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https://www.readbyqxmd.com/read/29136026/operative-technique-at-caesarean-delivery-and-risk-of-complete-uterine-rupture-in-a-subsequent-trial-of-labour-at-term-a-registry-case-control-study
#1
Dorthe L A Thisted, Laust H Mortensen, Lone Hvidman, Lone Krebs
OBJECTIVE: To estimate the relation of single-layer closure at previous caesarean delivery, and other pre-labour and intra-partum risk factors for complete uterine rupture in trial of vaginal birth after a caesarean (TOLAC) at term. STUDY DESIGN: Population-based case-control study. We identified all women (n = 39 742) recorded in the Danish Medical Birth Registry (DMBR) during a 12-year period (1997-2008) with a singleton pregnancy at term and TOLAC. Among these, all women with a complete uterine rupture were identified (cases)...
2017: PloS One
https://www.readbyqxmd.com/read/29133313/site-specific-cancer-mortality-inequalities-by-employment-and-occupational-groups-a-cohort-study-among-belgian-adults-2001-2011
#2
Katrien Vanthomme, Laura Van den Borre, Hadewijch Vandenheede, Paulien Hagedoorn, Sylvie Gadeyne
OBJECTIVE: This study probes into site-specific cancer mortality inequalities by employment and occupational group among Belgians, adjusted for other indicators of socioeconomic (SE) position. DESIGN: This cohort study is based on record linkage between the Belgian censuses of 1991 and 2001 and register data on emigration and mortality for 01/10/2001 to 31/12/2011. SETTING: Belgium. PARTICIPANTS: The study population contains all Belgians within the economically active age (25-65 years) at the census of 1991...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29122446/review-of-the-comparative-effectiveness-of-radical-prostatectomy-radiation-therapy-or-expectant-management-of-localized-prostate-cancer-in-registry-data
#3
REVIEW
Emily C Serrell, Daniel Pitts, Matthew Hayn, Lisa Beaule, Moritz H Hansen, Jesse D Sammon
Evidence regarding the effectiveness of treatment for prostate cancer is primarily based on randomized controlled trials. Long-term outcomes are generally difficult to evaluate within experimental studies and may benefit from large pools of observational data. We conducted a systematic review of administrative and registry studies to evaluate the comparative effectiveness of treatment for clinically localized prostate cancer on overall and prostate-cancer specific mortality. MATERIALS AND METHODS: In accordance with the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P, 2015), we conducted a systematic search of Ovid Medline and Embase (1946-February 2017) and identified studies that evaluated the relationship between types of treatment for localized prostate cancer and mortality...
November 6, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29121647/update-of-the-dutch-manual-for-costing-studies-in-health-care
#4
Tim A Kanters, Clazien A M Bouwmans, Naomi van der Linden, Siok Swan Tan, Leona Hakkaart-van Roijen
OBJECTIVES: Dutch health economic guidelines include a costing manual, which describes preferred research methodology for costing studies and reference prices to ensure high quality studies and comparability between study outcomes. This paper describes the most important revisions of the costing manual compared to the previous version. METHODS: An online survey was sent out to potential users of the costing manual to identify topics for improvement. The costing manual was aligned with contemporary health economic guidelines...
2017: PloS One
https://www.readbyqxmd.com/read/29119022/bruch-s-membrane-opening-minimum-rim-width-measurement-with-sd-oct-a-method-to-correct-for-the-opening-size-of-bruch-s-membrane
#5
Robert Kromer, Martin Stephan Spitzer
A precise evaluation of the retinal nerve fiber layer thickness (RNFLT) is key for diagnosing and monitoring glaucoma. The Bruch's membrane opening minimum rim width (BMO-MRW) has been proposed as a reproducible assessment of the optic nerve. The BMO-MRW measures the minimum distance from the BMO to the internal limiting membrane. We propose an approach to correct the BMO-MRW using the BMO size for increased accuracy in interindividual comparisons in future studies. Eighty-one healthy patients received SPECTRALIS spectral domain optical coherence tomography measurements for the peripapillary RNFLT and BMO-MRW...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29114284/intraoperative-magnetic-resonance-imaging-for-cranial-and-spinal-cases-using-preexisting-c-shaped-three-side-open-0-2-tesla-magnetic-resonance-imaging
#6
Vinod Kumar Tewari, Ravindra Tripathi, Subodh Aggarwal, Mazhar Hussain, Hari Kishan Das Gupta
Background: The existing Intraoperative MRI (IMRI) of developed countries is too costly to be affordable in any developing country and out of the reach of common and poor people of developing country at remote areas. We have used the pre-existing (refurbished) 3 side open "C" shaped 0.2 Tesla MRI for IMRI in a very remote area. Materials and Methods: In this technique the 0.2 Tesla MRI and the operating theatre were merged. MRI table was used as an operation table...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29110807/psychobiological-correlates-of-vaginismus-an-exploratory-analysis
#7
Elisa Maseroli, Irene Scavello, Sarah Cipriani, Manuela Palma, Massimiliano Fambrini, Giovanni Corona, Edoardo Mannucci, Mario Maggi, Linda Vignozzi
BACKGROUND: Evidence concerning the determinants of vaginismus (V), in particular medical conditions, is inconclusive. AIM: To investigate, in a cohort of subjects consulting for female sexual dysfunction, whether there is a difference in medical and psychosocial parameters between women with V and women with other sexual complaints. METHODS: A series of 255 women attending our clinic for female sexual dysfunction was consecutively recruited...
November 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29103607/experience-with-an-on-site-coronary-computed-tomography-derived-fractional-flow-reserve-algorithm-for-the-assessment-of-intermediate-coronary-stenoses
#8
Patrick M Donnelly, Márton Kolossváry, Júlia Karády, Peter A Ball, Stephanie Kelly, Donna Fitzsimons, Mark S Spence, Csilla Celeng, Tamás Horváth, Bálint Szilveszter, Hendrik W van Es, Martin J Swaans, Béla Merkely, Pál Maurovich-Horvat
Fractional flow reserve (FFR) derived from coronary computed tomography angiography (CTA) is a new technique for the diagnosis of ischemic coronary artery stenoses. The aim of this prospective study was to evaluate the diagnostic performance of a novel on-site computed tomography-based fractional flow reserve algorithm (CT-FFR) compared with invasive FFR as the gold standard, and to determine whether its diagnostic performance is affected by interobserver variations in lumen segmentation. We enrolled 44 consecutive patients (64...
October 10, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29103302/continuous-glucose-monitoring-measures-can-be-used-for-glycemic-control-in-the-icu-an-in-silico-study
#9
Tony Zhou, Jennifer L Dickson, Geoffrey M Shaw, J Geoffrey Chase
BACKGROUND: Continuous glucose monitoring (CGM) technology has become more prevalent in the intensive care unit (ICU), offering potential benefits of increased safety and reduced workload in glycemic control (GC). The drift and higher point accuracy errors of CGM devices over traditional intermittent blood glucose (BG) measures have so far limited their application in the ICU. This study delineates the trade-offs of performance, safety and workload that CGM sensors provide in GC protocols...
November 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29093366/a-japanese-stress-check-program-screening-tool-predicts-employee-long-term-sickness-absence-a-prospective-study
#10
Akizumi Tsutsumi, Akihito Shimazu, Hisashi Eguchi, Akiomi Inoue, Norito Kawakami
ObjectivesOn December 1, 2015, the Japanese government launched the Stress Check Program, a new occupational health policy to screen employees for high psychosocial stress in the workplace. As only weak evidence exists for the effectiveness of the program, we sought to estimate the risk of stress-associated long-term sickness absence as defined in the program manual.MethodsParticipants were 7356 male and 7362 female employees in a financial service company who completed the Brief Job Stress Questionnaire (BJSQ)...
November 1, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/29093065/low-dose-aspirin-and-risk-of-intracranial-bleeds-an-observational-study-in-uk-general-practice
#11
Lucía Cea Soriano, David Gaist, Montse Soriano-Gabarró, Susan Bromley, Luis A García Rodríguez
OBJECTIVE: To quantify the risk of intracranial bleeds (ICBs) associated with new use of prophylactic low-dose aspirin using a population-based primary care database in the United Kingdom. METHODS: A cohort of new users of low-dose aspirin (75-300 mg; n = 199,079) aged 40-84 years and a 1:1 matched cohort of nonusers of low-dose aspirin at baseline were followed (maximum 14 years, median 5.4 years) to identify incident cases of ICB, with validation by manual review of patient records or linkage to hospitalization data...
November 1, 2017: Neurology
https://www.readbyqxmd.com/read/29092919/aortic-valve-replacement-associated-with-survival-in-severe-regurgitation-and-low-ejection-fraction
#12
Amy G Fiedler, Vijeta Bhambhani, Elizabeth Laikhter, Michael H Picard, Meagan M Wasfy, George Tolis, Serguei Melnitchouk, Thoralf M Sundt, Jason H Wasfy
OBJECTIVES: Although guidelines support aortic valve replacement (AVR) in patients with severe aortic regurgitation (AR) and left ventricular ejection fraction (LVEF) <50%, severe left ventricular dysfunction (LVEF <35%) is thought to confer high surgical risk. We sought to determine if a survival benefit exists with AVR compared with medical management in this high-risk, relatively rare population. METHODS: A large institutional echocardiography database was queried to identify patients with severe AR and LVEF <35%...
November 1, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29090475/a-multi-centre-randomized-clinical-trial-of-oral-hygiene-interventions-following-stroke-a-6-months-trial
#13
Normaliza Ab Malik, Saari Mohamad Yatim, Fathilah Abdul Razak, Otto Lok Tao Lam, Lijian Jin, Leonard S W Li, Colman McGrath
BACKGROUND: Maintaining good oral hygiene is important following stroke. OBJECTIVES: This study aimed to evaluate the effectiveness of two oral health promotion (OHP) programmes to reduce dental plaque levels following stroke. METHODS: A multi-center randomized clinical control trial was conducted among patients hospitalised following stroke in Malaysia. Patients were randomly allocated to two OHP groups: i) control group who received the conventional method for plaque control - daily manual tooth brushing with a standardized commercial toothpaste, ii) test group - who received an intense method for plaque control - daily powered tooth brushing with 1% Chlorhexidine gel...
November 1, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29089957/development-and-evaluation-of-a-barley-50k-iselect-snp-array
#14
Micha M Bayer, Paulo Rapazote-Flores, Martin Ganal, Pete E Hedley, Malcolm Macaulay, Jörg Plieske, Luke Ramsay, Joanne Russell, Paul D Shaw, William Thomas, Robbie Waugh
High-throughput genotyping arrays continue to be an attractive, cost-effective alternative to sequencing based approaches. We have developed a new 50k Illumina Infinium iSelect genotyping array for barley, a cereal crop species of major international importance. The majority of SNPs on the array have been extracted from variants called in exome capture data of a wide range of European barley germplasm. We used the recently published barley pseudomolecule assembly to map the exome capture data, which allowed us to generate markers with accurate physical positions and detailed gene annotation...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29089341/mechanical-cardiopulmonary-resuscitation-and-hospital-survival-among-adult-patients-with-nontraumatic-out-of-hospital-cardiac-arrest-attending-the-emergency-department-a-prospective-multicenter-observational-study-in-japan-sos-kanto-survey-of-survivors-after
#15
Kei Hayashida, Takashi Tagami, Tatsuma Fukuda, Masaru Suzuki, Naohiro Yonemoto, Yutaka Kondo, Tomoko Ogasawara, Atsushi Sakurai, Yoshio Tahara, Ken Nagao, Arino Yaguchi, Naoto Morimura
BACKGROUND: Mechanical cardiopulmonary resuscitation (mCPR) for patients with out-of-hospital cardiac arrest attending the emergency department has become more widespread in Japan. The objective of this study is to determine the association between the mCPR in the emergency department and clinical outcomes. METHODS AND RESULTS: In a prospective, multicenter, observational study, adult patients with out-of-hospital cardiac arrest with sustained circulatory arrest on hospital arrival were identified...
October 31, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29080494/aqme-a-forensic-mitochondrial-dna-analysis-tool-for-next-generation-sequencing-data
#16
Kimberly Sturk-Andreaggi, Michelle A Peck, Cecilie Boysen, Patrick Dekker, Timothy P McMahon, Charla K Marshall
The feasibility of generating mitochondrial DNA (mtDNA) data has expanded considerably with the advent of next-generation sequencing (NGS), specifically in the generation of entire mtDNA genome (mitogenome) sequences. However, the analysis of these data has emerged as the greatest challenge to implementation in forensics. To address this need, a custom toolkit for use in the CLC Genomics Workbench (QIAGEN, Hilden, Germany) was developed through a collaborative effort between the Armed Forces Medical Examiner System - Armed Forces DNA Identification Laboratory (AFMES-AFDIL) and QIAGEN Bioinformatics...
September 19, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29076750/investigation-of-dental-cone-beam-ct-pixel-data-and-a-modified-method-for-conversion-to-hounsfield-units-hu
#17
Dennise Magill, Natalie Beckmann, Marc A Felice, Thomas Yoo, Minou Luo, Mel Mupparapu
OBJECTIVES: To investigate the relationship in dental Cone-Beam CT (CBCT) between the manufacturer-reported image pixel data and a modified conversion to CT number densities in Hounsfield Units (HU). METHODS: A standardized CT phantom was imaged using typical clinical parameters on CBCT from 3 manufacturers (Carestream 9300®, J Morita 3D Accutomo®, and Planmeca Promax 3D®). Reconstructed axial slices were evaluated using regions of interest to ascertain the mean pixel value in 5 materials in the phantom...
October 27, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29076469/-use-of-the-intellivent-asv-mode-for-maintaining-the-target-etco2-range-in-patients-with-severe-tbi
#18
E P Anan'ev, A A Polupan, I V Matskovskiy, A V Oshorov, A S Goryachev, I A Savin, A A Sychev, T F Tabasaranskiy, V V Podlepich, K Yu Krylov, A A Pashin, O E Satishur, L Piquilloud, D Novotni, A A Potapov, Ya V Savchenko
PURPOSE: the study purpose was to evaluate the efficacy of the IntelliVent-ASV mode in maintaining the target range of PaCO2 in patients with severe TBI. MATERIAL AND METHODS: The study included 12 severe TBI patients with the wakefulness level scored 4-9 (GCS). This was a crossover design study. Two ventilation modes were consecutively used: IntelliVent-ASV and P-CMV, for 12 h each. When using the P-CMV mode, the ventilation parameters were set to maintain PaCO2 in a range of 35-38 mm Hg...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/29074055/tacrolimus-improves-symptoms-of-children-with-myasthenia-gravis-refractory-to-prednisone
#19
Chanchan Liu, Mengcui Gui, Yayun Cao, Jing Lin, Yue Li, Suqiong Ji, Bitao Bu
BACKGROUND: Myasthenia gravis tends to affect children in China. Oral pyridostigmine and prednisone could effectively improve the symptoms, but multiple side effects become a major concern after long-term oral prednisone. To avoid the long-term complications of prednisone therapy and to obtain more satisfactory improvement, we tested the efficacy and safety of tacrolimus in children with myasthenia gravis. METHODS: Children with myasthenia gravis who had not achieved satisfactory improvement or who experienced severe side effects after prednisone therapy were recruited between January 2015 and December 2016 at Tongji Hospital...
September 5, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29071958/-effect-of-electroacupuncture-on-cerebro-cortex-caspase-3-expression-and-blood-lipid-levels-in-hyperlipemia-rats-with-cerebral-ischemia
#20
Zhuo-Yu Wang, Jia-Jia Ma, Han-Yu Guan, Yao Tian, Xiu-Jun Ren, Hui-Fang Ma
OBJECTIVE: To observe the effect of electroacupuncture (EA) stimulation of "Fenglong" (ST 40), "Sanyinjiao" (SP 6) plus manual acupuncture (MA) stimulation of "Shuigou" (GV 26) and "Baihui" (GV 20) on Caspase-3 protein expression in the cerebral cortex of rats with hyperlipemia and cerebral ischemia(HL-CI),so as to reveal its mechanisms underlying improvement of HL-CI. METHODS: Forty-five rats were randomly divided into normal control,sham operation,model,EA group I(EA+MA was given for 14 days, i...
April 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
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