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https://www.readbyqxmd.com/read/29689472/autonomic-dysreflexia-following-acute-myelitis-due-to-neuromyelitis-optica
#1
Julio C Furlan
BACKGROUND: Cardiovascular autonomic dysfunction is a relatively common secondary complication of tetraplegia. In addition to low baseline arterial blood pressure, tetraplegics can develop sudden-onset hypertensive episodes associated with a variety of symptoms and signs (so-called autonomic dysreflexia). Unfortunately, this potentially life-threatening medical entity is often overlooked and mismanaged. With this, a case of typical presentation of autonomic dysreflexia in an individual with acute severe cervical spinal cord impairment due to neuromyelitis optica (NMO) is reported and discussed...
April 16, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29688843/cost-of-medical-care-of-patients-with-advanced-serious-illness-in-singapore-compass-prospective-cohort-study-protocol
#2
Irene Teo, Ratna Singh, Chetna Malhotra, Semra Ozdemir, Rebecca A Dent, Nesaretnam Barr Kumarakulasinghe, Wee Lee Yeo, Yin Bun Cheung, Rahul Malhotra, Ravindran Kanesvaran, Alethea Chung Pheng Yee, Noreen Chan, Huei Yaw Wu, Soh Mun Chin, Hum Yin Mei Allyn, Grace Meijuan Yang, Patricia Soek Hui Neo, Nivedita V Nadkarni, Richard Harding, Eric A Finkelstein
BACKGROUND: Advanced cancer significantly impacts quality of life of patients and families as they cope with symptom burden, treatment decision-making, uncertainty and costs of treatment. In Singapore, information about the experiences of advanced cancer patients and families and the financial cost they incur for end-of-life care is lacking. Understanding of this information is needed to inform practice and policy to ensure continuity and affordability of care at the end of life. The primary objectives of the Cost of Medical Care of Patients with Advanced Serious Illness in Singapore (COMPASS) cohort study are to describe changes in quality of life and to quantify healthcare utilization and costs of patients with advanced cancer at the end of life...
April 23, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29688754/aripiprazole-for-irritability-in-asian-children-and-adolescents-with-autistic-disorder-a-12-week-multinational-multicenter-prospective-open-label-study
#3
Hyo-Won Kim, Eun-Jin Park, Ji-Hoon Kim, Vitharon Boon-Yasidhi, Jariya Tarugsa, Alexis Reyes, Stella Manalo, Yoo-Sook Joung
OBJECTIVES: We investigated the effectiveness and tolerability of aripiprazole in the treatment of irritability in Asian children and adolescents (6-17 years) with autistic disorder in a 12-week, multinational, multicenter, open-label study. METHODS: Sixty-seven subjects (10.0 ± 3.1 years old, 52 boys) were enrolled and treated with flexibly dosed aripiprazole for 12 weeks (mean dose, 5.1 ± 2.5 mg; range 2-15 mg). RESULTS: Aripiprazole significantly reduced the mean caregiver-rated scores for the Irritability, Lethargy/Social Withdrawal, Stereotypy, Hyperactivity, and Inappropriate Speech subscales of the Aberrant Behavior Checklist from baseline to week 12 (p < 0...
April 24, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29682835/longitudinal-examination-of-family-efficacy-following-pediatric-stem-cell-transplant
#4
Rachel Tillery, Naomi E Joffe, Constance A Mara, Stella M Davies, Ahna L H Pai
OBJECTIVE: Pediatric stem cell transplant (pSCT) is emotionally demanding for families. Yet, we know little of how the family unit responds to the adversity of pSCT within the first year after transplant. Family efficacy, an indicator of family resilience, is linked to positive parent, child, and family adjustment. Better understanding the factors that promote family efficacy during this difficult time could inform modifiable intervention targets and improve child and parent adjustment...
April 23, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29666801/current-therapeutic-landscape-for-advanced-gastroesophageal-cancers
#5
REVIEW
Anthony Lopez, Kazuto Harada, Dilsa Mizrak Kaya, Jaffer A Ajani
Treatment of advanced gastroesophageal cancers remains challenging for clinicians, patients, and caregivers alike. Despite considerable research, the therapeutic armamentarium is restricted and hardly personalized. In the first-line setting, trastuzumab with a fluoropyrimidine and platinum agent is the standard-of-care in patients with HER2-positive tumor. For the others, a platinum-based doublet (preferably with oxaliplatin) is recommended. Three-drug cytotoxic regimens should be reserved for exceptional cases where patients have good performance status...
February 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29572220/caregiver-experiences-of-racism-and-child-healthcare-utilisation-cross-sectional-analysis-from-new-zealand
#6
Sarah-Jane Paine, Ricci Harris, James Stanley, Donna Cormack
OBJECTIVES: Children's exposure to racism via caregiver experience (vicarious racism) is associated with poorer health and development. However, the relationship with child healthcare utilisation is unknown. We aimed to investigate (1) the prevalence of vicarious racism by child ethnicity; (2) the association between caregiver experiences of racism and child healthcare utilisation; and (3) the contribution of caregiver socioeconomic position and psychological distress to this association...
March 23, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29554838/caregiver-reported-sleep-disturbances-are-associated-with-behavioral-and-psychological-symptoms-in-an-asian-elderly-cohort-with-cognitive-impairment-no-dementia
#7
Xin Xu, Cheuk Ni Kan, Tien Yin Wong, Ching-Yu Cheng, M Kamran Ikram, Christopher Li-Hsian Chen, Narayanaswamy Venketasubramanian
OBJECTIVE: Sleep disturbances were found to be associated with more behavioral and psychological symptoms (BPS) in early patients with Alzheimer's disease (AD). However, data on preclinical stages of dementia are lacking. Hence, the present study sought to investigate the association between sleep disturbances and BPS in dementia-free elderly with varying severity of cognitive impairment in an Asian sample. METHODS: Community-living elderly were recruited and administered a comprehensive cognitive battery (vascular dementia battery [VDB]) and the Neuropsychiatric Inventory to assess symptoms of sleep disturbances and BPS...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/29554461/surgical-care-for-school-aged-youth-with-cleft-results-from-a-multicenter-prospective-observational-study
#8
Richard Ryan Ruff, Canice E Crerand, Lacey Sischo, Alexandre Peshansky, David B Sarwer, Richard E Kirschner, Hillary L Broder
OBJECTIVE: To explore factors related to completion of surgery recommendations among children with cleft lip and palate (CLP) or cleft palate only (CPO). DESIGN: Multicenter prospective longitudinal cohort study (2009-2015). SETTING: Six cleft centers in the United States. PATIENTS/PARTICIPANTS: A diverse sample of 1186 youth aged 7.5 to 18.5 years with CLP or CPO and a caregiver. RESULTS: Data were collected from child-caregiver dyads at baseline and up to 3 follow-up visits...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29512485/frequent-community-use-of-antibiotics-among-a-low-economic-status-population-in-manila-the-philippines-a-prospective-assessment-using-a-urine-antibiotic-bioassay
#9
Nobuo Saito, Noriko Takamura, Grace P Retuerma, Carina H Frayco, Paul S Solano, Cherlyn D Ubas, Arianne V Lintag, Maricel R Ribo, Rontgene M Solante, Alexis Q Dimapilis, Elizabeth O Telan, Winston S Go, Motoi Suzuki, Koya Ariyoshi, Christopher M Parry
The widespread unregulated use of antibiotics without medical consultation contributes to the burden of antibiotic resistance in Southeast Asian countries. This study investigated antibiotic use before hospital consultation. In a prospective observational study from February 2, 2015, to July 2, 2015, we enrolled febrile patients attending the emergency room in San Lazaro Hospital, Manila, the Philippines. A urine sample was collected and a bioassay was used to detect antibiotic activity in urine using Bacillus stearothermophilus (ATCC7953), Escherichia coli (ATCC25922), and Streptococcus pyogenes (ATCC19615)...
May 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29376188/fall-concern-about-older-persons-shifts-to-carers-as-changing-health-policy-focuses-on-family-home-based-care
#10
Seng Giap Marcus Ang, Anthony Paul O'Brien, Amanda Wilson
With the Singaporean population ageing at an exponential rate, home carers are increasingly becoming essential partners in fall prevention and care delivery for older persons living at home and in the community. Singapore, like other Asian countries, regards the family as the main support structure for the older person, and national policies have been implemented to support this cultural expectation. Family carers experience similar concerns as older persons with regard to fall risk, and identifying and addressing these concerns can potentially lower fall risk and improve fall prevention for older persons...
January 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29241090/attachment-style-and-filial-obligation-in-the-burden-of-caregivers-of-dementia-patients
#11
Juwon Lee, Bo Kyung Sohn, Hyunjoo Lee, Su Jeong Seong, Soowon Park, Jun-Young Lee
Insecure attachment styles have been known to predict greater burden in caregivers of dementia patients. However, it has not been tested how filial obligation, which refers to one's sense of duty on helping elderly parents and is especially pronounced in Asian cultures, is involved in that relationship. We sought to identify whether the association between attachment style and caregiver burden differs according to the degree of filial obligation in caregivers of dementia patients. To assess filial obligation in Korean participants, a Korean filial obligation measure was developed...
March 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29219936/end-of-life-care-discussion-for-residents-with-dementia-in-long-term-care-facilities
#12
Hsiu-Li Huang, Li-Chueh Weng, WeWen-Yu Hu, Yea-Ing Lotus Shyu, Wen-Pin Yu, Kang-Hua Chen
BACKGROUND: Healthcare professionals play an important role in end-of-life care decisions. Although the factors affecting end-of-life care in long-term care facilities have been well studied in Western contexts, few studies have examined factors affecting end-of-life care discussions for residents with dementia among multidisciplinary professionals in Asian or Taiwanese contexts. PURPOSE: The aim of this study was to explore the factors related to the end-of-life care discussions of registered nurses, social workers, and physicians with residents with dementia and their families...
December 6, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29202863/a-novel-family-dignity-intervention-fdi-for-enhancing-and-informing-holistic-palliative-care-in-asia-study-protocol-for-a-randomized-controlled-trial
#13
Andy Hau Yan Ho, Josip Car, Moon-Ho Ringo Ho, Geraldine Tan-Ho, Ping Ying Choo, Paul Victor Patinadan, Poh Heng Chong, Wah Ying Ong, Gilbert Fan, Yee Pin Tan, Robert A Neimeyer, Harvey M Chochinov
BACKGROUND: The lack of a holistic approach to palliative care can lead to a fractured sense of dignity at the end of life, resulting in depression, hopelessness, feelings of being a burden to others, and the loss of the will to live among terminally ill patients. Building on the clinical foundation of Dignity Therapy, together with the empirical understanding of dignity-related concerns of Asian families facing terminal illness, a novel Family Dignity Intervention (FDI) has been developed for Asian palliative care...
December 4, 2017: Trials
https://www.readbyqxmd.com/read/29181245/usages-of-computers-and-smartphones-to-develop-dementia-care-education-program-for-asian-american-family-caregivers
#14
Jung-Ah Lee, Hannah Nguyen, Joan Park, Linh Tran, Trang Nguyen, Yen Huynh
Objectives: Families of ethnic minority persons with dementia often seek help at later stages of the disease. Little is known about the effectiveness of various methods in supporting ethnic minority dementia patients' caregivers. The objective of the study was to identify smartphone and computer usage among family caregivers of dementia patients (i.e., Korean and Vietnamese Americans) to develop dementia-care education programs for them. Methods: Participants were asked various questions related to their computer or smartphone usage in conjunction with needs-assessment interviews...
October 2017: Healthcare Informatics Research
https://www.readbyqxmd.com/read/28993888/oncologists-responses-to-patient-and-caregiver-negative-emotions-and-patient-perception-of-quality-of-communication-results-from-a-multi-ethnic-asian-setting
#15
Chetna Malhotra, Ravindran Kanesvaran, Lalit Krishna, Ling Xiang, Nesaretnam Barr Kumarakulasinghe, Sing-Huang Tan, James A Tulsky, Kathryn I Pollak
PURPOSE: Patients with advanced cancer and their caregivers experience many negative emotions. Empathic responses from oncologists can help alleviate their distress. We aimed to assess expressions of negative emotions among patients with advanced cancer and their caregivers and oncologists' empathic responses during consultations in an Asian setting. We also assessed the association between oncologists' expression of empathy and patients' and caregivers' perception of communication quality...
March 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28980423/asian-americans-concerns-and-plans-about-alzheimer-s-disease-the-role-of-exposure-literacy-and-cultural-beliefs
#16
Yuri Jang, Hyunwoo Yoon, Nan Sook Park, Min-Kyoung Rhee, David A Chiriboga
Responding to the increase of the Asian American population and the growing imperative to address issues on Alzheimer's disease (AD) in diverse populations, this study examined Asian Americans' concerns about AD (both concerns about one's own development of AD and about becoming an AD caregiver) and plans for AD. Focus was given on exploring the role of AD exposure, AD literacy and cultural beliefs about AD in predicting AD-related concerns and plans. Using data from 2,609 participants in the 2015 Asian American Quality of Life survey (aged 18-98), logistic regression models of three outcome measures (concerns about one's own development of AD, concerns about becoming an AD caregiver and plans about AD) were estimated...
March 2018: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28960806/regional-evidence-and-international-recommendations-to-guide-lipid-management-in-asian-patients-with-type-2-diabetes-with-special-reference-to-renal-dysfunction
#17
REVIEW
Titus Wl Lau, Kevin E K Tan, Jason C J Choo, Tsun-Gun Ng, Subramaniam Tavintharan, Juliana C N Chan
The anticipated increase in the prevalence and incidence of type 2 diabetes in Asia, and its associated cardiovascular-renal complications, will place a significant burden on patients, caregivers, and society. Despite the proven effectiveness of lipid management in reducing these complications, there are major treatment gaps, especially in Asian patients with young-onset diabetes and chronic kidney disease (CKD). Recent international guidelines recommended the adoption of absolute risk estimation of atherosclerosis and cardiovascular disease to guide treatment intensity...
March 2018: Journal of Diabetes
https://www.readbyqxmd.com/read/28860777/efficacy-and-safety-of-paliperidone-palmitate-three-monthly-formulation-in-east-asian-patients-with-schizophrenia-subgroup-analysis-of-a-global-randomized-double-blind-phase-iii-noninferiority-study
#18
Adam J Savitz, Haiyan Xu, Srihari Gopal, Isaac Nuamah, Paulien Ravenstijn, David Hough, Maju Mathews, Yu Feng, Lu Yu, Masayoshi Takahashi, Dennis Liu, Gang Wang, Jin-Sang Yoon, Jiahn-Jyh Chen
OBJECTIVE: To demonstrate the efficacy and safety of paliperidone palmitate three-monthly (PP3M) formulation in an East Asian population with schizophrenia by subgroup analysis of a double-blind (DB), multicenter, noninferiority study. PATIENTS AND METHODS: Of 1,429 patients who entered the open-label (OL) phase, 510 were East Asian (China: 296 [58%], Japan: 175 [34%], South Korea: 19 [4%] and Taiwan: 20 [4%]). In the 17-week OL phase, patients received paliperidone palmitate once-monthly (PP1M) formulation on day 1 (150 mg eq...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28826704/the-application-of-a-three-dimensional-printed-product-to-fill-the-space-after-organ-removal
#19
Jui-Yu Weng, Che-Chuna Wang, Pei-Jar Chen, Sher-Wei Lim, Jinn-Rung Kuo
BACKGROUND: Maintaining body integrity, especially in Asian societies, is an independent predictor of organ donation. CASE DESCRIPTION: Herein, we report the case of an 18-year-old man who suffered a traumatic brain injury with ensuing brain death caused by a car accident. According to the family's wishes, we used a 3-dimensional printer to create simulated heart, kidneys, and liver to fill the spaces after the patient's organs were removed. This is the first case report to introduce this new clinical application of 3-dimensional printed products during transplantation surgery...
November 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28805434/the-differential-influences-of-parenting-and-child-narrative-coherence-on-the-development-of-emotion-recognition
#20
Sara R Berzenski, Tuppett M Yates
The ability to recognize and label emotions serves as a building block by which children make sense of the world and learn how to interact with social partners. However, the timing and salience of influences on emotion recognition development are not fully understood. Path analyses evaluated the contributions of parenting and child narrative coherence to the development of emotion recognition across ages 4 through 8 in a diverse (50% female; 46% Hispanic, 18.4% Black, 11.2% White, .4% Asian, 24.0% multiracial) longitudinally followed sample of 250 caregiver-child dyads...
October 2017: Developmental Psychology
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