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https://www.readbyqxmd.com/read/29166719/-clinical-characteristics-and-outcome-comparison-between-atrial-fibrillation-patients-underwent-catheter-ablation-under-general-aesthesia-or-local-anesthesia-and-sedation
#1
J J Xu, L J Gao, D Chang, X J Xiao, R F Zhang, J Lin, Z M Zhao, H Zhang, Y L Xia, X M Yin, Y Z Yang
Objective: To compare the outcome of radiofrequency catheter ablation under local anesthesia/sedation (S) or general anesthesia(GA) in atrial fibrillation patients. Methods: Data of 498 patients with atrial fibrillation undergoing radiofrequency catheter ablation in our departmentfrom January 2014 to December 2015 were retrospectively analyzed. Two hundred and twenty patients assigned to the GA group, the other 278 patients to the S group. Patients were followed clinically every 3 months within one year after procedure...
November 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29166711/-effects-of-caspase-1-inhibitor-vx765-on-cold-restraint-stress-induced-acute-gastric-ulcer-in-mice
#2
S Q Zheng, X D Hong, T S Chen, P F Luo, S C Xiao
Objective: To investigate the protective effects of caspase-1 inhibitor VX765 on gastric mucosa of mice with cold-restraint stress-induced acute gastric ulcer. Methods: Twenty-four specific pathogen free male C57BL/6J mice were divided into normal control group (NC), cold restrain group (CR), VX765 pre-treatment+ cold restrain group (VCR), and rabeprazole pre-treatment+ cold restrain group (RCR) according to the random number table, with 6 mice in each group. Mice in group NC were injected intraperitoneally with solution of 10 mL/kg dimethylsulfoxide (DMSO) and phosphate buffer solution (PBS)...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166447/prevalence-and-clinical-profile-of-chronic-pain-and-its-association-with-mental-disorders
#3
Flávia Garcia Pereira, Mariane Henriques França, Maria Cristina Alochio de Paiva, Laura Helena Andrade, Maria Carmen Viana
OBJECTIVE: To identify the prevalence of 12-month self-reported pain and chronic pain in a general population and to describe their clinical profile to assess if chronic pain is associated with 12-month mental disorders. METHODS: The data used comes from the São Paulo Megacity Mental Health Survey, a population-based study assessing adult (≥ 18 years) residents of the São Paulo metropolitan area, Brazil. We have assessed the respondents (n = 5,037) using the Composite International Diagnostic Interview (CIDI 3...
November 17, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29166361/the-impact-of-hepatectomy-time-of-the-liver-graft-on-post-transplant-outcome-a-eurotransplant-cohort-study
#4
Ina Jochmans, Steffen Fieuws, Ineke Tieken, Undine Samuel, Jacques Pirenne
OBJECTIVE: Assessing the effect of donor hepatectomy time on outcome after transplantation. SUMMARY OF BACKGROUND DATA: When blood supply in a deceased organ donor stops, ischemic injury starts. Livers are cooled to reduce cellular metabolism and minimize ischemic injury. This cooling is slow and livers are lukewarm during hepatectomy, potentially affecting outcome. METHODS: We used the Eurotransplant Registry to investigate the relationship between donor hepatectomy time and post-transplant outcome in 12,974 recipients of deceased-donor livers (January 1, 2004, to December 31, 2013)...
November 21, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29166252/low-intensity-exercise-accelerates-wound-healing-in-diabetic-mice
#5
Todd Keylock, Lee Meserve, Amber Wolfe
INTRODUCTION: Moderate-intensity aerobic exercise has been noted to improve wound healing rates in mice and people, but different intensities of exercise may have different impacts on healing rates. It is important to determine the most beneficial exercise intensity for improving wound healing in people with type 2 diabetes to help prevent wounds from becoming chronic, greatly reduce pain and immobility, and lower the high cost of health care associated with treatment. OBJECTIVE: The purpose of this study is to determine the impact of low-intensity exercise compared with high-intensity exercise in terms of the rate of wound healing in diabetic mice...
November 20, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29166203/temporal-profile-of-care-following-mild-traumatic-brain-injury-predictors-of-hospital-admission-follow-up-referral-and-six-month-outcome
#6
John K Yue, Ethan A Winkler, Sourabh Sharma, Mary J Vassar, Jonathan J Ratcliff, Frederick K Korley, Seth A Seabury, Adam R Ferguson, Hester F Lingsma, Sacha Meeuws, Opeolu M Adeoye, Jonathan W Rick, Caitlin K Robinson, Siena M Duarte, Esther L Yuh, Pratik Mukherjee, Sureyya S Dikmen, Thomas W McAllister, Ramon Diaz-Arrastia, Alex B Valadka, Wayne A Gordon, David O Okonkwo, Geoffrey T Manley
OBJECTIVE: To investigate the clinical management and medical follow-up of patients with mild traumatic brain injury (mTBI) presenting to emergency departments (EDs). METHODS: Overall, 168 adult patients with mTBI from the prospective, multicentre Transforming Research and Clinical Knowledge in TBI (TRACK-TBI) Pilot study with Glasgow Coma Scale (GCS) 13-15, no polytrauma and alive at six months were included. Predictors for hospital admission, three-month follow-up referral and six-month functional disability (Glasgow Outcome Scale-Extended (GOSE) ≤ 6) were analysed using multivariable regression...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29166129/initial-observations-of-intra-and-inter-fractional-motion-variation-in-mr-guided-lung-sbrt
#7
David H Thomas, Anand Santhanam, Amar U Kishan, Minsong Cao, James Lamb, Yugang Min, Dylan O'Connell, Yingli Yang, Nzhde Agazaryan, Percy Lee, Daniel Low
OBJECTIVE: To evaluate variations in intra- and inter-fractional tumor motion, and the effect on ITV contour accuracy, using deformable image registration of real-time 2D-sagital cine-mode MRI acquired during lung SBRT treatments. METHODS: Five lung tumor patients underwent free breathing SBRT treatments on the ViewRay system, with dose prescribed to a planning target volume (PTV; defined as a 3-6 mm expansion of the 4DCT-ITV). Sagittal slice cine-MR images (3.5x3...
November 22, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29165994/from-graphene-oxide-to-reduced-graphene-oxide-impact-on-physiochemical-and-mechanical-properties-of-graphene%C3%A2-cement-composites
#8
Aliakbar Gholampour, Meisam Valizadeh Kiamahalleh, Diana N H Tran, Togay Ozbakkaloglu, Dusan Losic
Graphene materials have been extensively explored and successfully used to improve performances of cement composites. These formulations were mainly optimized based on different dosages of graphene additives, but with lack of understanding how other parameters such as surface chemistry, size, charge, and defects of graphene structures could impact on physiochemical and mechanical properties of final material. This paper presents the first experimental study to evaluate the influence of oxygen functional groups of graphene and defectiveness of graphene structures on the axial tension and compression properties of graphene-cement mortar composites...
November 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29165855/physical-activity-coaching-by-australian-exercise-physiologists-is-cost-effective-for-patients-referred-from-general-practice
#9
Ben Ewald, Fiona Stacey, Natalie Johnson, Ronald C Plotnikoff, Elizabeth Holliday, Wendy Brown, Erica L James
OBJECTIVE: Interventions to promote physical activity for sedentary patients seen in general practice may be a way to reduce the burden of chronic disease. Coaching by an exercise physiologist is publicly funded in Australia, but cost effectiveness has not been documented. METHODS: In a three-arm randomised controlled trial, face-to-face coaching and telephone coaching over 12 weeks were compared with a control group using the outcome of step count for one week at baseline, three months and twelve months...
November 22, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/29165540/mobile-application-removes-societal-barriers-to-p4-medicine
#10
J-P Michel
The overlap between one innovative paradigm (P4 medicine: predictive, personalized, participatory and preventive) and another (a new definition of "Healthy ageing") is fertile ground for new technologies; a new mobile application (app) that could broaden our scientific knowledge of the ageing process and help us to better analyse the impact of possible interventions in slowing the ageing decline. A novel mobile application is here presented as a game including questions and tests will allow in 10 minutes the assessment of the following domains: robustness, flexibility (lower muscle strength), balance, mental and memory complaints, semantic memory and visual retention...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165408/-mitomycin-c-after-endoscopic-endonasal-dacryocystorhinostomy
#11
E L At'kova, G V Ramenskaya, A O Root, N N Krakhovetskiy, V D Yartsev, S D Yartsev, A E Petukhov, I E Shokhin
Mitomycin-C (MMC) is the most frequently used agent for prevention of excessive scarring at the osteotomy site after endoscopic endonasal dacryocystorhinostomy (EEDCR), which, however, being applied during the final stage of the surgery, shows questionable effectiveness. AIM: to evaluate the effectiveness of a new administration route of mitomycin C in EEDCR. MATERIAL AND METHODS: The study included 86 patients (95 cases) in the age range of 62.3±9 years with primary acquired nasolacrimal duct obstruction...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29161979/clinical-characteristics-of-intravenous-peg-asparaginase-hypersensitivity-reactions-in-patients-undergoing-treatment-for-acute-lymphoblastic-leukemia
#12
Emily K Browne, Christina Moore, April Sykes, Zhaohua Lu, Sima Jeha, Belinda N Mandrell
BACKGROUND: Asparaginase poses a substantial risk for hypersensitivity reactions during and after administration; however, these reactions vary by asparaginase formulation and administration route. It is imperative that nurses be knowledgeable of clinical symptoms associated with intravenous (IV) monomethoxypolyethylene glycol (PEG)-asparaginase reactions, as well as potential reaction timing. PURPOSE: This single institution retrospective study describes the clinical factors among patients with IV PEG-asparaginase hypersensitivity reactions...
November 1, 2017: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/29161977/coordinated-care-organizations-neonatal-and-infant-outcomes-in-oregon
#13
S Marie Harvey, Lisa P Oakley, Jangho Yoon, Jeff Luck
In 2012, Oregon's Medicaid program implemented a comprehensive accountable care model delivered through coordinated care organizations (CCOs). Because CCOs are expected to improve utilization of services and health outcomes, neonatal and infant outcomes may be important indicators of their impact. Estimating difference-in-differences models, we compared prepost CCO changes in outcomes (e.g., low birth weight, abnormal conditions, 5-minute Apgar score, congenital anomalies, and infant mortality) between Medicaid and non-Medicaid births among 99,924 infants born in Oregon during 2011 and 2013...
November 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29161899/how-long-should-routine-eeg-be-recorded-to-get-relevant-information
#14
Hannah Doudoux, Kristina Skaare, Thomas Geay, Philippe Kahane, Jean L Bosson, Cécile Sabourdy, Laurent Vercueil
OBJECTIVE: The optimal duration of routine EEG (rEEG) has not been determined on a clinical basis. This study aims to determine the time required to obtain relevant information during rEEG with respect to the clinical request. METHOD: All rEEGs performed over 3 months in unselected patients older than 14 years in an academic hospital were analyzed retrospectively. The latency required to obtain relevant information was determined for each rEEG by 2 independent readers blinded to the clinical data...
March 1, 2017: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/29161805/robot-assisted-radical-cystectomy-with-totally-intracorporeal-urinary-diversion-initial-single-surgeon-s-experience-after-a-modified-modular-training
#15
Angelo Porreca, Francesco Chessa, Daniele Romagnoli, Antonio Salvaggio, Angelo Cafarelli, Marco Borghesi, Lorenzo Bianchi, Matteo Dandrea, Daniele D'Agostino, Donato Dente, Emanuele Cappa, Peter Wiklund, Eugenio Brunocilla, Riccardo Schiavina
BACKGROUND: To report the perioperative and early functional outcomes of patients undergoing Robot-assisted radical cystectomy (RARC) with totally intracorporeal urinary diversion performed by a single surgeon after a modified modular training. METHODS: The surgeon (A.P.) attained a 30-days modified modular training at a referring Centre mentored by a worldwide-recognized robotic surgeon (P.W.). The training program consisted of: a) e-learning based on 10 hours of theoretical lessons made by the mentor; b) video-session concerning the different steps of the procedure, c) step-by-step in vivo modular training...
November 21, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29161688/plasma-beta-trace-protein-as-a-marker-of-residual-renal-function-the-effect-of-different-hemodialysis-modalities-and-intra-individual-variability-over-time
#16
Amaryllis H van Craenenbroeck, Ann-Christin Bragfors-Helin, Abdul Rashid Qureshi, Bengt Lindholm, Bodil Sjöberg, Björn Anderstam, Olof Heimburger, Peter Stenvinkel, Peter Bárány
BACKGROUND/AIMS: Beta-trace protein (BTP) is a low-molecular-weight molecule, which may be used to assess residual renal function (RRF) in dialysis patients. Here we evaluated the influence of hemodialysis (HD) and hemodiafiltration (HDF) on plasma BTP, and analyzed the inter- and intra-individual variability of plasma BTP over time in HD and peritoneal dialysis (PD) patients. METHODS: In 12 prevalent HD patients, the effect of a single session of low-flux HD, high-flux HD and HDF on plasma BTP was studied...
November 22, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29161264/proprioceptive-assessment-in-clinical-settings-evaluation-of-joint-position-sense-in-upper-limb-post-stroke-using-a-robotic-manipulator
#17
Sara Contu, Asif Hussain, Simone Kager, Aamani Budhota, Vishwanath A Deshmukh, Christopher W K Kuah, Lester H L Yam, Liming Xiang, Karen S G Chua, Lorenzo Masia, Domenico Campolo
Proprioception is a critical component for motor functions and directly affects motor learning after neurological injuries. Conventional methods for its assessment are generally ordinal in nature and hence lack sensitivity. Robotic devices designed to promote sensorimotor learning can potentially provide quantitative precise, accurate, and reliable assessments of sensory impairments. In this paper, we investigate the clinical applicability and validity of using a planar 2 degrees of freedom robot to quantitatively assess proprioceptive deficits in post-stroke participants...
2017: PloS One
https://www.readbyqxmd.com/read/29160925/effects-of-swaddled-and-traditional-tub-bathing-methods-on-crying-and-physiological-responses-of-newborns
#18
Sinem Yalnızoğlu Çaka, Duygu Gözen
PURPOSE: The purpose of this study was to examine the effects of two bathing methods on crying duration and physiological measurements of newborns. DESIGN AND METHODS: A randomized trial design was used in this study. The sample consisted of newborns (n = 80) who were admitted to neonatal intensive care unit of a university hospital located in a large city. The groups were determined as swaddled bathing (SB) (n = 40) and traditional tub bathing (TTB) (n = 40) by using random number table...
November 21, 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/29160851/development-of-an-impedimetric-aptasensor-for-the-detection-of-staphylococcus-aureus
#19
Peggy Reich, Regina Stoltenburg, Beate Strehlitz, Dieter Frense, Dieter Beckmann
In combination with electrochemical impedance spectroscopy, aptamer-based biosensors are a powerful tool for fast analytical devices. Herein, we present an impedimetric aptasensor for the detection of the human pathogen Staphylococcus aureus. The used aptamer targets protein A, a surface bound virulence factor of S. aureus. The thiol-modified protein A-binding aptamer was co-immobilized with 6-mercapto-1-hexanol onto gold electrodes by self-assembly. Optimization of the ratio of aptamer to 6-mercapto-1-hexanol resulted in an average density of 1...
November 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29160616/evaluation-of-microtitre-plate-based-haemoglobin-estimation
#20
A P Shah, P T Patel, B P Patel, K K Mishra, K Ghosh
INTRODUCTION: Haemoglobin estimation is one of the most important clinical investigations. Many techniques are available to measure haemoglobin; still there is a need for a haemoglobin assay technique which is cheap, robust and simple and can be used in field conditions very quickly using figure prick sample. We evaluated a cyanmethaemoglobin-based haemoglobin estimation using a microtitre plates for the purpose. METHODS: Microtitre plate-based haemoglobin estimation was developed using cyanmethaemoglobin-based assay and was compared with standard haematology analyser-based haemoglobin estimation in a large number of samples from a population of voluntary blood donors...
November 21, 2017: International Journal of Laboratory Hematology
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