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Ciclosporin or cyclosporine, dog or canine

John P Buchweitz, Douglas Mader, Andreas F Lehner
A case of canine intoxication and fatality with the pyrethroid insecticide bifenthrin is described. A 5-year-old female spayed Pit Bull Terrier was off leash and unsupervised at home for 15-20 min prior to discovery by her owner. The patient was in lateral recumbency, having what the owner described as a seizure. The patient was transported to an emergency veterinary hospital where she presented with tachycardia, tachypnea and intractable tremors/seizures. Despite aggressive medical intervention, the patient went into respiratory and cardiac arrest and died at 28 h after presentation...
July 11, 2018: Journal of Analytical Toxicology
Cesar de Gregorio, Nestor Cohenca, Fabio Romano, Carolina Maschietto Pucinelli, Nathalie Cohenca, Martin Romero, Marilia Pacífico Lucisano, Raquel Assed Bezerra da Silva, Lea Assed Bezerra da Silva
BACKGROUND/AIM: The extra-alveolar dry period and storage medium in which a tooth is kept prior to replantation remain critical factors affecting the survival and repair potential of the periodontal ligament in avulsed teeth. When replantation is not immediate, replacement root resorption (RRR) is the most common complication. The aim of this histological study was to evaluate the effect of immediate controlled-orthodontic forces in periodontal healing of replanted teeth in a canine model...
July 14, 2018: Dental Traumatology: Official Publication of International Association for Dental Traumatology
C Wallis, K V Patel, M Marshall, R Staunton, L Milella, S Harris, L J Holcombe
OBJECTIVES: To determine the incidence and rates of progression of gingivitis and periodontitis in Labrador retrievers. MATERIALS AND METHODS: Fifty-three dogs, aged 1·1 to 5·9 years, had their periodontal health assessed every 6 months for up to 2 years. The extent of gingivitis and periodontitis was measured around the whole gingival margin of every tooth under general anaesthesia. RESULTS: All dogs had gingivitis at the initial assessment...
July 13, 2018: Journal of Small Animal Practice
Gláucia B Pereira-Neto, Márcio A Brunetto, Patrícia M Oba, Tatiana Champion, Cecilia Villaverde, Thiago H A Vendramini, Julio C C Balieiro, Aulus C Carciofi, Aparecido A Camacho
Canine obesity is a common medical disorder and a known risk factor for associated diseases; it can seriously influence various physiological functions, thereby limiting the longevity of the animal. In this study, we evaluated potential respiratory alterations in obese dogs before and after being subjected to caloric restriction to decrease their body weight by 20%, and compared those dogs with control dogs with ideal body condition score. The animals were divided into three experimental groups: GI (obese dogs; n = 11); GII (obese dogs after weight loss, same animals as in GI); GIII (control dogs; n = 11)...
July 13, 2018: Journal of Animal Physiology and Animal Nutrition
Yoshifumi Nishikawa, Naomi Shimoda, Ragab M Fereig, Tomoya Moritaka, Kousuke Umeda, Maki Nishimura, Fumiaki Ihara, Kaoru Kobayashi, Yuu Himori, Yutaka Suzuki, Hidefumi Furuoka
Neospora caninum is a protozoan parasite closely related to Toxoplasma gondii Neosporosis caused by N. caninum is considered one of the main causes of abortion in cattle and nervous-system dysfunction in dogs, and identification of the virulence factors of this parasite is important for the development of control measures. Here, we used a luciferase reporter assay to screen the dense granule proteins genes of N. caninum , and found that NcGRA6, NcGRA7, and NcGRA14 are involved in the activation of the NF-κB, calcium/calcineurin, and cAMP/PKA signals...
July 13, 2018: Applied and Environmental Microbiology
Jan Tkadlec, Marcela Krutova, Jana Matejkova, Otakar Nyc, Pavel Drevinek
Bacteroides pyogenes can cause infections in humans. We describe a case of bloodstream infection caused by Bacteroides denticanum that probably originated from a dog bite. MALDI-TOF MS misidentified this new species as B. pyogenes. Subsequent analysis using the 16S rRNA sequencing approach identified the species as B. denticanum.
July 10, 2018: Anaerobe
Shuang Mei, Fusheng Dong, Mohammad Sayedur Rahman Khan
PURPOSE: The purpose of this study was to investigate the effect of a biologically active dental implant surface (treated with sandblasting and acid etching [SLA] followed by immersion in simulated body fluid [SBF]) on osseointegration. MATERIALS AND METHODS: We randomly divided 9 healthy adult male beagles (aged 8 months; body weight, 12 kg) into 3 groups: machined, SLA, and SLA-biomineralization (SLA-Bio). Six pure titanium implants (diameter of 3.5 mm and length of 8 mm) were used in the mandible of each dog after observation of the surface morphology, as well as analysis of the composition of the surface elements by scanning electron microscopy-energy dispersive x-ray spectroscopy...
June 18, 2018: Journal of Oral and Maxillofacial Surgery
Jean-Philippe Ré, Jean-Daniel Orthlieb
No abstract text is available yet for this article.
July 10, 2018: Journal of Prosthetic Dentistry
Elisabetta Zanatta, Pamela Polito, Mariangela Favaro, Maddalena Larosa, Piero Marson, Franco Cozzi, Andrea Doria
Scleroderma renal crisis (SRC) is an uncommon but still life-threatening manifestation of systemic sclerosis (SSc). The incidence of SRC has decreased in the last few decades, probably due to a widespread use of vasodilators in SSc patients. It is well-recognized that exposure to different drugs can trigger SRC (corticosteroids, cyclosporine) or prevent its occurrence (iloprost, calcium channel blockers). The prognosis of this life-threatening manifestation has not substantially improved since 1980s, when ACE-inhibitors were introduced in its treatment...
July 10, 2018: Autoimmunity Reviews
Florence Cliquet, Anne-Laure Guiot, Michel Aubert, Emmanuelle Robardet, Charles E Rupprecht, François-Xavier Meslin
The mass vaccination of dogs is a proven tool for rabies prevention. Besides parenteral delivery of inactivated vaccines, over the past several decades, several self-replicating biologics, including modified-live, attenuated and recombinant viruses, have been evaluated for the oral vaccination of dogs against rabies. Vaccines are included within an attractive bait for oral consumption by free-ranging dogs. Due to the high affinity between dogs and humans, such biologics intended for oral vaccination of dogs (OVD) need to be efficacious as well as safe...
July 13, 2018: Veterinary Research
Romolo Caniglia, Elena Fabbri, Pavel Hulva, Barbora Černá Bolfíková, Milena Jindřichová, Astrid Vik Stronen, Ihor Dykyy, Alessio Camatta, Paolo Carnier, Ettore Randi, Marco Galaverni
BACKGROUND: Genomic methods can provide extraordinary tools to explore the genetic background of wild species and domestic breeds, optimize breeding practices, monitor and limit the spread of recessive diseases, and discourage illegal crossings. In this study we analysed a panel of 170k Single Nucleotide Polymorphisms with a combination of multivariate, Bayesian and outlier gene approaches to examine the genome-wide diversity and inbreeding levels in a recent wolf x dog cross-breed, the Czechoslovakian Wolfdog, which is becoming increasingly popular across Europe...
July 13, 2018: BMC Genomics
Michele Losurdo, Giulia Dowgier, Maria Stella Lucente, Mario Cinone, Michele Camero, Maria Loredana Colaianni, Giuseppe Passantino, Gianluca Ventriglia, Domenico Buonavoglia, Nicola Decaro
The long-term shedding of Canine alphaherpesvirus 1 (CaHV-1) by neonatal pups with natural infection is reported. The pups belonged to a litter of 11 pointers of a breeding kennel in southern Italy, 9 of which developed a fatal form of systemic infection, as resulted by the detection of CaHV-1 in internal organs (kidney, liver, lung and brain) of one of this dogs and in the vaginal swab of their mother. The two remaining animals displayed a milder form of disease, with one pup showing ocular involvement, and underwent a progressive recovery...
July 6, 2018: Research in Veterinary Science
Chris Degeling, Victoria Brookes, Tess Lea, Michael Ward
Australia is currently canine rabies free; however, the spread of rabies in eastern Indonesia poses an increasing risk to northern Australia. Domestic dogs are numerous in East Arnhem Land (EAL) and the Northern Peninsular Area (NPA), usually unrestrained and living in close relationships with humans. The response to any rabies outbreak on Australian territory will focus on dog vaccination, controlling dog movements and depopulation. A One Health approach to zoonotic disease control should seek to co-promote human and animal health, whilst also seeking to accommodate the preferences of affected communities...
July 5, 2018: Social Science & Medicine
Rashan Haniffa, Abi Beane, Arjen M Dondorp
No abstract text is available yet for this article.
August 2018: Critical Care Medicine
John S Clemmer, William Andrew Pruett, Robert L Hester, Radu Iliescu, Thomas E Lohmeier
Electrical stimulation of the baroreflex chronically suppresses sympathetic activity and arterial pressure and is currently being evaluated for the treatment of resistant hypertension. The antihypertensive effects of baroreflex activation are often attributed to renal sympathoinhibition. However, baroreflex activation also decreases heart rate, and robust blood pressure lowering occurs even after renal denervation. Because controlling renal sympathetic nerve activity and cardiac autonomic activity cannot be achieved experimentally, we used an established mathematical model of human physiology (HumMod) to provide mechanistic insight into their relative and combined contributions to the cardiovascular responses during baroreflex activation...
July 13, 2018: American Journal of Physiology. Heart and Circulatory Physiology
Ali Raza, Jacquie Rand, Abdul Ghaffar Qamar, Abdul Jabbar, Steven Kopp
Dogs entering shelters can carry gastrointestinal parasites that may pose serious risks to other animals, shelter staff and visitors. Shelters provide an environment that could facilitate the spread of parasitic infections between animals. Nematodes and protozoa that transmit through ingestion or skin penetration are major enteric parasites of concern in shelter settings. Ancylostoma spp., Uncinaria stenocephala , Toxocara canis , Toxascaris leonina , Trichuris vulpis and Dipylidium caninum are the major helminths while Giardia , Cryptosporidium , Isospora spp...
July 2, 2018: Animals: An Open Access Journal From MDPI
Bence Varga, Anna Gergely, Ágoston Galambos, Anna Kis
The domestic dog ( Canis familiaris ) has been shown to both excel in recognising human emotions and produce emotion-related vocalisations and postures that humans can easily recognise. However, little is known about the effect of emotional experiences on subsequent sleep physiology, a set of phenomena heavily interrelated with emotions in the case of humans. The present paper examines heart rate (HR) and heart rate variability (HRV) during dogs' sleep, measures that are influenced by both positive and negative emotions in awake dogs...
July 2, 2018: Animals: An Open Access Journal From MDPI
Luiz H S Tavares, Dennis de C Ferreira, Antonieta de Q Côrtes, Andréia G Machado, Ernani da C Abad, Eduardo J V Lourenco, Lucio S Gonçalves
AIM: The aim of the present study was to assess the association of sex, age, group of teeth, and type of accident (exposure) with dental fractures (outcome: enamel-dentine fracture without [EDF] or with pulp exposure [EDPF] and root fracture RF]). METHODS: In total, 1046 patients were selected. Logistic binary regression was used. RESULTS: The findings showed that EDF has less change of affecting individuals ≤9 years of age than ≥40 years of age (odds ratio [OR]: 0...
July 13, 2018: Journal of Investigative and Clinical Dentistry
Charles Boucher, Maryke M Henton, Piet J Becker, Robert M Kirberger, Marthinus J Hartman
OBJECTIVE: To compare the antimicrobial efficacy of a 2% chlorhexidine gluconate and 70% ethanol solution (CG+A) with that of F10 Skin Prep Solution (F10) and electrochemically activated water (EAW) when used as a surgical preparation in canine patients. STUDY DESIGN: Prospective randomized clinical study. SAMPLE POPULATION: One hundred sixteen dogs presented for ovariohysterectomy. METHODS: Dogs were randomly divided into 1 of the 3 antiseptic groups (CG+A, F10, EAW)...
July 13, 2018: Veterinary Surgery: VS
Ruenruetai Udonsom, Rapeepan Prasertbun, Aongart Mahittikorn, Hirotake Mori, Tanasak Changbunjong, Chalit Komalamisra, Ai-Rada Pintong, Yaowalark Sukthana, Supaluk Popruk
Blastocystis spp. are common gastrointestinal parasites of humans and a variety of animals, with various host-specific subtypes. The aim of this study was to determine the prevalence of Blastocystis infection and identify subtypes in humans and domestic animals. One hundred and thirteen stool samples were collected from pigs, goats, and cattle in Ayutthaya Province (AP; central Thailand) and 218 stool samples were collected from pigs, dogs, cats, chickens, and humans in Kanchanaburi Province (KP; western Thailand)...
July 9, 2018: Infection, Genetics and Evolution
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