keyword
MENU ▼
Read by QxMD icon Read
search

Spinal cord implants

keyword
https://www.readbyqxmd.com/read/28227566/somatosensory-encoding-with-cuneate-nucleus-microstimulation-detection-of-artificial-stimuli
#1
Srihari Y Sritharan, Andrew G Richardson, Pauline K Weigand, Ivette Planell-Mendez, Xilin Liu, Hongjie Zhu, Milin Zhang, Jan Van der Spiegel, Timothy H Lucas, Srihari Y Sritharan, Andrew G Richardson, Pauline K Weigand, Ivette Planell-Mendez, Xilin Liu, Hongjie Zhu, Milin Zhang, Jan Van der Spiegel, Timothy H Lucas, Srihari Y Sritharan, Andrew G Richardson, Milin Zhang, Jan Van der Spiegel, Pauline K Weigand, Xilin Liu, Timothy H Lucas, Hongjie Zhu, Ivette Planell-Mendez
The sense of touch and proprioception are critical to movement control. After spinal cord injury, these senses may be restored with direct, electrical microstimulation of the brain as part of a complete sensorimotor neuroprosthesis. The present study was designed to test, in part, the hypothesis that the cuneate nucleus (CN) of the brainstem is a suitable site to encode somatosensory information. Two rhesus macaques were implanted with microelectrode arrays providing chronic access to the CN. The monkeys were trained on an active touch oddity task to detect vibrotactile stimuli...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227510/feasibility-of-an-ultra-low-power-digital-signal-processor-platform-as-a-basis-for-a-fully-implantable-brain-computer-interface-system
#2
Po T Wang, Keulanna Gandasetiawan, Colin M McCrimmon, Alireza Karimi-Bidhendi, Charles Y Liu, Payam Heydari, Zoran Nenadic, An H Do, Po T Wang, Keulanna Gandasetiawan, Colin M McCrimmon, Alireza Karimi-Bidhendi, Charles Y Liu, Payam Heydari, Zoran Nenadic, An H Do, An H Do, Zoran Nenadic, Colin M McCrimmon, Keulanna Gandasetiawan, Payam Heydari, Alireza Karimi-Bidhendi, Po T Wang, Charles Y Liu
A fully implantable brain-computer interface (BCI) can be a practical tool to restore independence to those affected by spinal cord injury. We envision that such a BCI system will invasively acquire brain signals (e.g. electrocorticogram) and translate them into control commands for external prostheses. The feasibility of such a system was tested by implementing its benchtop analogue, centered around a commercial, ultra-low power (ULP) digital signal processor (DSP, TMS320C5517, Texas Instruments). A suite of signal processing and BCI algorithms, including (de)multiplexing, Fast Fourier Transform, power spectral density, principal component analysis, linear discriminant analysis, Bayes rule, and finite state machine was implemented and tested in the DSP...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227096/prediction-of-forelimb-muscle-emgs-from-the-corticospinal-signals-in-rats
#3
Sinan Gok, Mesut Sahin, Sinan Gok, Mesut Sahin, Sinan Gok, Mesut Sahin
To generate voluntary forearm movements, the information that is encoded in the activity of the cortical neurons has to travel through the spinal cord and activate the skeletal muscles. The axons carrying these signals are tightly bundled together in the descending tracts that control the spinal circuitry innervating the forearm muscles. In this paper, we show that corticospinal tract (CST) signals can be used to predict forearm electromyographic (EMG) activities that are recorded during an isometric-pull task...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225648/safety-of-autologous-human-schwann-cell-transplantation-in-subacute-thoracic-spinal-cord-injury
#4
Kimberly D Anderson, James Guest, W Dalton Dietrich, Mary B Bunge, Rosie Curiel, Marine Dididze, Barth A Green, Aisha Khan, Damien D Pearse, Efrat Saraf-Lavi, Eva Widerstrom-Noga, Pat Wood, Allan D Levi
The rationale for implantation of autologous human Schwann cells (SCs) in people with subacute spinal cord injury (SCI) is based on evidence that transplanted SCs are neuroprotective, support local axonal plasticity, and are capable of myelinating axons. A Phase I clinical trial was conducted to evaluate the safety of autologous human SC transplantation into the injury epicenter of six subjects with subacute SCI. The trial was an open-label, unblinded, non-randomized, non-placebo controlled study with a dose escalation design and standard medical rehabilitation...
February 18, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28220823/treatment-of-stress-urinary-incontinence-in-men-with-spinal-cord-injury-minimally-invasive-minimally-effective
#5
J Pannek, J Wöllner
STUDY DESIGN: Retrospective chart review. OBJECTIVES: To assess the outcome of minimally invasive treatment of stress urinary incontinence with alloplastic slings in patients with neurogenic lower urinary tract dysfunction. SETTING: Switzerland. METHODS: The patient database of a tertiary urologic referral center was screened for male patients with SCI who underwent implantation of a suburethral sling between June 2009 and December 2015...
February 21, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28215570/the-cardiac-electrophysiology-of-patients-with-spinal-cord-injury
#6
Michael Manogue, David S Hirsh, Michael Lloyd
Spinal cord injury (SCI) is a clinical syndrome encountered frequently in trauma centers and is accompanied by both acute and chronic heart rhythm abnormalities. The injury is characterized by sympathetic nervous system (SNS) impairment with preservation of parasympathetic output via the vagus nerve. Severe bradycardia in the form of life-threatening sinus arrest or complete heart block may be observed in the acute recovery phase. Therapy for arrhythmias in the acute phase includes atropine, intravenous chronotropes, methylxanthines for prevention of episodic bradycardia, and pacemaker implantation in severe cases...
February 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28215399/restoring-standing-capabilities-with-feedback-control-of-functional-neuromuscular-stimulation-following-spinal-cord-injury
#7
REVIEW
Raviraj Nataraj, Musa L Audu, Ronald J Triolo
This paper reviews the field of feedback control for neuroprosthesis systems that restore advanced standing function to individuals with spinal cord injury. Investigations into closed-loop control of standing by functional neuromuscular stimulation (FNS) have spanned three decades. The ultimate goal for FNS standing control systems is to facilitate hands free standing and enabling the user to perform manual functions at self-selected leaning positions. However, most clinical systems for home usage currently only provide basic upright standing using preprogrammed stimulation patterns...
February 15, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28205332/explantation-rates-and-healthcare-resource-utilization-in-spinal-cord-stimulation
#8
Jing L Han, Kelly R Murphy, Syed Mohammed Qasim Hussaini, Siyun Yang, Beth Parente, Jichun Xie, Promila Pagadala, Shivanand P Lad
OBJECTIVES: Certain patients ultimately undergo explantation of their spinal cord stimulation (SCS) devices. Understanding the predictors and rates of SCS explantation has important implications for healthcare resource utilization (HCRU) and pain management. The present study identifies explant predictors and discerns differences in HCRU for at-risk populations. METHODS: We designed a large, retrospective analysis using the Truven MarketScan Database. We included all adult patients who underwent a SCS trial from 2007 to 2012...
February 15, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28191306/chiropractic-management-of-post-spinal-cord-stimulator-spine-pain-a-case-report
#9
Rachel M Perrucci, Christopher M Coulis
BACKGROUND: A brief overview of failed back surgery syndrome, with emphasis on low back pain status post spinal cord stimulation, and post-surgical spinal manipulation is presented. CASE PRESENTATION: Four cases of patients within the VA Connecticut Health Care System presenting between July 2014 and July 2015 reporting low back pain after surgical insertion of spinal cord stimulators are discussed. This study describes the outcomes experienced by four patients with low back pain status post implanted spinal cord stimulators receiving manual therapy in the form of lumbar spine manipulation or mobilization...
2017: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/28186470/image-guidance-based-on-mri-for-spinal-interstitial-laser-thermotherapy-technical-aspects-and-accuracy
#10
Claudio E Tatsui, Clarissa N G Nascimento, Dima Suki, Behrang Amini, Jing Li, Amol J Ghia, Jonathan G Thomas, R Jason Stafford, Laurence D Rhines, Juan P Cata, Ashok J Kumar, Ganesh Rao
OBJECTIVE Image guidance for spinal procedures is based on 3D-fluoroscopy or CT, which provide poor visualization of soft tissues, including the spinal cord. To overcome this limitation, the authors developed a method to register intraoperative MRI (iMRI) of the spine into a neuronavigation system, allowing excellent visualization of the spinal cord. This novel technique improved the accuracy in the deployment of laser interstitial thermal therapy probes for the treatment of metastatic spinal cord compression...
February 10, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28185669/electrical-stimulation-and-monitoring-devices-of-the-cns-an-imaging-review
#11
REVIEW
Sohil H Patel, Casey H Halpern, Timothy M Shepherd, Vincent M Timpone
Functional neurosurgery is a rapidly growing field with exciting future potential applications. This article describes currently used implanted electronic devices for neurologic stimulation and monitoring. The devices to be reviewed include invasive EEG electrodes, deep brain stimulator, motor cortex stimulator, responsive neurostimulation, osteo-integrated hearing aid, middle ear implant, cochlear implant, auditory brainstem implant, vagal nerve stimulator and spinal cord stimulator. Emphasis is placed on the normal components, function, positioning, potential complications and MRI safety of these devices...
February 6, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28185615/clinical-study-of-neuroregen-scaffold-combined-with-human-mesenchymal-stem-cells-for-the-repair-of-chronic-complete-spinal-cord-injury
#12
Yannan Zhao, Fengwu Tang, Guang Han, Nuo Wang, Na Yin, Bing Chen, Xianfeng Jiang, Chen Yun, Wanjun Han, Changyu Zhao, Shixiang Cheng, Zhifeng Xiao, Sai Zhang, Jianwu Dai
Regeneration of damaged neurons and recovery of sensation and motor function after complete spinal cord injury (SCI) are challenging. We previously developed a collagen scaffold, NeuroRegen scaffold, to promote axonal growth along collagen fibers and inhibit glial scar formation after SCI. When functionalized with multiple biomolecules, this scaffold promoted neurological regeneration and functional recovery in animals with SCI. In this study, eight patients with chronic complete SCI were enrolled to examine the safety and efficacy of implanting NeuroRegen scaffold with human umbilical cord mesenchymal stem cells (MSCs)...
February 9, 2017: Cell Transplantation
https://www.readbyqxmd.com/read/28175473/178%C3%A2-high-abbreviated-injury-scale-grade-conversion-rate-following-neuro-spinal-scaffold-implantation-in-acute-thoracic-complete-abbreviated-injury-scale-a-spinal-cord-injury-potential-mechanisms
#13
Nicholas Theodore, Kee Duk Kim, Patrick C Hsieh, Wilson Zachary Ray, Maureen Barry, Rick Layer, Simon W Moore, Domagoj Coric
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28168635/imaging-of-post-surgical-treatment-and-of-related-complications-in-spinal-trauma
#14
REVIEW
F Caranci, G Leone, L Ugga, E Cesarano, R Capasso, S Schipani, A Bianco, P Fonio, F Briganti, L Brunese
Spinal trauma is a devastating event with a high morbidity and mortality. The rationale of imaging is to diagnose the traumatic abnormalities and characterize the type of injury, to estimate the severity of the lesions, to evaluate the potential spinal instability. In case of spinal instability, the goals of operative treatment are decompression of the spinal cord canal and stabilization of the disrupted vertebral column. Particularly, diagnostic imaging, mainly by CT and MR, has a main role in the post-treatment evaluation...
February 6, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28167393/biodegradable-scaffolds-promote-tissue-remodeling-and-functional-improvement-in-non-human-primates-with-acute-spinal-cord-injury
#15
Jonathan R Slotkin, Christopher D Pritchard, Brian Luque, Janice Ye, Richard T Layer, Mathew S Lawrence, Timothy M O'Shea, Roland R Roy, Hui Zhong, Isabel Vollenweider, V Reggie Edgerton, Grégoire Courtine, Eric J Woodard, Robert Langer
Tissue loss significantly reduces the potential for functional recovery after spinal cord injury. We previously showed that implantation of porous scaffolds composed of a biodegradable and biocompatible block copolymer of Poly-lactic-co-glycolic acid and Poly-l-lysine improves functional recovery and reduces spinal cord tissue injury after spinal cord hemisection injury in rats. Here, we evaluated the safety and efficacy of porous scaffolds in non-human Old-World primates (Chlorocebus sabaeus) after a partial and complete lateral hemisection of the thoracic spinal cord...
January 25, 2017: Biomaterials
https://www.readbyqxmd.com/read/28158157/successful-long-term-nerve-root-stimulation-for-chronic-neuropathic-pain-a-real-world-single-center-canadian-experience
#16
Adrian B Levine, David A Steven, Andrew G Parrent, Keith W MacDougall
BACKGROUND: Spinal cord stimulation (SCS) is a well-established treatment for chronic neuropathic pain in the lower limbs. However, some patients have pain in distributions that are difficult to target specifically and consistently with SCS. This often involves pain in the groin or upper limbs, or pain limited to a specific dermatome. We hypothesized that dorsal nerve root stimulation (DNRS) would provide similar pain relief for these patients, compared to our results using SCS. OBJECTIVES: In this study we report our experience treating patients with chronic neuropathic pain using SCS and DNRS...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28155591/impact-of-an-implanted-neuroprosthesis-on-community-ambulation-in-incomplete-sci
#17
Lisa M Lombardo, Rudolf Kobetic, Gilles Pinault, Kevin M Foglyano, Stephanie N Bailey, Stephen Selkirk, Ronald J Triolo
OBJECTIVE: Test the effect of a multi-joint control with implanted electrical stimulation on walking after spinal cord injury (SCI). DESIGN: Single subject research design with repeated measures Setting: Hospital-based biomechanics laboratory and user assessment of community use. PARTICIPANTS: Female with C6 AIS C SCI 30 years post injury. INTERVENTIONS: Lower extremity muscle activation with an implanted pulse generator and gait training...
February 3, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28153621/thoracic-radiculopathy-following-spinal-cord-stimulator-implantation-treated-with-corticosteroids
#18
Ritam Ghosh, Ryan Holland, Antonios Mammis
INTRODUCTION: Spinal cord stimulation has been used since 1967 to manage chronic neuropathic pain. Although effective, the literature describes the complication rate to be as high as 35%. One rare complication following spinal cord stimulator (SCS) implantation is the development of radicular pain. We present a case series of 2 patients implanted with SCSs who developed thoracic radiculopathy following implantation that resolved with corticosteroids. CASE DETAILS: Although this complication was previously thought to require surgical intervention, this case series describes the use of corticosteroids to resolve postimplantation thoracic radiculopathy...
January 31, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28147248/prolonged-stimulation-of-a-brainstem-raphe-region-attenuates-experimental-autoimmune-encephalomyelitis
#19
Pernille M Madsen, Stephanie S Sloley, Alberto A Vitores, Melissa M Carballosa-Gautam, Roberta Brambilla, Ian D Hentall
Multiple sclerosis (MS), a neuroinflammatory disease, has few treatment options, none entirely adequate. We studied whether prolonged electrical microstimulation of a hindbrain region (the nucleus raphe magnus) can attenuate experimental autoimmune encephalomyelitis, a murine model of MS induced by MOG35-55 injection. Eight days after symptoms emerged, a wireless electrical stimulator with an attached microelectrode was implanted cranially, and daily intermittent stimulation was begun in awake, unrestrained mice...
January 29, 2017: Neuroscience
https://www.readbyqxmd.com/read/28146294/shunt-tube-placement-for-amelioration-of-cerebrospinal-fluid-flow-obstruction-caused-by-spinal-cord-subarachnoid-fibrosis-in-dogs
#20
Ilyssa L Meren, Jessica A Chavera, Cody J Alcott, Andrew K Barker, Nick D Jeffery
OBJECTIVE: To describe a novel technique for ameliorating cerebrospinal fluid flow obstruction secondary to pia-arachnoid fibrosis in dogs and report outcome. STUDY DESIGN: Descriptive report and retrospective case series. ANIMALS: Dogs with cerebrospinal fluid (CSF) flow obstruction (n = 7). METHODS: Medical records were searched for dogs that had a subarachnoid-subarachnoid shunt placed for treatment of CSF flow obstruction...
February 2017: Veterinary Surgery: VS
keyword
keyword
108386
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"