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https://www.readbyqxmd.com/read/28230611/values-for-bony-acetabular-roof-angle-and-percentage-femoral-head-cover-in-a-selective-ultrasound-neonatal-hip-screening-programme-effect-of-age-sex-and-side
#1
A Graham Wilkinson, Sally Wilkinson, Robert A Elton
Published maturation curves for bony acetabular roof or α angle (AA) and percentage femoral head cover (FHC) with age are sparse. We aimed to determine typical values for AA and FHC in 2236 infants referred to a selective ultrasound screening programme. There was increase in the values of first measurement of AA and FHC related to the logarithm of age. Males had greater values than females (P<0.001) and right hips had greater values than left (P<0.001) for both measurements. Significant side differences have not been reported previously...
February 22, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28229983/establishment-and-application-of-early-risk-stratification-method-for-acute-abdominal-pain-in-adults
#2
Yu Wang, Hong Zhao, Zhen Zhou, Ci Tian, Hong-Li Xiao, Bao-En Wang
BACKGROUND: Acute abdominal pain is a common symptom of emergency patients. The severity was always evaluated based on physicians' clinical experience. The aim of this study was to establish an early risk stratification method (ERSM) for addressing adults with acute abdominal pain, which would guide physicians to take appropriate and timely measures following the established health-care policies. METHODS: In Cohort 1, the records of 490 patients with acute abdominal pain that developed within the past 72 h were enrolled in this study...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28227310/analysis-of-glottal-source-parameters-in-parkinsonian-speech
#3
Jane Hanratty, Catherine Deegan, Mary Walsh, Barry Kirkpatrick, Jane Hanratty, Catherine Deegan, Mary Walsh, Barry Kirkpatrick, Mary Walsh, Barry Kirkpatrick, Jane Hanratty, Catherine Deegan
Diagnosis and monitoring of Parkinson's disease has a number of challenges as there is no definitive biomarker despite the broad range of symptoms. Research is ongoing to produce objective measures that can either diagnose Parkinson's or act as an objective decision support tool. Recent research on speech based measures have demonstrated promising results. This study aims to investigate the characteristics of the glottal source signal in Parkinsonian speech. An experiment is conducted in which a selection of glottal parameters are tested for their ability to discriminate between healthy and Parkinsonian speech...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225800/the-risk-of-disabling-surgery-and-reoperation-in-crohn-s-disease-a-decision-tree-based-approach-to-prognosis
#4
Cláudia Camila Dias, Pedro Pereira Rodrigues, Samuel Fernandes, Francisco Portela, Paula Ministro, Diana Martins, Paula Sousa, Paula Lago, Isadora Rosa, Luis Correia, Paula Moura Santos, Fernando Magro
INTRODUCTION: Crohn's disease (CD) is a chronic inflammatory bowel disease known to carry a high risk of disabling and many times requiring surgical interventions. This article describes a decision-tree based approach that defines the CD patients' risk or undergoing disabling events, surgical interventions and reoperations, based on clinical and demographic variables. MATERIALS AND METHODS: This multicentric study involved 1547 CD patients retrospectively enrolled and divided into two cohorts: a derivation one (80%) and a validation one (20%)...
2017: PloS One
https://www.readbyqxmd.com/read/28222599/petal-inspired-diffractive-grating-on-a-wavy-surface-deterministic-fabrications-and-applications-to-colorizations-and-led-devices
#5
Kyung Jin Park, Jae Hoon Park, Ji-Hyeok Huh, Chan Ho Kim, Dong Hae Ho, Gwan H Choi, Pil J Yoo, Sung Min Cho, Jeong Ho Cho, Seungwoo Lee
Interestingly, the petals of flowering plants display unique hierarchical structures, in which surface relief gratings (SRGs) are conformably coated on a curved surface with a large radius of curvature (hereafter referred to as wavy surface). However, systematic studies on the interplay between the diffractive modes and the wavy surface have not yet been reported, due to the absence of deterministic nanofabrication methods capable of generating combinatorially diverse SRGs on a wavy surface. Here, by taking advantage of the recently developed nanofabrication composed of evaporative assembly and photofluidic holography inscription, we were able to achieve (i) combinatorially diverse petal-inspired SRGs with controlled curvatures, periodicities, and dimensionalities, and (ii) systematic optical studies of the relevant diffraction modes...
February 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28222018/analytical-performance-and-diagnostic-accuracy-of-six-different-faecal-calprotectin-assays-in-inflammatory-bowel-disease
#6
Matthijs Oyaert, An Boel, Julie Jacobs, Stefanie Van den Bremt, Maxime De Sloovere, Hilde Vanpoucke, Lieve Van Hoovels
BACKGROUND: We evaluated the analytical performance of six different faecal calprotectin immunoassays together with their diagnostic accuracy in the discrimination between functional and organic bowel disorders. METHODS: The faecal samples were obtained from inflammatory bowel disease patients (n=27) at the time of diagnosis [Crohn's disease (n=15), colitis ulcerosa (n=12)], gastroenterologic disease control patients (n=52) and rheumatologic disease control patients (n=26)...
February 21, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28221191/the-assessment-of-estrogen-receptor-status-and-its-intratumoral-heterogeneity-in-breast-cancer-patients-by-using-18-f-fluoroestradiol-pet-ct
#7
Zhongyi Yang, Yifei Sun, Xiaoping Xu, Yongping Zhang, Jianping Zhang, Jing Xue, Mingwei Wang, Huiyu Yuan, Silong Hu, Wei Shi, Beiling Zhu, Yingjian Zhang
AIM: The aim of this study was to investigate the clinical value of F-fluoroestradiol (F-FES) PET/CT in the assessment of the estrogen receptor (ER) and its intratumoral heterogeneity in breast cancer patients. METHODS: Forty-six female patients (50 lesions) with histologically confirmed invasive breast cancer who underwent both F-FES and F-FDG PET/CT in our center were retrospectively included. All the patients enrolled were scheduled to undergo biopsy. The F-FES and FDG uptakes were compared with pathological features (tumor size, ER, progesterone receptor, human epidermal growth factor receptor 2, and Ki67%)...
February 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28219209/-value-of-99-tc-m-mdp-spect-ct-in-clinical-decision-making-for-nasopharyngeal-carcinoma-and-a-comparison-of-the-values-of-different-imaging-techniques-for-diagnosing-skull-base-bone-invasion
#8
W Li, R S Zhang, L Q Zhang, B G Lu, W H Fu
Objective: To analyze the clinical value of SPECT/CT in diagnosis of skull base bone invasion and clinical decision-making for nasopharyngeal carcinoma (NPC), and to compare their diagnostic value with SPECT/CT, CT, MRI, and MRI combined with SPECT (MRI-SPECT) for skull base bone invasion. Methods: Before treatment, among 348 newly diagnosed NPC patients, CT scan was performed in 186 patients (group A) and the remaining 162 patients received MRI scan (group B). Clinical doctors then made clinical management decisions according to the CT or MRI results...
February 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28218211/a-model-predicting-lymph-node-status-for-patients-with-clinical-stage-t1an0-2m0-nonsmall-cell-lung-cancer
#9
Ruo-Chuan Zang, Bin Qiu, Shu-Geng Gao, Jie He
BACKGROUND: Lymph node status of patients with early-stage nonsmall cell lung cancer has an influence on the choice of surgery. To assess the lymph node status more correspondingly and accurately, we evaluated the relationship between the preoperative clinical variables and lymph node status and developed one model for predicting lymph node involvement. METHODS: We collected clinical and dissected lymph node information of 474 patients with clinical stage T1aN0-2M0 nonsmall cell lung cancer (NSCLC)...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28216720/biostatistics-series-module-7-the-statistics-of-diagnostic-tests
#10
Avijit Hazra, Nithya Gogtay
Crucial therapeutic decisions are based on diagnostic tests. Therefore, it is important to evaluate such tests before adopting them for routine use. Although things such as blood tests, cultures, biopsies, and radiological imaging are obvious diagnostic tests, it is not to be forgotten that specific clinical examination procedures, scoring systems based on physiological or psychological evaluation, and ratings based on questionnaires are also diagnostic tests and therefore merit similar evaluation. In the simplest scenario, a diagnostic test will give either a positive (disease likely) or negative (disease unlikely) result...
January 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28212883/nonlinear-relationship-between-extreme-temperature-and-mortality-in-different-temperature-zones-a-systematic-study-of-122-communities-across-the-mainland-of-china
#11
Chenzhi Wang, Zhao Zhang, Maigeng Zhou, Lingyan Zhang, Peng Yin, Wan Ye, Yi Chen
BACKGROUND: Numerous previous studies have reported that human health risk is extremely sensitive to temperature. Very few studies, however, have characterized the relationship between temperature and mortality in different temperature zones due to the previous conclusions deduced from a regional or administrative division. A research covers different temperature zones was indispensable to have a comprehensive understanding of regional ambient temperature effect on public health. METHODS: Based on the mortality dataset and meteorological variables of 122 communities in China from 2007 to 2012, a distributed lag nonlinear model (DLNM) was utilized to estimate the temperature effect on non-accidental mortality at the community level...
February 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28212555/construction-of-a-pathological-risk-model-of-occult-lymph-node-metastases-for-prognostication-by-semi-automated-image-analysis-of-tumor-budding-in-early-stage-oral-squamous-cell-carcinoma
#12
Nicklas Juel Pedersen, David Hebbelstrup Jensen, Giedrius Lelkaitis, Katalin Kiss, Birgitte Charabi, Lena Specht, Christian von Buchwald
It is challenging to identify at diagnosis those patients with early oral squamous cell carcinoma (OSCC), who have a poor prognosis and those that have a high risk of harboring occult lymph node metastases. The aim of this study was to develop a standardized and objective digital scoring method to evaluate the predictive value of tumor budding. We developed a semi-automated image-analysis algorithm, Digital Tumor Bud Count (DTBC), to evaluate tumor budding. The algorithm was tested in 222 consecutive patients with early-stage OSCC and major endpoints were overall (OS) and progression free survival (PFS)...
February 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/28212440/emergent-inequality-and-self-organized-social-classes-in-a-network-of-power-and-frustration
#13
Benoit Mahault, Avadh Saxena, Cristiano Nisoli
We propose a simple agent-based model on a network to conceptualize the allocation of limited wealth among more abundant expectations at the interplay of power, frustration, and initiative. Concepts imported from the statistical physics of frustrated systems in and out of equilibrium allow us to compare subjective measures of frustration and satisfaction to collective measures of fairness in wealth distribution, such as the Lorenz curve and the Gini index. We find that a completely libertarian, law-of-the-jungle setting, where every agent can acquire wealth from or lose wealth to anybody else invariably leads to a complete polarization of the distribution of wealth vs...
2017: PloS One
https://www.readbyqxmd.com/read/28210230/acute-mental-discomfort-associated-with-suicide-behavior-in-a-clinical-sample-of-patients-with-affective-disorders-ascertaining-critical-variables-using-artificial-intelligence-tools
#14
Susana Morales, Jorge Barros, Orietta Echávarri, Fabián García, Alex Osses, Claudia Moya, María Paz Maino, Ronit Fischman, Catalina Núñez, Tita Szmulewicz, Alemka Tomicic
AIM: In efforts to develop reliable methods to detect the likelihood of impending suicidal behaviors, we have proposed the following. OBJECTIVE: To gain a deeper understanding of the state of suicide risk by determining the combination of variables that distinguishes between groups with and without suicide risk. METHOD: A study involving 707 patients consulting for mental health issues in three health centers in Greater Santiago, Chile. Using 345 variables, an analysis was carried out with artificial intelligence tools, Cross Industry Standard Process for Data Mining processes, and decision tree techniques...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28208227/integrating-remotely-sensed-fires-for-predicting-deforestation-for-redd
#15
Dolors Armenteras, Cerian Gibbes, Jesús A Anaya, Liliana M Dávalos
Fire is an important tool in tropical forest management, as it alters forest composition, structure, and the carbon budget. The United Nations program on Reducing Emissions from Deforestation and Forest Degradation (REDD+) aims to sustainably manage forests, as well as conserve and enhance their carbon stocks. Despite the crucial role of fire management, decision-making on REDD+ interventions fails to systematically include fires. Here, we address this critical knowledge gap in two ways. First, we review REDD+ projects and programs to assess the inclusion of fires in monitoring, reporting and verification (MRV) systems...
February 16, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28207726/long-term-survival-following-diabetic-vitrectomy
#16
Bia Z Kim, Kuo-Luong Lee, Stephen J Guest, David Worsley
AIM: To update long-term survival data on patients with proliferative diabetic retinopathy undergoing vitrectomy and to identify associated risk factors. METHODS: Retrospective clinical record review at a single New Zealand tertiary referral centre. A total of 182 eyes that underwent a vitrectomy for a diabetic vitreous haemorrhage and/or tractional retinal detachment between March 2000 and December 2010 were included. Kaplan-Meier survival curves and Cox-regression analyses were performed for survival rates and associated risk factors...
February 17, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28206966/impact-of-dna-repair-gene-polymorphisms-on-the-risk-of-biochemical-recurrence-after-radiotherapy-and-overall-survival-in-prostate-cancer
#17
Chiara Zanusso, Roberto Bortolus, Eva Dreussi, Jerry Polesel, Marcella Montico, Erika Cecchin, Sara Gagno, Flavio Rizzolio, Mauro Arcicasa, Giacomo Novara, Giuseppe Toffoli
The identification of biomarkers of biochemical recurrence (BCR) in prostate cancer (PCa) patients undergoing radiotherapy (RT) represents an unanswered clinical issue. The primary aim of this study was the definition of new genetic prognostic biomarkers in DNA repair genes (DRGs), considering both BCR and overall survival (OS) as clinical end-points. The secondary aim was to explore the potential clinical impact of these genetic variants with the decision curve analysis (DCA) and the sensitivity analysis.We analyzed 22 germline polymorphisms in 14 DRGs on 542 Caucasian PCa patients treated with RT as primary therapy...
February 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28206819/norrisk-2-a-norwegian-risk-model-for-acute-cerebral-stroke-and-myocardial-infarction
#18
Randi Selmer, Jannicke Igland, Inger Ariansen, Aage Tverdal, Inger Njølstad, Kari Furu, Grethe S Tell, Tor Ole Klemsdal
Background Guidelines for the prevention of cardiovascular disease recommend the estimation of an individual's total risk. We have developed a new model for the prediction of the 10-year risk of incident acute myocardial infarction or cerebral stroke based on Norwegian data, NORRISK 2. Design The model was based on 10-year follow-up of a large population-based cohort (CONOR) through linkage to the CVDNOR project, a database of cardiovascular disease hospital discharge diagnoses and mortality in Norway in 1994-2009...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28197696/large-meniscus-extrusion-ratio-is-a-poor-prognostic-factor-of-conservative-treatment-for-medial-meniscus-posterior-root-tear
#19
Yoon-Ho Kwak, Sahnghoon Lee, Myung Chul Lee, Hyuk-Soo Han
PURPOSE: The purpose of this study was to find a prognostic factor of medial meniscus posterior root tear (MMPRT) for surgical decision making. METHODS: Eighty-eight patients who were diagnosed as acute or subacute MMPRT without severe degeneration of the meniscus were treated conservatively for 3 months. Fifty-seven patients with MMPRT showed good response to conservative treatment (group 1), while the remaining 31 patients who failed to conservative treatment (group 2) received arthroscopic meniscus repair...
February 15, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28191344/prediction-and-diagnosis-of-non-alcoholic-fatty-liver-disease-nafld-and-identification-of-its-associated-factors-using-the-classification-tree-method
#20
Mehdi Birjandi, Seyyed Mohammad Taghi Ayatollahi, Saeedeh Pourahmad, Ali Reza Safarpour
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common form of liver disease in many parts of the world. OBJECTIVES: The aim of the present study was to identify the most important factors influencing NAFLD using a classification tree (CT) to predict the probability of NAFLD. PATIENTS AND METHODS: This cross-sectional study was conducted in Kavar, a town in the south of Fars province, Iran. A total of 1,600 individuals were selected for the study via the stratified method and multiple-stage cluster random sampling...
November 2016: Iranian Red Crescent Medical Journal
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