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W Du, G Chen, D Bai, C Xue, W Fei, E Luo
Severe skeletal open bite associated with posterior vertical maxillary excess and mandibular deformity is considered a difficult problem in orthodontic and surgical treatment. This study used a navigation system for the correction of severe skeletal open bite in order to accurately transfer the virtual plan to the actual operation and achieve precise rigid internal fixation in bimaxillary osteotomies of the jaws. Twelve patients with a severe skeletal open bite associated with vertical maxillary excess and mandibular deformity were recruited...
September 19, 2018: International Journal of Oral and Maxillofacial Surgery
Kristie B Hadden, Connie L Arnold, Laura M Curtis, Jennifer M Gan, Scott Hur, Mary Kwasny, Jean C McSweeney, Latrina Y Prince, Michael S Wolf, Terry C Davis
Proper diabetes self-care requires patients to have considerable knowledge, a range of skills, and to sustain multiple health behaviors. Self-management interventions are needed that can be readily implemented and sustained in rural clinics with limited resources that disproportionately care for patients with limited literacy. Researchers on our team developed an evidence-based, patient-centered, low literacy intervention promoting diabetes self-care that includes: 1) the American College of Physicians (ACP) Diabetes Guide that uses plain language and descriptive photographs to teach core diabetes concepts and empower patients to initiate behavior change; 2) a brief counseling strategy to assist patients in developing short-term, explicit and attainable goals for behavior change ('action plans'); and 3) a training module for health coaches that prepares them to assume educator/counselor roles with the Diabetes Guide as a teaching tool...
September 19, 2018: Contemporary Clinical Trials
Tai-Hua Yang, Anne Gingery, Andrew R Thoreson, Dirk R Larson, Chunfeng Zhao, Peter C Amadio
BACKGROUND: Fibroblast behavior and cell-matrix interactions of cells from normal and idiopathic carpal tunnel syndrome (CTS) subsynovial connective tissue (SSCT) with and without Triamcinolone Acetonide (TA) were compared in this study. A cell-seeded gel contraction model was applied to investigate the effect of steroid treatment on SSCT fibroblast gene expression and function. METHODS: SSCT cells were obtained from CTS patients and fresh cadavers. Cells were isolated by mechanical and collagenase digestion...
September 22, 2018: BMC Musculoskeletal Disorders
Lynda K Beaupin, Megan E Pailler, Erin Brewer-Spritzer, Eric Kishel, Pei C Grant, Rachel M Depner, Kelly E Tenzek, Jennifer M Breier
No abstract text is available yet for this article.
September 22, 2018: Psycho-oncology
Audrey Gray
This image seeks to iteratively represent themes related to the availability of life-saving and life-threatening medications. The photograph also suggests the importance of several ethical questions.
September 1, 2018: AMA Journal of Ethics
Yee-Ling Wong, Charumathi Sabanayagam, Yang Ding, Chee-Wai Wong, Anna Chwee-Hong Yeo, Yin-Bun Cheung, Gemmy Cheung, Audrey Chia, Kyoko Ohno-Matsui, Tien-Yin Wong, Jie Jin Wang, Ching-Yu Cheng, Quan V Hoang, Ecosse Lamoureux, Seang-Mei Saw
Purpose: To determine the prevalence, risk factors, and impact of myopic macular degeneration (MMD) on visual impairment and functioning among adults in Singapore. Methods: A comprehensive eye examination, including subjective refraction, axial length, and visual acuity (VA) measurements, was performed in adults aged ≥40 years in the Singapore Epidemiology of Eye Diseases (SEED) study. From fundus photographs, MMD was graded using the International META-PM classification...
September 4, 2018: Investigative Ophthalmology & Visual Science
Philippe M Burlina, Neil Joshi, Katia D Pacheco, David E Freund, Jun Kong, Neil M Bressler
Importance: Although deep learning (DL) can identify the intermediate or advanced stages of age-related macular degeneration (AMD) as a binary yes or no, stratified gradings using the more granular Age-Related Eye Disease Study (AREDS) 9-step detailed severity scale for AMD provide more precise estimation of 5-year progression to advanced stages. The AREDS 9-step detailed scale's complexity and implementation solely with highly trained fundus photograph graders potentially hampered its clinical use, warranting development and use of an alternate AREDS simple scale, which although valuable, has less predictive ability...
September 14, 2018: JAMA Ophthalmology
Anna Alkozei, Monika Haack, Jeff Skalamera, Ryan Smith, Brieann C Satterfield, Adam C Raikes, William Ds Killgore
OBJECTIVES: Previous work suggests that sleep restriction (SR) reduces cognitive control and may increase negative implicit biases. Here we investigated whether SR might influence decision making on a social-evaluative task where individuals had to make judgments of threat based on facial photographs. Furthermore, we investigated the effect of changes in negative implicit biases as a result of sleep restriction on this decision-making task. DESIGN: Fourteen healthy adults underwent two 3-week counterbalanced in-laboratory stays (chronic SR and control sleep [CS] conditions)...
October 2018: Sleep Health
Chun-Yung Huang, Tien-Chou Wu, Yong-Han Hong, Shu-Ling Hsieh, Hui-Ru Guo, Ren-Han Huang
Gelatin has been broadly utilized in the food, pharmaceutical, photographic, cosmetic and packaging industries, and there is also huge potential for novel applications of gelatin in the fields of biotechnology and biomedicine. In the present study, we extracted gelatin from fish processing waste, i.e., scale of tilapia, by a combined method of extrusion-pretreatment and hot water extraction. The extrusion-pretreatment process increases the extraction yield of gelatin. Three gelatins (FS2: preconditioning with double-distilled water (ddH₂O) before extrusion; FS12: preconditioning with citric acid solution before extrusion; FS14: preconditioning with acetic acid solution before extrusion) were obtained and all of them enhanced cell adhesion, cell growth, and wound healing in HaCaT cells and protected HaCaT cells from H₂O₂-induced cellular damage...
September 20, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Bradley G Erskine
This paper presents a geologic and mineralogical investigation of asbestiform amphibole from blueschist in the Diablo Range, northern California. The analysis of fibers in air samples shows that the dominant blueschist amphibole composition ranges from glaucophane to winchite. In outcrop, blueschist amphibole exhibits a velvety luster, and its occurrence ranges from crosscutting veins to highly deformed foliated and lineated tectonites. TEM and SEM photographs reveal a highly fibrous habit typically associated with asbestiform amphiboles...
September 18, 2018: Toxicology and Applied Pharmacology
Apoorve Nayyar, Jihane Jadi, Roja Garimella, Stephen Tyler Elkins-Williams, Kristalyn K Gallagher, Loree K Kalliainen, Charles Scott Hultman, Cindy Wu
Background: Social media has become an indispensable tool for patients to learn about aesthetic surgery. Currently, procedure-specific patient preferences for social media platforms and content are unknown. Objectives: To evaluate social media preferences of patients seeking aesthetic surgery. Methods: We utilized a choice-based conjoint analysis survey to analyze the preferences of patients seeking three common aesthetic procedures - breast augmentation (BA), facial rejuvenation (FR) and combined breast/abdominal surgery (BAB)...
September 13, 2018: Aesthetic Surgery Journal
Alanna J Rebelo, Ben Somers, Karen J Esler, Patrick Meire
We provide reflectance spectra for 22 South African palmiet wetland species collected in spring 2015 from three wetlands throughout the Cape Floristic Region. In addition, we provide summarized plant functional trait data, as well as supporting and meta-data. Reflectance spectra were collected with a portable ASD Fieldspec Pro using standard methods. The 14 plant functional traits were measured on 10 replicates of each species, following standard protocols. We provide tables detailing these standard methods, as well a table with hypotheses on how these 14 continuous traits, as well as an additional 9 categorical traits, may affect ecosystem service provision...
October 2018: Data in Brief
Andrew Kelsey, Justin Finch
Lipoptena cervi , known as the deer ked, is an ectoparasite of cervids traditionally found in northern European countries such as Norway, Sweden, and Finland. Although rarely reported in the United States, this vector recently has been shown to carry Borrelia burgdorferi and Anaplasma phagocytophylum from specimens collected domestically. Importantly, it has been suggested that deer keds are one of the many disease-carrying vectors that are now found in more expansive regions of the world due to climate change...
August 2018: Cutis; Cutaneous Medicine for the Practitioner
Chen Xin, Yuwei Li, Xi Luo, Tianjia Shao, Jingyi Yu, Kun Zhou, Youyi Zheng
This paper presents a fully automatic framework for extracting editable 3D objects directly from a single photograph. Unlike previous methods which recover either depth maps, point clouds, or mesh surfaces, we aim to recover 3D objects with semantic parts and can be directly edited. We base our work on the assumption that most human-made objects are constituted by parts and these parts can be well represented by generalized primitives. Our work makes an attempt towards recovering two types of primitive-shaped objects, namely, generalized cuboids and generalized cylinders...
September 19, 2018: IEEE Transactions on Visualization and Computer Graphics
Susan B Bressler, Isoken Odia, Adam R Glassman, Ronald P Danis, Sandeep Grover, G Robert Hampton, Lee M Jampol, Maureen G Maguire, Michele Melia
PURPOSE: To explore 5-year changes from baseline in diabetic retinopathy severity among eyes treated with ranibizumab for diabetic macular edema. METHODS: Diabetic retinopathy severity was assessed from study visits and annual fundus photographs among participants in Protocol I ( The proportion of eyes that improved at annual examinations and the cumulative probability of worsening through 5 years were estimated. RESULTS: Among 235 participants with nonproliferative diabetic retinopathy at baseline, there were 29%, 28%, and 32% of eyes with retinopathy improvement at 1, 3, and 5 years, respectively...
September 18, 2018: Retina
Ching-Hsin Huang, Erick Chern, Jui-Hui Peng, Peter Hsien-Li Peng
BACKGROUND: The diffractive lens of the picosecond laser is relatively new, and there are few reports on its efficacy in treating atrophic acne scars, especially in Asian populations. OBJECTIVE: Evaluating the efficacy of diffractive lens 755-nm picosecond laser for atrophic acne scar treatment in Asians. PATIENTS AND METHODS: Forty-two patients who were treated for facial atrophic acne scars at a private dermatological clinic were enrolled in this retrospective analysis...
September 18, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Uyen Koh, Monika Janda, Joanne F Aitken, David L Duffy, Scott Menzies, Richard A Sturm, Helmut Schaider, Brigid Betz-Stablein, Tarl Prow, H Peter Soyer, Adele C Green
INTRODUCTION: Having many melanocytic naevi or 'moles' on the skin is the strongest predictor of melanoma; thus, much can be learnt from investigating naevi in the general population. We aim to improve the understanding of the epidemiology and biology of naevi by conducting a 3-year prospective study of melanocytic naevi in adults. METHODS AND ANALYSIS: This is a population-based cohort study of melanocytic naevi in 200 adults aged 20-69 years recruited via the Australian electoral roll...
September 19, 2018: BMJ Open
Theodore A Kung, Kelley M Kidwell, Kelly A Speth, Judy C Pang, Reshma Jagsi, Lisa A Newman, Edwin G Wilkins, Adeyiza O Momoh
BACKGROUND:  Delayed autologous breast reconstruction is commonly recommended in patients requiring postmastectomy radiation. This study examines gross and histologic changes in the breast skin of patients who have undergone postmastectomy radiation to help determine when radiation-induced skin changes begin to stabilize. METHODS:  A prospective pilot study was conducted on eight patients with invasive breast cancer who required mastectomy and radiotherapy. At the time of mastectomy and 2, 4, 6, 8, and 12 months after completion of radiotherapy, a punch biopsy was taken from the radiated mastectomy skin of each patient...
September 19, 2018: Journal of Reconstructive Microsurgery
Christopher A Barwacz, Clark M Stanford, Ursula A Diehl, Lyndon F Cooper, Jocelyne Feine, Michael McGuire, E Todd Scheyer
PURPOSE: To evaluate the influence that three different implant-abutment interface designs had on peri-implant mucosal outcomes as assessed by the pink esthetic score (PES) 3 years after delayed implant placement and immediate provisionalization. MATERIALS AND METHODS: Adult subjects (n = 141) requiring replacement of a bounded single tooth in the anterior maxilla as well as first premolar sites were randomized to receive one of three unique implant-abutment interface designs (conical interface [CI]; flat-to-flat interface [FI]; or platform-switch interface [PS])...
September 2018: International Journal of Oral & Maxillofacial Implants
João César Zielak, David Gulin Neto, Makeli Aparecida Cazella Zielak, Leonardo Brunet Savaris, Fernando Luis Esteban Florez, Tatiana Miranda Deliberador
Background: Novel multifunctional biomaterials were recently designed to allow for an optimized tissue regeneration process. Purpose: To comprehensively assess (photographic, radiographic and histological) the in vivo functionality of demineralized bovine bone matrix (DBM) associated with an experimental marine organic extract (MOE) from nacre in a sheep ectopic grafting model. Materials and methods: Synthesis of MOE was based on mixing powdered nacre (0...
September 2018: Heliyon
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