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https://www.readbyqxmd.com/read/27916865/associations-of-vitamin-d-with-inter-and-intra-muscular-adipose-tissue-and-insulin-resistance-in-women-with-and-without-polycystic-ovary-syndrome
#1
David Scott, Anju Joham, Helena Teede, Melanie Gibson-Helm, Cheryce Harrison, Samantha Cassar, Samantha Hutchison, Peter R Ebeling, Nigel Stepto, Barbora de Courten
Low vitamin D and insulin resistance are common in polycystic ovary syndrome (PCOS) and associated with higher inter- and intra-muscular adipose tissue (IMAT). We investigated associations between vitamin D, IMAT and insulin resistance in a cross-sectional study of 40 women with PCOS and 30 women without PCOS, and pre- and post-exercise in a 12-week intervention in 16 overweight participants (10 with PCOS and six without PCOS). A non-classical body mass index (BMI) threshold was used to differentiate lean and overweight women (BMI ≥ 27 kg/m²)...
November 30, 2016: Nutrients
https://www.readbyqxmd.com/read/27883324/hormone-therapy-reduces-bone-resorption-but-not-bone-formation-in-postmenopausal-athletes
#2
Suzy Y Honisett, David Pagliaro, Kathy Tangalakis, Bronwyn Kingwell, Peter Ebeling, Robyn Craven, Juliana Antonopillai, Vasso Apostolopoulos, Lily Stojanovska
INTRODUCTION: Independently, hormone therapy and exercise have well-established protective effects on bone parameters. The combined effects of hormone therapy and exercise, however, are less clear. We, therefore, examined the effects of hormone therapy on bone turnover markers in postmenopausal women undergoing regular high intensity exercise. METHODS: In a randomised, double blind study, postmenopausal athletes competing at Masters level, received either hormone therapy (50 μg transdermal oestradiol, 5 mg MPA, n = 8) or placebo (n = 7) for 20 weeks...
November 1, 2016: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/27863461/pooled-genome-wide-association-detects-association-upstream-of-fcrl3-with-graves-disease
#3
Jwu Jin Khong, Kathryn P Burdon, Yi Lu, Kate Laurie, Lefta Leonardos, Paul N Baird, Srujana Sahebjada, John P Walsh, Adam Gajdatsy, Peter R Ebeling, Peter Shane Hamblin, Rosemary Wong, Simon P Forehan, Spiros Fourlanos, Anthony P Roberts, Matthew Doogue, Dinesh Selva, Grant W Montgomery, Stuart Macgregor, Jamie E Craig
BACKGROUND: Graves' disease is an autoimmune thyroid disease of complex inheritance. Multiple genetic susceptibility loci are thought to be involved in Graves' disease and it is therefore likely that these can be identified by genome wide association studies. This study aimed to determine if a genome wide association study, using a pooling methodology, could detect genomic loci associated with Graves' disease. RESULTS: Nineteen of the top ranking single nucleotide polymorphisms including HLA-DQA1 and C6orf10, were clustered within the Major Histo-compatibility Complex region on chromosome 6p21, with rs1613056 reaching genome wide significance (p = 5 × 10(-8))...
November 18, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27862146/maternal-25-hydroxyvitamin-d-is-inversely-correlated-with-fetal-serotonin
#4
Padma Murthi, Miranda Davies-Tuck, Martha Lappas, Harmeet Singh, Joanne Mockler, Rahana Rahman, Rebecca Lim, Bryan Leaw, James Doery, Euan M Wallace, Peter R Ebeling
OBJECTIVE: Maternal vitamin D deficiency during pregnancy has been linked to impaired neurocognitive development in childhood. The mechanism by which vitamin D affects childhood neurocognition is unclear but may be via interactions with serotonin, a neurotransmitter involved in fetal brain development. In this study we aimed to explore associations between maternal and fetal vitamin D concentrations, and fetal serotonin concentrations at term. STUDY DESIGN AND MEASUREMENTS: Serum 25-hydroxyitamin D (25(OH)D, nmol/L) and serotonin (5-HT, nmol/L) concentrations were measured in maternal and umbilical cord blood from mother-infant pairs (n=64)...
November 12, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27826435/bambara-wheat-composite-flour-rheological-behavior-of-dough-and-functionality-in-bread
#5
Ochuko L Erukainure, Jane N C Okafor, Akinyele Ogunji, Happiness Ukazu, Ebele N Okafor, Ijeoma L Eboagwu
The rheological behavior and functional properties of doughs from bambara-wheat composite flour was investigated. Bambara-wheat composite flour was prepared by substituting wheat with 0%, 10%, 15%, and 20% of bambara flour. The rheological behavior of their dough was analyzed with Mixolab. Breads produced from the flour were analyzed for physical characteristics. Organoleptic analysis was carried out by 20 panelists. Mixolab analysis revealed, except for stability time, depreciating values for dough consistency (C1), protein weakening (C2), starch gelatinization (C3), amylase activity (C4), and retrogradation (C5) as the inclusion of bambara flour increased...
November 2016: Food Science & Nutrition
https://www.readbyqxmd.com/read/27777981/extrapulmonary-aspergillus-infection-in-patients-with-card9-deficiency
#6
Nikolaus Rieber, Roel P Gazendam, Alexandra F Freeman, Amy P Hsu, Amanda L Collar, Janyce A Sugui, Rebecca A Drummond, Chokechai Rongkavilit, Kevin Hoffman, Carolyn Henderson, Lily Clark, Markus Mezger, Muthulekha Swamydas, Maik Engeholm, Rebecca Schüle, Bettina Neumayer, Frank Ebel, Constantinos M Mikelis, Stefania Pittaluga, Vinod K Prasad, Anurag Singh, Joshua D Milner, Kelli W Williams, Jean K Lim, Kyung J Kwon-Chung, Steven M Holland, Dominik Hartl, Taco W Kuijpers, Michail S Lionakis
Invasive pulmonary aspergillosis is a life-threatening mycosis that only affects patients with immunosuppression, chemotherapy-induced neutropenia, transplantation, or congenital immunodeficiency. We studied the clinical, genetic, histological, and immunological features of 2 unrelated patients without known immunodeficiency who developed extrapulmonary invasive aspergillosis at the ages of 8 and 18. One patient died at age 12 with progressive intra-abdominal aspergillosis. The other patient had presented with intra-abdominal candidiasis at age 9, and developed central nervous system aspergillosis at age 18 and intra-abdominal aspergillosis at age 25...
October 20, 2016: JCI Insight
https://www.readbyqxmd.com/read/27765174/implant-failure-stratos-system-for-pectus-repair
#7
Prashant K Sharma, Tineke P Willems, Daan J Touw, Willem Woudstra, Michiel E Erasmus, Tjark Ebels
BACKGROUND: Three European centers have recently reported dramatic failures of the STRATOS titanium system, approved in Europe and the United States since 2007 and meant for pectus repair, without detailed exploration of its causes. METHODS: Failed implants (fractures or loosened crimp connectors) were surgically explanted from 12 patients and biopsies taken from surrounding discolored tissue. Detailed failure analysis was performed to find the cause of failures...
October 17, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27760211/biological-role-of-paenilarvins-iturin-like-lipopeptide-secondary-metabolites-produced-by-the-honey-bee-pathogen-paenibacillus-larvae
#8
Gillian Hertlein, Marlene Seiffert, Sebastian Gensel, Eva Garcia-Gonzalez, Julia Ebeling, Ranko Skobalj, Anja Kuthning, Roderich D Süssmuth, Elke Genersch
The Gram-positive bacterium Paenibacillus larvae (P. larvae) is the causative agent of a deadly honey bee brood disease called American Foulbrood (AFB). AFB is a notifiable epizootic in most countries and, hence, P. larvae is of considerable relevance for veterinarians and apiculturists alike. Over the last decade, much progress has been made in the understanding of the (patho)biology of P. larvae. Recently, several non-ribosomally produced peptides (NRP) and peptide/polyketide (NRP/PK) hybrids produced by P...
2016: PloS One
https://www.readbyqxmd.com/read/27738633/shear-bond-strength-of-three-orthodontic-bonding-systems-on-enamel-and-restorative-materials
#9
Andreas Hellak, Jennifer Ebeling, Michael Schauseil, Steffen Stein, Matthias Roggendorf, Heike Korbmacher-Steiner
Objective. The aim of this in vitro study was to determine the shear bond strength (SBS) and adhesive remnant index (ARI) score of two self-etching no-mix adhesives (iBond™ and Scotchbond™) on different prosthetic surfaces and enamel, in comparison with the commonly used total etch system Transbond XT™. Materials and Methods. A total of 270 surfaces (1 enamel and 8 restorative surfaces, n = 30) were randomly divided into three adhesive groups. In group 1 (control) brackets were bonded with Transbond XT primer...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27738439/electrocardiographic-study-in-adult-homozygous-sickle-cell-disease-patients-in-lagos-nigeria
#10
Adedoyin Dosunmu, Akinsegun Akinbami, Ebele Uche, Adewumi Adediran, Sarah John-Olabode
Background. This study sought to identify the pattern of electrocardiographic changes in steady state adult sickle cell anaemia. Methods. A case-control, cross-sectional study was conducted amongst sickle cell patients attending the sickle cell clinic of Lagos State University Teaching Hospital, Ikeja, and HbAA controls. All consenting participants had haemoglobin electrophoresis done and were subjected to electrocardiography (ECG). The descriptive data were given as means ± standard deviation (SD). The differences were considered to be statistically significant when the p value obtained was <0...
2016: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/27721450/separating-mitochondrial-protein-assembly-and-endoplasmic-reticulum-tethering-by-selective-coupling-of-mdm10
#11
Lars Ellenrieder, Łukasz Opaliński, Lars Becker, Vivien Krüger, Oliver Mirus, Sebastian P Straub, Katharina Ebell, Nadine Flinner, Sebastian B Stiller, Bernard Guiard, Chris Meisinger, Nils Wiedemann, Enrico Schleiff, Richard Wagner, Nikolaus Pfanner, Thomas Becker
The endoplasmic reticulum-mitochondria encounter structure (ERMES) connects the mitochondrial outer membrane with the ER. Multiple functions have been linked to ERMES, including maintenance of mitochondrial morphology, protein assembly and phospholipid homeostasis. Since the mitochondrial distribution and morphology protein Mdm10 is present in both ERMES and the mitochondrial sorting and assembly machinery (SAM), it is unknown how the ERMES functions are connected on a molecular level. Here we report that conserved surface areas on opposite sides of the Mdm10 β-barrel interact with SAM and ERMES, respectively...
October 10, 2016: Nature Communications
https://www.readbyqxmd.com/read/27686459/esicm-lives-2016-part-three-milan-italy-1-5-october-2016
#12
T Velasquez, G Mackey, J Lusk, U G Kyle, T Fontenot, P Marshall, L S Shekerdemian, J A Coss-Bu, A Nishigaki, T Yatabe, T Tamura, K Yamashita, M Yokoyama, J C Ruiz-Rodriguez, B Encina, R Belmonte, I Troncoso, P Tormos, M Riveiro, J Baena, A Sanchez, J Bañeras, J Cordón, N Duran, A Ruiz, J Caballero, X Nuvials, J Riera, J Serra, A M F Rutten, S N M van Ieperen, E P H M Der Kinderen, T Van Logten, L Kovacikova, P Skrak, M Zahorec, U G Kyle, A Akcan-Arikan, J C Silva, G Mackey, J Lusk, M Goldsworthy, L S Shekerdemian, J A Coss-Bu, D Wood, D Harrison, R Parslow, P Davis, J Pappachan, S Goodwin, P Ramnarayan, S Chernyshuk, H Yemets, V Zhovnir, S M Pulitano', S De Rosa, A Mancino, G Villa, F Tosi, P Franchi, G Conti, B Patel, H Khine, A Shah, D Sung, L Singer, S Haghbin, S Inaloo, Z Serati, M Idei, T Nomura, N Yamamoto, Y Sakai, T Yoshida, Y Matsuda, Y Yamaguchi, S Takaki, O Yamaguchi, T Goto, N Longani, S Medar, I R Abdel-Aal, A S El Adawy, H M E H Mohammed, A N Mohamed, S M Parry, L D Knight, L Denehy, N De Morton, C E Baldwin, D Sani, G Kayambu, V Z M da Silva, P Phongpagdi, Z A Puthucheary, C L Granger, J E Rydingsward, C M Horkan, K B Christopher, D McWilliams, C Jones, E Reeves, G Atkins, C Snelson, L M Aitken, J Rattray, J Kenardy, A M Hull, A Ullman, R Le Brocque, M Mitchell, C Davis, B Macfarlane, J C Azevedo, L L Rocha, F F M De Freitas, A M Cavalheiro, N M Lucinio, M S Lobato, G Ebeling, A Kraegpoeth, E Laerkner, I De Brito-Ashurst, C White, S Gregory, L G Forni, E Flowers, A Curtis, C A Wood, K Siu, K Venkatesan, J B H Muhammad, L Ng, E Seet, N Baptista, A Escoval, E Tomas, R Agrawal, R Mathew, A Varma, E Dima, E Charitidou, E Perivolioti, M Pratikaki, C Vrettou, A Giannopoulos, S Zakynthinos, C Routsi, E Atchade, S Houzé, S Jean-Baptiste, G Thabut, C Genève, S Tanaka, B Lortat-Jacob, P Augustin, M Desmard, P Montravers, F J González de Molina, S Barbadillo, R Alejandro, F Álvarez-Lerma, J Vallés, R M Catalán, E Palencia, A Jareño, R M Granada, M L Ignacio, N Cui, D Liu, H Wang, L Su, H Qiu, R Li, K Jaffal, A Rouzé, J Poissy, B Sendid, S Nseir, E Paramythiotou, M Rizos, F Frantzeskaki, A Antoniadou, S Vourli, L Zerva, A Armaganidis, J Riera, J Gottlieb, M Greer, O Wiesner, M Martínez, M Acuña, J Rello, T Welte, E Atchade, T Mignot, S Houzé, S Jean-Baptiste, G Thabut, B Lortat-Jacob, S Tanaka, P Augustin, M Desmard, P Montravers, S Soussi, E Dudoignon, A Ferry, M Chaussard, M Benyamina, A Alanio, S Touratier, M Chaouat, M Lafaurie, M Mimoun, A Mebazaa, M Legrand, M A Sheils, C Patel, L Mohankumar, N Akhtar, S K Pacheco Noriega, N Navarrete Aldana, J L Ávila León, J Durand Baquero, F Fernández Bernal, E Ahmadnia, J S Hadley, M Millar, D Hall, H Hewitt, H Yasuda, M Sanui, T Komuro, S Kawano, K Andoh, H Yamamoto, E Noda, J Hatakeyama, N Saitou, H Okamoto, A Kobayashi, T Takei, S Matsukubo, H B Rotzel, A Serrano Lázaro, D Aguillón Prada, M Rodriguez Gimillo, O Diaz Barinas, M L Blasco Cortes, J Ferreres Franco, J M Segura Roca, A Carratalá, B Gonçalves, R Turon, A Mendes, F Miranda, P J Mata, D Cavalcanti, N Melo, P Lacerda, P Kurtz, C Righy, L E de la Cruz Rosario, S P Gómez Lesmes, J C García Romero, A N García Herrera, E D Díaz Pertuz, M J Gómez Sánchez, E Regidor Sanz, J Barado Hualde, A Ansotegui Hernández, J M Guergué Irazabal, V Spatenkova, O Bradac, P Suchomel, T Urli, E Heusch Lazzeri, R Aspide, M Zanello, L Perez-Borrero, J M Garcia-Alvarez, M D Arias-Verdu, E Aguilar-Alonso, R Rivera-Fernandez, J Mora-Ordoñez, C De La Fuente-Martos, E Castillo-Lorente, F Guerrero-Lopez, S P Gómez Lesmes, L E De la Cruz Rosario, E D Díaz Pertuz, A Ansotegui Hernández, J C García Romero, M J Gómez Sánchez, A N García Herrera, J Roldán Ramírez, E Regidor Sanz, J Barado Hualde, J P Tirapu León, L Navarro-Guillamón, S Cordovilla-Guardia, A Iglesias-Santiago, F Guerrero-López, E Fernández-Mondéjar, A Vidal, M Perez, A Juez, N Arias, L Colino, J L Perez, H Pérez, P Calpe, M A Alcala, D Robaglia, C Perez, S K Lan, M M Cunha, T Moreira, F Santos, E Lafuente, M J Fernandes, J G Silva, L E de la Cruz Rosario, S P Gómez Lesmes, A N García Herrera, J C García Romero, E D Díaz Pertuz, M J Gómez Sánchez, E Regidor Sanz, J G Armando Echeverría, A Ansotegui Hernández, J Barado Hualde, V Podlepich, E Sokolova, E Alexandrova, K Lapteva, P Kurtz, C Shuinotsuka, L Rabello, G Vianna, A Reis, C Cairus, J Salluh, F Bozza, J C Barrios Torres, N J Fernández Araujo, P García-Olivares, E Keough, M Dalorzo, L K Tang, I De Sousa, M Díaz, L J Marcos-Zambrano, J E Guerrero, S E Zamora Gomez, G D Hernandez Lopez, A I Vazquez Cuellar, O R Perez Nieto, J A Castanon Gonzalez, D Bhasin, S Rai, H Singh, O Gupta, M K Bhattal, S Sampley, K Sekhri, R Nandha, F A Aliaga, F Olivares, F Appiani, P Farias, F Alberto, A Hernández, S Pons, R Sonneville, L Bouadma, M Neuville, E Mariotte, A Radjou, J Lebut, S Chemam, G Voiriot, M P Dilly, B Mourvillier, R Dorent, P Nataf, M Wolff, J F Timsit, O Ediboglu, S Ataman, H Ozkarakas, C Kirakli, A Vakalos, V Avramidis, O Obukhova, I A Kurmukov, S Kashiya, E Golovnya, V N Baikova, T Ageeva, T Haritydi, E V Kulaga, J J Rios-Toro, L Perez-Borrero, E Aguilar-Alonso, M D Arias-Verdu, J M Garcia-Alvarez, C Lopez-Caler, C De La Fuente-Martos, S Rodriguez-Fernandez, M Gomez Sanchez-Orézzoli, F Martin-Gallardo, J Nikhilesh, V Joshi, E Villarreal, J Ruiz, M Gordon, A Quinza, J Gimenez, M Piñol, A Castellanos, P Ramirez, Y D Jeon, W Y Jeong, M H Kim, I Y Jeong, M Y Ahn, J Y Ahn, S H Han, J Y Choi, Y G Song, J M Kim, N S Ku, H Shah, F Kellner, F Rezai, N Mistry, P Yodice, V Ovnanian, K Fless, E Handler, R Martínez Alejos, J D Martí Romeu, D González Antón, A Quinart, A Torres Martí, M Llaurado-Serra, A Lobo-Civico, A Ventura-Rosado, A Piñol-Tena, M Pi-Guerrero, C Paños-Espinosa, M Peralvo-Bernat, J Marine-Vidal, R Gonzalez-Engroba, N Montesinos-Cerro, M Treso-Geira, A Valeiras-Valero, L Martinez-Reyes, A Sandiumenge, M F Jimenez-Herrera, S Helyar, P Riozzi, A Noon, G Hallows, H Cotton, J Keep, P A Hopkins, A Taggu, S Renuka, S Sampath, P J T Rood, T Frenzel, R Verhage, M Bonn, P Pickkers, J G van der Hoeven, M van den Boogaard, F Corradi, L Melnyk, F Moggia, R Pienovi, G Adriano, C Brusasco, L Mariotti, M Lattuada, M J Bloomer, M Coombs, K Ranse, R Endacott, B Maertens, K Blot, S Blot, M P van Nieuw Amerongen, E S van der Heiden, J W R Twisk, A R J Girbes, J J Spijkstra, P Riozzi, S Helyar, H Cotton, G Hallows, A Noon, C Bell, K Peters, A Feehan, J Keep, P A Hopkins, K Churchill, K Hawkins, R Brook, N Paver, R Endacott, N Maistry, A van Wijk, N Rouw, T van Galen, S Evelein-Brugman, A Taggu, B Krishna, S Sampath, A Putzu, M Fang, M Boscolo Berto, A Belletti, T Cassina, L Cabrini, M Mistry, Y Alhamdi, I Welters, S T Abrams, C H Toh, H S Han, E M Gil, D S Lee, C M Park, S Winder-Rhodes, R Lotay, J Doyle, M W Ke, W C Huang, C H Chiang, W T Hung, C C Cheng, K C Lin, S C Lin, K R Chiou, S R Wann, C W Shu, P L Kang, G Y Mar, C P Liu, S Dubó, A Aquevedo, M Jibaja, D Berrutti, C Labra, R Lagos, M F García, V Ramirez, M Tobar, F Picoita, C Peláez, D Carpio, L Alegría, C Hidalgo, K Godoy, J Bakker, G Hernández, Y Sadamoto, K Katabami, T Wada, Y Ono, K Maekawa, M Hayakawa, A Sawamura, S Gando, H Marin-Mateos, J L Perez-Vela, R Garcia-Gigorro, M A Corres Peiretti, M J Lopez-Gude, S Chacon-Alves, E Renes-Carreño, J C Montejo-González, K L Parlevliet, H R W Touw, M Beerepoot, C Boer, P W G Elbers, P R Tuinman, S A Abdelmonem, T A Helmy, I El Sayed, S Ghazal, S H Akhlagh, M Masjedi, K Hozhabri, E Kamali, I Zýková, B Paldusová, P Sedlák, D Morman, A M Youn, Y Ohta, M Sakuma, D Bates, T Morimoto, P L Su, W Y Chang, W C Lin, C W Chen, F Facchin, F Zarantonello, G Panciera, A De Cassai, A Venrdramin, A Ballin, T Tonetti, P Persona, C Ori, L Del Sorbo, S Rossi, G Vergani, M Cressoni, D Chiumello, C Chiurazzi, M Brioni, I Algieri, T Tonetti, M Guanziroli, A Colombo, I Tomic, A Colombo, F Crimella, E Carlesso, V Gasparovic, L Gattinoni, A Serpa Neto, M Schmidt, T Pham, A Combes, M Gama de Abreu, P Pelosi, M J Schultz, B H Katira, D Engelberts, R E Giesinger, C Ackerley, T Yoshida, D Zabini, G Otulakowski, M Post, W M Kuebler, P J McNamara, B P Kavanagh, R Pirracchio, M Resche Rigon, M Carone, S Chevret, D Annane, S Eladawy, M El-Hamamsy, N Bazan, M Elgendy, G De Pascale, M S Vallecoccia, S L Cutuli, V Di Gravio, M A Pennisi, G Conti, M Antonelli, D T Andreis, W Khaliq, M Singer, J Hartmann, S Harm, S Alcantara Carmona, P Matia Almudevar, A Naharro Abellán, J Veganzones Ramos, L Pérez Pérez, B Lobo Valbuena, N Martínez Sanz, I Fernández Simón, M Arrigo, E Feliot, N Deye, A Cariou, B Guidet, S Jaber, M Leone, M Resche-Rigon, A Vieillard Baron, M Legrand, E Gayat, A Mebazaa, M Balik, I Kolnikova, M Maly, P Waldauf, G Tavazzi, J Kristof, A Herpain, F Su, E Post, F Taccone, J L Vincent, J Creteur, C Lee, F Hatib, Z Jian, S Buddi, M Cannesson, S Fileković, M Turel, R Knafelj, V Gorjup, R Stanić, P Gradišek, O Cerović, T Mirković, M Noč, J Tirkkonen, H Hellevuo, K T Olkkola, S Hoppu, K C Lin, W T Hung, C C Chiang, W C Huang, W C Juan, S C Lin, C C Cheng, P H Lin, K Y Fong, D S Hou, P L Kang, S R Wann, Y S Chen, G Y Mar, C P Liu, M Paul, W Bougouin, G Geri, F Dumas, B Champigneulle, S Legriel, J Charpentier, J P Mira, C Sandroni, A Cariou, J Zimmerman, E Sullivan, M Noursadeghi, B Fox, D Sampson, L McHugh, T Yager, S Cermelli, T Seldon, S Bhide, R A Brandon, R B Brandon, J Zwaag, R Beunders, P Pickkers, M Kox, F Gul, M K Arslantas, D Genc, N Zibandah, L Topcu, T Akkoc, I Cinel, E Greco, M P Lauretta, D T Andreis, M Singer, I Palacios Garcia, M Cordero, A Diaz Martin, T Aldabó Pallás, J Garnacho Montero, J Revuelto Rey, L Roman Malo, A A Tanaka Montoya, A D C Amador Martinez, L Y Delgado Ayala, E Monares Zepeda, J Franco Granillo, J Aguirre Sanchez, G Camarena Alejo, A Rugerio Cabrera, A Pedraza Montenegro, T Pham, G Beduneau, F Schortgen, L Piquilloud, E Zogheib, M Jonas, F Grelon, I Runge, N Terzi, S Grangé, G Barberet, P G Guitard, J P Frat, A Constan, J M Chrétien, J Mancebo, A Mercat, J C M Richard, L Brochard, E Soilemezi, E Koco, S Savvidou, C Nouris, D Matamis, R Di Mussi, S Spadaro, C A Volta, M Mariani, A Colaprico, C Antonio, F Bruno, S Grasso, A Rodriguez, I Martín-Loeches, E Díaz, J R Masclans, F Gordo, J Solé-Violán, M Bodí, F X Avilés-Jurado, S Trefler, M Magret, L F Reyes, J Marín-Corral, J C Yebenes, A Esteban, A Anzueto, S Aliberti, M I Restrepo, J Skytte Larsson, B Redfors, S E Ricksten, R Haines, J Powell-Tuck, H Leonard, M Ostermann, R E Berthelsen, T S Itenov, A Perner, J U Jensen, M Ibsen, A E K Jensen, M H Bestle, T Bucknall, J Dixon, F Boa, I MacPhee, B J Philips, J Doyle, F Saadat, T Samuels, S Huddart, B McCormick, R DeBrunnar, J Preece, M Swart, C Peden, S Richardson, L Forni, P Kalfon, K Baumstarck, P Estagnasie, M A Geantot, A Berric, G Simon, B Floccard, T Signouret, M Boucekine, M Fromentin, M Nyunga, A Sossou, M Venot, R Robert, A Follin, A Renault, M Garrouste, O Collange, Q Levrat, I Villard, D Thévenin, J Pottecher, R G Patrigeon, N Revel, C Vigne, O Mimoz, P Auquier, S Pawar, T Jacques, K Deshpande, R Pusapati, B Wood, R A Pulham, J Wray, K Brown, C Pierce, S Nadel, P Ramnarayan, J R Azevedo, W S Montenegro, D P Rodrigues, S C Sousa, V F Araujo, A L Leitao, P H Prazeres, A V Mendonca, M P Paula, A Das Neves, C I Loudet, M Busico, D Vazquez, D Villalba, A Lischinsky, M Veronesi, M Emmerich, E Descotte, A Juliarena, M Carboni Bisso, M Grando, A Tapia, M Camargo, D Villani Ulla, L Corzo, H Placido Dos Santos, A Ramos, J A Doglia, E Estenssoro, M Carbonara, S Magnoni, C L Mac Donald, J S Shimony, V Conte, F Triulzi, F Stretti, M Macrì, A Z Snyder, N Stocchetti, D L Brody, V Podlepich, V Shimanskiy, I Savin, K Lapteva, A Chumaev, M C Tjepkema-Cloostermans, J Hofmeijer, A Beishuizen, H Hom, M J Blans, M J A M van Putten, L Longhi, B Frigeni, M Curinga, D Mingone, S Beretta, A Patruno, L Gandini, A Vargiolu, F Ferri, R Ceriani, M R Rottoli, L Lorini, G Citerio, S 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Regidor Sanz, M J Gómez Sánchez, S Aldunate Calvo, A N García Herrera, J Barado Hualde, O Agudo Pascual, J P Tirapu León, A Corona, C Ruffini, A Spazzadeschi, F Marrazzo, A Gandola, R Sciurti, C Savi, E Catena, M W Ke, C C Cheng, W C Huang, C H Chiang, W T Hung, K C Lin, S C Lin, S R Wann, K R Chiou, C J Tseng, P L Kang, G Y Mar, C P Liu, P Bertini, F De Sanctis, F Guarracino, P Bertini, R Baldassarri, F Guarracino, S H Buitinck, P H J van der Voort, J Oto, E Nakataki, Y Tsunano, M Izawa, N Tane, M Onodera, M Nishimura, S Ghosh, A Gupta, A De Gasperi, E Mazza, R Limuti, M Prosperi, N Bissenova, A Yergaliyeva, L Talan, G Yılmaz, G Güven, F Yoruk, N D Altıntas, D N Mukherjee, L K Agarwal, K Mandal, M Palomar, B Balsera, M Vallverdu, M Martinez, M Garcia, D Castellana, R Lopez, F Barcenilla, G E Kaminsky, R Carreño, A Escribá, M Fuentes, V Gálvez, R Del Olmo, B Nieto, C Vaquerizo, J Alvarez, M A De la Torre, E Torres, E Bogossian, S Aranha Nouer, D Ribeiro Salgado, S Carvalho Brugger, G Jiménez Jiménez, M Miralbés Torner, M Vallverdú Vidal, B Balsera Garrido, X Nuvials Casals, F Barcenilla Gaite, J Trujillano Cabello, M Palomar Martínez, M Doganci, S Izdes, S Guzeldag Besevli, A Alkan, B Kayaaslan, C Sánchez Ramírez, L Caipe Balcázar, M Cabrera Santana, M A Hernández Viera, S Hípola Escalada, C F Lübbe Vázquez, S M Marrero Penichet, F Artiles Campelo, M A De La Cal López, P Saavedra Santana, S Ruíz Santana, X Repessé, M Artiguenave, S Paktoris-Papine, F Espinasse, A Dinh, F El Sayed, C Charron, G Géri, A Vieillard-Baron, K Marmanidou, M Oikonomou, C Nouris, K Dimitroulakis, E Soilemezi, D Matamis, A Ferré, M Guillot, J L Teboul, D Lichtenstein, G Mézière, C Richard, X Monnet, T Pham, G Beduneau, F Schortgen, L Piquilloud, E Zogheib, M Jonas, F Grelon, I Runge, N Terzi, S Grangé, G Barberet, P G Guitard, J P Frat, A Constan, J M Chrétien, J Mancebo, A Mercat, J C M Richard, L Brochard, S Prīdāne, O Sabeļņikovs, F Mojoli, A Orlando, I Bianchi, F Torriglia, S Bianzina, M Pozzi, G A Iotti, A Braschi, G Beduneau, T Pham, F Schortgen, L Piquilloud, E Zogheib, M Jonas, F Grelon, I Runge, N Terzi, S Grangé, G Barberet, P G Guitard, J P Frat, A Constan, J M Chrétien, J Mancebo, A Mercat, J C M Richard, L Brochard, E Kondili, C Psarologakis, S Kokkini, V Amargianitakis, D Babalis, A Chytas, I Chouvarda, K Vaporidi, D Georgopoulos, O Trapp, A Kalenka, F Mojoli, A Orlando, I Bianchi, F Torriglia, S Bianzina, M Pozzi, G A Iotti, A Braschi, J A Benítez Lozano, P Carmona Sánchez, J E Barrueco Francioni, F Ruiz Ferrón, J M Serrano Simón, S Spadaro, D S Karbing, A Gioia, F Moro, F Dalla Corte, T Mauri, C A Volta, S E Rees, M V Petrova, R Mohan, A V Butrov, S D Beeharry, M V Vatsik, F I Sakieva, F Gobert, H Yonis, R Tapponnier, R Fernandez, M A Labaune, J F Burle, J Barbier, B Vincent, M Cleyet, J C Richard, C Guérin, C Righy Shinotsuka, J Creteur, F S Taccone, S Törnblom, S Nisula, S Vaara, M Poukkanen, S Andersson, V Pettilä, E Pesonen, Z Xie, X Liao, Y Kang, J Zhang, K Kubota, M Egi, S Mizobuchi, S Hegazy, A El-Keraie, E El Sayed, M Abd El Hamid, N J Rodrigues, M Pereira, I Godinho, J Gameiro, M Neves, J Gouveia, Z Costa E Silva, J A Lopes, J Mckinlay, M Kostalas, G Kooner, G Dudas, A Horton, C Kerr, N Karanjia, B Creagh-Brown, L Forni, A Yamazaki, M Sanz Ganuza, J A Martinez Molina, F Hidalgo Martinez, M T Chiquito Freile, N Garcia Fernandez, P Medrano Travieso, A Bandert, R Frithiof, M Lipcsey, D Smekal, P Schlaepfer, J D Durovray, V Plouhinec, C Chiappa, R Bellomo, A G Schneider, S Mitchell, J Durrant, H Street, E Dunthorne, J Shears, C Hernandez Caballero, R Hutchison, S Schwarze, S Ghabina, E Thompson, J R Prowle, C J Kirwan, C A Gonzalez, J L Pinto, V Orozco, J A Patiño, P K Garcia, K M Contreras, P Rodriguez, J E Echeverri
No abstract text is available yet for this article.
September 2016: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27678101/toward-understanding-myometrial-regulation-metabolomic-investigation-reveals-new-pathways-of-oxytocin-and-ritodrine-activity-on-the-myometrium
#13
Enitome E Bafor, Edward G Rowan, RuAngelie Edrada-Ebel
In recent times, additional pathways involved in the regulation of the myometrium have been suggested. This also holds true for the effect of drugs such as oxytocin (OT) and β-adrenergic agonists on the myometrium. Knowledge of these additional pathways will certainly prove useful in designing better therapies for pathologies of the myometrium. This study was therefore aimed at investigating the possibility of other pathways involved in the activities of both OT and ritodrine (RIT; a β-adrenergic agonist) in the myometrium by utilizing metabolomics and bioinformatics...
September 27, 2016: Reproductive Sciences
https://www.readbyqxmd.com/read/27629053/dietary-protein-intake-and-risk-of-type-2-diabetes-results-from-the-melbourne-collaborative-cohort-study-and-a-meta-analysis-of-prospective-studies
#14
Xianwen Shang, David Scott, Allison M Hodge, Dallas R English, Graham G Giles, Peter R Ebeling, Kerrie M Sanders
BACKGROUND: Reported associations between protein intake from different sources and type 2 diabetes (T2D) have been inconsistent. OBJECTIVE: We prospectively examined the relations of total, animal, and plant protein intakes with incident T2D. DESIGN: We followed 21,523 participants (women: 61.7%) between 1990 and 2007 from the Melbourne Collaborative Cohort Study who were free of diabetes, cardiovascular disease, cancer, and kidney stones at baseline...
September 14, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27620913/nt-probnp-and-exercise-capacity-in-adult-patients-with-congenital-heart-disease-and-a%C3%A2-prosthetic-valve-a%C3%A2-multicentre-prostava-study
#15
R C Schoonbeek, P G Pieper, Y J van Slooten, H G Freling, G T Sieswerda, A P J van Dijk, M R M Jongbloed, M C Post, B J Bouma, R M F Berger, T Ebels, J P van Melle
OBJECTIVES: N-terminal B‑type natriuretic peptide (NT-proBNP) is an important biomarker for the detection of heart failure. Adults with congenital heart disease (ACHD) and a prosthetic heart valve are at risk for heart failure. This study aimed to determine the value of NT-proBNP in ACHD patients with a prosthetic valve and investigate its relationship with cardiac function and exercise capacity. METHODS: In this multi-centre cross-sectional observational study, data regarding medical history, echocardiography, exercise testing (VO2peak) and laboratory blood evaluation (including NT-proBNP) were collected in ACHD patients with a single prosthetic valve (either homografts, heterografts or mechanical valves)...
November 2016: Netherlands Heart Journal
https://www.readbyqxmd.com/read/27553445/fractures-in-spina-bifida-from-childhood-to-young-adulthood
#16
A Trinh, P Wong, J Brown, S Hennel, P R Ebeling, P J Fuller, F Milat
: This study assessed the prevalence and types of fractures in spina bifida and examined risk factors for fracture. Fracture prevalence was highest in childhood and reduced in adolescence and young adulthood. The importance of maintaining mobility is highlighted by the increased risk of fracture in those who are non-ambulatory. INTRODUCTION: The aims of this study are to study the prevalence and types of fractures according to age group in spina bifida and examine risk factors associated with fracture...
August 24, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27540713/autosomal-dominant-osteopetrosis-associated-with-renal-tubular-acidosis-is-due-to-a-clcn7-mutation
#17
Sian E Piret, Caroline M Gorvin, Anne Trinh, John Taylor, Stefano Lise, Jenny C Taylor, Peter R Ebeling, Rajesh V Thakker
The aim of this study was to identify the causative mutation in a family with an unusual presentation of autosomal dominant osteopetrosis (OPT), proximal renal tubular acidosis (RTA), renal stones, epilepsy, and blindness, a combination of features not previously reported. We undertook exome sequencing of one affected and one unaffected family member, followed by targeted analysis of known candidate genes to identify the causative mutation. This identified a missense mutation (c.643G>A; p.Gly215Arg) in the gene encoding the chloride/proton antiporter 7 (gene CLCN7, protein CLC-7), which was confirmed by amplification refractory mutation system (ARMS)-PCR, and to be present in the three available patients...
November 2016: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/27459502/mothers-after-gestational-diabetes-in-australia-magda-a-randomised-controlled-trial-of-a-postnatal-diabetes-prevention-program
#18
Sharleen L O'Reilly, James A Dunbar, Vincent Versace, Edward Janus, James D Best, Rob Carter, Jeremy J N Oats, Timothy Skinner, Michael Ackland, Paddy A Phillips, Peter R Ebeling, John Reynolds, Sophy T F Shih, Virginia Hagger, Michael Coates, Carol Wildey
BACKGROUND: Gestational diabetes mellitus (GDM) is an increasingly prevalent risk factor for type 2 diabetes. We evaluated the effectiveness of a group-based lifestyle modification program in mothers with prior GDM within their first postnatal year. METHODS AND FINDINGS: In this study, 573 women were randomised to either the intervention (n = 284) or usual care (n = 289). At baseline, 10% had impaired glucose tolerance and 2% impaired fasting glucose. The diabetes prevention intervention comprised one individual session, five group sessions, and two telephone sessions...
July 2016: PLoS Medicine
https://www.readbyqxmd.com/read/27458948/screening-for-skin-cancer-us-preventive-services-task-force-recommendation-statement
#19
Kirsten Bibbins-Domingo, David C Grossman, Susan J Curry, Karina W Davidson, Mark Ebell, John W Epling, Francisco A R García, Matthew W Gillman, Alex R Kemper, Alex H Krist, Ann E Kurth, C Seth Landefeld, Carol M Mangione, William R Phillips, Maureen G Phipps, Michael P Pignone, Albert L Siu
IMPORTANCE: Basal and squamous cell carcinoma are the most common types of cancer in the United States and represent the vast majority of all cases of skin cancer; however, they rarely result in death or substantial morbidity, whereas melanoma skin cancer has notably higher mortality rates. In 2016, an estimated 76,400 US men and women will develop melanoma and 10,100 will die from the disease. OBJECTIVE: To update the 2009 US Preventive Services Task Force (USPSTF) recommendation on screening for skin cancer...
July 26, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27430315/long-term-prognosis-of-unrecognized-myocardial-infarction-detected-with-cardiovascular-magnetic-resonance-in-an-elderly-population
#20
Charlotte Ebeling Barbier, Raquel Themudo, Tomas Bjerner, Lars Johansson, Lars Lind, Håkan Ahlström
BACKGROUND: Individuals with unrecognized myocardial infarctions (UMIs) detected with cardiovascular magnetic resonance (CMR) constitute a recently defined group whose prognosis has not been fully evaluated. However, increasing evidence indicate that these individuals may be at considerable cardiovascular risk. The aim of the present study was to investigate the prognostic impact of CMR detected UMIs for major adverse cardiac events (MACE) in community living elderly individuals. METHODS: Late gadolinium enhancement CMR was performed in 248 randomly chosen 70-year-olds...
2016: Journal of Cardiovascular Magnetic Resonance
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