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https://www.readbyqxmd.com/read/28330429/effects-of-inhaled-aerosolized-carfentanil-on-real-time-physiological-responses-in-mice-a-preliminary-evaluation-of-naloxone
#1
Benjamin Wong, Michael W Perkins, Justin Tressler, Ashley Rodriguez, Jennifer Devorak, Alfred M Sciuto
This study examined the real-time exposure-response effects of aerosolized carfentanil (CRF) on opioid-induced toxicity, respiratory dynamics and cardiac function in mice. Unrestrained, conscious male CD-1 mice (25-30 g) were exposed to 0.4 or 4.0 mg/m(3) of aerosolized CRF for 15 min (Ct = 6 or 60 mg min/m(3)) in a whole-body plethysmograph chamber. Minute volume (MV), core body temperature (Tc), mean arterial blood pressure (MAP) and heart rate (HR) were evaluated in animals exposed to CRF or sterile H2O...
February 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/28329750/optoelectronic-plethysmography-in-clinical-practice-and-research-a-review
#2
Carlo Massaroni, Elena Carraro, Andrea Vianello, Sandra Miccinilli, Michelangelo Morrone, Irisz K Levai, Emiliano Schena, Paola Saccomandi, Silvia Sterzi, John W Dickinson, Samantha Winter, Sergio Silvestri
BACKGROUND: Optoelectronic plethysmography (OEP) is a non-invasive motion capture method to measure chest wall movements and estimate lung volumes. OBJECTIVES: To provide an overview of the clinical findings and research applications of OEP in the assessment of breathing mechanics across populations of healthy and diseased individuals. METHODS: A bibliographic research was performed with the terms "opto-electronic plethysmography," "optoelectronic plethysmography," and "optoelectronic plethysmograph" in 50 digital library and bibliographic search databases resulting in the selection of 170 studies...
March 23, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28318340/characteristic-plethysmographic-findings-in-a-guinea-pig-model-of-copd
#3
Edgar Ramírez-Ramírez, Armando Torres-Ramírez, Jesús Alquicira-Mireles, Abraham Cañavera-Constantino, Patricia Segura-Medina, Martha Montaño-Ramírez, Carlos Ramos-Abraham, Mario H Vargas, José Luis Arreola-Ramírez
AIM OF THE STUDY: Long-term exposure to cigarette smoke generates chronic obstructive pulmonary disease (COPD) in guinea pigs, but a comprehensive evaluation of changes in lung function, as assessed by barometric whole body plethysmography (WBP), is lacking. MATERIALS AND METHODS: Female guinea pigs were exposed to the smoke of 20 cigarettes/day, 5 days/week, during 10 weeks (COPD group, n = 8), and were compared with unexposed female guinea pigs of the same age (control group, n = 8)...
March 20, 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/28294169/comparison-of-body-adiposity-index-bai-and-air-displacement-plethysmograph-with-estimations-of-body-fat-in-adults-with-down-s-syndrome
#4
M Rossato, R A Dellagrana, E de Souza Bezerra, R M da Costa, J O L Dos Santos, D A S Silva, F Diefenthaeler
BACKGROUND/OBJECTIVES: The aim of this study was to verify the agreement between body fat percentage (%BF) values evaluated by air displacement plethysmograph (ADP) and body adiposity index (BAI) in adults with Down's syndrome (DS). SUBJECTS/METHODS: Forty-five adults with DS volunteered to participate in this study (19 women; age 28.7±8.5 years and 26 men; age 29.1±8.8 years). The %BF was measured by ADP (%BFADP) and estimated by anthropometric measures [%BF=(hip circumference/height)(1...
March 15, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28289632/hemodynamic-adaptations-to-regular-exercise-in-people-with-spinal-cord-injury
#5
Young Hee Lee, Jin Hyeong Lee, Sung Hoon Kim, Dongsoo Yi, Kyung Joon Oh, Ji Hyun Kim, Tae Jun Park, Hanul Kim, Jae Seung Chang, In Deok Kong
OBJECTIVE: To investigate the real-time cardiovascular response to the progressive overload exercise in different levels of spinal cord injury (SCI), and to find out whether regular exercise has effect on these cardiovascular responses. METHODS: The study enrolled 8 able-bodied individuals in the control group plus 15 SCI subjects who were divided into two groups by their neurological level of injury: high-level SCI group (T6 or above) and low-level SCI group (T7 or below)...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28269362/non-invasive-heart-rate-monitoring-system-using-giant-magneto-resistance-sensor
#6
Kubera Kalyan, Vinit Kumar Chugh, C S Anoop
A simple heart rate (HR) monitoring system designed and developed using the Giant Magneto-Resistance (GMR) sensor is presented in this paper. The GMR sensor is placed on the wrist of the human and it provides the magneto-plethysmographic signal. This signal is processed by the simple analog and digital instrumentation stages to render the heart rate indication. A prototype of the system has been built and test results on 26 volunteers have been reported. The error in HR estimation of the system is merely 1 beat per minute...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268792/feasibility-study-of-a-giant-magneto-resistance-based-respiration-rate-monitor
#7
Vinit Kumar Chugh, Kubera Kalyan, C S Anoop
This paper reports a simple and reliable electronic technique for the estimation of respiration rate (RR). Giant Magneto-Resistance (GMR) based sensors are employed to extract a plethysmograph signal from the subject. This signal is filtered and processed further through simple signal processing stages to obtain RR indication. The feasibility of the system has been studied on a prototype built and associated experimentation on 20 volunteers. The developed system provided clean plethysmographic signals, whose relevant features are shown to possess a relation with RR...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268478/comparison-of-pulse-rate-variability-and-heart-rate-variability-for-high-frequency-content-estimation
#8
R Logier, J De Jonckheere, A Dassonneville, M Jeanne
Heart Rate Variability (HRV) analysis can be of precious help in most of clinical situations because it is able to quantify the Autonomic Nervous System (ANS) activity. The HRV high frequency (HF) content, related to the parasympathetic tone, reflects the ANS response to an external stimulus responsible of pain, stress or various emotions. We have previously developed the Analgesia Nociception Index (ANI), based on HRV high frequency content estimation, which quantifies continuously the vagal tone in order to guide analgesic drug administration during general anesthesia...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28245206/cerebrovascular-and-cardiovascular-variability-interactions-investigated-through-conditional-joint-transfer-entropy-in-subjects-prone-to-postural-syncope
#9
Vlasta Bari, Beatrice De Maria, Claudio Enrico Mazzucco, Gianluca Rossato, Davide Tonon, Giandomenico Nollo, Luca Faes, Alberto Porta
A model-based conditional transfer entropy approach was exploited to quantify the information transfer in cerebrovascular (CBV) and cardiovascular (CV) systems in subjects prone to develop postural syncope. Spontaneous beat-to-beat variations of mean cerebral blood flow velocity (MCBFV) derived from a transcranial Doppler device, heart period (HP) derived from surface electrocardiogram, mean arterial pressure (MAP) and systolic arterial pressure (SAP) derived from finger plethysmographic arterial pressure device were monitored at rest in supine position (REST) and during 60° head-up tilt (TILT) in 13 individuals (age mean±standard deviation: 28±9 years, min-max range: 18-44 years, 5 males) with a history of recurrent episodes of syncope (SYNC) and in 13 age- and gender-matched controls (NonSYNC)...
February 28, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28227604/non-invasive-heart-rate-monitoring-system-using-giant-magneto-resistance-sensor
#10
Kubera Kalyan, Vinit Kumar Chugh, C S Anoop, Kubera Kalyan, Vinit Kumar Chugh, C S Anoop, Vinit Kumar Chugh, Kubera Kalyan, C S Anoop
A simple heart rate (HR) monitoring system designed and developed using the Giant Magneto-Resistance (GMR) sensor is presented in this paper. The GMR sensor is placed on the wrist of the human and it provides the magneto-plethysmographic signal. This signal is processed by the simple analog and digital instrumentation stages to render the heart rate indication. A prototype of the system has been built and test results on 26 volunteers have been reported. The error in HR estimation of the system is merely 1 beat per minute...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226986/feasibility-study-of-a-giant-magneto-resistance-based-respiration-rate-monitor
#11
Vinit Kumar Chugh, Kubera Kalyan, C S Anoop, Vinit Kumar Chugh, Kubera Kalyan, C S Anoop, Kubera Kalyan, C S Anoop
This paper reports a simple and reliable electronic technique for the estimation of respiration rate (RR). Giant Magneto-Resistance (GMR) based sensors are employed to extract a plethysmograph signal from the subject. This signal is filtered and processed further through simple signal processing stages to obtain RR indication. The feasibility of the system has been studied on a prototype built and associated experimentation on 20 volunteers. The developed system provided clean plethysmographic signals, whose relevant features are shown to possess a relation with RR...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226651/comparison-of-pulse-rate-variability-and-heart-rate-variability-for-high-frequency-content-estimation
#12
R Logier, J De Jonckheere, A Dassonneville, M Jeanne, R Logier, J De Jonckheere, A Dassonneville, M Jeanne, A Dassonneville, J De Jonckheere, R Logier, M Jeanne
Heart Rate Variability (HRV) analysis can be of precious help in most of clinical situations because it is able to quantify the Autonomic Nervous System (ANS) activity. The HRV high frequency (HF) content, related to the parasympathetic tone, reflects the ANS response to an external stimulus responsible of pain, stress or various emotions. We have previously developed the Analgesia Nociception Index (ANI), based on HRV high frequency content estimation, which quantifies continuously the vagal tone in order to guide analgesic drug administration during general anesthesia...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222636/change-in-pulse-transit-time-in-the-lower-extremity-after-lumbar-sympathetic-ganglion-block-an-early-indicator-of-successful-block
#13
Eun-Young Joo, Yu Gyeong Kong, Jonghyuk Lee, Hyun-Seok Cho, Sung-Hoon Kim, Jeong Hun Suh
Objective To investigate the change in pulse transit time (PTT)-time between the electrocardiographic R wave and the highest point of the corresponding plethysmographic wave-after lumbar sympathetic ganglion block (LSGB) and evaluate PTT as an indicator of successful LSGB. Methods Sixteen cases of sympathetically mediated lower extremity neuropathic pain treated with LSGB were studied. Correlations between the changes in PTT and temperature were used to identify the cutoff point indicating successful LSGB. Results PTT rate of change at 5 min relative to the baseline PTT (dPTT5/PTT0) significantly correlated positively with the temperature change at 20 min (correlation coefficient 0...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28220077/noninvasive-assessment-of-the-effect-of-position-and-exercise-on-pulse-arrival-to-peripheral-vascular-beds-in-healthy-volunteers
#14
Yurie Obata, Qi J Ong, J T Magruder, Helen Grichkevitch, Dan E Berkowitz, Daniel Nyhan, Jochen Steppan, Viachaslau Barodka
Background: The effects of position and exercise on pulse wave distribution across a healthy, compliant arterial tree are not fully understood. We studied the effects of exercise and position on the pattern of pulse arrival times (PATs) in healthy volunteers. Moreover, we compared the pulse arrival time ratios to the respective distance ratios between different locations. Methods: Thirteen young healthy volunteers were studied, using an electrocardiogram and plethysmograph to simultaneously record pulse wave arrival at the ear lobe, index finger and big toe...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28153424/seizure-associated-central-apnea-in-a-rat-model-evidence-for-resetting-the-respiratory-rhythm-and-activation-of-the-diving-reflex
#15
S M Villiere, K Nakase, R Kollmar, J Silverman, K Sundaram, M Stewart
Respiratory derangements, including irregular, tachypnic breathing and central or obstructive apnea can be consequences of seizure activity in epilepsy patients and animal models. Periods of seizure-associated central apnea, defined as periods >1s with rapid onset and offset of no airflow during plethysmography, suggest that seizures spread to brainstem respiratory regions to disrupt breathing. We sought to characterize seizure-associated central apneic episodes as an indicator of seizure impact on the respiratory rhythm in rats anesthetized with urethane and given parenteral kainic acid to induce recurring seizures...
May 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28092917/is-fat-mass-accretion-of-late-preterm-infants-associated-with-insulin-resistance
#16
Nadia Liotto, Maria Lorella Giannì, Francesca Taroni, Paola Roggero, Chiara Cristiana Condello, Anna Orsi, Camilla Menis, Riccardo Bonfanti, Fabio Mosca
BACKGROUND: Late preterm infants show a major fat mass accretion from birth to term. The contribution of preterm birth to the development of the metabolic syndrome is still under investigation. OBJECTIVES: To evaluate body composition changes in late preterm infants during the first 3 months and to investigate their insulin sensitivity and resistance. METHODS: We conducted an observational, longitudinal study. A total of 216 late preterm infants underwent body composition assessment using an air displacement plethysmograph at term and at 3 months of corrected age...
January 17, 2017: Neonatology
https://www.readbyqxmd.com/read/28009638/the-effect-of-head-rotation-on-efficiency-of-face-mask-ventilation-in-anaesthetised-apnoeic-adults-a-prospective-randomised-crossover-study
#17
Taiga Itagaki, Jun Oto, Sara M Burns, Yandong Jiang, Robert M Kacmarek, Jeremi R Mountjoy
BACKGROUND: Upper airway obstruction occurs commonly after induction of general anaesthesia. It is the major cause of difficult mask ventilation. OBJECTIVES: The aim of this study was to determine whether head rotation improves the efficiency of mask ventilation of anaesthetised apnoeic adults. DESIGN: A prospective crossover study. SETTING: Single university teaching hospital. PATIENTS: Forty patients, aged 18 to 75 years with a BMI 18...
December 22, 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/27998692/squill-oxymel-a-traditional-formulation-from-drimia-maritima-l-stearn-as-an-add-on-treatment-in-patients-with-moderate-to-severe-persistent-asthma-a-pilot-triple-blind-randomized-clinical-trial
#18
Fatemeh Nejatbakhsh, Hossein Karegar-Borzi, Gholamreza Amin, Alireza Eslaminejad, Mostafa Hosseini, Mahbubeh Bozorgi, Mehrnaz Asadi Gharabaghi
ETHNOPHARMACOLOGICAL RELEVANCE: In Traditional Iranian Medicine (TIM), Squill (Drimia maritima (L.) Stearn) Oxymel was utilized in the treatment of asthma. Squill has been reported to exert anti-inflammatory, anti-oxidant, anti-cholinergic, and mucus secretion modulating effects. OBJECTIVE: This study aimed to make a preliminary evaluation of the efficacy and safety of an add-on Squill Oxymel treatment in patients with moderate to severe persistent asthma. METHODS: In a 6-week, triple-blind, randomized, placebo-controlled trial, 60 patients with stable moderate to severe persistent asthma were randomly allocated to receive either 10ml syrup of Squill Oxymel, simple oxymel, or a placebo 2 times a day, as an add-on to their routine treatment (inhaled corticosteroids and β2 agonists)...
January 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27989888/trpv4-antagonist-gsk2193874-does-not-modulate-cough-response-to-osmotic-stimuli
#19
Tomas Buday, Lea Kovacikova, Robert Ruzinak, Jana Plevkova
Osmolarity changes of airway superficial fluid are associated with cough and are used in research. TRPV4 is calcium channel initially described as osmosensor. In the airways, it can play role in increasing cough reflex sensitivity. The aim of our study was to test whether cough to osmotic stimuli is mediated via TRPV4 channel. Cough response was measured in 12 male guinea pigs by inhalation of saline, distilled water, hypertonic solution and citric acid for 10min in whole-body plethysmograph. Data were obtained in naïve animals and after pre-treatment with selective TRPV4 antagonist GSK2193874 in doses 300μg/kg (GSK300) and 900μg/kg (GSK900)...
February 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/27855687/diagnostic-accuracy-of-methacholine-challenge-tests-assessing-airway-hyperreactivity-in-asthmatic-patients-a-multifunctional-approach
#20
Richard Kraemer, Hans-Jürgen Smith, Thomas Sigrist, Gabi Giger, Roland Keller, Martin Frey
BACKGROUND: There are few studies comparing diagnostic accuracy of different lung function parameters evaluating dose-response characteristics of methacholine (MCH) challenge tests (MCT) as quantitative outcome of airway hyperreactivity (AHR) in asthmatic patients. The aim of this retrospectively analysis of our database (Clinic Barmelweid, Switzerland) was, to assess diagnostic accuracy of several lung function parameters quantitating AHR by dose-response characteristics. METHODS: Changes in effective specific airway conductance (sGeff) as estimate of the degree of bronchial obstruction were compared with concomitantly measured forced expiratory volume in 1 s (FEV1) and forced expiratory flows at 50% forced vital capacity (FEF50)...
November 17, 2016: Respiratory Research
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