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Retinal occlusion

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https://www.readbyqxmd.com/read/29772049/mild-bilateral-hemorrhagic-occlusive-retinal-vasculitis-following-intracameral-vancomycin-administration-in-cataract-surgery
#1
Sruthi Arepalli, Yasha S Modi, Ryan Deasy, Sunil K Srivastava
A patient underwent cataract surgery with prophylactic intracameral vancomycin (Vancocin; Pfizer, New York City, NY) in each eye, 2 weeks apart. Four weeks after, the patient presented with a mild bilateral hemorrhagic occlusive retinal vasculitis (HORV). A systemic work-up was negative for syphilis, toxoplasmosis, Bartonella, tuberculosis, and sarcoidosis. The patient was treated with oral steroids and one intravitreal steroid injection in the left eye. Ten months after presentation, the patient's vasculitis was quiescent...
May 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29768269/long-term-results-of-combination-treatment-with-single-dose-ranibizumab-plus-photodynamic-therapy-for-retinal-angiomatous-proliferation
#2
Panagiotis Malamos, Ioannis Tservakis, Menelaos Kanakis, Chrysoula Koutsiouki, Evita Kiskira, Georgios Mylonas, John Lakoumentas, Ilias Georgalas
PURPOSE: To present functional and anatomic outcomes of combination therapy with ranibizumab and photodynamic therapy (PDT) in a series of retinal angiomatous proliferation (RAP) cases. METHODS: A total of 17 eyes of 17 patients with RAP were included. Thirteen eyes were treatment naïve and 4 were already on ranibizumab monotherapy. Combined treatment with single-dose ranibizumab and PDT was performed on all treatment-naïve cases. Follow-up was performed every month for 6-38 months, using optical coherence tomography and indocyanine green angiography when necessary...
May 16, 2018: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29763939/erratum-intra-arterial-thrombolytic-therapy-is-not-a-therapeutic-option-for-filler-related-central-retinal-artery-occlusion
#3
Yi-Chun Chen, Hsiu-Mei Wu, Shih-Jen Chen, Han-Jui Lee, Jiing-Feng Lirng, Chung-Jung Lin, Feng-Chi Chang, Chao-Bao Luo, Wan-Yuo Guo
No abstract text is available yet for this article.
May 15, 2018: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/29756580/subtypes-of-antiphospholipid-antibodies-in-neurologic-accidents-an-observational-study
#4
Maryam Sahebari, Maryam Rastin, Reza Boostani, Mohsen Forughipour, Kamila Hashemzadeh, Samira HaajSadeghi
OBJECTIVE: Until now, concomitant neurological manifestations and positive antiphospholipid antibodies (APA(s)) have been investigated in different manners. The most important conflicts in this field are whether those manifestations are directly related to APA(s) or not and treatment strategies. METHOD: In this study, adopting a different manner, we selected patients with a recently defined neurological problem (according to study protocol) and positive APA without any other risk factor, to compare types, amounts, and titer of APAs...
May 14, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29754516/acute-retinal-hemorrhage-after-pipeline-embolization-device-placement-for-treatment-of-ophthalmic-segment-aneurysm-a-case-report
#5
Nimer Adeeb, Justin Moore, Christoph J Griessenauer, Raghav Gupta, Ahad A Fazelat, Christopher S Ogilvy, Ajith J Thomas
Introduction Ophthalmic segment aneurysms may present with visual symptoms due to direct compression of the optic nerve. Treatment of these aneurysms with the Pipeline embolization device (PED) often results in visual improvement. Flow diversion, however, has also been associated with occlusion of the ophthalmic artery and visual deficits in a small subset of cases. Case report A 49-year-old Caucasian female presented with subarachnoid hemorrhage due to a ruptured anterior communicating artery aneurysm. On follow-up imaging, the patient was found to have a right asymptomatic ophthalmic segment aneurysm...
January 1, 2018: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29746443/presumed-tuberculous-multifocal-retinitis-in-patients-under-treatment-with-biologic-agents
#6
Tiago E Arantes, Luiz H Lima, Gláucio L Bressanin, Cláudia D Marques, Ângela B Duarte, Cristina Muccioli
PURPOSE: To report unique retinal fundus lesions and treatment outcomes of intraocular tuberculosis in patients under anti-tumor necrosis factor treatment. METHODS: Retrospective review of two patients with laboratorial evidence of tuberculosis who had bilateral ocular signs and symptoms not attributable to other diseases. Multimodal imaging was analyzed at the time of presentation and after the treatment initiation. The study patients underwent standard treatment for tuberculosis...
May 4, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29746405/long-term-physical-stability-sterility-and-anti-vegf-bioactivity-of-repackaged-bevacizumab-in-2-ml-glass-vials
#7
Jan S Peterson, Kenneth Rockwell, Ingrid U Scott, Michael S Ip, Paul C VanVeldhuisen, Barbara A Blodi
PURPOSE: Repackaged bevacizumab in single-dose, prefilled syringes for intravitreal injection is available, but with shelf life limited from 60 days to 90 days. For the Study of COmparative Treatments for REtinal Vein Occlusion 2 (SCORE2), 2-mL sterile glass vials were used rather than prefilled syringes to provide a longer shelf life for study supplies. METHODS: Repackaged bevacizumab in glass vials was tested at release and, for 1 lot, after 1, 3, 6, and 12 months for physical stability, including concentration, purity and appearance, and for sterility and endotoxins...
May 9, 2018: Retina
https://www.readbyqxmd.com/read/29744040/recent-advances-in-understanding-and-managing-retinal-vein-occlusions
#8
REVIEW
Daniel D Esmaili, David S Boyer
Retinal vein occlusions are the second most common form of retinal vascular disease. Previously, laser treatment for branch retinal vein occlusion and intravitreal triamcinolone acetonide for central retinal vein occlusion were the standard of care. Recent studies have demonstrated that anti-vascular endothelial growth factor (anti-VEGF) agents have a superior safety and efficacy profile for the treatment of both branch and central retinal vein occlusions. The use of wide-field fluorescein angiography has also allowed better visualization of the retinal periphery...
2018: F1000Research
https://www.readbyqxmd.com/read/29743025/risk-of-incident-atrial-fibrillation-in-patients-presenting-with-retinal-artery-or-vein-occlusion-a-nationwide-cohort-study
#9
Christine Benn Christiansen, Christian Torp-Pedersen, Jonas Bjerring Olesen, Gunnar Gislason, Morten Lamberts, Nicholas Carlson, Mathias Buron, Nikolai Juul, Gregory Y H Lip
BACKGROUND: The inter-relationships of atrial fibrillation (AF) to retinal vascular occlusions (whether retinal artery occlusion (RAO) or retinal venous occlusion (RVO)) remain unclear. It is unknown if a presentation of retinal artery or venous occlusions may indicate a new onset cardiac arrhythmia. To shed light on this association, we investigated the risk of new onset AF in patients with known RAO and RVO. METHODS: Patients with retinal occlusions from 1997 to 2011 were identified through Danish nationwide registries and matched 1:5 according to sex and age...
May 10, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29739345/atypical-central-retinal-artery-occlusion-as-the-first-presentation-of-poems-syndrome-a-case-report
#10
Panitha Jindahra, Charungthai Dejthevaporn, Pimjai Niparuck, Jariya Waisayarat, Piyaphon Cheecharoen, Thanatporn Threetong, Purit Petpiroon, Tharikarn Sujirakul, Anuchit Poonyathalang, Kavin Vanikieti
BACKGROUND: POEMS syndrome is a plasma cell disorder, which clinically manifests from paraneoplastic syndrome: polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes. The most common ocular manifestation is optic disc swelling, whereas other ocular manifestations; cystoid macular edema, serous macular detachment, venous sinus thrombosis, infiltrative orbitopathy, uveitis, neovascularization of the disc, peripapillary choroidal neovascularization and optic disc drusen, had also been reported...
May 8, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29735498/diffuse-alveolar-haemorrhage-and-libman-sacks-endocarditis-a-rare-presentation-of-antiphospholipid-syndrome
#11
Brianna Bielski, Nikhil H Shah, Donevan Westerveld, Carolyn Stalvey
A 26-year-old woman with a history of idiopathic thrombocytopaenic purpura and a 1-year history of blood-streaked sputum presented after a severe episode of haemoptysis with dyspnoea. Chest imaging revealed diffuse ground glass and bronchovascular nodules. Bronchoscopy revealed bilateral diffuse alveolar haemorrhage (DAH). Sputum and bronchoalveolar lavage studies were negative for infectious aetiologies. A transthoracic echocardiogram revealed Libman-Sacks endocarditis with severe mitral regurgitation and physical examination revealed retinal artery occlusion and Osler's nodes...
May 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29719652/simultaneous-unilateral-presentation-of-three-different-ocular-manifestations-of-granulomatosis-with-polyangiitis
#12
Ali Salehi, Farzan Kianersi, Heshmatollah Ghanbari, Zahra Dastborhan, Ebrahim Gerami, Elnaz Pirmoazzen
Purpose: To report the simultaneous presentation of three ocular manifestations of granulomatosis with polyangiitis in one eye. Case Report: A 42-year-old man with a confirmed diagnosis of granulomatosis with polyangiitis was referred to the emergency room with sudden blurred vision. Eye examination showed hyperemic conjunctiva due to necrotizing scleritis in the superior nasal quadrant of the left eye, a mass in the left superior lid, as well as central retinal artery occlusion in the same eye...
April 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29719645/intravitreal-injection-of-anti-vascular-endothelial-growth-factor-agents-for-ocular-vascular-diseases-clinical-practice-guideline
#13
Homayoun Nikkhah, Saeed Karimi, Hamid Ahmadieh, Mohsen Azarmina, Majid Abrishami, Hossein Ahoor, Yousef Alizadeh, Hasan Behboudi, Narsis Daftarian, Mohammad Hossein Dehghan, Morteza Entezari, Fereydoun Farrahi, Heshmatollah Ghanbari, Khalil Ghasemi Falavarjani, Mohammad Ali Javadi, Reza Karkhaneh, Siamak Moradian, Masoud Reza Manaviat, Morsal Mehryar, Ramin Nourinia, Mohammad Mehdi Parvaresh, Alireza Ramezani, Alireza Ragati Haghi, Mohammad Riazi-Esfahani, Masoud Soheilian, Mohsen Shahsavari, Hossein-Ali Shahriari, Zhale Rajavi, Sare Safi, Armin Shirvani, Saeed Rahmani, Hamideh Sabbaghi, Mojgan Pakbin, Bahareh Kheiri, Hossein Ziaei
Purpose: To provide the clinical recommendations for the administration of intravitreal anti-vascular endothelial growth factor (VEGF) drugs especially bavacizumab for ocular vascular diseases including diabetic macular edema, neovascular age-related macular degeneration, myopic choroidal neovascularization, retinal vein occlusion and central serous chorioretinopathy. Methods: Twenty clinical questions were developed by the guideline technical committee. Relevant websites and databases were searched to find out the pertinent clinical practice guidelines to answer the questions...
April 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29717825/treatment-of-nonarteritic-acute-central-retinal-artery-occlusion
#14
Rahul A Sharma, Michael Dattilo, Nancy J Newman, Valerie Biousse
Central retinal artery occlusion (CRAO) is an event most often caused by an embolus originating in the ipsilateral carotid artery, aortic arch, or heart. CRAO may result from partial or complete occlusion of the central retinal artery (CRA), which acts as the primary blood supply to the inner neurosensory retina, and typically results in profound vision loss and permanent visual disability. No consensus has emerged regarding the optimal treatment of CRAO. All proposed treatments are of questionable efficacy and many have uncertain risk profiles...
May 2, 2018: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29716787/management-of-acute-retinal-ischemia-follow-the-guidelines
#15
REVIEW
Valérie Biousse, Fadi Nahab, Nancy J Newman
Acute retinal arterial ischemia, including vascular transient monocular vision loss (TMVL) and branch (BRAO) and central retinal arterial occlusions (CRAO), are ocular and systemic emergencies requiring immediate diagnosis and treatment. Guidelines recommend the combination of urgent brain magnetic resonance imaging with diffusion-weighted imaging, vascular imaging, and clinical assessment to identify TMVL, BRAO, and CRAO patients at highest risk for recurrent stroke, facilitating early preventive treatments to reduce the risk of subsequent stroke and cardiovascular events...
April 28, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29716074/design-of-retinal-projection-based-near-eye-display-with-contact-lens
#16
Yuhang Wu, Chao Ping Chen, Lantian Mi, Wenbo Zhang, Jingxin Zhao, Yifan Lu, Weiqian Guo, Bing Yu, Yang Li, Nizamuddin Maitlo
We propose a design of a retinal-projection-based near-eye display for achieving ultra-large field of view, vision correction, and occlusion. Our solution is highlighted by a contact lens combo, a transparent organic light-emitting diode panel, and a twisted nematic liquid crystal panel. Its design rules are set forth in detail, followed by the results and discussion regarding the field of view, angular resolution, modulation transfer function, contrast ratio, distortion, and simulated imaging.
April 30, 2018: Optics Express
https://www.readbyqxmd.com/read/29713525/efficacy-of-osthole-in-management-of-hypoperfused-retina
#17
Ran Du, Zhao-Yang Meng, Jia-Lin Wang, Yan-Ling Wang
Purpose: To determine the effect of osthole on the retina in a chronic cerebral hypoperfusion (CCH) rat model and to investigate its therapeutic activity. Methods: Seventy-two rats were randomly allocated into 6 groups. CCH was induced by permanent bilateral common carotid artery occlusion (BCCAO) in five groups. Sham surgery was performed without occlusion of the artery in the sixth group (control group). Animals were administered with saline (model group), osthole (osthole-IG group), aspirin (aspirin group), or ginaton (ginaton group); the osthole-PI group was performed with peribulbar injection of osthole...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29708803/a-5-year-follow-up-study-of-the-treatment-of-macular-edema-due-to-retinal-vein-occlusion-using-dexamethasone-intravitreal-implants
#18
Gonzaga Garay-Aramburu, Ángela Gómez-Moreno
PURPOSE: To evaluate the long-term effects of intravitreal dexamethasone implants (IDIs) in eyes with macular edema (ME) due to retinal vein occlusion (RVO). METHODS: We reviewed the records of 10 patients followed for 5 years after they received their first IDI. The main outcome measures included changes in best corrected visual acuity (BCVA), central macular thickness (CMT), and central macular volume (CMV), and the incidence of side effects. RESULTS: Ten patients were included in the study with a mean follow-up of 65...
April 30, 2018: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29705175/ischemic-retinal-vein-occlusion-characterizing-the-more-severe-spectrum-of-retinal-vein-occlusion
#19
REVIEW
Meiaad Khayat, Michael Williams, Noemi Lois
Retinal vein occlusion (RVO), including central (CRVO), branch (BRVO) and hemicentral and hemispheric RVO, is the second most common vascular cause of visual loss, surpassed only by diabetic retinopathy. The presence and extent of retinal ischemia in RVO is associated with a worse prognosis. On this basis, most previously conducted studies considered iRVO and non-iRVO as separate entities based on set thresholds of existing retinal ischemia, as determined by fundus fluorescein angiography (FFA). Other diagnostic technologies have been used specifically in the differentiation of iCRVO and non-iCRVO...
April 26, 2018: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29704860/morphological-and-genetical-changes-of-endothelial-progenitor-cells-after-in-vitro-conversion-into-photoreceptors
#20
Shi Qiang, Hiba Amer Alsaeedi, Cheng Yuhong, Hao Yang, Li Tong, Suresh Kumar, Akon Higuchi, Abdullah A Alarfaj, Rusheni Munisvaradass, Mok Pooi Ling, Pei Cheng
BACKGROUND: Retinal degeneration is a condition ensued by various ocular disorders such as artery occlusion, diabetic retinopathy, retrolental fibroplasia and retinitis pigmentosa which cause abnormal loss of photoreceptor cells and lead to eventual vision impairment. No efficient treatment has yet been found, however, the use of stem cell therapy such as bone marrow and embryonic stem cells has opened a new treatment modality for retinal degenerative diseases. The major goal of this study is to analyze the potential of endothelial progenitor cells derived from bone marrow to differentiate into retinal neural cells for regenerative medicine purposes...
April 6, 2018: Journal of Photochemistry and Photobiology. B, Biology
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