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https://www.readbyqxmd.com/read/28925651/exercise-stress-testing-indications-and-common-questions
#1
Kathryn K Garner, William Pomeroy, James J Arnold
Exercise stress testing is a validated diagnostic test for coronary artery disease in symptomatic patients, and is used in the evaluation of patients with known cardiac disease. Testing of asymptomatic patients is generally not indicated. It may be performed in select deconditioned adults before starting a vigorous exercise program, but no studies have compared outcomes from preexercise testing vs. encouraging light exercise with gradual increases in exertion. Preoperative exercise stress testing is helpful for risk stratification in patients undergoing vascular surgery or who have active cardiac symptoms before undergoing nonemergent noncardiac surgery...
September 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28924977/performing-lung-ultrasound-at-rest-and-or-after-an-exercise-stress-test-to-better-identify-high-risk-ambulatory-patients-with-heart-failure
#2
EDITORIAL
Nicolas Girerd, Patrick Rossignol
No abstract text is available yet for this article.
September 18, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28923457/blood-flow-regulation-and-oxidative-stress-during-submaximal-cycling-exercise-in-patients-with-cystic-fibrosis
#3
Matthew A Tucker, Breana Berry, Nichole Seigler, Gareth W Davison, John C Quindry, Dabney Eidson, Kathleen T McKie, Ryan A Harris
BACKGROUND: The impact of blood flow regulation and oxidative stress during exercise in cystic fibrosis (CF) has yet to be investigated. METHODS: A maximal graded exercise test was conducted to determine exercise capacity (VO2 peak) and peak workload in 14 pediatric patients with mild CF (age 14±3y, FEV1 93±16 % predicted) and 14 demographically-matched controls. On a separate visit, participants performed submaximal cycling up to 60% of peak workload where brachial artery blood velocity was determined using Doppler ultrasound...
September 8, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28921674/decline-in-effort-capacity-with-age-echocardiographic-stress-analysis-in-the-elderly
#4
Anat Milman, Gad Keren, Yan Topilsky
BACKGROUND: The present study was designed to assess the underlying mechanism of decline in effort capacity seen with aging. METHODS: We analyzed 250 healthy senior patients (≥65 years) with an ejection fraction ≥60% who underwent a stress echocardiogram test. The seniors (aged 65-94) were divided into 3 equal age groups (groups 1, 2, and 3), and their echo characteristics at rest and peak exercise (measured and calculated) were compared. RESULTS: Diastolic function at rest declined significantly (E lateral, E septal, E/E', A) with age, while other rest parameters were similar...
September 17, 2017: Echocardiography
https://www.readbyqxmd.com/read/28915226/pulmonary-vascular-function-and-aerobic-exercise-capacity-at-moderate-altitude
#5
Vitalie Faoro, Gael Deboeck, Marco Vicenzi, Anne-Fleur Gaston, Bamodi Simaga, Grégory Doucende, Ilona Hapkova, Emma Roca, Enric Subirats, Fabienne Durand, Robert Naeije
PURPOSE: There has been suggestion that a greater "pulmonary vascular reserve" defined by a low pulmonary vascular resistance (PVR) and a high lung diffusing capacity (DL) allow for a superior aerobic exercise capacity. How pulmonary vascular reserve might affect exercise capacity at moderate altitude is not known. METHODS: Thirty-eight healthy subjects underwent an exercise stress echocardiography of the pulmonary circulation, combined with measurements of DL for nitric oxide (NO) and carbon monoxide (CO) and a cardiopulmonary exercise test at sea level and at an altitude of 2250 m...
October 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28895507/functional-impact-of-exercise-pulmonary-hypertension-in-patients-with-borderline-resting-pulmonary-arterial-pressure
#6
Rudolf K F Oliveira, Mariana Faria-Urbina, Bradley A Maron, Mario Santos, Aaron B Waxman, David M Systrom
Borderline resting mean pulmonary arterial pressure (mPAP) is associated with adverse outcomes and affects the exercise pulmonary vascular response. However, the pathophysiological mechanisms underlying exertional intolerance in borderline mPAP remain incompletely characterized. In the current study, we sought to evaluate the prevalence and functional impact of exercise pulmonary hypertension (ePH) across a spectrum of resting mPAP's in consecutive patients with contemporary resting right heart catheterization (RHC) and invasive cardiopulmonary exercise testing...
July 2017: Pulmonary Circulation
https://www.readbyqxmd.com/read/28890527/microvascular-angina%C3%A3-long-term-exercise-stress-test-follow-up
#7
Gaetano A Lanza, Monica Filice, Antonio De Vita, Angelo Villano, Laura Manfredonia, Priscilla Lamendola, Filippo Crea
BACKGROUND: A sizeable proportion of patients with primary stable microvascular angina (MVA; exercise-induced angina, positive exercise stress test [EST], normal coronary arteries) have recurrent symptoms during follow-up. There have been no previous studies, however, on the long-term results of EST and their correlation with symptom outcome.Methods and Results:Follow-up EST was performed in 71 MVA patients at an average of 16.2 years (range, 5-25 years) from the first EST. Angina status was assessed on weekly frequency of angina episodes and nitroglycerin consumption and by whether symptoms had worsened, improved, or remained unchanged over time...
September 9, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28888894/exercise-intervention-attenuates-hyperhomocysteinemia-induced-aortic-endothelial-oxidative-injury-by-regulating-sirt1-through-mitigating-nadph-oxidase-lox-1-signaling
#8
Shih-Hung Chan, Ching-Hsia Hung, Jhih-Yuan Shih, Pei-Ming Chu, Yung-Hsin Cheng, Huei-Chen Lin, Pei-Ling Hsieh, Kun-Ling Tsai
Coronary artery disease (CAD) is a critical cardiovascular disease and a cause of high morbidity and mortality in this world. Hyperhomocysteinemia (HHcy) has been suggested as a risk factor for CAD. In addition, SIRT1 (sirtuin 1) has been reported to play a protective role in a variety of diseases, especially in the cardiovascular system. The main purpose of this study was to investigate the effects of exercise training on apoptosis and inflammation in HHcy animals. We also tested whether exercise protected against Hhcy-induced dysfunction of endothelium through modulation of SIRT1...
August 24, 2017: Redox Biology
https://www.readbyqxmd.com/read/28887315/inorganic-nitrate-in-angina-study-a-randomized-double-blind-placebo-controlled-trial
#9
Konstantin Schwarz, Satnam Singh, Satish K Parasuraman, Amelia Rudd, Lee Shepstone, Martin Feelisch, Magdalena Minnion, Shakil Ahmad, Melanie Madhani, John Horowitz, Dana K Dawson, Michael P Frenneaux
BACKGROUND: In this double-blind randomized placebo-controlled crossover trial, we investigated whether oral sodium nitrate, when added to existing background medication, reduces exertional ischemia in patients with angina. METHODS AND RESULTS: Seventy patients with stable angina, positive electrocardiogram treadmill test, and either angiographic or functional test evidence of significant ischemic heart disease were randomized to receive oral treatment with either placebo or sodium nitrate (600 mg; 7 mmol) for 7 to 10 days, followed by a 2-week washout period before crossing over to the other treatment (n=34 placebo-nitrate, n=36 nitrate-placebo)...
September 8, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28885930/therapeutic-lifestyle-changes-impact-on-weight-quality-of-life-and-psychiatric-symptoms-in-veterans-with-mental-illness
#10
Jillian M Tessier, Zachary D Erickson, Hilary B Meyer, Matthew R Baker, Hollie A Gelberg, Irina Y Arnold, Crystal Kwan, Valery Chamberlin, Jennifer A Rosen, Chandresh Shah, Gerhard Hellemann, Melissa M Lewis, Charles Nguyen, Neena Sachinvala, Binyamin Amrami, Joseph M Pierre, Donna Ames
INTRODUCTION: Veterans with mental illness tend to have shorter life spans and suboptimal physical health because of a variety of factors. These factors include poor nutrition, being overweight, and smoking cigarettes. Nonphysical contributors that may affect quality of life are the stigma associated with mental illness, social difficulties, and spiritual crises. Current mental health treatment focuses primarily on the delivery of medication and evidence-based psychotherapies, which may not affect all the above areas of a Veteran's life as they focus primarily on improving psychological symptoms...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28882941/anomalous-left-anterior-descending-artery-arising-from-the-pulmonary-trunk-a-rare-cause-of-angina
#11
Abdalla Ibrahim, Stephen P Power, Peter Kelly
A 60-year-old man with a medical history of hypertension and dyslipidaemia presented to our rapid access chest pain clinic with a 2-month history of chest pain on exertion. An exercise stress test was arranged, which showed electrical evidence of inducible ischaemia. Subsequently, a coronary angiogram revealed an anomalous left anterior descending artery arising from the main pulmonary artery that received grade 3 collaterals from a large right coronary artery arising from the aorta. The circumflex arises from the right coronary sinus with a retroaortic course and provided collaterals to the anomalous left anterior descending artery...
September 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28882773/shockwave-treatment-for-medial-tibial-stress-syndrome-in-military-cadets-a-single-blind-randomized-controlled-trial
#12
Santiago Gomez Garcia, Silvia Ramon Rona, Martha Claudia Gomez Tinoco, Mikhail Benet Rodriguez, Diego Mauricio Chaustre Ruiz, Francia Piedad Cardenas Letrado, África Lopez-Illescas Ruiz, Juan Maria Alarcon Garcia
Medial tibial stress syndrome (MTSS) is a common injury in athletes and soldiers. Several studies have demonstrated the effectiveness of extracorporeal shockwave treatment (ESWT) in athletes with MTSS. OBJECTIVE: To assess whether one session of focused ESWT is effective in the treatment of military cadets with MTSS. DESIGN: A randomized, prospective, controlled, single-blind, parallel-group clinical study. LEVEL OF EVIDENCE: Ib. SETTING: Military School of Cadets of the Colombian Army...
September 5, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28878952/pathophysiology-of-exercise-intolerance-in-chronic-diseases-the-role-of-diminished-cardiac-performance-in-mitochondrial-and-heart-failure-patients
#13
Jodi McCoy, Matthew Bates, Christopher Eggett, Mario Siervo, Sophie Cassidy, Jane Newman, Sarah A Moore, Grainne Gorman, Michael I Trenell, Lazar Velicki, Petar M Seferovic, John G F Cleland, Guy A MacGowan, Doug M Turnbull, Djordje G Jakovljevic
OBJECTIVE: Exercise intolerance is a clinical hallmark of chronic conditions. The present study determined pathophysiological mechanisms of exercise intolerance in cardiovascular, neuromuscular, and metabolic disorders. METHODS: In a prospective cross-sectional observational study 152 patients (heart failure reduced ejection fraction, n=32; stroke, n=34; mitochondrial disease, n=28; type two diabetes, n=28; and healthy controls, n=30) performed cardiopulmonary exercise testing with metabolic and haemodynamic measurements...
2017: Open Heart
https://www.readbyqxmd.com/read/28876372/functional-capacity-in-congenital-heart-disease-a-systematic-review-and-meta-analysis
#14
Camila Wohlgemuth Schaan, Aline Chagastelles Pinto de Macedo, Graciele Sbruzzi, Daniel Umpierre, Beatriz D Schaan, Lucia Campos Pellanda
BACKGROUND: Children and adolescents with congenital heart disease often have alterations in their exercise capacity that can be evaluated by various functional testing. OBJECTIVE: To evaluate the functional capacity of children and adolescents with congenital heart disease (CHD) with systematic review and meta-analyses. METHODS: The review included observational studies, data from the first evaluation of randomized clinical trials or observational follow-up periods after clinical trials which evaluated functional capacity by cardiopulmonary exercise test, stress testing, six-minute walk test or step test, in children and adolescents with CHD, aged between six and 18 years, and comparisons with healthy controls in the same age group...
September 4, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28873397/long-term-intra-individual-reproducibility-of-heart-rate-dynamics-during-exercise-and-recovery-in-the-uk-biobank-cohort
#15
Michele Orini, Andrew Tinker, Patricia B Munroe, Pier D Lambiase
BACKGROUND: The heart rate (HR) response to exercise provides useful information about the autonomic function and has prognostic value, but its reproducibility over a long period of time, a critical requirement for using it as a clinical biomarker, is undetermined. AIM: To determine the intra-individual reproducibility of HR dynamics during sub-maximum exercise and one minute recovery. METHODS: 1187 individuals from the Cardio physical fitness assessment test of the UK Biobank repeated a standard exercise stress test twice (recall time 34...
2017: PloS One
https://www.readbyqxmd.com/read/28873320/influence-of-rhodiola-rosea-on-the-heat-acclimation-process-in-young-healthy-men
#16
Saima Timpmann, Anthony C Hackney, Maria Tamm, Kairi Kreegipuu, Eve Unt, Vahur Ööpik
The adaptogen <i>Rhodiola rosea</i> (RR) may mitigate stress responses and have beneficial effects on endurance capacity (EC) and mental performance. Heat acclimation (HA) improves EC in the heat, but the potential impact of RR on the HA process is unknown. Therefore, our intent was to determine would RR impact positively on the efficacy of the HA process. Twenty male subjects (age 22.5 ± 3.0 years) completed two EC tests involving walking (6 km·h <sup>-1</sup>) until volitional exhaustion in a climate chamber (air temperature, 42°C; relative humidity, 18%) before (H1) and after (H2) an 8-day HA period...
September 5, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28871440/triheptanoin-versus-trioctanoin-for-long-chain-fatty-acid-oxidation-disorders-a-double-blinded-randomized-controlled-trial
#17
Melanie B Gillingham, Stephen B Heitner, Julie Martin, Sarah Rose, Amy Goldstein, Areeg Hassan El-Gharbawy, Stephanie Deward, Michael R Lasarev, Jim Pollaro, James P DeLany, Luke J Burchill, Bret Goodpaster, James Shoemaker, Dietrich Matern, Cary O Harding, Jerry Vockley
BACKGROUND: Observational reports suggest that supplementation that increases citric acid cycle intermediates via anaplerosis may have therapeutic advantages over traditional medium-chain triglyceride (MCT) treatment of long-chain fatty acid oxidation disorders (LC-FAODs) but controlled trials have not been reported. The goal of our study was to compare the effects of triheptanoin (C7), an anaplerotic seven-carbon fatty acid triglyceride, to trioctanoin (C8), an eight-carbon fatty acid triglyceride, in patients with LC-FAODs...
September 4, 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/28861743/feasibility-and-safety-of-exercise-stress-testing-using-an-anti-gravity-treadmill-with-tc-99m-tetrofosmin-single-photon-emission-computed-tomography-spect-myocardial-perfusion-imaging-a-pilot-non-randomized-controlled-study
#18
Patrick Daly, Regina Kayse, Steven Rudick, Nathan Robbins, Jennifer Scheler, David Harris, Robert O'Donnell, Alok K Dwivedi, Myron C Gerson
BACKGROUND: Exercise is the AHA/ACC guideline-recommended stress modality for myocardial perfusion imaging, but many patients are unable to exercise to target heart rate on a conventional treadmill. We examined the feasibility and safety of stress imaging using an anti-gravity treadmill in patients with perceived poor exercise capacity. METHODS AND RESULTS: 49 patients were recruited for stress testing by anti-gravity treadmill (n = 29) or to a regadenoson control group (n = 20)...
August 31, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28859898/the-effect-of-dietary-antioxidants-and-exercise-training-on-the-escape-performance-of-southern-corroboree-frogs
#19
Emma P McInerney, Phillip G Byrne, Aimee J Silla
Escape-response behaviour is essential to ensure an individual's survival during a predator attack, however, these behaviours are energetically costly and may cause oxidative stress. Oxidative stress can be reduced by supplementing an individual's diet with exogenous antioxidants or through regular moderate exercise training, which stimulates the upregulation of the endogenous antioxidant system. Two studies have tested the simultaneous effects of dietary antioxidant supplementation and exercise training on animal escape-response behaviour...
August 30, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28859527/unique-relations-between-post-traumatic-stress-disorder-symptoms-and-patient-functioning-in-type-2-diabetes
#20
Danielle Arigo, Vanessa Juth, Paula Trief, Kenneth Wallston, Jan Ulbrecht, Joshua M Smyth
This study examined reported post-traumatic stress disorder symptoms in adults with poorly controlled type 2 diabetes who had no history of psychiatric diagnosis or treatment ( n = 184, MHbA1c = 9.13%, standard deviation = 1.68). Participants reported moderate to severe intensity of post-traumatic stress disorder symptoms ( M = 19.17, SD = 17.58). Together, depressive and post-traumatic stress disorder symptoms accounted for 10-40 percent of the variance in type 2 diabetes outcomes; post-traumatic stress disorder symptoms were associated with elevated diabetes distress and more frequent exercise and self-blood glucose testing (unique R(2) ~ 3%)...
August 1, 2017: Journal of Health Psychology
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