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https://www.readbyqxmd.com/read/29240965/clinical-impact-of-repolarization-changes-in-supine-versus-upright-body-position
#1
Susanne Markendorf, Thomas Felix Lüscher, Jin-Hong Gerds-Li, Felix Schönrath, Christian Marc Schmied
BACKGROUND: The impact of postural changes on various electrocardiography (ECG) charac-teristics has only been assessed in a few small studies. This large prospective trial was con-ducted to confirm or refute preliminary data and add important results with immediate impact on daily clinical practice. METHODS: ECGs in supine and upright position from 1028 patients were analyzed. Evaluation was made according to changes in T-wave vector and direction, ST-segment deviation, heart rate, QT interval and QTc interval was performed...
December 14, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/29240004/synchronizing-gait-with-cardiac-cycle-phase-alters-heart-rate-response-during-running
#2
Keren Constantini, Abigail S L Stickford, Jeffery L Bleich, Paul D Mannheimer, Benjamin D Levine, Robert F Chapman
Timing foot strike to occur in synchrony with cardiac diastole may reduce left ventricular afterload and promote coronary and skeletal muscle perfusion. PURPOSE: To assess heart rate (HR) and metabolic responses to running when foot strikes are timed to occur exclusively during 1) the systolic phase of the cardiac cycle, or 2) the diastolic phase. METHODS: Ten elite male distance runners performed a testing session on a treadmill at 4.72 m[BULLET OPERATOR]s while matching their steps to an auditory tone and wearing a chest strap that transmitted accelerometer and ECG signals...
December 12, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29234678/follow-up-measurement-of-corrected-qt-interval-in-adult-patients-before-and-after-lung-transplantation
#3
Dirk Bandorski, Reinhard Hoeltgen, Nicole Becker, Winfried Padberg, Harilaos Bogossian, Christoph Wiedenroth, Matthias Arlt, Christian Hamm, Werner Seeger, Hossein Ardeschir Ghofrani, Matthias Hecker, Henning Gall, Konstantin Mayer
Background: Prolongation of the corrected QT (QTc) interval is well known for many drugs, some of which are an integral part of the therapeutic regimen after lung transplantation (LTX). Therefore, we investigated the QTc interval after LTX in the present study. Patients and Methods: The medical records of patients after LTX were studied for demographic data, indication of LTX, medication, and baseline and follow-up ECGs. The QT interval was corrected for the patient's heart rate using the different formulae of Bazett, Fridericia, Hodges, and Framingham...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29233092/heart-rate-variability-after-radiofrequency-ablation-of-epicardial-ganglionated-plexuses-on-the-ovine-left-atrium
#4
Vilius Kviesulaitis, Aras Puodziukynas, Dainius Haroldas Pauza, Vytautas Zabiela, Tomas Kazakevicius, Raimundas Vaitkevicius, Evaldas Diržinauskas, Vytenis Semaška, Antanas Strazdas, Ruta Unikaite, Kristina Rysevaite, Neringa Pauziene, Remigijus Zaliunas
BACKGROUND: Ganglionated plexuses (GP) are terminal parts of cardiac autonomous nervous system (ANS). Radiofrequency ablation (RFA) for atrial fibrillation (AF) possibly affects GP. Changes in heart rate variability (HRV) after RFA can reflect ANS modulation. METHODS: Epicardial RFA of GP on the left atrium (LA) was performed under the general anesthesia in 15 mature Romanov sheep. HRV was used to assess the alterations in autonomic regulation of the heart. A 24 - hour ECG monitoring was performed before the ablation, 2 days after it and at each of the 12 following months...
December 12, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29230874/symmetric-dimethylarginine-in-cats-with-hypertrophic-cardiomyopathy-and-diabetes-mellitus
#5
R Langhorn, I N Kieler, J Koch, L B Christiansen, L R Jessen
BACKGROUND: Symmetric dimethylarginine (SDMA) has been increasingly used as a marker of early chronic kidney disease (CKD) in cats, but little is known about the influence of comorbidities on SDMA in this species. HYPOTHESIS: Hypertrophic cardiomyopathy (HCM) and diabetes mellitus (DM), independently of CKD, are associated with changes in serum SDMA. ANIMALS: Ninety-four cats (17 with CKD, 40 with HCM, 17 with DM, and 20 healthy controls)...
December 12, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29230843/cardiac-function-in-pediatric-patients-with-congenital-adrenal-hyperplasia-due-to-21-hydroxylase-deficiency
#6
Christiaan F Mooij, Milanthy S Pourier, Gert Weijers, Chris L de Korte, Zina Fejzic, Hedi L Claahsen van der Grinten, Livia Kapusta
BACKGROUND: Hyperandrogenism and exogenous glucocorticoid excess may cause unfavorable changes in the cardiovascular risk profile of patients with congenital adrenal hyperplasia (CAH). OBJECTIVE: To evaluate the cardiac function in pediatric patients with CAH. PATIENTS AND METHODS: 27 pediatric patients with CAH, aged 8-16 years, were evaluated by physical examination, electrocardiogram (ECG), conventional echocardiography, tissue Doppler imaging and two-dimensional (2D) myocardial strain (rate) imaging...
December 11, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29229209/randomized-double-blind-placebo-controlled-dose-escalation-study-investigation-of-the-safety-pharmacokinetics-and-antihyperalgesic-activity-of-l-4-chlorokynurenine-in-healthy-volunteers
#7
Mark Wallace, Alexander White, Kathy A Grako, Randal Lane, Allen Jo Cato, H Ralph Snodgrass
BACKGROUND AND AIMS: Neuropathic pain is a significant medical problem needing more effective treatments with fewer side effects. Overactive glutamatergic transmission via N-methyl-d-aspartate receptors (NMDARs) are known to play a role in central sensitization and neuropathic pain. Although ketamine, a NMDAR channel-blocking antagonist, is often used for neuropathic pain, its side-effect profile and abusive potential has prompted the search for a safer effective oral analgesic. A novel oral prodrug, AV-101 (l-4 chlorokynurenine), which, in the brain, is converted into one of the most potent and selective GlyB site antagonists of the NMDAR, has been demonstrated to be active in animal models of neuropathic pain...
October 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29228515/aging-and-cardiometabolic-risk-in-european-hems-pilots-an-assessment-of-occupational-old-age-limits-as-a-regulatory-risk-management-strategy
#8
Hans Bauer, Dennis Nowak, Britta Herbig
Old-age limits are imposed in some occupations in an effort to ensure public safety. In aviation, the "Age 60 Rule" limits permissible flight operations conducted by pilots aged 60 and over. Using a retrospective cohort design, we assessed this rule's validity by comparing age-related change rates of cardiometabolic incapacitation risk markers in European helicopter emergency medical service (HEMS) pilots near age 60 with those in younger pilots. Specifically, individual clinical, laboratory, and electrocardiogram (ECG)-based risk markers and an overall cardiovascular event risk score were determined from aeromedical examination records of 66 German, Austrian, Polish, and Czech HEMS pilots (average follow-up 8...
December 11, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29223306/diagnostic-accuracy-of-multi-lead-ecgs-obtained-using-a-pocket-sized-bipolar-handheld-event-recorder
#9
Ani Nigolian, Nicolas Dayal, Haïg Nigolian, Carine Stettler, Haran Burri
BACKGROUND: Handheld ECG event recorders are useful for rhythm monitoring but only record a single lead, which may limit interpretation. We sought to investigate if a multi-lead ECG may be reconstituted using this device, and aimed to evaluate diagnostic accuracy. METHODS: A commercially-available handheld bipolar ECG event recorder was used to reconstruct a 9-lead ECG (leads I, II and III, V1-6). Tracings were analyzed independently by a cardiologist and a fellow...
November 21, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29222865/multipoint-pacing-improves-peripheral-hemodynamic-response-non-invasive-assessment-using-radial-artery-tonometry
#10
Giuseppe Ciconte, Žarko Ćalović, Gabriele Vicedomini, Amarild Cuko, Luke C McSpadden, Chunlan Jiang, Kyungmoo Ryu, Igor Caporaso, Robert Stutz, Dean Winter, Massimo Saviano, Raffaele Vitale, Manuel Conti, Vincenzo Santinelli, Carlo Pappone
BACKGOUND: Multipoint left ventricular (LV) pacing (MultiPoint™ Pacing [MPP], Abbott) improves the response rate to cardiac resynchronization therapy (CRT). We evaluated the feasibility of non-invasive radial artery tonometry (RAT) to characterize arterial pressure morphology changes (pre-ejection period [PEP] and ejection duration [ED]) between conventional CRT and MPP pacing interventions. METHODS: Patients with a MPP-enabled CRT device (Quadra Assura MP™, Abbott) underwent non-invasive RAT assessment (SphygmoCor CVMS, AtCor Medical Inc...
December 9, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29214739/evaluation-of-intradialytic-hypertension-using-bioelectrical-impedance-combined-with-echocardiography-in-maintenance-hemodialysis-patients
#11
Hongqi Ren, Dehua Gong, Xu He, Fengyu Jia, Qunpeng He, Bin Xu, Zhihong Liu
Although intra-dialytic hypertension (IDH) has been noted in clinical settings for many years, its pathogenesis remains unclear. In this cross-sectional study, we analyzed IDH incidence in our center and the correlation between postdialysis volume state and IDH. One hundred thirty-one maintenance hemodialysis (MHD) patients were enrolled in our study, and bioelectrical impedance (BIA) and echocardiography (ECG) were recorded. In addition, demographic data were collected, and laboratory examinations were conducted...
December 7, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29214319/electrocardiographic-findings-in-national-basketball-association-athletes
#12
Marc P Waase, R Kannan Mutharasan, William Whang, Marco R DiTullio, John P DiFiori, Lisa Callahan, Jimmie Mancell, Dermot Phelan, Allan Schwartz, Shunichi Homma, David J Engel
Importance: While it is known that long-term intensive athletic training is associated with cardiac structural changes that can be reflected on surface electrocardiograms (ECGs), there is a paucity of sport-specific ECG data. This study seeks to clarify the applicability of existing athlete ECG interpretation criteria to elite basketball players, an athlete group shown to develop significant athletic cardiac remodeling. Objective: To generate normative ECG data for National Basketball Association (NBA) athletes and to assess the accuracy of athlete ECG interpretation criteria in this population...
December 6, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29207924/speckle-tracking-in-transcranial-ultrasound-allows-noninvasive-analysis-of-pulsation-patterns-of-the-third-ventricle
#13
Benjamin Würzer, Cristina Laza, Jörn Pons-Kühnemann, Manfred Kaps, Bernd Junge, Florian C Roessler
Cerebrospinal fluid (CSF) flow is sensitive to many cerebral disorders. We aimed to develop a noninvasive bedside method to detect physiological and pathological CSF phenomena by measuring pulsation patterns of the third ventricle. By transcranial B-mode ultrasound, electrocardiography (ECG)-gated video loops of the third ventricle were acquired. "Speckle tracking" software was used to quantify the relative change of its width. We conducted measurements of nine cardiac cycles in 11 healthy subjects in sitting and in supine position during Valsalva maneuver to investigate the influence of an increased intracranial pressure on the relative deformation of the third ventricle...
December 1, 2017: Ultrasonic Imaging
https://www.readbyqxmd.com/read/29206569/application-of-miniature-heart-rate-data-loggers-for-use-in-large-free-moving-decapod-crustaceans-method-development-and-validation
#14
Iain J McGaw, S Clay Steell, Travis E Van Leeuwen, Erika J Eliason, Steven J Cooke
Cardiovascular responses of decapod crustaceans to environmental challenges have received extensive attention. However, nearly all of these studies have been restricted to lab-based experiments; here we describe a methodology that will enable measurement of heart rate (HR) in free-moving decapods in the field. Data storage tag heart rate and temperature loggers (DST micro-HRT; Star-Oddi) were used to record electrocardiograms (ECG) and HR in large decapod crustaceans. These loggers were originally designed for use in vertebrates and must be surgically implanted in the body cavity near the heart in order to function...
January 2018: Physiological and Biochemical Zoology: PBZ
https://www.readbyqxmd.com/read/29205986/acute-pericarditis
#15
Ville Kytö, Matti Matti Niemelä
Acute pericarditis is typically associated with a viral infection. Chest pain appearing in connection with or soon after the symptoms of infection is the characteristic symptom. Diagnosis is based on the recognition of two characteristic findings (pericardial chest pain, pericardial friction rub, new ECG changes or new pericardial effusion). Medication with an anti-inflammatory analgesic for 1 to 2 weeks is the first-line treatment. A longer course of colchicine is recommended for the prevention of recurrence of the disease...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29205672/repetitive-incessant-electrical-storm-triggered-by-early-repolarization
#16
Sofia Chatzidou, Evangelos Repasos, Sotiris Plastiras, Christos Kontogiannis, Marinos Kosmopoulos, Diamantis I Tsilimigras, Ioannis Paraskevaidis, Stelios Rokas
Early repolarization syndrome (ERS) was originally considered a normal variant with benign outcome. However, recent studies have demonstrated that it can be linked to a considerable risk of life-threatening arrhythmias and sudden cardiac death. We report a case with an extraordinary, extremely malignant clinical expression of ERS refractory to all antiarrhythmic drugs including quinidine. This case demonstrates real-time changes of dynamic electrocardiogram (ECG) preceding a polymorphic ventricular tachycardia (VT)-ventricular fibrillation (VF) and possible external factors triggering arrhythmia onset...
December 5, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29205212/experimental-identification-of-a-mathematical-model-of-human-operator-working-under-mental-stress
#17
Antoni Kopyt, Krystyna Zużewicz, Paweł Bartuzi
In engineering the human is considered as one of the system elements. In most studies, his/her model remains unchanged due to the external factors. The present study shows that a relation between the mental stress and human dynamics cannot be neglected. The dynamic characteristics of the operator model change due to external stimuli, i.e., mental stress. The aim of this study was to present identification of a mathematical human model and measurement methodology of the mental stress level. To determine the level of human response to external stimuli, the electrocardiography (ECG) and electromyography (EMG) methods were applied...
2017: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29203498/perioperative-myocardial-injury-after-noncardiac-surgery-incidence-mortality-and-characterization
#18
Christian Puelacher, Giovanna Lurati Buse, Daniela Seeberger, Lorraine Sazgary, Stella Marbot, Andreas Lampart, Jaqueline Espinola, Christoph Kindler, Angelika Hammerer, Esther Seeberger, Ivo Strebel, Karin Wildi, Raphael Twerenbold, Jeanne du Fay de Lavallaz, Luzius Steiner, Lorenz Gurke, Tobias Breidthardt, Katharina Rentsch, Andreas Buser, Danielle M Gualandro, Stefan Osswald, Christian Mueller
Background -Perioperative myocardial injury (PMI) seems to be a contributor to mortality after noncardiac surgery. Because the vast majority of PMIs are asymptomatic, PMI usually is missed in the absence of systematic screening. Methods -We performed a prospective diagnostic study enrolling consecutive patients undergoing noncardiac surgery who had a planned postoperative stay of ≥24 hours and were considered at increased cardiovascular risk. All patients received a systematic screening using serial measurements of high-sensitivity cardiac troponin T in clinical routine...
December 4, 2017: Circulation
https://www.readbyqxmd.com/read/29201955/the-relationship-of-st-segment-changes-in-lead-avr-with-outcomes-after-myocardial-infarction-a-cross-sectional-study
#19
Mohammad Reza Beyranvand, Mohammad Assadpour Piranfar, Mohammadreza Mobini, Mehdi Pishgahi
Introduction: Among the 12 leads studied in electrocardiography (ECG), lead aVR can be considered as the most forgotten part of it since no attention is paid to it as the mirror image of other leads. Therefore, the present study has been designed with the aim of evaluating the prevalence of ST segment changes in lead aVR and its relationship with the outcome of these patients. Methods: In this retrospective cross sectional study medical profiles of patients who had presented to emergency department with the final diagnosis of myocardial infarction (MI) in a 4-year period were evaluated regarding changes of ST segment in lead aVR and its relationship with in-hospital mortality, the number of vessels involved, infarct location and cardiac ejection fraction...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/29198129/hemodynamic-effects-of-epinephrine-in-rats-evaluation-by-impedance-cardiography
#20
C H Turkseven, E Pekoglu, B Buyukakilli
BACKGROUND AND OBJECTIVES: This study was aimed to examine how inotropic effects of intravenously injected epinephrine change thoracic impedance measurements and to reveal the possible effects of this change on other hemodynamic parameters by using the technique of impedance cardiography. METHODS: 10 male Wistar Albino rats were divided into two equal groups: control and epinephrine. 0.2 mg/kg of epinephrine was administered to the rats in the epinephrine group via the tail vein...
2017: Bratislavské Lekárske Listy
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