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https://www.readbyqxmd.com/read/28854874/recognition-and-treatment-of-severe-sepsis-in-the-emergency-department-retrospective-study-in-two-french-teaching-hospitals
#1
Philippe Le Conte, Séverin Thibergien, Jean Batiste Obellianne, Emmanuel Montassier, Gilles Potel, Pierre Marie Roy, Eric Batard
BACKGROUND: Sepsis management in the Emergency Department remains a daily challenge. The Surviving Sepsis Campaign (SSC) has released three-hour bundle. The implementation of these bundles in European Emergency Departments remains poorly described. The main objective was to assess the compliance with the Severe Sepsis Campaign 3-h bundle (blood culture, lactate dosage, first dose of antibiotics and 30 ml/kg fluid challenge). Secondary objectives were the analysis of the delay of severe sepsis recognition and description of the population...
August 30, 2017: BMC Emergency Medicine
https://www.readbyqxmd.com/read/28792287/the-association-of-generalized-anxiety-disorder-and-somatic-symptoms-with-frequent-attendance-to-health-care-services-a-cross-sectional-study-from-the-northern-finland-birth-cohort-1966
#2
Tero S Kujanpää, Jari Jokelainen, Juha P Auvinen, Markku J Timonen
Objective Generalized anxiety disorder is associated with higher rate of physical comorbities, unexplained symptoms, and health care utilization. However, the role of somatic symptoms in determining health care utilization is unclear. The present study aims to assess the association of frequent attendance of health care services between generalized anxiety disorder symptoms and somatic symptoms. Method This study was conducted cross-sectionally using the material of the 46-year follow-up survey of the Northern Finland Birth Cohort 1966...
March 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28714619/-intermittent-claudication-and-critical-limb-ischemia-from-diagnosis-to-management
#3
Pierre-Henri Morère
In case of atheromatous disease, the practitioner should be part of a multidisciplinary decision due to the associated comorbities. The angiologic assessment is of paramount importance in the diagnosis of peripheral artery disease even when the diagnosis seems clear. Unfortunately the patient is very often straightforward sent to radiological investigations who are faster. In all stages of peripheral artery disease, the medical treatment should be tried first except in case of critical limb ischemia where an invasive approach must be performed for revascularisation...
March 1, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28637084/integra-dermal-regeneration-template-for-neck-reconstruction-in-a-previously-irradiated-patient
#4
Nikoleta Skalidi, Jenny Montgomery
1 Integra artificial dermal regeneration template can be an alternate product for neck reconstruction in previously irradiated patients with poor performance status. 2 Integra can be succefully used as one stage procedure providing good aesthetic outcomes. 3 One stage procedure of Integra minimizes the surgical time and donor site comorbity from harvesting skin grafts. This article is protected by copyright. All rights reserved.
June 21, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28622335/psychotic-symptoms-in-older-people-without-dementia-from-a-brazilian-community-based-sample-a-seven-years-follow-up
#5
Walter Barbalho Soares, Eriton Barros Dos Santos, Cássio Machado de Campos Bottino, Helio Elkis
BACKGROUND: Studies of the incidence of psychotic symptoms in elderly people at risk of dementia are scarce. This is a seven year follow up study aiming to determine the incidence of psychotic symptoms and their correlation with other clinical aspects, in particular the rate of development of cognitive impairment. METHODS: Cohort study of a community-based sample of elderly subjects. At study entry in 2004, the sample was composed of 1,125 individuals aged 60 years and older...
2017: PloS One
https://www.readbyqxmd.com/read/28469275/prognostic-value-of-impaired-estimated-glomerular-filtration-rate-in-intravesical-bcg-treated-non-muscle-invasive-bladder-cancer-patients
#6
Bum Sik Tae, Jung Kwon Kim, Minyong Kang, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, Ja Hyeon Ku
To evaluate the influence of patient-associated parameters and comorbities, with a special focus on renal function after intravesical adjuvant bacillus Calmette-Gue´rin (BCG) immunotherapy in patients with non-muscle-invasive bladder cancer (NMIBC). We retrospectively reviewed the medical records of patients treated from October, 1991 to December, 2013 at Seoul National University who were diagnosed with NMIBC and treated with intravesical BCG. A total of 344 patients who were diagnosed with NMIBC and treated with intravesical BCG were enrolled in this study...
May 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28387104/-anemia-in-patients-with-severe-chronic-obstructive-pulmonary-disease-a-comorbity-more-common-than-previously-thought
#7
M Pirotte, J Guiot, Y Beguin, R Louis
Chronic Obstructive Pulmonary Disease (COPD) is traditionally associated with polycythemia which results from chronic hypoxemia. Nevertheless, recent studies have shown that anemia may be more frequent than expected in patients with COPD. In this retrospective study, we investigated the prevalence of hemoglobin disorders in a cohort of 100 patients with stable, moderate to severe COPD (II to IV GOLD classification). We identified 31 % patients with anemia while only 15 % had polycythemia. Anemia was more frequent in male patients...
November 2016: Revue Médicale de Liège
https://www.readbyqxmd.com/read/27970766/cost-analysis-of-comorbities-evidence-from-a-hiv-patients-cohort
#8
E Foglia, L Ferrario, E Garagiola, G Rizzardini, P Meraviglia, C Atzori, D Croce
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27905692/remote-pre-procedural-ischemic-stroke-as-the-greatest-risk-in-carotid%C3%A2-stenting%C3%A2-associated-stroke-and-death-a-single-center-s-experience
#9
Mária Rašiová, Ľubomír Špak, Ľudmila Farkašová, Štefan Pataky, Martin Koščo, Marek Hudák, Matej Moščovič, Norbert Leško
BACKGROUND: The goal of carotid artery stenting (CAS) is to decrease the stroke risk in patients with carotid stenosis. This procedure carries an immediate risk of stroke and death and many patients do not benefit from it, especially asymptomatic patients. It is crucial to accurately select the patients who would benefit from carotid procedure, and to rule out those for whom the procedure might be hazardous. Remote ischemic stroke is a known risk factor for stroke recurrence during surgery...
August 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/27539492/susceptibility-etching-on-mri-in-patients-with-microangiopathy
#10
Jennifer Chang, Keerthi Arani, Sheena Chew, Matthew P Frosch, R Gilberto Gonzalez, Noor Maza, Javier M Romero
BACKGROUND: We detected a novel imaging sign, which consists of a specific imaging pattern of diffuse susceptibility effect, delineating the cortical-subcortical junction on high-resolution susceptibility-weighted images (SWIs). We describe magnetic resonance imaging findings in 10 patients with "susceptibility etching" and possible association with their abnormal coagulation profile. MATERIALS/METHODS: A retrospective case series study with a search for cases that demonstrated susceptibility effect at the cortical-subcortical junction on SWI sequences was performed...
January 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/27495143/comorbidities-treatment-and-outcome-in-severe-anogenital-inverse-acne-hidradenitis-suppurativa-a-15-year-single-center-report
#11
Uwe Wollina, Dana Langner, Birgit Heinig, Andreas Nowak
BACKGROUND: Acne inversa (hidradentitis suppurativa; AI) is a severe chronic relapsing inflammatory skin disease of unknown cause. Anogenital AI has the strongest negative impact on quality of life and causes great disability. OBJECTIVES: We analyzed patients, comorbities, outcome of extensive surgery, and possible adverse effects. PATIENTS AND METHODS: We included patients from January 2000 to March 2015 with anogenital AI Hurley grade III...
January 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/27285279/one-year-mortality-in-copd-after-an-exacerbation-the-effect-of-physical-activity-changes-during-the-event
#12
Cristóbal Esteban, Susana Garcia-Gutierrez, Maria J Legarreta, Ane Anton-Ladislao, Nerea Gonzalez, Iratxe Lafuente, Nerea Fernandez de Larrea, Silvia Vidal, Marisa Bare, José M Quintana, Iryss -Copd Group
Mortality is one of the most important outcomes in patients with chronic obstructive pulmonary disease (COPD). Different predictors have been associated with mortality, including the patient's level of physical activity (PA). The objective of this work was to establish the relationship between changes in PA during a moderate-to-severe COPD exacerbation (eCOPD) and 1-year mortality after the index event. This was a prospective observational cohort study with recruitment of 2,484 patients with an eCOPD attending the emergency department (ED) of 16 participating hospitals...
December 2016: COPD
https://www.readbyqxmd.com/read/27262141/update-on-active-surveillance-for-clinical-t1-renal-tumors
#13
Gregory A Joice, Phillip M Pierorazio, Mohamad E Allaf
PURPOSE OF REVIEW: The purpose is to discuss current data on the utilization and outcomes of active surveillance for T1a renal masses. Specifically, to address which patients are optimal for active surveillance and how their outcomes differ from those undergoing immediate treatment. RECENT FINDINGS: Although nephron sparing surgery is the standard of care for small renal masses (SRMs), active surveillance is becoming a more popular intervention given the results of prospective studies revealing active surveillance to be safe and have excellent cancer-specific survival with intermediate follow-up...
September 2016: Current Opinion in Urology
https://www.readbyqxmd.com/read/27245505/does-central-sensitization-help-explain-idiopathic-overactive-bladder
#14
REVIEW
W Stuart Reynolds, Roger Dmochowski, Alan Wein, Stephen Bruehl
The pathophysiological mechanisms underlying overactive bladder syndrome (OAB) can include dysfunction of sensory pathways of the peripheral and central nervous systems, resulting in bladder hypersensitivity. Central sensitization describes an induced state of spinal hypersensitivity that is associated with a variety of chronic pain disorders that share many attributes with OAB, albeit without the presence of pain. As such, the concept of central sensitization might be relevant to understanding the mechanisms and clinical manifestations of OAB syndrome...
August 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27005725/time-to-consultation-liaison-psychiatry-service-referral-as-a-predictor-of-length-of-stay
#15
Sanjeev Sockalingam, Ahmad Alzahrani, Christopher Meaney, Rima Styra, Adrienne Tan, Raed Hawa, Susan E Abbey
OBJECTIVES: The aim of this study was to determine the relationship between the time to referral (TTR) to psychiatric consultation and the length of stay (LOS) after adjusting for medical comorbity. METHODS: Using a naturalistic study design, we collected and analyzed inpatient consultation-liaison psychiatry service data over a 12-month period from 2 Canadian hospital sites. Data collected included demographic characteristics, referral characteristics, Charlson Comorbidity Index to measure medical comorbidity severity, psychiatric diagnoses, type of psychiatric intervention, and time variables, namely TTR and LOS...
May 2016: Psychosomatics
https://www.readbyqxmd.com/read/26890327/cost-averted-with-timely-fecal-microbiota-transplantation-in-the-management-of-recurrent-clostridium-difficile-infection-in-alberta-canada
#16
Arianna Waye, Kerry Atkins, Dina Kao
BACKGROUND: Fecal microbiota transplantation (FMT) is highly effective in treating recurrent Clostridium difficile infection (RCDI). However, the ideal timing for offering FMT remains to be determined. Furthermore, the direct medical costs averted with timely FMT have not been examined. METHODS: A retrospective review of the Edmonton FMT program database included patients who received FMT for RCDI (October 2012 to September 2014). They were divided into 2 groups: those who received FMT after 2 recurrences (the timely FMT group) and those who received FMT after at least 3 recurrences (the delayed FMT group)...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/26829958/assessment-of-possible-drug-interactions-in-patients-with-psoriasis-and-associated-comorbid-medical-conditions-an-observational-study
#17
Reena Sherin, Padmaja Udaykumar
BACKGROUND: Associated co-morbidities with psoriasis are treated with concomitant medications apart from the antipsoriatic therapy and the resulting Drug-Drug Interactions (DDI) may affect therapeutic outcome. OBJECTIVE: To assess the DDI in psoriatic patients with co-morbidities. METHOD: In this prospective observational analysis, 150 prescriptions of psoriatic patients, receiving two or more drugs were analysed using drug interaction checker software...
2016: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/26467416/the-management-and-outcomes-of-pharmacological-treatments-for-tinnitus
#18
REVIEW
Devon Beebe Palumbo, Kathleen Joos, Dirk De Ridder, Sven Vanneste
Tinnitus, a phantom sensation experienced by people around the world, currently is endured without a known cure. Some find the condition tolerable, while others are tortured on a daily basis from the incessant phantom noises. For those who seek treatment, oftentimes, they have a comorbid condition (e.g., depression, anxiety, insomnia), which is treated pharmaceutically. These products aim to reduce the comorbities associated with tinnitus thereby minimizing the overall burden present. Because of the phantom nature of tinnitus, it is often compared to neurologic pain...
2015: Current Neuropharmacology
https://www.readbyqxmd.com/read/26027433/primary-treatment-options-for-high-risk-medically-inoperable-early-stage-nsclc-patients
#19
REVIEW
Guy C Jones, Jason D Kehrer, Jenna Kahn, Bobby N Koneru, Ram Narayan, Tarita O Thomas, Kevin Camphausen, Minesh P Mehta, Aradhana Kaushal
Lung cancer is among the most common cancers worldwide and is the leading cause of cancer death in both men and women. For patients with early stage (American Joint Committee on Cancer T1-2, N0) non-small-cell lung cancer, the current standard of care is lobectomy with systematic lymph node evaluation. Unfortunately, patients with lung cancer often have medical comorbities, which may preclude the option of surgical resection. In such cases, a number of minimally invasive to noninvasive treatment options have gained popularity in the treatment of these high-risk patients...
November 2015: Clinical Lung Cancer
https://www.readbyqxmd.com/read/26019037/comorbidities-have-a-limited-impact-on-post-transplant-survival-in-carefully-selected-cirrhotic-patients-a-population-based-cohort-study
#20
Filipe S Cardoso, Sean M Bagshaw, Juan G Abraldes, Norman M Kneteman, Glenda Meeberg, Pedro Fidalgo, Constantine J Karvellas
BACKGROUND: Improving estimation of long-term survival of patients with end-stage liver disease after orthotopic liver transplantation (OLT) would optimize decisions on eligibility for transplant. We aimed to externally validate previously derived Charlson Comorbity Index for OLT (CCI-OLT); subsequently, we developed a new model to predict 5-year mortality after transplant. MATERIAL AND METHODS: This single center retrospective cohort study included 524 consecutive adult cirrhotic patients who underwent OLT in 2002-2012...
July 2015: Annals of Hepatology
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