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https://www.readbyqxmd.com/read/28219762/evaluation-of-the-performances-of-twelve-rapid-diagnostic-tests-for-diagnosis-of-hiv-infection-in-yaounde-cameroon
#1
Richard Njouom, Laure Ngono, Desirée Denise Mekinda-Gometi, Cyprien Kengne Ndé, Serge Alain Sadeuh-Mba, Marie-Astrid Vernet, Patrice Tchendjou, Guy Vernet
According to the WHO/UNAIDS recommendations, an acceptable HIV rapid diagnostic tests (RDTs) has to perform a sensitivity ≥ 99% and a specificity ≥ 98%. Given the constant release of new RDTs for HIV testing in the market and the high HIV genetic diversity in Cameroon, it is interesting to monitor their performances in that setting. A total of 240 HIV positive (including 219 HIV-1M, 15 HIV-1 O, 1 HIV-1N, 1 HIV-1M/O recombinant and 4 HIV-2) and 240 HIV negative plasma samples were used to evaluate twelve routinely used RDTs in Cameroon...
February 17, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28197565/electronic-spectroscopy-of-ethyl-bromide-probed-by-vuv-photoabsorption-and-quantum-chemical-calculations
#2
Aparna Shastri, Param Jeet Singh, Sunanda Krishnakumar, Asim Kumar Das, B N Raja Sekhar
The electronically excited states of ethyl bromide and its deuterated isotopologue (C2H5Br and C2D5Br) are studied using synchrotron radiation based photoabsorption spectroscopy in the wavenumber region 50 000-86 000 cm(-1). A detailed spectral analysis supported by quantum chemical calculations is presented. A complex Rydberg series structure comprising of nsa1, npa1, npe, nda1 and nde series, converging to each of the two spin-orbit split components of the first ionization potential ((2)E3/2 and (2)E1/2) is observed for both the isotopologues...
February 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28169361/electromagnetic-pulsed-thermography-for-natural-cracks-inspection
#3
Yunlai Gao, Gui Yun Tian, Ping Wang, Haitao Wang, Bin Gao, Wai Lok Woo, Kongjing Li
Emerging integrated sensing and monitoring of material degradation and cracks are increasingly required for characterizing the structural integrity and safety of infrastructure. However, most conventional nondestructive evaluation (NDE) methods are based on single modality sensing which is not adequate to evaluate structural integrity and natural cracks. This paper proposed electromagnetic pulsed thermography for fast and comprehensive defect characterization. It hybrids multiple physical phenomena i.e. magnetic flux leakage, induced eddy current and induction heating linking to physics as well as signal processing algorithms to provide abundant information of material properties and defects...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28147584/the-symmetry-and-coupling-properties-of-solutions-in-general-anisotropic-multilayer-waveguides
#4
F Hernando Quintanilla, M J S Lowe, R V Craster
Multilayered plate and shell structures play an important role in many engineering settings where, for instance, coated pipes are commonplace such as in the petrochemical, aerospace, and power generation industries. There are numerous demands, and indeed requirements, on nondestructive evaluation (NDE) to detect defects or to measure material properties using guided waves; to choose the most suitable inspection approach, it is essential to know the properties of the guided wave solutions for any given multilayered system and this requires dispersion curves computed reliably, robustly, and accurately...
January 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28109283/ethanol-extracted-cameroonian-propolis-exerts-estrogenic-effects-and-alleviates-hot-flushes-in-ovariectomized-wistar-rats
#5
Stéphane Zingue, Chantal Beatrice Magne Nde, Thomas Michel, Derek Tantoh Ndinteh, Jules Tchatchou, Moïse Adamou, Xavier Fernandez, Fernand-Nestor Tchuenguem Fohouo, Colin Clyne, Dieudonné Njamen
BACKGROUND: Since the biological properties of propolis depend to the plants that can be found in a specific region, propolis from unexplored regions attracts the attention of scientists. Ethanolic extract of Cameroonian propolis (EEP) is used to treat various ailments including gynecological problems and amenorrhea. Since there were no scientific data to support the above claims, the present study was therefore undertaken to assess estrogenic properties of Cameroonian propolis. METHODS: To achieve our goal, the ability of EEP to induce MCF-7 cells proliferation in E-screen assay as well as to activate estrogen receptors α (ERα) and β (ERβ) in cell-based reporter gene assays using human embryonic kidney cells (HEK293T) transfected with ERs was tested...
January 21, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28067605/near-death-experiences-posttraumatic-growth-and-life-satisfaction-among-burn-survivors
#6
David Royse, Karen Badger
Survivors of large burns may face positive and negative psychological after-effects from close-to-death injuries. This study is the first to examine their near-death experiences (NDEs) and posttraumatic growth (PTG) and life satisfaction afterwards. With an available sample of 92 burn survivors, half met the criteria for an NDE using an objective scale. Those who indicated religion was a source of strength and comfort had high scores on life satisfaction, PTG, and the NDE Scale. Individuals with larger burns reported greater PTG than those with smaller total body surface area burned (TBSA)...
January 9, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28035630/knowledge-of-hypertension-and-compliance-with-therapy-among-hypertensive-patients-in-the-bamenda-health-district-of-cameroon-a-cross-sectional-study
#7
Bentley Mbekwa Akoko, Peter Nde Fon, Roland Cheofor Ngu, Kathleen Blackett Ngu
INTRODUCTION: The prevalence of hypertension has continued to increase and is now a great burden for health care providers. Obtaining information on the factors affecting compliance to antihypertensive drugs is thus important. The aim of this study was to assess knowledge of hypertension and to determine factors affecting the compliance of hypertensive patients to their antihypertensive drugs. METHODS: This was a cross-sectional study involving 221 hypertensive patients in the Bamenda Health District...
December 29, 2016: Cardiology and Therapy
https://www.readbyqxmd.com/read/28033519/characteristics-of-new-depression-diagnoses-in-patients-with-and-without-prior-chronic-opioid-use
#8
Jeffrey F Scherrer, Joanne Salas, F David Schneider, Kathleen K Bucholz, Mark D Sullivan, Laurel A Copeland, Brian K Ahmedani, Thomas Burroughs, Patrick J Lustman
: Chronic use (>90 Days) of opioid analgesics significantly increases the risk of development of new depression episodes (NDE). It is unclear whether depression that develops in this manner is similar to or different from NDE in persons not exposed to opioid analgesic use (OAU). METHODS: VA patients were classified into two groups, those who did not receive an opioid and developed depression (non-OAU+NDE, n=4314) and those that had >90 days OAU and developed NDE (OAU+NDE, n=444)...
March 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28025017/automatic-numerical-spatial-association-in-synaesthesia-an-fmri-investigation
#9
Isabel Arend, Sarit Ashkenazi, Kenneth Yuen, Shiran Ofir, Avishai Henik
A horizontal mental number line (MNL) is used to describe how quantities are represented across space. In humans, the neural correlates associated with such a representation are found in different areas of the posterior parietal cortex, especially, the intraparietal sulcus (IPS). In a phenomenon known as number-space synaesthesia, individuals visualise numbers in specific spatial locations. The experience of a MNL for number-space synaesthetes is explicit, idiosyncratic, and highly stable over time. It remains an open question whether the mechanisms underlying numerical-spatial association are shared by synaesthetes and nonsynaesthetes...
December 23, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/27999252/a-visualization-method-for-corrosion-damage-on-aluminum-plates-using-an-nd-yag-pulsed-laser-scanning-system
#10
Inbok Lee, Aoqi Zhang, Changgil Lee, Seunghee Park
This paper proposes a non-contact nondestructive evaluation (NDE) technique that uses laser-induced ultrasonic waves to visualize corrosion damage in aluminum alloy plate structures. The non-contact, pulsed-laser ultrasonic measurement system generates ultrasonic waves using a galvanometer-based Q-switched Nd:YAG laser and measures the ultrasonic waves using a piezoelectric (PZT) sensor. During scanning, a wavefield can be acquired by changing the excitation location of the laser point and measuring waves using the PZT sensor...
December 16, 2016: Sensors
https://www.readbyqxmd.com/read/27937000/do-studies-evaluating-qt-qtc-interval-prolongation-with-dietary-supplements-meet-fda-standards-a-systematic-review
#11
Tinh An Nguyen, Amy Kurian, Jessica Leong, Umang M Patel, Sachin A Shah
PURPOSE: Dietary supplement use is continuously increasing, but the safety evaluation of these products remains partial. While dietary supplements have no mandate for assessing cardiovascular safety, all new drug entities (NDE) are required to undergo a thorough QT/corrected QT (QTc) assessment to determine their propensity to impact cardiac repolarization. Independent investigators and manufacturers of dietary supplements voluntarily initiate safety studies; however, the quality of these studies is controversial...
July 4, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/27844316/occurrence-and-distribution-of-taste-and-odor-compounds-in-subtropical-water-supply-reservoirs-and-their-fates-in-water-treatment-plants
#12
Xiuzhi Bai, Ting Zhang, Chaoyi Wang, Dongliang Zong, Haipu Li, Zhaoguang Yang
Taste and odor (T&O) problems in surface water supplies attract growing environmental and ecological concerns. In this study, 10 T&O compounds, 2-methylisoborneol (2-MIB), geosmin, β-ionone, 2-isopropyl-3-methoxypyrazine (IPMP), 2-isobutyl-3-methoxypyrazine (IBMP), 2,4,6-trichloroanisole (2,4,6-TCA), 2,3,6-trichloroanisole (2,3,6-TCA), 2,3,4-trichloroanisole (2,3,4-TCA), 2,4,6-tribromoanisole (2,4,6-TBA), and trans-2,cis-6-nonadienal (NDE) were investigated in 13 water supply reservoirs and 2 water treatment plants (WTPs) in S City of China...
November 14, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27800082/caesarean-delivery-in-the-limb%C3%A3-and-the-buea-regional-hospitals-cameroon-frequency-indications-and-outcomes
#13
MULTICENTER STUDY
Tanyi John Tanyi, Julius Atashili, Peter Nde Fon, Tchounzou Robert, Koki Ndombo Paul
INTRODUCTION: Neonatal outcomes can be directly and indirectly affected by caesarean delivery (CD). Data on CD rates in semi-urban and rural hospitals in resource-limited settings are scarce and yet are needed to better guide the care of women and neonates in these settings. we carried out this study to determine the frequency of CD, its indications and the frequency of the various adverse neonatal outcomes (ANO) in the Limbe Regional Hospital (LRH) and the Buea Regional Hospital (BRH), Cameroon...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27784319/estrogenic-and-cytotoxic-potentials-of-compounds-isolated-from-millettia-macrophylla-benth-fabaceae-towards-a-better-understanding-of-its-underlying-mechanisms
#14
Stéphane Zingue, Job Tchoumtchoua, Dieudonnée Mireille Ntsa, Louis Pergaud Sandjo, Julia Cisilotto, Chantal Beatrice Magne Nde, Evelyn Winter, Charline Florence Awounfack, Derek Tantoh Ndinteh, Colin Clyne, Dieudonné Njamen, Maria Halabalaki, Tânia Beatriz Creczynski-Pasa
BACKGROUND: Millettia macrophylla was previously reported to have estrogenic effects and to prevent postmenopausal osteoporosis in Wistar rats. So, the study deals with the identification of its secondary metabolites and the evaluation of their estrogenicity and cytotoxicity toward tumoural cells. Thus, 13 known compounds were obtained from successive chromatographic columns and identified by NMR data compared to those previously reported. METHODS: In vitro estrogenicity of the isolates and the phenolic fraction (PF) of M...
October 26, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27742926/nde1-and-ndel1-from-genes-to-mal-functions-parallel-but-distinct-roles-impacting-on-neurodevelopmental-disorders-and-psychiatric-illness
#15
Nicholas J Bradshaw, Mirian A F Hayashi
NDE1 (Nuclear Distribution Element 1, also known as NudE) and NDEL1 (NDE-Like 1, also known as NudEL) are the mammalian homologues of the fungus nudE gene, with important and at least partially overlapping roles for brain development. While a large number of studies describe the various properties and functions of these proteins, many do not directly compare the similarities and differences between NDE1 and NDEL1. Although sharing a high degree structural similarity and multiple common cellular roles, each protein presents several distinct features that justify their parallel but also unique functions...
October 14, 2016: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/27735876/physical-activity-level-and-sedentary-behaviors-among-public-school-children-in-dakar-senegal-measured-by-paq-c-and-accelerometer-preliminary-results
#16
Adama Diouf, Mbeugué Thiam, Nicole Idohou-Dossou, Ousmane Diongue, Ndé Mégné, Khady Diallo, Pape Malick Sembène, Salimata Wade
Background: Physical inactivity and sedentary lifestyles are major risk factors of childhood obesity. This study aimed to measure physical activity (PA) levels by accelerometer and Physical Activity Questionnaire for Older Children (PAQ-C) among Senegalese school children and the relation with Body Mass Index (BMI) and body composition. Methodology: 156 pupils 8-11 years old were randomly selected in four elementary public schools of Dakar. BMI z-score was used to categorize children according to their weight status...
October 10, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27709126/epitope-capsid-incorporation-new-effective-approach-for-vaccine-development-for-chagas-disease
#17
Qiana L Matthews, Anitra L Farrow, Girish Rachakonda, Linlin Gu, Pius Nde, Alexandre Krendelchtchikov, Siddharth Pratap, Shruti S Sakhare, Steffanie Sabbaj, Maria F Lima, Fernando Villalta
BACKGROUND: Previously we reported that a hexon-modified adenovirus (Ad) vector containing the invasive neutralizing epitope of Trypanosoma cruzi (T. cruzi) trypomastigote gp83 (Ad5-gp83) provided immunoprotection against T. cruzi infection. The purpose of this work was to design an improved vaccine for T. cruzi using a novel epitope capsid incorporation strategy. Thus, we evaluated the immunoprotection raised by co-immunization with Ad5-gp83 and an Ad vector containing an epitope (ASP-M) of the T...
October 2016: Pathogens & Immunity
https://www.readbyqxmd.com/read/27706067/amplitude-dispersion-compensation-for-damage-detection-using-ultrasonic-guided-waves
#18
Liang Zeng, Jing Lin, Liping Huang, Ming Zhao
Besides the phase and group velocities, the amplitude of guided wave mode is also frequency dependent. This amplitude dispersion also influences the performance of guided wave methods in nondestructive evaluation (NDE) and structural health monitoring (SHM). In this paper, the effects of amplitude dispersion to the spectrum and waveform of a propagating wave-packet are investigated. It is shown that the amplitude dispersion results in distortion in the spectrum of guided wave response, and thus influences the waveform of the wave-packet...
September 30, 2016: Sensors
https://www.readbyqxmd.com/read/27665297/guided-wave-scattering-by-geometrical-change-or-damage-application-to-characterization-of-fatigue-crack-and-machined-notch
#19
Nicolas Quaegebeur, Nidhal Bouslama, Maxime Bilodeau, Robin Guitel, Patrice Masson, Ahmed Maslouhi, Philippe Micheau
Validation of guided-wave based systems for Non-Destructive Evaluation (NDE) and Structural Health Monitoring (SHM) under realistic conditions or environment requires complex setups. For this purpose, numerical or theoretical approaches are useful to save time and cost associated with experiential tests. However, the interaction with realistic geometrical (rivets, thickness changes, stiffeners, extrusions) or damage features (fatigue cracks, fillet cracks, delaminations, disbonds) must be accurately captured in order to be representative...
September 14, 2016: Ultrasonics
https://www.readbyqxmd.com/read/27601437/decreased-synaptic-proteins-in-neuronal-exosomes-of-frontotemporal-dementia-and-alzheimer-s-disease
#20
Edward J Goetzl, Dimitrios Kapogiannis, Janice B Schwartz, Iryna V Lobach, Laura Goetzl, Erin L Abner, Gregory A Jicha, Anna M Karydas, Adam Boxer, Bruce L Miller
Synaptic dysfunction occurs early in senile dementias, presumably as a result of decreased levels of functional synaptic proteins as found in autopsied brains of patients with Alzheimer's disease (AD) or frontotemporal dementia (FTD). Plasma neuronal-derived exosomes (NDEs) were recovered by precipitation and immunoabsorption from 12 patients with AD, 16 with FTD, and 28 controls in a cross-sectional study, and from 9 patients with AD, 10 with FTD, and 19 controls in a longitudinal study. Six synaptic proteins in NDE extracts were quantified by ELISAs and normalized for exosome amounts...
December 2016: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
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