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Varicella zoster complications

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https://www.readbyqxmd.com/read/28905216/slowly-progressing-varicella-zoster-brainstem-encephalitis-complicating-ramsay-hunt-syndrome-in-an-immunocompetent-patient-case-report-and-review-of-the-literature
#1
Vito A G Ricigliano, Lorenzo Saraceno, Michele Cavalli, Mariaemma Rodegher, Giovanni Meola
A 56-year-old immunocompetent male developed brainstem encephalitis complicating Ramsay Hunt syndrome. The disease had a slowly progressing course of months after the triggering infection, much longer than previously reported. Furthermore, magnetic resonance imaging, physical-chemical, and cell count analyses on cerebrospinal fluid were normal, whereas polymerase chain reaction for varicella zoster virus DNA was positive. The simultaneous negativity of both imaging and basic CSF exams is very rare, although possible event which confirms the irreplaceable role of viral screening on CSF...
September 13, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28900551/appendicitis-caused-by-primary-varicella-zoster-virus-infection-in-a-child-with-digeorge-syndrome
#2
Lotte Møller Smedegaard, Claus Bohn Christiansen, Linea Cecilie Melchior, Anja Poulsen
INTRODUCTION: Chickenpox is caused by varicella zoster virus (VZV). Although predominantly a mild disease, it can cause considerable morbidity and in rare occasions even mortality in healthy children as well as increased morbidity and mortality in immunocompromised patients. The aetiology of appendicitis is largely unknown but is thought to be multifactorial. Appendicitis is a suspected, but not well documented, complication from varicella zoster virus infection. CASE PRESENTATION: A five-year-old girl diagnosed with DiGeorge syndrome and a prolonged primary VZV infection was admitted due to abdominal pain, increasing diarrhoea, vomiting, and poor general condition...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/28895088/prevalence-of-a-history-of-prior-varicella-herpes-zoster-infection-in-multiple-sclerosis
#3
Ali Manouchehrinia, Radu Tanasescu, Huner Kareem, Oltita P Jerca, Fouzia Jabeen, Rachelle Shafei, Judith Breuer, Keith Neal, William Irving, Cris S Constantinescu
Varicella zoster virus (VZV) infection has been implicated in multiple sclerosis (MS), but direct causal involvement has been disputed. Nevertheless, knowledge of VZV exposure is important, given the risk of serious complications of first exposure while undergoing immunosuppressive treatment, in particular with fingolimod. We distributed questionnaires to MS clinic patients, requesting information about history of chickenpox, sibling/household/occupational exposure, history of zoster (shingles), and disease-modifying treatment...
September 11, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28839425/ramsay-hunt-syndrome-a-diagnostic-challenge-for-general-dental-practitioners
#4
Gautham Singh, V Subhalakshmi, S Balasubramanian, Madhvika Patidar, Kranti Kiran Reddy Ealla
Ramsay hunt syndrome is not just a syndrome but it's rather an infectious disease caused by reactivation of latent varicella-zoster virus in geniculate ganglion. This was first explained by J. Ramsay Hunt as a triad of complications like otalgia, mucosal and cutaneous rashes with or without trigeminal facial palsy. The facial palsy can occur with characteristic vesicles along the path of nerve. We present a case of Ramsay Hunt syndrome in a 48-year-old male. The unilateral pattern of facial involvement and presence of vesicles assisted us for early diagnosis, distinguishing the syndrome with diseases mimicking other severe neurological illnesses and prompt treatment...
April 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28834054/herpesviruses-excretion-in-saliva-of-pediatric-transplant-recipients
#5
Consuelo Beatriz Correa Sierra, Vivian Kourí Cardellá, Lissette Pérez Santos, Cesar E Silverio, Norma Hondal, Jose Florin
BACKGROUND: Saliva samples could be used for follow-up of herpesviruses infection in the pediatric transplant recipients. OBJECTIVE: With the aim of determining the frequency of herpesviral infections in saliva samples after transplantation, and the association with viremia and complications, a pilot longitudinal follow-up of pediatric Cuban transplanted recipients (kidney and liver) was performed. METHODS: Quantitative real-time polymerase chain reaction of cytomegalovirus (CMV), Epstein-Barr virus, herpes simplex virus, human herpesevirus-6 (HHV6), varicella zoster virus, and human herpesvirus-8 were serially assayed in saliva and serum samples from 27 transplanted patients, during 32 weeks after the graft...
August 21, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28830902/zoster-vaccine-associated-primary-varicella-infection-in-an-immunocompetent-host
#6
Kaoru Harada, Henry Heaton, Jason Chen, Marietta Vazquez, Jaimie Meyer
A 64-year-old immunocompetent man developed a widespread pruritic and vesicular rash 2 weeks after receiving the zoster vaccine (Zostavax). He had fever, bandaemia with normal total white blood cell count and mild transaminitis. PCR testing of serum and skin was positive for varicella zoster virus (VZV), while serum VZV IgG was negative. The analysis of single nucleotide polymorphism by PCR and sequencing from the skin swab was consistent with the vaccine strain. The patient received 1 week of intravenous acyclovir and was discharged after all lesions had crusted...
August 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28827121/a-scid-mouse-human-lung-xenograft-model-of-varicella-zoster-virus-infection
#7
Wei Wang, Dequan Pan, Wenkun Fu, Linli Cai, Jianghui Ye, Jian Liu, Che Liu, Xiumin Huang, Yanzhen Lin, Ningshao Xia, Tong Cheng, Hua Zhu
Varicella pneumonia is one of the most serious, potentially life-threatening complications of primary varicella-zoster virus (VZV) infection in adults and immunocompromised individuals. However, studies on the lung pathogenesis of VZV infection as well as development and testing of antivirals have long been hindered by limited access to clinical samples and a lack of suitable animal models. In this study, we report for the first time the use of human lung xenografts in SCID mice for investigating VZV infection...
August 18, 2017: Antiviral Research
https://www.readbyqxmd.com/read/28808209/herpes-zoster-in-breast-cancer-a-case-report
#8
Mohammad Darvishi, Narges Vasei
There is little information on herpes zoster infection in breast cancer patients as a complication during adjuvant chemotherapy. We report a case of herpes zoster in a 65-year-old woman presented with low grade fever and vital signs together with skin symptoms such as severe edema, irritation and itching in the left breast where there was wound drainage. PCR test revealed varicella zoster virus. To the best of our knowledge, the histologic features coupled with PCR led to a diagnosis of herpes zoster.
July 13, 2017: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28804114/clinical-epidemiological-and-etiological-studies-of-adult-aseptic-meningitis-report-of-11-cases-with-varicella-zoster-virus-meningitis
#9
Shinichi Takeshima, Yuji Shiga, Takahiro Himeno, Keisuke Tachiyama, Teppei Kamimura, Ryuhei Kono, Makoto Takemaru, Jun Takeshita, Yutaka Shimoe, Masaru Kuriyama
We treated 11 cases (52.7 ± 14.9 years, all male) with varicella zoster virus (VZV) meningitis and 437 cases with adult aseptic meningitis from 2004 to 2016. The incidence rate of adult VZV meningitis in the cases with aseptic meningitis was 2.5%. Herpes zoster infections are reported to have occurred frequently in summer and autumn. VZV meningitis also occurred frequently in the similar seasons, in our patients. The diagnoses were confirmed in 9 cases with positive VZV-DNA in the cerebrospinal fluid and in 2 cases with high VZV-IgG indexes (> 2...
August 11, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/28780657/combination-therapy-of-rituximab-and-mycophenolate-mofetil-in-childhood-lupus-nephritis
#10
Julien Hogan, Astrid Godron, Véronique Baudouin, Theresa Kwon, Jérôme Harambat, Georges Deschênes, Olivier Niel
BACKGROUND: In clinical trials, the addition of rituximab (RTX) to the combination therapeutic regimen of mycophenolate mofetil (MMF) and corticosteroids failed to improve outcome in lupus nephritis (LN). However, recent data suggest that RTX may have steroid-sparing beneficial effects with an efficacy similar to that of conventional regimens. We report our experience with RTX in the treatment of children with LN. METHODS: Patients treated with RTX for first occurrence of LN class III to V were enrolled in the study...
August 5, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28740587/complications-of-varicella-zoster-infection-of-the-central-nervous-system
#11
Anusha S Thomas, Jose A Perez
No abstract text is available yet for this article.
April 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/28735059/too-young-to-be-vaccinated-hospitalizations-caused-by-varicella-among-children-in-the-first-year-of-life
#12
Ewelina Gowin, Jacek Wysocki, Michał Michalak, Danuta Januszkiewicz-Lewandowska
AIM: The aim of this study was to analyse the causes of hospitalization in the course of varicella in children during the first year of life. METHODS: An analysis was performed of the medical documentation of 359 children hospitalized for varicella on the infectious diseases ward at the Children's Hospital in Poznan (Poland) between January 2007 and August 2015. RESULTS: Of the 359 children in the study group, 96 were younger than 1 year old...
July 19, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28730326/infectious-diseases-causing-autonomic-dysfunction
#13
REVIEW
Francisco Javier Carod Artal
OBJECTIVES: To review infectious diseases that may cause autonomic dysfunction. METHODS: Review of published papers indexed in medline/embase. RESULTS: Autonomic dysfunction has been reported in retrovirus (human immunodeficiency virus (HIV), human T-lymphotropic virus), herpes viruses, flavivirus, enterovirus 71 and lyssavirus infections. Autonomic dysfunction is relatively common in HIV-infected patients and heart rate variability is reduced even in early stages of infection...
July 20, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28725563/atypical-hemolytic-uremic-syndrome-triggered-by-varicella-infection
#14
Pauline Condom, Jean-Michel Mansuy, Stéphane Decramer, Jacques Izopet, Catherine Mengelle
Varicella Zoster Virus (VZV) is a well-known virus that belongs to the Herpesviridae family which induces a self-limited disease except in specific cases in particular among stem cell transplant patients. This virus is not known however to trigger atypical Hemolytic Uremic Syndrome (aHUS). Here we report the case of a six-year-old boy who was hospitalized with fever and abdominal pains associated to pruritic and vesicular rash, thrombocytopenia and acute renal failure. He was diagnosed with aHUS precipitated by varicella virus...
2017: IDCases
https://www.readbyqxmd.com/read/28705842/facial-palsy-and-atrial-fibrillation-a-special-case-of-ramsay-hunt-syndrome
#15
Fares Ayoub, Dhruv Mahtta, Roland-Austin Federico, Michael Kaufmann
Ramsay Hunt syndrome (herpes zoster oticus) is a rare complication of latent Varicella Zoster virus infection. It can be complicated by permanent hearing loss, loss of taste and postherpetic neuralgia. Although Ramsay Hunt syndrome most prominently involves the facial nerve, a number of other cranial nerves can be involved such as the vestibulocochlear, glossopharyngeal and the vagus nerve. We report on a case of Ramsay Hunt syndrome with cranial polyneuritis complicated by atrial fibrillation. Vagal involvement as evidenced by physical examination and MRI findings was present in our patient...
July 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28705150/economic-burden-of-varicella-in-children-1-12%C3%A2-years-of-age-in-hungary-2011-2015
#16
Z Meszner, Z Molnar, E Rampakakis, H K Yang, B J Kuter, Lara J Wolfson
BACKGROUND: Although live-attenuated varicella-zoster virus (VZV) vaccines have been proven to be safe and effective in preventing varicella and real-word evidence shows routine childhood immunization programs are effective in dramatically reducing varicella associated morbidity and mortality, varicella vaccine is not included in the National Immunization Program (NIP) in Hungary. The purpose of this study was to evaluate the clinical and economic burden associated with varicella in Hungary...
July 14, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28666730/risk-factors-for-secondary-glaucoma-in-herpetic-anterior-uveitis
#17
Lisette Hoeksema, Nomdo M Jansonius, Leonoor I Los
PURPOSE: To determine the incidence of elevated intraocular pressure (IOP) and secondary glaucoma in herpetic anterior uveitis (AU), owing to either herpes simplex or varicella zoster virus, by using the Standardization of Uveitis Nomenclature (SUN) criteria, and to identify risk factors for the development of glaucoma. DESIGN: Retrospective observational cohort study. METHODS: Patients with herpetic AU presenting themselves between 2001 and 2013 at the ophthalmology department of the University Medical Center Groningen were included...
September 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28662876/herpes-zoster-involving-the-second-division-of%C3%A2-the-trigeminal-nerve-case-report-and-literature%C3%A2-review
#18
Rebecca Paquin, Lisiane F Susin, Garrett Welch, Jonathan B Barnes, Mark R Stevens, Franklin R Tay
Herpes zoster along the maxillary division of the trigeminal nerve is a rare condition that is caused by reactivation of the varicella zoster virus that resides within the trigeminal ganglion after the primary infection of chickenpox. The disease may be manifested as a toothache during its prodromal stage. The active stage of the disease is characterized by the appearance of a vesicular rash. Postherpetic neuralgia is a common complication of herpes zoster after resolution of the facial and intraoral symptoms...
June 26, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28657969/varicella-related-primary-healthcare-visits-hospitalizations-and-mortality-in-norway-2008-2014
#19
Grazina Mirinaviciute, Erle Kristensen, Britt Nakstad, Elmira Flem
BACKGROUND: Norway does not currently implement universal varicella vaccination in childhood. We aimed to characterize healthcare burden of varicella in Norway in the pre-vaccine era. METHODS: We linked individual patient data from different national registries to examine varicella vaccinations and varicella-coded primary care consultations, hospitalizations, outpatient hospital visits, deaths, and viral infections of central nervous system (CNS) in the whole population of Norway during 2008-2014...
June 27, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28646959/is-chickenpox-so-bad-what-do-we-know-about-immunity-to-varicella-zoster-virus-and-what-does-it-tell-us-about-the-future
#20
Anne A Gershon
Varicella and zoster continue to cause significant morbidity and even mortality in children and adults. Complications include bacterial superinfection, central nervous system manifestations such as meningitis, encephalitis, and cerebellar ataxia, and pain syndromes especially post herpetic neuralgia. Many developed countries but not all, are now administering live attenuated varicella vaccine routinely, with a decrease in the incidence of disease, providing personal and herd immunity. There is some controversy, however, in some countries concerning whether a decrease in the circulation of wild type virus will result in loss of immunity to VZV in persons who have already had varicella...
June 2017: Journal of Infection
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