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https://www.readbyqxmd.com/read/28636122/hidradenitis-suppurativa-in-down-syndrome-a-case-series
#1
Issam Hamadah, Mansoor Haider, Muzamil Chisti, Yousef Binamer
BACKGROUND/OBJECTIVES: Many dermatologic and systemic diseases have been reported in association with hidradenitis suppurativa, but its association with Down syndrome is rarely mentioned in the literature. The objective of the current study was to assess the frequency of hidradenitis suppurativa in patients with Down syndrome who visited our clinic over 4 years. METHODS: We recorded the presenting complaints and dermatologic problems of patients with Down syndrome who visited our clinic from January 2011 to December 2014...
June 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28635138/snake-spectacle-vessel-permeability-to-sodium-fluorescein
#2
Roy W Bellhorn, Ann R Strom, Monica J Motta, John Doval, Michelle G Hawkins, Joanne Paul-Murphy
OBJECTIVE: Assess vascular permeability of the snake spectacle to sodium fluorescein during resting and shedding phases of the ecdysis cycle. ANIMAL STUDIED: Ball python (Python regius). PROCEDURES: The snake was anesthetized, and spectral domain optic coherence tomography was performed prior to angiographic procedures. An electronically controlled digital single-lens reflex camera with a dual-head flash equipped with filters suitable for fluorescein angiography was used to make images...
June 20, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28634154/improving-consensus-scoring-of-crowdsourced-data-using-the-rasch-model-development-and-refinement-of-a-diagnostic-instrument
#3
Christopher John Brady, Lucy Iluka Mudie, Xueyang Wang, Eliseo Guallar, David Steven Friedman
BACKGROUND: Diabetic retinopathy (DR) is a leading cause of vision loss in working age individuals worldwide. While screening is effective and cost effective, it remains underutilized, and novel methods are needed to increase detection of DR. This clinical validation study compared diagnostic gradings of retinal fundus photographs provided by volunteers on the Amazon Mechanical Turk (AMT) crowdsourcing marketplace with expert-provided gold-standard grading and explored whether determination of the consensus of crowdsourced classifications could be improved beyond a simple majority vote (MV) using regression methods...
June 20, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28633153/association-between-visual-function-and-subretinal-drusenoid-deposits-in-normal-and-early-age-related-macular-degeneration-eyes
#4
David Neely, Anna V Zarubina, Mark E Clark, Carrie E Huisingh, Gregory R Jackson, Yuhua Zhang, Gerald McGwin, Christine A Curcio, Cynthia Owsley
PURPOSE: To examine the association between subretinal drusenoid deposits (SDDs) identified by multimodal retinal imaging and visual function in older eyes with normal macular health or in the earliest phases of age-related macular degeneration (AMD). METHODS: Age-related macular degeneration status for each eye was defined according to the Age-Related Eye Disease Study (AREDS) 9-step classification system (normal = Step 1, early AMD = Steps 2-4) based on color fundus photographs...
July 2017: Retina
https://www.readbyqxmd.com/read/28632764/accuracy-and-reliability-of-retinal-photo-grading-for-diabetic-retinopathy-remote-graders-from-a-developing-country-and-standard-retinal-photo-grader-in-australia
#5
Fakir M Amirul Islam
BACKGROUND: To evaluate the accuracy and reliability of fundus retinal photos graded by local graders in Bangladesh with those graded by an expert at the Centre for Eye Research Australia (CERA) in the context of mass scale diabetic retinopathy (DR) screening in Bangladesh. METHODS: A population-based cross-sectional study of 3,104 adults identified 213 (7.2%) eligible patients with diabetes of age ≥ 40 years in 2012-2013. Retinal photographs were collected using a non-mydriatic digital fundus retinal camera and a two-field imaging protocol...
2017: PloS One
https://www.readbyqxmd.com/read/28630728/parameters-for-assessment-of-the-inferior-acetabulum-morphology-in-300-adult-hips
#6
Munif A Hatem, Luiz A M da Cunha, João C M Abdo, Hal David Martin
The inferior acetabulum (IA) has been studied as a stabilizer of the hip in flexed positions with potential implications in femoroacetabular impingement and hip instability. However, there is a paucity of studies considering the normal morphology and parameters for assessment of the IA. The purpose of this study was to define parameters to assess the IA morphology and their normal range. Specifically, the objectives were to assess: (i) the width of the anterior horn (AH) and posterior horn (PH) of the acetabulum; (ii) the inclination of the articular surface of the AH angle (AHA) and PH angle (PHA) in the axial plane; (iii) the anterior opening angle of the IA and differences between genders...
January 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/28630374/classifying-the-body-in-marlene-dumas-the-image-as-burden
#7
Anthea Gordon
Medical photography, and in particular dermatological imagery, is often assumed to provide an objective, and functional, representation of disease and that it can act as a diagnostic aid. By contrast, artistic conceptions of the images of the body tend to focus on interpretative heterogeneity and ambiguity, aiming to create or explore meaning rather than enact a particular function. In her 2015 retrospective exhibition at the Tate Modern, South African artist Marlene Dumas questions these disciplinary divides by using medical imagery (among other photographic sources) as the basis for her portraits...
June 19, 2017: Medical Humanities
https://www.readbyqxmd.com/read/28630050/effectiveness-of-computer-aided-diagnosis-cadx-of-breast-pathology-using-immunohistochemistry-results-of-core-needle-biopsy-samples-for-synaptophysin-oestrogen-receptor-and-ck14-p63-for-classification-of-epithelial-proliferative-lesions-of-the-breast
#8
Ichiro Maeda, Manabu Kubota, Jiro Ohta, Kimika Shinno, Shinya Tajima, Yasushi Ariizumi, Masatomo Doi, Yoshiyasu Oana, Yoshihide Kanemaki, Koichiro Tsugawa, Takahiko Ueno, Masayuki Takagi
AIMS: The aim of this study was to develop a computer-aided diagnosis (CADx) system for identifying breast pathology. METHODS: Two sets of 100 consecutive core needle biopsy (CNB) specimens were collected for test and validation studies. All 200 CNB specimens were stained with antibodies targeting oestrogen receptor (ER), synaptophysin and CK14/p63. All stained slides were scanned in a whole-slide imaging system and photographed. The photographs were analysed using software to identify the proportions of tumour cells that were positive and negative for each marker...
June 19, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28629819/umbilical-appearance-and-patient-parent-satisfaction-over-5years-of-follow-up-after-umbilical-hernia-repair-in-children
#9
Masahiro Zenitani, Takashi Sasaki, Natsumi Tanaka, Takaharu Oue
BACKGROUND/PURPOSE: We evaluated the long-term umbilical appearance and patient/parent satisfaction at follow-up after umbilical hernia repair (UHR). METHODS: In a retrospective review of 128 children who underwent UHR and were followed up for more than 5years, satisfaction was assessed using e-mailed questionnaires and attached photographs of the umbilicus. RESULTS: The survey response rate was 80.3% by parents, 79.5% by patients, and 72...
June 11, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28628684/megasessions-efficacy-of-fewer-longer-treatment-sessions-for-fat-reduction-in-noninvasive-body-contouring-using-a-radiofrequency-based-device
#10
Diane Duncan
<p>While the field of noninvasive body contouring is booming, many patients still note a lesser result than they might achieve with a single session of liposuction or dermolipectomy. The duration of a noninvasive fat reduction treatment series can be daunting. Patients have questioned the worth of these procedures when the expected benefit is modest and the time they devote to the project is significant. An eight-patient mini-study was performed to see if two or three "megasessions" could be substituted for eight weekly sessions of bipolar radiofrequency based fat reduction treatments...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28626865/positional-changes-of-maxillary-central-incisors-following-orthodontic-treatment-using-single-crown-implants-as-fixed-reference-markers
#11
E B Brahem, B Holm, L Sonnesen, N Worsaae, K Gotfredsen
OBJECTIVES: This follow-up study (1) compares tooth displacement of central incisors in patients with and without pre-implant orthodontic treatment and (2) investigates whether sex, age, or orthodontic retention have an effect on tooth displacement after the insertion of single-crown implants. MATERIALS AND METHODS: Fifty-seven patients - thirty-seven with (test group) and twenty without pre-implant orthodontic treatment (control group) - were rehabilitated with 89 single-crown implants in the upper maxilla...
June 18, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28626631/chronic-eosinophilic-pneumonia-adjunctive-therapy-with-inhaled-steroids
#12
Christopher Chan, David DeLapp, Perry Nystrom
Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare form of diffuse parenchymal lung disease first identified by Carrington et al. in 1969. It is characterized by the presence of constitutional and respiratory symptoms with associated peripheral opacities on imaging and elevated serum and/or bronchoalveolar eosinophilia. Although data is limited regarding etiology or prevalence, it is known that ICEP has a 2:1 female: male predominance and typically affects non-smokers. Diagnosis rests on the clinical constellation of respiratory symptoms of at least 2-4 weeks duration, the presence of diffuse pulmonary alveolar consolidation, classically described as the "photographic negative of pulmonary edema", the presence of eosinophils ≥40% on bronchoalveolar lavage or ≥1000/mm(3) eosinophils on peripheral blood and the exclusion of other known causes of eosinophilic lung diseases such as drugs, toxins, fungi, parasites, and collagen-vascular disorders...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28626432/visible-social-interactions-do-not-support-the-development-of-false-belief-understanding-in-the-absence-of-linguistic-input-evidence-from-deaf-adult-homesigners
#13
Deanna L Gagne, Marie Coppola
Congenitally deaf individuals exhibit enhanced visuospatial abilities relative to normally hearing individuals. An early example is the increased sensitivity of deaf signers to stimuli in the visual periphery (Neville and Lawson, 1987a). While these enhancements are robust and extend across a number of visual and spatial skills, they seem not to extend to other domains which could potentially build on these enhancements. For example, congenitally deaf children, in the absence of adequate language exposure and acquisition, do not develop typical social cognition skills as measured by traditional Theory of Mind tasks...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28625853/photoelicitation-a-useful-tool-to-investigate-management-of-the-vulnerability-of-homeless-women
#14
Cristina Oter-Quintana, Teresa González-Gil, Ángel Martín-García, María Teresa Alcolea-Cosín
AIMS: The proposal of the manuscript is to provide a methodological reflection on the use of photo-elicitation as a data gathering strategy to explore vulnerability management among homeless women. METHODS: A grounded theory study was carried out. Photo elicitation was one of the data gathering techniques used between February 2015 and February 2017. Five women were selected through intentional sampling. All of them were over 18 years old and residents in 4 shelters within the Madrid Care for the Homeless network...
June 15, 2017: Enfermería Clínica
https://www.readbyqxmd.com/read/28625113/men-with-a-terminal-illness-relax-their-criteria-for-facial-attractiveness
#15
Dariusz P Danel, Agnieszka E Siennicka, Pawel Fedurek, Tomasz Frackowiak, Piotr Sorokowski, Ewa A Jankowska, Boguslaw Pawlowski
According to the life history paradigm, in life-threatening conditions, sexual selection criteria are relaxed in order to increase the probability of a last resort reproduction, ultimately contributing to reproductive success. This should be reflected in loosened mating preferences - a process observed in nonhuman animals. Studies investigating this aspect in humans, however, are scarce. This study explored the aesthetic preferences towards facial and nonfacial stimuli in terminally ill patients with heart failure (HF) and their healthy, same-sex peers...
July 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/28623421/comparison-of-dual-energy-ct-ultrasound-and-surface-measurement-for-assessing-tophus-dissolution-during-rapid-urate-debulking
#16
Dodji V Modjinou, Svetlana Krasnokutsky, Soterios Gyftopoulos, Virginia C Pike, Elaine Karis, Robert T Keenan, Kristen Lee, Daria B Crittenden, Jonathan Samuels, Michael H Pillinger
Tophaceous gout is painful and impairs quality of life. The optimal modality for assessing tophus resolution in response to urate-lowering treatment remains poorly defined. Using pegloticase as a model system for resolving tophi, we compared multiple imaging and physical diagnostic strategies for assessing tophus resolution. A 32-year-old subject with chronic refractory tophaceous gout was enrolled and received 6 months of pegloticase treatment. Measurements of tophi using vernier calipers (monthly), photographs and musculoskeletal ultrasound (MSK-US; every 3 months), and dual-energy CT (DECT) were compared...
June 16, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28623387/retinal-vascular-geometry-and-6%C3%A2-year-incidence-and-progression-of-diabetic-retinopathy
#17
Carol Yim-Lui Cheung, Charumathi Sabanayagam, Antony Kwan-Pui Law, Neelam Kumari, Daniel Shu-Wei Ting, Gavin Tan, Paul Mitchell, Ching Yu Cheng, Tien Yin Wong
AIMS/HYPOTHESIS: We aimed to examine prospectively the association between a range of retinal vascular geometric variables measured from retinal photographs and the 6 year incidence and progression of diabetic retinopathy. METHODS: We conducted a prospective, population-based cohort study of Asian Malay individuals aged 40-80 years at baseline (n = 3280) who returned for a 6 year follow-up. Retinal vascular geometric variables (tortuosity, branching, fractal dimension, calibre) were measured from baseline retinal photographs using a computer-assisted program (Singapore I Vessel Assessment)...
June 16, 2017: Diabetologia
https://www.readbyqxmd.com/read/28622667/netvlad-cnn-architecture-for-weakly-supervised-place-recognition
#18
Relja Arandjelovic, Petr Gronat, Akihiko Torii, Tomas Pajdla, Josef Sivic
We tackle the problem of large scale visual place recognition, where the task is to quickly and accurately recognize the location of a given query photograph. We present the following four principal contributions. First, we develop a convolutional neural network (CNN) architecture that is trainable in an end-to-end manner directly for the place recognition task. The main component of this architecture, NetVLAD, is a new generalized VLAD layer, inspired by the "Vector of Locally Aggregated Descriptors" image representation commonly used in image retrieval...
June 1, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28622325/fingerprick-autologous-blood-a-novel-treatment-for-dry-eye-syndrome
#19
J Than, S Balal, J Wawrzynski, N Nesaratnam, G M Saleh, J Moore, A Patel, S Shah, B Sharma, B Kumar, J Smith, A Sharma
PurposeDry eye syndrome (DES) causes significant morbidity. Trials of blood-derived products in treatment of the condition show promising results. However, their production is expensive and time-consuming. We investigate fingerprick autologous blood (FAB) as an alternative low-cost, readily accessible treatment for DES.Patients and methodsProspective, non-comparative, interventional case series. In total, 29 eyes of 16 DES patients (2 males and 14 females) from two NHS sites in the United Kingdom. Patients instructed to clean a finger, prick with a blood lancet, and apply a drop of blood to the lower fornix of the affected eye(s), 4 times daily for 8 weeks then stop and review 4 weeks later...
June 16, 2017: Eye
https://www.readbyqxmd.com/read/28621489/validation-and-comparison-of-quality-of-life-measures-for-topical-5-fluorouracil-treatment-results-from-a-randomized-controlled-trial
#20
H Pomerantz, M-M Chren, R Lew, M A Weinstock
BACKGROUND: Topical 5-fluorouracil (5-FU) is commonly used for high-risk patients with keratinocyte carcinoma (KC). Skindex and Skin Cancer Index (SCI) are validated instruments to measure quality of life (QoL) of patients with KC and those who have had surgical treatment of KCs. AIM: To validate Skindex and SCI for topical 5-fluorouracil (5-FU) application and to compare the two QoL instruments. METHODS: We randomized 932 veterans at high risk for developing a KC to either topical 5-FU or vehicle control cream applied to the face and ears for up to 1 month...
July 2017: Clinical and Experimental Dermatology
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