keyword
MENU ▼
Read by QxMD icon Read
search

Bla

keyword
https://www.readbyqxmd.com/read/28225710/chronic-stress-exacerbates-neuropathic-pain-via-the-integration-of-stress-affect-related-information-with-nociceptive-information-in-the-central-nucleus-of-the-amygdala
#1
Ming-Jia Li, Ling-Yu Liu, Lin Chen, Jie Cai, You Wan, Guo-Gang Xing
Exacerbation of pain by chronic stress and co-morbidity of pain with stress-related psychiatric disorders including anxiety and depression, represent significant clinical challenges. However, the underlying mechanisms still remain unclear. Here, we investigated whether chronic forced swim (FS) stress-induced exacerbation of neuropathic pain is mediated by the integration of stress-affect related information with nociceptive information in the central nucleus of the amygdala (CeA). We first demonstrated that chronic FS stress (CFSS) indeed produces both depressive-like behaviors and exacerbation of spared nerve injury (SNI)-induced mechanical allodynia in rats...
December 29, 2016: Pain
https://www.readbyqxmd.com/read/28222579/effects-of-a-small-sided-game-based-training-programme-on-repeated-sprint-and-change-of-direction-abilities-in-recreationally-trained-football-players
#2
Pascual Bujalance-Moreno, Felipe García-Pinillos, Pedro Á Latorre-Román
BACKGROUND: To examine the effects of 6-week periodized small-sided game (SSG) training intervention on change of direction [COD], sprint and repeated sprint ability [RSA] in recreational male football players. METHODS: Twenty-three young football players (age: 20.86 years) were randomized in a control group (n = 11) and an experimental group (n = 12). The SSG programme was included in the experimental group's training sessions. The players completed two variations of a SSG (i...
February 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28221080/blockade-of-glutamatergic-transmission-in-the-primate-basolateral-amygdala-suppresses-active-behavior-without-altering-social-interaction
#3
Patrick A Forcelli, Laurie L Wellman, Ludise Malkova
The amygdala is an integrator of affective processing, and a key component of a network regulating social behavior. While decades of lesion studies in nonhuman primates have shown alterations in social interactions after amygdala damage, acute manipulations of the amygdala in primates have been underexplored. We recently reported (Wellman, Forcelli, Aguilar, & Malkova, 2016) that acute pharmacological inhibition of the basolateral complex of the amygdala (BLA) or the central nucleus of the amygdala increased affiliative social interactions in experimental dyads of macaques; this was achieved through microinjection of a GABA-A receptor agonist...
February 20, 2017: Behavioral Neuroscience
https://www.readbyqxmd.com/read/28221079/cue-induced-food-seeking-after-punishment-is-associated-with-increased-fos-expression-in-the-lateral-hypothalamus-and-basolateral-and-medial-amygdala
#4
Erin J Campbell, David J Barker, Helen M Nasser, Konstantin Kaganovsky, Christopher V Dayas, Nathan J Marchant
In humans, relapse to unhealthy eating habits following dieting is a significant impediment to obesity treatment. Food-associated cues are one of the main triggers of relapse to unhealthy eating during self-imposed abstinence. Here we report a behavioral method examining cue-induced relapse to food seeking following punishment-induced suppression of food taking. We trained male rats to lever press for food pellets that were delivered after a 10-s conditional stimulus (CS) (appetitive). Following training, 25% of reinforced lever presses resulted in the presentation of a compound stimulus consisting of a novel CS (aversive) and the appetitive CS followed by a pellet and footshock...
February 20, 2017: Behavioral Neuroscience
https://www.readbyqxmd.com/read/28213154/density-and-neurochemical-profiles-of-neuronal-nitric-oxide-synthase-expressing-interneuron-in-the-mouse-basolateral-amygdala
#5
Xiaona Wang, Chunhua Liu, Xiaochen Wang, Fei Gao, Ren-Zhi Zhan
Neuronal nitric oxide synthase (nNOS)-expressing interneurons reside in the basolateral nucleus of the amygdala (BLA) of rodents. In the present study, we immunohistochemically analyzed nNOS-positive cells in the mouse BLA by focusing on their density, γ-Aminobutyric acid (GABA)ergicity, and co-localization with calcium-binding proteins and neuropeptides. The density of nNOS-containing neurons was analyzed with unbiased stereology. Experiments were conducted in both adult wild-type C57BL/6 and glutamic acid decarboxylase-green fluorescence protein (GAD67-GFP) knock-in mice, in which GFP is expressed in GABAergic neurons under the control of the endogenous GAD67 gene promoter...
February 14, 2017: Brain Research
https://www.readbyqxmd.com/read/28212941/injections-of-the-of-the-%C3%AE-1-adrenoceptor-antagonist-prazosin-into-the-median-raphe-nucleus-increase-food-intake-and-fos-expression-in-orexin-neurons-of-free-feeding-rats
#6
Eduardo Simão da Silva, Rafael Appel Flores, Anderson Savaris Ribas, Ana Paula Taschetto, Moacir Serralvo Faria, Leandro Bueno Lima, Martin Metzger, José Donato, Marta Aparecida Paschoalini
Previously, we showed that the blockade of α1-adrenoreceptors in the median raphe nucleus (MnR) increased food intake in free-feeding rats, indicating that adrenergic mechanisms in the MnR participate in the regulation of food intake. However, the impact of such a pharmacological manipulation on other neural circuits related to food intake remains unknown. In the current study, we sought to identify forebrain regions which are responsive to α1-adrenergic receptor blockade and presumably involved in the modulation of the feeding response...
February 14, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28199723/brief-optogenetic-inhibition-of-the-basolateral-amygdala-bla-in-mice-alters-effects-of-stressful-experiences-on-rapid-eye-movement-sleep-rem
#7
Mayumi Machida, Laurie L Wellman, Mairen E Fitzpatrick, Olga Hallum, Amy M Sutton, György Lonart, Larry D Sanford
No abstract text is available yet for this article.
February 10, 2017: Sleep
https://www.readbyqxmd.com/read/28197140/molecular-characteristics-of-carbapenem-resistant-enterobacter-cloacae-in-ningxia-province-china
#8
Zhiyun Shi, Huizheng Zhao, Gang Li, Wei Jia
The emergence of carbapenem-resistant Enterobacteriaceae (CRE) has become a major public health concern worldwide and a new challenge in the treatment of infectious diseases. The molecular characteristics of Enterobacter cloacae in Ningxia China are unknown. In this study, we reported 10 carbapenem-resistant E. cloacae isolates from the General Hospital of Ningxia Medical University, the largest university hospital in Ningxia between January 2012 and December 2013. Bacteria isolates were identified by Vitek2 compact and the identity of non-duplicate E...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28196500/monitoring-training-response-in-young-friesian-dressage-horses-using-two-different-standardised-exercise-tests-sets
#9
Cornelis Marinus de Bruijn, Willem Houterman, Margreet Ploeg, Bart Ducro, Berit Boshuizen, Klaartje Goethals, Elisabeth-Lidwien Verdegaal, Catherine Delesalle
BACKGROUND: Most Friesian horses reach their anaerobic threshold during a standardized exercise test (SET) which requires lower intensity exercise than daily routine training. AIM: to study strengths and weaknesses of an alternative SET-protocol. Two different SETs (SETA and SETB) were applied during a 2 month training period of 9 young Friesian dressage horses. SETB alternated short episodes of canter with trot and walk, lacking long episodes of cantering, as applied in SETA...
February 14, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28193691/optogenetic-examination-of-prefrontal-amygdala-synaptic-development
#10
Maithe Arruda-Carvalho, Wan-Chen Wu, Kirstie A Cummings, Roger L Clem
A brain network comprising the medial prefrontal cortex (mPFC) and amygdala plays important roles in developmentally-regulated cognitive and emotional processes. However, very little is known about the maturation of mPFC-amygdala circuitry. We conducted anatomical tracing of mPFC projections and optogenetic interrogation of their synaptic connections with neurons in the basolateral amygdala (BLA) at neonatal to adult developmental stages in mice. Results indicate that mPFC-BLA projections exhibit delayed emergence relative to other mPFC pathways and establish synaptic transmission with BLA excitatory and inhibitory neurons in late infancy, events which coincide with a massive increase in overall synaptic drive...
February 13, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28179011/cardiorespiratory-and-metabolic-responses-to-body-mass-based-squat-exercise-in-young-men
#11
Miki Haramura, Yohei Takai, Takaya Yoshimoto, Masayoshi Yamamoto, Hiroaki Kanehisa
BACKGROUND: The purpose of this study was to quantify cardiorespiratory and metabolic responses to body mass-based squat exercise, with specific emphasis on the relationships with the exercise duration. METHODS: Fifteen healthy young men performed body mass-based squat exercise as well as an incremental loaded bicycle test, which determine maximal oxygen uptake and maximal heart rate, with an interval of 2 days between the tests. During both tasks, oxygen uptake, blood lactate concentration (BLa), and heart rate (HR) were determined...
February 8, 2017: Journal of Physiological Anthropology
https://www.readbyqxmd.com/read/28178514/projection-target-defined-effects-of-orexin-and-dynorphin-on-vta-dopamine-neurons
#12
Corey Baimel, Benjamin K Lau, Min Qiao, Stephanie L Borgland
Circuit-specific signaling of ventral tegmental area (VTA) dopamine neurons drives different aspects of motivated behavior, but the neuromodulatory control of these circuits is unclear. We tested the actions of co-expressed lateral hypothalamic peptides, orexin A (oxA) and dynorphin (dyn), on projection-target-defined dopamine neurons in mice. We determined that VTA dopamine neurons that project to the nucleus accumbens lateral shell (lAcbSh), medial shell (mAcbSh), and basolateral amygdala (BLA) are largely non-overlapping cell populations with different electrophysiological properties...
February 7, 2017: Cell Reports
https://www.readbyqxmd.com/read/28167453/the-role-of-%C3%AE-arrestin-2-on-fear-anxious-related-memory-in-a-rat-model-of-post-traumatic-stress-disorder
#13
Jinlan Ding, Fang Han, Lili Wen, Bing Xiao, Yuxiu Shi
BACKGROUND: Post-traumatic stress disorder (PTSD) can be categorised as a disorder of dysregulated fear processing. In the formation and development of PTSD, whether fear/anxious-related memory is regulated by β-arrestin-2, and happened along the signal transduction pathways remains unknown. METHOD: We used single prolonged stress (SPS) as the animal model of PTSD. Next, elevated plus maze tests (EPM) was performed to examine fear/anxious memory- related behaviors...
January 17, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28166680/opposing-roles-of-b-lymphocyte-subsets-in-atherosclerosis
#14
Tin Kyaw, Peter Tipping, Alex Bobik, Ban-Hock Toh
Atherosclerosis is initiated by cholesterol entry into arteries that triggers chronic immune-inflammatory lesions in the vessels. Early lesions are clinically insignificant but advanced complex lesions and vulnerable rupture prone lesions impact on quality of life and can be life threatening. Rupture of vulnerable atherosclerotic lesions initiates thrombotic occlusion of vital arteries precipitating heart attacks and strokes that remain major killers globally despite therapeutic use of statins to lower blood cholesterol levels...
February 2017: Autoimmunity
https://www.readbyqxmd.com/read/28163104/age-dependent-regulation-of-gaba-transmission-by-kappa-opioid-receptors-in-the-basolateral-amygdala-of-sprague-dawley-rats
#15
K R Przybysz, D F Werner, M R Diaz
Anxiety disorders are one of the most common and debilitating mental illnesses worldwide. Growing evidence indicates an age-dependent rise in the incidence of anxiety disorders from adolescence through adulthood, suggestive of underlying neurodevelopmental mechanisms. Kappa opioid receptors (KORs) are known to contribute to the development and expression of anxiety; however, the functional role of KORs in the basolateral amygdala (BLA), a brain structure critical in mediating anxiety, particularly across ontogeny, are unknown...
February 3, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28150086/morphological-structural-and-functional-alterations-of-the-prefrontal-cortex-and-the-basolateral-amygdala-after-early-lesion-of-the-rat-mediodorsal-thalamus
#16
Zakaria Ouhaz, Saadia Ba-M'hamed, Mohamed Bennis
Early postnatal damage to the mediodorsal thalamus (MD) produces deficits in cognition and behavior believed to be associated with early prefrontal cortical maldevelopment. We assessed the role of MD afferents during development on the morphological and functional maturation of the prefrontal cortex (PFC) and the basolateral amygdala (BLA). Sprague-Dawley rat pups (n = 56) received a bilateral electrolytic lesion of the MD or a MD Sham lesion on postnatal day 4. 7 weeks later, all rats were tested in anxiety-related and cognitive paradigms using the elevated plus maze and novel object recognition tests...
February 1, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28145981/the-anxiolytic-like-effect-of-rutin-in-rats-involves-gabaa-receptors-in-the-basolateral-amygdala
#17
Alberto Hernandez-Leon, María E González-Trujano, Alonso Fernández-Guasti
Rutin is a bioflavonoid found in medicinal plants used to reduce anxiety. Evidence is lacking of rutin's anxiolytic-like activity, putative mechanism(s) of action, and neural sites of effects. The basolateral amygdala (BLA) is the main brain region that regulates anxiety, through GABAA/benzodiazepine (BDZ) receptors, which are modulated by flavonoids. Therefore, the main aim of this study was to investigate whether the anxiolytic-like effect of rutin involves GABAA/BDZ receptors in the BLA. Rutin was administered systemically (30-1000 mg/kg, intraperitoneal) or microinjected into the BLA (16 nmol/4 µl, intracerebral), and its effects were assessed in the elevated plus-maze and open-field tests...
January 31, 2017: Behavioural Pharmacology
https://www.readbyqxmd.com/read/28144604/evaluation-of-metallo-%C3%AE-lactamase-production-and-carriage-of-bla-vim-genes-in-pseudomonas-aeruginosa-isolated-from-burn-wound-infections-in-isfahan
#18
Mahmood Saffari, Farzaneh Firoozeh, Mohammad Pourbabaee, Mohammad Zibaei
BACKGROUND: Metallo-β-lactamase-production among Gram-negative bacteria, including Pseudomonas aeruginosa, has become a challenge for treatment of infections due to these resistant bacteria. OBJECTIVES: The aim of the current study was to evaluate the metallo-β-lactamase-production and carriage of bla-VIM genes among carbapenem-resistant P. aeruginosa isolated from burn wound infections. PATIENTS AND METHODS: A cross-sectional study was conducted from September 2014 to July 2015...
December 2016: Archives of Trauma Research
https://www.readbyqxmd.com/read/28135225/the-metabolic-and-mechanical-effects-of-laddermill-graded-exercise-testing
#19
Timothy D Allerton, Conrad P Earnest, Neil M Johannsen
The purpose of this study was to compare the metabolic responses and mechanical impact forces during a maximal graded exercise test (GXT) on a Laddermill (LM) versus a standard treadmill (TM). Twenty college-aged men (n=10) and women completed a GXT on the TM and LM in random order. During the GXT, expired gases (VO2 and VCO2), HR, accelerometer data, blood lactate (BLa) and rating of perceived exertion (RPE) were collected in the last minute of each stage. Data were analyzed by paired t-tests and presented herein as mean ± SD...
January 20, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28131899/blockade-of-intracellular-zn-2-signaling-in-the-basolateral-amygdala-affects-object-recognition-memory-via-attenuation-of-dentate-gyrus-ltp
#20
Yuki Fujise, Mitsuyasu Kubota, Miki Suzuki, Haruna Tamano, Atsushi Takeda
Hippocampus-dependent memory is modulated by the amygdala. However, it is unknown whether intracellular Zn(2+) signaling in the amygdala is involved in hippocampus-dependent memory. On the basis of the evidence that intracellular Zn(2+) signaling in dentate granule cells (DGC) is necessary for object recognition memory via LTP at medial perforant pathway (PP)-DGC synapses, the present study examined whether intracellular Zn(2+) signaling in the amygdala influences object recognition memory via modulation of LTP at medial PP-DGC synapses...
January 25, 2017: Neurochemistry International
keyword
keyword
108376
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"