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pediatrics, neonatology, neurology

Carlo Caffarelli, Francesca Santamaria, Dora Di Mauro, Carla Mastrorilli, Virginia Mirra, Sergio Bernasconi
This review focuses key advances in different pediatric fields that were published in Italian Journal of Pediatrics and in international journals in 2015. Weaning studies continue to show promise for preventing food allergy. New diagnostic tools are available for identifying the allergic origin of allergic-like symptoms. Advances have been reported in obesity, short stature and autoimmune endocrine disorders. New molecules are offered to reduce weight gain and insulin-resistance in obese children. Regional investigations may provide suggestions for preventing short stature...
August 27, 2016: Italian Journal of Pediatrics
Christopher D Smyser, Emily W Y Tam, Taeun Chang, Janet S Soul, Steven P Miller, Hannah C Glass
BACKGROUND: Neonatal neurocritical care is a growing and rapidly evolving medical subspecialty, with increasing numbers of dedicated multidisciplinary clinical, educational, and research programs established at academic institutions. The growth of these programs has provided trainees in neurology, neonatology, and pediatrics with increased exposure to the field, sparking interest in dedicated fellowship training in fetal-neonatal neurology. OBJECTIVES: To meet this rising demand, increasing numbers of training programs are being established to provide trainees with the requisite knowledge and skills to independently deliver care for infants with neurological injury or impairment from the fetal care center and neonatal intensive care unit to the outpatient clinic...
October 2016: Pediatric Neurology
Liz Forbat, Charlotte Sayer, Phillip McNamee, Esse Menson, Sarah Barclay
BACKGROUND: Conflict in healthcare is a well-recognised but under-examined phenomenon. Little is known about the prevalence and causes of conflict across paediatric specialties. OBJECTIVE: To report the frequency and characteristics of conflict in a paediatric hospital. DESIGN AND SETTING: An explanatory sequential mixed-method approach was adopted. A bespoke questionnaire recorded frequency, severity, cause and staff involved in conflict prospectively...
January 2016: Archives of Disease in Childhood
G Arveladze, N Geladze, N Khachapuridze, S Bakhtadze, N Kapanadze
Mitochondrial diseases are considered as one of the major problems of modern interdisciplinary neonatology and pediatrics. Mitochondrial pathology can be revealed as refractory myoclonic or multifocal seizures, craniofacial dysostosis, dysmetabolic manifestations and respiratory disorders. Central nervous system (CNS), muscles, heart, liver and kidneys is involved in this pathological process. An important criterion for diagnosis of mitochondrial dysfunction is increases in blood lactate and pyruvate levels; the absolute criterion - molecular genetic diagnostic studies of mitochondrial DNA...
July 2015: Georgian Medical News
M Paoletti, M-N Litnhouvongs, J Tandonnet
INTRODUCTION: In France, a legal framework and guidelines state that decisions to limit treatments (DLT) require a collaborative decision meeting and a transcription of decisions in the patient's file. The do-not-attempt-resuscitation order involves the same decision-making process for children in palliative care. To fulfill the law's requirements and encourage communication within the teams, the Resource Team in Pediatric Palliative Care in Aquitaine created a document shared by all children's hospital units, tracing the decision-making process...
May 2015: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Carlo Caffarelli, Francesca Santamaria, Alessandra Vottero, Carlotta Povesi Dascola, Virginia Mirra, Francesco Sperli, Sergio Bernasconi
This review will provide new information related to pathophysiology and management of specific diseases that have been addressed by selected articles published in the Italian Journal of Pediatrics in 2013, focusing on allergology, endocrinology, gastroenterology, hypertension, infectious diseases, neonatology, neurology, nutrition and respiratory tract illnesses in children. Recommendations for interpretation of skin prick test to foods in atopic eczema, management of allergic conjunctivitis, hypertension and breastfeeding in women treated with antiepileptic drugs and healthy breakfast have been reported...
2014: Italian Journal of Pediatrics
Nermeen M Galal
BACKGROUND: Intravenous Immunoglobulin (IVIG) preparations are scarce biological products used for replacement or immunomodulatory effects. Guidelines have been issued by regulatory health authorities to ensure provision of the products for patients who are in severe need. OBJECTIVES: The study aimed at description of the pattern of IVIG use (label/off label indications), adverse effects observed, reason for choice of IVIG among other modalities and efficacy in a pediatric intensive care setting...
June 2013: African Health Sciences
Courtney J Wusthoff
The neurological exam can be a challenging part of a newborn's full evaluation. At the same time, the neonatal neurological exam is a useful tool in identifying babies needing closer evaluation for potential problems. The Dubowitz assessment is a standardised approach to the neonatal neurological exam designed for use by paediatricians in routine practice. Evidence has validated this technique and delineated its utility as a screening exam in various populations. This paper reviews clinical application of the Dubowitz assessment of the newborn...
August 2013: Archives of Disease in Childhood. Education and Practice Edition
María Luisa Martín-Ruiz, Miguel Ángel Valero Duboy, Iván Pau de la Cruz
Neuro-evolutive development from birth until the age of six years is a decisive factor in a child's quality of life. Early detection of development disorders in early childhood can facilitate necessary diagnosis and/or treatment. Primary-care pediatricians play a key role in its detection as they can undertake the preventive and therapeutic actions requested to promote a child's optimal development. However, the lack of time and little specific knowledge at primary-care avoid to applying continuous early-detection anomalies procedures...
2013: Sensors
Sascha Meyer, Christiane Willhelm, Wolfgang Girisch, Sven Gottschling, Stefan Gräber, Ludwig Gortner
BACKGROUND: There is a lack of up-to-date, systematic reviews that critically assess the role and potential limitations of evidence-based medicine and systematic Cochrane reviews originating in developing countries. METHODS: We performed a systematic literature review of all Cochrane reviews published between 1997 and 2010 by the Cochrane Neonatal Review Group (CNRG) in the field of neuropediatrics. The main outcome parameter of our review was the assessment of the percentage of reviews that originated in developing countries and the number of reviews that provided conclusive/ inconclusive data...
2013: World Health & Population
Daniel Alonso-Alconada, Antonia Alvarez, Olatz Arteaga, Agustín Martínez-Ibargüen, Enrique Hilario
One of the most common causes of mortality and morbidity in children is perinatal hypoxia-ischemia (HI). In spite of the advances in neonatology, its incidence is not diminishing, generating a pediatric population that will require an extended amount of chronic care throughout their lifetime. For this reason, new and more effective neuroprotective strategies are urgently required, in order to minimize as much as possible the neurological consequences of this encephalopathy. In this sense, interest has grown in the neuroprotective possibilities of melatonin, as this hormone may help to maintain cell survival through the modulation of a wide range of physiological functions...
2013: International Journal of Molecular Sciences
Sascha Meyer, Nicole Schroeder, Christiane Willhelm, Ludwig Gortner, Wolfgang Girisch
No abstract text is available yet for this article.
June 2013: Pediatrics International: Official Journal of the Japan Pediatric Society
K Joost, R J Rodenburg, A Piirsoo, L van den Heuvel, R Zordania, H Põder, I Talvik, K Kilk, U Soomets, K Ounap
Mitochondrial disorders are a heterogeneous group of disorders affecting energy production of the body. Different consensus diagnostic criteria for mitochondrial disorders in childhood are available - Wolfson, Nijmegen and modified Walker criteria. Due to the extreme complexity of mitochondrial disorders in children, we decided to develop a diagnostic algorithm, applicable in clinical practice in Estonia, in order to identify patients with mitochondrial disorders among pediatric neonatology and neurology patients...
September 2012: Molecular Syndromology
Edibe Pembegul Yıldız, Burak Tatlı, Barış Ekici, Emine Eraslan, Nur Aydınlı, Mine Calışkan, Meral Ozmen
This study evaluated etiologic and risk factors affecting long-term prognoses of neurologic outcomes in newborns with neonatal seizures. We enrolled patients at chronologic ages of 23-44 months, referred to the Department of Pediatric Neurology, Istanbul Medical Faculty, from January 1, 2007-December 31, 2009, after manifesting seizures in their first postnatal 28 days. Of 112 newborns, 41 were female, 71 were male, 33 were preterm, and 79 were full-term. Perinatal asphyxia (28.6%) and intracranial hemorrhage (17%) were the most common causes of neonatal seizures...
September 2012: Pediatric Neurology
Yaseen Joolay, Michael C Harrison, Alan R Horn
BACKGROUND: Recent newborn resuscitation guidelines recommend therapeutic hypothermia (TH) as a treatment to reduce long-term neurological deficit in hypoxic ischemic encephalopathy (HIE) survivors. In South Africa, varied resource constraints may present difficulties in the implementation of TH. OBJECTIVE: To determine the opinions and practice of South African pediatricians, regarding TH and the management of HIE. METHODS: We invited 288 South African pediatricians and neonatologists to participate in a web-based survey by e-mail...
June 2012: Journal of Perinatal Medicine
Ronald A Bronicki, David S Cooper
The practice of pediatric cardiac intensive care depends on a collaborative effort from all disciplines involved in the care of critically ill pediatric patients with cardiovascular disease. The 8th International Conference of the Pediatric Cardiac Intensive Care Society was reflective of this collaborative effort as experts from several disciplines, including neonatology, critical care, cardiology, neurology, anesthesia and surgery, gathered to discuss the latest advances in the care of pediatric cardiovascular disease, beginning with the fetus and extending into adulthood...
March 2011: Expert Review of Cardiovascular Therapy
F Sessions Cole, Claudia Alleyne, John D E Barks, Robert J Boyle, John L Carroll, Deborah Dokken, William H Edwards, Michael Georgieff, Katherine Gregory, Michael V Johnston, Michael Kramer, Christine Mitchell, Josef Neu, DeWayne M Pursley, Walter Robinson, David H Rowitch
OBJECTIVE: To provide healthcare providers, patients, and the general public with a responsible assessment of currently available data on the use of inhaled nitric oxide in early routine, early rescue, or later rescue regimens in the care of premature infants <34 weeks gestation who require respiratory support. PARTICIPANTS: A non-Department of Health and Human Services, nonadvocate 16-member panel representing the fields of biostatistics, child psychology, clinical trials, ethics, family-centered care, neonatology, neurodevelopmental follow-up, nursing, pediatric epidemiology, neurobehavior, neurological surgery, neurology, and pulmonology, perinatology, and research methodology...
October 29, 2010: NIH Consensus and State-of-the-science Statements
Ling Xu, Jie Hao, Min Deng, Yan-ying Xu
OBJECTIVE: To understand the projects completion and research progresses in pediatrics which were funded by the National Natural Science Foundation of China (NSFC), and evaluate the accomplishment objectively and justly. METHODS: The completion status of projects in pediatrics funded by department of clinical medicine II from 2002 to 2006 was analysed retrospectively, and important research achievement and outstanding development in some projects were reported. RESULTS: During the period between 2002 and 2006, 420 articles were published, and the average was 8...
May 2009: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
J A Munoz-Yunta
No abstract text is available yet for this article.
December 1, 2007: Revista de Neurologia
A Valcamonico, P Accorsi, C Sanzeni, P Martelli, P La Boria, A Cavazza, T Frusca
OBJECTIVE: To evaluate morbidity and long-term neurological outcome in a group of extremely low birth weight infants (ELBW; <1000 g) and to correlate the neurological outcome in a small group of intrauterine growth retarded (IUGR) infants with Doppler indices in the umbilical artery. METHODS: One hundred and eighty-three live births with birth weight <1000 g and gestational age < or=34 weeks were included in the study. Neonatal mortality and morbidity were evaluated...
June 2007: Journal of Maternal-fetal & Neonatal Medicine
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