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https://www.readbyqxmd.com/read/29105286/strategies-to-manage-hepatitis-c-virus-infection-disease-burden-volume-4
#1
D S Chen, W Hamoudi, B Mustapha, J Layden, A Nersesov, T Reic, V Garcia, C Rios, L Mateva, O Njoya, S A Al-Busafi, M K Abdelmageed, M Abdulla, D Adda, O Akin, A Al Baqali, N Al Dweik, K Al Ejji, I Al Ghazzawi, S Al Kaabi, K Al Naamani, J Al Qamish, M Al Sadadi, J Al Salman, M AlBadri, H E Al-Romaihi, W Ampofo, K Antonov, C Anyaike, F Arome, A Bane, S Blach, M M Borodo, S M Brandon, B Bright, M T Butt, I Cardenas, H L Y Chan, C J Chen, P J Chen, R N Chien, W L Chuang, D Cuellar, M Derbala, A A Elbardiny, C Estes, E Farag, J Fung, I Gamkrelidze, J Genov, Z Ghandour, M Ghuloom, B Gomez, J Gunter, J Habeeb, O Hajelssedig, S M Himatt, I Hrstic, C C Hu, C F Huang, Y T Hui, R Jahis, D Jelev, A K John, K S Kaliaskarova, Y Kamel, J H Kao, J Khamis, H Khattabi, I Khoudri, A Konysbekova, I Kotzev, M S Lai, W C Lao, M H Lee, O Lesi, M Li, A Lo, C K Loo, B Lukšić, A Maaroufi, A O Malu, R Mitova, R Mohamed, M Morović, K Murphy, H Nde, E Ngige, R Njouom, D Nonković, S Obekpa, S Oguche, E E Okolo, O Omede, C Omuemu, P Ondoa, O Opare-Sem, S Owusu-Ofori, R O Phillips, Y N Prokopenko, H Razavi, D Razavi-Shearer, K Razavi-Shearer, B Redae, T Rinke de Wit, S Robbins, L R Roberts, S J Sanad, M Sharma, M Simonova, T H Su, K Sultan, S S Tan, K Tchernev, O T Y Tsang, S Tsang, C Tzeuton, S Ugoeze, B Uzochukwu, R Vi, A Vince, H U Wani, V W S Wong, A Workneh, R Yacoub, K I Yesmembetov, M Youbi, M F Yuen, J D Schmelzer
The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 17 countries in Africa, Asia, Europe, Latin America and the Middle East, and interventions for achieving the Global Health Sector Strategy on viral hepatitis targets-"WHO Targets" (65% reduction in HCV-related deaths, 90% reduction in new infections and 90% of infections diagnosed by 2030) were considered. Scaling up treatment and diagnosis rates over time would be required to achieve these targets in all but one country, even with the introduction of high SVR therapies...
October 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29105285/historical-epidemiology-of-hepatitis-c-virus-in-select-countries-volume-4
#2
A Maaroufi, A Vince, S M Himatt, R Mohamed, J Fung, O Opare-Sem, A Workneh, R Njouom, I Al Ghazzawi, M Abdulla, K S Kaliaskarova, S Owusu-Ofori, M K Abdelmageed, D Adda, O Akin, A Al Baqali, N Al Dweik, K Al Ejji, S Al Kaabi, K Al Naamani, J Al Qamish, M Al Sadadi, J Al Salman, M AlBadri, S A Al-Busafi, H E Al-Romaihi, W Ampofo, K Antonov, C Anyaike, F Arome, A Bane, S Blach, M M Borodo, S M Brandon, B Bright, M T Butt, I Cardenas, H L Y Chan, C J Chen, D S Chen, P J Chen, R N Chien, W L Chuang, D Cuellar, M Derbala, A A Elbardiny, C Estes, E Farag, I Gamkrelidze, V Garcia, J Genov, Z Ghandour, M Ghuloom, B Gomez, J Gunter, J Habeeb, O Hajelssedig, W Hamoudi, I Hrstic, C C Hu, C F Huang, Y T Hui, R Jahis, D Jelev, A K John, Y Kamel, J H Kao, J Khamis, H Khattabi, I Khoudri, A Konysbekova, I Kotzev, M S Lai, W C Lao, J Layden, M H Lee, O Lesi, M Li, A Lo, C K Loo, B Lukšić, A O Malu, L Mateva, R Mitova, M Morović, K Murphy, B Mustapha, H Nde, A Nersesov, E Ngige, O Njoya, D Nonković, S Obekpa, S Oguche, E E Okolo, O Omede, C Omuemu, P Ondoa, R O Phillips, Y N Prokopenko, H Razavi, D Razavi-Shearer, B Redae, T Reic, T Rinke de Wit, C Rios, S Robbins, L R Roberts, S J Sanad, J D Schmelzer, M Sharma, M Simonova, T H Su, K Sultan, S S Tan, K Tchernev, O T Y Tsang, S Tsang, C Tzeuton, S Ugoeze, B Uzochukwu, R Vi, H U Wani, V W S Wong, R Yacoub, K I Yesmembetov, M Youbi, M F Yuen, K Razavi-Shearer
Due to the introduction of newer, more efficacious treatment options, there is a pressing need for policy makers and public health officials to develop or adapt national hepatitis C virus (HCV) control strategies to the changing epidemiological landscape. To do so, detailed, country-specific data are needed to characterize the burden of chronic HCV infection. In this study of 17 countries, a literature review of published and unpublished data on HCV prevalence, viraemia, genotype, age and gender distribution, liver transplants and diagnosis and treatment rates was conducted, and inputs were validated by expert consensus in each country...
October 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29105283/the-present-and-future-disease-burden-of-hepatitis-c-virus-infections-with-today-s-treatment-paradigm-volume-4
#3
H L Y Chan, C J Chen, O Omede, J Al Qamish, K Al Naamani, A Bane, S S Tan, M Simonova, I Cardenas, M Derbala, O Akin, R O Phillips, M K Abdelmageed, M Abdulla, D Adda, A Al Baqali, N Al Dweik, K Al Ejji, I Al Ghazzawi, S Al Kaabi, M Al Sadadi, J Al Salman, M AlBadri, S A Al-Busafi, H E Al-Romaihi, W Ampofo, K Antonov, C Anyaike, F Arome, S Blach, M M Borodo, S M Brandon, B Bright, M T Butt, D S Chen, P J Chen, R N Chien, W L Chuang, D Cuellar, A A Elbardiny, C Estes, E Farag, J Fung, I Gamkrelidze, V Garcia, J Genov, Z Ghandour, M Ghuloom, B Gomez, J Gunter, J Habeeb, O Hajelssedig, W Hamoudi, S M Himatt, I Hrstic, C C Hu, C F Huang, Y T Hui, R Jahis, D Jelev, A K John, K S Kaliaskarova, Y Kamel, J H Kao, J Khamis, H Khattabi, I Khoudri, A Konysbekova, I Kotzev, M S Lai, W C Lao, J Layden, M H Lee, O Lesi, M Li, A Lo, C K Loo, B Lukšić, A Maaroufi, A O Malu, L Mateva, R Mitova, R Mohamed, M Morović, K Murphy, B Mustapha, A Nersesov, E Ngige, R Njouom, O Njoya, D Nonković, S Obekpa, S Oguche, E E Okolo, C Omuemu, P Ondoa, O Opare-Sem, S Owusu-Ofori, Y N Prokopenko, H Razavi, D Razavi-Shearer, K Razavi-Shearer, B Redae, T Reic, T Rinke de Wit, C Rios, S Robbins, L R Roberts, S J Sanad, J D Schmelzer, M Sharma, T H Su, K Sultan, K Tchernev, O T Y Tsang, S Tsang, C Tzeuton, S Ugoeze, B Uzochukwu, R Vi, A Vince, H U Wani, V W S Wong, A Workneh, R Yacoub, K I Yesmembetov, M Youbi, M F Yuen, H Nde
Factors influencing the morbidity and mortality associated with viremic hepatitis C virus (HCV) infection change over time and place, making it difficult to compare reported estimates. Models were developed for 17 countries (Bahrain, Bulgaria, Cameroon, Colombia, Croatia, Dominican Republic, Ethiopia, Ghana, Hong Kong, Jordan, Kazakhstan, Malaysia, Morocco, Nigeria, Qatar and Taiwan) to quantify and characterize the viremic population as well as forecast the changes in the infected population and the corresponding disease burden from 2015 to 2030...
October 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29078096/guided-ultrasonic-waves-for-determining-effective-orthotropic-material-parameters-of-continuous-fiber-reinforced-thermoplastic-plates
#4
Manuel Webersen, Sarah Johannesmann, Julia Düchting, Leander Claes, Bernd Henning
Ultrasonic methods are widely established in the NDE/NDT community, where they are mostly used for the detection of flaws and structural damage in various components. A different goal, despite the similar technological approach, is non-destructive material characterization, i.e. the determination of parameters like Young's modulus. Only few works on this topic have considered materials with high damping and strong anisotropy, such as continuous-fiber reinforced plastics, but due to the increasing demand in the industry, appropriate methods are needed...
October 6, 2017: Ultrasonics
https://www.readbyqxmd.com/read/29068431/towards-intelligent-interpretation-of-low-strain-pile-integrity-testing-results-using-machine-learning-techniques
#5
De-Mi Cui, Weizhong Yan, Xiao-Quan Wang, Lie-Min Lu
Low strain pile integrity testing (LSPIT), due to its simplicity and low cost, is one of the most popular NDE methods used in pile foundation construction. While performing LSPIT in the field is generally quite simple and quick, determining the integrity of the test piles by analyzing and interpreting the test signals (reflectograms) is still a manual process performed by experienced experts only. For foundation construction sites where the number of piles to be tested is large, it may take days before the expert can complete interpreting all of the piles and delivering the integrity assessment report...
October 25, 2017: Sensors
https://www.readbyqxmd.com/read/29030323/gender-and-the-association-between-long-term-prescription-opioid-use-and-new-onset-depression
#6
Joanne Salas, Jeffrey F Scherrer, Brian K Ahmedani, Laurel A Copeland, Kathleen K Bucholz, Mark D Sullivan, Thomas Burroughs, F David Schneider, Patrick J Lustman
Women have a higher prevalence of chronic non-cancer pain conditions and report more severe pain, yet, it is not known if the association between long term opioid analgesic use (OAU) and risk of a new depression episode (NDE) differs by gender. We analyzed patient data from the Veterans Health Administration (VHA; 2000 to 2012; n=70,997) and a large private-sector health care organization (2003 to 2012; n=22,981) to determine whether long-term OAU and risk of NDE differed by gender. Patients were free of depression and OAU for two years prior to baseline...
October 10, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29025866/declining-levels-of-functionally-specialized-synaptic-proteins-in-plasma-neuronal-exosomes-with-progression-of-alzheimer-s-disease
#7
Edward J Goetzl, Erin L Abner, Gregory A Jicha, Dimitrios Kapogiannis, Janice B Schwartz
Interactions of the presynaptic proteins, neuronal pentraxin 2 (NPTX2) and neurexin 2α (NRXN2α), with their respective postsynaptic functional partners, GluA4-containing glutamate (AMPA4) receptor and neuroligin 1 (NLGN1), enhance excitatory synaptic activity in some areas of the hippocampus and cerebral cortex. As early damage of such excitatory circuits in the brain tissues of participants with Alzheimer's disease (AD) correlates with cognitive losses, plasma neuron-derived exosome (NDE) levels of these 2 pairs of specialized synaptic proteins were quantified to assess their biomarker characteristics...
October 12, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28984823/defect-detection-and-segmentation-framework-for-remote-field-eddy-current-sensor-data
#8
Raphael Falque, Teresa Vidal-Calleja, Jaime Valls Miro
Remote-Field Eddy-Current (RFEC) technology is often used as a Non-Destructive Evaluation (NDE) method to prevent water pipe failures. By analyzing the RFEC data, it is possible to quantify the corrosion present in pipes. Quantifying the corrosion involves detecting defects and extracting their depth and shape. For large sections of pipelines, this can be extremely time-consuming if performed manually. Automated approaches are therefore well motivated. In this article, we propose an automated framework to locate and segment defects in individual pipe segments, starting from raw RFEC measurements taken over large pipelines...
October 6, 2017: Sensors
https://www.readbyqxmd.com/read/28954392/pulsed-eddy-current-sensing-for-critical-pipe-condition-assessment
#9
Nalika Ulapane, Alen Alempijevic, Teresa Vidal Calleja, Jaime Valls Miro
Pulsed Eddy Current (PEC) sensing is used for Non-Destructive Evaluation (NDE) of the structural integrity of metallic structures in the aircraft, railway, oil and gas sectors. Urban water utilities also have extensive large ferromagnetic structures in the form of critical pressure pipe systems made of grey cast iron, ductile cast iron and mild steel. The associated material properties render NDE of these pipes by means of electromagnetic sensing a necessity. In recent years PEC sensing has established itself as a state-of-the-art NDE technique in the critical water pipe sector...
September 26, 2017: Sensors
https://www.readbyqxmd.com/read/28949778/prenatal-cocaine-exposure-impacts-language-and-reading-into-late-adolescence-behavioral-and-erp-evidence
#10
Nicole Landi, Trey Avery, Michael J Crowley, Jia Wu, Linda Mayes
Extant research documents impaired language among children with prenatal cocaine exposure (PCE) relative to nondrug exposed (NDE) children, suggesting that cocaine alters development of neurobiological systems that support language. The current study examines behavioral and neural (electrophysiological) indices of language function in older adolescents. Specifically, we compare performance of PCE (N = 59) and NDE (N = 51) adolescents on a battery of cognitive and linguistic assessments that tap word reading, reading comprehension, semantic and grammatical processing, and IQ...
2017: Developmental Neuropsychology
https://www.readbyqxmd.com/read/28934616/a-model-based-bayesian-solution-for-characterization-of-complex-damage-scenarios-in-aerospace-composite-structures
#11
H Reed, Cara A C Leckey, A Dick, G Harvey, J Dobson
Ultrasonic damage detection and characterization is commonly used in nondestructive evaluation (NDE) of aerospace composite components. In recent years there has been an increased development of guided wave based methods. In real materials and structures, these dispersive waves result in complicated behavior in the presence of complex damage scenarios. Model-based characterization methods utilize accurate three dimensional finite element models (FEMs) of guided wave interaction with realistic damage scenarios to aid in defect identification and classification...
January 2018: Ultrasonics
https://www.readbyqxmd.com/read/28888152/altered-functional-connectivity-to-stressful-stimuli-in-prenatally-cocaine-exposed-adolescents
#12
Yasmin Zakiniaeiz, Sarah W Yip, Iris M Balodis, Cheryl M Lacadie, Dustin Scheinost, R Todd Constable, Linda C Mayes, Rajita Sinha, Marc N Potenza
BACKGROUND: Prenatal cocaine exposure (PCE) is linked to addiction and obesity vulnerability. Neural responses to stressful and appetitive cues in adolescents with PCE versus those without have been differentially linked to substance-use initiation. However, no prior studies have assessed cue-reactivity responses among PCE adolescents using a connectivity-based approach. METHODS: Twenty-two PCE and 22 non-prenatally drug-exposed (NDE) age-, sex-, IQ- and BMI-matched adolescents participated in individualized guided imagery with appetitive (favorite-food), stressful and neutral-relaxing cue scripts during functional magnetic resonance imaging...
November 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28773003/lamb-wave-damage-quantification-using-ga-based-ls-svm
#13
Fuqiang Sun, Ning Wang, Jingjing He, Xuefei Guan, Jinsong Yang
Lamb waves have been reported to be an efficient tool for non-destructive evaluations (NDE) for various application scenarios. However, accurate and reliable damage quantification using the Lamb wave method is still a practical challenge, due to the complex underlying mechanism of Lamb wave propagation and damage detection. This paper presents a Lamb wave damage quantification method using a least square support vector machine (LS-SVM) and a genetic algorithm (GA). Three damage sensitive features, namely, normalized amplitude, phase change, and correlation coefficient, were proposed to describe changes of Lamb wave characteristics caused by damage...
June 12, 2017: Materials
https://www.readbyqxmd.com/read/28772976/non-destructive-inspection-of-impact-damage-in-composite-aircraft-panels-by-ultrasonic-guided-waves-and-statistical-processing
#14
Margherita Capriotti, Hyungsuk E Kim, Francesco Lanza di Scalea, Hyonny Kim
This paper discusses a non-destructive evaluation (NDE) technique for the detection of damage in composite aircraft structures following high energy wide area blunt impact (HEWABI) from ground service equipment (GSE), such as heavy cargo loaders and other heavy equipment. The test structures typically include skin, co-cured stringers, and C-frames that are bolt-connected onto the skin with shear ties. The inspection exploits the waveguide geometry of these structures by utilizing ultrasonic guided waves and a line scan approach...
June 4, 2017: Materials
https://www.readbyqxmd.com/read/28772485/optimal-electrode-selection-for-electrical-resistance-tomography-in-carbon-fiber-reinforced-polymer-composites
#15
Luis Waldo Escalona Galvis, Paulina Diaz-Montiel, Satchi Venkataraman
Electrical Resistance Tomography (ERT) offers a non-destructive evaluation (NDE) technique that takes advantage of the inherent electrical properties in carbon fiber reinforced polymer (CFRP) composites for internal damage characterization. This paper investigates a method of optimum selection of sensing configurations for delamination detection in thick cross-ply laminates using ERT. Reduction in the number of sensing locations and measurements is necessary to minimize hardware and computational effort. The present work explores the use of an effective independence (EI) measure originally proposed for sensor location optimization in experimental vibration modal analysis...
February 4, 2017: Materials
https://www.readbyqxmd.com/read/28768532/estrogen-like-and-tissue-selective-effects-of-7-methoxycoumarin-from-ficus-umbellata-moraceae-an-in-vitro-and-in-vivo-study
#16
Stéphane Zingue, Thomas Michel, Chantal Beatrice Magne Nde, Amstrong Nang Njuh, Julia Cisilotto, Derek Tantoh Ndinteh, Colin Clyne, Xavier Fernandez, Tânia Beatriz Creczynski-Pasa, Dieudonné Njamen
BACKGROUND: Ficus umbellata is a medicinal plant previously shown to endow estrogenic properties. Its major component was isolated and characterized as 7-methoxycoumarin (MC). Noteworthy, coumarins and the respective active metabolite 7-hydroxycoumarin analogs have shown aromatase inhibitory activity, which is of particular interest in the treatment of estrogen-dependent cancers. The present work aimed at evaluating the estrogenic/antiestrogenic effects of MC in vitro and in vivo. METHODS: To do so, in vitro assays using E-screen and reporter gene were done...
August 2, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28715329/phased-array-imaging-of-complex-geometry-composite-components
#17
Alex J Brath, Francesco Simonetti
Progress in computational fluid dynamics and the availability of new composite materials are driving major advances in the design of aerospace engine components which now have highly complex geometries optimized to maximize system performance. However, shape complexity poses significant challenges to traditional nondestructive evaluation methods whose sensitivity and selectivity rapidly decrease as surface curvature increases. In addition, new aerospace materials typically exhibit an intricate microstructure that further complicates the inspection...
October 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28693813/intensity-and-memory-characteristics-of-near-death-experiences
#18
Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol, Vincent Didone, Martial Van Der Linden, Steven Laureys
Memories of Near-Death Experiences (NDEs) seem to be very detailed and stable over time. At present, there is still no satisfactory explanation for the NDEs' rich phenomenology. Here we compared phenomenological characteristics of NDE memories with the reported experience's intensity. We included 152 individuals with a self-reported "classical" NDE (i.e. occurring in life-threatening conditions). All participants completed a mailed questionnaire that included a measure of phenomenological characteristics of memories (the Memory Characteristics Questionnaire; MCQ) and a measure of NDE's intensity (the Greyson NDE scale)...
July 8, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28692534/blood-neuron-derived-exosomes-as-biomarkers-of-cognitive-impairment-in-hiv
#19
Bing Sun, Pranjali Dalvi, Linda Abadjian, Norina Tang, Lynn Pulliam
OBJECTIVE: To investigate proteins associated with neuronal damage in plasma neuron-derived exosomes (NDE) of HIV-infected study participants as a liquid biomarker for cognitive impairment. METHODS: Plasma NDE were isolated using precipitation and immunoadsorption with antibody to a cell surface-specific neuronal marker. Total exosomes and NDE were enumerated, characterized, and proteins extracted and targets quantified by ELISA. RESULTS: Plasma NDE from 23 HIV seropositive individuals of which 11 had mild cognitive impairment, and 12 HIV seronegative controls of which three had cognitive impairment were isolated...
September 10, 2017: AIDS
https://www.readbyqxmd.com/read/28669110/near-death-experiences-in-a-multi-religious-hospital-population-in-sri-lanka
#20
Miyuru Chandradasa, Chamara Wijesinghe, K A L A Kuruppuarachchi, Mahendra Perera
Near-death experiences (NDEs) are a wide range of experiences that occur in association with impending death. There are no published studies on NDEs in general hospital populations, and studies have been mainly conducted on critically ill patients. We assessed the prevalence of NDEs and its associations in a multi-religious population in a general hospital in Sri Lanka. A randomised sample of patients admitted to the Colombo North Teaching Hospital was assessed using the Greyson NDE scale and clinical assessment...
July 1, 2017: Journal of Religion and Health
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