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Central aortic pressure

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https://www.readbyqxmd.com/read/28798874/results-from-survey-to-assess-current-trends-in-surgical-practice-in-the-management-of-women-with-early-stage-cervical-cancer-within-the-bgcs-community-with-an-emphasis-on-routine-frozen-section-examination
#1
Kumar Gubbala, Alexandros Laios, Thulumuru Kavitha Madhuri, Pubudu Pathiraja, Krishnayan Haldar, Sean Kehoe
In the UK, more than 3,200 new cases of cervical cancer are diagnosed each year. Early stage cervical cancer (IA2-IB1) treatment comprises central surgery mainly in the form of radical hysterectomy or fertility sparing surgery including trachelectomy as well as systematic pelvic lymphadenectomy to detect metastases and adjust treatment accordingly. Given the variation in determining the lymph node (LN) status, a major prognosticator, we reviewed the current UK practice of LN assessment in women undergoing surgery for early cervical cancer...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28790231/inflammation-immunity-and-hypertension
#2
Arisya Agita, M Thaha Alsagaff
The immune system, inflammation and hypertension are related to each other. Innate and adaptive immunity system triggers an inflammatory process, in which blood pressure may increase, stimulating organ damage. Cells in innate immune system produce ROS, such as superoxide and hydrogen peroxide, which aimed at killing pathogens. Long-term inflammation process increases ROS production, causing oxidative stress which leads to endothelial dysfunction. Endothelial function is to regulate blood vessel tone and structure...
April 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28759844/circulating-soluble-receptor-for-advanced-glycation-end-product-cross-sectional-associations-with-cardiac-markers-and-subclinical-vascular-disease-in-older-men-with-and-without-diabetes
#3
S Goya Wannamethee, Paul Welsh, Olia Papacosta, Elizabeth A Ellins, Julian P J Halcox, Peter H Whincup, Naveed Sattar
BACKGROUND AND AIMS: The soluble receptor for advanced glycation end products (sRAGE) has been implicated in diabetic vascular complications. We have examined the association between sRAGE and cardiac markers [NT-proBNP and cardiac troponin T (cTnT)] and subclinical vascular markers in older men with and without diabetes. METHODS: We performed a cross-sectional study of 1159 men aged 71-92 years with no history of cardiovascular disease (myocardial infarction, stroke, heart failure, coronary artery bypass graft operation or angioplasty)...
July 12, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28753657/evolution-of-aortic-pressure-during-normal-ageing-a-model-based-study
#4
Stamatia Pagoulatou, Nikolaos Stergiopulos
BACKGROUND: The age-related increase in pulse pressure (PP) and systolic blood pressure (SBP) is often attributed to alterations in the wave reflection profile and augmented contributions of the reflected waves. However, clinical evidence shows that the stiffening of the proximal aorta with age and the consequent augmentation of the forward pressure wave plays an equally important role. The relative importance of the forward and reflected wave components in essential hypertension has not yet been fully elucidated...
2017: PloS One
https://www.readbyqxmd.com/read/28733312/baseline-aortic-pulse-wave-velocity-is-associated-with-central-and-peripheral-pressor-responses-during-the-cold-pressor-test-in-healthy-subjects
#5
Anastasiya Borner, Kyle Murray, Claire Trotter, James Pearson
Cold environmental temperatures increase sympathetic nerve activity and blood pressure, and increase the risk of acute cardiovascular events in aged individuals. The acute risk of cardiovascular events increases with aortic pulse wave velocity as well as elevated central and peripheral pulse pressures. The aim of this study was to examine the independent influence of aortic pulse wave velocity upon central and peripheral pressor responses to sympathetic activation via the cold pressor test (CPT). Twenty-two healthy subjects (age: 18-73 years) completed a CPT with the left hand immersed in 2-4°C water for 3 min...
July 2017: Physiological Reports
https://www.readbyqxmd.com/read/28728652/accuracy-of-fractional-flow-reserve-measurements-in-clinical-practice-observations-from-a-core-laboratory-analysis
#6
Mitsuaki Matsumura, Nils P Johnson, William F Fearon, Gary S Mintz, Gregg W Stone, Keith G Oldroyd, Bernard De Bruyne, Nico H J Pijls, Akiko Maehara, Allen Jeremias
OBJECTIVES: The aim of this study was to compare site-reported measurements of fractional flow reserve (FFR) with FFR analysis by an independent core laboratory (CL). BACKGROUND: FFR is an index of coronary stenosis severity that has been validated in multiple trials and is widely used in clinical practice. However, the incidence of suboptimal FFR measurements is unknown. METHODS: Patients undergoing FFR assessment within the CONTRAST (Can Contrast Injection Better Approximate FFR Compared to Pure Resting Physiology) study had paired, repeated measurements of multiple physiological metrics per local practice...
July 24, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28727703/intrathecal-morphine-improves-hemodynamic-parameters-and-analgesia-in-patients-undergoing-aortic-valve-replacement-surgery-a-prospective-double-blind-randomized-trial
#7
Hamed Elgendy, Hatem A R Helmy
BACKGROUND: Intrathecal morphine (ITM) has been used in hopes of providing good postoperative analgesia in cardiac surgery. Little is known about its use in isolated aortic valve replacement surgery. OBJECTIVES: To evaluate the effects of 7 µ/kg ITM administration in aortic valve replacement in regards to hemodynamics, pain score, and postoperative complications when compared to general anesthesia alone. STUDY DESIGN: A randomized, double-blind trial...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28695310/central-aortic-pulse-pressure-thrombogenicity-and-cardiovascular-risk
#8
Gailing Chen, Kevin P Bliden, Rahul Chaudhary, Fang Liu, Himabindu Kaza, Eliano P Navarese, Udaya S Tantry, Paul A Gurbel
High central aortic pulse pressure (CPP) and thrombin-induced platelet-fibrin clot strength (TIP-FCS) have been associated with ischemic outcomes in patients with coronary artery disease in separate studies. But, the ischemic risk associated with these factors has never been analyzed in a single study and their interrelation is unknown. The primary aim of the study was to establish cut points for CPP and TIP-FCS measured at the time of catheterization associated with long term major adverse cardiovascular events...
August 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28692445/normal-cerebral-vascular-pulsations-in-humans-changes-with-age-and-implications-for-microvascular-disease
#9
Mi O Kim, Yan Li, Fangfei Wei, Jiguang Wang, Michael F O'Rourke, Audrey Adji, Alberto P Avolio
BACKGROUND: Cerebral syndromes in older humans, secondary stroke in younger persons following trauma, and sickle cell anaemia in children, are linked by unexplained microvascular damage and high cerebral pressure or flow pulsations. The aim of this study was to characterize age-related pressure and flow waveforms patterns entering the brain, to explain these in terms of disturbed physiological function, and to consider clinical implications. METHOD: Blood flow velocity waves were measured in four cerebral vascular territories by transcranial Doppler of 1020 apparently normal patients (497 men, 21-78 years)...
July 7, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28683960/arterial-stiffening-with-exercise-in-patients%C3%A2-with-heart-failure-and-preserved%C3%A2-ejection-fraction
#10
Yogesh N V Reddy, Mads J Andersen, Masaru Obokata, Katlyn E Koepp, Garvan C Kane, Vojtech Melenovsky, Thomas P Olson, Barry A Borlaug
BACKGROUND: Aortic stiffening and reduced nitric oxide (NO) availability may contribute to the pathophysiology of heart failure with preserved ejection fraction (HFpEF). OBJECTIVES: This study compared indices of arterial stiffness at rest and during exercise in subjects with HFpEF and hypertensive control subjects to examine their relationships to cardiac hemodynamics and determine whether exertional arterial stiffening can be mitigated by inorganic nitrite. METHODS: A total of 22 hypertensive control subjects and 98 HFpEF subjects underwent hemodynamic exercise testing with simultaneous expired gas analysis to measure oxygen consumption...
July 11, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28683363/association-between-markers-of-arterial-stiffness-and-atrial-fibrillation-in-the-circulatory-risk-in-communities-study-circs
#11
Renzhe Cui, Kazumasa Yamagishi, Isao Muraki, Mina Hayama-Terada, Mitsumasa Umesawa, Hironori Imano, Yuanying Li, Ehab S Eshak, Tetsuya Ohira, Masahiko Kiyama, Takeo Okada, Akihiko Kitamura, Takeshi Tanigawa, Hiroyasu Iso
BACKGROUND AND AIMS: Limited evidence is available on the association between markers of arterial stiffness and the prevalence of atrial fibrillation among Asian populations. Therefore, we examined those associations in the Japanese population. METHODS: We conducted a cross-sectional population-based study of 4264 men and women aged 40-79 years. The augmentation index (AI), a marker of arterial stiffness, was calculated as the ratio of central pulse pressure/brachial pulse pressure, where the AI and central aortic pressure were measured by an automated tonometer: the HEM-9000AI device (Omron Healthcare co...
June 22, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28682245/a-fiber-bragg-grating-sensor-for-radial-artery-pulse-waveform-measurement
#12
Dagong Jia, Jing Chao, Shuai Li, Hongxia Zhang, Yingzhan Yan, Tiegen Liu, Ye Sun
In this paper, we report the design and experimental validation of a novel optical sensor for radial artery pulse measurement based on fiber Bragg grating (FBG) and lever amplification mechanism. Pulse waveform analysis (PWA) is a diagnostic tool for clinical examination and disease diagnosis. High fidelity radial artery pulse waveform has been investigated in clinical studies for estimating central aortic pressure which is proved to be predictors of cardiovascular diseases. As a three-dimensional cylinder, the radial artery needs to be examined from different locations to achieve optimal pulse waveform for estimation and diagnosis...
June 30, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28677364/dapagliflozin-administration-on-visceral-adiposity-blood-pressure-and-aortic-central-pressure-in-overweight-patients-without-type-2-diabetes
#13
Manuel González-Ortiz, Fernando Grover-Páez, Cristal Díaz-Cruz, Anayeli de J Patiño-Laguna, Luis D López-Murillo, Esperanza Martínez-Abundis
No abstract text is available yet for this article.
August 2017: Minerva Medica
https://www.readbyqxmd.com/read/28669329/effect-of-low-5-mg-vs-high-20-40-mg-rosuvastatin-dose-on-24h-arterial-stiffness-central-haemodynamics-and-non-alcoholic-fatty-liver-disease-in-patients-with-optimally-controlled-arterial-hypertension
#14
Eudoxia Mitsiou, Chrysoula Boutari, Vasilios Kotsis, Eleni Georgianou, Michael Doumas, Asterios Karagiannis, Vasilios G Athyros
OBJECTIVE: Arterial stiffness (AS) and non-alcoholic fatty liver diseases (NAFLD) are 2 related, prevalent, risk predictors of cardiovascular disease (CVD). We assessed the effect of low dose (5 mg/day) vs high dose (20-40 mg/day) rosuvastatin on aortic elasticity and central haemodynamics as well as on NAFLD in patients with arterial hypertension (AH). PATIENTS-METHODS: Forty patients with optimally controlled AH were randomised to 2 rosuvastatin doses and followed for 6 months...
June 30, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28665886/ablation-of-toll-like-receptor-4-mitigates-central-blood-pressure-response-during-hyperhomocysteinemia
#15
Nevena Jeremic, Gregory J Weber, Anastasia Familtseva, Naira Metreveli, Suresh C Tyagi
OBJECTIVE: The objective of this study was to define the mechanisms of homocysteine-induced effects on the aortic wall that promote vascular remodeling and hypertension as well as explore the role of Toll-like receptor 4 in homocysteine-induced effects. METHOD: Five strains of mice were utilized in this study: C57BL/6J, C3H/HeOuJ, CBS+/-, C3H/HeJ and CBS+/-/C3H. Aorta, heart and blood were collected at the end of the experiments. Blood pressure (BP) was recorded using noninvasive tail cuff method...
June 29, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28661960/longitudinal-study-of-the-influence-of-lung-function-on-vascular-health-from-adolescence-to-early-adulthood-in-a-british-multiethnic-cohort
#16
Yao Lu, Lum Sooky, Maria João Silva, Oarabile R Molaodi, Alexis Karamanos, J Kennedy Cruickshank, Seeromanie Harding
BACKGROUND: Vascular and lung function develop and decline over the life course; both predict cardiovascular events and mortality but little is known of how they develop over time. We analysed their relationship in a multiethnic cohort study to test whether lung function from early adolescence to young adulthood affected vascular indices. METHODS: 'DASH' (http://dash.sphsu.mrc.ac.uk) included 6643 children aged 11-13 years in 2003; a representative 10% sample (n = 665) participated in a pilot follow-up in 2013...
July 18, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28639723/changes-in-the-inspiratory-pattern-contribute-to-modulate-the-sympathetic-activity-in-sino-aortic-denervated-rats
#17
Mateus R Amorim, Leni G H Bonagamba, George M P R Souza, Davi J A Moraes, Benedito H Machado
What is the central question of this study? Sino-aortic denervated (SAD) rats present normal levels of sympathetic activity and mean arterial pressure. However, neural mechanisms regulating the sympathetic activity in the absence of arterial baroreceptors remain unclear. Considering that respiration modulates the sympathetic activity, we hypothesize that changes in the respiratory network contribute to keep the sympathetic outflow in the normal range after removal of arterial baroreceptors. What is the main finding and its importance? Despite longer inspiration observed in SAD rats, the respiratory-sympathetic coupling is working within a normal range of variation...
June 22, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28639172/influence-of-cannulation-site-on-carotid-perfusion-during-extracorporeal-membrane-oxygenation-in-a-compliant-human-aortic-model
#18
Andreas Geier, Andreas Kunert, Günter Albrecht, Andreas Liebold, Markus Hoenicka
Blood oxygenized by veno-arterial extracorporeal membrane oxygenation (ECMO) can be returned to the aorta (central cannulation) or to peripheral arteries (axillar, femoral). Hemodynamic effects of these cannulation types were analyzed in a mock loop with an aortic model representative of normal anatomy and compliance under physiological pressures and flow rates. Pressures, flow rates, and contribution of ECMO flow to total flow as a measure of oxygen supply were monitored in the carotids. Steady or pulsatile ECMO flow, residual or no cardiac output, and intraaortic balloon pump counterpulsation were tested as independent factors...
June 21, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28633904/clinical-characteristics-of-type-a-acute-aortic-dissection-with-symptom-of-the-central-nervous-system
#19
Yuji Shono, Tomohiko Akahoshi, Satomi Mezuki, Kenta Momii, Noriyuki Kaku, Jun Maki, Kentaro Tokuda, Tetsuro Ago, Takanari Kitazono, Yoshihiko Maehara
BACKGROUND AND PURPOSE: Accurate diagnosis of acute aortic dissection (AAD) is sometimes difficult because of accompanying central nervous system (CNS) symptoms. The purpose of this study was to investigate the clinical characteristics of Type A AAD (TAAAD) with CNS symptoms. METHODS: We retrospectively reviewed the medical records of 8403 patients ambulanced to our emergency and critical care center between April 2009 and May 2014. RESULTS: We identified 59 TAAAD patients for the analysis (mean age, 67...
June 6, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28631107/non-invasive-coronary-wave-intensity-analysis
#20
Christopher J Broyd, Fausto Rigo, Justin Davies
Wave intensity analysis is calculated from simultaneously acquired measures of pressure and flow. Its mathematical computation produces a profile that provides quantitative information on the energy exchange driving blood flow acceleration and deceleration. Within the coronary circulation it has proven most useful in describing the wave that originates from the myocardium and that is responsible for driving the majority of coronary flow, labelled the backward decompression wave. Whilst this wave has demonstrated valuable insights into the pathogenic processes of a number of disease states, its measurement is hampered by its invasive necessity...
July 2017: International Journal of Cardiovascular Imaging
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