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https://www.readbyqxmd.com/read/29909222/fallopian-tube-tumorigenesis-and-clinical-implications-for-ovarian-cancer-risk-reduction
#1
REVIEW
Allison A Gockley, Kevin M Elias
Ovarian cancer remains the leading cause of gynecologic cancer death among American women. Prevention is the only proven approach to reduce the incidence of the disease. Oral contraception, tubal ligation, and risk-reducing salpingo-oophorectomy (rrBSO) for high-risk groups are all established risk reduction strategies. This paradigm is changing as recent biologic studies suggest that many ovarian cancers, especially high-grade serous ovarian cancers, originate in the distal end of the fallopian tube rather than the ovarian surface epithelium...
June 11, 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29905821/corrigendum-for-endocrine-treatment-of-gender-dysphoric-gender-incongruent-persons-an-endocrine-society-clinical-practice-guideline
#2
(no author information available yet)
No abstract text is available yet for this article.
June 13, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29895022/diagnosis-and-treatment-of-metabolic-acidosis-in-patients-with-chronic-kidney-disease-position-statement-of-the-working-group-of-the-polish-society-of-nephrology
#3
Marcin Adamczak, Anna Masajtis-Zagajewska, Oktawia Mazanowska, Katarzyna Madziarska, Tomasz Stompór, Andrzej Więcek
Metabolic acidosis is commonly found in patients with chronic kidney disease (CKD), and its causes are: impaired ammonia excretion, reduced tubular bicarbonate reabsorption and insufficient renal bicarbonate production in relation to the amount of acids synthesised by the body and ingested with food. As the consequence, numerous metabolic abnormalities develop, which may lead to dysfunction of several organs. In observational studies, it has been found that CKD patients with metabolic acidosis are characterised by faster progression of kidney disease towards end stage kidney failure, and by increased mortality...
June 7, 2018: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29895010/metabolic-syndrome-in-thyroid-disease
#4
K Alexander Iwen, Rebecca Oelkrug, Hannes Kalscheuer, Georg Brabant
Cardiometabolic risk factors like abdominal obesity, hyperglycemia, low high-density lipoprotein (HDL) cholesterol, elevated triglycerides, and hypertension are defined as metabolic syndrome (MetS), which represents one of the most frequent endocrine disorders particularly in a society with increasing weight problems. As more and more evidence is accumulated that thyroid hormones affect components of the MetS, the present review aims to summarize the rapidly expanding knowledge on the pathophysiological interaction between thyroid hormone status and MetS...
2018: Frontiers of Hormone Research
https://www.readbyqxmd.com/read/29891226/evaluation-and-treatment-of-gender-dysphoria-to-prepare-for-gender-confirmation-surgery
#5
REVIEW
Miriam Hadj-Moussa, Dana A Ohl, William M Kuzon
BACKGROUND: Gender dysphoria is the experience of marked distress due to incongruence between genetically determined gender and experienced gender. Treatment of gender dysphoria should be individualized and multidisciplinary, involving a combination of psychotherapy, social gender transition, cross-sex hormone therapy, gender-affirming surgery, and/or ancillary procedures and services. The goal of all treatment modalities is to alleviate distress and affirm the patient's experienced gender identity...
June 8, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29888538/long-term-psychological-and-educational-outcomes-for-survivors-of-neuroblastoma-a-report-from-the-childhood-cancer-survivor-study
#6
Daniel J Zheng, Kevin R Krull, Yan Chen, Lisa Diller, Yutaka Yasui, Wendy Leisenring, Pim Brouwers, Rebecca Howell, Jin-Shei Lai, Lyn Balsamo, Kevin C Oeffinger, Leslie L Robison, Gregory T Armstrong, Nina S Kadan-Lottick
BACKGROUND: Neuroblastoma survivors may be at elevated risk for psychological impairments because of their young age at diagnosis and neurotoxic treatment, but this is not well described. METHODS: A total of 859 ≥5-year survivors of neuroblastoma younger than 18 years (diagnosed in 1970-1999), who had a median age at diagnosis of 0.8 years (range: 0.0-7.3 years) and a median follow-up of 13.3 years (range: 8.0-17.9 years), were compared with 872 siblings of childhood cancer survivors who were younger than 18 years with the parent-reported Behavior Problem Index (BPI) for psychological functioning...
June 11, 2018: Cancer
https://www.readbyqxmd.com/read/29863229/effects-of-long-term-combination-lt4-and-lt3-therapy-for-improving-hypothyroidism-and-overall-quality-of-life
#7
Anam Tariq, Yijin Wert, Pramil Cheriyath, Renu Joshi
OBJECTIVES: Hypothyroidism results in decreased mood and neurocognition, weight gain, fatigue, and many other undesirable symptoms. The American Association of Clinical Endocrinologists, the American Thyroid Association (ATA), and The Endocrine Society recommend levothyroxine (LT4) monotherapy as the treatment for hypothyroidism; however, after years of monotherapy, some patients continue to experience impaired quality of life. Combination LT4 and synthetic liothyronine (LT3) therapy or the use of desiccated thyroid extract (DTE), has not been suggested for this indication based on short-duration studies with no significant benefits...
June 2018: Southern Medical Journal
https://www.readbyqxmd.com/read/29857897/the-potential-role-of-endocrine-disrupting-chemicals-in-cellulite
#8
Maria Mazioti
Cellulite constitutes a major aesthetic concern affecting the majority of post-adolescent women. Current epidemiological evidence supports that the prevalence of cellulite is significantly higher in industrialized societies indicating that environmental factors have crucial role in its pathogenesis and perpetuation. Endocrine disrupting chemicals, which exist ubiquitously in the environment, are able to alter hormonal and homeostatic systems. Several of them exert agonist effects by binding to estrogen receptors and mimicking the biological activity of estrogens...
July 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29843401/consensus-in-gestational-diabetes-mellitus-looking-for-the-holy-grail
#9
REVIEW
Mukesh M Agarwal
The world's pre-eminent diabetes, obstetric, endocrine, and health organizations advocate a plethora of diverse algorithms for the screening, diagnosis, management, and follow-up of gestational diabetes mellitus (GDM). Additionally, there are regional recommendations of local health societies. Several of these proposals for GDM are contentious because some of them were developed from unscientific studies, based on expert-opinion, catered to preserve resources, and subjectively modified for convenience. Due to the wide variety of choices available, the approach to GDM can be extremely diverse even within the same hospital...
May 28, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29808075/gdm-safes-recommendations-and-action-plan-2017
#10
(no author information available yet)
The South Asian Federation of Endocrine Societies (SAFES) is an association of five national professional bodies in South Asia: The Endocrine Society of Bangladesh, Endocrine Society of India, Diabetes and Endocrine Association of Nepal, Pakistan Endocrine Society, and Endocrine Society of Sri Lanka. SAFES aim to bring together its members, to share and learn from each other, and to contribute to the growth of endocrinology in South Asia. SAFES, in consultation with each of its associations, has listed, analysed and prioritised various endocrine public health issues...
April 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29805397/lack-of-uniformity-in-screening-diagnosis-and-management-of-gestational-diabetes-mellitus-among-health-practitioners-across-major-cities-of-pakistan
#11
Syed Hunain Riaz, Muhammad Shais Khan, Ali Jawa, Madeeha Hassan, Javed Akram
Objective: To determine knowledge, attitude and practice (KAP) regarding management of Gestational Diabetes Mellitus (GDM) among Health Care Providers in major cities of Pakistan. Methods: A knowledge, attitude and practice (KAP) questionnaire based study was conducted in major cities in Pakistan from health care providers in public and private hospitals and clinics. Questionnaires were provided to the health care providers regarding screening, diagnosis and management of patients with GDM...
March 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29800559/measuring-estrogens-in-women-men-and-children-recent-advances-2012-2017
#12
Laura Smy, Joely Straseski
The measurement of estrogens is important for diagnosing and monitoring the health of women, men, and children. For example, for postmenopausal women or women undergoing treatment for breast cancer with aromatase inhibitors, the measurement of extremely low concentrations of estrogens in serum, especially estradiol, is problematic but essential for proper medical care. Achieving superb analytical sensitivity and specificity has been and continues to be a challenge for the clinical laboratory, but is a challenge that is being taken seriously...
May 22, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29789996/prevalence-and-treatment-of-central-hypogonadism-and-hypoandrogenism-in-women-with-hypopituitarism
#13
Catharina Olivius, Kerstin Landin-Wilhelmsen, Daniel S Olsson, Gudmundur Johannsson, Åsa Tivesten
PURPOSE: Women with hypopituitarism have increased morbidity and mortality, and hypogonadism has been suggested to be a contributing mechanism. The purpose of this study was to investigate the prevalence of central hypogonadism and hypoandrogenism in women with hypopituitarism at a single Swedish center. METHODS: All consecutive women (n = 184) who commenced growth hormone (GH) replacement therapy at Sahlgrenska University Hospital in Gothenburg between 1995 and 2015 were included...
May 22, 2018: Pituitary
https://www.readbyqxmd.com/read/29771759/finding-treatable-genetic-obesity-strategies-for-success
#14
Kristin Dayton, Jennifer Miller
PURPOSE OF REVIEW: Genetic obesity is responsible for up to 7% of severe childhood obesity. Although current Pediatric Endocrine Society guidelines recommend assessment of children with early-onset morbid obesity and hyperphagia for underlying genetic disorders, a vast majority of patients are not being appropriately screened for genetic obesity syndromes. RECENT FINDINGS: With advances in genetic testing, more genetic causes of obesity are being identified. Treatments are likely to be individualized, depending on the cause of the obesity, and must be targeted at addressing the underlying cause...
May 15, 2018: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29763254/gender-dysphoric-gender-incongruent-persons-treatment-recommendations-from-the-endocrine-society
#15
Jennifer Wilkes
No abstract text is available yet for this article.
May 1, 2018: American Family Physician
https://www.readbyqxmd.com/read/29741296/assessment-and-management-of-bone-health-in-women-with-oestrogen-receptor-positive-breast-cancer-receiving-endocrine-therapy-position-statement-of-the-endocrine-society-of-australia-the-australian-and-new-zealand-bone-mineral-society-the-australasian-menopause
#16
Mathis Grossmann, Sabashini Ramchand, Frances Milat, Amanda Vincent, Elgene Lim, Mark A Kotowicz, Jill Hicks, Helena Teede
OBJECTIVE: To formulate clinical consensus recommendations on bone health assessment and management of women with oestrogen receptor-positive early breast cancer receiving endocrine therapy. METHODS: Representatives appointed by relevant Australian Medical Societies used a systematic approach for adaptation of guidelines (ADAPTE) to derive an evidence-informed position statement addressing five key questions. RESULTS: Women receiving adjuvant aromatase inhibitors and the subset of premenopausal woman on tamoxifen have accelerated bone loss and increased fracture risk...
May 9, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29738396/hypovitaminosis-d-in-orthopaedic-trauma-which-guidelines-should-be-followed
#17
Brett Schiffman, Hobie Summers, Mitchell Bernstein, Frank DiSilvio, Sarah Foyil, William Lack
OBJECTIVE: To evaluate risk factors for hypovitaminosis D and determine the baseline vitamin D supplementation associated with normal vitamin D levels at presentation. DESIGN: Prospective observational study. SETTING: Level I trauma center. PATIENTS: 259 adult patients undergoing operative treatment for orthopaedic trauma (OTA 11-15, 21-23, 31-34, 41-44, 61-62, 70C, 81-82, 87) between January 1 and December 31, 2014...
May 3, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29733361/clinical-excellence-in-endocrinology
#18
Howard B A Baum
Context: Clinical endocrinology is a field driven largely by numerical parameters. To achieve outstanding patient care, however, the clinical endocrinologist must employ a range of skills which can collectively be called "clinical excellence." While there is extensive published guidance regarding appropriate medical management and outcomes for endocrine patients, there has been no consensus definition of excellence in the field, nor any recommendation as to how excellence can be achieved...
May 3, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29732746/american-european-and-chinese-practice-guidelines-or-consensuses-of-polycystic-ovary-syndrome-a-comparative-analysis
#19
Fang-Fang Wang, Jie-Xue Pan, Yan Wu, Yu-Hang Zhu, Paul J Hardiman, Fan Qu
Polycystic ovary syndrome (PCOS) is the most common metabolic and endocrine disorder in women. However, there is no agreement concerning how to diagnose and treat PCOS worldwide. Three practice guidelines or consensuses, including consensus from the European Society of Human Reproduction and Embryology (ESHRE)/the American Society for Reproductive Medicine (ASRM) in Rotterdam, diagnosis criteria and consensus in China, and clinical practice guideline from the Endocrine Society (ES) in the United States are widely recognized...
May 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29729004/italian-consensus-on-diagnosis-and-treatment-of-differentiated-thyroid-cancer-joint-statements-of-six-italian-societies
#20
F Pacini, F Basolo, R Bellantone, G Boni, M A Cannizzaro, M De Palma, C Durante, R Elisei, G Fadda, A Frasoldati, L Fugazzola, R Guglielmi, C P Lombardi, P Miccoli, E Papini, G Pellegriti, L Pezzullo, A Pontecorvi, M Salvatori, E Seregni, P Vitti
BACKGROUND: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. METHODS: Six scientific Italian societies entitled to cure thyroid cancer patients (the Italian Thyroid Association, the Medical Endocrinology Association, the Italian Society of Endocrinology, the Italian Association of Nuclear Medicine and Molecular Imaging, the Italian Society of Unified Endocrine Surgery and the Italian Society of Anatomic Pathology and Diagnostic Cytology) felt the need to develop a consensus report based on significant scientific advances occurred in the field...
May 4, 2018: Journal of Endocrinological Investigation
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