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https://www.readbyqxmd.com/read/29187156/lack-of-controlled-studies-investigating-the-risk-of-postpartum-haemorrhage-in-cesarean-delivery-after-prior-use-of-oxytocin-a-scoping-review
#1
Karin Bischoff, Monika Nothacker, Cornelius Lehane, Britta Lang, Joerg Meerpohl, Christine Schmucker
BACKGROUND: Postpartum haemorrhage (PPH) is a major cause of maternal mortality and morbidity worldwide. Experimental and clinical studies indicate that prolonged oxytocin exposure in the first or second stage of labour may be associated with impaired uterine contractility and an increased risk of atonic PPH. Therefore, particularly labouring women requiring cesarean delivery constitute a subset of patients that may exhibit an unpredictable response to oxytocin. We mapped the evidence for comparative studies investigating the hypothesis whether the risk for PPH is increased in women requiring cesarean section after induction or augmentation of labour...
November 29, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29141679/intramuscular-oxytocin-versus-intravenous-oxytocin-to-prevent-postpartum-haemorrhage-at-vaginal-delivery-labor-trial-study-protocol-for-a-randomised-controlled-trial
#2
Nita Adnan, Fiona Boland, Deirdre J Murphy
BACKGROUND: Primary postpartum haemorrhage (PPH) is one of the leading causes of maternal morbidity and mortality worldwide. The most common cause of primary PPH is uterine atony. Atonic PPH rates are increasing in developed countries despite routine active management of the third stage of labour. In less-developed countries, primary PPH remains the leading cause of maternal death. Although the value of routine oxytocics in the third stage of labour has been well established, there is inconsistent practice in the choice of agent and route of administration...
November 15, 2017: Trials
https://www.readbyqxmd.com/read/29109629/peripartum-hysterectomy-in-a-tertiary-care-hospital-epidemiology-and-outcomes
#3
Bharti Sharma, Pooja Sikka, Vanita Jain, Kajal Jain, Rashmi Bagga, Vanita Suri
Background and Aims: Peripartum hysterectomy is associated with significant maternal morbidity and mortality. We reviewed all peripartum hysterectomies at our institute over a 1-year period. The aim of this study was to determine the incidence, surgery and anesthesia-related issues of peripartum hysterectomies and to compare outcomes of emergency and electively planned peripartum hysterectomies. Material and Methods: This was a retrospective analysis of records of women who underwent emergency or elective peripartum hysterectomy in a tertiary care hospital...
July 2017: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/29016591/caesarean-section-during-second-stage-of-labor-in-a-tertiary-centre
#4
Padma Gurung, Sameer Malla, Sushma Lama, Anagha Malla, Alka Singh
BACKGROUND: There is an alarming rise in caesarean section leading to increased adverse outcomes for both the mother and fetus when compared with vaginal delivery. Within this increasing caesarean section rate, there is a concerning increase in the rate of second stage caesarean section. This study highlight the feto-maternal outcome of caesarean section in second stage of labour. METHODS: This was a retrospective cohort review of all women with a singleton, cephalic fetus at term delivered by caesarean section in the second stage of labor between April 1, 2013 and March 30, 2017 at Patan Academy of Health Sciences...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28805608/the-utility-and-effectiveness-of-an-internal-iliac-artery-balloon-occlusion-catheter-in-surgery-for-large-cervical-uterine-fibroids
#5
Hiroshi Kaneda, Yasuhisa Terao, Yuko Matsuda, Kazunari Fujino, Takafumi Ujihira, Soshi Kusunoki, Miki Kimura, Akihiko Shiraishi, Ryohei Kuwatsuru, Satoru Takeda
OBJECTIVE: Surgery for uterine cervical fibroids is difficult because of restricted surgical access and risks such as intraoperative bleeding or injury to other organs. The internal iliac artery balloon occlusion catheter (IIABOC) provides effective hemostasis for placenta previa and atonic hemorrhage, and is increasingly used in surgery for uterine fibroids for controlling intraoperative hemorrhage. We investigated the efficacy and safety of the IIABOC for controlling intraoperative bleeding in total abdominal hysterectomies (TAH) and abdominal myomectomies (AM) for large cervical fibroids...
August 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28615049/a-case-of-acute-sheehan-s-syndrome-and-literature-review-a-rare-but-life-threatening-complication-of-postpartum-hemorrhage
#6
Shinya Matsuzaki, Masayuki Endo, Yutaka Ueda, Kazuya Mimura, Aiko Kakigano, Tomomi Egawa-Takata, Keiichi Kumasawa, Kiyoshi Yoshino, Tadashi Kimura
BACKGROUND: Sheehan's syndrome occurs because of severe postpartum hemorrhage causing ischemic pituitary necrosis. Sheehan's syndrome is a well-known condition that is generally diagnosed several years postpartum. However, acute Sheehan's syndrome is rare, and clinicians have little exposure to it. It can be life-threatening. There have been no reviews of acute Sheehan's syndrome and no reports of successful pregnancies after acute Sheehan's syndrome. We present such a case, and to understand this rare condition, we have reviewed and discussed the literature pertaining to it...
June 14, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28569213/is-early-intervention-using-mansoura-vv-uterine-compression-sutures-an-effective-procedure-in-the-management-of-primary-atonic-postpartum-hemorrhage-a-prospective-study
#7
Abd Elaziz A El Refaeey, Hosam Abdelfattah, Alaa Mosbah, Anas M Gamal, Emad Fayla, Waleed Refaie, Abdelhady Zaied, Rafik I Barakat, Amal K Seleem, Mohammed Maher
BACKGROUND: Postpartum hemorrhage is the leading cause of maternal death, uterine atony accounts for 75-90% of primary postpartum hemorrhage. The efficacy of the Uterine compression suture in the treatment of atonic postpartum hemorrhage is time-tested and can be said to be almost established.The aim of this study was to assess the role of the Mansoura-VV uterine compression suture as an early intervention in the management of primary atonic postpartum hemorrhage. METHODS: This prospective observational study included 108 women with primary atonic PPH over a period of 44 months...
May 31, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28502758/the-impact-of-postpartum-hemorrhage-on-hospital-length-of%C3%A2-stay-and-inpatient-mortality-a-national-inpatient-sample-based-analysis
#8
Ariela L Marshall, Urshila Durani, Adam Bartley, Clinton E Hagen, Aneel Ashrani, Carl Rose, Ronald S Go, Rajiv K Pruthi
BACKGROUND: Postpartum hemorrhage is a major cause of maternal morbidity and mortality, but the association between postpartum hemorrhage and hospital length of stay has not been rigorously investigated. OBJECTIVE: We explored the impact of postpartum hemorrhage on hospital length of stay and inpatient mortality, as these outcomes have both clinical and economic significance. STUDY DESIGN: We performed a retrospective analysis using data from the National Inpatient Sample database during the 2012 through 2013 time period...
September 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28274173/bakri-balloon-versus-condom-loaded-foley-s-catheter-for-treatment-of-atonic-postpartum-hemorrhage-secondary-to-vaginal-delivery-a-randomized-controlled-trial
#9
Atef M Darwish, Mohamed M Abdallah, Omar M Shaaban, Mohammed K Ali, Mohamed Khalaf, Ali Mohamed A Sabra
OBJECTIVE: To assess the efficacy and safety of condom-loaded Foley's catheter versus Bakri Balloon in the management of primary atonic post partum hemorrhage (PPH) secondary to vaginal delivery. STUDY DESIGN: This study was single blinded randomized controlled trial conducted at Assiut Woman's Health Hospital, Egypt in the period between October 2014 and December 2015. It Comprised 66 women with primary atonic PPH following vaginal delivery. Eligible participants were randomly assigned to Bakri balloon (group A) or condom-loaded Foley's catheter (group B)...
March 8, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28071357/effects-of-the-kir7-1-blocker-vu590-on-spontaneous-and-agonist-induced-contractions-of-human-pregnant-myometrium
#10
Denis J Crankshaw, David A Crosby, John J Morrison
KIR7.1, an inwardly rectifying K(+) channel, plays a critical role in regulating uterine excitability during pregnancy and has been suggested as a potential new target for the treatment of conditions arising from dysfunctional uterine contractility, for example, atonic postpartum hemorrhage. The aim of this study was to investigate the effects of the selective KIR7.1 blocker, VU590, on both spontaneous and agonist-stimulated contractions of human pregnant myometrium in vitro. At a concentration of 20 µmol/L, VU590 significantly increased the mean contractile force and the frequency of spontaneous contractions ( P < 0...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/27892433/efficacy-of-prophylactic-b-lynch-suture-during-lower-segment-caesarian-section-in-high-risk-patients-for-atonic-postpartum-haemorrhage
#11
M Vijayasree
Background Postpartum Haemorrhage causes significant maternal mortality and morbidity all over the world. Active management of the third stage of labour with oxytocics is come into practice. If postpartum haemorrhage is anticipated conservative surgical procedures like B-lynch suture is being applied. Objective To evaluate the effect of elective B-Lynch suture in preventing atonic postpartum haemorrhage during emergency caesarian section with high risk factors for atonicity. Method Forty antenatal women undergoing emergency caesarean section with risk factors for atony of the uterus were selected in our study...
January 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/27599602/management-of-postpartum-hemorrhage-with-intrauterine-balloon-tamponade-using-a-condom-catheter-in-an-egyptian-setting
#12
Mohamed Kandeel, Zakaria Sanad, Hamed Ellakwa, Alaa El Halaby, Mohamed Rezk, Ibrahim Saif
OBJECTIVE: To evaluate uterine balloon tamponade using a condom catheter for the management of early postpartum hemorrhage (PPH). METHODS: In a prospective observational study at Menoufia University Hospital, Shebin Elkom, Egypt, women with early PPH were enrolled between May 2011 and September 2012. Uterine balloon tamponade with a condom catheter was applied in women who were unresponsive to uterotonics and bimanual compression; patients with successful catheter placement were included in analyses...
December 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/27567670/uterine-salvage-management-for-atonic-postpartum-hemorrhage-using-modified-lynch-suture
#13
M El-Sokkary, K Wahba, Y El-Shahawy
BACKGROUND: To assess the effectiveness of the new modified technique in order to control bleeding in women presenting with atonic, flabby uterus compared to the most commonly described technique of classic B-Lynch suture. METHOD: This study included 160 women of uncontrolled atonic postpartum hemorrhage delivered by cesarean section at Ain Shams University Maternity Hospital between January 2013 and October 2015. Participants were randomly assigned following simple randomization procedures (computerized random numbers) and divided into two groups...
August 27, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27423315/in-vitro-contractile-effects-of-agents-used-in-the-clinical-management-of-postpartum-haemorrhage
#14
John J Morrison, David A Crosby, Denis J Crankshaw
Uterine atony is a major cause of postpartum haemorrhage and maternal mortality. However, the comparative pharmacology of agents used to treat this condition is poorly understood. This study evaluates, using human pregnant myometrium in vitro, a range of contractile parameters for agents used in the clinical treatment of atonic postpartum haemorrhage. The effects of oxytocin, carbetocin, ergometrine, carboprost, syntometrine and misoprostol were investigated in 146 myometrial strips from 19 donors. The potency and maximal response values were obtained, and compared, using both maximal amplitude and mean contractile force as indices of contraction...
October 15, 2016: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27328508/short-interpregnancy-interval-after-b-lynch-uterine-compression-suture-a-case-report
#15
A Nishikawa, S Matsuzaki, K Mimura, T Kanagawa, T Kimura
PURPOSE: The influence of the B-Lynch suture technique on subsequent fertility and pregnancy outcomes is not clear. In the present report, the authors describe the case of a very short interpregnancy interval following the successful placement of a B-lynch suture and discuss the associated problems. MATERIALS AND METHODS: A 33-year-old-woman underwent cesarean section after undergoing artificial induction of labor and subsequent atonic postpartum hemorrhage. Placement of a B-Lynch brace suture successfully stopped the bleeding and preserved the uterus...
2016: Clinical and Experimental Obstetrics & Gynecology
https://www.readbyqxmd.com/read/26796679/uterine-folding-hemostasis-a-simpler-and-safer-technique-for-controlling-atonic-postpartum-hemorrhage
#16
Guang-Tai Li, Guang-Rui Li, Hong-Mei Xu, Bao-Ping Wu, Xiao-Nian Wang
OBJECTIVE: To observe the efficacy and safety of a uterine folding hemostatic technique in controlling atonic postpartum hemorrhage (PPH) during cesarean delivery. METHODS: Thirty-nine women with severe postpartum bleeding from uterine inertia, which did not react to conventional initial management protocols, underwent a uterine folding hemostasis. The procedure was to fold the uterine fundus onto the anterior wall of the corpus uterus using an absorbable suture that thread tautly through the inner myometrial layer of the uterus 1-3 cm below the fundus (not entered into uterine cavity) and 1-2 cm above and below the CS incision (entered into uterine cavity 2-4 cm medal to bilateral border of the uterus)...
October 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/26171124/emergency-obstetric-hysterectomy-a-retrospective-study-from-a-teaching-hospital-in-north-india-over-eight-years
#17
Jaya Chawla, D Arora, Mohini Paul, Sangita N Ajmani
OBJECTIVES: We sought to determine the frequency, demographic characteristics, indications, and feto-maternal outcomes associated with emergency peripartum hysterectomy in an easily accessible urban center. METHODS: We conducted a retrospective, observational, and analytical study over a period of eight years, from August 2006 to July 2014. A total of 56 cases of emergency obstetric hysterectomy (EOH) were studied in the Department of Obstetrics and Gynecology, Kasturba Hospital, New Delhi...
May 2015: Oman Medical Journal
https://www.readbyqxmd.com/read/26159666/-patient-with-a-fontan-circulation-undergoing-caesarean-section-anesthesiological-management
#18
E Schneck, V Mann, C Körner, A Jost, J Thul, J B Engel, M F Müller
Adults suffering from congenital heart diseases (CHD) represent a challenge to anesthesiologists because of the diverse pathologies, complex pathophysiology and special treatment strategies. Due to improved therapeutic options for CHD, patient quality of life and life expectancy is increasing, leaving them as a growing population including pregnant patients with CHD. This article presents the main principles of the pathophysiology and anesthesiological management of pregnant patients living with a Fontan circulation based on a case report, which was complicated by an aortic coarctation and atonic uterine hemorrhage...
July 2015: Der Anaesthesist
https://www.readbyqxmd.com/read/25873974/alternate-sequential-suture-tightening-a-novel-technique-for-uncontrolled-postpartum-hemorrhage
#19
Sharda Brata Ghosh, Y M Mala
Objective. The most commonly described technique of modified B-Lynch suture may not be suitable for all the patients presenting with flabby, atonic uterus. Study Design. A retrospective analysis of twelve patients with uncontrolled postpartum haemorrhage, who underwent this procedure from March 2007 to September 2012, was conducted. In this novel technique, sutures are passed in the lower uterine segment and are tightened alternately to control uterine bleeding. Results. Average duration of the procedure was 4 minutes (range 2-7 minutes)...
2015: Obstetrics and Gynecology International
https://www.readbyqxmd.com/read/25847112/can-drug-effects-explain-the-recent-temporal-increase-in-atonic-postpartum-haemorrhage
#20
K S Joseph, Odile Sheehy, Azar Mehrabadi, Marcelo L Urquia, Jennifer A Hutcheon, Michael Kramer, Anick Bérard
BACKGROUND: Rates of postpartum haemorrhage and atonic postpartum haemorrhage have increased in several high-income countries. We carried out a study to examine if drug use in pregnancy, or drug and other interactions, explained this increase in postpartum haemorrhage. METHODS: The linked administrative and hospital databases of the Québec Pregnancy Cohort were used to define a cohort of pregnant women in Québec, Canada, from 1998 to 2009 (n = 138,704). Case-control studies on any postpartum haemorrhage and atonic postpartum haemorrhage were carried out within this population, with up to five controls randomly selected for each case after matching on index date and hospital of delivery (incidence density sampling)...
May 2015: Paediatric and Perinatal Epidemiology
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