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https://www.readbyqxmd.com/read/28316064/depression-among-hiv-aids-patients-on-highly-active-antiretroviral-therapy-in-the-southwest-regional-hospitals-of-cameroon-a-cross-sectional-study
#1
Pleasure Atoh Ngum, Peter Nde Fon, Roland Cheofor Ngu, Vincent Siysi Verla, Henri Namme Luma
INTRODUCTION: HIV patients are now having longer life expectancies with the use of antiretroviral therapy (ART). However, the issue of mental illness has surfaced with depression being the most common in these patients, which has markedly reduced patient adherence to ART. In Cameroon, the management of HIV/AIDS does not incorporate psychiatric manifestations and depression is therefore underdiagnosed. The aim of our study was to determine the prevalence and determinants of depressive symptoms and their association with adherence to ART among HIV/AIDS patients on HAART in the Southwest Regional Hospitals of Cameroon...
March 18, 2017: Neurology and Therapy
https://www.readbyqxmd.com/read/28303355/false-memory-susceptibility-in-coma-survivors-with-and-without-a-near-death-experience
#2
Charlotte Martial, Vanessa Charland-Verville, Hedwige Dehon, Steven Laureys
It has been postulated that memories of near-death experiences (NDEs) could be (at least in part) reconstructions based on experiencers' (NDErs) previous knowledge and could be built as a result of the individual's attempt to interpret the confusing experience. From the point of view of the experiencer, NDE memories are perceived as being unrivalled memories due to its associated rich phenomenology. However, the scientific literature devoted to the cognitive functioning of NDErs in general, and their memory performance in particular, is rather limited...
March 16, 2017: Psychological Research
https://www.readbyqxmd.com/read/28292689/white-matter-crossing-fiber-microstructure-in-adolescents-prenatally-exposed-to-cocaine
#3
Kristen P Morie, Sarah W Yip, Zu Wei Zhai, Jiansong Xu, Kristen R Hamilton, Rajita Sinha, Linda C Mayes, Marc N Potenza
BACKGROUND: Prenatal cocaine exposure (PCE) is associated with risk-taking behaviors, including increased initiation of substance use in adolescence. The neurobiological underpinnings of these behaviors in adolescents with PCE are not well understood. The goal of this study was to compare diffusion-weighted imaging data between adolescents with and without PCE using crossing-fiber models, which may provide more comprehensive estimates of white-matter microstructure within regions of multiple (e...
February 28, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28277965/effects-of-an-occupational-therapy-hand-dominance-transfer-intervention-for-soldiers-with-crossed-hand-eye-dominance
#4
Michelle Luken, Kathleen E Yancosek
Crossed dominance (CD) is defined as an individual's dominant hand and dominant eye being on opposite sides of the body. CD negatively impacts an individual's ability to accurately aim and fire long-barreled guns. The authors developed and evaluated a hand dominance transfer (HDT) intervention to improve the M16 rifle shooting accuracy, efficiency, and skill transfer. Twenty-four U.S. Army soldiers with CD were taught how to handle and fire an M16 rifle using the nondominant hand. Training was conducted at a military, indoor laser-equipped weapons simulator...
January 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28270450/ssb1-and-ssb2-cooperate-to-regulate-mouse-hematopoietic-stem-and-progenitor-cells-by-resolving-replicative-stress
#5
Wei Shi, Therese Vu, Didier Boucher, Anna Biernacka, Jules Nde, Raj K Pandita, Jasmin Straube, Glen M Boyle, Fares Al-Ejeh, Purba Nag, Jessie Jeffery, Janelle L Harris, Amanda L Bain, Marta Grzelak, Magdalena Skrzypczak, Abhishek Mitra, Norbert Dojer, Nicola Crosetto, Nicole Cloonan, Olivier J Becherel, John Finnie, Jeffrey R Skaar, Carl R Walkley, Tej K Pandita, Maga Rowicka, Krzysztof Ginalski, Steven W Lane, Kum Kum Khanna
Hematopoietic stem and progenitor cells (HSPCs) are vulnerable to endogenous damage and defects in DNA repair can limit their function. The two single-stranded DNA binding proteins SSB1 and SSB2 are crucial regulators of the DNA damage response; however their overlapping roles during normal physiology are incompletely understood. We generated mice where both Ssb1 and Ssb2 were constitutively or conditionally deleted. Constitutive Ssb1/Ssb2 double knockout (DKO) caused early embryonic lethality, while conditional Ssb1/Ssb2 double knockout (cDKO) in adult mice resulted in acute lethality due to bone marrow failure and intestinal atrophy featuring stem and progenitor cell depletion, a phenotype unexpected from the previously reported single knockout models of Ssb1 or Ssb2 Mechanistically, cDKO HSPCs showed altered replication fork dynamics, massive accumulation of DNA damage, genome-wide double strand breaks (DSBs) enriched at Ssb binding regions and CpG islands, together with the accumulation of R-loops and cytosolic ssDNA...
March 7, 2017: Blood
https://www.readbyqxmd.com/read/28268180/emat-phased-array-a-feasibility-study-of-surface-crack-detection
#6
J Isla, F Cegla
Electromagnetic-acoustic transducers (EMATs) consist of a magnet and a coil. They are advantageous in some non-destructive evaluation (NDE) applications because no direct contact with the specimen is needed to send and receive ultrasonic waves. However, EMATs commonly require excitation peak powers greater than 1kW and therefore the driving electronics and the EMAT coils have to be bulky. This has hindered the development of EMAT phased arrays with characteristics similar to those of conventional piezoelectric phased arrays...
February 14, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28254563/forward-models-for-extending-the-mechanical-damage-evaluation-capability-of-resonant-ultrasound-spectroscopy
#7
B R Goodlet, C J Torbet, E J Biedermann, L M Jauriqui, J C Aldrin, T M Pollock
Finite element (FE) modeling has been coupled with resonant ultrasound spectroscopy (RUS) for nondestructive evaluation (NDE) of high temperature damage induced by mechanical loading. Forward FE models predict mode-specific changes in resonance frequencies (ΔfR), inform RUS measurements of mode-type, and identify diagnostic resonance modes sensitive to individual or multiple concurrent damage mechanisms. The magnitude of modeled ΔfR correlate very well with the magnitude of measured ΔfR from RUS, affording quantitative assessments of damage...
February 8, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28219762/evaluation-of-the-performances-of-twelve-rapid-diagnostic-tests-for-diagnosis-of-hiv-infection-in-yaounde-cameroon
#8
Richard Njouom, Laure Ngono, Desirée Denise Mekinda-Gometi, Cyprien Kengne Ndé, Serge Alain Sadeuh-Mba, Marie-Astrid Vernet, Patrice Tchendjou, Guy Vernet
According to the WHO/UNAIDS recommendations, an acceptable HIV rapid diagnostic tests (RDTs) has to perform a sensitivity≥99% and a specificity≥98%. Given the constant release of new RDTs for HIV testing in the market and the high HIV genetic diversity in Cameroon, it is interesting to monitor their performances in that setting. A total of 240 HIV positive (including 219 HIV-1 M, 15 HIV-1 O, 1 HIV-1 N, 1 HIV-1 M/O recombinant and 4 HIV-2) and 240 HIV negative plasma samples were used to evaluate twelve routinely used RDTs in Cameroon...
May 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28197565/electronic-spectroscopy-of-ethyl-bromide-probed-by-vuv-photoabsorption-and-quantum-chemical-calculations
#9
Aparna Shastri, Param Jeet Singh, Sunanda Krishnakumar, Asim Kumar Das, B N Raja Sekhar
The electronically excited states of ethyl bromide and its deuterated isotopologue (C2H5Br and C2D5Br) are studied using synchrotron radiation based photoabsorption spectroscopy in the wavenumber region 50 000-86 000 cm(-1). A detailed spectral analysis supported by quantum chemical calculations is presented. A complex Rydberg series structure comprising of nsa1, npa1, npe, nda1 and nde series, converging to each of the two spin-orbit split components of the first ionization potential ((2)E3/2 and (2)E1/2) is observed for both the isotopologues...
February 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28169361/electromagnetic-pulsed-thermography-for-natural-cracks-inspection
#10
Yunlai Gao, Gui Yun Tian, Ping Wang, Haitao Wang, Bin Gao, Wai Lok Woo, Kongjing Li
Emerging integrated sensing and monitoring of material degradation and cracks are increasingly required for characterizing the structural integrity and safety of infrastructure. However, most conventional nondestructive evaluation (NDE) methods are based on single modality sensing which is not adequate to evaluate structural integrity and natural cracks. This paper proposed electromagnetic pulsed thermography for fast and comprehensive defect characterization. It hybrids multiple physical phenomena i.e. magnetic flux leakage, induced eddy current and induction heating linking to physics as well as signal processing algorithms to provide abundant information of material properties and defects...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28147584/the-symmetry-and-coupling-properties-of-solutions-in-general-anisotropic-multilayer-waveguides
#11
F Hernando Quintanilla, M J S Lowe, R V Craster
Multilayered plate and shell structures play an important role in many engineering settings where, for instance, coated pipes are commonplace such as in the petrochemical, aerospace, and power generation industries. There are numerous demands, and indeed requirements, on nondestructive evaluation (NDE) to detect defects or to measure material properties using guided waves; to choose the most suitable inspection approach, it is essential to know the properties of the guided wave solutions for any given multilayered system and this requires dispersion curves computed reliably, robustly, and accurately...
January 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28109283/ethanol-extracted-cameroonian-propolis-exerts-estrogenic-effects-and-alleviates-hot-flushes-in-ovariectomized-wistar-rats
#12
Stéphane Zingue, Chantal Beatrice Magne Nde, Thomas Michel, Derek Tantoh Ndinteh, Jules Tchatchou, Moïse Adamou, Xavier Fernandez, Fernand-Nestor Tchuenguem Fohouo, Colin Clyne, Dieudonné Njamen
BACKGROUND: Since the biological properties of propolis depend to the plants that can be found in a specific region, propolis from unexplored regions attracts the attention of scientists. Ethanolic extract of Cameroonian propolis (EEP) is used to treat various ailments including gynecological problems and amenorrhea. Since there were no scientific data to support the above claims, the present study was therefore undertaken to assess estrogenic properties of Cameroonian propolis. METHODS: To achieve our goal, the ability of EEP to induce MCF-7 cells proliferation in E-screen assay as well as to activate estrogen receptors α (ERα) and β (ERβ) in cell-based reporter gene assays using human embryonic kidney cells (HEK293T) transfected with ERs was tested...
January 21, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28067605/near-death-experiences-posttraumatic-growth-and-life-satisfaction-among-burn-survivors
#13
David Royse, Karen Badger
Survivors of large burns may face positive and negative psychological after-effects from close-to-death injuries. This study is the first to examine their near-death experiences (NDEs) and posttraumatic growth (PTG) and life satisfaction afterwards. With an available sample of 92 burn survivors, half met the criteria for an NDE using an objective scale. Those who indicated religion was a source of strength and comfort had high scores on life satisfaction, PTG, and the NDE Scale. Individuals with larger burns reported greater PTG than those with smaller total body surface area burned (TBSA)...
January 9, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28035630/knowledge-of-hypertension-and-compliance-with-therapy-among-hypertensive-patients-in-the-bamenda-health-district-of-cameroon-a-cross-sectional-study
#14
Bentley Mbekwa Akoko, Peter Nde Fon, Roland Cheofor Ngu, Kathleen Blackett Ngu
INTRODUCTION: The prevalence of hypertension has continued to increase and is now a great burden for health care providers. Obtaining information on the factors affecting compliance to antihypertensive drugs is thus important. The aim of this study was to assess knowledge of hypertension and to determine factors affecting the compliance of hypertensive patients to their antihypertensive drugs. METHODS: This was a cross-sectional study involving 221 hypertensive patients in the Bamenda Health District...
December 29, 2016: Cardiology and Therapy
https://www.readbyqxmd.com/read/28033519/characteristics-of-new-depression-diagnoses-in-patients-with-and-without-prior-chronic-opioid-use
#15
Jeffrey F Scherrer, Joanne Salas, F David Schneider, Kathleen K Bucholz, Mark D Sullivan, Laurel A Copeland, Brian K Ahmedani, Thomas Burroughs, Patrick J Lustman
Chronic use (>90 Days) of opioid analgesics significantly increases the risk of development of new depression episodes (NDE). It is unclear whether depression that develops in this manner is similar to or different from NDE in persons not exposed to opioid analgesic use (OAU). METHODS: VA patients were classified into two groups, those who did not receive an opioid and developed depression (non-OAU+NDE, n=4314) and those that had >90 days OAU and developed NDE (OAU+NDE, n=444). OAU+NDE patients were compared to non-OAU+NDE in terms of depression severity (PHQ-9 scores), incidence of PTSD, other anxiety disorders and substance use disorders after NDE, receipt of acute phase antidepressant treatment, dual antidepressant treatment, mood stabilizers and atypical antipsychotics...
March 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28025017/automatic-numerical-spatial-association-in-synaesthesia-an-fmri-investigation
#16
Isabel Arend, Sarit Ashkenazi, Kenneth Yuen, Shiran Ofir, Avishai Henik
A horizontal mental number line (MNL) is used to describe how quantities are represented across space. In humans, the neural correlates associated with such a representation are found in different areas of the posterior parietal cortex, especially, the intraparietal sulcus (IPS). In a phenomenon known as number-space synaesthesia, individuals visualise numbers in specific spatial locations. The experience of a MNL for number-space synaesthetes is explicit, idiosyncratic, and highly stable over time. It remains an open question whether the mechanisms underlying numerical-spatial association are shared by synaesthetes and nonsynaesthetes...
December 23, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/27999252/a-visualization-method-for-corrosion-damage-on-aluminum-plates-using-an-nd-yag-pulsed-laser-scanning-system
#17
Inbok Lee, Aoqi Zhang, Changgil Lee, Seunghee Park
This paper proposes a non-contact nondestructive evaluation (NDE) technique that uses laser-induced ultrasonic waves to visualize corrosion damage in aluminum alloy plate structures. The non-contact, pulsed-laser ultrasonic measurement system generates ultrasonic waves using a galvanometer-based Q-switched Nd:YAG laser and measures the ultrasonic waves using a piezoelectric (PZT) sensor. During scanning, a wavefield can be acquired by changing the excitation location of the laser point and measuring waves using the PZT sensor...
December 16, 2016: Sensors
https://www.readbyqxmd.com/read/27937000/do-studies-evaluating-qt-qtc-interval-prolongation-with-dietary-supplements-meet-fda-standards-a-systematic-review
#18
Tinh An Nguyen, Amy Kurian, Jessica Leong, Umang M Patel, Sachin A Shah
PURPOSE: Dietary supplement use is continuously increasing, but the safety evaluation of these products remains partial. While dietary supplements have no mandate for assessing cardiovascular safety, all new drug entities (NDE) are required to undergo a thorough QT/corrected QT (QTc) assessment to determine their propensity to impact cardiac repolarization. Independent investigators and manufacturers of dietary supplements voluntarily initiate safety studies; however, the quality of these studies is controversial...
July 4, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/27844316/occurrence-and-distribution-of-taste-and-odor-compounds-in-subtropical-water-supply-reservoirs-and-their-fates-in-water-treatment-plants
#19
Xiuzhi Bai, Ting Zhang, Chaoyi Wang, Dongliang Zong, Haipu Li, Zhaoguang Yang
Taste and odor (T&O) problems in surface water supplies attract growing environmental and ecological concerns. In this study, 10 T&O compounds, 2-methylisoborneol (2-MIB), geosmin, β-ionone, 2-isopropyl-3-methoxypyrazine (IPMP), 2-isobutyl-3-methoxypyrazine (IBMP), 2,4,6-trichloroanisole (2,4,6-TCA), 2,3,6-trichloroanisole (2,3,6-TCA), 2,3,4-trichloroanisole (2,3,4-TCA), 2,4,6-tribromoanisole (2,4,6-TBA), and trans-2,cis-6-nonadienal (NDE) were investigated in 13 water supply reservoirs and 2 water treatment plants (WTPs) in S City of China...
November 14, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27800082/caesarean-delivery-in-the-limb%C3%A3-and-the-buea-regional-hospitals-cameroon-frequency-indications-and-outcomes
#20
MULTICENTER STUDY
Tanyi John Tanyi, Julius Atashili, Peter Nde Fon, Tchounzou Robert, Koki Ndombo Paul
INTRODUCTION: Neonatal outcomes can be directly and indirectly affected by caesarean delivery (CD). Data on CD rates in semi-urban and rural hospitals in resource-limited settings are scarce and yet are needed to better guide the care of women and neonates in these settings. we carried out this study to determine the frequency of CD, its indications and the frequency of the various adverse neonatal outcomes (ANO) in the Limbe Regional Hospital (LRH) and the Buea Regional Hospital (BRH), Cameroon...
2016: Pan African Medical Journal
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