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Retinal occlusion

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https://www.readbyqxmd.com/read/28739419/retinal-non-perfusion-in-the-posterior-pole-is-associated-with-increased-risk-of-neovascularization-in-central-retinal-vein-occlusion
#1
Luke Nicholson, Clara Vazquez-Alfageme, Namritha V Patrao, Ioanna Triantafyllopolou, James W Bainbridge, Philip G Hykin, Sobha Sivaprasad
PURPOSE: To review the definition of ischaemic central retinal vein occlusion (CRVO) and stratify the risk of neovascular complication based on wider areas of visible retinal non-perfusion. DESIGN: Retrospective consecutive case series and image analysis study METHODS: Setting: Moorfields Eye Hospital, London, United Kingdom. STUDY POPULATION: 42 consecutive treatment naïve eyes with CRVO imaged with ultra-widefield angiography with a minimum of 12 months follow-up...
July 21, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28734330/acute-on-chronic-retinal-artery-occlusion-following-retinal-vein-occlusion
#2
Kelly Z Young, Vaidehi S Dedania, Rajesh C Rao
No abstract text is available yet for this article.
August 2017: Ophthalmology
https://www.readbyqxmd.com/read/28732607/refractive-outcomes-and-complications-after-combined-copolymer-phakic-intraocular-lens-explantation-and-phacoemulsification-with-intraocular-lens-implantation
#3
Paolo G Meier, François Majo, Philippe Othenin-Girard, Ciara Bergin, Ivo Guber
PURPOSE: To assess safety, efficacy, and predictability of combined Implantable Collamer Lens phakic intraocular lens (pIOL) explantation and phacoemulsification and to report the rate of complications. A secondary aim was to examine whether intraocular lens (IOL) power calculation was affected by the pIOL in situ. SETTING: Jules-Gonin Eye Hospital, Lausanne, Switzerland. DESIGN: Retrospective case series. METHODS: The records of patients having pIOL implantation with subsequent phacoemulsification were reviewed...
June 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28730400/evaluation-of-retrobulbar-blood-flow-and-choroidal-thickness-in-patients-with-rheumatoid-arthritis
#4
Ali Kal, Enes Duman, Almila Sarıgül Sezenöz, Mahmut Oğuz Ulusoy, Öznur Kal
PURPOSE: To evaluate whether retrobulbar blood flow and choroidal thickness (CT) are affected in patients with rheumatoid arthritis (RA), and the relationship between these values. METHODS: We evaluated 40 eyes of 20 RA patients and 40 eyes of 20 healthy controls. The enhanced depth imaging optical coherence tomography, color Doppler imaging, was held. Statistical analysis was performed. RESULTS: Peak systolic velocity (PSV) of ophthalmic (OA) and central retinal artery (CRA) were significantly higher in RA...
July 20, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28730399/optical-coherence-tomography-angiography-findings-in-susac-s-syndrome-a-case-report
#5
Rodolfo Mastropasqua, Lisa Toto, Alfonso Senatore, Alessandro D'Uffizi, Piergiorgio Neri, Cesare Mariotti, Marica Tina Maccarone, Luca Di Antonio
PURPOSE: To report clinical features of Susac's syndrome (SS) using optical coherence tomography angiography (OCTA). METHODS: Case report. RESULTS: A 25-year-old Caucasian female with a history of non-pulsatile migraine, tinnitus, and verbal apraxia complaining of peripheral scotoma in left eye due to branch retinal arteriole occlusion (BRAO) was diagnosed as having SS after audiometric test, brain magnetic resonance imaging, and multimodal retinal imaging...
July 20, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28725290/the-discovery-of-the-flammer-syndrome-a-historical-and-personal-perspective
#6
REVIEW
Josef Flammer, Katarzyna Konieczka
This review describes the clinical and basic research that led to the description of Flammer syndrome. It is narrated from a personal perspective. This research was initiated by the observation of an increased long-term fluctuation of visual fields in a subgroup of glaucoma patients. As these patients had strikingly cold hands, peripheral blood flow was tested with a capillary microscopy, and vasospastic syndrome (VS) was diagnosed. Further studies on these patients revealed frequently weakened autoregulation of ocular blood flow and increased flow resistivity in retroocular vessels...
June 2017: EPMA Journal
https://www.readbyqxmd.com/read/28724817/real-world-evidence-of-safety-profile-of-intravitreal-bevacizumab-avastin-in-an-indian-scenario
#7
Prashant Jain, Jay Sheth, Giridhar Anantharaman, Mahesh Gopalakrishnan
PURPOSE: The purpose of this study was to evaluate the safety profile of intravitreal bevacizumab (Avastin) as an off-label pharmacotherapeutic agent for various ocular conditions. METHODS: Retrospective analysis was carried out on 3806 injections of 1761 patients that were administered with intravitreal bevacizumab injection at a tertiary eye care center in India. The injections were administered on a pro re nata basis for various indications such as age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vein occlusion (RVO)...
July 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28719002/eyeslam-real-time-simultaneous-localization-and-mapping-of-retinal-vessels-during-intraocular-microsurgery
#8
Daniel Braun, Sungwook Yang, Joseph N Martel, Cameron N Riviere, Brian C Becker
BACKGROUND: Fast and accurate mapping and localization of the retinal vasculature is critical to increasing the effectiveness and clinical utility of robot-assisted intraocular microsurgery such as laser photocoagulation and retinal vessel cannulation. METHODS: The proposed EyeSLAM algorithm delivers 30 Hz real-time simultaneous localization and mapping of the human retina and vasculature during intraocular surgery, combining fast vessel detection with 2D scan-matching techniques to build and localize a probabilistic map of the vasculature...
July 18, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/28711869/establishment-of-a-retinal-hypoxia-organ-culture-model
#9
S Schnichels, M Blak, J Hurst, T Dorfi, K U Bartz-Schmidt, F Ziemssen, M S Spitzer, M Schultheiss
Hypoxia plays an important role in several retinal diseases, especially in central retinal artery occlusion (CRAO). Although CRAO has been known for over a hundred years, no cure or sufficient treatment is available. Potential therapies are being evaluated in several in vivo models or primary cultures. However, in vivo models or primary cultures are very time-consuming, expensive, and furthermore several therapies or agents cannot be tested. Therefore, we aimed to develop a standardized organotypic ex vivo retinal hypoxia model...
July 15, 2017: Biology Open
https://www.readbyqxmd.com/read/28709761/central-nervous-system-involvement-in-eosinophilic-granulomatosis-with-polyangiitis-churg-strauss-report-of-26-patients-and-review-of-the-literature
#10
REVIEW
Raphaël André, Vincent Cottin, Jean-Luc Saraux, Gilles Blaison, Boris Bienvenu, Pascal Cathebras, Romain Dhote, Aurélie Foucher, Helder Gil, Joëlle Lapoirie, David Launay, Valentine Loustau, François Maurier, Edouard Pertuiset, Thierry Zénone, Jörg Seebach, Nathalie Costedoat-Chalumeau, Xavier Puéchal, Luc Mouthon, Loïc Guillevin, Benjamin Terrier
BACKGROUND: Although peripheral nervous system involvement is common in eosinophilic granulomatosis with polyangiitis (EGPA), central nervous system (CNS) manifestations are poorly described. This study aimed to describe CNS involvement in EGPA. PATIENTS AND METHODS: This retrospective, observational, multicenter study included patients with EGPA and CNS involvement affecting cranial nerves, brain and/or spinal cord. We also undertook a systematic literature review...
July 11, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/28705840/central-retinal-artery-occlusion-in-a-30-year-old-woman-taking-tranexamic-acid
#11
Sidath Wijetilleka, Damien Chia Ming Yeo, Bhavana Sharma
We present a case of a 30-year-old woman who suffered a central retinal artery occlusion while taking tranexamic acid. She had no vascular risk factors and was placed on the drug for treatment of menorrhagia. After 1 month of taking the drug, she suffered a central retinal artery occlusion in her left eye. Tranexamic acid was discontinued to prevent vision loss in the following eye. She remains with no perception of light vision in the affected eye.
July 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28700390/bartonella-henselae-neuroretinitis-associated-with-central-retinal-vein-occlusion-choroidal-ischemia-and-ischemic-optic-neuropathy
#12
Quraish Ghadiali, Larissa K Ghadiali, Lawrence A Yannuzzi
PURPOSE: We describe a healthy 37-year-old man with Bartonella henselae (B. henselae) neuroretinitis with concurrent central retinal vein occlusion and ischemic optic neuropathy resulting in optic atrophy and choroidal ischemia. METHODS: Case report. RESULTS: A 37-year-old man presented with unilateral decreased vision and a fundus examination consistent with neuroretinitis. Further imaging review supported a concurrent diagnosis of central retinal vein occlusion...
July 11, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28700136/an-automated-framework-to-quantify-areas-of-regional-ischemia-in-retinal-vascular-diseases-with-oct-angiography
#13
Neha Anegondi, Lavanya Chidambara, Devanshi Bhanushali, Santosh G K Gadde, Naresh Kumar Yadav, Abhijit Sinha Roy
In this observational and cross-sectional study, capillary non perfusion (CNP) and vascular changes in branch retinal vein occlusion (BRVO, sample size (n) = 26) and choroidal neovascularization (CNV, n = 29) were evaluated. Subjects underwent imaging using Optical coherence tomography angiography (Angiovue™ OCTA , RTVue XR, Optovue Inc., Fremont, CA). Local fractal analysis was applied to the OCTA images of superficial, deep and choriocapillaries layer. CNP area (BRVO eyes) and vascular parameters were computed using local fractal based method...
July 12, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28695380/macular-capillary-recovery-in-systemic-lupus-erythematosus-complicated-by-kikuchi-fujimoto-disease
#14
Reiko Kinouchi, Motoshi Kinouchi, Akihiro Ishibazawa, Akitoshi Yoshida
PURPOSE: Few case reports have described vaso-occlusive retinopathy in systemic lupus erythematosus (SLE) using optical coherence tomography (OCT) angiography. Here we report the clinical features of a patient with SLE, complicated by Kikuchi-Fujimoto disease, who developed vaso-occlusive retinopathy. We then describe the subsequent recovery of the macular capillaries as assessed by OCT angiography. CASE: A 16-year-old male was referred to us with fever, a 1-month history of violaceous red papules and erythematous plaques on his face and a painful nodule in his right neck...
July 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28687121/new-imaging-techniques-in-retinal-vasculitis
#15
REVIEW
Marina Mesquida, Víctor Llorens, Alfredo Adán
The term retinal vasculitis (RV) encompasses a heterogeneous group of sight-threatening conditions that are included in the intraocular inflammatory diseases that affect the posterior segment of the eye. Based on the nature of the inflammatory process, RV are classified into predominantly inflammatory or ischaemic (occlusive RV). The diagnosis is clinical and the aetiology can be infectious or non-infectious (immune-mediated). RV can be an isolated ocular syndrome or be associated with a systemic disease, of which they can represent the first manifestation...
July 4, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28684050/thrombophilic-and-cardiovascular-risk-factors-for-retinal-vein-occlusion
#16
Paolo Bucciarelli, Serena M Passamonti, Francesca Gianniello, Andrea Artoni, Ida Martinelli
BACKGROUND: The role of thrombophilic and cardiovascular risk factors in different manifestations of retinal vein occlusion (RVO), i.e., central or branch RVO, and at different ages is still debated. AIMS: To evaluate the association between thrombophilic and cardiovascular risk factors and the risk of RVO (overall, separately for central and branch RVO, and at different ages). METHODS: Case-control study on 313 patients with a first objectively-confirmed RVO (216 central and 97 branch RVO) and 415 healthy individuals...
July 3, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28683483/-treatment-of-retinal-vein-occlusion-is-there-still-a-role-for-vitreoretinal-surgery
#17
Nicolas Feltgen, Lutz Lothar Hansen, Hansjürgen Agostini
Surgical manoeuvres for the treatment of retinal vein occlusion peaked at the turn of the century. The first overwhelming reports could not be confirmed in prospective studies. Furthermore, the functional success was never comparable to intravitreal drug therapy, and the manoeuvres are no longer used in clinical routine. The procedures, the surgical theory and the criticism on vitrectomy, radial optic neurotomy (RON), retinal endovascular fibrinolysis (REVL) and arteriovenous dissection (AVD) will be discussed in this paper...
July 6, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28674132/exploration-into-lipid-management-and-persistent-risk-in-patients-hospitalised-for-acute-coronary-syndrome-in-japan-explore-j-protocol-for-a-prospective-observational-study
#18
Masato Nakamura, Kiyoko Uno, Atsushi Hirayama, Junya Ako, Atsushi Nohara, Hidenori Arai, Mariko Harada-Shiba
INTRODUCTION: The present study is the largest registry study ever conducted in Japan exploring the prevalence of familial hypercholesterolaemia (FH) among patients with acute coronary syndrome (ACS). Our study aims to (1) evaluate the status of lipid management and the subsequent risk of major cardiovascular events following hospitalisation of Japanese patients with ACS in real-world clinical practice; (2) determine the proportion of Japanese patients with ACS who achieve the lipid management goal and have a reduction of event risks with strict lipid management (low-density lipoprotein-cholesterol <1...
July 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28673870/fluorescence-lifetime-imaging-ophthalmoscopy
#19
REVIEW
Chantal Dysli, Sebastian Wolf, Mikhail Y Berezin, Lydia Sauer, Martin Hammer, Martin S Zinkernagel
Imaging techniques based on retinal autofluorescence have found broad applications in ophthalmology because they are extremely sensitive and noninvasive. Conventional fundus autofluorescence measures fluorescence intensity of retinal fluorophores. It mainly derives its signal from lipofuscin at the level of the retinal pigment epithelium. Fundus autofluorescence, however, can not only be characterized by the spatial distribution of the fluorescence intensity or emission spectrum, but also by a characteristic fluorescence lifetime function...
June 30, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28671896/evaluation-of-macular-ischemia-in-eyes-with-central-retinal-vein-occlusion-an-optical-coherence-tomography-angiography-study
#20
Rima Ghashut, Yuki Muraoka, Sotaro Ooto, Yuto Iida, Yuko Miwa, Kiyoshi Suzuma, Tomoaki Murakami, Shin Kadomoto, Akitaka Tsujikawa, Nagahisa Yoshimura
PURPOSE: To quantitatively assess macular perfusion status using optical coherence tomography angiography in eyes with aflibercept-treated central retinal vein occlusion and resolved macular edema and to investigate the impact of macular morphology and perfusion status on visual function. METHODS: This prospective consecutive case series included 23 patients with central retinal vein occlusion. All patients received intravitreal aflibercept injections before analysis...
June 30, 2017: Retina
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