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Gaspard Gerschenfeld, Ioan-Paul Muresan, Raphael Blanc, Michael Obadia, Marie Abrivard, Michel Piotin, Sonia Alamowitch
Importance: Intravenous thrombolysis (IVT) followed by mechanical thrombectomy (MT) is recommended to treat acute ischemic stroke (AIS) with a large vessel occlusion (LVO). Most hospitals do not have on-site MT facilities, and most patients need to be transferred secondarily after IVT (drip and ship), which may have an effect on the neurologic outcome. Objective: To compare the functional independence at 3 months between patients treated under the drip-and-ship paradigm and those treated on site (mothership)...
March 20, 2017: JAMA Neurology
Nazim Bozan, Yunus Feyyat Sakin, Pinar Kundi, Muzaffer Ari, Ferhat Bozkus
Nasopharynx (NP) is anatomically difficult to explore adequately. The pharyngeal bursa (PB) is a recess lined with respiratory epithelium along the posterior wall of the nasopharynx between the longus capitis muscles. If the opening through which the bursa drains into the nasopharynx becomes obstructed, a Thornwaldt's cyst (TC) might develop. Small-sized cysts are mostly asymptomatic, whereas large-sized cysts may lead to various nasal and otologic symptoms depending on their localization. In this report, we present a 71-year-old case with a huge TC who presented to our clinic with the complaints of snoring, nasal obstruction, periodic halitosis, postnasal drip, headache, and hearing loss in the left ear and underwent total excision of the cyst through transnasal endoscopy...
March 2017: JPMA. the Journal of the Pakistan Medical Association
Esther Amstad, Frans Spaepen, Michael P Brenner, David A Weitz
Many powders employed in the food and pharmaceutical industries are produced through spray drying because it is a cost efficient process that offers control over the particle size. However, most commercially available spray-driers cannot produce drops with diameters below 1 μm, limiting the size of spray-dried particles to values above 300 nm. We recently developed a microfluidic spray-drier that can form much smaller drops than commercially available spray-driers. This is achieved through a two-step process: first, the microfluidic spray-drier operates in the dripping regime to form 100 μm diameter primary drops in air and, second, subjects them to high shear stresses due to supersonic flow of air to break them into many much smaller secondary drops...
March 15, 2017: Lab on a Chip
K Schröder, D Finis, S Meller, B A Buhren, M Wagenmann, G Geerling
Seasonsal allergic conjunctivitis (SAC) and perennial allergic conjunctivitis (PAC) as well as intermittent and persistent allergic rhinitis are widespread diseases. Because a combined occurrence of ocular and nasal symptoms is very common the summarising term allergic rhinoconjunctivitis is frequently used. SAC and PAC representing the two acute forms of allergic conjunctivitis account for more than 90% of all cases of allergic conjunctivitis. Compared to the chronic forms of allergic conjunctivitis their course of disease is milder...
February 2017: Laryngo- Rhino- Otologie
Anita L Sikes, Robin Jacob, Bruce D'Arcy, Robyn Warner
The aim of this study was to gain a better understanding of the tenderisation mechanism associated with very fast chilling (VFC) of beef muscle. Hot-boned striploins from 36 carcasses were allocated to a treatment (control, delayed or immediate chilling below 0°C), and each striploin was divided into three equal portions and allocated to a time post-mortem (2, 5 or 14d). Immediate chilling resulted in lower peak force values at 2d post-mortem and lower particle size after 5d post-mortem. Both chilling treatments significantly improved the WHC by reducing drip loss and cooking loss...
March 2017: Food Research International
Ali Fares, Adam Bensley, Haimanote Bayabil, Ripendra Awal, Samira Fares, Hector Valenzuela, Farhat Abbas
Soil moisture and organic matter level affects soil respiration and microbial activities, which in turn impact greenhouse gas (GHG) emissions. This study was conducted to evaluate the effect of irrigation levels (75% [deficit], 100% [full], and 125% [excess] of reference crop evapotranspiration requirements), and organic amendments (OA) type (chicken manure [CM] and bone meal [BM]) and OA application rates (0,168, 336 and 672 kg total N ha(-1)) on (i) soil physical properties (bulk density, organic matter content and soil moisture content) and (ii) soil carbon dioxide (CO2) emissions from a highly weathered tropical Hawai'ian soil...
March 3, 2017: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
Y Chen, H Chen, W Li, J Miao, N Chen, X Shao, Y Cao
Polyphenols in Eucalyptus leaves (PE) were value resources due to various pharmacological activities, but data on the effect on laying hens are very scare. This study was conducted to determine the effect of PE on the laying performance, egg traits, meat quality, antioxidant status and liver tissues of laying hens. One hundred and twenty 256-day-old Yueqinhuang laying hens were randomly assigned to four treatment groups (different levels of PE at 0, 0.5, 0.8 and 1.2 g/kg diet) for 63 days with 15 replicates per group...
March 9, 2017: Journal of Animal Physiology and Animal Nutrition
Eizo Watanabe, Shingo Yamazaki, Daisuke Setoguchi, Tomohito Sadahiro, Yoshihisa Tateishi, Tatsuya Suzuki, Itsuko Ishii, Shigeto Oda
INTRODUCTION: Recombinant human soluble thrombomodulin (rTM) is reportedly excreted by the kidneys; therefore, the recommended dose for patients with renal impairment is one-third of the standard dose. The aim of this study was to evaluate whether this reduced dose of rTM achieves effective drug concentrations that are comparable to those of the standard dose in treating sepsis-induced disseminated intravascular coagulation (DIC) during continuous hemodiafiltration (CHDF). METHODS: Eight patients in an intensive care unit were randomized to receive either reduced-dose (0...
2017: Frontiers in Medicine
Jueying Qian, Harald Horn, Jorge Tarchitzky, Yona Chen, Sagi Katz, Michael Wagner
Drip irrigation is a water-saving technology. To date, little is known about how biofilm forms in drippers of irrigation systems. In this study, the internal dripper geometry was recreated in 3-D printed microfluidic devices (MFDs). To mimic the temperature conditions in (semi-) arid areas, experiments were conducted in a temperature controlled box between 20 and 50°C. MFDs were either fed with two different treated wastewater (TWW) or synthetic wastewater. Biofilm formation was monitored non-invasively and in situ by optical coherence tomography (OCT)...
March 2017: Biofouling
T M Ngapo
The aim of this study is to identify the most important characteristics of fresh pork that determine consumer choice in five Canadian provinces. Within-consumer preference replication and systematic image manipulation in surveying showed differences in strategies for pork choice in lean colour (P<0.001) and marbling (P=0.006). High proportions of Nova Scotians (29%) chose light red pork, Albertans (42%) dark red and Quebecers (29%) non-marbled pork. Overall, the most important choice criteria were fat cover (57% preferred lean, 8% fatty) and lean colour (35% dark red, 18% light red)...
February 27, 2017: Meat Science
Justin L Poklis, Haley A Mulder, Matthew S Halquist, Carl E Wolf, Alphonse Poklis, Michelle R Peace
The blue lotus flower (Nymphea caerulea) is an Egyptian water lily containing apomorphine and nuciferine. Apomorphine has been described as a psychoactive alkaloid and is a non-selective dopamine agonist primarily used to treat Parkinson's disease as it stimulates dopamine receptors and improves motor function. Nuciferine is an alkaloid associated with dopamine receptor blockade. Today, blue lotus flower is used as a sleep aid and anxiety reliever. The rebuildable dripping atomizer (RDA) is an electronic cigarette that allows direct application of an e-liquid onto the coil in the atomizer for aerosolization, compared to a typical electronic cigarette where the e-liquid is wicked from a storage vessel to the coil...
March 7, 2017: Journal of Psychoactive Drugs
Jun Ni, Jiazhi Qu, Ming Yao, Zhijun Zhang, Xihua Zhong, Liying Cui
Acute ischemic stroke (AIS) is a major medical challenge in China. Thrombolytic drugs recommended for the treatment of AIS usually have a narrow time window. Human urinary kallidinogenase (HUK) was approved by the China Food and Drug Administration (CFDA) in 2005 for the treatment of mild to moderate AIS, and it is thus widely used in China. However, large-scale clinical study data for a more complete understanding of various aspects of its safety and efficacy characteristics are still unavailable. The ongoing Reevaluate the Efficacy and Safety of Human Urinary Kallidinogenase (RESK) trial is designed to reevaluate the safety and efficacy of HUK in Chinese patients with AIS...
March 6, 2017: Translational Stroke Research
Wen Sang, Zeng-Rong Huang, Lin-Tong Yang, Peng Guo, Xin Ye, Li-Song Chen
Citrus are sensitive to boron (B)-toxicity. In China, B-toxicity occurs in some citrus orchards. So far, limited data are available on B-toxicity-responsive proteins in higher plants. Thirteen-week-old seedlings of "Sour pummelo" (Citrus grandis) and "Xuegan" (Citrus sinensis) was fertilized every other day until dripping with nutrient solution containing 10 μM (control) or 400 μM (B-toxicity) H3BO3 for 15 weeks. The typical B-toxic symptom only occurred in 400 μM B-treated C. grandis leaves, and that B-toxicity decreased root dry weight more in C...
2017: Frontiers in Plant Science
Md Abul Kalam Azad, Tobias Krause, Leon Danter, Albert Baars, Kerstin Koch, Wilhelm Barthlott
Fog collecting meshes show a great potential to ensure the availability of a supply of sustainable fresh water in certain arid regions. In most cases, the meshes are made of hydrophilic smooth fibers. Based on the study of plant surfaces, we analyzed the fog-collection of different polyethylene terephthalate (PET) fibers with different cross-sections and different surface structures with the aim of developing optimized biomimetic fog collectors. Water droplet movement and the onset of dripping from fiber samples were compared...
March 5, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
Masaki Ogawa, Yoshiyuki Ozawa, Kengo Ohta, Tomoya Sekiguchi, Shingo Omata, Misugi Urano, Yoichi Matsuo, Yuta Shibamoto
PURPOSE: For liver surgery, it is crucial to preoperatively examine the course of the right posterior bile duct. While MR cholangiopancreatography (MRCP) can only visualize the bile ducts, 3D balanced turbo-field-echo (BTFE) sequence clearly depicts the bile ducts and portal veins as well as drip infusion CT cholangiography (DIC-CT), without contrast media. We evaluated whether BTFE could substitute for DIC-CT. MATERIALS AND METHODS: Thirty patients undergoing MRCP and BTFE on 1...
March 4, 2017: Abdominal Radiology
Suvi Manner, Darla M Goeres, Malena Skogman, Pia Vuorela, Adyary Fallarero
Biofilm formation leads to the failure of antimicrobial therapy. Thus, biofilm prevention is a desirable goal of antimicrobial research. In this study, the efficacy of antibiotics (doxycycline, oxacillin and rifampicin) in preventing Staphylococcus aureus biofilms was investigated using Microtiter Well Plates (MWP) and Drip Flow Reactors (DFR), two models characterized by the absence and the presence of a continuous flow of nutrients, respectively. Planktonic culture of S. aureus was exposed to antibiotics for one hour followed by 24 hours incubation with fresh nutrients in MWP or continuous flow of nutrients in DFR...
March 2, 2017: Scientific Reports
Sara D'Aronco, Mattia Dall'Armi, Sara Crotti, Eleonora Calandra, Pietro Traldi, Valerio Di Marco, Angela Buonadonna, Giuseppe Corona, Luciana Giodini, Elena Marangon, Bianca Posocco, Giuseppe Toffoli, Marco Agostini
The field-assisted paper spray (FAPS) - mass spectrometric method has been employed to quantify the imatinib (IMT) plasma levels in treated patients. The quantitative measurements have been performed on the collisionally generated fragment at m/z 394 of the protonated molecules of IMT and deuterated imatinib (d3 -IMT), used as internal standard. The FAPS-MS/MS method exhibits some limitations, due to the high number of operative parameters that need to be carefully controlled. For this aim paper supports of different geometry and different thickness and porosity were tested...
March 2, 2017: Journal of Mass Spectrometry: JMS
G Turc
No abstract text is available yet for this article.
April 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
Hua Ma, Helong Wang, Yulan Luo, Shujun Guo, Chuanwang Song
Bronchial asthma is a common chronic airway inflammatory disease. MicroRNAs (miRNAs) play an important role in the pathogenesis of asthma. We have previously shown that miR-20b can inhibit airway inflammation in asthmatic mice, but the exact mechanism is unknown. In the present study, we show that administration of nasal drops containing miR-20b induced an increase in the percentage of Gr1(+)CD11b(+) myeloid-derived suppressor cells (MDSCs) in lung tissue from asthmatic mice, and the content of TGF-β in lung tissues also increased after treatment...
January 2017: Annals of Clinical and Laboratory Science
M Azari-Anpar, N Soltani Tehrani, N Aghajani, M Khomeiri
In this study, effect of Qodume shahri (Lepidium perfoliatum) and cress (Lepidium sativum) on rheological properties of ice cream were investigated. The gums were added to the ice cream formulation and different quality attributes including pH, acidity, melting characteristics, viscosity, overrun, texture analysis and sensory evaluation were determined. Results showed that ice cream formulations containing both the gums had improved overrun, melting rate, first dripping time, viscosity, hardness and adhesiveness...
January 2017: Journal of Food Science and Technology
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