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https://www.readbyqxmd.com/read/29236274/outcomes-of-adenotonsillectomy-in-severe-pediatric-obstructive-sleep-apnea
#1
Karim El-Kersh, Rodrigo Cavallazzi, Egambaram Senthilvel
We conducted a retrospective chart review to examine the efficacy of adenotonsillectomy for the treatment of severe obstructive sleep apnea (OSA) in children. Our study population was made up of 85 patients-58 boys and 27 girls, aged 1 to 17 years (mean: 6.9 ± 4.4)-with severe OSA who had undergone adenotonsillectomy and pre- and postoperative attended polysomnography (PSG) over a 4-year period. Severe OSA was defined as an apnea-hypopnea index (AHI) of >10 events per hour of sleep. Patients who had an underlying genetic or craniofacial anomaly were excluded...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29231011/-research-progress-of-the-relationship-between-sunds-and-osahs
#2
REVIEW
Y D Wu, L Y Zhang, J D Cheng
Sudden unexplained nocturnal death syndrome (SUNDS) is always a difficulty in forensic medicine researches. Although the development of molecular genetics promotes the etiologic study of SUNDS, the pathogenesis of most such cases is still unclear. Sleep apnea syndrome (SAS) is one of the common forms of sleep disorders, and obstructive sleep apnea hypopnea syndrome (OSAHS) is the most common. In recent years, some domestic and international researches show that OSAHS is related to the development of cardiovascular disease, which may cause cardiac arrhythmia, even sudden death...
February 2017: Fa Yi Xue za Zhi
https://www.readbyqxmd.com/read/29229100/sleep-related-respiratory-events-during-non-invasive-ventilation-of-patients-with-chronic-hypoventilation
#3
Sigurd Aarrestad, Magnus Qvarfort, Anne Louise Kleiven, Elin Tollefsen, Ole Henning Skjønsberg, Jean-Paul Janssens
BACKGROUND: Non-invasive ventilation (NIV) is increasingly used in the treatment of patients with chronic hypercapnic respiratory failure (CRF). Residual sleep related respiratory events under NIV such as obstructive or central apnea/hypopnea (AH), or patient-ventilator asynchrony (PVA), may compromise treatment efficacy and/or comfort. AIMS OF STUDY: 1/to quantify the frequency and describe the types of both AH and PVA in a large group of stable patients with CRF during night-time NIV; 2/to analyze the influence of these events on overnight pulse oximetry and transcutaneous CO2 and 3/to assess interrater agreement in identifying and quantifying AH and PVA...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29228525/sleep-apnea-and-idiopathic-leg-edema-a-case-control-study
#4
Reza Shahmirzai, Mohammadreza Firouzifar
Idiopathic leg edema is subject to a lot of debates among physicians. Recently sleep apnea was stated to be the cause. We sought to investigate this matter in a sample of Iranian patients with idiopathic leg edema. In this case-control study, 110 patients were selected based on our inclusion/exclusion criteria and allocated to the case (with idiopathic edema, n=55) and control (without edema, n=55) groups. Sex, age, weight, height, and body mass index (BMI) of all subjects were recorded. We evaluated daytime somnolence of all patients using Epworth sleepiness scale and then calculated Apnea, hypopnea index (AHI) using ResMed ApneaLink and AHI≥15 were considered as sleep apnea...
October 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/29224042/association-between-continuous-positive-airway-pressure-and-serum-aminotransferases-in-patients-with-obstructive-sleep-apnea
#5
Li-Da Chen, Liang-Ji Zhang, Xue-Jun Lin, Jia-Chao Qi, Hao Li, Zhi Wu, Qiao-Zhen Xu, Ya-Ping Huang, Li Lin
INTRODUCTION: Obstructive sleep apnea (OSA) has been suggested to be a potential contributing factor for nonalcoholic fatty liver disease (NAFLD). Studies on the association between continuous positive airway pressure (CPAP) and NAFLD in OSA patients are limited and controversial. OBJECTIVES: The aim of this study was to assess the relationship between OSA and NAFLD and the effect of CPAP therapy on serum aminotransferase levels in OSA patients. METHODS: A total of 160 consecutive patients who underwent standard polysomnography were enrolled...
December 9, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29222619/improvement-in-obstructive-sleep-apnea-after-a-tailored-behavioural-sleep%C3%A2-medicine-intervention-targeting-healthy-eating-and-physical-activity-a-randomised-controlled-trial
#6
Helena Igelström, Pernilla Åsenlöf, Margareta Emtner, Eva Lindberg
PURPOSE: The aim of the present single-centre randomised controlled trial was to assess the effect of a behavioural sleep medicine (BSM) intervention on obstructive sleep apnea (OSA) severity in patients who have been referred for new treatment with continuous positive airway pressure (CPAP). METHODS: After baseline assessment including ventilatory and anthropometric parameters, and physical activity monitoring, 86 patients who were overweight (BMI ≥ 25) and had moderate-severe OSA with apnea-hypopnea index (AHI) ≥ 15 were randomised into a control group (CG; CPAP and advice about weight loss) or an experimental group (ExpG; CPAP and BSM intervention targeting physical activity and eating behaviour)...
December 8, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29221777/prevalence-of-sleep-apnea-at-the-acute-phase-of-ischemic-stroke-with%C3%A2-or-without-thrombolysis
#7
Jaana K Huhtakangas, Juha Huhtakangas, Risto Bloigu, Tarja Saaresranta
OBJECTIVE: The aim of the study was to compare the prevalence, type, and severity of sleep apnea during the acute phase of ischemic stroke among patients either receiving or not receiving thrombolysis. METHODS: We recruited 246 consecutive adult ischemic stroke patients. Patients underwent cardiorespiratory sleep study with portable three-channel device during the first 48 h after the symptom onset of ischemic stroke. RESULTS: We enrolled 110 (65...
December 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29221695/sleep-disordered-breathing-among-newborns-with-myelomeningocele
#8
Renée A Shellhaas, Payal V Kenia, Fauziya Hassan, John D E Barks, Niko Kaciroti, Ronald D Chervin
In a matched cohort study, we report that the apnea-hypopnea index is significantly higher in neonates with myelomeningocele (34 ± 22) compared with age-matched controls (19 ± 11; P = .021). Assessment of newborns with myelomeningocele for sleep-disordered breathing may facilitate early treatment; the impact on long-term neurodevelopment is unknown.
December 6, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29217205/increased-urinary-erythropoietin-excretion-in-severe-sleep-apnea-hipoapnea-syndrome-the-effect-of-cpap
#9
Miquel Félez, Nuria Grau, Antonia Ruiz, Encarna Guardiola, Carles Sanjuas, Cristina Estirado, Maribel Navarro-Muñoz, Antoni Pascual, Mauricio Orozco-Levi, Joaquim Gea
INTRODUCTION: Tissue hypoxia stimulates the production of erythropoietin (EPO), the main effect of which is, in turn, to stimulate erythropoiesis. Sleep apnea-hypopnea syndrome (SAHS) is an entity characterized by repeated episodes of hypoxemia during sleep. OBJECTIVE: To analyze whether hypoxemia stimulated increased urinary excretion of EPO, and if so, to evaluate if treatment with continuous positive airway pressure (CPAP) can inhibit this phenomenon. METHODS: We studied 25 subjects with suspected SAHS who underwent a polysomnography study (PSG)...
December 4, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/29214378/the-effectiveness-of-two-types-of-mads-for-osa-therapy
#10
Francis Emma Verburg, Klara Hilda Alphonsine Bollen, Henk-Jan Donker, Gerbrand Johannes Cornelis Kramer
OBJECTIVES: The purpose of this study was to determine differences in effectiveness between two types of mandibular advancement device (MAD). MATERIAL AND METHODS: In this retrospective, cohort study, the two devices used were MAD type "Somnodent-Flex" (MAD 1) and MAD type "Herbst" (MAD 2). One hundred thirty-seven patients participated in this study, 67 patients were treated with MAD 1, and 70 patients with MAD 2. The indication MAD with obstructive sleep apnea (OSA) is based on a polysomnography test, in accordance with the CBO guidelines...
December 6, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29212465/association-of-24%C3%A2-h-systolic-blood-pressure-variability-and-cardiovascular-disease-in-patients-with-obstructive-sleep-apnea
#11
Xiao Ke, Yan Sun, Rongfeng Yang, Jiawen Liang, Shaoyun Wu, Chengheng Hu, Xing Wang
BACKGROUND: To evaluate association of 24 h-systolic blood pressure (SBP) variability and obstructive sleep apnea (OSA) as defined by the apnea-hypopnea index ≥5/h; and association of 24 h-SBP variability and prevalent cardiovascular disease (CVD) in OSA patients. METHODS: Participants underwent polysomongraphy to evaluate the presence of OSA, and 24 h-ambulatory blood pressure monitoring was applied to evaluate 24 h-SBP variability as indexed by weighted 24 h-standard deviation (SD) of SBP...
December 6, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29211505/the-effect-of-dietary-nitrate-on-nocturnal-sleep-disordered-breathing-and-arterial-oxygen-desaturation-at-high-altitude
#12
Alexander Patrician, Harald Engan, David Lundsten, Ludger Grote, Helena Vigetun-Haughey, Erika Schagatay
Patrician, Alexander, Harald Engan, David Lundsten, Ludger Grote, Helena Vigetun-Haughey, and Erika Schagatay. The effect of dietary nitrate on nocturnal sleep-disordered breathing and arterial oxygen desaturation at high altitude. High Alt Med Biol 00:000-000, 2017.-Sleep-disordered breathing and fluctuations in arterial oxygen saturation (SaO2) are common during sleep among lowlanders ascending to high altitude. Dietary nitrate (NO3-) supplementation has been shown to lower the O2 consumption in various conditions...
December 6, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29208477/impact-of-opioid-therapy-on-sleep-and-respiratory-patterns-in-adults-with-advanced-cancer-receiving-palliative-care
#13
Phillip Good, Ross Pinkerton, Simon Bowler, Justin Craig, Janet Hardy
CONTEXT: In advanced cancer, abnormal sleep patterns may contribute to poor quality of life but the impact of opioid related sleep disorders has not been explored in detail in these patients. OBJECTIVE: To document sleep and respiratory patterns in patients with cancer, receiving a range of opioids, determine factors that contribute to severity of central or obstructive apnoea and to what extent these contribute to sleep disturbance. METHODS: Adults with advanced cancer admitted to a palliative care service underwent a sleep analysis by an unattended polysomnograph...
December 2, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29206630/does-untreated-obstructive-sleep-apnea-cause-secondary-erythrocytosis
#14
Christopher D Nguyen, Jon-Erik C Holty
BACKGROUND: The current literature suggests a relationship between obstructive sleep apnea (OSA) severity and hematocrit. However, the degree that OSA contributes to clinically significant erythrocytosis is uncertain. The aim of this study is to evaluate this association in a large study sample controlling for multiple confounders. METHODS: We evaluated consecutive subjects with suspected untreated OSA using multivariate analysis to test the associations between apnea-hypopnea index (AHI) and hematocrit...
September 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29205391/association-of-palatine-tonsil-size-and-obstructive-sleep-apnea-in-adults
#15
Sebastian M Jara, Edward M Weaver
OBJECTIVE: The relationship between palatine tonsil (PT) size and obstructive sleep apnea (OSA) has not been well established in adults. The purpose of this study was to test the association between PT grade, PT volume, and OSA severity in U.S. adult patients. STUDY DESIGN: Cross-sectional study of all patients (age ≥ 18 years) who underwent pharyngeal surgery for OSA that included palatine tonsillectomy with tonsil volume measurement from January 2011 to June 2016...
December 5, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29205091/polysomnographic-oxygen-saturation-findings-for-preteen-children-versus-adolescents
#16
Nathan D Wiebracht, Shan He, Colin Cotton, Jareen Meinzen-Derr, Gordon Shott, David F Smith, Keith B McConnell, Stacey L Ishman
Objective Home oximetry is commonly used to screen for obstructive sleep apnea (OSA) in children; however, normal oxygen desaturation levels by disease severity are not well known. It was our objective to determine if oxygen saturation levels differed by OSA severity category in children and if these differences were similar for preteen children and adolescents. Study Design Retrospective case series of children undergoing polysomnography from September 2011 to July 2015. Setting Tertiary pediatric hospital...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204589/hyoid-myotomy-and-suspension-without-simultaneous-palate-or-tongue-base-surgery%C3%A2-for-obstructive-sleep-apnea
#17
Adrian A Ong, Jonathan Buttram, Shaun A Nguyen, Dustin Platter, Michael R Abidin, M Boyd Gillespie
Objective: Determine the effects of hyoid myotomy and suspension (HMS) without concurrent palatal or tongue base sleep surgery for obstructive sleep apnea (OSA). Method: Patients with OSA treated with HMS were identified using CPT code (21685) at an academic and private sleep surgery clinic. Those who underwent concurrent palatal or tongue base sleep surgery were excluded. Outcomes included simultaneous procedures, apnea-hypopnea index (AHI), lowest oxyhemoglobin saturation (LSAT), and Epworth Sleepiness Scale (ESS)...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204587/transoral-robotic-surgery-vs-endoscopic-partial-midline-glossectomy-for-obstructive-sleep-apnea
#18
David Folk, Mark D'Agostino
Objective: To compare sleep-related outcomes in obstructive sleep apnea hypopnea syndrome (OSAHS) patients following base of tongue resection via robotic surgery and endoscopic midline glossectomy. Methods: This was a retrospective study. A total of 114 robotic and 37 endoscopic midline glossectomy surgeries were performed between July 2010 and April 2015 as part of single or multilevel surgery. Patients were excluded for indications other than sleep apnea or if complete sleep studies were not obtained...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204586/transoral-robotic-surgery-for-obstructive-sleep-apnea-syndrome-principles-and-technique
#19
Claudio Vicini, Filippo Montevecchi, Riccardo Gobbi, Andrea De Vito, Giuseppe Meccariello
Objective: The present study is a review of transoral robotic surgery (TORS) for the treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: The review presents the experience of the robotic center that developed the technique with regards to patient selection, surgical method, and post-operative care. In addition, the review provides results of a systematic review and meta-analysis of the complications and clinical outcomes of TORS when applied in the management of OSAHS...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204444/the-finite-element-simulation-of-the-upper-airway-of-patients-with-moderate-and-severe-obstructive-sleep-apnea-hypopnea-syndrome
#20
Huiping Luo, Austin Scholp, Jack J Jiang
Objectives: To investigate the snoring modes of patients with Obstructive Sleep Apnea Hypopnea Syndrome and to discover the main sources of snoring in soft tissue vibrations. Methods: A three-dimensional finite element model was developed with SolidEdge to simulate the human upper airway. The inherent modal simulation was conducted to obtain the frequencies and the corresponding shapes of the soft tissue vibrations. The respiration process was simulated with the fluid-solid interaction method through ANSYS...
2017: BioMed Research International
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