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Cullen M Dutmer, Allison M Schiltz, Kristy L Freeman, Matthew J Christie, Juana A Cerna, Seung-Hyun Cho, Ryan T Chartier, Jonathan W Thornburg, Katharine L Hamlington, James L Crooks, Tasha E Fingerlin, David A Schwartz, Andrew H Liu
RATIONALE: Home dampness and mold are associated with asthma severity and exacerbations, but little is known about the nature of these exposures in at-risk children. OBJECTIVES: To test the hypothesis that observed dampness, water damage, and mold in the home are associated with higher exposure to particulate matter less than 10 μm in diameter in a cohort of at-risk children with asthma. METHODS: We performed a pilot study in 8- to 16-year-old children with exacerbation-prone asthma (n = 29; Denver Asthma Panel Study)...
April 2018: Annals of the American Thoracic Society
Akihiko Ando, Shoichiro Nagasaka, Shun Ishibashi
We report a case of a woman with diabetes mellitus caused by a genetic defect in ABCC8 -coding sulfonylurea receptor 1 (SUR1), a subunit of the ATP-sensitive potassium (KATP ) channel protein. She was diagnosed with diabetes at 7 days after birth. After intravenous insulin drip for 1 month, her hyperglycaemia remitted. At the age of 13 years, her diabetes relapsed, and after that she had been treated by intensive insulin therapy for 25 years with relatively poor glycaemic control. She was switched to oral sulfonylurea therapy and attained euglycaemia...
2018: Endocrinology, Diabetes & Metabolism Case Reports
M Schmid, M Maushammer, S Preuß, J Bennewitz
In this study, genome-wide association study (GWAS) results of porcine F2 crosses were used to map QTL in outcross Piétrain populations. For this purpose, two F2 crosses (Piétrain × Meishan, n = 304; Piétrain × Wild Boar, n = 291) were genotyped with the PorcineSNP60v2 BeadChip and phenotyped for the dressing yield, carcass length, daily gain and drip loss traits. GWASs were conducted in the pooled F2 cross applying single marker mixed linear models. For the investigated traits, between two and five (in total 15) QTL core regions, spanning 250 segregating SNPs around a significant trait-associated peak SNP, were identified...
April 19, 2018: Animal Genetics
J H Park, S I Lee, I H Kim
This study examined the effects of dietary Spirulina (Arthrospira) platensis supplementation on growth performance, antioxidant enzyme activity, nutrient digestibility, cecal microflora, excreta noxious gas emission, organ weight and breast meat quality in broiler chickens. In total, 800 Ross 308 male broiler chickens (1-d-old) were randomly divided into 5 dietary treatments with 10 replicate cages (16 birds/replicate) per treatment for 5 wk. The dietary treatments were a control basal diet without Spirulina or with 0...
April 17, 2018: Poultry Science
S Knaga, M Siwek, S Tavaniello, G Maiorano, A Witkowski, G Jezewska-Witkowska, M Bednarczyk, G Zieba
The objective of the current study was to identify QTL associated with body weight, growth rate, egg quality traits, concentration of selected blood plasma, and yolk lipids as well as concentration of selected macro- and microelements, color, pH, basic chemical composition, and drip loss of breast muscle of Japanese quail (Coturnix japonica). Twenty-two meat-type males (line F33) were crossed with twenty-two laying-type females (line S22) to produce a generation of F1 hybrids. The F2 generation was created by mating 44 randomly chosen F1 hybrids, which were full siblings...
April 17, 2018: Poultry Science
Joko Sujiwo, Dongwook Kim, Aera Jang
The aim of this study was to evaluate the relation among the quality and freshness traits of chicken breast meat during storage for 12 d at 4°C. In addition, correlations between freshness traits and torrymeter values were examined. The L* and a* value of the color was constant; however, the b* value increased on day 5 of storage (P < 0.05). The shear force value significantly decreased, whereas the 2-thiobarbituric acid reactive substances value significantly increased during storage. Regarding the sensory properties, the off-odor and the drip loss increased along with the decrease in color and overall acceptability evaluated by the panelist...
April 14, 2018: Poultry Science
H A Córdova-Noboa, E O Oviedo-Rondón, A H Sarsour, J Barnes, P Ferzola, M Rademacher-Heilshorn, U Braun
One experiment was conducted to evaluate the effects of guanidinoacetic acid (GAA) supplementation in broilers fed corn or sorghum-based diets on live performance, carcass and cut up yields, meat quality, and pectoral myopathies. The treatments consisted of corn or sorghum-based diets with or without the addition of GAA (600 g/ton). A total of 800 one-d-old male Ross 708 broiler chicks were randomly placed in 40 floor pens with 10 replicates (20 birds per pen) per each of the four treatments. At hatch, 14, 35, and 50 d, BW and feed intake were recorded...
April 13, 2018: Poultry Science
Guoran Ruan, Haojin Ren, Chi Zhang, Xiaogang Zhu, Chao Xu, Liyue Wang
QiShenYiQi dripping pills (QSYQ), a traditional Chinese medicine, are commonly used to treat coronary heart disease, and QSYQ was recently approved as a complementary treatment for ischemic heart failure in China. However, only few studies reported on whether QSYQ exerts a protective effect on heart failure induced by pressure overload. In this study, we explored the role of QSYQ in a mouse model of heart failure induced by transverse aortic constriction (TAC). Twenty-eight C57BL/6J mice were divided into four groups: Sham + NS group, Sham + QSYQ group, TAC + NS group, and TAC + QSYQ group...
2018: Frontiers in Physiology
Yubin Wang, Wu Li, Wenqian Cai, Yue Ma, Yong Xu, Xiaoyan Zhao, Chao Zhang
Drip loss of fresh-cut watermelon has become a concern for both producers and consumers. The effect of visible light exposure on the drip loss of fresh-cut watermelon was evaluated. Visible light treatments of 3000 and 10 Lux were applied to fresh-cut watermelon at 4 °C during the shelf life for 5 days, with light exposure of 150 Lux as the control. The drip loss of the fresh-cut watermelon at 3000 Lux was 74.8% of that at 150 Lux on the fifth day, and the moisture evaporation at 3000 Lux was 1.89 times that at 150 Lux...
May 2018: Journal of Food Science and Technology
Rajpreet Kaur Goraya, Usha Bajwa
Inclusion of processed amla have been found to enhance the functional properties and nutritional value of ice cream by augmenting the fiber content, total phenols, tannins, ascorbic acid and antioxidant activity. The present investigation assessed the changes in these constituents, color values (L, a* and b*), melting rate, sensory scores and microbiological quality of ice cream containing amla shreds, pulp, preserve, candy and powder during 60 days' storage at - 18 to - 20 °C. The total solids increased slightly whereas the antioxidant activity, total phenols, ascorbic acid and tannins decreased on storage...
May 2018: Journal of Food Science and Technology
Sugiharto Sugiharto, Isroli Isroli, Turrini Yudiarti, Endang Widiastuti
Aim: The aim of the present study was to investigate the effect of supplementation of multistrain probiotic preparation in combination with vitamins and minerals to the broiler chicken diets on their growth performance, hematological parameters, and carcass traits. Materials and Methods: Two hundred and eighty-eight Lohmann 1-day-old broiler chicks were randomly allocated to four groups, i.e., control (without additional supplementation) and three experimental treatments where basal diet was enriched by 0...
February 2018: Veterinary World
Xiujun Qin, Jingjing Yin, Wei Zhang, Jianguo Li, Jianhua Wen, Shizhong Chen
This article aims to conduct toxicity test research on honokiol microemulsion(HM) to provide reference frame for the safe dose design as well as the toxic and adverse reaction monitoring in clinic. High performance liquid chromatography (HPLC) method was adopted to determine the concentration, stability and uniformity of HM and the results indicated that the test sample was conformed to the toxicity test requirements. In the acute toxicity test, six intravenous drip dosages, namely, 100.0, 66.7, 44.4, 19.8, 8...
April 12, 2018: Regulatory Toxicology and Pharmacology: RTP
Shufang Wang, Xiyun Jiao, Weihua Guo, Jian Lu, Yungang Bai, Liping Wang
A suitable irrigation method adopted to arid desert conditions, including a special soil structure and specialized plants, has been continuously studied and improved. A field study was conducted in the Awei irrigation area of Aletai in Xinjiang in 2015 and 2016 to investigate the applicability of shallow subsurface drip irrigation (SSDI) in an arid desert area. A completely randomized block design with three replications and three treatments for drip tape subsurface depths at 5, 10, 20 cm was established. The results indicated that the vertical distribution of the soil moisture of subsurface drip irrigation (SDI, buried depth at 20 cm) was mainly concentrated at 0-60 cm, while SSDI (buried depth at 5 and 10 cm) was concentrated at 0-30 cm...
2018: PloS One
Tamanna Bhuyan, Mitradip Bhattacharjee, Amit Kumar Singh, Siddhartha Sankar Ghosh, Dipankar Bandyopadhyay
We demonstrate the feasibility of a self-propelling mushroom motor, namely a 'logibot', as a functional unit for the construction of a host of optimized binary logic gates. Emulating the chemokinesis of unicellular prokaryotes or eukaryotes, the logibots made stimuli responsive conditional movements at varied speeds towards a pair of acid-alkali triggers. A series of integrative logic operations and cascaded logic circuits, namely, AND, NAND, NOT, OR, NOR, and NIMPLY, have been constructed employing the decisive chemotactic migrations of the logibot in the presence of the pH gradient established by the sole or coupled effects of acid (HCl-catalase) and alkali (NaOH) drips inside a peroxide bath...
April 12, 2018: Soft Matter
Shenfei Long, Yetong Xu, Chunlin Wang, Changlian Li, Dewen Liu, Xiang-Shu Piao
Objective: This study was to evaluate effects of mixed plant oils [identified as mixed oil 1 (MO1) and mixed oil 2 (MO2)] on performance, serum composition, viscera percentages, meat quality, and fatty acid deposition of broilers. Methods: A total of 126 one-day-old Arbor Acres male broiler chicks (weighing 44.91 ± 0.92 g) were randomly allocated to 1 of 3 treatments with 7 replicate pens per treatment (6 broilers per pen). Dietary treatments included a corn-soybean basal diet supplemented with 3% soybean oil (CTR), basal diet with 3% MO1 (a mixture of 15% corn oil, 10% coconut oil, 15% linseed oil, 20% palm oil, 15% peanut oil and 25% soybean oil; MO1), or basal diet with 3% MO2 (a combination of 50% MO1 and 50% extruded corn; MO2)...
April 12, 2018: Asian-Australasian Journal of Animal Sciences
Thiago Vinicius Cortez, Isabella Rodrigues Ziotti, Renata Siqueira Scatolin, Silmara Aparecida Milori Corona, Aline Evangelista Souza-Gabriel
Purpose: Composite resin restorations are normally replaced after the internal bleaching of endodontically treated-teeth because the bleaching agent does not alter the color of the restorative material. This study evaluated the effect of 10% sodium ascorbate (SA) applied at different protocols on bleached dentin. Materials and Methods: One-hundred slabs of intracoronary bovine dentin were divided into 5 groups: 2 controls-GI without bleaching (positive), GII bleached with 35% hydrogen peroxide (HP) (negative); and 3 experimentals - GIII...
January 2018: Journal of Conservative Dentistry: JCD
Malavika Kulkarni, L S Chuchendra, P J Bhavya
Background: The onset time of neuromuscular blockade is a crucial time associated with the risk of hypoxia and pulmonary aspiration. Various strategies have been undertaken to shorten this onset time. Therefore, we investigated the effects of bolus of 20 ml saline followed by limb elevation after administration of rocuronium in a dose of 0.6 mg/kg to study the onset time. Methodology: Thirty patients were randomly allocated to the bolus saline group or control group...
January 2018: Anesthesia, Essays and Researches
Zhengmeng Ye, Xi Lu, Yi Deng, Xinquan Wang, Shuo Zheng, Hongmei Ren, Miao Zhang, Tingting Chen, Pedro A Jose, Jian Yang, Chunyu Zeng
BACKGROUND/AIMS: Adverse environment in utero can modulate adult phenotypes including blood pressure. Fine particulate matter (PM2.5) exposure in utero causes hypertension in the offspring, but the exact mechanisms are not clear. Renal dopamine D1 receptor (D1R), regulated by G protein-coupled receptor kinase type 4 (GRK4), plays an important role in the regulation of renal sodium transport and blood pressure. In this present study, we determined if renal D1R dysfunction is involved in PM2...
March 21, 2018: Cellular Physiology and Biochemistry
Ahmed S Elrys, Abdel-Rahman M A Merwad, Ahmed I E Abdo, Mohamed K Abdel-Fatah, El-Sayed M Desoky
Two field trials were carried out in two successive agricultural seasons to study the possibility of using silicon (Si) and Moringa seed extract (MSE) for reducing heavy metal contamination resulting from phosphate fertilizers addition to potato tubers. A randomized complete block design experiment was performed using three replicates. Various sources of phosphate fertilizers as ordinary super phosphate and rock phosphate were added at rate of 100 kg P ha-1 prior sowing. Silicon was added as potassium silicate (20% SiO2 ) at rate of 6 L ha-1 , and MSE was also added at rate of 150 L ha-1 in three equal doses with the 2nd, 4th, and 6th irrigations during the last 10 min of drip irrigation...
April 3, 2018: Environmental Science and Pollution Research International
M Smrecnik, Z Kavcic Trsinar, T Kocjan
Patients with Addison's disease are at greater risk of having reduced bone mineral density and hip fractures and are thus more likely to receive a bisphosphonate than their peers. Potent intravenous bisphosphonates could provoke an acute phase reaction. An 80-year-old female with Addison's disease received her first infusion of zoledronic acid for osteoporosis at our outpatient clinic around noon. Despite doubling her usual afternoon hydrocortisone dose, she became feverish, nauseous, extremely weak, and hypotensive over the night...
March 28, 2018: Osteoporosis International
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