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https://www.readbyqxmd.com/read/29786136/temporal-trends-in-the-epidemiology-of-cervical-cancer-in-south-africa-1994-2012
#1
Gbenga Olorunfemi, Ntombizodwa Ndlovu, Gwinyai Masukume, Admire Chikandiwa, Pedro T Pisa, Elvira Singh
Cervical cancer (CC) is the leading cause of cancer death among female South Africans (SA). Improved access to reproductive health services following multi-ethnic democracy in 1994, HIV epidemic, and the initiation of CC population-based screening in early 2000's have influenced the epidemiology of CC in SA. We therefore evaluated the trends in CC age-standardized incidence (ASIR) (1994 - 2009) and mortality rates (ASMR) (2004 - 2012) using data from the South African National Cancer Registry and the Statistics South Africa, respectively...
May 22, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29783992/a-review-of-the-risk-factors-genetics-and-treatment-of-endometriosis-in-chinese-women-a-comparative-update
#2
REVIEW
Yi Dai, Xiaoyan Li, Jinghua Shi, Jinhua Leng
Endometriosis is one of the major causes of economic burden and compromised quality of life in a very large percentage of Asian women. While it is perceived as a benign condition, recent research has shown that it may be a significant cause of infertility and metastatic cancer. It has also been associated with other diseases linked to the functioning of the immune system. Genetic as well as environmental factors are known to affect the manifestation and progression of endometriosis. This review aims to summarize recent research pertaining to the risk factors, diagnosis and treatment of endometriosis in Chinese women...
May 21, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29782363/regional-lymph-node-metastases-in-groin-sarcomas-a-diagnostic-and-therapeutic-challenge
#3
Deanna Wan Jie Ng, Ye Xin Koh, Grace Hwei Ching Tan, Khee Chee Soo, Melissa Ching Ching Teo
INTRODUCTION: The evaluation of lymph nodes and the role of groin dissection for groin sarcomas has been controversial where there have not been previous studies or guidelines published. In this study, we aim to first formulate a clinical approach in the evaluation of regional lymph nodal metastases. Second, we aim to also evaluate the role of regional lymphadenectomy in the setting of pathologically involved regional lymph nodes for groin sarcomas. MATERIALS AND METHODS: In total, 43 consecutive patients with groin sarcomas underwent treatment at the National Cancer Centre Singapore between 2002 and 2015...
May 18, 2018: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29782194/five-common-functional-polymorphisms-in-micrornas-and-susceptibility-to-breast-cancer-an-updated-meta-analysis
#4
Jie Wu, Yusi Wang, Lihua Shang, Lichun Qi, Mowei Song
AIMS: microRNAs (miRNA) play a key role in the pathogenesis of breast cancer (BC) as regulators of tumor-associated genes, and understanding their polymorphisms is critical to the control of breast carcinogenesis. Thus, the present study explored the association between five common functional polymorphisms in miRNAs (i.e., miRNA-196a2C>T, rs11614913; miRNA-146aG>C, rs2910164; miRNA-423C>A, rs6505162; miRNA-608G>C, rs4919510; miRNA-27aC>T, rs895819) and the risk of BC. MATERIALS AND METHODS: Meta-analyses were performed on 31 studies, including 14,677 BC patients and 16,143 cancer-free controls...
May 21, 2018: Genetic Testing and Molecular Biomarkers
https://www.readbyqxmd.com/read/29781465/hpv-literacy-the-role-of-english-proficiency-in-korean-american-immigrant-women
#5
Hee Yun Lee, Y Joon Choi, Young Ji Yoon, Jennifer Oh
BACKGROUND: Although Korean American women have one of the highest cervical cancer incidence and mortality rates among all Asian American and non-Hispanic White women, they are less likely to receive the human papillomavirus (HPV) vaccine to prevent cervical cancer. OBJECTIVES: This study aimed to examine Korean American women's HPV literacy and factors related to HPV literacy to identify targeted intervention strategies. METHODS: A quota sampling strategy was used to recruit 243 Korean American women aged 19-85 years in the Atlanta, Georgia, metropolitan area...
June 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29778607/cost-effectiveness-of-gastric-cancer-screening-according-to-race-and-ethnicity
#6
Monica Saumoy, Yecheskel Schneider, Nicole Shen, Michel Kahaleh, Reem Z Sharaiha, Shailja C Shah
BACKGROUND & AIMS: There are marked racial and ethnic differences in noncardia gastric cancer prevalence within the United States (US). Although gastric cancer screening is recommended in regions of high prevalence, screening is not routinely performed in the US. Our objective was to determine whether selected noncardia gastric cancer screening for high-risk races and ethnicities within the US is cost effective. METHODS: We developed a decision analytic Markov model with the base case of a 50-year-old person of non-Hispanic white, non-Hispanic black, Hispanic, or Asian race or ethnicity...
May 17, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29775617/preoperative-lymphocyte-to-monocyte-ratio-predicts-breast-cancer-outcome-a-meta-analysis
#7
REVIEW
Ru-Jin Hu, Qin Liu, Jian-Ying Ma, Jing Zhou, Gang Liu
AIM: To assess the prognostic value of the preoperative lymphocyte-to-monocyte ratio (LMR) in patients with breast cancer (BC). METHODS: Relevant studies were systematically retrieved from the online Cochrane, MEDLINE, EMBASE and CNKI databases published until February 2018. The end points were overall survival (OS), disease-free survival (DFS), and clinicopathological parameters. Meta-analysis was performed using hazard ratios (HRs) or odds ratios (ORs) and their 95% confidence intervals (CIs) as effect measures...
May 17, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29772933/the-approach-to-solitary-fibrous-tumors-are-clinicopathological-features-and-nomograms-accurate-in-the-prediction-of-prognosis
#8
Deanna Wan Jie Ng, Grace Hwei Ching Tan, Joel Jia Yi Soon, David Yue Zhao, Nicholas Brian Shannon, Sathiyamoorthy Selvarajan, Khee Chee Soo, Melissa Ching Ching Teo
INTRODUCTION: Currently, factors such as size, mitotic rate, and degree of necrosis have been shown to influence survival in patients with solitary fibrous tumors (SFTs); however, there remains no consensus regarding the associations between tumor characteristics and the malignant nature of these tumors. The aim of this article was to identify factors that would help in prognosticating SFTs and to validate the MD Anderson Cancer Center (MDACC) SFT nomogram in the largest known series of SFTs treated in an Asian population...
May 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29767739/efficacy-immunogenicity-and-safety-of-a-9-valent-human-papillomavirus-vaccine-subgroup-analysis-of-participants-from-asian-countries
#9
S M Garland, P Pitisuttithum, H Y S Ngan, C-H Cho, C-Y Lee, C-A Chen, Y C Yang, T-Y Chu, N-F Twu, R Samakoses, Y Takeuchi, T H Cheung, S C Kim, L-M Huang, B-G Kim, Y-T Kim, K-H Kim, Y-S Song, S Lalwani, J-H Kang, M Sakamoto, H-S Ryu, N Bhatla, H Yoshikawa, M C Ellison, S R Han, E Moeller, S Murata, M Ritter, M Sawata, C Shields, A Walia, G Perez, A Luxembourg
Background: A 9-valent human papillomavirus-6/11/16/18/31/33/45/52/58 (9vHPV) vaccine extends coverage to 5 next most common oncogenic types (31/33/45/52/58) in cervical cancer versus quadrivalent HPV (qHPV) vaccine. We describe efficacy, immunogenicity, and safety in Asian participants (India, Hong Kong, South Korea, Japan, Taiwan, and Thailand) from 2 international studies: a randomized, double-blinded, qHPV vaccine-controlled efficacy study (young women aged 16-26 years; NCT00543543; Study 001); and an immunogenicity study (girls and boys aged 9-15 years; NCT00943722; Study 002)...
May 15, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29766934/spectrum-of-metastatic-neoplasms-of-the-brain-a-clinicopathological-study-in-a-tertiary-care-cancer-centre
#10
Smrita Singh, Usha Amirtham, Chennagiri S Premalata, Kuntegowdanahalli C Lakshmaiah, Lokesh Viswanath, Rekha V Kumar
Background: While brain metastases (BM) are the most common causes of neurologic disorders in patients with known systemic malignancies, they can often be the initial manifestations of an undetected primary elsewhere. BM are major causes of morbidity and mortality in cancer patients. Aims: We describe a mixed population (data from both retrospective and prospective collection) having a BM from a solid tumor. We report the percentage distribution of the most frequent types of BM, confirming the data published in the literature...
May 2018: Neurology India
https://www.readbyqxmd.com/read/29766659/prognosis-of-patients-with-hepatocellular-carcinoma-treated-with-sorafenib-a-comparison-of-five-models-in-a-large-canadian-database
#11
Haider H Samawi, Hao-Wen Sim, Kelvin K Chan, Mohammad A Alghamdi, Richard M Lee-Ying, Jennifer J Knox, Parneet Gill, Adriana Romagnino, Eugene Batuyong, Yoo-Joung Ko, Janine M Davies, Howard J Lim, Winson Y Cheung, Vincent C Tam
Several systems (tumor-node-metastasis [TNM], Barcelona Clinic Liver Cancer [BCLC], Okuda, Cancer of the Liver Italian Program [CLIP], and albumin-bilirubin grade [ALBI]) were developed to estimate the prognosis of patients with hepatocellular carcinoma (HCC) mostly prior to the prevalent use of sorafenib. We aimed to compare the prognostic and discriminatory power of these models in predicting survival for HCC patients treated with sorafenib and to identify independent prognostic factors for survival in this population...
May 15, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29764334/obesity-physical-activity-and-dietary-behaviors-in-an-ethnically-diverse-sample-of-cancer-survivors-with-early-onset-disease
#12
Beth A Glenn, Ann S Hamilton, Narissa J Nonzee, Annette E Maxwell, Catherine M Crespi, A Blythe Ryerson, L Cindy Chang, Dennis Deapen, Roshan Bastani
PURPOSE: To assess weight status, physical activity, and dietary behaviors in an ethnically-diverse sample of breast and colorectal cancer survivors with early onset disease (≤ 50 years). METHODS: Breast and colorectal cancer survivors, diagnosed between 1999 and 2009 with early-stage cancer diagnosed by 50 years of age, were identified through a population-based cancer registry and surveyed. Descriptive and regression analyses were conducted to characterize the sample and identify correlates of lifestyle behaviors...
May 15, 2018: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/29761671/risk-factors-for-complications-of-total-subtotal-gastrectomy-for-gastric-cancer-prospectively-collected-based-on-the-clavien-dindo-classification-system
#13
Yehonatan Nevo, Yuri Goldes, Liran Barda, Roy Nadler, Mordechai Gutman, Avinoam Nevler
BACKGROUND: Recent studies have analyzed risk factors associated with complications after gastric cancer surgery using the Clavien-Dindo classification (CD). However, they have been based on Asian population cohorts (Chinese, Japanese, Korean). OBJECTIVES: To prospectively analyze all post-gastrectomy complications according to severity using CD classification and identify postoperative risk factors and complications. METHODS: We analyzed all gastrectomies for gastric cancer performed 2009-2014...
May 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29758276/age-of-menarche-in-a-longitudinal-us-cohort
#14
Frank M Biro, Ashley Pajak, Mary S Wolff, Susan M Pinney, Gayle C Windham, Maida P Galvez, Louise C Greenspan, Larry H Kushi, Susan L Teitelbaum
STUDY OBJECTIVES: Menarche is a critical milestone in a woman's life, and historically has been determined through several approaches. The goals of this study were to: 1) determine age at menarche from multiple reports of parents and adolescent participants in a prospective study; 2) examine factors impacting age at menarche; and 3) determine correlates of menarche and pubertal tempo. DESIGN: Longitudinal observational study. SETTING: Three sites of the Breast Cancer and the Environment Research Program...
May 11, 2018: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29757872/pattern-of-care-health-care-disparities-and-their-impact-on-survival-outcomes-in-stage-ivb-cervical-cancer-a-nationwide-retrospective-cohort-study
#15
Randa J Jalloul, Shelly Sharma, Celestine S Tung, Barrett OʼDonnell, Michelle Ludwig
OBJECTIVE: Although locally advanced cervical cancer can be cured, patients with stage IVB disease have poor prognosis with limited treatment options. Our aim was to describe the pattern of care and analyze health disparity variables that may account for differences in treatment modalities and survival in this population. METHODS: The National Cancer Database was queried for patients diagnosed between 2004 and 2013 with metastatic squamous cell carcinoma or adenocarcinoma of the cervix...
May 4, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29753147/occupational-exposure-and-consequent-health-impairments-due-to-potential-incidental-nanoparticles-in-leather-tanneries-an-evidential-appraisal-of-south-asian-developing-countries
#16
REVIEW
Fiza Sarwar, Riffat Naseem Malik, Chung Wai Chow, Khan Alam
The incidental nanoparticles' (INPs) emission at work and the consequent health impairments is a burning issue of occupational toxicology. The present study is a thorough review of available literature marking an assortment of indicators on INPs generation at leather tanneries and measurable occupational ailments. The literature reported evidences unleash a similarity between the mechanisms of leather tannery induced health damages and toxico-kinetics of incidental nanoparticles in human body. The data on physico-chemical characterization of leather tannery surface dust presents presence of stressors like heavy metals, microbes, animal fur and fibers along with organic and inorganic chemicals...
May 9, 2018: Environment International
https://www.readbyqxmd.com/read/29753039/screening-for-gastric-cancer-with-magnetically-controlled-capsule-gastroscopy-in-asymptomatic-individuals
#17
An-Jing Zhao, Yang-Yang Qian, Hui Sun, Xi Hou, Jun Pan, Xiao Liu, Wei Zhou, Yi-Zhi Chen, Xi Jiang, Zhao-Shen Li, Zhuan Liao
BACKGROUND AND AIMS: Gastric cancer (GC) is the fourth most common cancer and the fourth leading cause of cancer death worldwide. In some Asian countries, screening esophagogastroduodenoscopy (EGD) has greatly improved the survival rate. However, patients' discomfort and the need for sedation may limit adherence to screening programs. Prior studies have shown good tolerance and good agreement of magnetically controlled capsule gastroscopy (MCCG) with EGD. This study was designed to assess the application of MCCG in GC detection in an asymptomatic population...
May 9, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29752341/-ercc1-rs11615-polymorphism-increases-susceptibility-to-breast-cancer-a-meta-analysis-of-4547-individuals
#18
Bingjie Li, Xiaoqing Shi, Yingying Yuan, Mengle Peng, Huifang Jin, Dongchun Qin
Excision repair cross-complementation group 1 (ERCC1), a DNA repair protein, is vital for maintaining genomic fidelity and integrity. Despite the fact that a mounting body of case-control studies has concentrated on investigating the association of the ERCC1 rs11615 polymorphism and breast cancer risk, there is still no consensus on it. We conducted the current meta-analysis of all eligible articles to reach a much more explicit conclusion on this ambiguous association. A total of seven studies involving 2354 breast cancer cases and 2193 controls were elaborately selected for this analysis from the Embase, EBSCO, Pubmed, WanFang and China National Knowledge Infrastructure (CNKI) databases...
May 11, 2018: Bioscience Reports
https://www.readbyqxmd.com/read/29750905/learning-needs-of-women-who-undergo-robotic-versus-open-gynecologic-surgery
#19
Gonul Kurt, Victoria W Loerzel, Robert B Hines, Krystal Tavasci, Sandra Galura, Sarfraz Ahmad, Robert W Holloway
OBJECTIVES: To compare the learning needs of women undergoing robotic versus open (laparotomy) gynecologic surgery for benign and cancerous conditions. DESIGN: Descriptive exploratory study. SETTING: A tertiary care hospital in Orlando, Florida. PARTICIPANTS: Women undergoing gynecologic surgery (N = 226; n = 71 laparotomy and n = 155 robotic). METHODS: All consenting procedures and data collection occurred in two study visits...
May 8, 2018: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/29750160/temporal-trends-of-common-female-malignances-on-breast-cervical-and-ovarian-cancer-mortality-in-japan-republic-of-korea-and-singapore-application-of-the-age-period-cohort-model
#20
Jinyao Wang, Haizhen Lv, Zhilin Xue, Lu Wang, Zhiqiang Bai
Background: Reproductive system cancer is an important cause of morbidity and mortality worldwide which threatens women's health and lives. Breast, cervical, and ovarian cancer have the higher incidence and mortality among a series of gynecology malignant tumor. We aimed to compare and assess the temporal trends of common female malignances on breast, cervical, and ovarian cancer mortality in developed regions of Asia including Japan, Republic of Korea, and Singapore and analyze the detached effects of chronological age, time period, and birth cohort by age-period-cohort (APC) analysis...
2018: BioMed Research International
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