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Charles L Raison, Jennifer M Knight, Carmine Pariante
No abstract text is available yet for this article.
June 14, 2018: Brain, Behavior, and Immunity
Amit Kumar Jaiswal, Daya Shanker, Vikrant Sudan, Amit Singh
In the present study, the 75% alcoholic fractionation of excretory-secretory (ES) antigen isolated from 200 to 300 live P. epiclitum was assessed for its diagnostic potential for the detection of caprine amphistomosis by using antibody detection enzyme immunoassay. Prior to enzyme immunoassay, 75% alcoholic fractionation of excretory-secretory (ES) antigen was subjected to SDS- PAGE and western blot analysis for the presence of immunoreactive polypeptides. SDS-PAGE analysis of ES antigen resolved a total 7 polypeptides bands of size 56, 27, 25, 22...
June 15, 2018: Veterinary Parasitology
Hao Liu, Xiang Guo, Jingcheng Han, Ray Luo, Hai-Feng Chen
Transcription factor cyclic Adenosine monophosphate response-element binding protein plays a critical role in the cyclic AMP response pathway via its intrinsically disordered kinase inducible transactivation domain (KID). KID is one of the most studied intrinsically disordered proteins (IDPs), although most previous studies focus on characterizing its disordered state structures. An interesting question that remains to be answered is how the order-disorder transition occurs at experimental conditions. Thanks to the newly developed IDP-specific force field ff14IDPSFF, the quality of conformer sampling for IDPs has been dramatically improved...
June 14, 2018: Journal of Chemical Physics
John Henderson
No abstract text is available yet for this article.
June 2018: Pediatric Pulmonology
April Killikelly
Traditional modes of communication within the scientific community, including presentation of data at conferences and in peer-reviewed publications, use technical jargon that limits public engagement. While altering word choice is an important method for increasing public engagement, the data itself may not be enough. For example, communicating the lack of evidence that vaccines cause autism did not convince many reluctant parents to vaccinate their kids (Nyhan, Reifler, Richey, Freed, Pediatrics 133:e835-e842, 2014)...
2018: Journal of Microbiology & Biology Education: JMBE
Stephen J Lepore, Bradley N Collins, Donna L Coffman, Jonathan P Winickoff, Uma S Nair, Beth Moughan, Tyra Bryant-Stephens, Daniel Taylor, David Fleece, Melissa Godfrey
BACKGROUND: Pediatricians following clinical practice guidelines for tobacco intervention (“Ask, Advise, and Refer” [AAR]) can motivate parents to reduce child tobacco smoke exposure (TSE). However, brief clinic interventions are unable to provide the more intensive, evidence-based behavioral treatments that facilitate the knowledge, skills, and confidence that parents need to both reduce child TSE and quit smoking. We hypothesized that a multilevel treatment model integrating pediatric clinic-level AAR with individual-level, telephone counseling would promote greater long-term (12-month) child TSE reduction and parent smoking cessation than clinic-level AAR alone...
June 12, 2018: International Journal of Environmental Research and Public Health
Natasha Chong Cole, Salma M Musaad, Soo-Yeun Lee, Sharon M Donovan
OBJECTIVE: Picky eating is prevalent in young children and is associated with poor dietary quality and nutrient deficiencies. Identifying predictors of picky eating could inform the development of anticipatory feeding guidance for parents and caregivers of young children. This study identified the association between factors of the home feeding environment with picky eating behavior in a cohort of preschool-aged children. METHODS: Parents of preschool-aged children (n = 497) completed questionnaires including measures of the home feeding environment (i...
June 7, 2018: Eating Behaviors
Mario Manto, Thierry A G M Huisman
The cerebellum is now at the forefront of research in neuroscience. This is not just a coincidence, occurring about 250 years after the first description of the human cerebellum. The cerebellum contains the majority of neurons in the central nervous system and it is heavily connected with almost all cortical and subcortical areas of the supratentorial region as well as with the brainstem and the spinal cord. Cerebellar circuits are embedded in large-scale networks contributing to motor control and neurocognition...
2018: Handbook of Clinical Neurology
Roberta Cimmino, Carmela M A Barone, Salvatore Claps, Ettore Varricchio, Domenico Rufrano, Mariangela Caroprese, Marzia Albenzio, Pasquale De Palo, Giuseppe Campanile, Gianluca Neglia
BACKGROUND: Diet supplementation with polyphenols is a novel strategy to improve meat quality in livestock, by preventing oxidative deterioration of lipids and protein. Polyphenols have beneficial effects on both human and animal health and can be obtained from several sources, such as olive mill wastewaters (OMWW). These are severe environmental pollutants and therefore may be recycled and utilized in other sectors. The aim of this study was to evaluate growth performance, meat characteristics, fatty acid composition, antioxidant status, different forms of myoglobin and malondialdehyde formation in kids who received a diet supplemented with polyphenols obtained from OMWW...
June 11, 2018: BMC Veterinary Research
Austin E Sanders, Lindsay M Andras, Stephanie E Iantorno, Anita Hamilton, Paul D Choi, David L Skaggs
STUDY DESIGN: Prospective study of 92 patients. OBJECTIVES: To determine if the incidence of clinically significant psychological and emotional distress in adolescent idiopathic scoliosis (AIS) patients is higher than the general population and if this correlates with deformity severity. SUMMARY OF BACKGROUND DATA: Adolescents with scoliosis may exhibit a less positive outlook on life, suffer from lower self-esteem, and have more difficulty connecting with peers; however, there is conflicting evidence whether different stages of treatment prompt different psychological problems and the long-term psychological effect of scoliosis...
July 2018: Spine Deformity
Maurizio Cutolo, Amber Vanhaecke, Barbara Ruaro, Ellen Deschepper, Claudia Ickinger, Karin Melsens, Yves Piette, Amelia Chiara Trombetta, Filip De Keyser, Vanessa Smith
OBJECTIVES: A reliable tool to evaluate flow is paramount in systemic sclerosis (SSc). We describe herein on the one hand a systematic literature review on the reliability of laser speckle contrast analysis (LASCA) to measure the peripheral blood perfusion (PBP) in SSc and perform an additional pilot study, investigating the intra- and inter-rater reliability of LASCA. METHODS: A systematic search was performed in 3 electronic databases, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines...
June 6, 2018: Autoimmunity Reviews
Véronique Bernier Gosselin, Dietrich H Volkmann, Simon Dufour, John R Middleton
The objective of this study was to predict the number of days to kidding in dairy goats by ultrasonographic measurement of three consecutive ribs and intercostal spaces or trunk diameter of fetuses. Two groups of primiparous and multiparous goats were examined by transabdominal ultrasonography. Actual kidding date was used to compute the true number of days to kidding relative to the ultrasound examination day. Linear regression models were built to predict days to kidding based on fetal measurements, parity, and number of kids...
May 30, 2018: Theriogenology
Mónica Pérez-Ríos, María I Santiago-Pérez, Alberto Malvar Pintos, Jorge Suanzes Hernández, Xurxo Hervada Vidal
OBJECTIVE: In epidemiological studies, there is no consensus on which references should be used to characterize the weight status of schoolchildren after estimating their body mass index. The aim of this study is to evaluate the influence that different criteria have on the characterization of the weight status of Galician schoolchildren from 6 to 15 years old and to identify the criterion that best characterizes central obesity. METHODS: Cross-sectional study on a sample of 7...
June 11, 2018: Revista Española de Salud Pública
(no author information available yet)
No abstract text is available yet for this article.
June 8, 2018: British Dental Journal
(no author information available yet)
On June 5, President Donald Trump signed the Childhood Cancer Survivorship, Treatment, Access and Research Act, which aims to support pediatric cancer research by expanding the collection of patient biospecimens and records, improving surveillance, and investigating pediatric survivorship.
June 7, 2018: Cancer Discovery
Allison Gates, Robin Featherstone, Kassi Shave, Shannon D Scott, Lisa Hartling
OBJECTIVES: TRanslating Emergency Knowledge for Kids (TREKK) and Cochrane Child Health collaborate to develop knowledge products on paediatric emergency medicine topics. Via a targeted social media promotion, we aimed to increase user interaction with the TREKK and Cochrane Child Health Twitter accounts and the uptake of TREKK Bottom Line Recommendations (BLRs) and Cochrane systematic reviews (SRs). DESIGN: Quantitative descriptive evaluation. SETTING: We undertook this study and collected data via the internet...
June 6, 2018: BMJ Open
Michał Czopowicz, Olga Szaluś-Jordanow, Marcin Mickiewicz, Agata Moroz, Lucjan Witkowski, Iwona Markowska-Daniel, Daria Reczyńska, Emilia Bagnicka, Jarosław Kaba
We carried out this study to determine for how long small ruminant lentivirus (SRLV)-specific antibodies can be detected by three commercial ELISA kits in goat kids after suckling infected does in field conditions. Forty-one kids born to SRLV-seropositive asymptomatic does were blood sampled prior to colostrum consumption, and then weekly for 6 months in total. The sera were screened with three commercial ELISA kits: whole-virus ELISA (wELISA), recombinant transmembrane and capsid antigen ELISA (TM/CA-ELISA), and surface antigen ELISA (SU-ELISA)...
June 6, 2018: Animal Science Journal, Nihon Chikusan Gakkaihō
Brian L Brooks, Taryn B Fay-McClymont, William S MacAllister, Marsha Vasserman, Elisabeth M S Sherman
Determining the validity of obtained data is an inherent part of a neuropsychological assessment. The purpose of this study was investigate the failure rate of the Memory Validity Profile (MVP) in a large clinical sample of children and adolescents with neurological diagnoses. Data were obtained from 261 consecutive patients (mean age = 12.0, SD = 3.9, range = 5-19) who were referred for a neuropsychological assessment in a tertiary care pediatric hospital and were administered the MVP. In this sample, 4...
June 6, 2018: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
Drazen Čular, Vladimir Ivančev, Alessandro M Zagatto, Mirjana Milić, Tea Beslija, Maha Sellami, Johnny Padulo
Cycling test such Wingate anaerobic test (WAnT) is used to measure anaerobic power (AP), but not anaerobic capacity (AC, i.e., the metabolic energy demand). However, in sports that do not involve cycling movements (Karate), the continuous jump for 30 s (vertical jumps for 30 s) has been extensively used to measure anaerobic performance in all young athletes. Limited information's are available concerning its validity and reliability especially in children. As such, the current study aimed to test validity and reliability of a continuous jumps test (the CJ30s), using WAnT as a reference...
2018: Frontiers in Physiology
Ivory H Loh, Teresa Schwendler, Angela C B Trude, Elizabeth T Anderson Steeves, Lawrence J Cheskin, Sarah Lange, Joel Gittelsohn
Social media and text messaging show promise as public health interventions, but little evaluation of implementation exists. The B'more Healthy Communities for Kids (BHCK) was a multilevel, multicomponent (wholesalers, food stores, recreation centers) childhood obesity prevention trial that included social media and text-messaging components. The BHCK was implemented in 28 low-income areas of Baltimore City, Maryland, in 2 waves. The texting intervention targeted 241 low-income African American caregivers (of 283), who received 3 texts/week reinforcing key messages, providing nutrition information, and weekly goals...
January 2018: Inquiry: a Journal of Medical Care Organization, Provision and Financing
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