keyword
https://read.qxmd.com/read/38520630/copper-deficiency-anemia-due-to-zinc-supplementation-in-a-chronic-hemodialysis-patient
#1
JOURNAL ARTICLE
Tomoka Watanabe, Satomi Yonemoto, Yoshihiro Ikeda, Kiyotaka Kawaguchi, Tatsuo Tsukamoto
Zinc deficiency causes dysgeusia and dermatitis as well as anemia. As approximately half of dialysis patients have zinc deficiency, zinc supplementation should be considered in case of erythropoiesis-stimulating agent (ESA)-hyporesponsive anemia. We report a case of a chronic dialysis patient with copper deficiency anemia caused by standard-dose zinc supplementation. The patient was a 70-year-old woman who had received maintenance hemodialysis for 8 years due to diabetic nephropathy. She had been treated with weekly administration of darbepoetin 30 μg for renal anemia, which resulted in Hb 12 to 14 g/dL...
March 23, 2024: CEN Case Reports
https://read.qxmd.com/read/38489867/growth-hormone-treatment-in-aged-patients-with-comorbidities-a-systematic-review
#2
REVIEW
Olivia Tausendfreund, Martin Bidlingmaier, Sebastian Martini, Katharina Müller, Michaela Rippl, Katharina Schilbach, Ralf Schmidmaier, Michael Drey
OBJECTIVE: Hormonal substitution with growth hormone in aged patients remains a debated research topic and is rarely initiated in clinical practice. This reluctance may originate from concerns about adverse effects and the uncritical use as an anti-aging agent. Nevertheless, beneficial effects for selected patients suffering from certain acute and chronic illnesses could justify its use at an advanced age. This systematic review analyzes randomized controlled studies of GH interventions in older patients with different comorbidities to assess both, beneficial and harmful effects...
March 9, 2024: Growth Hormone & IGF Research
https://read.qxmd.com/read/38486685/sudan-s-healthcare-crisis-the-struggle-of-kidney-patients-amidst-conflict
#3
JOURNAL ARTICLE
Emadeldin Hassan E Konozy
BACKGROUND AND AIM: Conflicts, akin to other crises, disrupt lives and healthcare infrastructure, disproportionately affecting vulnerable individuals. The ongoing Sudanese conflict, initiated on April 15, 2023, between the Sudanese Armed Forces (SAF) and the Rapid Support Force (RSF), triggers significant population displacement, healthcare facility closures, and a scarcity of medical resources. Amid the intense conflict in Khartoum, reports of deceased individuals in the streets heighten concerns about public health, emphasizing the gravity of the situation...
March 2024: Health Science Reports
https://read.qxmd.com/read/38481490/providing-hemodialysis-in-unstable-areas-an-assessment-and-framework-for-effective-care
#4
JOURNAL ARTICLE
Sami Alasfar, Hani Alashavi, Khaled Hajj Nasan, Abd Aljabbar Haj Mousa, Camila Polinori, Valerie Luyckx, Mohamed Sekkarie, Saleh Kaysi, Lina Murad, Gilbert M Burnham
INTRODUCTION: Providing hemodialysis to patients with kidney failure (KF) in conflict-affected areas poses a significant challenge. Achieving and sustaining reasonable quality hemodialysis operations in such regions necessitates a comprehensive approach. METHODS: In the conflict area of Northwest (NW) Syria, a 3-phase project was initiated to address the quality of hemodialysis operations. The assessment phase involved the examination of infection prevention and control (IPC) protocols, staff training, medical protocols, individualized hemodialysis prescriptions, and laboratory testing capabilities...
March 2024: KI Reports
https://read.qxmd.com/read/38468417/treatment-of-severe-hyponatremia-with-continuous-renal-replacement-therapy-a-case-and-review-of-corrective-strategies
#5
Paul J Der Mesropian, Shawn Phillips, Martha Naber, Sunjeev Konduru, Gulvahid Shaikh, Krishnakumar Hongalgi
Treatment of severely hyponatremic patients with continuous renal replacement therapy (CRRT) presents a unique challenge given the lack of commercial options for hypotonic replacement solutions or dialysate. We report the case of a 55-year-old male who presented with profound, symptomatic hyponatremia in the setting of acute kidney injury (AKI). The patient was found to have a serum sodium concentration of 97 mEq/L because of free water retention that occurred during severe AKI from viral gastroenteritis and rhabdomyolysis...
March 11, 2024: Hemodialysis International
https://read.qxmd.com/read/38464414/the-effects-of-omega-3-fatty-acids-supplementation-on-hemoglobin-hematocrit-and-platelet-levels-of-patients-with-esrd-condition-undergoing-dialysis
#6
JOURNAL ARTICLE
Zahra Mahmoudi, Zahra Roumi, Seyed Ali Askarpour, Zahra Mousavi, Hanieh Shafaei, Neda Valisoltani, Mahsa Shapouri, Seyed Reza Mirshafaei, Pouya Mirzaee, Khadijeh Abbasi Mobarakeh, Elahe Taghavi Sufiani, Zeinab Motiee Bijarpasi, Zeynab Motiei, Masoud Khosravi, Saeid Doaei, Maryam Gholamalizadeh
BACKGROUND: Concomitant inflammation may boost the cardiovascular complications in end-stage renal disease (ESRD) patients undergoing hemodialysis (HD). Omega-3 fatty acids may have certain health benefits in HD patients. The aim of this study was to investigate the effects of omega-3 fatty acids supplementation on hematocrit (HCT), hemoglobin (HB) level and platelet (PLT) counts of HD patients. METHODS: A randomized controlled trial was conducted on HD patients at a private dialysis center in Rasht, Iran...
June 2024: Journal of translational autoimmunity
https://read.qxmd.com/read/38453435/efficacy-tolerability-and-safety-of-the-oral-phosphate-binder-vs-505-ap301
#7
JOURNAL ARTICLE
Bing Zhuang, Liangying Gan, Bin Liu, Weijie Yuan, Ming Shi, Ai Peng, Lihua Wang, Xiaolan Chen, Tongqiang Liu, Shiying Zhang, Song Wang, Qing Gao, Baoxing Wang, Huixiao Zheng, Changhua Liu, Yuan Luo, Hong Ye, Hongli Lin, Yiwen Li, Qiang He, Feng Zheng, Ping Luo, Gang Long, Wei Lu, Kanghui Li, Junwei Yang, Yingxue Cathy Liu, Zhizheng Zhang, Xiaolin Li, Weifeng Zhang, Li Zuo
BACKGROUND: VS-505 (AP301), an acacia and ferric oxyhydroxide polymer, is a novel fiber-iron-based phosphate binder. This two-part phase 2 study evaluated the tolerability, safety, and efficacy of oral VS-505 administered three times daily with meals in treating hyperphosphatemia in chronic kidney disease (CKD) patients receiving maintenance hemodialysis (MHD). METHODS: In Part 1, patients received dose-escalated treatment with VS-505 2.25, 4.50, and 9.00 g/day for 2 weeks each, guided by serum phosphorus levels...
March 7, 2024: Nephrology, Dialysis, Transplantation
https://read.qxmd.com/read/38421519/oritavancin-versus-daptomycin-for-osteomyelitis-treatment-after-surgical-debridement
#8
JOURNAL ARTICLE
Nicholas W Van Hise, Russell M Petrak, Kairav Shah, Melina Diaz, Vishnu Chundi, Mark Redell
INTRODUCTION: Weekly intravenous (IV) oritavancin and daily daptomycin were compared in an outpatient setting following extensive surgical debridement for treating patients with osteomyelitis. METHODS: This was a retrospective, observational study of patients diagnosed with acute osteomyelitis. Exclusion criteria were the use of Gram-negative antibiotic therapy, use of antibiotics for more than 48 h prior to oritavancin or daptomycin or prior use of > 2 doses of oritavancin or more than 4 weeks of daptomycin...
February 29, 2024: Infectious Diseases and Therapy
https://read.qxmd.com/read/38413859/subjectivity-study-on-health-conservation-of-elderly-hemodialysis-patients
#9
JOURNAL ARTICLE
Eunji Yim, Mijin Yun, Sohyune Sok
BACKGROUND: Health conservation enables elderly hemodialysis patients to maintain a positive state of well-being while undergoing treatment and maintenance of disease. This study was to identify the type of perceptions on health conservation of elderly hemodialysis patients and compare the characteristics of perceptions. METHODS: This study used an exploratory study design applying Q methodology, which is designed to research subjectivity. The study determined a population of subjective statements, the concourse, based on the preceding literature and interviews with twenty-five elderly patients over 65 years of age with hemodialysis...
February 27, 2024: BMC Geriatrics
https://read.qxmd.com/read/38402748/plasma-sodium-during-the-recovery-of-renal-function-in-critically-ill-adult-patients-multicenter-prospective-cohort-study
#10
JOURNAL ARTICLE
Natalia Alejandra Angeloni, Irene Outi, Monica Alejandra Alvarez, Sofia Sterman, Julio Fernandez Morales, Fabio Daniel Masevicius
BACKGROUND: Sodium increases during acute kidney injury (AKI) recovery. Both hypernatremia and positive fluid balances are associated with increased mortality. We aimed to evaluate the association between daily fluid balance and daily plasma sodium during the recovery from AKI among critical patients. METHODS: Adult patients with AKI were enrolled in four ICUs and followed up for four days or until ICU discharge or hemodialysis initiation. Day zero was the peak day of creatinine...
February 24, 2024: Journal of Critical Care
https://read.qxmd.com/read/38402498/a-survey-of-environmental-sustainability-in-japanese-dialysis-facilities
#11
JOURNAL ARTICLE
Kei Nagai, Katherine Barraclough, Nanae Matsuo, Atsushi Ueda, Tsutomu Kuno, Kanji Shishido, Yutaka Koda
BACKGROUND: Dialysis practice has a particularly high environmental impact, including responsible for carbon emissions and climate change. Insufficient research has been conducted on environmental sustainability activities in dialysis therapy in Japan. METHODS: We conducted an online Green Survey comprising 30 question items based on a previously conducted survey in Australia. Between August and September 2023, this was sent to members of the Japanese Association of Dialysis Physicians, including hospital and clinic physicians, working across 885 dialysis facilities in Japan...
February 25, 2024: Clinical and Experimental Nephrology
https://read.qxmd.com/read/38379641/case-report-thrombotic-thrombocytopenic-purpura-in-a-pregnant-woman-with-lupus-membranous-nephropathy-a-diagnostic-challenge
#12
Marina Leiva, Gustavo Navarro, J Daniel Carpio, Leopoldo Ardiles
A 27-year-old female at 20th week of pregnancy was admitted with edema, foamy urine, but normal blood pressure. Her blood count was normal, she had proteinuria of 3 g/day, creatinine 0.4 mg/dl, albumin 2.4 g/dl, and cholesterol 355 mg/dl. Antinuclear antibodies 1/160, but Anti-DNA, anticardiolipin antibodies and lupus anticoagulant were negative, with normal serum C3 and C4. A renal biopsy showed secondary membranous glomerulopathy, most likely lupus class V pure. Steroids, azathioprine, and aspirin were initiated, up to 28 weeks of pregnancy, when she developed severe hypertension, photopsia, headache, anasarca, extensive bruising of the extremities, severe anemia, thrombocytopenia, and creatinine rose to 2...
2024: Front Nephrol
https://read.qxmd.com/read/38370951/impact-of-psychiatric-comorbidity-on-quality-of-life-and-activities-of-daily-living-among-patients-suffering-from-chronic-kidney-disease-undergoing-hemodialysis
#13
JOURNAL ARTICLE
Ekram Goyal, Alka Puria, Suprakash Chaudhary, Ajay Kumar, Richa Raj, Sidhartha Kumar
INTRODUCTION: Chronic Kidney Disease (CKD) is a debilitating illness that impairs an individual's physical and social functioning and ultimately affects the quality of life (QOL). AIM: To determine the impact of psychiatric comorbidity on QOL and activities of daily living in individuals suffering from CKD undergoing hemodialysis. MATERIALS AND METHODS: Fifty subjects suffering from CKD undergoing hemodialysis were consequently enrolled in the department of medicine...
November 2023: Industrial Psychiatry Journal
https://read.qxmd.com/read/38326286/effects-of-virtual-reality-on-pain-induced-by-arteriovenous-fistula-needle-insertion-in-patients-undergoing-hemodialysis-a-randomized-clinical-trial
#14
JOURNAL ARTICLE
Mohammad Namazinia, Samira Mohajer, Seddigheh Abbaspour, Violeta Lopez, Tahere Sarboozi-Hoseinabadi
BACKGROUND: Chronic kidney disease (CKD) is characterized by irreversible damage to renal function. For patients undergoing replacement therapies like hemodialysis (HD), the pain caused by arteriovenous fistula (AVF) cannulation becomes a significant aspect of their daily lives. This study aimed to examine the impact of virtual reality (VR) distraction techniques on the pain experienced during AVF needle insertion in patients undergoing HD. MATERIALS AND METHODS: This randomized clinical trial (RCT) recruited a total of 60 patients undergoing HD from the 9 Dey Hospital in Torbat Heydariyeh, Iran, between March and August 2022...
February 7, 2024: Journal of Vascular Access
https://read.qxmd.com/read/38310128/digital-health-interventions-to-promote-healthy-lifestyle-in-hemodialysis-patients-an-interventional-pilot-study
#15
JOURNAL ARTICLE
Wen-Yi Li, Jiang-Chou Yeh, Cheng-Chih Cheng, Su-Hua Huang, Hui-Chin Yeh, Bor-Wen Cheng, Jou-Wei Lin, Feng-Jung Yang
Low physical activity has been associated with poor prognosis in hemodialysis (HD) patients. Interventions to maintain healthy lifestyle in this population are important to reduce mortality. This study aimed to evaluate the effectiveness of digital health interventions (DHIs) for improving the physical activity and health-related quality of life (HRQoL) in HD patients. The 24-week prospective study enrolled 31 clinically stable HD patients. All participants were assigned home exercises and provided with wearable devices...
February 3, 2024: Scientific Reports
https://read.qxmd.com/read/38289295/far-infrared-stimulation-of-neiguan-acupoints-improves-heart-rate-variability-and-ameliorate-fatigue-in-hemodialysis-patients-a-randomized-trial
#16
JOURNAL ARTICLE
Ling-Yu Liao, Li-Wei Chien, Chi-Feng Liu
BACKGROUND: In 2018, 84,615 patients in Taiwan received hemodialysis, of which about 62% - 97% suffered from fatigue. Fatigue caused by hemodialysis may be mental or physical. However, the detailed mechanism remains unclear. This study aimed to evaluate whether far-infrared stimulation of the neiguan acupoint (P6) could effectively reduce fatigue and improve heart rate variability (HRV) in hemodialysis patients. METHODS: We conducted a two-arm, randomized trial in a hemodialysis center between Mar 2015 and Mar 2016...
January 29, 2024: Journal of the Chinese Medical Association: JCMA
https://read.qxmd.com/read/38281653/effect-of-egg-white-protein-alone-or-combined-with-niacin-on-nutritional-status-phosphorus-control-and-circulating-fgf-23-in-maintenance-hemodialysis-patients-a-randomized-controlled-trial
#17
JOURNAL ARTICLE
Parisa Javadian, Niloofar Nematollahi, Ehsan Ghaedi, Shahram Tahmasebian, Ebrahim Saedi
BACKGROUND: Niacin is reported to decrease phosphorus concentration in Maintenance Hemodialysis (MHD) patients. Egg white is one of the main substitutable proteins in MHD patients due to its low phosphorus content. Therefore, we aimed to evaluate the effects of combined egg white and niacin supplementation on dialysis patients' serum phosphorus and nutritional biomarkers. METHODS: In this randomized controlled clinical trial, 98 patients on MHD were randomly allocated to four groups for eight weeks: 24 g egg white (n=25), 600 g niacin daily (n=24), egg white combined with niacin (n=24), and control (n=24)...
January 26, 2024: Journal of Renal Nutrition
https://read.qxmd.com/read/38254176/spontaneous-splenic-rupture-associated-with-scrub-typhus-a-case-report
#18
JOURNAL ARTICLE
Hong Pil Hwang, Kyoung Min Kim, Hyojin Han, Jeong-Hwan Hwang
BACKGROUND: Scrub typhus, an acute febrile disease with mild to severe, life-threatening manifestations, potentially presents with a variety of complications, including pneumonia, acute respiratory distress syndrome, cardiac arrhythmias (such as atrial fibrillation), myocarditis, shock, peptic ulcer, gastrointestinal bleeding, meningitis, encephalitis, and renal failure. Of the various complications associated with scrub typhus, splenic rupture has rarely been reported, and its mechanisms are unknown...
January 22, 2024: Infectious Diseases of Poverty
https://read.qxmd.com/read/38231079/standard-of-care-plus-telmisartan-on-respiratory-failure-due-to-covid-19-star-covid-trial
#19
JOURNAL ARTICLE
Abraham E Gracia-Ramos, Gissel Y Ángeles-Durán, Iván R Flores-Gómez, Emmanuel Flores-Martínez, Tania I Valdin-Orozco, Jesús R Reyes-Peralta, César Pedraza-Hervert, Flor A Garcia-Arroyo, Antonio Cortés Ortíz, María J Pecero-Hidalgo
BACKGROUND: The potential influence of renin-angiotensin inhibitors on the severity of SARS-CoV-2 infection has been considered in preclinical and observational studies with contradictory results. Therefore, we investigated the effect of telmisartan in reducing lung injury among hospitalized COVID-19 patients. METHODS: The STAR-COVID trial was conducted as a prospective, parallel-group, randomized, open-label study involving hospitalized adult patients with severe COVID-19 (NCT04510662)...
January 17, 2024: Minerva cardiology and angiology
https://read.qxmd.com/read/38227447/resistant-hypertension-in-dialysis-epidemiology-diagnosis-and-management
#20
JOURNAL ARTICLE
Panagiotis I Georgianos, Rajiv Agarwal
Apparent treatment-resistant hypertension is defined as an elevated BP despite the use of ≥3 antihypertensive medications from different classes or the use of ≥4 antihypertensives regardless of BP levels. Among patients receiving maintenance hemodialysis or peritoneal dialysis, using this definition, the prevalence of apparent treatment-resistant hypertension is estimated to be between 18% and 42%. Owing to the lack of a rigorous assessment of some common causes of pseudoresistance, the burden of true resistant hypertension in the dialysis population remains unknown...
January 16, 2024: Journal of the American Society of Nephrology: JASN
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