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https://www.readbyqxmd.com/read/30419291/a-general-theory-of-genital-homologies-for-the-hexapoda-pancrustacea-derived-from-skeletomuscular-correspondences-with-emphasis-on-the-endopterygota
#1
Brendon E Boudinot
No consensus exists for the homology and terminology of the male genitalia of the Hexapoda despite over a century of debate. Based on dissections and the literature, genital skeletomusculature was compared across the Hexapoda and contrasted with the Remipedia, the closest pancrustacean outgroup. The pattern of origin and insertion for extrinsic and intrinsic genitalic musculature was found to be consistent among the Ectognatha, Protura, and the Remipedia, allowing for the inference of homologies given recent phylogenomic studies...
November 9, 2018: Arthropod Structure & Development
https://www.readbyqxmd.com/read/30418980/low-coverage-of-hpv-vaccination-in-the-national-immunization-programme-in-brazil-parental-vaccine-refusal-or-barriers-in-health-service-based-vaccine-delivery
#2
William Mendes Lobão, Fernanda Gross Duarte, Jordan Danielle Burns, Carlos Antonio de Souza Teles Santos, Maria Conceição Chagas de Almeida, Arthur Reingold, Edson Duarte Moreira
BACKGROUND: The World Health Organization has recommended the introduction of HPV vaccines into national immunization programme (NIP), but vaccination coverage remains low worldwide. We assessed the coverage and the parental acceptance of female and male HPV vaccination in Brazil after its introduction into the NIP. METHODS: We conducted a random-digit-dial survey of parents in seven major Brazilian cities from July-2015 to October-2016. A knowledge, attitude and practices questionnaire was developed and validated by expert analysis, semantic analysis, and pre-testing...
2018: PloS One
https://www.readbyqxmd.com/read/30418184/the-spectrum-of-ebv-positive-mucocutaneous-ulcer-a-study-of-9-cases
#3
Lucía Prieto-Torres, Itziar Eraña, Rocio Gil-Redondo, Inés Gómez de la Riva, Rebeca Manso, Raquel Pajares, Raúl Córdoba, Salma Machan, Mariano Ara, Luís Requena, Miguel Á Piris, Socorro M Rodríguez-Pinilla
We describe a series of 9 patients with Epstein-Barr virus (EBV)-positive mucocutaneous lymphoproliferative lesions that broadens the concept of EBV-positive mucocutaneous ulcer. We report 5 female and 4 male patients, with an average age of 74 years (range, 55 to 87 y), 2 of whom were HIV-positive. The lesions were located in the oropharynx, skin, and rectal and/or genital mucosa. Histopathologically, 6 cases showed a polymorphic pattern and 3 had a monomorphic and diffuse one, with angiotropism in 4 cases (2 each with the polymorphic and monomorphic patterns)...
November 9, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/30416981/hpv-related-cancer-prevention-and-control-programs-at-community-based-hiv-aids-service-organizations-implications-for-future-engagement
#4
Lisa T Wigfall, Shalanda A Bynum, Heather M Brandt, Neethu Sebastian, Marcia G Ory
Background: People living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and, men who have sex with men (MSM) are disproportionately affected by genital warts and cancers caused by human papillomavirus (HPV). We assessed community-based HIV/AIDS service organizations' (ASOs) staff awareness, knowledge, attitudes, and beliefs about HPV and effective cancer prevention tools, namely HPV vaccination, Pap, and HPV tests. The potential engagement of ASO staff in future efforts to reduce the disproportionate burden of genital warts and HPV-related cancers among HIV-positive women and MSM was explored...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/30412961/re-rhabdomyosarcoma-of-the-lower-female-genital-tract-an-analysis-of-144-cases
#5
Douglas A Canning
No abstract text is available yet for this article.
September 2018: Journal of Urology
https://www.readbyqxmd.com/read/30412859/development-of-disease-and-immunity-at-the-genital-epithelium-following-intrarectal-inoculation-of-male-guinea-pigs-with-herpes-simplex-virus-type-2
#6
Nigel Bourne, Brianne N Banasik, Clarice L Perry, Aaron L Miller, Mellodee White, Richard B Pyles, Gregg N Milligan
Most analyses of genital immunity to herpes simplex virus type 2 (HSV-2) have been performed in females, consequently immune protection of the male genital epithelium is incompletely understood. We developed a model of male genital HSV-2 infection resulting from intrarectal inoculation of guinea pigs. Vesicular lesions developed transiently on the perineum and foreskin concurrent with acute virus shedding. Virus shedding and recurrent genital lesions were also detected after establishment of a latent infection...
November 6, 2018: Virology
https://www.readbyqxmd.com/read/30412060/risk-of-sexually-transmitted-infections-following-depressive-disorder-a-nationwide-population-based-cohort-study
#7
Sheng-Yun Huang, Jeng-Hsiu Hung, Li-Yu Hu, Min-Wei Huang, Shyh-Chyang Lee, Cheng-Che Shen
Depressive disorder is a severe mental disorder associated with functional and cognitive impairment. Numerous papers in the literature investigated associations between sexually transmitted infections (STIs) and psychiatric illnesses. However, the results of these studies are controversial.We explored the relationship between depressive disorder and the subsequent development of STIs including human immunodeficiency virus (HIV) infection, primary, secondary, and latent syphilis, genital warts, gonorrhea, chlamydial infection, and trichomoniasis...
October 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30411652/from-sameness-to-difference-swedish-somalis-post-migration-perceptions-of-the-circumcision-of-girls-and-boys
#8
Anna Wahlberg, Birgitta Essén, Sara Johnsdotter
In every society where non-therapeutic female circumcision (FC) occurs, so too does non-therapeutic male circumcision (MC). In the past few decades, the norm in Euro-American societies has been to distinguish between the practices: FC is banned, while MC is condoned or encouraged. We explored Somalis' post-migration perceptions of FC and MC, while considering that they once lived in a society where both practices were widely accepted and now live in a society where there is a legal ban on FC alongside acceptance of MC...
November 9, 2018: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/30406341/blue-light-emitting-diode-in-healthy-vaginal-mucosa-a-new-therapeutic-possibility
#9
Maria Clara Pavie, Mariana Robatto, Milena Bastos, Sibele Tozetto, Andrea Vilas Boas, Salvatore Giovanni Vitale, Patrícia Lordelo
A healthy female genital mucosa has an ecosystem that remains in balance through interactions between endogenous and exogenous factors. The light-emitting diode (LED) is a device that emits light at different wavelengths, with varying color and effects. Blue light in humans is most commonly used for antimicrobial purposes and has been already applied to treat facial acne and gastric bacteria. Although blue LED therapy in humans has been reported, its properties against vaginal infections have not yet been investigated...
November 7, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/30402135/bu-shen-yang-xue-prescription-has-treating-effect-on-endometrial-cancer-through-fsh-pi3k-akt-gankyrin-hif-%C3%AE-cyclind-1-pathway-in-ishikawa-cells
#10
Yue-Qun Chen, Hua-Li Fei, Hong-Li Zhu
Background. The formulation of Bu Shen Yang Xue (BSYX) has been clinically used in treating gynecologic disease in China, especially for the development of the endometrium. Endometrial carcinoma is the most common malignant tumor of the female genital tract in developed countries. And few studies have been reported on the antitumor activity of BSYX. Therefore, this study aimed to investigate the effect of BSYX on endometrial cancer and make an initial discussion of the underlining mechanisms in Ishikawa cells...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/30399181/the-lived-experience-of-female-genital-cutting-fgc-in-somali-canadian-women-s-daily-lives
#11
Danielle Jacobson, Emily Glazer, Robin Mason, Deanna Duplessis, Kimberly Blom, Janice Du Mont, Navmeet Jassal, Gillian Einstein
Many of the Somali women who have immigrated to other countries, including Canada, have experienced Female Genital Circumcision/ Mutilation/ Cutting (FGC). While there is literature on the medical aspects of FGC, we were interested in understanding the daily life experiences and bodily sensations of Somali-Canadian women in the context of FGC. Fourteen women living in the Greater Toronto Area were interviewed. Interview data were analyzed using a phenomenological approach. We found that the memory of the ceremonial cutting was vivid but was frequently described with acceptance and resignation-as something that just is; that was normal given the particular context, familial and cultural, and their young age...
2018: PloS One
https://www.readbyqxmd.com/read/30397742/management-and-survival-trends-for-adult-patients-with-malignant-gliomas-in-the-setting-of-multiple-primary-tumors-a-population-based-analysis
#12
Ha Son Nguyen, Ninh B Doan, Michael Gelsomino, Saman Shabani, Ahmed J Awad, Mayank Kaushal, Martin M Mortazavi
INTRODUCTION: The impact of multiple primary tumors, in the setting of malignant glioma (MG), has not been heavily explored. METHODS: We extracted demographics and clinical data from the SEER-18 registry for adult patients with MGs. The cases were separated based on the sequence of MG diagnosis relative to the other primary tumors: Group (A) One primary only or first primary of multiple primaries and Group (B) second primary or subsequent primary tumor. Incidences, frequencies, and glioma-related survivals were analyzed...
November 5, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/30396319/burden-of-genital-warts-in-peru-an-observational-study
#13
Patricia J García, Cesar P Carcamo, Maria Valderrama, Sayda La Rosa, Cerise James, Raul Gutiérrez, Brianna R Lindsay
Genital warts (GW) are mucosal or skin lesions caused by sexual transmission of human papillomavirus (HPV). This study estimates the frequency of GW cases in physicians' clinics and physicians' usual practices of GW referral and diagnosis in Peru. Participants in this study were a convenience sample of 100 physicians in five specialties: primary care (17), gynecology (37), urology (10), dermatology (31), and infectious diseases (5). Physicians completed a survey and daily log of all patients aged 18-60 years seen over ten days in their offices located in Peru...
November 5, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/30388241/psychosexual-aspects-effects-of-prenatal-androgen-exposure-and-gender-change-in-46-xy-disorders-of-sex-development
#14
Rafael Loch Batista, Marlene Inácio, Ivo José P Arnhold, Nathália Lisboa Gomes, José Antônio Faria, Daniela Rodrigues de Moraes, Elaine Maria Frade Costa, Sorahia Domenice, Berenice Bilharinho de Mendonca
Background: In 46,XY DSD patients, several factors may affect psychosexual development, leading to gender identity discrepancy and gender change later in life. Prenatal sexual steroid exposure and external genital virilization are considered to influence human psychosexual development, but it is not completely understood yet. Methods: A total of 144 individuals (18-60 years) with a clinical/molecular diagnosis of 46,XY DSD from a single tertiary center were enrolled...
November 1, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30383612/potential-diagnostic-pitfalls-in-evaluating-immunohistochemistry-for-cervical-myofibroblastomas
#15
Sharon Song, Amy Ziober, Kumarasen Cooper
Cervicovaginal myofibroblastoma (CVM) is a rare benign mesenchymal tumor of the lower female genital tract that shows chromosomal loss of 13q14 (RB1 gene located in this region). The aim of this study was to investigate the utility of immunohistochemistry (IHC) for desmin, CD34, and Rb in diagnosing CVM. All cervical polyps diagnosed from July 2016 to July 2017 were retrospectively reviewed. Cases showing morphologic myofibroblastic differentiation were evaluated by IHC for desmin, CD34, and Rb. Desmin and CD34 staining was recorded as positive or negative...
October 31, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/30383609/tubulovillous-adenoma-of-vagina-with-both-kras-and-apc-mutations-case-report
#16
Somruetai Shuangshoti, Chinachote Teerapakpinyo
Adenomatous polyps of the vulva and vagina are extremely rare. We report a case of a 74-yr-old women with a tubulovillous adenoma occurring in the vagina, and a second one occurring later in the vulva. Tumor cells in both lesions were CK7, CK20, CDX-2, and showed intact mismatch-repair proteins. A G13D (c.38G>A, p.Gly13Asp) mutation in the KRAS gene was identified in both masses. As well, a novel frameshift truncating mutation (c.4320delA, p.Pro1441fsTer32) in the APC gene was detected only in the vaginal mass, ruling out the possibility that the vulvar mass was a local recurrence of the vaginal mass...
October 31, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/30381486/metagenomic-sequencing-of-hiv-1-in-the-blood-and-female-genital-tract-reveals-little-quasispecies-diversity-during-acute-infection
#17
Anne Piantadosi, Catherine A Freije, Christina Gosmann, Simon Ye, Daniel Park, Stephen F Schaffner, Damien C Tully, Todd M Allen, Krista L Dong, Pardis C Sabeti, Douglas S Kwon
Heterosexual transmission of human immunodeficiency virus-1 (HIV-1) is associated with a significant bottleneck in the viral quasispecies population, yet the timing of that bottleneck is poorly understood. We characterized HIV-1 diversity in the blood and female genital tract (FGT) within two weeks after detection of infection in three women enrolled in a unique prospective cohort in South Africa. We assembled full-length HIV-1 genomes from matched samples of cervicovaginal lavage (CVL) and plasma. Deep sequencing allowed us to identify intrahost single nucleotide variants (iSNVs) and characterize within-sample HIV-1 diversity...
October 31, 2018: Journal of Virology
https://www.readbyqxmd.com/read/30374843/autotaxin-is-a-novel-molecular-identifier-of-type-i-endometrial-cancer
#18
Antonio Mazzocca, Luca Maria Schönauer, Rosalba De Nola, Antonio Lippolis, Teresa Marrano, Matteo Loverro, Carlo Sabbà, Edoardo Di Naro
Endometrial cancer is the most common cancer of the female genital tract in Western Countries, with an incidence of 150.000 new cases/year. Despite high incidence, little is known about the molecular pathogenesis of this tumor. Phospholipids including lysophosphatidic acid (LPA) are involved in proliferation and dissemination of cancer. LPA is a potent bioactive phospholipid synthesized by autotaxin (ATX) through its lysophospholipase D activity. Recent evidence suggests that the ATX/LPA signaling axis plays a role in endometrial cancer...
October 29, 2018: Medical Oncology
https://www.readbyqxmd.com/read/30374684/differences-in-mortality-in-fusobacterium-necrophorum-and-fusobacterium-nucleatum-infections-detected-by-culture-and-16s-rrna-gene-sequencing
#19
Katrine M Johannesen, Shailesh B Kolekar, Nikolaos Greve, Xiaohui Chen Nielsen, Toke Seierøe Barfod, Uffe Bodtger
Fusobacterium species are components of the normal microbiota of the oral cavity, gastrointestinal tract, and female genital tract. They are increasingly recognized as causative agents of oral, laryngeal, and tonsillar infections. Several fusobacterial species are involved in infections, with F. necrophorum and F. nucleatum being the most commonly cultured subtypes. In this study, we aimed to investigate clinical and prognostic differences in terms of mortality and association with malignancy between F. necrophorum and F...
October 29, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/30371786/challenges-in-the-eradication-of-female-genital-mutilation-cutting
#20
Mary McCauley, Nynke van den Broek
No abstract text is available yet for this article.
October 29, 2018: International Health
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