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https://www.readbyqxmd.com/read/28647194/prediction-of-6-minute-walk-performance-in-patients-with-peripheral-artery-disease
#1
Xi Chen, Julie A Stoner, Polly S Montgomery, Ana I Casanegra, Federico Silva-Palacios, Sixia Chen, Amanda E Janitz, Andrew W Gardner
BACKGROUND: Peripheral artery disease (PAD) is a highly prevalent disease that impairs walking ability. Walking tests, such as the 6-minute walk test (6MWT) and 4-meter walk test, are commonly used to assess exercise endurance and ambulatory function over a short distance, respectively. The 6MWT performance is predictive of PAD severity and disease outcomes, but it is not feasible in many clinical settings because it requires a long walkway to serve as the test route and lengthens clinic visits...
June 21, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28645019/using-network-screening-methods-to-determine-locations-with-specific-safety-issues-a-design-consistency-case-study
#2
Andrew J Butsick, Jonathan S Wood, Paul P Jovanis
The Highway Safety Manual provides multiple methods that can be used to identify sites with promise (SWiPs) for safety improvement. However, most of these methods cannot be used to identify sites with specific problems. Furthermore, given that infrastructure funding is often specified for use related to specific problems/programs, a method for identifying SWiPs related to those programs would be very useful. This research establishes a method for Identifying SWiPs with specific issues. This is accomplished using two safety performance functions (SPFs)...
June 20, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28641217/the-aggressor-at-the-mirror-psychiatric-correlates-of-deliberate-self-harm-in-male-prison-inmates
#3
N Verdolini, A Murru, L Attademo, R Garinella, I Pacchiarotti, C Del Mar Bonnin, L Samalin, L Pauselli, M Piselli, A Tamantini, R Quartesan, A F Carvalho, E Vieta, A Tortorella
BACKGROUND: Deliberate self-harm (DSH) causes important concern in prison inmates as it worsens morbidity and increases the risk for suicide. The aim of the present study is to investigate the prevalence and correlates of DSH in a large sample of male prisoners. METHODS: A cross-sectional study evaluated male prisoners aged 18+ years. Current and lifetime psychiatric diagnoses were assessed with the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders - DSM-IV Axis I and Axis II Disorders and with the Addiction Severity Index-Expanded Version...
April 14, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28640840/applying-artificial-intelligence-to-disease-staging-deep-learning-for-improved-staging-of-diabetic-retinopathy
#4
Hidenori Takahashi, Hironobu Tampo, Yusuke Arai, Yuji Inoue, Hidetoshi Kawashima
PURPOSE: Disease staging involves the assessment of disease severity or progression and is used for treatment selection. In diabetic retinopathy, disease staging using a wide area is more desirable than that using a limited area. We investigated if deep learning artificial intelligence (AI) could be used to grade diabetic retinopathy and determine treatment and prognosis. METHODS: The retrospective study analyzed 9,939 posterior pole photographs of 2,740 patients with diabetes...
2017: PloS One
https://www.readbyqxmd.com/read/28639611/masked-hypertension-and-effort-reward-imbalance-at-work-among-2369-white-collar-workers
#5
P Boucher, M Gilbert-Ouimet, X Trudel, C S Duchaine, A Milot, C Brisson
Hypertension is an important risk factor of cardiovascular diseases, the leading cause of death worldwide. Adverse effects of psychosocial factors at work might increase the risk of masked hypertension, but evidences are still scarce. The objective of this study is then to determine whether adverse psychosocial work factors from the effort-reward imbalance (ERI) model are associated with the prevalence of masked hypertension in a population of white-collar workers. White-collar workers were recruited from three public organizations...
June 22, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28633615/experts-opinion-on-manual-wheelchair-adjustments-for-adults-with-diabetes
#6
Sophie-Anne Scherrer, Joelle Chu Yu Chee, Nhi Vu, Patrice Lu, Michelle Ishack, Philippe S Archambault
Diabetes is a global health concern that can lead to mobility limitations necessitating a wheelchair. However, there are currently no guidelines for wheelchair adjustments tailored to the diabetic population. PURPOSE: To describe relevant manual wheelchair adjustments for adults with diabetes, and to explore how these adjustments apply to populations living in less-resourced countries. METHODS: Semi-structured interviews were conducted with 13 wheelchair experts from five different countries working with adult with diabetes...
March 2, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28629845/role-of-primary-motor-cortex-in-the-control-of-manual-dexterity-assessed-via-sequential-bilateral-lesion-in-the-adult-macaque-monkey-a-case-study
#7
Julie Savidan, Mélanie Kaeser, Abderraouf Belhaj-Saïf, Eric Schmidlin, Eric M Rouiller
From a case study, we describe the impact of unilateral lesion of the hand area in the primary motor cortex (M1) on manual dexterity and the role of the intact contralesional M1 in long-term functional recovery. An adult macaque monkey performed two manual dexterity tasks: (i) "modified Brinkman board" task, assessed simple precision grip versus complex precision grip, the latter involved a hand postural adjustment; (ii) "modified Klüver board" task, assessed movements ranging from power grip to precision grip, pre-shaping and grasping...
June 17, 2017: Neuroscience
https://www.readbyqxmd.com/read/28629355/biologically-constrained-optimization-based-cell-membrane-segmentation-in-c-elegans-embryos
#8
Yusuke Azuma, Shuichi Onami
BACKGROUND: Recent advances in bioimaging and automated analysis methods have enabled the large-scale systematic analysis of cellular dynamics during the embryonic development of Caenorhabditis elegans. Most of these analyses have focused on cell lineage tracing rather than cell shape dynamics. Cell shape analysis requires cell membrane segmentation, which is challenging because of insufficient resolution and image quality. This problem is currently solved by complicated segmentation methods requiring laborious and time consuming parameter adjustments...
June 19, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28621083/metacognition-in-speech-and-language-therapy-for-children-with-social-pragmatic-communication-disorders-implications-for-a-theory-of-therapy
#9
Jacqueline Gaile, Catherine Adams
BACKGROUND: Metacognition is a significant component of complex interventions for children who have developmental language disorders. Research into how metacognition operates in the content or process of developmental language therapy delivery is limited. Identification and description of proposed active therapy components, such as metacognition, may contribute to our understanding of how to deliver complex communication interventions in an optimal manner. AIMS: To analyse aspects of metacognition during therapy derived from a manualized speech and language intervention (the Social Communication Intervention Programme-SCIP) as delivered to children who have social (pragmatic) communication disorder (SPCD) and to examine the dynamic process of delivering therapy...
June 16, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28615767/do-life-events-and-social-support-vary-across-depressive-disorders
#10
Savitha Soman, Shripathy M Bhat, K S Latha, Samir Kumar Praharaj
BACKGROUND: Social support and life events moderate the expression of depression though studies have shown contradictory results. The objective was to study the stressful life events and perceived social support in patients with adjustment disorder, first-episode depression, and recurrent depressive disorder (RDD). SUBJECTS AND METHODS: One hundred and forty-six patients aged 18-60 years with adjustment disorder, first-episode depression, or RDD according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision were evaluated using the presumptive stressful life events scale and Multidimensional Scale of Perceived Social Support...
May 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28612050/a-rapid-segmentation-insensitive-digital-biopsy-method-for-radiomic-feature-extraction-method-and-pilot-study-using-ct-images-of-non-small-cell-lung-cancer
#11
Sebastian Echegaray, Viswam Nair, Michael Kadoch, Ann Leung, Daniel Rubin, Olivier Gevaert, Sandy Napel
Quantitative imaging approaches compute features within images' regions of interest. Segmentation is rarely completely automatic, requiring time-consuming editing by experts. We propose a new paradigm, called "digital biopsy," that allows for the collection of intensity- and texture-based features from these regions at least 1 order of magnitude faster than the current manual or semiautomated methods. A radiologist reviewed automated segmentations of lung nodules from 100 preoperative volume computed tomography scans of patients with non-small cell lung cancer, and manually adjusted the nodule boundaries in each section, to be used as a reference standard, requiring up to 45 minutes per nodule...
December 2016: Tomography: a Journal for Imaging Research
https://www.readbyqxmd.com/read/28611291/evaluation-of-the-7th-and-8th-editions-of-the-ajcc-uicc-tnm-staging-systems-for-lung-cancer-in-a-large-north-american-cohort
#12
Lin Yang, Shidan Wang, Yunyun Zhou, Sunny Lai, Guanghua Xiao, Adi Gazdar, Yang Xie
PURPOSE: The new 8th American Joint Committee on Cancer (AJCC)/International Union for Cancer Control (UICC) lung cancer staging system was developed and internally validated using the International Association for the Study of Lung Cancer (IASLC) database, but external validation is needed. The goal of this study is to validate the discriminatory ability and prognostic performance of this new staging system in a larger, independent non-small cell lung cancer (NSCLC) cohort with greater emphasis on North American patients...
May 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/28609199/smoking-in-irritable-bowel-syndrome-a-systematic-review
#13
Laura Sirri, Silvana Grandi, Eliana Tossani
OBJECTIVE: The aim of this review was to examine (1) the prevalence of smoking in subjects with irritable bowel syndrome (IBS), (2) whether smoking prevalence significantly differs between subjects with and without IBS, and (3) whether smoking significantly predicts the presence or the development of IBS. METHODS: Articles were retrieved by systematically searching the Scopus, Web of Science, and PubMed electronic databases from inception to July 2016, using the keywords "smoking" and "tobacco" combined with "irritable bowel syndrome...
June 13, 2017: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/28601311/the-prevalence-of-psychiatric-diagnoses-and-associated-mortality-in-hospitalized-us-trauma-patients
#14
Laura L Townsend, Micaela M Esquivel, Tarsicio Uribe-Leitz, Thomas G Weiser, Paul M Maggio, David A Spain, Lakshika Tennakoon, Kristan Staudenmayer
BACKGROUND: We hypothesized that psychiatric diagnoses would be common in hospitalized trauma patients in the United States and when present, would be associated with worse outcomes. MATERIALS AND METHODS: The Nationwide Inpatient Sample (NIS, 2012) was used to determine national estimates for the number of patients admitted with an injury. Psychiatric diagnoses were identified using diagnosis codes according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition...
June 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28598591/effect-of-split-file-digital-workflow-on-crown-margin-adaptation
#15
Ryan R Sheridan, Ronald Verrett, Stephan Haney, John Schoolfield
PURPOSE: Computer-aided design/computer-aided manufacturing (CAD/CAM) is becoming increasingly integrated into dental practice workflow at a pace that exceeds scientific validation. The aim of this study is to evaluate a complete digital split-file protocol relative to segmental digital and analog techniques for restoring a single maxillary anterior edentulous space with custom abutment and crown. MATERIALS AND METHODS: Four treatment workflows were assessed: complete digital (CD), segmental digital (SD), milled wax (AM), and heat pressed and hand waxed (AH) and heat pressed...
June 9, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28598180/evaluation-of-the-self-adjusting-file-system-saf-for-the-instrumentation-of-primary-molar-root-canals-a-micro-computed-tomographic-study
#16
E Kaya, M Elbay, D Yiğit
AIM: The Self-Adjusting File (SAF) system has been recommended for use in permanent teeth since it offers more conservative and effective root-canal preparation when compared to traditional rotary systems. However, no study had evaluated the usage of SAF in primary teeth. The aim of this study was to evaluate and compare the use of SAF, K file (manual instrumentation) and Profile (traditional rotary instrumentation) systems for primary-tooth root-canal preparation in terms of instrumentation time and amounts of dentin removed using micro-computed tomography (μCT) technology...
June 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28596251/hypothalamic-atrophy-is-related-to-body-mass-index-and-age-at-onset-in-amyotrophic-lateral-sclerosis
#17
Martin Gorges, Pauline Vercruysse, Hans-Peter Müller, Hans-Jürgen Huppertz, Angela Rosenbohm, Gabriele Nagel, Patrick Weydt, Åsa Petersén, Albert C Ludolph, Jan Kassubek, Luc Dupuis
OBJECTIVE: Our objective was to study the hypothalamic volume in a cohort of patients with amyotrophic lateral sclerosis (ALS) including symptomatic and presymptomatic ALS mutation carriers. METHODS: High-resolution three-dimensional T1-weighted MRI datasets from 251 patients with sporadic ALS, 19 symptomatic and 32 presymptomatic ALS mutation carriers and 112 healthy controls (HC) were retrospectivally registered for manual delineation of the hypothalamus. The volume of the hypothalamus, in total or subdivided, was normalised to the intracranial volume and adjusted to age...
June 8, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28594880/application-of-the-3d-slicer-chest-imaging-platform-segmentation-algorithm-for-large-lung-nodule-delineation
#18
Stephen S F Yip, Chintan Parmar, Daniel Blezek, Raul San Jose Estepar, Steve Pieper, John Kim, Hugo J W L Aerts
PURPOSE: Accurate segmentation of lung nodules is crucial in the development of imaging biomarkers for predicting malignancy of the nodules. Manual segmentation is time consuming and affected by inter-observer variability. We evaluated the robustness and accuracy of a publically available semiautomatic segmentation algorithm that is implemented in the 3D Slicer Chest Imaging Platform (CIP) and compared it with the performance of manual segmentation. METHODS: CT images of 354 manually segmented nodules were downloaded from the LIDC database...
2017: PloS One
https://www.readbyqxmd.com/read/28593116/bridging-the-gap-between-clinical-practice-and-public-health-using-ehr-data-to-assess-trends-in-the-seasonality-of-blood-pressure-control
#19
Aurora O Amoah, Sonia Y Angell, Hannah Byrnes-Enoch, Sam Amirfar, Phoenix Maa, Jason J Wang
Electronic health records (EHRs) provide timely access to millions of patient data records while limiting errors associated with manual data extraction. To demonstrate these advantages of EHRs to public health practice, we examine the ability of a EHR calculated blood-pressure (BP) measure to replicate seasonal variation as reported by prior studies that used manual data extraction. Our sample included 609 primary-care practices in New York City. BP control among hypertensives was defined as systolic blood pressure of 140 or less and diastolic blood pressure of 90 or less (BP < 140/90 mm Hg)...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28592811/evaluating-the-impact-of-vitreomacular-adhesion-on-anti-vegf-therapy-for-retinal-vein-occlusion-using-machine-learning
#20
Sebastian M Waldstein, Alessio Montuoro, Dominika Podkowinski, Ana-Maria Philip, Bianca S Gerendas, Hrvoje Bogunovic, Ursula Schmidt-Erfurth
Vitreomacular adhesion (VMA) represents a prognostic biomarker in the management of exudative macular disease using anti-vascular endothelial growth factor (VEGF) agents. However, manual evaluation of VMA in 3D optical coherence tomography (OCT) is laborious and data on its impact on therapy of retinal vein occlusion (RVO) are limited. The aim of this study was to (1) develop a fully automated segmentation algorithm for the posterior vitreous boundary and (2) to study the effect of VMA on anti-VEGF therapy for RVO...
June 7, 2017: Scientific Reports
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