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https://www.readbyqxmd.com/read/30439704/multiple-congenital-anomalies-and-global-developmental-delay-in-a-patient-with-interstitial-6q25-2q26-deletion-a-diagnostic-odyssey
#1
Prabakaran Paulraj, Janice C Palumbos, Amanda Openshaw, John C Carey, Reha M Toydemir
Interstitial deletions involving 6q25 are rare chromosomal abnormalities associated with distinctive phenotypic features. We describe a 9-year-old boy who was followed from his infancy due to his multiple congenital anomalies and complex medical history. Over the years, a number of diagnoses were considered including Cornelia de Lange syndrome, Rubinstein-Taybi syndrome, as well as "a novel genetic disorder." Various genetic tests, including a BAC-based array-CGH analysis, were reported as normal...
November 16, 2018: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/30439311/-risk-factors-and-etiological-analysis-of-ventilator-associated-pneumonia-three-year-s-cases-analysis-of-intensive-care-unit-in-county-hospital
#2
Zhicheng Hu, Shusheng Zhou
OBJECTIVE: To investigate the risk factors of ventilator-associated pneumonia (VAP) and the distribution and drug resistance of pathogens in intensive care unit (ICU) of county hospital. METHODS: 234 patients on mechanical ventilation for more than 48 hours admitted to ICU of Shexian People's Hospital of Huangshan City from January 2016 to June 2018 were enrolled. The clinical data of all patients including gender, age, past medical history, exposure to antibiotics, medication, the duration of mechanical ventilation, the length of ICU stay, serum albumin, tracheotomy, re-intubation, prognosis, and pathogenic bacteria and drug sensitivity test of VAP patients were collected...
October 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/30433817/impact-of-diet-on-the-incidence-of-cataract-surgery-among-diabetic-patients-findings-from-the-45-and-up-study
#3
Changfan Wu, Xiaotong Han, Xixi Yan, Stuart Keel, Xianwen Shang, Lei Zhang, Mingguang He
OBJECTIVE: To examine the impact of diet on the incidence of cataract surgery among the working-aged diabetic population in Australia. METHODS: This cohort study was conducted among 8,752 participants with diabetes aged 45-65 years who were recruited to the 45 and Up Study from 2006 to 2016. The data was linked to the Medicare Benefits Schedule (MBS) to obtain data on cataract surgery. Diabetes was defined as self-reported on questionnaire or diabetes medication history based on Pharmaceutical Benefits Scheme (PBS)...
November 15, 2018: Current Eye Research
https://www.readbyqxmd.com/read/30431667/biliary-papillomatosis
#4
Mathieu Struyve, Schalk Van Der Merwe
A 74-year-old asymptomatic man was referred to the outpatient clinic by his general practitioner because of abnormal liver enzymes. He had no important medical history. Blood analysis showed mild cholestasis. Abdominal computed tomography showed bile duct dilatation with contrast capturing mural nodules in the common bile duct with protrusion into the dilated lumen (Figure 1a). Magnetic resonance cholangiopancreaticography revealed bile duct dilatation with multiple irregular filling defects (Figure 1b). This article is protected by copyright...
November 15, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/30430492/about-a-lymphoepithelioma-like-carcinoma-of-the-lung-with-an-endotracheal-localization
#5
Mona Mlika, Besma Hamdi, Adel Marghli, Faouzi El Mezni
INTRODUCTION: Lympho-epithelioma like carcinoma is a rare lung tumour that acounts for less than 1% of non small cell lung carcinomas. It is defined as a special entity among the 2015 World Health Organization. AIM: Our aim was to describe a completely illustrated new case of lymhpo-epithelioma like carcinoma. We describe a new case diagnosed in our Department of Pathology. CASE PRESENTATION: The authors describe a case of a 22-year-old woman without a particular past medical history who presented non specific respiratory symptoms...
July 2018: La Tunisie Médicale
https://www.readbyqxmd.com/read/30430050/right-ventricular-outflow-obstruction-due-to-metastatic-neuroendocrine-tumor
#6
Akhil Sood, Simbo M Chiadika, Jamie M Everett, Jason Au, Julie Rowe
Neuroendocrine tumors (NETs) are rare malignant tumors that arise from neuroendocrine cells of the gastrointestinal tract and often metastasize to the liver, lung, and bone. Cardiac metastasis of NETs is uncommon. We report a patient with a past medical history of a neuroendocrine tumor of the left femur presenting with signs and symptoms of new onset heart failure. Transthoracic echocardiogram and cardiac magnetic resonance showed a large mass within the right ventricle causing right ventricular outflow obstruction...
September 6, 2018: Curēus
https://www.readbyqxmd.com/read/30429924/obtaining-history-with-a-language-barrier-in-the-emergency-department-perhaps-not-a-barrier-after-all
#7
Megan Litzau, Joseph Turner, Katie Pettit, Zachary Morgan, Dylan Cooper
Introduction: Patients with limited English proficiency may be at risk for incomplete history collection, potentially a patient safety issue. While federal law requires qualified medical interpreters be provided for these patients, little is known about the quality of information obtained in these encounters. Our study compared the medical histories obtained by physicians in the emergency department (ED) based on whether the patients primarily spoke English or Spanish. Methods: This was a prospective, observational study conducted at a single, urban, academic ED during a six-month time period...
November 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/30429731/emergency-department-visits-for-paroxysmal-supraventricular-tachycardia-in-saudi-arabia
#8
Saqer M Althunayyan, Anas A Khan, Osama A Samarkandi
Purpose: The present study aimed to compare the demographic, medical history, clinical features, and treatment management of paroxysmal supraventricular tachycardia (PSVT) in the emergency department of a teaching hospital in Riyadh, Saudi Arabia. A secondary purpose was to evaluate Adenosine response among numerous variables that might be used as predictors of the conversion. Methods: All PSVT cases presented to the Department of Emergency Medicine at King Khalid University Hospital, during the period from January 1, 2016, until December 31, 2016, were included in the study...
October 2018: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/30428967/the-importance-of-dental-screening-prior-to-commencing-anti-resorptive-therapy-for-treatment-of-cancer-a-case-report-and-discussion
#9
Fiona McDonnell, Clare Steel
Osteonecrosis of the jaws (ONJ) can be a serious complication of radiation and anti-resorptive therapies. At present, patients due to undergo radiotherapy are required to have a dental assessment to treat current or anticipated dental disease prior to commencing treatment. However no agreed guidelines are in place for those due to start anti-resorptive therapy for cancer. More patients are now being treated with various drug therapies and new combinations of drugs with unknown long-term effects, with many patients now surviving their disease for longer periods of time...
September 1, 2018: Primary Dental Journal
https://www.readbyqxmd.com/read/30428951/patient-predictors-of-surgical-candidacy-in-elective-spine-disorders
#10
Michael M H Yang, Godefroy Hardy St-Pierre, Stephan DuPlessis
BACKGROUND: The expansion of age-related degenerative spine pathologies has led to increased referrals to spine surgeons. However, the majority of patients referred for surgical consultation do not need surgery, leading to inefficient use of healthcare resources. This study aims to elucidate preoperative patient variables that are predictive of patients being offered spine surgery. METHODS: We conducted an observational cohort study on patients referred to our institution between May 2013 and January 2015...
November 15, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/30428871/shift-work-and-cognitive-impairment-in-later-life-results-of-a-cross-sectional-pilot-study-testing-the-feasibility-of-a-large-scale-epidemiologic-investigation
#11
Tobias Weinmann, Céline Vetter, Susanne Karch, Dennis Nowak, Katja Radon
BACKGROUND: The effect of shift work on impairment of cognition in later life has not yet been sufficiently investigated. Therefore, we aimed at testing the feasibility of a large-scale epidemiologic study examining this putative association in a pilot study. METHODS: Between January and April 2017, a cross-sectional study invited a random sample of 425 former and current employees of a German university hospital aged 55 years and older to undergo a cognitive test battery (including the Repeatable Battery for the Assessment of Neuropsychological Status, Trail Making Test, Letter-Number Span, and Vocabulary Test) and to complete a self-administered questionnaire on socio-demographic characteristics, chronotype, sleep, occupational history including shift work, and medical history...
November 14, 2018: BMC Public Health
https://www.readbyqxmd.com/read/30428740/diagnostic-pitfalls-in-ovarian-androgen-secreting-leydig-cell-tumours-case-series
#12
M Fanta, D Fischerová, T Indrielle-Kelly, P Koliba, A Zdeňková, A Burgetová, J Vrbíková
Leydig cell tumours of the ovary are rare and represent a diagnostic challenge not only due to their sporadic incidence but also due to the seemingly normal imaging. We present three cases of pre- and postmenopausal women who were presented with severe clinical signs of hyperandogenism where modern imaging modalities (including computed tomography (CT), magnetic resonance imaging (MRI) and positron-emission tomography combined with computed tomography (PET-CT)) failed to identify the tumour. Two patients underwent non-expert ultrasound, CT and MRI examination with uniform conclusion that ovaries are of normal appearance...
November 14, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/30428496/hypoglycemia-and-glucagon-utilization-in-insulin-treated-diabetic-patients
#13
Marino Vilovic, Tina Ticinovic Kurir, Anela Novak, Mladen Krnic, Josip Andelo Borovac, Ivan-Kresimir Lizatovic, Visnja Kokic, Josko Bozic
BACKGROUND: First choice of therapy for severe hypoglycemia outside hospital environment is glucagon injection, an undertaught and underused remedy. Aim of this study was to investigate knowledge about glucagon therapy, possession rate and usage rate in insulin-treated diabetic patients, with special emphasis on history of hypoglycemia and severe hypoglycemia episodes. METHODS: In this cross-sectional study, 300 insulin-treated diabetic patients (146 males and 154 females, mean age 61...
November 14, 2018: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/30428469/high-prevalence-of-pathological-hydrogen-breath-tests-in-patients-with-functional-dyspepsia
#14
Golo Petzold, Ahmad Amanzada, Thomas M Gress, Volker Ellenrieder, Albrecht Neesse, Steffen Kunsch
BACKGROUND/AIMS: The aim of the study is to investigate the frequency of pathological hydrogen breath tests (HBT) in patients with clinical features of functional dyspepsia (FD) meeting the Rome criteria and normal testing of upper endoscopy and abdominal sonography. METHODS: We retrospectively included patients who underwent HBT (lactose, fructose, or glucose) between 2006 and 2012 and who had symptoms of FD. Patients were divided into 2 groups according to medical history and diagnostic results: (I) patients with suspected FD according to the Rome III criteria and (II) patients with an alternative diagnosis such as gastroesophageal reflux disease (GERD) or Crohn's disease (CD)...
November 14, 2018: Digestion
https://www.readbyqxmd.com/read/30428150/reduction-of-computed-tomography-use-for-pediatric-closed-head-injury-evaluation-at-a-non-pediatric-community-emergency-department
#15
Melissa S Puffenbarger, Fahd A Ahmad, Michelle Argent, Hongjie Gu, Charles Samson, Kimberly S Quayle, Jacqueline M Saito
OBJECTIVE: The purpose of this study was to determine if implementation of a Pediatric Emergency Care Applied Research Network (PECARN)-based closed head injury assessment tool could safely decrease computed tomography (CT) use for pediatric head injury evaluation at a non-pediatric community emergency department (ED). METHODS: A quality improvement project was initiated at a non-pediatric community ED to implement an institution-specific, Pediatric Emergency Care Applied Research Network (PECARN)-based Pediatric Closed Head Injury Assessment Tool...
November 14, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/30426881/unusual-metastatic-localization-to-the-kidney-of-basaloid-squamous-cell-carcinoma-of-the-oropharynx
#16
Costantino Ricci, Martina S Rossi, Roberta De Stefano, Michelangelo Fiorentino, Francesco Vasuri
CASE PRESENTATION: A 55-year-old man with a history of basaloid squamous cell carcinoma of the oropharynx with laterocervical lymph node metastases 6 years before (and treated with chemoradiation) presented with flank pain and hematuria. Computed tomography scan found a renal lesion, with radiological features more suspicious for primitive renal neoplasia. Histopathological and immunohistochemical examination after surgical excision revealed a basaloid squamous cell carcinoma involving renal parenchyma...
November 2018: Urologia
https://www.readbyqxmd.com/read/30426880/risk-factors-for-urethral-stricture-and-or-bladder-neck-contracture-after-monopolar-transurethral-resection-of-the-prostate-for-benign-prostatic-hyperplasia
#17
Anton Grechenkov, Roman Sukhanov, Eugene Bezrukov, Denis Butnaru, Guido Barbagli, Igor Vasyutin, Alexander Tivtikyan, Leonid Rapoport, Yury Alyaev, Peter Glybochko
OBJECTIVE: To identify risk factors for urethral stricture and/or bladder neck contracture after transurethral resection of benign prostatic hyperplasia. MATERIALS AND METHODS: We performed a retrospective analysis of 402 patients, which underwent a monopolar transurethral resection of the prostate in the urology clinic of Sechenov First Moscow State Medical University for prostatic hyperplasia during the period 2011-2014. Urethral stricture and (or) bladder neck contracture in the postoperative period were diagnosed in 61 (15...
November 2018: Urologia
https://www.readbyqxmd.com/read/30426578/prediction-of-adverse-perinatal-outcomes-by-the-cerebroplacental-ratio-in-women-undergoing-induction-of-labour
#18
Magdalena Fiolna, Vira Kostiv, Christos Anthoulakis, Ranjit Akolekar, Kypros H Nicolaides
OBJECTIVE: To investigate the performance of screening for adverse perinatal outcome by the cerebroplacental ratio (CPR) measured within 24 hours of induction of labor. METHODS: This was a prospective observational study in 1,902 singleton pregnancies undergoing induction of labor at ≥ 37 weeks' gestation. Doppler ultrasound was used to measure the pulsatility index (PI) in the umbilical artery (UA) and fetal middle cerebral artery (MCA) before induction of labor...
November 13, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/30426394/mini-incision-open-appendectomy-with-incision-skin-tissue-retractor-vs-laparoscopic-appendectomy-a-retrospective-study-of-the-management-of-child-acute-appendicitis
#19
Xian-Ling Li, Qin-Ming Zhang, Wei-Ping Zhang, Ting-Ting Liu
INTRODUCTION: This study aims to compare the clinical effects of an incision skin tissue retractor for mini-incision open appendectomy and laparoscopic surgery for pediatric appendicitis. METHODS: From January 2014 to July 2017, a total of 248 patients were included in the present study. Laparoscopic appendectomy was performed for 108 cases (LA group), and mini-incision open appendectomy with an incision skin tissue retractor was performed for 140 cases (MOA-ISTR group)...
November 13, 2018: Advances in Therapy
https://www.readbyqxmd.com/read/30426078/late-presentation-of-a-9-mm-bullet-in-the-ureteropelvic-junction-causing-acute-renal-failure-in-a-solitary-functioning-left-kidney
#20
Hasan Jhaveri, Michael D'Angelo
Background: Urinary obstruction as a result of a late complication of a gunshot wound is rarely reported. Bullet shell fragments may migrate from their initial location into an area causing obstruction. In this study, we present a case of a left renal calculus surrounding a 9 mm gun shell in a patient with a solitary functioning left kidney. Case Presentation: A 53-year-old man presented with left hydronephrosis found on an urgent CT scan following complaints of left flank pain and signs of acute renal failure 10 years after suffering a gunshot wound to the abdomen...
2018: Journal of Endourology Case Reports
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