keyword
MENU ▼
Read by QxMD icon Read
search

Risk aversion

keyword
https://www.readbyqxmd.com/read/29223043/affect-toward-the-self-and-self-injury-stimuli-as-potential-risk-factors-for-nonsuicidal-self-injury
#1
Kathryn R Fox, Jessica D Ribeiro, Evan M Kleiman, Jill M Hooley, Matthew K Nock, Joseph C Franklin
Few risk factors for nonsuicidal self-injury (NSSI) have been identified. This study investigated diminished aversion toward self-injury (i.e., NSSI, suicide/death stimuli) and self-criticism as unique NSSI risk factors. After terminating a treatment study, 154 adults with a recent and frequent NSSI history completed self-report and computer-based measures of psychopathology, implicit and explicit self-criticism, and implicit aversion to NSSI and suicide/death. Participants were then contacted 4 weeks later to test factors predicting NSSI frequency over this follow-up period...
December 1, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29211715/alcohol-abuse-drug-disulfiram-targets-cancer-via-p97-segregase-adaptor-npl4
#2
Zdenek Skrott, Martin Mistrik, Klaus Kaae Andersen, Søren Friis, Dusana Majera, Jan Gursky, Tomas Ozdian, Jirina Bartkova, Zsofia Turi, Pavel Moudry, Marianne Kraus, Martina Michalova, Jana Vaclavkova, Petr Dzubak, Ivo Vrobel, Pavla Pouckova, Jindrich Sedlacek, Andrea Miklovicova, Anne Kutt, Jing Li, Jana Mattova, Christoph Driessen, Q Ping Dou, Jørgen Olsen, Marian Hajduch, Boris Cvek, Raymond J Deshaies, Jiri Bartek
Cancer incidence is rising and this global challenge is further exacerbated by tumour resistance to available medicines. A promising approach to meet the need for improved cancer treatment is drug repurposing. Here we highlight the potential for repurposing disulfiram (also known by the trade name Antabuse), an old alcohol-aversion drug that has been shown to be effective against diverse cancer types in preclinical studies. Our nationwide epidemiological study reveals that patients who continuously used disulfiram have a lower risk of death from cancer compared to those who stopped using the drug at their diagnosis...
December 6, 2017: Nature
https://www.readbyqxmd.com/read/29206847/-gaining-or-losing-the-importance-of-the-perspective-in-primary-care-health-services-valuation
#3
Jesús Martín-Fernández, Gloria Ariza-Cardiel, Luz Mª Peña-Longobardo, Elena Polentinos-Castro, Juan Oliva-Moreno, Ana Isabel Gil-Lacruz, Héctor Medina-Palomino, Isabel Del Cura-González
RATIONALE AND OBJECTIVES: Economic theory classifies an intervention as socially beneficial if the total Willingness to Pay (WTP) of those who gain exceeds the total Willingness to accept (WTA) of those who are harmed. This paper examines the differences in health system users' valuation of a health care service in primary care setting based on the WTP and WTA perspectives, discussing the impact of personal and service variables, including risk attitudes, on these disparities. METHOD: Six hundred and sixty two subjects who asked for care in health centres in the Region of Madrid (Spain) were interviewed, using the contingent valuation method to estimate WTP and WTA...
2017: PloS One
https://www.readbyqxmd.com/read/29204908/posttraumatic-stress-disorder-due-to-acute-cardiac-events-and-aversive-cognitions-towards-cardiovascular-medications
#4
S Ali Husain, Donald Edmondson, Marin Kautz, Redeana Umland, Ian M Kronish
Posttraumatic stress disorder (PTSD) after acute medical events is associated with medication nonadherence. The mechanisms of PTSD-related nonadherence are poorly understood. We tested whether patients with elevated PTSD symptoms induced by suspected acute coronary syndrome (ACS) were more likely to have aversive cognitions towards cardiovascular medications. We enrolled a consecutive cohort of patients who presented to the emergency department with suspected ACS. One month after discharge, ACS-induced PTSD symptoms were assessed using the PTSD Checklist (PCL-S), and patients were asked "how often did" (1) "you miss your heart medication because you did not want to be reminded about your heart problem"; (2) "thinking about your heart medication make you feel nervous or anxious"; and (3) "thinking about your heart medication make you think about your risk for future heart problems...
December 4, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29203682/reasons-why-people-do-not-attend-nhs-health-checks-a-systematic-review-and-qualitative-synthesis
#5
Emma Harte, Calum MacLure, Adam Martin, Catherine L Saunders, Catherine Meads, Fiona M Walter, Simon J Griffin, Jonathan Mant, Juliet A Usher-Smith
BACKGROUND: The NHS Health Check programme is a prevention initiative offering cardiovascular risk assessment and management advice to adults aged 40-74 years across England. Its effectiveness depends on uptake. When it was introduced in 2009, it was anticipated that all those eligible would be invited over a 5-year cycle and 75% of those invited would attend. So far in the current cycle from 2013 to 2018, 33.8% of those eligible have attended, which is equal to 48.5% of those invited to attend...
December 4, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29200529/irrigation-risk-aversion-and-water-right-priority-under-water-supply-uncertainty
#6
Man Li, Wenchao Xu, Mark W Rosegrant
This paper explores the impacts of a water right's allocative priority-as an indicator of farmers' risk-bearing ability-on land irrigation under water supply uncertainty. We develop and use an economic model to simulate farmers' land irrigation decision and associated economic returns in eastern Idaho. Results indicate that the optimal acreage of land irrigated increases with water right priority when hydroclimate risk exhibits a negatively skewed or right-truncated distribution. Simulation results suggest that prior appropriation enables senior water rights holders to allocate a higher proportion of their land to irrigation, 6 times as much as junior rights holders do, creating a gap in the annual expected net revenue reaching up to $141...
September 2017: Water Resources Research
https://www.readbyqxmd.com/read/29198277/attention-deficit-hyperactivity-disorder-a-historical-neuropsychological-perspective
#7
E Mark Mahone, Martha B Denckla
The behavior patterns of hyperactivity, impulsivity and inattention that would ultimately become recognized as Attention-Deficit Hyperactivity Disorder (ADHD) have been described for centuries. Nevertheless, in the past 35 years, advances in diagnostic methods, identification of biomarkers, and treatments have advanced at an exponential rate. ADHD is now recognized as the most common behavioral disorder of childhood, with risks extending well into adulthood for both males and females, leading to its identification as a significant public health issue...
October 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29197689/action-research-and-millennials-improving-pedagogical-approaches-to-encourage-critical-thinking
#8
Gwen Erlam, Liz Smythe, Valerie Wright-St Clair
BACKGROUND: This article examines the effects of intergenerational diversity on pedagogical practice in nursing education. While generational cohorts are not entirely homogenous, certain generational features do emerge. These features may require alternative approaches in educational design in order to maximize learning for millennial students. METHOD: Action research is employed with undergraduate millennial nursing students (n=161) who are co-researchers in that they are asked for changes in current simulation environments which will improve their learning in the areas of knowledge acquisition, skill development, critical thinking, and communication...
November 24, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29174218/individual-differences-in-fear-relapse
#9
G King, B M Graham, R Richardson
Vulnerability to anxiety disorders might be due to enhanced acquisition of aversive associations, impaired inhibition of those associations (extinction), and/or vulnerability to the return of fear (relapse). Animal research investigating the processes underpinning fear learning, extinction, and relapse will be critical to further advancing our understanding of anxiety disorders and their treatment. Here we examined whether individual differences in the rate of extinction might be related to vulnerability to relapse...
November 20, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29169200/-german-language-version-and-validation-of-the-risk-taking-behaviour-scale-rbs-k-for-high-risk-sports
#10
Anika Frühauf, Martin Niedermeier, Gerhard Ruedl, Matthew Barlow, Tim Woodman, Martin Kopp
Background High-risk sports, particularly climbing, kayaking and extreme skiing, have become increasingly popular. The most widely used psychological survey instrument with regard to risk behaviour in sports is the Sensation Seeking Model, mostly assessed by the Sensation Seeking Scale (SSS-V). Until recently, the literature discussed risk behaviour solely through this model. However, this scale does not measure risk-taking behaviours. In contrast, the Risk-Taking Behaviour Scale (RBS-K) is a three-item scale that measures risk behaviour in high-risk sports...
November 23, 2017: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/29161963/age-differences-in-cognitive-flexibility-when-overcoming-a-preexisting-bias-through-feedback
#11
Cristina G Wilson, Amy T Nusbaum, Paul Whitney, John M Hinson
INTRODUCTION: Older adults are often worse than younger adults at adapting to changing situational demands, and this difference is commonly attributed to an age-related decline in acquiring and updating information. Previous research on aging and cognitive flexibility has used measures that require adapting to novel associations learned during a laboratory task (e.g., choice X led to positive outcomes but now leads to negative outcomes). However, in everyday life people must frequently overcome associations based on preexisting beliefs and biases (e...
November 21, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/29161629/the-effects-of-felbamate-on-appetitive-and-aversive-instrumental-learning-in-adult-rats
#12
John J Orczyk, Preston E Garraghty
Antiepileptic medications are the frontline treatment for seizure conditions but are not without cognitive side effects. Previously, our laboratory reported learning deficits in phenytoin-, carbamazepine-, and valproate-treated rats. In the present experiment, the effects of felbamate (FBM) have been compared to water-treated controls (controls) using the same instrumental training tasks employed here. Rats treated with FBM displayed a deficit in acquiring a tone-signaled avoidance response, relative to controls, but this was true only if they had no prior appetitive experience...
November 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29161193/infectious-disease-and-imperfections-of-self-image
#13
Joshua M Ackerman, Joshua M Tybur, Chad R Mortensen
Infectious disease is an ever-present threat in daily life. Recent literature indicates that people manage this threat with a suite of antipathogenic psychological and behavioral defense mechanisms, which motivate the avoidance of people and objects bearing cues to pathogen risk. Here, we demonstrate that self-image is also impacted by these mechanisms. In seven studies, pathogen cues led individuals chronically averse to germs to express greater concern about their own physical appearance. Correspondingly, these people exhibited behavioral intentions and decisions intended to conceal or improve their appearance, such as purchasing facial products, taking pharmaceuticals, and undergoing cosmetic surgery...
November 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/29156227/low-physiological-arousal-and-high-impulsivity-as-predictors-of-self-injurious-thoughts-and-behaviors-among-adolescents
#14
Jaclyn T Aldrich, Madeline D Wielgus, Amy H Mezulis
Self-injurious thoughts and behaviors are used to escape or regulate aversive physiological states during stress. Low sympathetic nervous system arousal during stress has been shown to confer risk. This risk may be exacerbated by trait impulsivity; adolescents high in impulsivity are more likely to rashly use maladaptive regulation strategies. We examined this relationship longitudinally in a sample of adolescents ages 10 to 14 (55.4% female) from the United States. Consistent with our hypothesis, low arousal during stress and high trait impulsivity interacted to predict the use of self-injurious thoughts and behaviors over a six-month period...
November 17, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/29155800/nicotinic-receptors-mediate-stress-nicotine-detrimental-interplay-via-dopamine-cells-activity
#15
C Morel, S P Fernandez, F Pantouli, F J Meye, F Marti, S Tolu, S Parnaudeau, H Marie, F Tronche, U Maskos, M Moretti, C Gotti, M-H Han, A Bailey, M Mameli, J Barik, P Faure
Epidemiological studies report strong association between mood disorders and tobacco addiction. This high comorbidity requires adequate treatment but the underlying mechanisms are unknown. We demonstrate that nicotine exposure, independent of drug withdrawal effects, increases stress sensitivity, a major risk factor in mood disorders. Nicotine and stress concur to induce long-lasting cellular adaptations within the dopamine (DA) system. This interplay is underpinned by marked remodeling of nicotinic systems, causing increased ventral tegmental area (VTA) DA neurons' activity and stress-related behaviors, such as social aversion...
July 25, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/29152417/assessing-mongolian-gerbil-emotional-behavior-effects-of-two-shock-intensities-and-response-independent-shocks-during-an-extended-inhibitory-avoidance-task
#16
Camilo Hurtado-Parrado, Camilo González-León, Mónica A Arias-Higuera, Angelo Cardona, Lucia G Medina, Laura García-Muñoz, Christian Sánchez, Julián Cifuentes, Juan Carlos Forigua, Andrea Ortiz, Cesar A Acevedo-Triana, Javier L Rico
Despite step-down inhibitory avoidance procedures that have been widely implemented in rats and mice to study learning and emotion phenomena, performance of other species in these tasks has received less attention. The case of the Mongolian gerbil is of relevance considering the discrepancies in the parameters of the step-down protocols implemented, especially the wide range of foot-shock intensities (i.e., 0.4-4.0 mA), and the lack of information on long-term performance, extinction effects, and behavioral patterning during these tasks...
2017: PeerJ
https://www.readbyqxmd.com/read/29151807/the-effect-of-acute-pain-on-risky-and-intertemporal-choice
#17
Lina Koppel, David Andersson, India Morrison, Kinga Posadzy, Daniel Västfjäll, Gustav Tinghög
Pain is a highly salient and attention-demanding experience that motivates people to act. We investigated the effect of pain on decision making by delivering acute thermal pain to participants' forearm while they made risky and intertemporal choices involving money. Participants (n = 107) were more risk seeking under pain than in a no-pain control condition when decisions involved gains but not when they involved equivalent losses. Pain also resulted in greater preference for immediate (smaller) over future (larger) monetary rewards...
2017: Experimental Economics
https://www.readbyqxmd.com/read/29149148/current-impact-and-application-of-abuse-deterrent-opioid-formulations-in-clinical-practice
#18
Ya-Han Lee, Daniel L Brown, Hsiang-Yin Chen
BACKGROUND: Abuse-deterrent formulations (ADFs) represent one novel strategy for curbing the potential of opioid abuse. OBJECTIVE: We aim to compare and contrast the characteristics and applications of current abuse-deterrent opioid products in clinical practice. METHODS: Literature searches were conducted in databases (Pubmed Medline, International Pharmaceutical Abstracts, Google Scholar) and official reports. Relevant data were screened and organized into: 1) epidemiology of opioid abuse, 2) mitigation strategies for reducing opioid abuse, 3) development of ADFs, and 4) clinical experience with these formulations...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29135565/pediatric-and-adolescent-anterior-shoulder-instability-clinical-management-of-first-time-dislocators
#19
Kenneth M Lin, Evan W James, Elad Spitzer, Peter D Fabricant
PURPOSE OF REVIEW: The purpose of this review is to discuss the epidemiology, pathoanatomy, diagnosis, and clinical management of pediatric and adolescent patients following a first-time shoulder dislocation. RECENT FINDINGS: Shoulder instability is becoming increasingly common as pediatric and adolescent patients engage in earlier organized sports competition. Recommended treatment following a first-time glenohumeral dislocation event in adolescents depends on several factors, but surgical stabilization is becoming more frequently performed...
November 11, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29131919/breast-feeding-friendly-but-not-formula-averse
#20
Juanita Lewis
Breast-feeding is the optimal source of newborn nutrition in term infants and is associated with multiple short- and long-term health benefits. Establishment of breast-feeding may be difficult in a small subset of mothers, which can lead to adverse consequences in the newborn. Some of the consequences of suboptimal nutritional provision to the newborn, such as severe hyperbilirubinemia and breast-feeding-associated hypernatremic dehydration, can have devastating and long-lasting sequelae. Timely identification of mothers and newborns at risk for developing these complications is necessary to avoid significant morbidity and mortality...
November 1, 2017: Pediatric Annals
keyword
keyword
108406
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"