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(Cutaneous metastasis) -melanoma

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https://www.readbyqxmd.com/read/28734080/transumbilical-laparoendoscopic-single-site-radical-prostatectomy-and-cystectomy-with-the-aid-of-transurethral-port-a-feasibility-study
#1
Jian Su, Qingyi Zhu, Lin Yuan, Yang Zhang, Qingling Zhang, Yunfei Wei
OBJECTIVE: Our aim was to describe the surgical technique and report early outcomes of transurethral assisted laparoendoscopic single-site radical prostatectomy (LESS-RP) and cystectomy (LESS-RC) in a single institution. MATERIALS AND METHODS: Between December 2014 and March 2016, 114 cases were performed LESS-RP and LESS-RC, including LESS-RP (n=68), LESS-RC with cutaneous ureterostomy (LESS-RC/CU) (n=38) and LESS-RC with orthotopic ileal neobladder (LESS-RC/OIN) (n=8)...
July 22, 2017: BJU International
https://www.readbyqxmd.com/read/28716437/tumor-programmed-cell-death-ligand-1-expression-correlates-with-nodal-metastasis-in-patients-with-cutaneous-squamous-cell-carcinoma-of-the-head-and-neck
#2
Juana María García-Pedrero, Pablo Martínez-Camblor, Susana Diaz-Coto, Pablo Munguia-Calzada, Aitana Vallina-Alvarez, Francisco Vazquez-Lopez, Juan Pablo Rodrigo, Jorge Santos-Juanes
BACKGROUND: Binding of tumor-expressed programmed cell death ligand 1 (PD-L1) to the programmed cell death 1 (PD-1) surface receptor blocks T-cell activation thereby leading to immune evasion. Tumor PD-L1 expression has been associated with poor outcome in a wide variety of cancers; however, data in cutaneous squamous cell carcinoma (cSCC) are scarce and conflicting. OBJECTIVE: To investigate the relationship of tumor PD-L1 expression with the clinicopathologic features and prognosis of cSCC...
July 14, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28714113/secondary-syphilis-primarily-presenting-with-multiple-nodules-on-the-scalp-case-report-and-published-work-review
#3
Fan Li, Tingting Wang, Lin Wang
Syphilis, a sexually transmitted disease caused by Treponema pallidum, manifests with a broad spectrum of clinical presentations that usually involves skin. Nodular secondary syphilis occurs rarely, and mostly manifests as disseminated papulonodules or plaques over the trunk and limbs. We report an extremely rare case of nodular secondary syphilis that primarily presented with multiple nodules on the scalp, resembling Rosai-Dorfman disease or cutaneous malignant metastasis. Immunohistochemistry confirmed T...
July 17, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28712323/management-of-cutaneous-merkel-cell-carcinoma
#4
William M Mendenhall, Christopher G Morris, Jessica M Kirwan, Robert J Amdur, Christiana Shaw, Peter T Dziegielewski
PURPOSE: To report the outcomes of patients with previously untreated cutaneous Merkel cell carcinoma (MCC) managed with curative intent. MATERIAL AND METHODS: Between December 1984 and August 2015, 59 patients with previously untreated cutaneous MCC were managed with curative intent with surgery and adjuvant radiotherapy (54 patients) or radiotherapy alone (5 patients) at the University of Florida. Primary sites included head and neck (45 patients), extremities (11 patients) and trunk (3 patients)...
July 15, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28703911/low-incidence-of-metastasis-and-recurrence-from-cutaneous-squamous-cell-carcinoma-found-in-a-uk-population-do-we-need-to-adjust-our-thinking-on-this-rare-but-potentially-fatal-event
#5
Toby G Nelson, Richard E Ashton
BACKGROUND AND METHODS: Cutaneous squamous cell carcinoma (cSCC) is the commonest skin cancer with metastatic potential, however, reported rates of metastasis varies greatly. All cases of primary cSCC on the Isle of Wight between 2005 and 2014 were identified and retrospectively followed for recurrence and/or metastasis. Primary outcome was to identify the rate of metastasis/recurrence from cSCC. Secondary outcomes included associated risk factors for metastasis/recurrence, death from cSCC, and time from diagnosis of primary cSCC to event...
July 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28700504/silent-presentation-of-multiple-metastasis-burkitt-lymphoma-in-a-child-a-case-report-and-review-of-the-literature
#6
Ingrith Miron, Lucian Miron, Vasile Valeriu Lupu, Ancuta Ignat
RATIONALE: The Burkitt lymphoma (BL) is a very aggressive B-cell non-Hodgkin's lymphoma. It accounts for 34% of lymphoma cases in children. PATIENT CONCERNS: We present the case of a 6-year-old boy diagnosed with BL, who presented multiple contrasting elements of the disease: silent symptomatology, without involvement of the bone marrow at first, but with multiorgan infiltration and a fast evolution, despite starting the treatment shortly after the symptoms appeared...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28678985/clinical-and-incidental-perineural-invasion-of-cutaneous-squamous-cell-carcinoma-a-systematic-review-and-pooled-analysis-of-outcomes-data
#7
Pritesh S Karia, Frederick C Morgan, Emily Stamell Ruiz, Chrysalyne D Schmults
Importance: Perineural invasion (PNI) in cutaneous squamous cell carcinoma (CSCC) has been associated with an increased risk of poor outcomes. Patients with PNI may present with clinical symptoms and/or radiologic evidence of PNI (clinical PNI [CPNI]), yet most patients are asymptomatic and PNI is often found on histologic examination (incidental PNI [IPNI]). Evidence-based estimates of the risks of disease-related outcomes comparing IPNI and CPNI are limited in the dermatology literature...
July 5, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28668494/lung-metastasis-in-primary-cutaneous-adenoid-cystic-carcinoma-clinicopathological-evaluation-of-a-rare-case-with-review-of-literature
#8
Gunjesh Kumar Singh, Pragya Singh, Jaspreet Kaur, Rakesh Kumar
Primary cutaneous adenoid cystic carcinoma (ACC) is an extremely rare and indolent cutaneous malignancy with very infrequent distant metastasis. We present a case of primary cutaneous ACC with bilateral lung metastases in a 57-year-old male along with literature review. To the best of our knowledge this is the tenth case of primary cutaneous ACC reported presenting with distant metastasis.
June 28, 2017: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/28657384/cutaneous-metastasis-from-vulvar-squamous-cell-carcinoma-a-rare-occurrence-that-should-not-be-forgotten
#9
Nicolò Bizzarri, Valerio Gaetano Vellone, Luca Parodi, Luana Calanni Fraccono, Valentina Ghirardi, Sergio Costantini, Mario Valenzano Menada, Paolo Sala
Vulvar cancer accounts for 5% of the female genital tract cancers. Cutaneous metastases from vulvar cancer are extremely rare and for this reason, it can be difficult to reach a diagnosis with a consequent delay in the treatment. A systematic literature review of articles on this subject was conducted through a MEDLINE-based search for articles published in English or French. To date, 16 cases (including ours unpublished) of cutaneous metastasis from vulvar cancer have been reported. Cutaneous metastasis can occur from any stage of vulvar cancer, even after a short period...
June 28, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28654578/microcystic-adnexal-carcinoma-a-review-of-the-literature
#10
Shayna Gordon, Caroline Fischer, Ann Martin, Ilana S Rosman, M Laurin Council
BACKGROUND: Microcystic adnexal carcinoma (MAC) is a rare, locally aggressive cutaneous neoplasm that commonly occurs on the face. OBJECTIVE: The purpose of this article is to comprehensively review the current literature on MAC pertaining to epidemiology, pathogenesis, clinical presentation, histology, immunohistochemistry, prognosis, follow-up, and treatment. MATERIALS AND METHODS: An extensive literature review was conducted using OVID MEDLINE and PubMed to identify articles relating to MAC...
June 23, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28653452/cutaneous-implantation-of-papillary-thyroid-carcinoma-secondary-to-percutaneous-ethanol-injection-into-nodal-metastasis
#11
Enrique Rodríguez-Lomba, Irene Molina-López, Verónica Parra-Blanco, Ricardo Suárez-Fernández, Cristina Ciudad-Blanco
Papillary thyroid carcinoma is the most common malignant neoplasm of the thyroid gland, accounting for 50-89% of the cases. It usually presents as a well-differentiated, slow-growing, malignant disease with common spread to locoregional lymph nodes and high recurrence rates. In patients with limited cervical lymph node metastases who are not candidates for surgery or radioiodine therapy, percutaneous ethanol injection (PEI) guided by ultrasonography has proven to be a valuable treatment alternative. This article is protected by copyright...
June 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28633745/carcinoma-hemorrhagiectoides-case-report-of-an-uncommon-presentation-of-cutaneous-metastatic-breast-carcinoma
#12
Roberto Cullen Aravena, Daniella Cullen Aravena, Margarita Jo Velasco, Alejandra Queirolo González, Luis Requena
In most cases, cutaneous metastases develop after the diagnosis of the primary internal malignancy has been established, but sometimes they can be discovered earlier or simultaneously. We describe a case of a 90-year-old woman who presented to the emergency room in poor general condition, with cutaneous lesions characterized by hot, infiltrated, violaceous and erythematous plaques involving the left chest wall. The clinical and histopathological findings were consistent with the recently described variant of inflammatory cutaneous metastatic carcinoma named carcinoma hemorrhagiectoides...
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28632813/cutaneous-metastasis-of-a-pulmonary-carcinoid-tumor
#13
Leyre Falto-Aizpurua, Sarah Seyfer, Bhuvaneswari Krishnan, Ida Orengo
Carcinoid tumors are uncommon neoplasms of neuroendocrine origin that generally arise in the gastrointestinal or bronchopulmonary tracts and typically are characterized by an indolent clinical course. Metastases from these primary neoplasms more commonly affect the viscera, with rare reports of cutaneous metastases to the skin. We report the case of a patient with a cutaneous carcinoid metastasis that was incidentally brought to our attention because of the exquisite tenderness of the lesion. A brief review of the literature also is provided...
May 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28632698/primary-cutaneous-angiosarcoma-mimicking-metastasis-on-18f-fdg-pet-ct-in-woman-with-cervix-cancer
#14
Jae Pil Hwang
Primary cutaneous angiosarcoma is a rare vascular tumor usually affecting the whole body, and its hypermetabolic features on F-FDG PET/CT may be confused with those of infection, metastasis, or primary malignancy. This is a case report of a cutaneous angiosarcoma of the lower anterior abdomen showing increased FDG uptake on F-FDG PET/CT mimicking a cutaneous metastasis in an 84-year-old woman with cervical cancer.
June 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28616154/cutaneous-presentation-of-gastrointestinal-adenocarcinoma
#15
Aditi Halder, Artiene Tatian, A Cristina Vargas, Rooshdiya Karim, Mark Latt
Seeding of a central nervous system malignancy to the abdominal cavity is an uncommon but well documented complication of a ventriculoperitoneal (VP) shunt. However, the metastasis of a primary gastrointestinal cancer to the skin via a VP shunt is extremely rare. We report the clinical case of an 85-year-old male who presented with a right upper quadrant nodule over his shunt, which on histopathology and tumour marker profile was diagnosed as an adenocarcinoma of likely upper gastrointestinal origin. This case illustrates the importance of proceeding to biopsy to inform prognosis and management, despite the risks of shunt infection...
June 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28578604/does-palliative-chemotherapy-provide-a-palliative-effect-on-symptoms-in-late-palliative-stages-an-interview-study-with-oncologists
#16
Peter Strang, Jenny Bergqvist
BACKGROUND: The possible chemotherapy effects on symptoms in late stages of palliative chemotherapy are seldom registered in clinical practice or investigated as primary outcomes. The aim was therefore to study physicians' opinions and experiences about chemotherapy effects on symptoms. MATERIAL AND METHODS: Thirty-five physicians (mainly oncologists) with variation as regards age, gender and experience were included in a qualitative study with semi-structured interviews...
June 3, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28573764/cutaneous-squamous-cell-carcinoma-of-the-lip-a-population-based-analysis
#17
Aykut A Unsal, Aylin B Unsal, Tara E Henn, Soly Baredes, Jean Anderson Eloy
OBJECTIVES/HYPOTHESIS: The role of cumulative ultraviolet (UV) radiation in cutaneous squamous cell carcinoma of the lip (CSCCL) is well understood. This study seeks to evaluate overall survival as well as incidence and demographics across geographic regions, given differences in UV exposure across the United States. STUDY DESIGN: Retrospective population-based analysis. METHODS: A total of 14,901 CSCCL cases were identified as being from the West, Midwest, South, or Northeast, utilizing the Surveillance, Epidemiology, and End Results registry from 1973 to 2013...
June 2, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28570390/lymph-node-metastasis-with-both-components-of-combined-cutaneous-squamous-cell-carcinoma-merkel-cell-neuroendocrine-carcinoma
#18
Jorge Navarrete, Natalia Gugelmeier, María Eugenia Mazzei, Sergio González, Juan J Barcia, Julio Magliano
No abstract text is available yet for this article.
May 22, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28539983/-clown-nose-as-first-manifestation-of-squamous-cell-carcinoma-of-the-lung
#19
Joaquim Marcoval, Laura Martínez-Molina, Montserrat Bonfill-Ortí, Francesc Valentí-Medina
BACKGROUND: Skin metastases occur in 0.7% to 9% of all patients with cancer and are usually considered a late event in the evolution of most visceral carcinomas. The development of a nodular metastatic lesion on the nasal tip is known as clown nose sign. MAIN OBSERVATION: We report a 64-year-old man that developed a nodular lesion on his nasal tip as first manifestation of squamous lung carcinoma. CONCLUSION: The biopsy of the cutaneous metastasis may be helpful to histopathologically confirm the suspected primary tumour avoiding invasive diagnostic procedures...
March 31, 2017: Journal of Dermatological Case Reports
https://www.readbyqxmd.com/read/28538886/cutaneous-angiosarcoma-report-of-three-different-and-typical-cases-admitted-in-a-unique-dermatology-clinic
#20
Aline Neves Freitas Cabral, Rafael Henrique Rocha, Ana Cristina Vervloet do Amaral, Karina Bittencourt Medeiros, Paulo Sérgio Emerich Nogueira, Lucia Martins Diniz
Angiosarcoma is a rare and aggressive tumor with high rates of metastasis and relapse. It shows a particular predilection for the skin and superficial soft tissues. We report three distinct and typical cases of angiosarcoma that were diagnosed in a single dermatology clinic over the course of less than a year: i) Angiosarcoma in lower limb affected by chronic lymphedema, featuring Stewart-Treves syndrome; ii) a case of the most common type of angiosarcoma loated in the scalp and face of elderly man and; iii) a skin Angiosarcoma in previously irradiated breast...
March 2017: Anais Brasileiros de Dermatologia
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