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https://www.readbyqxmd.com/read/29791984/-the-management-of-common-bile-duct-stones
#1
REVIEW
Chang Hwan Park
Common bile duct (CBD) stone is a relatively frequent disorder with a prevalence of 10-20% in patients with gallstones. This is also associated with serious complications, including obstructive jaundice, acute suppurative cholangitis, and acute pancreatitis. Early diagnosis and prompt treatment is the most important for managing CBD stones. According to a recent meta-analysis, endoscopic ultrasonography and magnetic resonance cholangiopancreatography have high sensitivity, specificity, and accuracy for the diagnosis of CBD stones...
May 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/29763444/cholelithiasis-and-choledocholithiasis-in-children-risk-factors-for-development
#2
Barbora Frybova, Jiri Drabek, Jindra Lochmannova, Ladislav Douda, Stepan Hlava, Daniela Zemkova, Vladimir Mixa, Martin Kyncl, Lubos Zeman, Michal Rygl, Radan Keil
PURPOSE: To compare anthropometric data (body mass index [BMI]) in patients without lithiasis to patients with symptomatic simple cholelithiasis or choledocholithiasis. METHODS: We retrospectively reviewed data from 147 patients undergoing laparoscopic cholecystectomy between 2001-2015. Complete growth data from 98 patients was compared with anthropometric data from the population of the Czech Republic and a control group (BMI of 100 consecutive patients without biliary stones in abdominal ultrasound who were admitted to a surgical department for suspected appendicitis)...
2018: PloS One
https://www.readbyqxmd.com/read/29760576/trends-of-gallbladder-cancer-in-jordan-over-2-decades-where-are-we
#3
Abdel Rahman Al Manasra, Mohammed Bani Hani, Haitham Qandeel, Samer Al Asmar, Mohammad Alqudah, Nabil Al-Zoubi, Satish Nadig, Shadi Hamouri, Khaled Obeidat, Nada Al-Muqaimi
Background and Study Aims: The prevalence of gallbladder cancer (GBC) varies between different parts of the world. This study is a review of literature and an update of a previously published study conducted in our university and aims to reassess the incidence of GBC over the past 2 decades. Patients and Methods: We conducted a retrospective study between 2002 and 2016. Data regarding demographics, clinical presentation, risk factors, histopathology, investigations, and treatments were obtained...
2018: Clinical Medicine Insights. Case Reports
https://www.readbyqxmd.com/read/29755896/bouveret-s-syndrome-literature-review
#4
REVIEW
Fady G Haddad, Wissam Mansour, Liliane Deeb
It was in 1896 that Bouveret's syndrome acquired its name after the French physician Leon Bouveret, who published two case reports in Revue de Medecin. Bouveret's syndrome describes gastric outlet obstruction secondary to an impacted gallstone. The gallstone reaches the small bowel through a bilioenteric fistula as a consequence of chronic inflammation and adherence between the biliary system and the bowels which increase the intraluminal pressure and leads to secondary wall ischemia and wall perforation with gallstone passage into the bowel...
March 10, 2018: Curēus
https://www.readbyqxmd.com/read/29736167/mechanisms-and-management-of-acute-pancreatitis
#5
REVIEW
Ari Garber, Catherine Frakes, Zubin Arora, Prabhleen Chahal
Acute pancreatitis represents a disorder characterized by acute necroinflammatory changes of the pancreas and is histologically characterized by acinar cell destruction. Diagnosed clinically with the Revised Atlanta Criteria, and with alcohol and cholelithiasis/choledocholithiasis as the two most prominent antecedents, acute pancreatitis ranks first amongst gastrointestinal diagnoses requiring admission and 21st amongst all diagnoses requiring hospitalization with estimated costs approximating 2.6 billion dollars annually...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29728459/abcg5-and-abcg8-more-than-a-defense-against-xenosterols
#6
Shailendra B Patel, Gregory Graf, Ryan Temel
The elucidation of the molecular basis of the rare disease Sitosterolemia has revolutionized our mechanistic understanding of how dietary sterols are excreted and how cholesterol is eliminated from the body. Two proteins ABCG5 and ABCG8, encoded by the Sitosterolemia locus, work as obligate dimers to pump sterols out of hepatocytes and enterocytes. ABCG5/ABCG8 are key in regulating whole-body sterol trafficking, by eliminating sterols via the biliary tree, as well as the intestinal tract. Importantly, these transporters keep xenosterols from accumulating in the body...
May 4, 2018: Journal of Lipid Research
https://www.readbyqxmd.com/read/29703854/evaluation-of-plasma-microrna-122-high-mobility-group-box-1-and-keratin-18-concentrations-to-stratify-acute-gallstone-disease-a-pilot-observational-cohort-study-in-an-emergency-general-surgery-unit
#7
Francesca Th'ng, Bastiaan Vliegenthart, Jonathan D Lea, Daniel J Antoine, James W Dear, Damian J Mole
OBJECTIVE: To obtain pilot data to evaluate the discriminatory power of biomarkers microRNA-122 (miR-122), high-mobility group box 1 (HMGB1), full-length keratin-18 (flk-18) and caspase-cleaved keratin-18 (cck-18) in plasma to identify potential biliary complications that may require acute intervention. DESIGN: An observational biomarker cohort pilot study. SETTING: In a Scottish University teaching hospital for 12 months beginning on 3 September 2014...
April 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29703649/index-versus-delayed-cholecystectomy-in-mild-gallstone-pancreatitis-results-of-a-randomized-controlled-trial
#8
Rozh Noel, Urban Arnelo, Lars Lundell, Folke Hammarqvist, Hanaz Jumaa, Lars Enochsson, Gabriel Sandblom
BACKGROUND: Delayed cholecystectomy is associated with increased risk of biliary events. The objectives of the study were to confirm the superiority of index cholecystectomy over delayed operation in mild gallstone pancreatitis. METHODS: Patients with mild gallstone pancreatitis were randomized into index-or delayed cholecystectomy (IC vs. DC). IC was performed within 48 h from randomization provided a stable or improved clinical condition. The primary outcome was gallstone-related events...
April 24, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29682244/is-there-a-correlation-between-helicobacter-pylori-and-enterohepatic-helicobacter-species-and-gallstone-cholecystitis
#9
Seyed Masih Fatemi, Abbas Doosti, Dariush Shokri, Sadegh Ghorbani-Dalini, Morteza Molazadeh, Hossein Tavakoli, Mohammad Minakari, Hamid Tavakkoli
BACKGROUND Cholecystitis is a common surgical condition. Recently, several authors have reported that DNA of bile tolerant Helicobacter spp. has been found in the human bile colonizing the biliary tract. The aim of this study was to evaluate the association between the presence of Helicobacter spp. and gallstone cholecystitis. METHODS In this case-control study, gallstones, bile, and gallbladder mucosa were collected from 25 patients without gallstone disease, 24 with acute cholecystitis, and 28 with chronic cholecystitis...
January 2018: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29656844/association-between-cholesterol-gallstones-and-testosterone-replacement-therapy-in-a-patient-with-primary-hypogonadism
#10
S Squarza, U G Rossi, P Torcia, M Cariati
A 16-year-old boy had a past medical history of primary hypogonadism, due to bilateral anorchia. He presented with gallstones located in the gallbladder and a mild dilatation of the intrahepatic biliary tree. The histology study reported cholesterol gallstones. The patient had been treated with testosterone replacement therapy since infancy. We suggest a possible correlation between testosterone replacement therapy and the presence of cholesterol gallstones.
April 12, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29644032/severe-acute-gallstone-pancreatitis-with-diffuse-hemorrhagic-gastritis
#11
Timothy J Harris, William C Beck, Avi Bhavaraju, Benjamin Davis, Mary K Kimbrough, Joseph C Jensen, Anna Privratsky, John R Taylor, Kevin W Sexton
A 67-year-old male presented with acute pancreatitis secondary to gallstones, also known as acute biliary pancreatitis, and subsequently developed gastric outlet obstruction and was transferred to our hospital. A gastro-jejunal feeding tube was placed and an open cholecystectomy was performed. The patient had a pancreatic drain placed for interval increase in pancreatic necrosis and then nearly exsanguinated from gastroduodenal artery pseudoaneurysm bleed. This was managed by coiling the gastroduodenal artery...
March 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29623887/clinical-and-biological-study-of-the-31-cases-of-gallstones
#12
Tayssir Nasri, Abderraouf Cherif, Youssef Gharbi, Ilhem Hellara, Mohamed Zili, Fadoua Neffati, Mohamed Fadhel Najjar
This study reports the clinical and biological signs, as well as the morphological aspect and the chemical composition of the calculus during the biliary stones. The study population consisted of 31 patients with an average age of 49 years (30 women and one man) with biliary lithiasis and who had cholecystectomy. Hepatic colic and epigastralgia were the most evocative clinical signs. The calculus were pigmentary (n=6), cholesterolic and mostly single (n=18), and mixed (n=6) and one infectious multiple lithiasis...
April 1, 2018: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/29616644/etiological-therapeutic-and-prognostic-particularities-of-primary-biliary-peritonitis-in-tropical-environments
#13
S Ouedraogo, M Windsouri, J T Sawadogo, M Zida, E Ouangre, S S Traore
To describe the etiological, therapeutic, and prognostic aspects of primary biliary peritonitis in Burkina Faso. This retrospective study reviewed records of all patients admitted for primary biliary peritonitis at Tenkodogo Regional Hospital (Burkina Faso) from 2010 through 2016. Cases of secondary biliary peritonitis have been excluded. Thirty patients were identified. Their average age was 26.5 years. Fourteen patients were under 12 years of age. The reasons for consultation were dominated by abdominal pain (in all cases) and bile-induced vomiting (in 22 cases)...
February 1, 2018: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29602557/colicky-pain-and-related-complications-after-cholecystectomy-for-mild-gallstone-pancreatitis
#14
David W da Costa, Nicolien J Schepers, Stefan A Bouwense, Bob A Hollemans, Eva Doorakkers, Djamila Boerma, Camiel Rosman, Cees H Dejong, Marcel B W Spanier, Hjalmar C van Santvoort, Hein G Gooszen, Marc G Besselink
BACKGROUND: Same-admission cholecystectomy is advised after gallstone pancreatitis to prevent recurrent pancreatitis, colicky pain and other complications, but data on the incidence of symptoms and complications after cholecystectomy are lacking. METHODS: This was a prospective cohort study during the previously published randomized controlled PONCHO trial on timing of cholecystectomy after mild gallstone pancreatitis. Data on healthcare consumption and questionnaires focusing on colicky pain and biliary complications were obtained during 6 months after cholecystectomy...
March 27, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29512023/rate-of-recurrence-in-indian-patients-presenting-with-acute-pancreatitis-and-identification-of-chronicity-on-follow-up-possible-risk-factors-for-progression
#15
Rishikesh Kalaria, Philip Abraham, Devendra C Desai, Anand Joshi, Tarun Gupta
BACKGROUND: To study the profile and long-term outcome of Indian patients presenting with acute pancreatitis and the possible risk factors for progression. METHODS: Consecutive patients with acute or recurrent acute pancreatitis seen in our department during July 2013 to December 2014 were included. Details of past episodes were collected and patients were followed up till March 2015. RESULTS: In the 97 patients included (mean age 47.2 [SD 16...
March 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29501782/bile-spillage-as-a-risk-factor-for-surgical-site-infection-after-laparoscopic-cholecystectomy-a-prospective-study-of-1-001-patients
#16
Thomas Peponis, Trine G Eskesen, Tomaz Mesar, Noelle Saillant, Haytham M A Kaafarani, D Dante Yeh, Peter J Fagenholz, Marc A de Moya, David R King, George C Velmahos
BACKGROUND: Bile spillage (BS) occurs frequently during laparoscopic cholecystectomy, yet its impact on postoperative outcomes remains unknown. We hypothesized that BS increases the risk of surgical site infections (SSI) after laparoscopic cholecystectomy. STUDY DESIGN: Patients older than 18, who were admitted to an academic hospital for a laparoscopic (or laparoscopic converted to open) cholecystectomy, from May 2010 to March 2017, were prospectively included...
March 2, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29487761/acute-cholangitis-an-update
#17
REVIEW
Monjur Ahmed
Acute cholangitis is bacterial infection of the extra-hepatic biliary system. As it is caused by gallstones blocking the common bile duct in most of the cases, its prevalence is greater in ethnicities with high prevalence of gallstones. Biliary obstruction of any cause is the main predisposing factor. Diagnosis is established by the presence of clinical features, laboratory results and imaging studies. The treatment modalities include administration of intravenous fluid, antibiotics, and drainage of the bile duct...
February 15, 2018: World Journal of Gastrointestinal Pathophysiology
https://www.readbyqxmd.com/read/29479416/need-brooks-no-delay-peritoneo-cutaneous-fistula-formation-secondary-to-gallstone-dropped-at-laparoscopic-cholecystectomy-20-years-previously-a-case-report
#18
Luke Nugent, Palanichamy Chandran
Dropped gallstones, in addition to inadvertent damage to the biliary tree, is a complication seen in laparoscopic cholecystectomy (LC) far more frequently than the open procedure. It can result in symptomatic abscess formation, and given its relative rarity, can present a diagnostic challenge. We present the case of a lady whose dropped gallstone resulted in a peritoneo-cutaneous fistula, over 20 years on from her LC.
February 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29472508/false-prolongation-of-international-normalized-ratio-associated-with-daptomycin
#19
Susan E Smith, Kelli A Rumbaugh
PURPOSE: Persistent elevation of prothrombin time (PT) and International Normalized Ratio (INR) values in a patient receiving daptomycin is reported. SUMMARY: A morbidly obese 51-year-old man was hospitalized for evaluation for surgical intervention for gallstone pancreatitis and biliary obstruction. Previously prescribed warfarin therapy was withheld due to suspected coagulopathy and an elevated INR (5.1), and warfarin reversal was initiated. After undergoing partial cholecystectomy on hospital day 6, the patient developed sepsis and was treated with i...
March 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29465584/duplication-of-the-extrahepatic-bile-duct-a-case-report-and-review-of-the-literatures
#20
REVIEW
Xiaoxiao Fan, Lifeng He, P Asutosh Khadaroo, Daizhan Zhou, Hui Lin
RATIONALE: Duplication of the extrahepatic bile duct is an extremely rare congenital anomaly of the biliary system. PATIENT CONCERNS: A 44-year-old woman presented with a history of continuous upper abdominal pain and vomiting. DIAGNOSES: Magnetic resonance cholangiopancreatography (MRCP) disclosed diffuse dilatation of the intrahepatic and extrahepatic bile ducts. Endoscopic retrograde cholangiopancreatography (ERCP) showed the presence of two extrahepatic bile ducts with calculus at the distal end of the CBD...
February 2018: Medicine (Baltimore)
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