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Central aortic pressure

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https://www.readbyqxmd.com/read/29785654/a-systematic-review-and-meta-analysis-of-the-use-of-resuscitative-endovascular-balloon-occlusion-of-the-aorta-in-the-management-of-major-exsanguination
#1
REVIEW
B L S Borger van der Burg, Thijs T C F van Dongen, J J Morrison, P P A Hedeman Joosten, J J DuBose, T M Hörer, R Hoencamp
BACKGROUND: Circulatory collapse is a leading cause of mortality among traumatic major exsanguination and in ruptured aortic aneurysm patients. Approximately 40% of patients die before hemorrhage control is achieved. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an adjunct designed to sustain the circulation until definitive surgical or endovascular repair. A systematic review was conducted for the current clinical use of REBOA in patients with hemodynamic instability and to discuss its potential role in improving prehospital and in-hospital outcome...
May 21, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29779091/two-years-of-maintenance-hemodialysis-has-a-pronounced-effect-on-arterial-stiffness-progression
#2
Agne Laucyte-Cibulskiene, Laurynas Rimsevicius, Liutauras Gumbys, Dileta Valanciene, Marius Miglinas
BACKGROUND: The change of aortic stiffness, but not the particular baseline value, plays a crucial role in estimating the patient risk with end-stage renal disease. Therefore, we aimed to analyze the evolution of central and peripheral arterial stiffness in hemodialysis population without previous cardiovascular events during a 2-year follow-up. METHODS: 60 hemodialysis patients (mean age 57.61 ± 13.01 years) were prospectively interviewed, and they underwent blood tests, chest X-ray for aortic calcification evaluation and pulse wave velocity (PWV) measurements at the baseline, after 6 months and after 2 years of observation period...
May 19, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29765328/long-term-consumption-of-cuban-policosanol-lowers-central-and-brachial-blood-pressure-and-improves-lipid-profile-with-enhancement-of-lipoprotein-properties-in-healthy-korean-participants
#3
Suk-Jeong Kim, Dhananjay Yadav, Hye-Jeong Park, Jae-Ryong Kim, Kyung-Hyun Cho
Metabolic syndrome is closely associated with higher risk of hypertension, cardiovascular disease (CVD), diabetes and stroke. The aim of the present study was to investigate the long-term effects of policosanol supplementation on blood pressure (BP) and the lipid profile in healthy Korean participants with pre-hypertension (systolic 120-139 mmHg, diastolic 85-89 mmHg). This randomized, double-blinded, and placebo-controlled trial included 84 healthy participants who were randomly assigned to three groups receiving 10 mg of policosanol, 20 mg of policosanol, or placebo for 24 weeks...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29761089/association-of-haemodynamic-indices-of-central-and-peripheral-pressure-with-subclinical-target-organ-damage
#4
Junli Zuo, Shaoli Chu, Isabella Tan, Mark Butlin, Jiehui Zhao, Alberto Avolio
Background: Central aortic pressure has often been shown to be more closely associated with markers of vascular function and incidence of cardiovascular events compared to peripheral pressure. However, the potential clinical use of central aortic or peripheral haemodynamic indices as markers of target organ damage (TOD) has not been fully established. Methods: We evaluated associations of TOD with central aortic and peripheral haemodynamic indices (central aortic [cPP] and peripheral pulse pressure [pPP], central aortic augmentation index, and central and peripheral waveform factor) in 770 hospital inpatients (age 60 ± 10 years, 473 males) with primary hypertension...
March 2018: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/29756692/the-presence-of-elastic-compression-stockings-reduces-the-fluid-responsiveness-of-patients-in-the-operating-room
#5
Elie Zogheib, Julien Maizel, Nabil Cherradi, Ammar Benammar, Béatrice Labont, Abdel Hchikat, Michael Bernasinski, Faouzi Trojette, Michel Slama, Hervé Dupont
BACKGROUND: To investigate whether elastic compression stockings (ECS) can affect fluid responsiveness parameters before and during passive leg raising (PLR) maneuvers. METHODS: In the operating room (OR), we performed a prospective study including patients referred for cardiac surgery. Blood pressure (BP), ΔPP, heart rate (HR), central venous pressure (CVP), stroke volume (SV) and aortic blood flow (ABF) (by esophageal doppler) were measured according to four conditions: supine position without ECS (baseline 1), lower limbs raised to an angle of 45° (PLR 1), returned to the supine position with ECS (baseline 2), then a second PLR maneuver with ECS was performed (PLR 2)...
May 11, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29744617/cardiac-magnetic-resonance-assessment-of-central-and-peripheral-vascular-function-in-patients-undergoing-renal-sympathetic-denervation-as-predictor-for-blood-pressure-response
#6
Karl Fengler, Karl-Philipp Rommel, Stephan Blazek, Maximilian Von Roeder, Christian Besler, Christian Lücke, Matthias Gutberlet, Jennifer Steeden, Michael Quail, Steffen Desch, Holger Thiele, Vivek Muthurangu, Philipp Lurz
BACKGROUND: Most trials regarding catheter-based renal sympathetic denervation (RDN) describe a proportion of patients without blood pressure response. Recently, we were able to show arterial stiffness, measured by invasive pulse wave velocity (IPWV), seems to be an excellent predictor for blood pressure response. However, given the invasiveness, IPWV is less suitable as a selection criterion for patients undergoing RDN. Consequently, we aimed to investigate the value of cardiac magnetic resonance (CMR) based measures of arterial stiffness in predicting the outcome of RDN compared to IPWV as reference...
May 9, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29729330/paraoxonase-2-prevents-the-development-of-heart-failure
#7
Wei Li, David Kennedy, Zhili Shao, Xi Wang, Andre Klaassen Kamdar, Malory Weber, Kayla Mislick, Kathryn Kiefer, Rommel Morales, Brendan Agatisa-Boyle, Diana M Shih, Srinivasa T Reddy, Christine S Moravec, W H Wilson Tang
BACKGROUND: Mitochondrial oxidation is a major source of reactive oxygen species (ROS) and mitochondrial dysfunction plays a central role in development of heart failure (HF). Paraoxonase 2 deficient (PON2-def) mitochondria are impaired in function. In this study, we tested whether PON2-def aggravates HF progression. METHODS AND RESULTS: Using qPCR, immunoblotting and lactonase activity assay, we demonstrate that PON2 activity was significantly decreased in failing hearts despite increased PON2 expression...
May 2, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29707808/pooled-diagnostic-accuracy-of-resting-distal-to-aortic-coronary-pressure-referenced-to-fractional-flow-reserve-the-importance-of-resting-coronary-physiology
#8
Rohit Maini, John Moscona, Gursukhman Sidhu, Paul Katigbak, Camilo Fernandez, Anand Irimpen, Owen Mogabgab, Charisse Ward, Rohan Samson, Thierry LeJemtel
INTRODUCTION: Both resting and hyperemic physiologic methods to guide coronary revascularization improve cardiovascular outcomes compared with angiographic guidance alone. Fractional flow reserve (FFR) remains underutilized due to concerns regarding hyperemia, prompting study of resting distal to aortic coronary pressure (Pd/Pa). Pd/Pa is a vasodilator-free resting index unlike FFR. While Pd/Pa is similar to another resting index, instantaneous wave-free ratio (iFR), it is a whole-cycle measurement not limited to the wave-free diastolic period...
April 29, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29701425/analgesia-management-for-mitral-valve-repair-via-minithoracotomy-a-case-report
#9
Andreia Fernandes, Clara Gaio Lima, Nelson Paulo, Catarina Celestino, Ana Fonte Boa, Fátima Lima, Manuela Vieira
INTRODUCTION: Minimally invasive cardiac surgery (MICS), via minithoracotomy, is thought to be a fast track to extubation and recovery after surgery. Chronic pain, due to intercostal nerve injury, develops in up to 50% of postthoracotomy patients.A number of regional anaesthesia and analgesia techniques may be employed, and the anaesthesiologists play a key role in facilitating optimal outcomes after surgery. METHODS: We report a case of postoperative pain management with a local anesthetic infiltration for MICS...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29695375/a-comparison-and-calibration-of-a-wrist-worn-blood-pressure-monitor-for-patient-management-assessing-the-reliability-of-innovative-blood-pressure-devices
#10
Sarah Melville, Robert Teskey, Shona Philip, Jeremy A Simpson, Sohrab Lutchmedial, Keith R Brunt
BACKGROUND: Clinical guidelines recommend monitoring of blood pressure at home using an automatic blood pressure device for the management of hypertension. Devices are not often calibrated against direct blood pressure measures, leaving health care providers and patients with less reliable information than is possible with current technology. Rigorous assessments of medical devices are necessary for establishing clinical utility. OBJECTIVE: The purpose of our study was 2-fold: (1) to assess the validity and perform iterative calibration of indirect blood pressure measurements by a noninvasive wrist cuff blood pressure device in direct comparison with simultaneously recorded peripheral and central intra-arterial blood pressure measurements and (2) to assess the validity of the measurements thereafter of the noninvasive wrist cuff blood pressure device in comparison with measurements by a noninvasive upper arm blood pressure device to the Canadian hypertension guidelines...
April 25, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29684371/repair-of-ductus-or-hemi-truncus-to-one-lung-and-major-aortopulmonary-collaterals-to-the-other-lung
#11
Richard D Mainwaring, Tatiana R Rosenblatt, William L Patrick, Michael Ma, Lynn Peng, Frank L Hanley
BACKGROUND: There are patients born with pulmonary atresia and a ductus arteriosus or hemi-truncus to one lung and major aortopulmonary collateral arteries (MAPCAs) to the contralateral lung. The purpose of this study was to review our surgical results for this relatively rare subset of patients. METHODS: This was a retrospective review of 35 patients with ductus/hemi-truncus in association with pulmonary atresia with ventricular septal defect and MAPCAs. Our surgical algorithm is bifurcated into two strategies: 1) patients with "favorable" MAPCAs are candidates for single stage complete repair, and 2) patients with "unfavorable" MAPCAs undergo a staged approach...
April 20, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29684105/aortic-pulse-pressure-does-not-adequately-index-cardiovascular-risk-factor-related-changes-in-aortic-stiffness-and-forward-wave-pressure
#12
Tshegofatso H Motau, Gavin R Norton, Pinhas Sareli, Angela J Woodiwiss
Background: Through the impact of conventional risk factors on arteries, several changes in aortic function contribute to cardiovascular events. It is nevertheless uncertain whether these effects are accurately reflected by changes in central aortic pulse pressure (PPc). We therefore aimed to determine the extent to which relations between modifiable risk factors and aortic function translate into increases in PPc. Methods: In 1232 black South Africans from the South West Township (SOWETO) of Johannesburg, we determined risk factors and aortic function from carotid-femoral pulse wave velocity (PWV) and aortic PPc, forward (Pf) and reflected (backward-Pb) wave pressures (applanation tonometry and SphygmoCor software)...
April 19, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29677054/effects-of-acute-aerobic-exercise-on-arterial-stiffness-and-cerebrovascular-pulsatility-in-adults-with-and-without-hypertension
#13
Wesley K Lefferts, Jacob P DeBlois, Candace N Receno, Tiago V Barreira, Tom D Brutsaert, Robert L Carhart, Kevin S Heffernan
OBJECTIVES: Stiffer central arteries, as seen in hypertension (HTN), foster transmission of pulsatile hemodynamics into fragile cerebral vessels. Aerobic exercise is recommended for adults with HTN, but its effects on arterial stiffness and pulsatility in this group are unclear. This study sought to investigate the effect of acute aerobic exercise on arterial stiffness and cerebrovascular pulsatility in 30 adults with treated HTN and 30 age, sex, and BMI-matched adults without HTN (56 ± 6 years, BMI 28...
April 19, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29675613/the-role-of-central-blood-pressure-monitoring-in-the-management-of-hypertension
#14
REVIEW
Adrian Ochoa, Gabriel Patarroyo-Aponte, Mahboob Rahman
PURPOSE OF REVIEW: Central blood pressure is a novel predictor of cardiovascular risk that can be measured in the clinical setting using currently available technology. This paper will review current available methods of central blood pressure monitoring as well as its impact in cardiac and renal disease. RECENT FINDINGS: Both aortic and carotid systolic blood pressure are independently associated with cardiovascular mortality and serious cardiac events. Furthermore, studies show that systolic aortic blood pressure has been shown to be superior predictor of cardiovascular as compared to brachial blood pressure...
April 19, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29663283/eeg-artifact-versus-subclinical-status-epilepticus-in-a-patient-following-cardiac-arrest
#15
Jean E Cibula, Daniel S Demos, Brenda G Fahy
BACKGROUND: A challenge in ICU EEG interpretation is identifying subclinical status epilepticus versus patterns on the ictal-interictal continuum versus other repetitive patterns. In the electrically noisy intensive care unit, identifying and eliminating interference and artifact allow accurate diagnoses from the EEG, avoiding unnecessary treatment or sedation. METHODS: We present a case during Impella (Abiomed Inc, Danvers, MA) continuous flow left ventricular assist device use where the EEG artifact was initially misinterpreted as seizure by the resident and treated as status epilepticus because of the "focal" sharply contoured repetitive pattern...
April 16, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29662306/short-term-vascular-hemodynamic-responses-to-isometric-exercise-in-young-adults-and-in-the-elderly
#16
Renee Hartog, Davide Bolignano, Eric Sijbrands, Giacomo Pucci, Francesco Mattace-Raso
Background: Vascular aging is known to induce progressive stiffening of the large elastic arteries, altering vascular hemodynamics under both rest and stress conditions. In this study, we aimed to investigate changes in vascular hemodynamics in response to isometric handgrip exercise across ages. Participants and methods: We included 62 participants, who were divided into three age categories: 20-40 (n=22), 41-60 (n=20), and 61-80 (n=20) years. Vascular hemodynamics were measured using the Mobil-o-Graph® based on the pulsatile pressure changes in the brachial artery...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29651954/forward-and-backward-aortic-components-and-reflection-indexes-in-children-and-adolescents-determinants-and-role-in-high-pressure-states
#17
Yanina Zocalo, Juan M Castro, Victoria Garcia-Espinosa, Santiago Curcio, Pedro Chiesa, Gustavo Giachetto, Edmundo I Cabrera-Fischer, Daniel Bia
High blood pressure states (HBP) would differ in wave components and reflections indexes, which could associate clinical and prognostic implications. AIMS: 1) to characterize the association of aortic wave components and reflection parameters (backward [Pb], forward [Pf], Pb/Pf ratio and augmentation index [AIx]) with demographic, anthropometric, hemodynamic and arterial parameters in healthy children and adolescents; 2) to generate multivariate prediction models for the associations, to contribute to understand main determinants of Pf, Pb, Pb/Pf and AIx; 3) to identify if differences in wave reflection indexes observed in HBP could be explained by differences in the analyzed parameters...
April 12, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/29613887/clinical-outcomes-and-reduced-pulmonary-artery-pressure-with-intra-aortic-balloon-pump-during-central-extracorporeal-life-support
#18
Sarah Tepper, Moises Baltazar Garcia, Irene Fischer, Amena Ahmed, Anam Khan, Keki R Balsara, Muhammad Faraz Masood, Akinobu Itoh
Patients supported with extracorporeal life support (ECLS) can experience severe complications from increased left ventricular afterload. The intra-aortic balloon pump (IABP) is thought to unload the left ventricle (LV) and is routinely used with ECLS despite conflicting evidence of its clinical benefit. This retrospective, single-center study examined the effect of the simultaneous use of IABP and centrally cannulated ECLS on patient outcomes and provides new insights into IABP-mediated LV unloading. Thirty patients supported with central ECLS and IABP (ECLS-I) were compared with 30 patients with central ECLS alone (ECLS) for cardiogenic shock...
March 30, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29601410/increased-aortic-wave-reflection-contributes-to-higher-systolic-blood-pressure-in-adolescents-born-preterm
#19
Remi R Kowalski, Richard Beare, Jonathan P Mynard, Jeanie L Y Cheong, Lex W Doyle, Joseph J Smolich, Michael M H Cheung
OBJECTIVE: To evaluate the wave reflection characteristics in the aortic arch and common carotid artery of ex-preterm adolescents and assess their relationship to central blood pressure in a cohort followed prospectively since birth. METHODS: Central blood pressures, pulse wave velocity, augmentation index, microvascular reactive hyperemia, arterial distensibility, compliance and stiffness index, and also aortic and carotid wave intensity were measured in 18-year-olds born extremely preterm at below 28 weeks' gestation (n = 76) and term-born controls (n = 42)...
March 29, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29596016/chronic-interval-exercise-training-prevents-bk-ca-channel-mediated-coronary-vascular-dysfunction-in-aortic-banded-mini-swine
#20
T Dylan Olver, Jenna C Edwards, Brian S Ferguson, Jessica A Hiemstra, Pamela K Thorne, Michael A Hill, Maurice Harold Laughlin, Craig A Emter
Conventional treatments have failed to improve the prognosis of heart failure with preserved ejection fraction (HFpEF) patients. Thus, the purpose of this study was to determine the therapeutic efficacy of chronic interval exercise training (IT) on BKCa channel-mediated coronary vascular function in heart failure. We hypothesized chronic interval exercise training would attenuate pressure overload-induced impairments to coronary BKCa channel-mediated function. A translational large animal model with cardiac features of heart failure with preserved ejection fraction was used to test this hypothesis...
March 29, 2018: Journal of Applied Physiology
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