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https://www.readbyqxmd.com/read/29203173/evaluation-of-the-dynamic-predictors-of-fluid-responsiveness-in-dogs-receiving-goal-directed-fluid-therapy
#1
Maja J Drozdzynska, Yu-Mei Chang, Giacomo Stanzani, Ludovic Pelligand
OBJECTIVES: Goal-directed fluid therapy (GDFT) based on pulse pressure variation (PPV) was used in anaesthetized dogs undergoing abdominal surgeries. The aims were 1) to evaluate the success rate of the PPV ≥13% in detecting fluid responsiveness [delta stroke volume (ΔSV) ≥10%]; 2) to assess the correlation between PPV, systolic pressure variation (SPV), Plethysmograph Variability Index (PVI) and central venous pressure (CVP) and 3) to establish the threshold value for the PVI that would predict a PPV value of ≥13% and indirectly discriminate responders from nonresponders to fluid therapy...
June 17, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29189318/standardised-noxious-stimulation-guided-individual-adjustment-of-remifentanil-target-controlled-infusion-to-prevent-haemodynamic-responses-to-laryngoscopy-and-surgical-incision-a-randomised-controlled-trial
#2
Aline Defresne, Luc Barvais, François Clement, Vincent Bonhomme
BACKGROUND: The surgical plethysmographic index (SPI) is one of the available indexes of the nociception-antinociception (NAN) balance. Individually adjusting the NAN balance to prevent somatic responses to noxious stimulation remains a challenge. OBJECTIVES: To assess whether guiding remifentanil administration according to the SPI response to a calibrated noxious stimulus (NANCAL) can blunt the haemodynamic response to tracheal intubation and surgical incision...
November 18, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29183008/correlates-of-pulmonary-function-in-children-with-sickle-cell-disease-and-elevated-fetal-hemoglobin
#3
Adekunle D Adekile, Asmaa Azab, Abdullah Owayed, Mousa Khadadah
OBJECTIVE: The current study was carried out to compare pulmonary function tests (PFT) in pediatric Kuwaiti sickle cell disease (SCD) patients to age-matched normal controls and to investigate the association of PFTS to selected clinical and laboratory parameters. SUBJECTS AND METHODS: There were 38 patients with SCD and 36 controls in the study. The patients were recruited from the Pediatric Hematology Clinics of Mubarak Al-Kabeer and Al-Amiri Hospitals, Kuwait and were studied in steady state...
November 28, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29163200/a-pulse-wave-velocity-based-method-to-assess-the-mean-arterial-blood-pressure-limits-of-autoregulation-in-peripheral-arteries
#4
Ananya Tripathi, Yurie Obata, Pavel Ruzankin, Narwan Askaryar, Dan E Berkowitz, Jochen Steppan, Viachaslau Barodka
Background: Constant blood flow despite changes in blood pressure, a phenomenon called autoregulation, has been demonstrated for various organ systems. We hypothesized that by changing hydrostatic pressures in peripheral arteries, we can establish these limits of autoregulation in peripheral arteries based on local pulse wave velocity (PWV). Methods: Electrocardiogram and plethysmograph waveforms were recorded at the left and right index fingers in 18 healthy volunteers. Each subject changed their left arm position, keeping the right arm stationary...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29122914/pulmonary-function-deficits-in-newborn-screened-infants-with-cystic-fibrosis-managed-with-standard-uk-care-are-mild-and-transient
#5
Gwyneth Davies, Janet Stocks, Lena P Thia, Ah-Fong Hoo, Andrew Bush, Paul Aurora, Lucy Brennan, Simon Lee, Sooky Lum, Philippa Cottam, Joanne Miles, Jane Chudleigh, Jane Kirkby, Ian M Balfour-Lynn, Siobhán B Carr, Colin Wallis, Hilary Wyatt, Angie Wade
With the advent of novel designer molecules for cystic fibrosis (CF) treatment, there is huge need for early-life clinical trial outcomes, such as infant lung function (ILF). We investigated the degree and tracking of ILF abnormality during the first 2 years of life in CF newborn screened infants.Forced expiratory volume in 0.5 s (FEV0.5), lung clearance index (LCI) and plethysmographic functional residual capacity were measured at ∼3 months, 1 year and 2 years in 62 infants with CF and 34 controls...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29119007/endothelial-dysfunction-is-associated-with-activation-of-the-type-i-interferon-system-and-platelets-in-patients-with-systemic-lupus-erythematosus
#6
Helena Tydén, Christian Lood, Birgitta Gullstrand, Christoffer Tandrup Nielsen, Niels H H Heegaard, Robin Kahn, Andreas Jönsen, Anders A Bengtsson
Objectives: Endothelial dysfunction may be connected to cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). Type I interferons (IFNs) are central in SLE pathogenesis and are suggested to induce both endothelial dysfunction and platelet activation. In this study, we investigated the interplay between endothelial dysfunction, platelets and type I IFN in SLE. Methods: We enrolled 148 patients with SLE and 79 sex-matched and age-matched healthy controls (HCs)...
2017: RMD Open
https://www.readbyqxmd.com/read/29111029/hematoma-volume-is-a-predictive-factor-of-disturbed-autoregulation-after-spontaneous-intracerebral-hemorrhage
#7
Hongyin Ma, Zhen-Ni Guo, Xin Sun, Jia Liu, Shan Lv, Lu Zhao, Weitong Guo, Hang Jin, Yi Yang
BACKGROUND: Dynamic cerebral autoregulation (dCA) is probably disturbed after spontaneous intracerebral hemorrhage (ICH) and could be an independent predictor of clinical outcome. Clinical determinants of dCA status after ICH need to be further elucidated. METHODS: We finally enrolled 53 patients diagnosed with supratentorial ICH within 6days from onset. DCA was assessed 4-6days after ICH onset by monitoring middle cerebral artery blood flow velocities and simultaneous arterial blood pressure continuously, utilizing transcranial Doppler combined with a servo-controlled finger plethysmograph...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29099251/effect-of-brachycephaly-and-body-condition-score-on-respiratory-thermoregulation-of-healthy-dogs
#8
Michael S Davis, Sabrina L Cummings, Mark E Payton
OBJECTIVE To evaluate the effect of brachycephaly and body condition score on respiratory thermoregulation of healthy dogs. DESIGN Prospective study. ANIMALS 52 brachycephalic and 53 nonbrachycephalic dogs. PROCEDURES All dogs were exposed to a cool treatment (temperature, 21.8 ± 1.7°C [71.2 ± 3.1°F]; relative humidity, 62.2 ± 9.7%; and ambient enthalpy, 47.7 ± 6.6 kcal/kg) and then a hot treatment (temperature, 32.9 ± 1.7°C [91.2 ± 3.1°F]; relative humidity, 51.9 ± 9.8%; and ambient enthalpy, 74...
November 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29060515/physical-activity-classification-using-time-frequency-signatures-of-motion-artifacts-in-multi-channel-electrical-impedance-plethysmographs
#9
Hassan Aqeel Khan, Amit Gore, Jeff Ashe, Shantanu Chakrabartty
Physical activities are known to introduce motion artifacts in electrical impedance plethysmographic (EIP) sensors. Existing literature considers motion artifacts as a nuisance and generally discards the artifact containing portion of the sensor output. This paper examines the notion of exploiting motion artifacts for detecting the underlying physical activities which give rise to the artifacts in question. In particular, we investigate whether the artifact pattern associated with a physical activity is unique; and does it vary from one human-subject to another? Data was recorded from 19 adult human-subjects while conducting 5 distinct, artifact inducing, activities...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060214/analysis-of-a-gmr-based-plethysmograph-transducer-and-its-utility-for-real-time-blood-pressure-measurement
#10
Vinit Kumar Chugh, Kubera Kalyan, C S Anoop, Amit Patra, Shubham Negi
The paper presents study and analysis of a Giant Magneto Resistance (GMR)-based magneto plethysmograph and illustrates its efficacy as a tool for real-time cuff-less measurement of Blood Pressure (BP). The proposed scheme employs two GMR sensors and associated biasing and signal conditioning in its architecture. The delay between output of the GMR sensors is used to estimate the BP. The methodology, circuits and signal processing stages used are described in the paper. A prototype of the GMR-sensing solution is developed and tested...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060142/classification-of-voluntary-coughs-applied-to-the-screening-of-respiratory-disease
#11
Christian Infante, Daniel B Chamberlain, Rahul Kodgule, Richard Ribon Fletcher
Pulmonary and respiratory diseases (e.g. asthma, COPD, allergies, pneumonia, tuberculosis, etc.) represent a large proportion of the global disease burden, mortality, and disability. In this context of creating automated diagnostic tools, we explore how the analysis of voluntary cough sounds may be used to screen for pulmonary disease. As a clinical study, voluntary coughs were recorded using a custom mobile phone stethoscope from 54 patients, of which 7 had COPD, 15 had asthma, 11 had allergic rhinitis, 17 had both asthma and allergic rhinitis, and four had both COPD and allergic rhinitis...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28981568/assessment-of-dynamic-variables-of-fluid-responsiveness-to-predict-desufflation-induced-hypotension-during-paediatric-laparoscopic-surgery
#12
E-H Kim, J-H Lee, I-K Song, H-G Ryu, H-S Kim, J-T Kim
Background: During laparoscopic surgery in paediatric patients, sudden hypotension may occur following peritoneal desufflation due to hypovolaemia or an acute increase in gastrointestinal venous capacitance by the release of intra-abdominal pressure. This study examined whether dynamic variables of fluid responsiveness during pneumoperitoneum can predict the occurrence of hypotension following desufflation. Methods: A total of 120 paediatric subjects were prospectively enrolled...
November 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28940503/measuring-arterial-blood-pressure-in-humans-auscultatory-and-automatic-measurement-techniques-for-human-biological-field-studies
#13
Gary D James, Linda M Gerber
Human biologists have been examining arterial blood pressure since they began studying the effects of the environment and culture on the health of diverse populations. The Korotkoff auscultatory technique with a trained observer and aneroid sphygmomanometer is the method of choice for blood pressure measurement in many bioanthropological field contexts. Korotkoff sounds (the first and fifth phases) are the preferred determinants of systolic and diastolic pressure, even in infants, children, pregnant women, and the elderly...
September 22, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28871670/-early-detection-of-endothelial-dysfunction-in-children-with-autoimmune-diseases-by-a-novel-noninvasive-technique
#14
Liron Borenstein-Levin, Riva Brik, Giora Pillar, Yonatan Butbul Aviel
INTRODUCTION: Atherosclerosis is emerging as one of the most important causes of morbidity and mortality among patients with different rheumatologic disease. Endothelial dysfunction may be an early sign of atherosclerosis. OBJECTIVES: To evaluate the occurrence of endothelial dysfunction in children with autoimmune diseases, including juvenile idiopathic arthritis (JIA), systemic lupus erythematosus (SLE) and dermatomyositis, using a novel noninvasive technique...
July 2017: Harefuah
https://www.readbyqxmd.com/read/28866598/a-magnetic-plethysmograph-probe-for-local-pulse-wave-velocity-measurement
#15
Nabeel P M, Jayaraj Joseph, Mohanasankar Sivaprakasam
OBJECTIVE: We present the design and experimental validation of an arterial compliance probe with dual magnetic plethysmograph (MPG) transducers for local pulse wave velocity (PWV) measurement. The MPG transducers (positioned at 23 mm distance apart) utilizes Hall-effect sensors and permanent magnets for arterial blood pulse detection. METHODS: The MPG probe was initially validated on an arterial flow phantom using a reference method. Further, 20 normotensive subjects (14 males, age = 24 ± 3...
October 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28861941/early-follow-up-of-lung-disease-in-infants-with-cystic-fibrosis-using-the-raised-volume-rapid-thoracic-compression-technique-and-computed-tomography-during-quiet-breathing
#16
Rémi Gauthier, Yann Cabon, Marie Agnes Giroux-Metges, Cecile Du Boisbaudry, Phillipe Reix, Muriel Le Bourgeois, Raphael Chiron, Nicolas Molinari, Magali Saguintaah, Francis Amsallem, Stefan Matecki
BACKGROUND: Among the different techniques used to monitor lung disease progression in infants with CF diagnosed by Newborn screening (NBS), raised volume-rapid thoracic compression (RVRTC) remains a promising tool. However, the need of sedation and positive pressure ventilation considerably limits its clinical use. We recently described a semi-quantitative method to evaluate air trapping by chest tomography during quite breathing without sedation (CTqb score). This parameter is the radiological sign of airway obstruction and could be also used for lung disease follow-up in infants with CF...
October 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28838793/the-impact-of-glottal-configuration-on-speech-breathing
#17
Elizabeth S Heller Murray, Carolyn M Michener, Laura Enflo, Gabriel J Cler, Cara E Stepp
OBJECTIVE: The purpose of this study was to examine whether changes in respiratory patterns occurred in response to volitional changes in glottal configuration. METHODS: Twelve vocally healthy participants read a passage while wearing the Inductotrace respiratory inductive plethysmograph, which measures the excursions of the rib cage and abdomen. Participants read the passage 5 times in a typical speaking voice (baseline phase), 10 times in an experimental voice, which was similar to a breathy vocal quality (experimental phase), and 5 times again in a typical speaking voice (return phase)...
August 21, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28775070/elevated-airway-liquid-volumes-at-birth-a-potential-cause-of-transient-tachypnea-of-the-newborn
#18
Erin Victoria McGillick, Katie Lee, Shigeo Yamaoka, Arjan B Te Pas, Kelly J Crossley, Megan J Wallace, Marcus John Kitchen, Robert A Lewis, Lauren T Kerr, Philip DeKoninck, Janneke Dekker, Marta Thio, Annie McDougall, Stuart B Hooper
Excessive liquid in airways and/or in distal lung tissue may underpin the respiratory morbidity associated with transient tachypnea of the newborn (TTN). However, its effects on lung aeration and respiratory function following birth are unknown. We investigated the effect of elevated airway liquid volumes on newborn respiratory function. Near term rabbit kittens (30 days gestation; term ~32 days) were delivered, had lung liquid drained and either had no liquid replaced (Control, n=7) or 30 mL/kg of liquid was re-added to the airways (liquid added; LA, n=7)...
August 3, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28775068/active-sleep-unmasks-apnea-and-delayed-arousal-in-infant-rat-pups-lacking-central-serotonin
#19
Jacob O Young, Aron Geurts, Matthew R Hodges, Kevin J Cummings
Sudden infant death syndrome (SIDS), occurring during sleep periods, is highly associated with abnormalities within serotonin (5-HT) neurons, including reduced 5-HT. There is evidence that future SIDS cases experience more apnea and have abnormal arousal from sleep. In rodents, a loss of 5-HT neurons is associated with apnea in early life and, in adulthood, delayed arousal. As the activity of 5-HT neurons changes with vigilance state, we hypothesized that the degree of apnea and delayed arousal displayed by rat pups specifically lacking central 5-HT varies with state...
October 1, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28750019/comparison-of-activity-and-fatigue-of-the-respiratory-muscles-and-pulmonary-characteristics-between-post-polio-patients-and-controls-a-pilot-study
#20
COMPARATIVE STUDY
David Shoseyov, Tali Cohen-Kaufman, Isabella Schwartz, Sigal Portnoy
OBJECTIVES: To compare pulmonary function measures, maximal respiratory pressure and fatigue of respiratory muscles between patients with Post-Polio Syndrome (PPS) and controls. DESIGN: Cross-sectional study. PATIENTS: Patients with PPS (N = 12; age 62.1±11.6 years) able to walk for 6 minutes without human assistance; age-matched controls with no history of polio or pulmonary dysfunction (N = 12; age 62.2±6.5 years). MEASUREMENTS: A body plethysmograph was used to quantify Residual Volume (RV), Total Lung Capacity (TLC), and Thoracic Gas Volume (TGV) etc...
2017: PloS One
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