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https://www.readbyqxmd.com/read/29649379/decrease-of-plasma-soluble-pro-renin-receptor-by-bariatric-surgery-in-patients-with-obstructive-sleep-apnea-and-morbid-obesity
#1
Tsuguo Nishijima, Koji Ohba, Shigeaki Baba, Testuya Kizawa, Keisuke Hosokawa, Fumiyo Endo, Yoshihiro Yamashiro, Akira Suwabe, Akira Sasaki, Kazuhiro Takahashi, Shigeru Sakurai
BACKGROUND: Plasma concentrations of soluble (pro)renin receptor [s(P)RR], which are elevated in patients with obstructive sleep apnea (OSA), have not been studied in morbid obesity. The aim of this study is to clarify effects of bariatric surgery on plasma s(P)RR concentrations and identify associated factors for their changes in OSA patients with morbid obesity. METHODS: Twenty-three patients with OSA complicated by morbid obesity (10 men and 13 women; body mass index, 40...
March 20, 2018: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29644903/patients-with-chronic-rhinosinusitis-and-obstructive-sleep-apnea-have-increased-paroxysmal-limb-movement
#2
Mahboobeh Mahdavinia, Jessica W Hui, Mohamed Zitun, Alejandra Lastra, James J Herdegen, Christopher D Codispoti, Rafsa J Khan, Phillip S LoSavio, Pete S Batra
BACKGROUND: Patients with chronic rhinosinusitis (CRS) frequently experience sleep disruption and are at a higher than normal risk for obstructive sleep apnea (OSA). The purpose of this study was to determine how CRS affects polysomnography findings and sleep-related breathing in OSA. METHODS: A cohort study was performed that included 107 adult patients with CRS and comorbid OSA (CRS+OSA group) and 137 patients with OSA and without CRS as the control group. An electronic medical records database was used to identify eligible subjects...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29642990/oral-interventions-for-obstructive-sleep-apnea
#3
Vasiliki Koretsi, Theodore Eliades, Spyridon N Papageorgiou
BACKGROUND: The effectiveness of intraoral appliances (IOA), maxillary expansion (ME), and maxillomandibular advancement (MMA) in the treatment of children and adults with obstructive sleep apnea (OSA) has not yet been adequately assessed. METHODS: An umbrella review was performed based on established guidelines for evidence-based medicine. Data synthesis was performed only from randomized controlled trials with Paule-Mandel random-effects meta-analyses / meta-regressions using mean differences (MDs) and 95% confidence intervals (CIs) and was followed by the qualitative evaluation of the meta-evidence...
March 23, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29628442/obstructive-sleep-apnea-and-effects-of-cpap-on-triglyceride-rich-lipoprotein-metabolism
#4
Luciano F Drager, Thauany M Tavoni, Vanessa M Silva, Raul D Santos, Rodrigo P Pedrosa, Luiz A Bortolotto, Carmen G C Vinagre, Vsevolod Y Polotsky, Geraldo Lorenzi-Filho, Raul C Maranhao
This study aimed to explore lipoprotein metabolism in Obstructive Sleep Apnea (OSA) and the effects of continuous positive airway pressure (CPAP). We studied 15 men with severe OSA (apnea-hypopnea index, AHI ≥30 events/hour) and 12 age, body mass index and waist circumference-matched volunteers without OSA (AHI <5 events/hour). Carotid intima-media thickness (CIMT) was determined by a blind examiner. After 12 hours fasting, a triglyceride-rich chylomicron-like emulsion, labeled with [14C]-cholesterol ester and [3H]-triolein was injected intravenously followed by blood samples collection at pre-established time...
April 8, 2018: Journal of Lipid Research
https://www.readbyqxmd.com/read/29625769/correlation-between-body-mass-index-and-obstructive-sleep-apnea-severity-indexes-a-retrospective-study
#5
Domenico Ciavarella, Michele Tepedino, Claudio Chimenti, Giuseppe Troiano, Manuela Mazzotta, Maria Pia Foschino Barbaro, Lorenzo Lo Muzio, Michele Cassano
PURPOSE: To evaluate if Body Mass Index (BMI) is correlated to Apnea-Hypopnea Index (AHI), mean arterial oxygen saturation (SaO2 ) and Nadir SaO2 , which are all indexes defining the severity of the respiratory stress associated with Obstructive Sleep Apnea (OSA). MATERIALS AND METHODS: Seventy-five adult patients (mean age 51.4) referred for polysomnography were retrospectively recruited. BMI was calculated for each patient, as well as AHI, SaO2 , and Nadir SaO2 recorded during polysomnography...
March 27, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29624601/sleep-apnea-detection-by-a-cardiac-resynchronization-device-integrated-thoracic-impedance-sensor-a-validation-study-against-the-gold-standard-polysomnography
#6
Fabian Barbieri, Wolfgang Dichtl, Anna Heidbreder, Elisabeth Brandauer, Ambra Stefani, Agne Adukauskaite, Thomas Senoner, Wilfried Schgör, Florian Hintringer, Birgit Högl
BACKGROUND: Sleep disordered breathing is a common but often undiagnosed comorbidity in heart failure patients. Cardiac implantable electronic devices used for cardiac resynchronization therapy (CRT) may detect sleep apnea by use of a transthoracic impedance sensor. Validation of the AP scan® algorithm (Boston Scientific®) was performed by using the diagnostic gold standard polysomnography (PSG). METHODS: Forty-one patients with impaired left ventricular ejection fraction, frequent right ventricular pacing due to atrioventricular block and heart failure symptoms despite optimal medical therapy underwent upgrading to biventricular pacing...
2018: PloS One
https://www.readbyqxmd.com/read/29623253/partial-reversal-of-color-vision-impairment-in-type-2-diabetes-associated-with-obstructive-sleep-apnea
#7
Rajiv Raman, Aditya Verma, Sangeetha Srinivasan, Deepak Bhojwani
Objective: Tritan anomaly is a known acquired color defect seen in diabetic patients, with or without the evidence of clinical signs of diabetic retinopathy (DR). We report a case of a 45-year-old diabetic patient with tritan pattern color defect associated with obstructive sleep apnea and its partial reversal with continuous positive airway pressure (CPAP) ventilation. Methods: A 45-year-old male with diabetes, wildlife photographer by profession, presented with specific complaints of seeing all objects in the surrounding with a greenish tinge in both the eyes...
2018: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/29622460/prevalence-and-clinical-characteristics-of-obstructive-and-central-dominant-sleep-apnea-in-candidates-of-catheter-ablation-for-atrial-fibrillation-in-japan
#8
Takashi Kohno, Takehiro Kimura, Koichi Fukunaga, Wakako Yamasawa, Taishi Fujisawa, Ryoma Fukuoka, Kazuaki Nakajima, Shin Kashimura, Akira Kunitomi, Yoshinori Katsumata, Takahiko Nishiyama, Nobuhiro Nishiyama, Yoshiyasu Aizawa, Keiichi Fukuda, Seiji Takatsuki
INTRODUCTION: We aimed to study the prevalence and types of sleep apnea (SA) as well as their clinical characteristics in atrial fibrillation (AF) ablation candidates in Japan. METHODS: Before catheter ablation, 197 consecutive AF patients (age: 60 ± 9 years, body mass index; 25.0 ± 3.0) were evaluated with portable polygraphy. We compared the clinical characteristics, according to the severity of SA as well as its types, as defined by the presence of obstruction and the mixed vs...
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29619152/comparison-of-berlin-questionnaire-stop-bang-and-epworth-sleepiness-scale-for-diagnosing-obstructive-sleep-apnea-in-persian-patients
#9
Babak Amra, Maedeh Javani, Forogh Soltaninejad, Thomas Penzel, Ingo Fietze, Christoph Schoebel, Ziba Farajzadegan
Background: Obstructive sleep apnea (OSA) is a common disorder characterized by snoring, daytime sleepiness, fatigue, and repeated termination of airflow (apnea). Standard polysomnography (PSG) is diagnostic gold standard for OSA. PSG is expensive and not available everywhere. To identify the best OSA questionnaire for screening in Persian population, we compared Berlin, STOP-BANG, and Epworth Sleepiness Scale (ESS). Methods: In a cross-sectional study conducted on 400 adult patients suspected of OSA in Bamdad Respiratory Research Center, patients completed three questionnaires...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29617152/comparison-of-pre-and-postoperative-sleep-studies-in-patients-undergoing-sphincter-pharyngoplasty
#10
Christina M Busuito, Nathan Vandjelovic, Diana M Flis, Arlene Rozzelle
OBJECTIVE: To determine if sphincter pharyngoplasty changes sleep study parameters on patients undergoing surgery for velopharyngeal insufficiency (VPI). DESIGN: Retrospective chart review on patients undergoing sphincter pharyngoplasty for VPI with pre- and postoperative polysomnography completed. SETTING: Institutional study at a tertiary pediatric hospital. PATIENTS: All patients who underwent sphincter pharyngoplasty over a 20-year period were reviewed; all patients with both pre- and postoperative sleep studies were collected for evaluation...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29614906/effect-of-rapid-eye-movement-related-obstructive-sleep-apnea-on-adherence-to-continuous-positive-airway-pressure
#11
Tetsuro Hoshino, Ryujiro Sasanabe, Tohru Tanigawa, Kenta Murotani, Mariko Arimoto, Hiromi Ueda, Toshiaki Shiomi
Objective Rapid eye movement (REM)-related obstructive sleep apnea (OSA) is characterized by respiratory events such as apnea and hypopnea predominately or exclusively during REM sleep. Several studies have revealed clinical predictors of adherence to the use of continuous positive airway pressure (CPAP). However, the effect of REM-related OSA on adherence to CPAP use remains unclear. Therefore, we investigated the effects of REM-related OSA on adherence to CPAP use 6 months after treatment initiation. Methods We enrolled 161 patients in this study and divided them into 3 groups: the good adherence, poor adherence, and dropout groups...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29609721/high-interrater-reliability-of-overnight-pulse-oximetry-interpretation-among-inexperienced-physicians-using-a-structured-template
#12
Mirna Ayache, Kingman P Strohl
STUDY OBJECTIVES: To assess the interrater reliability and accuracy of overnight pulse oximetry (OPO) interpretations by pulmonary fellows using a comprehensive structured template and after a brief educational session. METHODS: Using the template, four pulmonary and critical care (PCC) fellows interpreted OPO saturation waveforms and parameters extracted from 50 adult consecutive in-laboratory sleep studies. The template included three saturation parameters (mean saturation, oxygen desaturation index [ODI], and cumulative desaturation time) and description of the saturation waveform...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29609720/heart-rate-variability-responses-of-individuals-with-and-without-saline-induced-obstructive-sleep-apnea
#13
Daniel Vena, T Douglas Bradley, Philip J Millar, John S Floras, Jonathan Rubianto, Bojan Gavrilovic, Elisa Perger, Azadeh Yadollahi
STUDY OBJECTIVES: Postoperative development of obstructive sleep apnea (OSA) has been attributed to the fluid overloaded state of patients during the postoperative period. In this context, alterations in cardiac autonomic regulation caused by OSA may explain the increased postoperative risk for adverse cardiovascular events. This study tests the hypothesis that individuals with fluid overload-induced OSA will experience autonomic dysregulation, compared to those without fluid overload-induced OSA...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29609714/reliability-and-validity-of-the-functional-outcomes-of-sleep-questionnaire-spanish-short-version-fosq-10sv-in-peruvian-patients-with-obstructive-sleep-apnea
#14
Jorge Rey de Castro, Edmundo Rosales-Mayor, Terri E Weaver
STUDY OBJECTIVES: The aim of this study was to verify the reliability and validity of the Spanish short version of the Functional Outcomes of Sleep Questionnaire (FOSQ-10SV) in Peruvian patients with obstructive sleep apnea (OSA). METHODS: Participants underwent physical examinations, completed the FOSQ-10SV, and polysomnography tests were carried out. RESULTS: A total of 672 patients were analyzed, 75 females (11%), mean age 50.5 ± 13.8 years...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29609709/integrating-the-divided-nasal-cannula-into-routine-polysomnography-to-assess-nasal-cycle-feasibility-and-effect-on-outcomes
#15
Marcelo Scapuccin, Logan Schneider, Nur Rashid, Soroush Zaghi, Talita Rosa, Yung-An Tsuo, Stanley Liu, Paulo Lazarini, Robson Capasso, Chad Ruoff
STUDY OBJECTIVES: Patients suspected to have sleep-disordered breathing underwent an overnight polysomnography using a divided nasal cannula to gain additional information about the nasal cycle during sleep. METHODS: This was a prospective, observational cohort study replacing the undivided nasal cannula with a divided nasal cannula during routine polysomnography (n = 28). RESULTS: Integration of the divided nasal cannula pressure transducer system into routine polysomnography was easy and affordable...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29609708/effects-of-bedroom-environmental-conditions-on-the-severity-of-obstructive-sleep-apnea
#16
Sattamat Lappharat, Nutta Taneepanichskul, Sirimon Reutrakul, Naricha Chirakalwasan
STUDY OBJECTIVES: Epidemiological associations have demonstrated the effects of long-term air pollution to obstructive sleep apnea (OSA) through a physiological mechanism linking particulate matter exposure to OSA. This study aimed to determine the relationship between bedroom environmental conditions, OSA severity, and sleep quality. METHODS: Sixty-three participants were enrolled for an overnight polysomnography; OSA was diagnosed between May to August 2016. Personal characteristics and sleep quality were obtained by a face-to-face interview...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29609707/the-role-of-functional-respiratory-imaging-in-treatment-selection-of-children-with-obstructive-sleep-apnea-and-down-syndrome
#17
Monique A L J Slaats, Dieter Loterman, Cedric van Holsbeke, Wim Vos, Kim Van Hoorenbeeck, Jan de Backer, Wilfried de Backer, Marek Wojciechowski, An Boudewyns, Stijn Verhulst
STUDY OBJECTIVES: The complexity of the pathogenesis of obstructive sleep apnea (OSA) in children with Down syndrome (DS) is illustrated by a prevalence of residual OSA after adenotonsillectomy. The aim of this study was to investigate whether upper airway imaging combined with computation fluid dynamics could characterize treatment outcome after adenotonsillectomy in these children. METHODS: Children with DS and OSA were prospectively included. All children underwent an evaluation of the upper airway and an ultra-low dose computed tomography scan of the upper airway before adenotonsillectomy...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29609704/role-of-positive-airway-pressure-therapy-for-obstructive-sleep-apnea-in-patients-with-stroke-a-randomized-controlled-trial
#18
Anupama Gupta, Garima Shukla, Mohammed Afsar, Shivani Poornima, Ravindra M Pandey, Vinay Goyal, Achal Srivastava, Deepti Vibha, Madhuri Behari
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) is an independent risk factor for stroke. The objective of this study was to assess the effect of continuous positive airway pressure (CPAP) treatment on prevention of new vascular events among patients with stroke and OSA. METHODS: Consecutive conscious patients presenting with first imaging-confirmed arterial stroke were included, 6 weeks or more after ictus. All patients underwent clinical and polysomnography (PSG) testing...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29607972/gender-differences-in-the-clinical-features-of-sleep-apnea-syndrome
#19
Yuki Mieno, Masamichi Hayashi, Hiroki Sakakibara, Hiroshi Takahashi, Shiho Fujita, Sumito Isogai, Yasuhiro Goto, Sakurako Uozu, Mitsushi Okazawa, Kazuyoshi Imaizumi
Objectives Sleep apnea syndrome is more prevalent among men than women and is frequently accompanied by metabolic syndrome (MetS). However, gender differences in the effect of sleep-disordered breathing (SDB) leading to the risk of MetS remain unclear. The aim of our study was to investigate the clinical characteristics of SDB in women and the differential influence of SDB on MetS between genders. Methods In a single-center retrospective study, we compared the data of 1,809 consecutive SDB patients by gender to clarify the characteristics of sleep disorders in women...
March 30, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29605357/obstructive-sleep-apnea-syndrome-and-growth-failure
#20
E Esteller, J C Villatoro, A Agüero, R Lopez, E Matiñó, J Argemi, M Girabent-Farrés
Obstructive sleep apnea syndrome is a common problem among children and is recognized as a cause of significant medical morbidity. Since the 1980s, it has been suggested that obstructive sleep apnea syndrome is a risk factor for growth failure in children. In many cases, it has been shown that growth failure is reversible once the obstructive sleep apnea syndrome is resolved. The objectives of this study were to analyze and compare growth failure prevalence in a Mediterranean population of children with obstructive sleep apnea syndrome and healthy children matched in age and sex, and to assess the effectiveness of tonsillectomy and adenoidectomy in resolving growth retardation...
May 2018: International Journal of Pediatric Otorhinolaryngology
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