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https://www.readbyqxmd.com/read/28447959/using-measurable-dosimetric-quantities-to-characterize-the-inter-structural-tradeoff-in-inverse-planning
#1
Hongcheng Liu, Peng Dong, Lei Xing
Traditional inverse planning relies on the use of weighting factors to balance the conflicting requirements of different structures. The manual trial-and-error determination of the weighting factors has long been recognized as a time-consuming part of treatment planning. The purpose of this work is to develop an inverse planning framework that parameterizes the dosimetric tradeoff among the structures with physically meaningful quantities to simplify the search for clinically sensible plans. In this formalism, instead of using the weighting factors, permissible variation range of the prescription dose or dose volume histogram (DVH) of the involved structures are used to characterize the "importance" of the structures...
April 27, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28444068/acute-bag-valve-breathing-maneuvers-plus-manual-chest-compression-is-safe-during-stable-septic-shock-a-randomized-clinical-trial
#2
Clarissa Netto Blattner, Rafael Saldanha Dos Santos, Fernando Suparregui Dias, Alexandre Simões Dias, Régis Gemerasca Mestriner, Silvia Regina Rios Vieira
Objective: To evaluate the effects of bag-valve breathing maneuvers combined with standard manual chest compression techniques on safety, hemodynamics and oxygenation in stable septic shock patients. Design: A parallel, assessor-blinded, randomized trial of two groups. A computer-generated list of random numbers was prepared by an independent researcher to allocate treatments. Setting: The Intensive Care Unit at Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul...
January 2017: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/28443488/socioeconomic-status-social-capital-and-self-reported-unmet-health-care-needs-a-population-based-study
#3
Christine Lindstrӧm, Maria Rosvall, Martin Lindstrӧm
AIMS: The aim of this study was to investigate the associations between socioeconomic status (SES) and self-reported unmet health care needs, taking economic stress, generalized trust in other people and trust in the health care system into account. METHODS: The 2012 public health survey in Scania was conducted using a postal questionnaire and included 28,029 participants aged 18-80 years. The study was cross-sectional. Associations between SES and unmet health care needs were investigated, adjusting for economic stress and trust in logistic regressions...
May 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28440922/pseudomonas-aeruginosa-and-post-tracheotomy-bacterial-respiratory-tract-infection-readmissions
#4
Christopher J Russell, Tamara D Simon, Mary R Mamey, Christopher J L Newth, Michael N Neely
OBJECTIVE: Identify risk factors for readmission due to a bacterial tracheostomy-associated respiratory tract infection (bTARTI) within 12 months of discharge after tracheotomy. DESIGN/METHODS: We performed a retrospective cohort study of 240 children who underwent tracheotomy and were discharged with tracheotsomy in place between January 1, 2005 and June 30, 2013. Children with prolonged total or post-tracheotomy length of stay (LOS), less than 12 months of follow-up, or who died during the index hospitalization were excluded...
April 25, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28439966/automated-fractional-limb-volume-measurements-improve-the-precision-of-birth-weight-predictions-in-late-third-trimester-fetuses
#5
Lauren M Mack, Sung Yoon Kim, Sungmin Lee, Haleh Sangi-Haghpeykar, Wesley Lee
OBJECTIVES: Fetal soft tissue can be assessed by using fractional limb volume as a proxy for in utero nutritional status. We investigated automated fractional limb volume for rapid estimate fetal weight assessment. METHODS: Pregnant women were prospectively scanned for 2- and 3-dimensional fetal biometric measurements within 4 days of delivery. Performance of birth weight prediction models was compared: (1) Hadlock (Am J Obstet Gynecol 1985; 151:333-337; biparietal diameter, abdominal circumference, and femur diaphysis length); and (2) Lee (Ultrasound Obstet Gynecol 2009; 34:556-565; biparietal diameter, abdominal circumference, and automated fractional limb volume)...
April 25, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28436022/ventilation-via-the-2-4%C3%A2-mm-internal-diameter-tritube-%C3%A2-with-cuff%C3%A2-new-possibilities-in-airway-management
#6
REVIEW
M S Kristensen, M W P de Wolf, L S Rasmussen
BACKGROUND: A small tube may facilitate tracheal intubation and improve surgical access. We describe our initial experience with the Tritube(®) that is a novel cuffed endotracheal tube with a 2.4 mm internal diameter. METHODS: The Tritube(®) was used in seven adult Ear-Nose-and Throat surgical patients with airway narrowing or whose surgical access was facilitated by this small-bore endotracheal tube. Ventilation through Tritube(®) is performed with the manually operated Ventrain(®) -ventilator that allows active suctioning during expiration, therefore facilitating normoventilation through small diameter airways...
April 23, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28430885/lesion-mapping-of-stroke-related-erectile-dysfunction
#7
Klemens Winder, Frank Seifert, Martin Köhrmann, Carl Crodel, Stephan Kloska, Arnd Dörfler, Katharina M Hösl, Stefan Schwab, Max J Hilz
Acute ischaemic stroke in brain areas contributing to male sexual function may impair erectile function depending on the lesion site. This study intended to determine associations between stroke-related erectile dysfunction and cerebral ischaemic lesion sites using voxel-based lesion mapping. In 52 males (mean age 60.5 ± 10.5 years) with first-ever ischaemic strokes, we assessed erectile function after and retrospectively 3 months prior to the stroke using scores of the 5-item International Index of Erectile Function-5 questionnaire...
April 18, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28424072/prevalence-of-intimate-partner-violence-and-its-association-with-symptoms-of-depression-a-cross-sectional-study-based-on-a-female-population-sample-in-sweden
#8
Solveig Lövestad, Jesper Löve, Marjan Vaez, Gunilla Krantz
BACKGROUND: Intimate Partner Violence (IPV) is the most common type of violence targeting women. IPV includes acts of physical aggression, sexual coercion, psychological abuse and controlling behaviors and these forms of violence often coexist in the same relationship. Living with IPV is associated with serious mental health outcomes such as depression and depressive symptoms. Few population based studies from Sweden have investigated the relationship between different forms of IPV and women's depressive symptoms and even fewer used controlling behavior as an independent variable in such studies...
April 20, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28422900/the-association-between-posttraumatic-stress-disorder-and-perceptions-of-deployment-related-injury-in-veterans-with-and-without-mild-traumatic-brain-injury
#9
Nazanin H Bahraini, Lindsey L Monteith, Holly R Gerber, Jeri E Forster, Trisha A Hostetter, Lisa A Brenner
OBJECTIVES: To examine whether the association between posttraumatic stress disorder (PTSD) and injury perceptions (ie, consequences, emotional representations, and coherence) differs for Veterans with mild traumatic brain injury (mTBI) compared with Veterans with non-TBI (ie, orthopedic). PARTICIPANTS: Eighty Veterans injured during post-9/11 deployments. DESIGN: Observational, 2×2 factorial design. MAIN MEASURES: Injury histories ascertained using the Ohio State University TBI-Identification Method and Deployment Injury Questionnaire; Injury Perception Questionnaire-Revised (injury perceptions); Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (PTSD diagnosis); and PTSD Symptom Checklist-Civilian Version (PTSD symptoms)...
April 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28422463/gingival-health-and-plaque-regrowth-response-following-a-four-week-interdental-hygiene-intervention
#10
Anthony Mwatha, Misty Olson, Sonia Souza, Marilyn Ward, Wendy Jenkins, Pejmon Amini, John Gallob, Theresa Fafard
OBJECTIVES: To compare the efficacy of three adjunct interproximal cleaning methods versus a manual toothbrush alone on gingivitis, and demonstrate that the Philips Sonicare AirflossPro™ interproximal (IP) cleaning device provides a similar reduction in gingivitis and plaque compared to string floss. METHODS: A randomized, single-blind, parallel-design study was conducted on generally healthy adults exhibiting mild to moderate gingivitis. Eligible subjects were non-smokers, aged 18-65 years, with ≥ 0...
March 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28422460/an-evaluation-of-plaque-and-gingivitis-reduction-following-home-use-of-sonicare-flexcare-platinum-with-premium-plaque-control-brush-head-and-a-manual-toothbrush
#11
Wendy Jenkins, Sonia Souza, Marilyn Ward, Jodi Defenbaugh, Kimberly R Milleman, Jeffery L Milleman
OBJECTIVES: To assess the effect of the Philips Sonicare FlexCare Platinum with Premium plaque control brush head on gingival inflammation, bleeding, and supragingival plaque reduction following a six-week period of home use compared to a manual toothbrush. METHODS: This was a randomized, single-blind, parallel-design clinical trial. Subjects included in the study were routine manual toothbrush users who were generally healthy non-smokers, aged 18-65 years, with mild to moderate gingivitis...
March 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28421682/predicting-abstinence-from-methamphetamine-use-after-residential-rehabilitation-findings-from-the-methamphetamine-treatment-evaluation-study
#12
Rebecca McKetin, Astrid Kothe, Amanda L Baker, Nicole K Lee, Joanne Ross, Dan I Lubman
INTRODUCTION AND AIMS: We previously found that residential rehabilitation increased continuous abstinence from methamphetamine use 1 year after treatment. We examine what client and treatment characteristics predict this outcome. DESIGN AND METHODS: Participants (n = 176) were dependent on methamphetamine and entering residential rehabilitation for methamphetamine use. Simultaneous logistic regression was used to identify independent predictors of continuous abstinence from methamphetamine use at 1 year follow-up...
April 18, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28419177/interpreting-patterns-of-low-scores-on-the-nih-toolbox-cognition-battery
#13
James A Holdnack, David S Tulsky, Brian L Brooks, Jerry Slotkin, Richard Gershon, Allen W Heinemann, Grant L Iverson
Introduction: The National Institutes of Health Toolbox for Assessment of Neurological and Behavioral Function Cognition Battery is comprised of seven cognitive tests, including two tests measuring crystallized cognitive ability (i.e., vocabulary and reading) and five tests measuring fluid cognitive functioning (i.e., working memory, memory, speed of processing, and executive functioning). This study presents comprehensive base rate tables for the frequency of low scores in adults and older adults from the normative sample...
April 17, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28416838/-clinical-research-on-robot-assisted-percutaneous-pelvic-and-acetabular-screws-surgery
#14
C P Zhao, J Q Wang, Y G Su, W Han, L Zhou, M Y Wang
OBJECTIVE: To evaluate the security and efficiency of a surgical robotic assisted percutaneous screw fixation for the treatment of pelvic and acetabular fractures. METHODS: In the study, 12 patients with pelvic and acetabular fractures who were treated in Beijing Jishuitan Hospital from January to April in 2016 were involved in this research. The research subjects were randomly divided into two groups: the experimental group and the control group. Robotic-assisted percutaneous sacroiliac screw internal fixations were performed under the guidance of fluoroscopy navigation in the experimental group; in the control group, doctors operated manually guided by fluoroscopy...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28416573/changes-in-directly-alcohol-attributable-mortality-during-the-great-recession-by-employment-status-in-spain-a-population-cohort-of-22-million-people
#15
Ignacio Alonso, Fernando Vallejo, Enrique Regidor, M José Belza, Luis Sordo, Laura Otero-García, Gregorio Barrio
BACKGROUND: Macroeconomic fluctuations can impact differentially on alcohol-related problems across sociodemographic groups. We assess trend changes in directly alcohol-attributable (DAA) mortality in the population aged 25-64 during the post-2008 recession in Spain according to employment status and other sociodemographic factors. METHODS: Nationwide cohort study covering 21.9 million people living in Spain in 2001. People were classified by employment status and other factors...
April 17, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28416265/comparison-of-outcomes-for-pediatric-paraphimosis-reduction-using-topical-anesthetic-versus-intravenous-procedural-sedation
#16
Brett Burstein, Raphael Paquin
BACKGROUND: Paraphimosis is an acute urologic emergency requiring urgent manual reduction, frequently necessitating procedural sedation (PS) in the pediatric population. The present study sought to compare outcomes among pediatric patients undergoing paraphimosis reduction using a novel topical anesthetic (TA) technique versus PS. METHODS: We performed a retrospective analysis of all patients <18years old, presenting to a tertiary pediatric ED requiring analgesia for paraphimosis reduction between October 2013 and September 2016...
April 11, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28413823/long-term-predictive-and-feedback-encoding-of-motor-signals-in-the-simple-spike-discharge-of-purkinje-cells
#17
Laurentiu S Popa, Martha L Streng, Timothy J Ebner
Most hypotheses of cerebellar function emphasize a role in real-time control of movements. However, the cerebellum's use of current information to adjust future movements and its involvement in sequencing, working memory, and attention argues for predicting and maintaining information over extended time windows. The present study examines the time course of Purkinje cell discharge modulation in the monkey (Macaca mulatta) during manual, pseudo-random tracking. Analysis of the simple spike firing from 183 Purkinje cells during tracking reveals modulation up to 2 s before and after kinematics and position error...
March 2017: ENeuro
https://www.readbyqxmd.com/read/28401450/reproducibility-and-prognostic-potential-of-ki-67-proliferation-index-when-comparing-digital-image-analysis-with-standard-semi-quantitative-evaluation-in-breast-cancer
#18
Balázs Ács, Lilla Madaras, Kristóf Attila Kovács, Tamás Micsik, Anna-Mária Tőkés, Balázs Győrffy, Janina Kulka, Attila Marcell Szász
In this study, the reproducibility of Ki-67 proliferation index (KIPI) was investigated by comparing the semi-quantitative (SQ) results of three assessors with those of digital image-analysis (DIA) methods. The prognostic significance of the two approaches was also correlated with clinical outcome. Tissue microarrays of duplicate 2 mm cores were constructed from representative areas of formalin-fixed and paraffin-embedded tumor blocks of 347 breast cancer patients. SQ evaluation of Ki-67 (MIB1 clone) immunostained slides was performed independently by three pathologists...
April 11, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28401340/seizure-threshold-increases-can-be-predicted-by-eeg-quality-in-right-unilateral-ultrabrief-ect
#19
Verònica Gálvez, Dusan Hadzi-Pavlovic, Susan Waite, Colleen K Loo
Increases in seizure threshold (ST) over a course of brief pulse ECT can be predicted by decreases in EEG quality, informing ECT dose adjustment to maintain adequate supra-threshold dosing. ST increases also occur over a course of right unilateral ultrabrief (RUL UB) ECT, but no data exist on the relationship between ST increases and EEG indices. This study (n = 35) investigated if increases in ST over RUL UB ECT treatments could be predicted by a decline in seizure quality. ST titration was performed at ECT session one and seven, with treatment dosing maintained stable (at 6-8 times ST) in intervening sessions...
April 11, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28393757/prehospital-randomised-assessment-of-a-mechanical-compression-device-in-out-of-hospital-cardiac-arrest-paramedic-a-pragmatic-cluster-randomised-trial-and-economic-evaluation
#20
Simon Gates, Ranjit Lall, Tom Quinn, Charles D Deakin, Matthew W Cooke, Jessica Horton, Sarah E Lamb, Anne-Marie Slowther, Malcolm Woollard, Andy Carson, Mike Smyth, Kate Wilson, Garry Parcell, Andrew Rosser, Richard Whitfield, Amanda Williams, Rebecca Jones, Helen Pocock, Nicola Brock, John Jm Black, John Wright, Kyee Han, Gary Shaw, Laura Blair, Joachim Marti, Claire Hulme, Christopher McCabe, Silviya Nikolova, Zenia Ferreira, Gavin D Perkins
BACKGROUND: Mechanical chest compression devices may help to maintain high-quality cardiopulmonary resuscitation (CPR), but little evidence exists for their effectiveness. We evaluated whether or not the introduction of Lund University Cardiopulmonary Assistance System-2 (LUCAS-2; Jolife AB, Lund, Sweden) mechanical CPR into front-line emergency response vehicles would improve survival from out-of-hospital cardiac arrest (OHCA). OBJECTIVE: Evaluation of the LUCAS-2 device as a routine ambulance service treatment for OHCA...
March 2017: Health Technology Assessment: HTA
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