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Hyperthyroidism

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https://www.readbyqxmd.com/read/29168473/yangxin-tongmai-formula-ameliorates-impaired-glucose-tolerance-in-children-with-graves-disease-through-upregulation-of-the-insulin-receptor-levels
#1
Yan-Hong Luo, Min Zhu, Dong-Gang Wang, Yu-Sheng Yang, Tao Tan, Hua Zhu, Jian-Feng He
Graves' disease (GD) is the leading cause of hyperthyroidism, and the majority of GD patients eventually develop disorders of glucose handling, which further affects their quality of life. Yangxin Tongmai formula (YTF) is modified from a famous formula of traditional Chinese medicine for the treatment of cardiovascular diseases. In this study we investigated the potential effects of YTF in the treatment of pediatric GD patients with impaired glucose tolerance. Forty pediatric GD patients and 20 healthy children were recruited for this clinical study...
November 23, 2017: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/29165912/reproducibility-of-radioactive-iodine-uptake-raiu-measurements
#2
Matthieu Pelletier-Galarneau, Patrick Martineau, Ran Klein, Matthew Henderson, Lionel S Zuckier
BACKGROUND: Measurement of radioactive iodine uptake (RAIU) is an important aspect of the assessment and treatment of patients with hyperthyroidism. Its uncertainty affects how much of a true change in RAIU can be detected as well as appropriateness of the therapy dosage upon which it is based. In this study, a method of estimating the reproducibility and least significant change (LSC) values for RAIU measurements, and the implications of the values observed are discussed, with emphasis on application to quality assurance initiatives...
November 22, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29162475/-thyrotropin-reference-ranges-during-pregnancy-in-the-province-of-huelva-spain
#3
A Ortega Carpio, I Vázquez Rico, M A Castaño López, L Duarte González, M Montilla Álvaro, A Ruiz Reina
OBJECTIVE: The correct diagnosis of hypothyroidism during pregnancy requires knowledge of the local trimester-specific thyrotropin (TSH) reference ranges. When these are not available, the guidelines recommend upper limits of 2.5, 3.0, and 3.0μU/ml for the 1(st), 2(nd), and 3(rd) trimesters, respectively. The aim is to establish the reference range for our local population. MATERIAL AND METHODS: A population-based observational study was performed on healthy pregnant women from 11 healthcare centres in the province of Huelva...
November 18, 2017: Semergen
https://www.readbyqxmd.com/read/29159003/toxic-adenoma-in-a-patient-with-thyroid-hemiagenesis
#4
Emin Gurleyik, Sami Dogan, Fuat Cetin, Fatih Gursoy, Alper M Ipor
Thyroid hemiagenesis (TH) is a rare congenital anomaly that is usually asymptomatic. Functional disorders of the thyroid make the patient symptomatic. TH is usually and incidentally established during evaluation of patients with symptomatic thyroid pathology. We report the case of a patient of TH who became symptomatic with hyperactivity of the gland. The patient presented with signs and symptoms of thyrotoxicosis. Physical examination revealed asymmetric nodular goiter at the right lobe. Biochemical analysis established the diagnosis of hyperthyroidism...
September 17, 2017: Curēus
https://www.readbyqxmd.com/read/29151324/thyroid-malignancy-risk-in-different-clinical-thyroid-diseases
#5
Ahmet Dirikoç, Sevgül Fakı, Hüsniye Başer, Didem Özdemir, Cevdet Aydın, Reyhan Ersoy, Mehmet Kılıç, Aydan Kılıçarslan, Bekir Çakır
Background/aim: To evaluate the malignancy risk of thyroid nodules in different clinical thyroid diseases. Materials and methods: Patients who underwent thyroidectomy between 2007 and 2014 were grouped as euthyroid, hypothyroid, and hyperthyroid. Further classification was made depending on the presence of solitary/multiple thyroid nodules. Results: Among 2870 patients, 1719 (59.9%) were euthyroid, 962 (33.5%) were hyperthyroid, and 189 (6.6%) were hypothyroid. Overall malignancy was detected in 980 (34.1%) patients...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29142837/preoperative-management-in-patients-with-graves-disease
#6
REVIEW
Eliana Piantanida
Graves' disease is the most frequent cause of hyperthyroidism in iodine-sufficient geographical areas and is characterized by the presence in patients' serum of autoantibodies directed against the thyrotropin receptor (TRAb) that cause overproduction and release of thyroid hormones. Clinical presentation results from both hyperthyroidism and underlying autoimmunity. The diagnosis is based on characteristic clinical features and biochemical abnormalities. If serum thyrotropin (TSH) is low, serum free thyroxine (FT4) and free triiodothyronine (FT3) concentrations should be measured to distinguish between subclinical (with normal circulating thyroid hormones) and overt hyperthyroidism (with increased circulating thyroid hormones)...
October 2017: Gland Surgery
https://www.readbyqxmd.com/read/29142547/an-evaluation-of-thyroid-autoimmunity-in-patients-with-beta-thalassemia-minor-a-case-control-study
#7
Ali Ramazan Benli, Sati Sena Yildiz, Mehmet Ali Cikrikcioglu
Objective: The tendency to autoimmune diseases has been reported to be increased in beta thalassemia minor (BTM). The aim of this study was to evaluate whether thyroid autoimmunity is higher in BTM. Methods: Patients with BTM (n=86) and a healthy control group (n=93) were included in this cross-sectional case-control study. The two groups were compared in terms of anti-thyroglobulin (anti-TG) and anti-thyroid peroxidase (anti-TPO) and thyroid hormones. Results: In the BTM group, thyroid hormones and serum anti-TG and anti-TPO antibody levels were not statistically different from those of the control group...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29140921/response-to-oral-lithium-as-an-adjunctive-therapy-during-radioiodine-treatment-for-hyperthyroidism
#8
Sandip Basu, Amit Abhyankar
No abstract text is available yet for this article.
December 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29140920/oral-lithium-as-an-adjunctive-therapy-during-radioiodine-treatment-for-hyperthyroidism
#9
Emmanuel N B Hammond, Yaw A Amoako, Mboyo-Di-Tamba W H Vangu
No abstract text is available yet for this article.
December 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29138656/-hyperthyroidism-in-children-at-the-university-hospital-in-dakar-senegal
#10
Djibril Boiro, Demba Diédhiou, Babacar Niang, Djiby Sow, Mandiaye Mbodj, Anna Sarr, Aliou Abdoulaye Ndongo, Aliou Thiongane, Modou Guèye, Lamine Thiam, Ndiogou Seck, Yaay Joor Dieng, Abou Ba, Idrissa Demba Ba, Ibrahima Mané Diallo, Ousmane Ndiaye, Said Nourou Diop
Introduction: Hyperthyroidism in children is rare and constitutes a problem because of its psychosomatic impact. This study aimed to present an overview of the state of knowledge on these aspects in children from Dakar. Methods: We conducted a multicenter, descriptive study over a period of 15 years. We evaluated the epidemiological, clinical and etiologic aspects of hyperthyroidism in children. Results: 239 patients were included in the study with a prevalence of 2...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29137470/controversies-in-management-of-hyperthyroidism-during-pregnancy
#11
Fereidoun Azizi, Atieh Amouzegar
No abstract text is available yet for this article.
October 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29137069/graves-disease-following-radioiodine-therapy-for-toxic-adenoma-clinical-case-report
#12
Guohua Shen, Futao Cui, Rui Huang, Anren Kuang
RATIONALE: There is a low risk of developing Graves disease (GD) with elevated thyrotropin receptor antibodies (TRAbs) in patients undergoing radioiodine therapy for toxic adenoma. PATIENT CONCERNS: An old female patient with a history of Hashimoto thyroiditis was referred to our department due to thyrotoxic symptoms. After the administration of radioiodine, a significant remission was achieved. However, after 4 months, she was referred to our department again due to recurrence of hyperthyroid symptoms...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29133273/plasma-free-thyroxine-in-the-upper-quartile-is-associated-with-an-increased-incidence-of-major-cardiovascular-events-in-older-men-that-do-not-have-thyroid-dysfunction-according-to-conventional-criteria
#13
Jonathan Golledge, Graeme J Hankey, Osvaldo P Almeida, Leon Flicker, Paul E Norman, Bu B Yeap
BACKGROUND: The aim of this study was to assess the association of plasma free thyroxine (FT4) and serum thyroid stimulating hormone (TSH) concentrations with the past diagnosis of cardiovascular disease and incidence of new cardiovascular events in older men with no known thyroid disease. METHODS: This study involved a cohort of community-recruited older men without known thyroid disease. Plasma FT4 and serum TSH were measured by immunoassay. Past cardiovascular disease diagnosis was defined through questionnaire data...
October 29, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29132170/thyroid-dysfunction-states-and-incident-cardiovascular-events-the-tehran-thyroid-study
#14
Maryam Tohidi, Arash Derakhshan, Samaneh Akbarpour, Atieh Amouzegar, Ladan Mehran, Aidin Baghbani-Oskouei, Fereidoun Azizi, Farzad Hadaegh
The objective of the study was to investigate the relation of different thyroid function states with the incidence of cardiovascular disease (CVD)/coronary heart disease (CHD) among a Middle-Eastern population with a high incidence of CVD/CHD. A total of 3975 participants entered the study (43.6% men). According to their thyroid stimulating hormone (TSH) and free thyroxin (FT4) levels, the participants were categorized into 5 groups: euthyroid, subclinical hypothyroidism, overt hypothyroidism, subclinical hyperthyroidism, and overt hyperthyroidism...
November 13, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29131274/expression-level-and-clinical-significance-of-il-2-il-6-and-tgf-%C3%AE-in-elderly-patients-with-goiter-and-hyperthyroidism
#15
L-F Lv, H-Y Jia, H-F Zhang, Y-X Hu
OBJECTIVE: To investigate the level of expression and the clinical significance of IL-2 (interleukin-2), IL-6 (interleukin-6) and TGF-β (transforming growth factor-β) in elderly patients with goiter and hyperthyroidism. PATIENTS AND METHODS: Gender, age, course of disease, BMI (Body Mass Index), serum FT3 (Free triiodothyronine-3), FT4 (Free triiodothyronine-4), TT3 (Total triiodothyronine-3), TT4 (Total triiodothyronine-4), TSH (Thyroid Stimulating Hormone) and clinical manifestations on admission and other general clinical data and laboratory examination results were collected and statistically analyzed as case group in 128 elderly patients with goiter and hyperthyroidism...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29130077/study-of-the-factors-leading-to-fetal-and-neonatal-dysthyroidism-in-children-of-patients-with-graves-disease
#16
Maïa Banigé, Candice Estellat, Valerie Biran, Luc Desfrere, Valerie Champion, Alexandra Benachi, Yves Ville, Marc Dommergues, Pierre-Henri Jarreau, Mostafa Mokhtari, Claire Boithias, Frederic Brioude, Laurent Mandelbrot, Pierre-François Ceccaldi, Delphine Mitanchez, Michel Polak, Dominique Luton
Context: Neonatal hyperthyroidism was first described in 1912 and in 1964 was shown to be linked to transplacental passage of maternal antibodies. Few multicenter studies have described the perinatal factors leading to fetal and neonatal dysthyroidism. Objective: To show how fetal dysthyroidism (FD) and neonatal dysthyroidism (ND) can be predicted from perinatal variables, in particular, the levels of anti-thyrotropin receptor antibodies (TRAbs) circulating in the mother and child...
June 2017: J Endocr Soc
https://www.readbyqxmd.com/read/29127767/marine-lenhart-syndrome-in-two-adolescents-including-one-with-thyroid-cancer-a-case-series-and-review-of-the-literature
#17
REVIEW
Animesh Sharma
BACKGROUND: The coexistence of functional thyroid nodules and Graves' disease (GD) is a rare condition known as Marine-Lenhart syndrome. Thyroid cancer has been described in several adults, but never in children, with Marine-Lenhart syndrome. This paper discusses the challenges in diagnosis and the unique management of this condition in children, in the context of extant literature. CONTENT: In this case report, two adolescent female patients with Marine-Lenhart syndrome, aged 15 and 16 years, exhibited biochemical evidence of hyperthyroidism, and were found to have unilateral hyperfunctioning thyroid nodules via thyroid scintigraphy...
November 11, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29120649/-thyroid-disease-in-the-czech-republic-the-euthyroid-project-and-the-evaluation-of-the-general-health-insurance-company-epidemiological-data-for-the-period-of-2012-2015
#18
Radovan Bílek, Lenka Horáková, Robert Goš, Václav Zamrazil
Institute of Endocrinology participates in the grant of European Commission EUthyroid (Towards the elimination of iodine deficiency and preventable thyroid-related diseases in Europe), together with other 28 European countries. The role of Institute of Endocrinology in EUthyroid is among other things to ensure access to national registers relating to thyroid diseases. The results presented here correspond to the years 2012-2015 and are based on data from the General Health Insurance Company Czech Republic (VZP CR), which has 6 million insured persons (ratio male : female = 1 : 1)...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29116999/treatment-outcome-of-combined-continuous-venovenous-hemofiltration-and-hemoperfusion-in-acute-paraquat-poisoning-a-prospective-controlled-trial
#19
Changbin Li, Dayong Hu, Wen Xue, Xinhua Li, Zhen Wang, Zisheng Ai, Yaxiang Song, Xinying Liu, Jiafeng Cheng, Shuling Fan, Limin Zhao, Liya Wang, Chandra Mohan, Ai Peng
OBJECTIVES: To investigate whether combined continuous venovenous hemofiltration and hemoperfusion among paraquat-poisoned patients would improve survival. DESIGN: Prospective, controlled interventional study over 4 years. SETTING: Single, tertiary, academic medical center. PATIENTS: We recruited patients admitted to Shanghai Tenth People's Hospital within 48 hours after paraquat ingestion. Exclusions were under 14 years old, ingestion of paraquat with other toxicants, pregnant, a history of chronic pulmonary disease, psychosis, hyperthyroidism, or diabetes with impaired liver or renal function...
November 7, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29116656/all-cause-and-cardiovascular-mortality-risk-after-surgery-versus-radioiodine-treatment-for-hyperthyroidism
#20
P Giesecke, V Frykman, G Wallin, S Lönn, A Discacciati, O Törring, M Rosenqvist
BACKGROUND: Little is known about the long-term side-effects of different treatments for hyperthyroidism. The few studies previously published on the subject either included only women or focused mainly on cancer outcomes. This register study compared the impact of surgery versus radioiodine on all-cause and cause-specific mortality in a cohort of men and women. METHODS: Healthcare registers were used to find hyperthyroid patients over 35 years of age who were treated with radioiodine or surgery between 1976 and 2000...
November 8, 2017: British Journal of Surgery
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