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Risk aversion

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https://www.readbyqxmd.com/read/28545898/risk-averse-personalities-have-a-systemically-potentiated-neuroendocrine-stress-axis-a-multilevel-experiment-in-parus-major
#1
Alexander T Baugh, Rebecca A Senft, Marian Firke, Abigail Lauder, Julia Schroeder, Simone L Meddle, Kees van Oers, Michaela Hau
Hormonal pleiotropy-the simultaneous influence of a single hormone on multiple traits-has been hypothesized as an important mechanism underlying personality, and circulating glucocorticoids are central to this idea. A major gap in our understanding is the neural basis for this link. Here we examine the stability and structure of behavioral, endocrine and neuroendocrine traits in a population of songbirds (Parus major). Upon identifying stable and covarying behavioral and endocrine traits, we test the hypothesis that risk-averse personalities exhibit a neuroendocrine stress axis that is systemically potentiated-characterized by stronger glucocorticoid reactivity and weaker negative feedback...
May 22, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/28542198/optimization-of-black-box-models-with-uncertain-climatic-inputs-application-to-sunflower-ideotype-design
#2
Victor Picheny, Ronan Trépos, Pierre Casadebaig
Accounting for the interannual climatic variations is a well-known issue for simulation-based studies of environmental systems. It often requires intensive sampling (e.g., averaging the simulation outputs over many climatic series), which hinders many sequential processes, in particular optimization algorithms. We propose here an approach based on a subset selection in a large basis of climatic series, using an ad-hoc similarity function and clustering. A non-parametric reconstruction technique is introduced to estimate accurately the distribution of the output of interest using only the subset sampling...
2017: PloS One
https://www.readbyqxmd.com/read/28541522/response-to-comment-on-the-editorial-by-turner-et-al-on-assessment-of-cardiovascular-risk-of-new-drugs-for-the-treatment-of-diabetes-mellitus-risk-assessment-versus-risk-aversion-by-zannad-et-al
#3
Faiez Zannad
No abstract text is available yet for this article.
May 24, 2017: European Heart Journal. Cardiovascular Pharmacotherapy
https://www.readbyqxmd.com/read/28515474/blunted-ambiguity-aversion-during-cost-benefit-decisions-in-antisocial-individuals
#4
Joshua W Buckholtz, Uma Karmarkar, Shengxuan Ye, Grace M Brennan, Arielle Baskin-Sommers
Antisocial behavior is often assumed to reflect aberrant risk processing. However, many of the most significant forms of antisocial behavior, including crime, reflect the outcomes of decisions made under conditions of ambiguity rather than risk. While risk and ambiguity are formally distinct and experimentally dissociable, little is known about ambiguity sensitivity in individuals who engage in chronic antisocial behavior. We used a financial decision-making task in a high-risk community-based sample to test for associations between sensitivity to ambiguity, antisocial behavior, and arrest history...
May 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28514638/the-evolution-of-cooperation-interacting-phenotypes-among-social-partners
#5
Mat Edenbrow, Bronwyn H Bleakley, Safi K Darden, Charles R Tyler, Indar W Ramnarine, Darren P Croft
Models of cooperation among nonkin suggest that social assortment is important for the evolution of cooperation. Theory predicts that interacting phenotypes, whereby an individual's behavior depends on the behavior of its social partners, can drive such social assortment. We measured repeated indirect genetic effects (IGEs) during cooperative predator inspection in eight populations of Trinidadian guppies (Poecilia reticulata) that vary in their evolutionary history of predation. Four broad patterns emerged that were dependent on river, predation history, and sex: (i) current partner behavior had the largest effect on focal behavior, with fish from low-predation habitats responding more to their social partners than fish from high-predation habitats; (ii) different focal/partner behavior combinations can generate cooperation; (iii) some high-predation fish exhibited carryover effects across social partners; and (iv) high-predation fish were more risk averse...
June 2017: American Naturalist
https://www.readbyqxmd.com/read/28510736/go-no-go-decision-in-anaesthesia-wide-variation-in-risk-tolerance-amongst-anaesthetists
#6
P R Greig, H E Higham, J L Darbyshire, C Vincent
Background: The variability in risk tolerance in medicine is not well understood. Parallels are often drawn between aviation and anaesthesia. The aviation industry is perceived as culturally risk averse, and part of preflight checks involves a decision on whether the flight can operate. This is sometimes termed a go/no-go decision. This questionnaire study was undertaken to explore the equivalent go/no-go decision in anaesthesia. We presented anaesthetists with a range of situations in which additional risk might be expected and asked them to decide whether they would proceed with the case...
May 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28488149/identification-of-water-quality-management-policy-of-watershed-system-with-multiple-uncertain-interactions-using-a-multi-level-factorial-risk-inference-based-possibilistic-probabilistic-programming-approach
#7
Jing Liu, Yongping Li, Guohe Huang, Haiyan Fu, Junlong Zhang, Guanhui Cheng
In this study, a multi-level-factorial risk-inference-based possibilistic-probabilistic programming (MRPP) method is proposed for supporting water quality management under multiple uncertainties. The MRPP method can handle uncertainties expressed as fuzzy-random-boundary intervals, probability distributions, and interval numbers, and analyze the effects of uncertainties as well as their interactions on modeling outputs. It is applied to plan water quality management in the Xiangxihe watershed. Results reveal that a lower probability of satisfying the objective function (θ) as well as a higher probability of violating environmental constraints (q i ) would correspond to a higher system benefit with an increased risk of violating system feasibility...
May 9, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28484379/testosterone-and-cortisol-jointly-predict-the-ambiguity-premium-in-an-ellsberg-urns-experiment
#8
Giuseppe Danese, Eugénia Fernandes, Neil V Watson, Samuele Zilioli
Previous literature has tried to establish whether and how steroid hormones are related to economic risk-taking. In this study, we investigate the relationship between testosterone (T) and cortisol (C) on one side and attitudes toward risk and ambiguity on the other. We asked 78 male undergraduate students to complete several tasks and provide two saliva samples. In the task "Reveal the Bag," participants expressed their beliefs on an ambiguous situation in an incentivized framework. In the task "Ellsberg Bags," we elicited from the participants through an incentive-compatible mechanism the reservation prices for a risky bet and an ambiguous bet...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28479177/immunization-in-pregnancy-clinical-research-in-low-and-middle-income-countries-study-design-regulatory-and-safety-considerations
#9
Sonali Kochhar, Jan Bonhoeffer, Christine E Jones, Flor M Muñoz, Angel Honrado, Jorgen Bauwens, Ajoke Sobanjo-Ter Meulen, Steven Hirschfeld
Immunization of pregnant women is a promising public health strategy to reduce morbidity and mortality among both the mothers and their infants. Establishing safety and efficacy of vaccines generally uses a hybrid design between a conventional interventional study and an observational study that requires enrolling thousands of study participants to detect an unknown number of uncommon events. Historically, enrollment of pregnant women in clinical research studies encountered many barriers based on risk aversion, lack of knowledge, and regulatory ambiguity...
May 4, 2017: Vaccine
https://www.readbyqxmd.com/read/28450699/a-predation-cost-to-bold-fish-in-the-wild
#10
Kaj Hulthén, Ben B Chapman, P Anders Nilsson, Lars-Anders Hansson, Christian Skov, Jakob Brodersen, Jerker Vinterstare, Christer Brönmark
Studies of predator-mediated selection on behaviour are critical for our understanding of the evolution and maintenance of behavioural diversity in natural populations. Consistent individual differences in prey behaviour, especially in the propensity to take risks ("boldness"), are widespread in the animal kingdom. Theory predicts that individual behavioural types differ in a cost-benefit trade-off where bolder individuals benefit from greater access to resources while paying higher predation-risk costs. However, explicitly linking predation events to individual behaviour under natural conditions is challenging and there is currently little data from the wild...
April 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28444393/response-to-the-comment-on-the-editorial-by-turner-et-al-on-assessment-of-cardiovascular-risk-of-new-drugs-for-the-treatment-of-diabetes-mellitus-risk-assessment-vs-risk-aversion-by-zannad-et-al
#11
J Turner Rick, Erica Caveney
No abstract text is available yet for this article.
April 24, 2017: European Heart Journal. Cardiovascular Pharmacotherapy
https://www.readbyqxmd.com/read/28444250/comment-on-the-editorial-by-turner-et-al-on-assessment-of-cardiovascular-risk-of-new-drugs-for-the-treatment-of-diabetes-mellitus-risk-assessment-vs-risk-aversion-by-zannad-et-al
#12
Kristina Dunder, Pieter A de Graeff, Eberhard Blind
No abstract text is available yet for this article.
April 24, 2017: European Heart Journal. Cardiovascular Pharmacotherapy
https://www.readbyqxmd.com/read/28434586/the-periaqueductal-gray-and-primal-emotional-processing-critical-to-influence-complex-defensive-responses-fear-learning-and-reward-seeking
#13
REVIEW
Simone C Motta, Antônio P Carobrez, Newton S Canteras
The periaqueductal gray (PAG) has been commonly recognized as a downstream site in neural networks for the expression of a variety of behaviors and is thought to provide stereotyped responses. However, a growing body of evidence suggests that the PAG may exert more complex modulation of a number of behavioral responses and work as a unique hub supplying primal emotional tone to influence prosencephalic sites mediating complex aversive and appetitive responses. Of particular relevance, we review how the PAG is involved in influencing complex forms of defensive responses, such as circa-strike and risk assessment responses in animals...
May 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28431168/identifying-new-susceptibility-genes-on-dopaminergic-and-serotonergic-pathways-for-the-framing-effect-in-decision-making
#14
Xiaoxue Gao, Jinting Liu, Pingyuan Gong, Junhui Wang, Wan Fang, Hongming Yan, Lusha Zhu, Xiaolin Zhou
The framing effect refers the tendency to be risk-averse when options are presented positively but be risk-seeking when the same options are presented negatively during decision-making. This effect has been found to be modulated by the serotonin transporter gene (SLC6A4) and the catechol-o-methyltransferase gene (COMT) polymorphisms, which are on the dopaminergic and serotonergic pathways and which are associated with affective processing. The current study aimed to identify new genetic variations of genes on dopaminergic and serotonergic pathways that may contribute to individual differences in the susceptibility to framing...
April 19, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28416629/individual-differences-in-fear-extinction-and-anxiety-like-behavior
#15
Gabrielle King, Elliot Scott, Bronwyn M Graham, Rick Richardson
There is growing appreciation for the substantial individual differences in the acquisition and inhibition of aversive associations, and the insights this might give into identifying individuals particularly vulnerable to stress and psychopathology. We examined whether animals that differed in rate of extinction (i.e., Fast versus Slow) were different in their response to an acute stress in adulthood or following a chronic stress that occurred either early or later in life. We found that Slow Extinguishers had significantly poorer extinction retention than Fast Extinguishers, but an acute stressor did not differentially affect anxiety-like behavior in the two groups...
May 2017: Learning & Memory
https://www.readbyqxmd.com/read/28412226/expression-profiling-based-clustering-of-healthy-subjects-recapitulates-classifications-defined-by-clinical-observation-in-chinese-medicine
#16
Ruoxi Yu, Dan Liu, Yin Yang, Yuanyuan Han, Lingru Li, Luyu Zheng, Ji Wang, Yan Zhang, Yingshuai Li, Qian-Fei Wang, Qi Wang
Differences between healthy subjects and associated disease risks are of substantial interest in clinical medicine. Based on clinical presentations, Traditional Chinese Medicine (TCM) classifies healthy people into nine constitutions: Balanced, Qi, Yang or Yin deficiency, Phlegm-dampness, Damp-heat, Blood stasis, Qi stagnation, and Inherited special constitutions. In particular, Yang and Yin deficiency constitutions exhibit cold and heat aversion, respectively. However, the intrinsic molecular characteristics of unbalanced phenotypes remain unclear...
April 20, 2017: Journal of Genetics and Genomics, Yi Chuan Xue Bao
https://www.readbyqxmd.com/read/28411577/perceived-parental-child-rearing-and-attachment-as-predictors-of-anxiety-and-depressive-disorder-symptoms-in-children-the-mediational-role-of-attachment
#17
Paloma Chorot, Rosa M Valiente, Ana M Magaz, Miguel A Santed, Bonifacio Sandin
The present study aimed to examine (a) the relative contribution of perceived parental child-rearing behaviors and attachment on anxiety and depressive symptoms, and (b) the role of attachment as a possible mediator of the association between parental rearing and anxiety and depression. A sample of 1002 children (aged 9-12 years) completed a booklet of self-report questionnaires measuring parental rearing behaviors, attachment towards peers, and DSM anxiety and depressive disorder symptoms. We found that parental aversiveness, parental neglect, and fearful/preoccupied attachment, each accounted for a significant amount of the variance in both anxiety and depressive symptoms...
April 7, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28409566/combined-effects-of-glucocorticoid-and-noradrenergic-activity-on-loss-aversion
#18
Zsofia Margittai, Gideon Nave, Marijn Van Wingerden, Alfons Schnitzler, Lars Schwabe, Tobias Kalenscher
Loss aversion is a well-known behavioral regularity in financial decision-making, describing humans' tendency to overweigh losses compared to gains of the same amount. Recent research indicates that stress and associated hormonal changes affect loss aversion, yet the underlying neuroendocrine mechanisms are still poorly understood. Here, we investigated the causal influence of two major stress neuromodulators, cortisol and noradrenaline, on loss aversion during financial decision-making. In a double-blind, placebo-controlled between subject design, we orally administered either the α2-adrenergic antagonist yohimbine (increasing noradrenergic stimulation), hydrocortisone, both substances, or a placebo to healthy young men...
April 14, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28406375/who-dares-who-errs-disentangling-cognitive-and-motivational-roots-of-age-differences-in-decisions-under-risk
#19
Thorsten Pachur, Rui Mata, Ralph Hertwig
We separate for the first time the roles of cognitive and motivational factors in shaping age differences in decision making under risk. Younger and older adults completed gain, loss, and mixed-domain choice problems as well as measures of cognitive functioning and affect. The older adults' decision quality was lower than the younger adults' in the loss domain, and this age difference was attributable to the older adults' lower cognitive abilities. In addition, the older adults chose the more risky option more often than the younger adults in the gain and mixed domains; this difference in risk aversion was attributable to less pronounced negative affect among the older adults...
April 2017: Psychological Science
https://www.readbyqxmd.com/read/28401660/depression-anxiety-and-compulsive-sexual-behaviour-among-men-in-residential-treatment-for-substance-use-disorders-the-role-of-experiential-avoidance
#20
Meagan J Brem, Ryan C Shorey, Scott Anderson, Gregory L Stuart
Nearly one-third of individuals in treatment for substance use disorders endorse at-risk levels of compulsive sexual behaviours (CSBs). Untreated sexual compulsivity may facilitate relapse for treatment-seeking men. Previous research and theory suggest that CSBs are maintained by efforts to escape or alter negative affect (e.g., depression and anxiety). However, this hypothesis has not been examined within a sample of men in treatment for substance use disorders. In an effort to better understand CSBs within a population of men with substance use disorders, the present study is the first to examine experiential avoidance as one potential mechanism underlying the relation between men's symptoms of depression and anxiety and their use of CSBs...
April 11, 2017: Clinical Psychology & Psychotherapy
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