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Loyse Martorano Fernandes, José Cordeiro Lima Neto, Thiago Farias Rocha Lima, Marcela Baraúna Magno, Bianca Marques Santiago, Yuri Wanderley Cavalcanti, Leopoldina de Fátima Dantas de Almeida
BACKGROUND/AIMS: The evidence that mouthguards prevent dental trauma is inconsistent. The aim of this study was to determine, through a systematic review and meta-analysis (MA), the impact of mouthguards (MG) on the prevalence of dento-alveolar trauma (DT) among athletes of contact sports. MATERIAL AND METHODS: Searches were performed at Medline, Scopus, Web of Science, Lilacs, Cochrane Library and SIGLE without restriction of language or publication date. After the application of eligibity criteria, studies were evaluated regarding their methodology quality and risk of bias...
September 17, 2018: Dental Traumatology: Official Publication of International Association for Dental Traumatology
Hong Pan, Yong Bao, Honghao Cao, Rongjiang Jin, Pu Wang, Junmei Zhang
AIMS: To evaluate the value of magnetic stimulation (MS) in patients with pelvic floor dysfunction (PFD). METHODS: The Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement was followed. We searched five databases for articles published until November 2017. Included studies investigated the effects of MS on PFD. Meta-analysis of RCTs was performed using a random effects model, and narrative analysis was undertaken where meta-analysis was not possible...
September 17, 2018: Neurourology and Urodynamics
Lise J Estcourt, Reem Malouf, Carolyn Doree, Marialena Trivella, Sally Hopewell, Janet Birchall
BACKGROUND: People with thrombocytopenia often require a surgical procedure. A low platelet count is a relative contraindication to surgery due to the risk of bleeding. Platelet transfusions are used in clinical practice to prevent and treat bleeding in people with thrombocytopenia. Current practice in many countries is to correct thrombocytopenia with platelet transfusions prior to surgery. Alternatives to platelet transfusion are also used prior surgery. OBJECTIVES: To determine the clinical effectiveness and safety of prophylactic platelet transfusions prior to surgery for people with a low platelet count...
September 17, 2018: Cochrane Database of Systematic Reviews
James G Coey, Paula J Whittaker, Greg Williams, Umar H Ikram, Oliver J R Page
BACKGROUND: It has been proposed that fibrin tissue adhesive (FTA) can act as an effective alternative to nasal packing in managing the postoperative symptoms of endoscopic nasal surgery. METHODOLOGY: MEDLINE, Embase, Cochrane Library, The Cumulative Index to Nursing and Allied Health Literature and were searched for randomised controlled trials comparing FTA with nasal packing in endoscopic nasal surgery. The primary outcome of interest was bleeding; secondary outcomes included pain, nasal obstruction, infection, adhesions and the formation of granulation tissue...
September 17, 2018: Rhinology
Thomas Davergne, Adrien Pallot, Agnès Dechartres, Bruno Fautrel, Laure Gossec
OBJECTIVE: Wearable activity trackers (WATs) could be a promising strategy to improve physical activity (PA) in patients with rheumatic and musculoskeletal diseases (RMDs). The aim was to assess the adherence and effectiveness of WATs to increase PA levels in RMDs. METHODS: A systematic review was performed to identify all cohorts and controlled trials evaluating WATs in RMDs, published between 2000 and 2018, by searching MEDLINE, EMBASE, PsycINFO and Cochrane. Data collected pertained to (a) adherence, (b) effectiveness on PA or (c) effectiveness on symptoms (pain, function, quality of life or fatigue)...
September 17, 2018: Arthritis Care & Research
Jennifer Strafford Stevens, Tanja Jovanovic
Social functioning is a key component of recovery after a potentially traumatic experience, and the buffering role of the social support in trauma resilience and recovery has been very well documented. Factors contributing to resilience and recovery are notable because although most people will experience a traumatic event during their lifetimes, only 6-10% are diagnosed with post-traumatic stress disorder (PTSD). The relationship between an individual and their social environment is determined both by the quality of the social environment itself, and by the individual's perception and understanding of information conveyed by the other people around them...
September 16, 2018: Genes, Brain, and Behavior
Rachel A Johnson, Alyson Huntley, Rachael A Hughes, Helen Cramer, Katrina M Turner, Ben Perkins, Gene Feder
BACKGROUND: Hypertension (high blood pressure) is a common long-term health condition. Patient involvement in treating and monitoring hypertension is essential. Control of hypertension improves population cardiovascular outcomes. However, for an individual, potential benefits and harms of treatment are finely balanced. Shared decision making has the potential to align decisions with the preferences and values of patients. OBJECTIVE: Determine the effectiveness of interventions to support shared decision making in hypertension...
September 17, 2018: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
Shuai Wang, Jiatao Hao, Hao Wang, Yong Fang, Lijie Tan
Immune checkpoint inhibitors (ICIs) are new therapeutic strategies for non-small cell lung cancer (NSCLC). We aimed to quantitatively evaluate the efficacy and safety of ICIs in NSCLC. Pubmed, Embase, Cochrane Library, and Web of Science were searched for randomized clinical trials comparing ICIs with control therapies in NSCLC. Data were pooled according to Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. A total of 12 trails comprising 6,919 NSCLC patients were included in this meta-analysis...
2018: Oncoimmunology
Anawin Sanguankeo, Sikarin Upala
No abstract text is available yet for this article.
August 8, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Juncheol Lee, Youngsuk Cho, Kyu-Sun Choi, Wonhee Kim, Bo-Hyoung Jang, Hyungoo Shin, Chiwon Ahn, Tae Ho Lim, Hyeong-Joong Yi
OBJECTIVE: The purpose of this study was to evaluate the effects of erythropoietin (EPO) on mortality and neurological outcomes in patients with traumatic brain injury (TBI). MATERIALS AND METHODS: Electronic databases of studies published up to January 5, 2017 were searched to retrieve relevant investigations comparing the outcomes of EPO-treated patients and untreated patients following TBI. We calculated the relative risk (RR) of mortality, neurologic outcomes, and deep vein thrombosis (DVT) with corresponding 95% confidence interval (CI) using meta-analysis...
August 29, 2018: American Journal of Emergency Medicine
Jessica van Trigt, Niels Schep, Rolf Peters, Carel Goslings, Tim Schepers, Jens Halm
INTRODUCTION: There is no consensus on how pelvic X-rays should be ordered selectively in blunt trauma patients which may save time, reduce radiation exposure and costs. The aim of this systematic review and meta-analysis was to assess the need for routine pelvic X-rays in awake, respiratory and hemodynamically (HD) stable blunt trauma patients without signs of pelvic fracture. Criteria to identify patients who could safely forgo pelvic X-ray were evaluated. METHODS: A literature search was performed for prospective comparative cohort studies...
September 6, 2018: Injury
Diana P Pozuelo-Carrascosa, Ana Torres-Costoso, Celia Alvarez-Bueno, Iván Cavero-Redondo, Purificación López Muñoz, Vicente Martínez-Vizcaíno
QUESTION: In intubated adult patients receiving mechanical ventilation, does multimodality respiratory physiotherapy prevent ventilator-associated pneumonia, shorten length of intensive care unit (ICU) stay, and reduce mortality? DESIGN: A systematic review with meta-analysis of randomised controlled trials. PARTICIPANTS: Intubated adult patients undergoing mechanical ventilation who were admitted to an intensive care unit. INTERVENTION: More than two respiratory physiotherapy techniques such as positioning or postural drainage, manual hyperinflation, vibration, rib springing, and suctioning...
September 13, 2018: Journal of Physiotherapy
Na Wang, Kai Wang, Ya-Ting Liu, Fei-Xue Song
The purpose of this review was to compare the efficacy and safety of everolimus plus endocrine therapy with endocrine therapy for hormone receptor-positive, human epidermal growth factor 2 negative advanced breast cancer patients. We comprehensively searched the PubMed, the Cochrane Library, EMBASE, Web of Science, Chinese biomedicine literature database, WanFang Data, CNKI, and VIP database for relevant articles. The retrieval time limit is from building the database to July 2018. The computer search was supplemented with a manual search of reference lists for all available review articles...
September 7, 2018: Current Problems in Cancer
Lian Cui, Rongfen Chen, Smriti Subedi, Qian Yu, Yu Gong, Zeyu Chen, Yuling Shi
No abstract text is available yet for this article.
September 13, 2018: International Immunopharmacology
Harry Karna, Jaime Gonzalez, Harveen S Radia, Parish P Sedghizadeh, Reyes Enciso
The purpose of this systematic review with meta-analysis was to assess the effectiveness of dental interventions in preventing or reducing the incidence of medication-related osteonecrosis of the jaw (MRONJ) in cancer patients receiving antiresorptive therapy, compared to similar control groups receiving no intervention. Randomized controlled trials (RCT), case-controls and cohorts on cancer patients with primary outcome being the prevalence of MRONJ were included. Four electronic databases were searched (Cochrane Library, PubMed, EMBASE and Web of Science) up to February 12, 2018...
October 2018: Oral Oncology
He-Xiang Zong, Sheng-Qian Xu, Hui Tong, Xin-Rong Wang, Mei-Juan Pan, Yu-Zhu Teng
BACKGROUND: Efficacy of anti-tumor necrosis factor (anti-TNF)α treatment in patient with active ankylosing spondylitis (AS) had been proved by many clinical studies. Inflammation and new bone formation in spine were two pivotal aspects in AS. TNF α inhibitor could eliminate inflammation including clinical and laboratory inflammatory manifestation. Paradoxical results whether TNF α antagonist could delay radiographic progression in AS were often been reported simultaneously. OBJECTIVES: To review literature about effect of TNF α inhibitor on radiographic progression and disease activity in patient with AS...
September 15, 2018: Modern Rheumatology
L H Lau, J Lew, K Borschmann, V Thijs, E I Ekinci
BACKGROUND: Diabetes Mellitus is an established risk factor for stroke and maybe associated with poorer outcomes following stroke. OBJECTIVE: The aims of this literature review were to determine (i) the prevalence of diabetes in acute stroke patients through a meta-analysis, (ii) the association between diabetes and outcomes after ischemic and hemorrhagic stroke and (iii) to review the value of HbA1c and admission glucose based tests in predicting stroke outcomes...
September 16, 2018: Journal of Diabetes Investigation
Sascha Karunaratne, Michael Duan, Evangelos Pappas, Brett Fritsch, Richard Boyle, Sanjeev Gupta, Paul Stalley, Mark Horsley, Daniel Steffens
PURPOSE: The purpose of the study is to determine the effectiveness of semi-active and active robotic hip and knee arthroplasty on post-operative patient-reported outcomes of function, pain, quality of life and satisfaction with surgery. METHODS: PubMed, Medline, Embase and CENTRAL were searched. Included were comparative studies investigating the effectiveness of semi-active or active robotic hip or knee arthroplasty compared to any other surgical intervention on function, pain, quality of life and satisfaction with surgery...
September 15, 2018: International Orthopaedics
Sajjad Moradi, Atieh Mirzababaei, Alireza Dadfarma, Shahabeddin Rezaei, Hamed Mohammadi, Behrooz Jannat, Khadijeh Mirzaei
PURPOSE: Research into the relationship between food insecurity and weight abnormality has yielded varied and contradictory results. Therefore, a systematic review and meta-analysis were carried out to examine the association between food insecurity and weight abnormality in adults. METHODS: Pertinent studies were identified by searching PubMed and Scopus databases, up to February 2018. Data were available from 31 studies. These studies were conducted in 14 different countries...
September 15, 2018: European Journal of Nutrition
Sarah King, Daniel Tancredi, Irene Lenoir-Wijnkoop, Kelsie Gould, Hailey Vann, Grant Connors, Mary Ellen Sanders, Jeffrey A Linder, Andi L Shane, Dan Merenstein
Background: Overall reduction of antibiotic use is a widely adopted public health goal. Given evidence that consuming probiotics reduce the incidence, duration and/or severity of certain types of common acute infections, we hypothesized that probiotics are associated with reduced antibiotic use. This systematic review of randomized controlled trials (RCTs) assessed the impact of probiotic supplementation (any strain, dose or duration), compared to placebo, on antibiotic utilization for common, acute infections in otherwise healthy people of all ages...
September 14, 2018: European Journal of Public Health
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