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oral oncology, oral cancer, head neck cancer, reconstruction

K-L Bruchhage, A Leichtle, B Wollenberg
BACKGROUND: Reconstruction of defects after extirpation of head and neck cancer is a highly challenging and complex surgical undertaking. Commonly used techniques, e.g., the radial forearm flap, the anterior lateral thigh flap, or flaps harvested from the chest-deltopectoral or pectoralis major-share numerous disadvantages, such as donor-site morbidity, poor color matching for cutaneous reconstruction, and excessive tissue bulk. The use of a supraclavicular artery island flap is a long-forgotten but increasingly popular option for reconstruction in the head and neck area...
August 15, 2016: HNO
Ákos Bicsák, Alice Jellen, Herwig Tuppy, Wolfgang Paul Poeschl
BACKGROUND: Oral squamous cell carcinoma is the sixth most frequent malignancy in Austria. The incidence of arrhythmogenic right ventricle dysplasia (ARVC), an important cause of sudden cardiac death, is estimated at 1:5000 to 1:1000. CASE REPORT: We present a case of a 75-year-old woman who underwent major oncologic surgery for T4aN0M0 maxillary squamous cell carcinoma and reconstruction with a scapular-latissimus dorsi microvascular flap. The patient died suddenly during her postoperative care...
June 29, 2016: Oral and Maxillofacial Surgery
Anaeze C Offodile, Kai-Ping Chang, Hsin-Hung Chen, Eric Loesch, Shao-Yu Hung, Huang-Kai Kao
BACKGROUND: This study was a robust examination of the clinical outcomes and technical feasibility of sequential microvascular reconstruction for recurrent or second primary oral cancer. METHODS: A retrospective, cross-sectional analysis of adult patients undergoing microvascular reconstruction of head and neck oncologic defects was performed at Chang Gung Memorial Hospital, spanning 10 years. The patients were divided into three groups as follows: first episode, second episode, and third or more episodes of reconstruction...
October 2016: Annals of Surgical Oncology
Bin Zhang, Dangui Yan, Yabing Zhang, Xiwei Zhang, Hanfeng Wan
OBJECTIVE: To evaluate the efficacy of pedicled supraclavicular artery island flaps for head and neck reconstruction. METHODS: Reconstructive surgeries for head and neck oncologic defects were performed with the pedicled supraclavicular artery island flaps in 10 patients from May 2013 to December 2014 and the cases were review. Among them, 6 were performed for hypopharyngeal cancer, 2 for oral tongue cancer, 1 for oral base cancer and 1 for cervical esophageal cancer...
June 2015: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Amar Miglani, Viraj M Patel, Carrie S Stern, Katie E Weichman, Missak Haigentz, Thomas J Ow, Evan S Garfein
Background Surgical management of head and neck cancer is resource intensive and physiologically demanding. In patients with incurable disease, although the indications for surgery are not well defined, palliative benefit can be significant. The goal of this investigation was to compare outcomes of patients who underwent resection and reconstruction of head and neck cancer with curative intent with those who underwent similar procedures with palliative intent. Methods A retrospective review of patients who underwent reconstruction for head and neck cancer between 2008 and 2014 was conducted...
March 2016: Journal of Reconstructive Microsurgery
Steven B Chinn, Jeffrey N Myers
Oral cavity carcinoma (OCC) remains a major cause of morbidity and mortality in patients with head and neck cancer. Although the incidence has decreased over the last decade, outcomes remain stagnant with only a 5% improvement in overall survival in the last 20 years. Although surgical resection remains the primary treatment modality, several areas of controversy exist with regard to work-up, management of the primary and neck tumors, and adjuvant therapy. As surgical techniques evolve, so has the delivery of radiotherapy and systemic treatment, which have helped to improve the outcomes for patients with advanced disease...
October 10, 2015: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Silvano Ferrari, Andrea Ferri, Bernardo Bianchi, Andrea Varazzani, Francesco Giovacchini, Enrico Sesenna
BACKGROUND: Buccinator myomucosal flaps are routinely used for oral cavity reconstruction and are indicated mainly in patients classified as having stage N0 cancer. This purpose of this study was to investigate whether preservation of the vascular pedicle of the flap (facial artery and vein) during stadiative neck dissection alters the oncologic safety in these patients. METHODS: Fifty patients underwent resection of T1 to 3, N0 squamous cell carcinoma of the tongue or floor of the mouth, stadiative neck dissection, and reconstruction with a facial artery musculomucosal (FAMM) flap were retrospectively analyzed concerning rate of occult neck metastasis and recurrences...
April 2016: Head & Neck
Karl K Cuddy, Graham Cobb
BACKGROUND: Oral, lip and oropharyngeal cancer accounts for up to 75% of head and neck cancers. Dental professionals contribute to improved treatment outcomes through early detection of these cancers. Oral and maxillofacial surgeons (OMFS) are trained to participate in numerous phases of care for patients with oral, lip and oropharyngeal cancer. OBJECTIVE: To quantify the participation of Ontario OMFS in various phases of oral, lip and oropharyngeal cancer care...
2015: Journal—Canadian Dental Association, Journal de L'Association Dentaire Canadienne
Piriya Boonsiriphant, Joel A Hirsch, Alex M Greenberg, Eric M Genden
The restoration of function after oncologic surgery of the oral cavity constitutes one of the major challenges facing head and neck oncology. Within the general objective of securing esthetic as well as functional reconstructions, dental rehabilitation is crucial for achieving a good outcome. Adequate dental rehabilitation allows the patient to chew food and considerably improves speech and swallowing. These reconstructions will be driven biologically or prosthetically following surgical design and outcome.
May 2015: Oral and Maxillofacial Surgery Clinics of North America
Cédric S Pierre, Olivier Dassonville, Emmanuel Chamorey, Gilles Poissonnet, Jean-Christophe Riss, Marc Ettaiche, Frédéric Peyrade, Karen Benezery, Marie-Eve Chand, Axel Leyssalle, Anne Sudaka, Juliette Haudebourg, José Santini, Alexandre Bozec
CONCLUSIONS: Surgery for oral or oropharyngeal cancer with free-flap reconstruction is associated with moderate but persistent functional and quality of life (QoL) problems. Patient age, tumor stage, tumor site, and radiotherapy were the main predictors of functional outcome. OBJECTIVES: To evaluate long-term functional outcomes and QoL, and to determine their predictive factors in patients with oral or oropharyngeal cancer after oncologic surgery and free-flap reconstruction...
October 2014: Acta Oto-laryngologica
Nitin Bhola, Anendd Jadhav, Rajiv Borle, Gaurav Khemka, Sanatan Kumar, Harshit Shrivastava
INTRODUCTION: Reconstruction of full-thickness defects of the head and neck is a challenge. In this clinical study, we assessed the role of the bilobed/bipaddled pectoralis major myocutaneous flap (PMMF) for the reconstruction of large full-thickness defects of the cheek, after resection of oral cancer. MATERIALS AND METHOD: After resection of oral cancer, 62 cases of through-and-through defects of the oral cavity were reconstructed using folded/bipaddled/bilobed PMMF flap...
June 2015: Oral and Maxillofacial Surgery
Todd C Hanna, W Stuart McKenzie, Jon D Holmes
PURPOSE: This study describes the use of a full-thickness skin graft (FTSG) from the neck to cover the radial forearm free flap (RFFF) donor site in patients undergoing neck dissection and microvascular reconstruction for ablative head and neck oncologic surgery. The authors propose that an FTSG from the neck provides sufficient tissue quantity and quality, fewer surgical sites, and decreased surgical time and cost compared with other FTSG harvest sites and split-thickness skin grafts (STSGs)...
October 2014: Journal of Oral and Maxillofacial Surgery
Antonia Kolokythas
OBJECTIVES: Surgery remains the preferred treatment for the majority of oral cancers. The aim of the present article was to provide a comprehensive review of complications associated with surgical treatment of oral cancer including hardware failure; complications associated with choice of reconstruction, donor site morbidity as well as functional and aesthetic issues that impact on the quality of life. MATERIAL AND METHODS: The available English language literature relevant to complications associated with surgical treatment of oral cancer was reviewed...
2010: Journal of Oral & Maxillofacial Research
A Deganello, G Gitti, G Parrinello, E Muratori, G Larotonda, O Gallo
Reconstructive surgery of the head and neck region has undergone tremendous advancement over the past three decades, and the success rate of free tissue transfers has risen to greater than 95%. It must always be considered that not all patients are ideal candidates for free flap reconstruction, and also that not every defect strictly requires a free flap transfer to achieve good functional results. At our institution, free flap reconstruction is first choice, although we use pedicled alternative flaps for most weak patients suffering from severe comorbidities, and for pretreated patients presenting a second primary or a recurrent cancer...
December 2013: Acta Otorhinolaryngologica Italica
Emanuele Checcoli, Chiara Bianchini, Andrea Ciorba, Marco Candiani, Carlo Riberti, Stefano Pelucchi, Antonio Pastore
AIMS: The aim of this retrospective study is to review the experience in performing head and neck reconstruction surgery between 1989 and 2009 at the ENT Department of the University Hospital of Ferrara, Italy, considering the oncological as well as the functional and psychological outcome. METHODS AND STUDY DESIGN: Thirty-three consecutive patients were enrolled. Patients underwent flap reconstruction following primary or salvage surgery for squamous cell carcinoma of the oral cavity or oropharynx...
July 2013: Tumori
Jordan P Sand, Natalia A Kokorina, Stanislav O Zakharkin, James S Lewis, Brian Nussenbaum
OBJECTIVE: Preclinical data show that exogenous administration of recombinant human bone morphogenetic protein-2 (rhBMP-2) to human oral carcinoma cell lines increases pathogenicity using a nude mouse model. The objectives of this study are to (1) describe the characteristics of baseline protein expression of BMP-2 in head and neck squamous cell carcinomas (HNSCC) and (2) determine if BMP-2 expression level correlates with worse oncologic outcomes. STUDY DESIGN: Retrospective analysis of previously harvested patient samples...
February 2014: Otolaryngology—Head and Neck Surgery
Maciej J Mazurek, Maciej Rysz, Janusz Jaworowski, Filip Nowakowski, Romuald Krajewski, Stanisław Starościak, Marek Pietras, Hanna Polowniak-Pracka, Artur Włodarczyk
BACKGROUND: The purpose of this study was to determine the timing and type of surgical field contamination in 50 consecutive resections for advanced head and neck cancer with same-stage tissue reconstruction and to analyze the relationship between contamination and the surgical site infection. METHODS: Swabs from the surgical field and from surgical drapes close to the field were taken every 2 hours (at 0 hour, 2 hours, 4 hours, and 6 hours) and sent for a standard microbiological diagnostic procedure...
October 2014: Head & Neck
Margaret J Coyle, Robert Tyrrell, Andrew Godden, Ceri W Hughes, Charles Perkins, Steve Thomas, Daryl Godden
In maxillofacial head and neck oncology, tracheostomy is often used to secure the airway, but not without risk. This study compared the existing practice of two units: one where tracheostomy was routinely done with one where overnight intubation was used. From both units we retrospectively analysed 50 consecutive patients who had intraoral resection, neck dissection, and microvascular reconstruction for head and neck cancer. When compared with tracheostomy, overnight intubation resulted in a shorter mean stay in the intensive therapy unit (ITU) (1...
September 2013: British Journal of Oral & Maxillofacial Surgery
Cédric S Pierre, Olivier Dassonville, Emmanuel Chamorey, Gilles Poissonnet, Marc Ettaiche, José Santini, Frédéric Peyrade, Karen Benezery, Anne Sudaka, Alexandre Bozec
The aims of this study were to evaluate long-term quality of life (QoL) and to determine its predictive factors after oncologic surgery and free flap reconstruction in patients with oral or oropharyngeal cancer. Patients treated at our institution between 2000 and 2009, who are alive and disease-free at least 1 year after therapy, completed the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire and the specific H&N35 module. Eighty patients were included in our study. Global QoL score was 69...
April 2014: European Archives of Oto-rhino-laryngology
B L'Heureux-Lebeau, A Odobescu, P G Harris, L Guertin, A M Danino
BACKGROUND: Ablation of locally advanced head and neck cancers generally results in large composite oro-facial defects. Due to the often-large segment of mandible missing, as well as the need to provide skin coverage and oral lining, reconstructive options are limited. We present our experience in oncologic head and neck reconstruction using chimaeric subscapular system free flaps. METHODS: We performed a retrospective chart review of patients presenting important through-and-through oro-facial defects following ablation of T3, T4a or T4b tumours in two university centres between 2005 and 2011...
July 2013: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
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