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https://www.readbyqxmd.com/read/28208868/female-genital-tract-involvement-in-acute-lymphoblastic-leukemia-a-rare-case-report
#1
Vikram Narang, Amit Dhiman, Bhavna Garg, Neena Sood
Female Genital Tract (FGT) involvement with hematologic neoplasms is uncommon and the hematologic malignancies which involve the female genital organs are usually non-Hodgkin's lymphoma. Involvement of the uterus and cervix with Acute Lymphoblastic Leukaemia (ALL) is extremely rare, and ovarian involvement is even rarer. We report the case of a young lady who presented with tubo-ovarian mass, excessive post-operative bleeding (post-total abdominal hystrerctomy and bilateral salpingo-oophorectomy) and was diagnosed to have ALL with blood and tissue involvement by histopathology and flow cytometry...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28204933/a-systematic-review-of-patient-reported-outcome-measures-following-transsexual-surgery
#2
REVIEW
M Barone, A Cogliandro, N Di Stefano, V Tambone, P Persichetti
BACKGROUND: The aims of our study were to identify studies that evaluated patient satisfaction after transsexual surgery, analyze existing questionnaires, and summarize their development, psychometric properties, and content. METHODS: A systematic review of the English-language literature was performed. Patient-reported outcome measures designed to assess patient satisfaction and quality of life following transsexual surgery were identified. Qualifying instruments were assessed for content and adherence to international guidelines for development and validation...
February 15, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28203239/sublingual-priming-with-a-hiv-gp41-based-subunit-vaccine-elicits-mucosal-antibodies-and-persistent-b-memory-responses-in-non-human-primates
#3
Selma Bekri, Pierre Bourdely, Carmelo Luci, Nathalie Dereuddre-Bosquet, Bin Su, Frédéric Martinon, Véronique M Braud, Irene Luque, Pedro L Mateo, Sara Crespillo, Francisco Conejero-Lara, Christiane Moog, Roger Le Grand, Fabienne Anjuère
Persistent B cell responses in mucosal tissues are crucial to control infection against sexually transmitted pathogens like human immunodeficiency virus 1 (HIV-1). The genital tract is a major site of infection by HIV. Sublingual (SL) immunization in mice was previously shown to generate HIV-specific B cell immunity that disseminates to the genital tract. We report here the immunogenicity in female cynomolgus macaques of a SL vaccine based on a modified gp41 polypeptide coupled to the cholera toxin B subunit designed to expose hidden epitopes and to improve mucosal retention...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28201724/distinct-effects-of-the-cervico-vaginal-microbiota-and-herpes-simplex-type-2-infection-on-female-genital-tract-immunology
#4
B Shannon, P Gajer, T J Yi, B Ma, M S Humphrys, J Thomas-Pavanel, L Chieza, P Janakiram, M Saunders, W Tharao, S Huibner, K Shahabi, J Ravel, R Kaul
No abstract text is available yet for this article.
February 13, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28197351/a-case-of-malignant-melanoma-of-the-uterine-cervix-with-disseminated-metastases-throughout-the-vaginal-wall
#5
Tomoko Noguchi, Nami Ota, Yasushi Mabuchi, Shigetaka Yagi, Sawako Minami, Hisako Okuhira, Yuki Yamamoto, Yasushi Nakamura, Kazuhiko Ino
Malignant melanoma (MM) in the female genital tract accounts for less than 2% of all melanomas, and the vast majority associated occur in the vulva and vagina. Primary MM of the uterine cervix is extremely rare and its prognosis is very poor. We report a case of primary MM of the cervix with dissemination throughout the vaginal wall. A 66-year-old woman presented with postmenopausal bleeding. Gynecologic examination demonstrated a 2 cm polypoid blackish-pigmented tumor on the cervix with multiple small blackish-pigmented lesions throughout the vaginal wall...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28195268/unusual-pleural-effusion-from-vulvar-squamous-cell-carcinoma-report-of-a-case-and-review-of-the-literature
#6
S Erra, G Patrucco, G Speranza, S Barbero, F Brucculeri, G Taverna
Vulvar tumors are not very common and account for about 4% of all cancers affecting the female genital organs. Frequently, malignant neoplasia of this site have squamous phenotype and the rare cases of metastasization are reported in the locoregional lymph nodes and in the surrounding organs. We report a case of metastasization of a vulvar squamous cell carcinoma in an unusual place such as the parietal pleura, in a relapsing patient that was submitted to a surgical vulvectomy the previous year.
September 2016: Pathologica
https://www.readbyqxmd.com/read/28192886/association-of-sleep-quality-in-behcet-disease-with-disease-activity-depression-and-quality-of-life-in-korean-population
#7
Jimin Lee, Sung-Soo Kim, Hye-Jin Jeong, Chang-Nam Son, Ji-Min Kim, Yong-Won Cho, Sang-Hyon Kim
Background/Aims: Sleep disturbance is prime concern in patients with Behcet disease. The purpose of this study was to find out the effects of sleep quality, in Korean patients suffering from Behcet disease. We further investigated the relationship between depression, quality of life and the clinical findings of Behcet disease. Methods: The study was performed by the cross-sectional design. Sleep quality was assessed by the Korean version of Pittsburgh sleep quality index (PSQI)...
February 16, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28187741/virility-pleasure-and-female-genital-mutilation-cutting-a-qualitative-study-of-perceptions-and-experiences-of-medicalized-defibulation-among-somali-and-sudanese-migrants-in-norway
#8
R Elise B Johansen
BACKGROUND: The most pervasive form of female genital mutilation/cutting-infibulation-involves the almost complete closure of the vaginal orifice by cutting and closing the labia to create a skin seal. A small opening remains for the passage of urine and menstrual blood. This physical closure has to be re-opened-defibulated-later in life. When they marry, a partial opening is made to enable sexual intercourse. The husband commonly uses his penis to create this opening. In some settings, a circumciser or traditional midwife opens the infibulated scar with a knife or razor blade...
February 10, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28187665/land-flatworms-platyhelminthes-geoplanidae-of-s%C3%A3-o-tom%C3%A3-%C3%A2-a-first-account-on-their-diversity-with-the-description-of-five-new-species
#9
Ronald Sluys, Matthias Neumann, Ricardo F DE Lima, Robert C Drewes
The present contribution provides the first faunistic and taxonomic account of six species of land flatworm from the island of São Tomé, including five new species of the genus Othelosoma Gray, 1869 and the introduced Bipalium kewense Moseley, 1878. One of the new species represents the first African land flatworm that has specks on its dorsal body surface, instead of stripes or a more or less uniform colouration. At least two of the new species were observed to prey on snails. The study details the fourth record of a sclerotic spermatophore in a species of land flatworm, and discusses the definition and homology of double female genital canals in African and Indian species of the genus Othelosoma...
January 17, 2017: Zootaxa
https://www.readbyqxmd.com/read/28187622/a-new-species-in-the-i-simulium-i-i-vernum-i-group-from-the-alps-of-southern-germany-i-simulium-i-i-arminii-i-diptera-simuliidae
#10
Gunther Seitz, Peter H Adler
Simulium arminii new species is described from the Alps of southern Germany. It is characterized by a broad trapezoidal ventral plate in the male, long slender arms of the genital fork in the female, a weakly developed or absent anterodorsal projection on the thinly woven cocoon, and a long median hypostomal tooth in the larva. The species is chromosomally similar to Simulium beltukovae (Rubtsov) but differs most conspicuously by the absence of a chromocenter. It is known from two small, springfed streams above the timber line, in association with Prosimulium latimucro (Enderlein) and Simulium bavaricum Seitz and Adler...
January 26, 2017: Zootaxa
https://www.readbyqxmd.com/read/28183228/btg3-overexpression-suppresses-the-proliferation-and-invasion-in-epithelial-ovarian-cancer-cell-by-regulating-akt-gsk3%C3%AE-%C3%AE-catenin-signaling
#11
Qi An, Yan Zhou, Chao Han, Yubing Zhou, Feng Li, Duolu Li
Epithelial ovarian cancer (EOC) is the leading cause of cancer-related death among all the gynecological malignancies of the female genital system, and its incidence and mortality rates continue to rise. B-cell translocation gene 3 (BTG3) plays an important role in the occurrence and development of numerous cancers. However, the role of BTG3 in EOC remains poorly understood. In this study, we aimed to investigate the biological role and potential molecular mechanism of BTG3 in EOC. We found that BTG3 protein expression was significantly lower in human EOC cell lines...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28180938/compound-heterozygous-gata5-mutations-in-a-girl-with-hydrops-fetalis-congenital-heart-defects-and-genital-anomalies
#12
Maja Hempel, Teresa Casar Tena, Thilo Diehl, Martina S Burczyk, Tim M Strom, Christian Kubisch, Melanie Philipp, Davor Lessel
GATA5 belongs to the GATA family of transcription factors characterized by highly evolutionarily conserved zinc-finger DNA-binding domains. Mouse models have implicated a role of GATA5 during mammalian embryogenesis, including proper heart development and gender-specific regulation of female genitourinary tract formation. Previous studies have found an association of heterozygous missense alterations in GATA5 with a broad variety of heart diseases; however, the clinical relevance of the identified susceptibility variants has remained unclear...
February 8, 2017: Human Genetics
https://www.readbyqxmd.com/read/28178983/management-of-painful-clitoral-neuroma-after-female-genital-mutilation-cutting
#13
Jasmine Abdulcadir, Jean-Christophe Tille, Patrick Petignat
BACKGROUND: Traumatic neuromas are the result of regenerative disorganized proliferation of the proximal portion of lesioned nerves. They can exist in any anatomical site and are responsible for neuropathic pain. Post-traumatic neuromas of the clitoris have been described as an uncommon consequence of female genital mutilation/cutting (FGM/C). FGM/C involves partial or total removal of the female genital organs for non-therapeutic reasons. It can involve cutting of the clitoris and can cause psychological, sexual, and physical complications...
February 8, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28178893/sexually-transmitted-infection-prevalence-and-related-risk-factors-among-heterosexual-male-methamphetamine-users-in-china
#14
Dianchang Liu, Zhenxia Jiang, Cuizhen Xiu, Zhizhi Li, Qing Song, Zhenhong Wang
Few studies have examined the association between methamphetamine (MA) abuse and sexually transmitted infection (STI) risk among heterosexual male MA users in China. A total of 288 heterosexual male MA users who met our inclusion criteria were recruited from nightclubs, KTVs, bars, bath centres and an STI clinic. STIs were screened among the participants, and the risk factors related to STIs were analysed by multivariate logistic regression in SPSS 11.0. Among the 288 heterosexual male MA users, 51 (17.7%) had syphilis, 36 (12...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28177977/research-disparities-in-female-to-male-transgender-genital-reconstruction-the-charge-for-high-quality-data-on-patient-reported-outcome-measures
#15
Jordan D Frey, Grace Poudrier, Michael V Chiodo, Alexes Hazen
No abstract text is available yet for this article.
March 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28173865/stage-1-embryonal-rhabdomyosarcoma-of-the-female-genital-tract-a-retrospective-clinical-study-of-nine-cases
#16
Guangwen Yuan, Hongwen Yao, Xiaoguang Li, Hongjun Li, Lingying Wu
BACKGROUND: The aim of the study is to investigate the clinical features, treatments, and prognosis of stage 1 embryonal rhabdomyosarcoma of the female genital tract. METHODS: A retrospective analysis was performed on nine cases of stage 1 embryonal rhabdomyosarcoma of the female genital tract. Clinical characteristics, treatments, recurrence, and prognosis were analyzed. RESULTS: Of the nine patients with embryonal rhabdomyosarcoma, three originated from the vagina and six from the cervix...
February 7, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28173770/screening-for-genital-tuberculosis-in-a-limited-resource-country-case-report
#17
Sadie Namani, Emine Qehaja-Buçaj, Diellëza Namani
BACKGROUND: Screening for benign or malignant process of pelvis in young females is a challenge for a physician in a limited resource country. Tuberculosis should be always considered in the differential diagnosis of a pelvic mass in countries with high prevalence of tuberculosis. Negative results of analysis of peritoneal fluid for acid-fast staining, late cultures, and unavailability of new diagnostics methods such as polymerase chain reaction and adenosine deaminase of the aspirated fluid from peritoneal cavity can often result in invasive diagnostic procedures such as laparotomy...
February 7, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28169372/copulatory-courtship-by-internal-genitalia-in-bushcrickets
#18
Nadja C Wulff, Thomas van de Kamp, Tomy Dos Santos Rolo, Tilo Baumbach, Gerlind U C Lehmann
Male genital organs are among the fastest evolving morphological structures. However, large parts of the male's genitalia are often hidden inside the female during mating. In several bushcricket species, males bear a pair of sclerotized genital appendices called titillators. By employing synchrotron-based in vivo X-ray cineradiography on mating couples, we were able to visualize titillator movement and spermatophore attachment inside the female. Titillators are inserted and retracted rhythmically. During insertion the titillator processes tap the soft and sensillae-covered dorsal side of the female's flap-like genital fold, which covers the opening of the female's genitalia, without tissue penetration...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28166736/prevalence-and-incidence-of-external-genital-warts-in-a-sample-of-italian-general-female-population
#19
Barbara Suligoi, Giorgio Vittori, Maria Cristina Salfa, Laura Timelli, Dario Corsini, Giovanni Fattorini, Luciano Mariani
BACKGROUND: The Human papillomavirus is the most common sexually transmitted virus worldwide. The objective of this study was to estimate: 1) the prevalence and the incidence of external genital warts (eGW) in a sample of women attending community outpatient clinics and 2) the total number of eGW cases in the Italian female population aged 15-64 years. METHODS: A prospective study was performed for a 12-month period between 2009 and 2010, among a sample of women attending community gynecological outpatient clinics located throughout Italy...
February 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28166073/ovarian-tumors-pattern-of-histomorphological-types-a-10-years-study-in-a-tertiary-referral-center-and-review-of-literature
#20
A Ghosh, D Ghartimagar, S Thapa, B Sathian, R Narasimhan, O P Talwar
Background Ovarian cancer accounts for 6% of all cancers in females. Among cancers of female genital tract, the incidence of ovarian cancers ranks below only carcinoma of the cervix and the endometrium. Objective To find the frequency of different types of histomorphological types and their association with age, side and size distribution. Method This study is a hospital based retrospective study carried out in the Department of Pathology, Manipal Teaching Hospital over a time period from Jan. 2006 to Sep. 2015...
April 2016: Kathmandu University Medical Journal (KUMJ)
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