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Cardiac mapping

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https://www.readbyqxmd.com/read/29222861/zero-fluoroscopy-permanent-pacemaker-implantation-using-ensite-navx-system-clinical-viability-or-fanciful-technique
#1
Ping Guo, Jie Qiu, Yan Wang, Guangzhi Chen, Riccardo Proietti, Al-Selmi Fadhle, Chunxia Zhao, Dao Wen Wang
BACKGROUND: Fluoroscopy is the imaging modality routinely used for cardiac device implantation and electrophysiological procedures. Due to the rising concern regarding the harmful effects of radiation exposure to both the patients and operation staffs, novel 3D mapping systems have been developed and implemented in electrophysiological procedure for the navigation of catheters inside the heart chambers. Their applicability in cardiac device implantation has been rarely reported. Our aim is to evaluate the feasibility and safety of permanent pacemaker implantation without fluoroscopy...
December 9, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29221272/goal-directed-fluid-restriction-using-stroke-volume-variation-and-cardiac-index-during-one-lung-ventilation-a-randomized-controlled-trial
#2
Hui Xu, Shu-Hua Shu, Di Wang, Xiao-Qing Chai, Yan-Hu Xie, Wei-De Zhou
Background: Goal-directed therapy confers a strong prognosis in patients undergoing major cardiac or noncardiac surgery. The present study investigated whether intraoperative goal-directed fluid restriction (GDFR) using stroke volume variation (SVV) and cardiac index could improve oxygenation and postoperative outcome in patients undergoing one-lung ventilation (OLV). Methods: A Total of 168 patients scheduled for elective thoracoscopic lobectomy under OLV were randomized into the GDFR protocol (group G) or conventional fluid therapy groups (group C)...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29216947/-effects-of-active-abdominal-compression-decompression-cpr-on-oxygen-metabolism-and-prognosis-in-patients-with-cardiac-arrest
#3
Xin Sha, Sisen Zhang, Hongwei Wang, Yingxin Cen, Wei Song, Jing Li, Lixiang Wang
OBJECTIVE: To analyze the effect of active abdominal compression-decompression cardiopulmonary resuscitation (AACD-CPR) and standard cardiopulmonary resuscitation (STD-CPR) on oxygen metabolism and prognosis of patient with cardiac arrest (CA), and to evaluate the treatment effect of AACD-CPR. METHODS: Patients with CA, CA time less than 30 minutes, and without STD-CPR and AACD-CPR contraindications admitted to the Zhengzhou People's Hospital from October 1st 2015 to May 31st 2017 were enrolled...
December 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29216303/three-dimensional-self-gated-cardiac-mr-imaging-for-the-evaluation-of-myocardial-infarction-in-mouse-model-on-a-3t-clinical-mr-system
#4
Xiaoyong Zhang, Bensheng Qiu, Zijun Wei, Fei Yan, Caiyun Shi, Shi Su, Xin Liu, Jim X Ji, Guoxi Xie
PURPOSE: To develop and assess a three-dimensional (3D) self-gated technique for the evaluation of myocardial infarction (MI) in mouse model without the use of external electrocardiogram (ECG) trigger and respiratory motion sensor on a 3T clinical MR system. METHODS: A 3D T1-weighted GRE sequence with stack-of-stars sampling trajectories was developed and performed on six mice with MIs that were injected with a gadolinium-based contrast agent at a 3T clinical MR system...
2017: PloS One
https://www.readbyqxmd.com/read/29213071/gwas-of-the-electrocardiographic-qt-interval-in-hispanics-latinos-generalizes-previously-identified-loci-and-identifies-population-specific-signals
#5
Raúl Méndez-Giráldez, Stephanie M Gogarten, Jennifer E Below, Jie Yao, Amanda A Seyerle, Heather M Highland, Charles Kooperberg, Elsayed Z Soliman, Jerome I Rotter, Kathleen F Kerr, Kelli K Ryckman, Kent D Taylor, Lauren E Petty, Sanjiv J Shah, Matthew P Conomos, Nona Sotoodehnia, Susan Cheng, Susan R Heckbert, Tamar Sofer, Xiuqing Guo, Eric A Whitsel, Henry J Lin, Craig L Hanis, Cathy C Laurie, Christy L Avery
QT interval prolongation is a heritable risk factor for ventricular arrhythmias and can predispose to sudden death. Most genome-wide association studies (GWAS) of QT were performed in European ancestral populations, leaving other groups uncharacterized. Herein we present the first QT GWAS of Hispanic/Latinos using data on 15,997 participants from four studies. Study-specific summary results of the association between 1000 Genomes Project (1000G) imputed SNPs and electrocardiographically measured QT were combined using fixed-effects meta-analysis...
December 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29209927/hydroxocobalamin-for-the-treatment-of-cardiac-surgery-associated-vasoplegia-a-case-series
#6
Pranav R Shah, Penny S Reynolds, Nirvik Pal, Daniel Tang, Harry McCarthy, Bruce D Spiess
PURPOSE: Vasoplegia is a clinical syndrome marked by severe arteriolar vasodilatation, hypotension, and low systemic vascular resistance refractory to multiple vasopressor treatment. We report our experience with hydroxocobalamin (B12) infusion as a potential rescue adjunct for refractory vasoplegia during cardiopulmonary bypass (CPB). METHODS: We performed a retrospective chart review of 33 patients undergoing cardiac surgery between 1 January 2013 and 31 December 2015, who were given intravenous B12 for refractory hypotension during, or immediately following, CPB...
December 5, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29206322/4d-flow-mri-cardiac-function-and-t1-mapping-association-of-valve-mediated-changes-in-aortic-hemodynamics-with-left-ventricular-remodeling
#7
Julia Geiger, Amir A Rahsepar, Kenichiro Suwa, Alex Powell, Ahmadreza Ghasemiesfe, Alex J Barker, Jeremy D Collins, James C Carr, Michael Markl
BACKGROUND: Patients with bicuspid aortic valve (BAV) show altered hemodynamics in the ascending aorta that can be assessed by 4D flow MRI. PURPOSE: Comprehensive cardiac MRI was applied to test the hypothesis that BAV-mediated changes in aortic hemodynamics (wall shear stress [WSS] and velocity) are associated with parameters of left ventricular (LV) remodeling. STUDY TYPE: Retrospective data analysis. POPULATION: Forty-nine BAV patients (mean age = 50...
December 5, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29204771/comparison-of-blood-pressure-monitoring-by-applanation-tonometry-and-invasively-assessed-blood-pressure-in-cardiological-patients
#8
G Greiwe, S Hoffmann, L Herich, M S Winkler, C J Trepte, C R Behem, M Petzoldt, D A Reuter, S A Haas
The aim of this study was to evaluate the accuracy and precision of non-invasive continuous blood pressure measurement by applanation tonometry (AT) in awake or anaesthetised cardiological intensive care patients. Patients suffering from highly impaired left ventricular function atrial fibrillation or severe aortic valve stenosis were included into the study. Arterial blood pressure was recorded by applanation tonometry (T-Line 400, Tensys Medical®, USA) and an arterial line in awake or anaesthetised patients...
December 4, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29202532/-premature-outflow-tract-ventricular-contraction-combined-with-complete-bundle-branch-block-the-characteristic-electrocardiographic-and-ablation-target-potential-features
#9
C Y Di, Z Wan, K Li, Y S Ding, W H Lin
Objective: To explore the characteristics of electrocardiogram(ECG) and target potential features of premature ventricular contraction (PVC) in patients with complete left/right bundle branch block (CL/RBBB) and compare with those without CL/RBBB. Methods: A retrospective analysis was done in 8 outflow tract PVC patients with CL/RBBB, who successfully underwent radiofrequency ablation from August 2009 to June 2017. According to the bundle branch block chamber, patients were divided into the complete right bundle branch block (CRBBB) group (n=4) and the complete left bundle branch block (CLBBB) group (n=4)...
December 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29197656/endocardial-infarct-scar-recognition-by-myocardial-electrical-impedance-is-not-influenced-by-changes-in-cardiac-activation-sequence
#10
Gerard Amorós-Figueras, Esther Jorge, Concepción Alonso-Martin, Daniel Traver, Maria Ballesta, Ramon Bragós, Javier Rosell-Ferrer, Juan Cinca
BACKGROUND: Measurement of myocardial electrical impedance can allow recognition of infarct scar and theoretically is not influenced by changes in cardiac activation sequence, but this is not known. OBJECTIVES: To evaluate the ability of endocardial electrical impedance measurements to recognize areas of infarct scar and to assess the stability of the impedance data under changes of cardiac activation sequence. METHODS: One month-old myocardial infarction confirmed by cardiac magnetic resonance (CMR) was induced in five pigs submitted to coronary artery catheter-balloon occlusion...
November 29, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29194738/cardiac-mr-elastography-using-reduced-fov-single-shot-spin-echo-epi
#11
Yi Sui, Shivaram Poigai Arunachalam, Arvin Arani, Joshua D Trzasko, Phillip M Young, James F Glockner, Kevin J Glaser, David S Lake, Kiaran P McGee, Armando Manduca, Phillip J Rossman, Richard L Ehman, Philip A Araoz
PURPOSE: To implement a reduced field of view (rFOV) technique for cardiac MR elastography (MRE) and to demonstrate the improvement in image quality of both magnitude images and post-processed MRE stiffness maps compared to the conventional full field of view (full-FOV) acquisition. METHODS: With Institutional Review Board approval, 17 healthy volunteers underwent both full-FOV and rFOV cardiac MRE scans using 140-Hz vibrations. Two cardiac radiologists blindly compared the magnitude images and stiffness maps and graded the images based on several image quality attributes using a 5-point ordinal scale...
December 1, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29194732/doppler-ultrasound-triggering-for-cardiac-mri-at-7t
#12
F Kording, C Ruprecht, B Schoennagel, K Fehrs, J Yamamura, G Adam, J Goebel, K Nassenstein, S Maderwald, H H Quick, O Kraff
PURPOSE: A prerequisite for cardiac MR (CMR) imaging is adequate synchronization of image acquisition with the cardiac cycle. Electrocardiogram triggering may be hampered by electromagnetic interferences at high field strength. The purpose of this work is to evaluate the feasibility of Doppler ultrasound triggering for CMR image synchronization at 7T ultra-high-field MRI. METHODS: A custom-built Doppler ultrasound (DUS) trigger device was developed. Magnetic resonance compatibility was evaluated using E- and H-field probes and flip angle maps prior to the study...
December 1, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29191206/optimized-cest-cardiovascular-magnetic-resonance-for-assessment-of-metabolic-activity-in-the-heart
#13
Zhengwei Zhou, Christopher Nguyen, Yuhua Chen, Jaime L Shaw, Zixin Deng, Yibin Xie, James Dawkins, Eduardo Marbán, Debiao Li
BACKGROUND: Previous studies have linked cardiac dysfunction to loss of metabolites in the creatine kinase system. Chemical exchange saturation transfer (CEST) is a promising metabolic cardiovascular magnetic resonance (CMR) imaging technique and has been applied in the heart for creatine mapping. However, current limitations include: (a) long scan time, (b) residual cardiac and respiratory motion, and (c) B0 field variations induced by respiratory motion. An improved CEST CMR technique was developed to address these problems...
November 30, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29190801/comparison-between-manual-and-mechanical-chest-compressions-during-resuscitation-in-a-pediatric-animal-model-of-asphyxial-cardiac-arrest
#14
Jorge López, Sarah N Fernández, Rafael González, María J Solana, Javier Urbano, Blanca Toledo, Jesús López-Herce
AIMS: Chest compressions (CC) during cardiopulmonary resuscitation are not sufficiently effective in many circumstances. Mechanical CC could be more effective than manual CC, but there are no studies comparing both techniques in children. The objective of this study was to compare the effectiveness of manual and mechanical chest compressions with Thumper device in a pediatric cardiac arrest animal model. MATERIAL AND METHODS: An experimental model of asphyxial cardiac arrest (CA) in 50 piglets (mean weight 9...
2017: PloS One
https://www.readbyqxmd.com/read/29188497/bexarotene-a-selective-rxr%C3%AE-agonist-reverses-hypotension-associated-with-inflammation-and-tissue-injury-in-a-rat-model-of-septic-shock
#15
Bahar Tunctan, Sefika P Kucukkavruk, Meryem Temiz-Resitoglu, Demet S Guden, Ayse N Sari, Seyhan Sahan-Firat
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that can activate or inhibit the expression of many target genes by forming a heterodimer complex with the retinoid X receptor (RXR). The aim of this study was to investigate effects of bexarotene, a selective RXRα agonist, on the changes in renal, cardiac, hepatic, and pulmonary expression/activity of inducible nitric oxide synthase (iNOS) and cytochrome P450 (CYP) 4F6 in relation to PPARα/β/γ-RXRα heterodimer formation in a rat model of septic shock...
November 29, 2017: Inflammation
https://www.readbyqxmd.com/read/29187679/cardiac-driven-pulsatile-motion-of-intracranial-cerebrospinal-fluid-visualized-based-on-a-correlation-mapping-technique
#16
Satoshi Yatsushiro, Saeko Sunohara, Naokazu Hayashi, Akihiro Hirayama, Mitsunori Matsumae, Hideki Atsumi, Kagayaki Kuroda
PURPOSE: A correlation mapping technique delineating delay time and maximum correlation for characterizing pulsatile cerebrospinal fluid (CSF) propagation was proposed. After proofing its technical concept, this technique was applied to healthy volunteers and idiopathic normal pressure hydrocephalus (iNPH) patients. METHODS: A time-resolved three dimensional-phase contrast (3D-PC) sampled the cardiac-driven CSF velocity at 32 temporal points per cardiac period at each spatial location using retrospective cardiac gating...
November 29, 2017: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/29184761/estimating-extraction-fraction-and-blood-flow-by-combining-first-pass-myocardial-perfusion-and-t1-mapping-results
#17
Devavrat Likhite, Promporn Suksaranjit, Ganesh Adluru, Brent Wilson, Edward DiBella
Background: Quantifying myocardial perfusion is complicated by the complexity of pharmacokinetic model being used and the reliability of perfusion parameter estimates. More complex modeling provides more information about the underlying physiology, but too many parameters in complex models introduce a new problem of reliable estimation. To overcome the problem of multiple parameters, we have developed a technique that combines knowledge from two different cardiac magnetic resonance (MR) imaging techniques: dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and T1 mapping...
October 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29183321/effects-of-controlled-hypoxemia-or-hypovolemia-on-global-and-intestinal-oxygenation-and-perfusion-in-isoflurane-anesthetized-horses-receiving-an-alpha-2-agonist-infusion
#18
Klaus Hopster, Liza Wittenberg-Voges, Florian Geburek, Charlotte Hopster-Iversen, Sabine B R Kästner
BACKGROUND: Aim of this prospective experimental study was to assess effects of systemic hypoxemia and hypovolemia on global and gastrointestinal oxygenation and perfusion in anesthetized horses. Therefore, we anesthetized twelve systemically healthy warmblood horses using either xylazine or dexmedetomidine for premedication and midazolam and ketamine for induction. Anesthesia was maintained using isoflurane in oxygen with either xylazine or dexmedetomidine and horses were ventilated to normocapnia...
November 28, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29181526/cortical-structures-associated-with-human-blood-pressure-control
#19
Nuria Lacuey, Johnson P Hampson, Wanchat Theeranaew, Bilal Zonjy, Ajay Vithala, Norma J Hupp, Kenneth A Loparo, Jonathan P Miller, Samden D Lhatoo
Importance: A better understanding of the role of cortical structures in blood pressure control may help us understand cardiovascular collapse that may lead to sudden unexpected death in epilepsy (SUDEP). Objective: To identify cortical control sites for human blood pressure regulation. Design, Setting, and Participants: Patients with intractable epilepsy undergoing intracranial electrode implantation as a prelude to epilepsy surgery in the Epilepsy Monitoring Unit at University Hospitals Cleveland Medical Center were potential candidates for this study...
November 27, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29177772/an-8-channel-tx-rx-dipole-array-combined-with-16-rx-loops-for-high-resolution-functional-cardiac-imaging-at-7%C3%A2-t
#20
Bart R Steensma, Ingmar J Voogt, Tim Leiner, Peter R Luijten, Jesse Habets, Dennis W J Klomp, Cornelis A T van den Berg, Alexander J E Raaijmakers
OBJECTIVE: To demonstrate imaging performance for cardiac MR imaging at 7 T using a coil array of 8 transmit/receive dipole antennas and 16 receive loops. MATERIALS AND METHODS: An 8-channel dipole array was extended by adding 16 receive-only loops. Average power constraints were determined by electromagnetic simulations. Cine imaging was performed on eight healthy subjects. Geometrical factor (g-factor) maps were calculated to assess acceleration performance. Signal-to-noise ratio (SNR)-scaled images were reconstructed for different combinations of receive channels, to demonstrate the SNR benefits of combining loops and dipoles...
November 24, 2017: Magma
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