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Risk aversion

Darren E Stewart, Victoria C Garcia, John D Rosendale, David K Klassen, Bob J Carrico
BACKGROUND: The proportion of deceased donor kidneys recovered for transplant but discarded increased steadily in the U.S. over 2 decades, from 5.1% in 1988 to 19.2% by 2009. Over 100,000 patients are waiting for a kidney transplant, yet 3,159 kidneys were discarded in 2015. METHODS: We evaluated trends in donor characteristics, discard reasons, and OPO-specific discard rates. Multivariable regression and propensity analysis were used to estimate the proportion of the discard rate rise in the 2000's attributable to changes in donor factors and decisions to biopsy and pump kidneys...
October 19, 2016: Transplantation
Julian C Harnoss, Isabelle Zelienka, Pascal Probst, Kathrin Grummich, Catharina Müller-Lantzsch, Jonathan M Harnoss, Alexis Ulrich, Markus W Büchler, Markus K Diener
OBJECTIVE: The aim was to investigate available evidence regarding effectiveness and safety of surgical versus conservative treatment of acute appendicitis. SUMMARY OF BACKGROUND DATA: There is ongoing debate on the merits of surgical and conservative treatment for acute appendicitis. METHODS: A systematic literature search (Cochrane Library, Medline, Embase) and hand search of retrieved reference lists up to January 2016 was conducted to identify randomized and nonrandomized studies...
October 17, 2016: Annals of Surgery
Tushar M Ranchod, Chris A Jones
No abstract text is available yet for this article.
October 17, 2016: Retina
Anat Moed, Theodore Dix, Edward R Anderson, Shannon M Greene
Research is unclear about when expressing negative emotions to children performs valuable socialization and regulatory functions and when, instead, it undermines children's adjustment. In this study, we isolated 1 kind of negative expression to test the aversion sensitivity hypothesis: that rapid increases in mothers' negativity as a function of increases in the aversiveness of children's behavior are uniquely problematic for children. During multiple assessments of a divorcing sample over 2 years (N = 284), 12-min interactions between mothers and their 4- to 11-year-old children were recorded...
October 17, 2016: Journal of Family Psychology: JFP
Kenneth J Woodside, Randall S Sung
Transplantation is one of the most highly regulated fields in health care. An important component of transplant oversight is the performance assessment of transplant centers as measured by 1-year patient and graft survival outcomes. The use of the Organ Procurement and Transplantation Network and Scientific Registry of Transplant Recipients flagging mechanism for quality improvement as criteria for Center for Medicare and Medicaid Services certification has resulted in greater importance in transplant program operations...
September 2016: Advances in Chronic Kidney Disease
Alice R Norton, Maree J Abbott
BACKGROUND: A number of key environmental factors during childhood have been implicated in the aetiology of social anxiety disorder (SAD), including aversive social experiences, traumatic life events and parent-child interaction. However, understanding the nature, interactions and relative contributions of these factors remains unclear. Furthermore, the relation of aversive social experiences to the development of key maintaining factors in SAD requires elucidation. AIMS: The current study aimed to extend previous research regarding the aetiology of SAD by investigating the relationship between key environmental factors in childhood, negative beliefs and self-imagery, and the development of SAD...
October 11, 2016: Clinical Psychology & Psychotherapy
Arata Hidano, Tim E Carpenter, Mark A Stevenson, M Carolyn Gates
Many countries implement regionalisation as a measure to control economically important livestock diseases. Given that regionalisation highlights the difference in disease risk between animal subpopulations, this may discourage herd managers in low-risk areas from purchasing animals from high-risk areas to protect the disease-free status of their herds. Using bovine tuberculosis (bTB) in New Zealand as a case example, we develop a novel network simulation model to predict how much the frequency of cattle movements between different disease control areas (DCAs) could theoretically change if herd managers adopted the safest practices (preferentially purchasing cattle from areas with the lowest risk of bTB), if herd managers adopted the riskiest practices (preferentially purchasing cattle from areas with the greatest risk of bTB), or if herd managers made trade decisions completely at random (purchasing cattle without consideration for bTB disease risk)...
October 1, 2016: Preventive Veterinary Medicine
Tzahit Simon-Tuval, Amir Shmueli, Ilana Harman-Boehm
OBJECTIVES: To examine whether the degree of risk aversion is associated with adherence to disease self-management among adults with type 2 diabetes. METHODS: This was a cross-sectional study of patients with type 2 diabetes (n = 408) aged 21 to 70 years who presented for routine visits in the diabetes clinic at a university medical center in Beer-Sheva, Israel. The authors used validated questionnaires to estimate adherence, risk preferences, motivation, self-efficacy, impulsivity, perceptions about the disease and the interpersonal process of care, and demographic and socioeconomic characteristics, in addition to retrieving data from computerized patient medical records of clinical indicators of disease severity...
September 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Di Dong, Semra Ozdemir, Yong Mong Bee, Sue-Anne Toh, Marcel Bilger, Eric Finkelstein
OBJECTIVES: To investigate patient preferences and willingness to pay (WTP) for a genetic test that can reduce the risk of life-threatening adverse drug reactions (ADRs). We hypothesize that test features (risk of developing the adverse reaction with and without testing, test cost, and treatment cost) and the choice context (physician recommendation and the most common choice made by peer patients) will influence choices. METHODS: A discrete choice experiment was conducted in which 189 patients at high risk for gout were asked to choose between treatment options that varied along key attributes...
September 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Katharine S Gries, Dean A Regier, Scott D Ramsey, Donald L Patrick
OBJECTIVE: To develop a statistical model generating utility estimates for prostate cancer specific health states, using preference weights derived from the perspectives of prostate cancer patients, men at risk for prostate cancer, and society. METHODS: Utility estimate values were calculated using standard gamble (SG) methodology. Study participants valued 18 prostate-specific health states with the five attributes: sexual function, urinary function, bowel function, pain, and emotional well-being...
October 4, 2016: Applied Health Economics and Health Policy
Oriel FeldmanHall, Paul Glimcher, Augustus L Baker, Elizabeth A Phelps
Uncertainty, which is ubiquitous in decision-making, can be fractionated into known probabilities (risk) and unknown probabilities (ambiguity). Although research has illustrated that individuals more often avoid decisions associated with ambiguity compared to risk, it remains unclear why ambiguity is perceived as more aversive. Here we examine the role of arousal in shaping the representation of value and subsequent choice under risky and ambiguous decisions. To investigate the relationship between arousal and decisions of uncertainty, we measure skin conductance response-a quantifiable measure reflecting sympathetic nervous system arousal-during choices to gamble under risk and ambiguity...
October 2016: Journal of Experimental Psychology. General
X T Zeng, G H Huang, Y P Li, J L Zhang, Y P Cai, Z P Liu, L R Liu
This study developed a fuzzy-stochastic programming with Green Z-score criterion (FSGZ) method for water resources allocation and water quality management with a trading-mechanism (WAQT) under uncertainties. FSGZ can handle uncertainties expressed as probability distributions, and it can also quantify objective/subjective fuzziness in the decision-making process. Risk-averse attitudes and robustness coefficient are joined to express the relationship between the expected target and outcome under various risk preferences of decision makers and systemic robustness...
September 29, 2016: Environmental Science and Pollution Research International
Qingzhou Sun, Yongfang Liu, Huanren Zhang, Jingyi Lu
Individuals are consistently observed to be risk averse over gains and risk seeking over losses. This study examined whether increased social distance would change these behavioral patterns. To test our hypothesis, social distance was manipulated by asking the participants to make decisions either for themselves or for another person (Experiment 1), either for a known person or for an unknown person (Experiment 2), and either for a close friend or for a distant friend (Experiment 3). The results of Experiments 1 and 3 showed that increased social distance made people more risk neutral, and such an effect was stronger in the gain domain than in the loss domain...
September 29, 2016: Journal of Social Psychology
Jolie M Martin, Martin Reimann, Michael I Norton
Although many experiments have explored risk preferences for money, few have systematically assessed risk preferences for everyday experiences. We propose a conceptual model and provide convergent evidence from 7 experiments to suggest that, in contrast to a typical "zero" reference point for choices on money, reference points for choices of experiences are set at more extreme outcomes, leading to concave utility for negative experiences but convex utility for positive experiences. As a result, people are more risk-averse for negative experiences such as disgusting foods-as for monetary gains-but more risk-seeking for positive experiences such as desserts-as for monetary losses...
September 29, 2016: Journal of Experimental Psychology. General
Patricia M Lambert, Martin H Welker
OBJECTIVES: Bioarchaeological research has documented a general decline in health with the transition from foraging to farming, primarily with respect to changing patterns of morbidity. Less is known about changes in injury risk, an aspect of health more obviously tied to particular landscapes and behaviors associated with different subsistence regimes. The purpose of this research is to evaluate several hypotheses emerging from the ideal free distribution model (Fretwell & Lucas, ) that predict injury risk based on subsistence-specific practices and land use patterns...
September 27, 2016: American Journal of Physical Anthropology
Fioravante Capone, Gianluca Capone, Giovanni Di Pino, Lucia Florio, Gianluca Oricchio, Vincenzo Di Lazzaro
There is great interest about the individual differences that influence the ability of dealing with risky decisions. In this light, an intriguing question is whether decision-making during risk is related to other cognitive abilities, especially executive functions. To investigate, in healthy subjects, the existence of a possible correlation between risk-taking and cognitive abilities, the balloon analogue risk task (BART) has been exploited to assess risk-taking propensity and the random number generation (RNG), to investigate cognitive functions...
September 22, 2016: Neurological Sciences
Joerg Mahlich, Rosarin Sruamsiri
OBJECTIVE: To describe the usage of different biologic agents for rheumatoid arthritis (RA) in Japan over time and to identify factors that affects the decision to initiate treatment with biologic agents. Determinants of a switch to another biologic agent for patients who are already on biologic treatment were also analyzed. RESEARCH DESIGN AND METHODS: We utilized a hospital claims database containing 36,504 Japanese patients with a confirmed RA diagnosis. To analyze the determinants of treatment choices, we applied logistic regression analysis taking into account socio-demographic and medical factors...
October 3, 2016: Current Medical Research and Opinion
Justin R Yates, Kerry A Breitenstein, Benjamin T Gunkel, Mallory N Hughes, Anthony B Johnson, Katherine K Rogers, Sara M Shape
Risky decision making can be measured using a probability-discounting procedure, in which animals choose between a small, certain reinforcer and a large, uncertain reinforcer. Recent evidence has identified glutamate as a mediator of risky decision making, as blocking the N-methyl-d-aspartate (NMDA) receptor with MK-801 increases preference for a large, uncertain reinforcer. Because the order in which probabilities associated with the large reinforcer can modulate the effects of drugs on choice, the current study determined if NMDA receptor ligands alter probability discounting using ascending and descending schedules...
September 15, 2016: Pharmacology, Biochemistry, and Behavior
Vinay Kini, Rory B Weiner, Fenton H McCarthy, Susan E Wiegers, James N Kirkpatrick
BACKGROUND: Professional societies have made efforts to curb overuse of cardiac imaging and decrease practice variation by publishing appropriate use criteria. However, little is known about the impact of physician-level determinants such as liability concerns and risk aversion on decisions to order testing. METHODS: A web-based survey was administered to cardiologists and general practice physicians affiliated with two academic institutions. The survey consisted of four clinical scenarios in which appropriate use criteria rated echocardiography or stress testing as "may be appropriate...
September 14, 2016: Journal of the American Society of Echocardiography
Michelle Alvarado, Lewis Ntaimo
Oncology clinics are often burdened with scheduling large volumes of cancer patients for chemotherapy treatments under limited resources such as the number of nurses and chairs. These cancer patients require a series of appointments over several weeks or months and the timing of these appointments is critical to the treatment's effectiveness. Additionally, the appointment duration, the acuity levels of each appointment, and the availability of clinic nurses are uncertain. The timing constraints, stochastic parameters, rising treatment costs, and increased demand of outpatient oncology clinic services motivate the need for efficient appointment schedules and clinic operations...
September 16, 2016: Health Care Management Science
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