi Ito
BACKGROUND: The eligibility of patients with Brugada syndrome (BrS) for implantation of a subcutaneous implantable cardioverter defibrillator (S-ICD) is not well known. This study aimed to clarify the eligibility of BrS patients for S-ICD using electrocardiography (ECG) at rest and during exercise testing. We also analyzed factors associated with ineligibility for S-ICD from standard 12-lead ECG at rest. METHODS: We enrolled 110 consecutive BrS patients who visited Okayama university hospital from December 2015 to December 2016...
August 11, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28796094/patulous-eustachian-tube-dysfunction-patient-demographics-and-comorbidities
#9
Bryan K Ward, Yehia Ashry, Dennis S Poe
OBJECTIVE: The objective is to describe a large cohort of patients presenting with patulous Eustachian tube (pET) dysfunction. STUDY DESIGN: Retrospective patient series. SETTING: Tertiary referral center. PATIENTS: All outpatient visits (2004-2016) that were assigned ICD9 code (381.7-Patulous Eustachian tube) were screened. Only patients with observed tympanic membrane movements during ipsilateral nasal breathing or acoustic reflex decay testing demonstrating transmitted nasal breathing were included (n = 190, n = 239 ears)...
August 8, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28794903/a-novel-plant-based-sea-water-culture-media-for-in-vitro-cultivation-and-in-situ-recovery-of-the-halophyte-microbiome
#10
Mohamed Y Saleh, Mohamed S Sarhan, Elhussein F Mourad, Mervat A Hamza, Mohamed T Abbas, Amal A Othman, Hanan H Youssef, Ahmed T Morsi, Gehan H Youssef, Mahmoud El-Tahan, Wafaa A Amer, Mohamed Fayez, Silke Ruppel, Nabil A Hegazi
The plant-based-sea water culture medium is introduced to in vitro cultivation and in situ recovery of the microbiome of halophytes. The ice plant (Mesembryanthemum crystallinum) was used, in the form of juice and/or dehydrated plant powder packed in teabags, to supplement the natural sea water. The resulting culture medium enjoys the combinations of plant materials as rich source of nutrients and sea water exercising the required salt stress. As such without any supplements, the culture medium was sufficient and efficient to support very good in vitro growth of halotolerant bacteria...
November 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28792995/-attention-to-elderly-individuals-with-hypertension-the-brazilian-national-health-survey-2013
#11
Rosália Garcia Neves, Suele Manjourany Silva Duro, Thaynã Ramos Flores, Bruno Pereira Nunes, Caroline Dos Santos Costa, Andrea Wendt, Fernando César Wehrmeister, Elaine Tomasi
This study aimed to assess the attention paid by health professionals to elderly individuals with hypertension and related inequalities in Brazil, using level of schooling as the socioeconomic indicator. This was a cross-sectional study with data from the Brazilian National Health Survey, 2013. Attention was assessed according to the following indicators: recommendations for healthy eating, maintaining adequate weight, less salt, regular exercise, prevention of smoking and excessive drinking, and regular medical checkups with blood and urine tests, ECG, and stress test...
August 7, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28789970/mitochondrial-fusion-fission-and-mitochondrial-toxicity
#12
Joel N Meyer, Tess C Leuthner, Anthony L Luz
Mitochondrial dynamics are regulated by two sets of opposed processes: mitochondrial fusion and fission, and mitochondrial biogenesis and degradation (including mitophagy), as well as processes such as intracellular transport. These processes maintain mitochondrial homeostasis, regulate mitochondrial form, volume and function, and are increasingly understood to be critical components of the cellular stress response. Mitochondrial dynamics vary based on developmental stage and age, cell type, environmental factors, and genetic background...
August 5, 2017: Toxicology
https://www.readbyqxmd.com/read/28789916/flecainide-reduces-ventricular-arrhythmias-in-patients-with-genotype-ryr2-positive-catecholaminergic-polymorphic-ventricular-tachycardia
#13
Fernando Wangüemert Pérez, Julio Salvador Hernández Afonso, María Del Val Groba Marco, Eduardo Caballero Dorta, Luis Álvarez Acosta, Oscar Campuzano Larrea, Guillermo Pérez, Josep Brugada Terradellas, Ramón Brugada Terradellas
INTRODUCTION AND OBJECTIVES: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited disease characterized by polymorphic or bidirectional ventricular arrhythmias (VA) triggered by physical or emotional stress in young people with a structurally normal heart. Beta-blockers are the cornerstone of treatment, while flecainide has recently been incorporated into the therapeutic arsenal. The aim of this study was to report our experience with this drug. METHODS: The cohort included 174 genotype-positive CPVT-patients from 7 families...
August 5, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28782599/ascertainment-of-unmet-needs-and-participation-in-health-maintenance-and-screening-of-adult-hematopoietic-cell-transplantation-hct-survivors-followed-in-a-formal-survivorship-program
#14
Theresa Hahn, Pamela Paplham, Tammy Austin-Ketch, Yali Zhang, Jennifer Grimmer, Michael Burns, Sophia Balderman, Maureen Ross, Philip L McCarthy
This study aimed to ascertain unmet needs in autologous and allogeneic HCT recipients actively followed in an established long-term survivorship clinic at Roswell Park Cancer Institute from 2006-2012. The Survivor Unmet Needs Survey (SUNS) was mailed to 209 eligible patients and returned by 110 (53% participation rate). SUNS includes 89-items covering 5 domains: Emotional Health, Access and Continuity of Care, Relationships, Financial Concerns, and Information. The top five specific unmet needs for autologous HCT patients were: inability to set future goals/long-term plans; changes in appearance; bad memory/lacking focus; losing confidence in abilities; paying household or other bills...
August 4, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28780660/update-on-valvular-heart-disease-in-pregnancy
#15
REVIEW
Lucy M Safi, Sarah V Tsiaras
Valvular heart disease in women of childbearing age poses an increased risk of adverse maternal and fetal outcomes, and management in pregnancy can be challenging. Ideally, patients with suspected valvular disease should have preconception counseling by a multidisciplinary team including cardiologists with expertise in pregnancy and a maternal-fetal medicine specialist. Preconception planning should include a cardiac assessment of maternal risk, determination of frequency of surveillance, and a cardiovascular management plan during delivery...
September 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28770819/a-systematic-review-and-meta-analysis-of-exercise-and-exercise-hypertension-in-patients-with-aortic-coarctation
#16
REVIEW
H J A Foulds, N B Giacomantonio, S S D Bredin, D E R Warburton
Exercise hypertension is a common occurrence among individuals with aortic coarctation. Although exercise is known to be beneficial among the general population, the risks and benefits of exercise among those with aortic coarctation are less clear. This systematic review evaluates the benefits and risks of exercise for persons with aortic coarctation. Electronic databases were systematically searched (that is, MEDLINE and EMBASE) and key reviews cross-referenced to identify articles for inclusion. Original research articles reporting exercise among individuals with aortic coarctation were included...
August 3, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28770457/exercise-induced-polymorphic-ventricular-tachycardia-during-treadmill-stress-test
#17
Federico G De Puy, Ayman A Farag, Vineet Kumar
No abstract text is available yet for this article.
August 2, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28768468/predictive-value-of-exercise-induced-atrial-natriuretic-peptide-secretion-for-the-presence-of-left-atrial-low-voltage-areas-in-patients-with-persistent-atrial-fibrillation
#18
Ran Yin, Zhongming Yang, Jingtian Peng, Bingong Li, Yongnan Fu, Zheqi Zheng
Objectives Left atrial (LA) low-voltage areas (LVAs) are a strong predictor of atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI). However, a non-invasive method for evaluating LA-LAVs has not been established yet. The objective of our study was to assess the predictive value of the plasma atrial natriuretic peptide (ANP) level for the presence of LA-LVAs in patients with persistent AF (PeAF). Methods Seventy-two PeAF patients underwent an exercise stress test preprocedurally. LA voltage maps were created after PVI...
August 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28766183/guided-imagery-targeting-exercise-food-cravings-and-stress-a-multi-modal-randomized-feasibility-trial
#19
Peter Giacobbi, Dustin Long, Richard Nolan, Samantha Shawley, Kelsey Johnson, Ranjita Misra
The purpose of this randomized wait-list controlled trial was to test the feasibility and preliminary efficacy of a guided imagery based multi-behavior intervention intended to address psychological stress, food cravings, and physical activity. Personalized guided imagery scripts were created and participants were instructed to practice guided imagery every day for 35 consecutive days. Of 48 women who enrolled, we report comparisons between 16 randomized to treatment with 19 who were wait-listed (overall Mage = 45...
August 1, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28762914/-adaptation-to-intermittent-hypoxia-hyperoxia-in-the-rehabilitation-of-patients-with-ischemic-heart-disease-exercise-tolerance-and-quality-of-life
#20
A L Syrkin, O S Glazachev, F Y Kopylov, E N Dudnik, E E Zagaynaya, D S Tuter
AIM: to assess effect of interval hypoxic-hyperoxic training (IT) on exercise tolerance and quality of life of patients with ischemic heart disease (IHD) receiving optimal medical therapy, as well as the safety of IHHT use. METHODS: Patients with stable IHD with functional class II and III angina (n=46) were randomized into two groups: IHHT (n=27, 15 treatments in 3 weeks), and IHHT imitation (n=19). Cardiopulmonary stress test was performed to evaluate the following parameters of exercise tolerance: peak oxygen consumption (VO2peak, VO2peak/kg), % of predicted peak oxygen consumption (%VO2 peak) and anaerobic threshold (VO2AT)...
May 2017: Kardiologiia
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