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https://www.readbyqxmd.com/read/29783271/mid-term-clinical-outcome-and-reconstruction-of-posterior-tibial-slope-after-uka
#1
Alois Franz, Christoph Kolja Boese, Andrej Matthies, Jörg Leffler, Christian Ries
Unicompartmental knee arthroplasty (UKA) has gained growing popularity over the last decades. The posterior tibial slope (PTS) has been shown to play a significant role for knee biomechanics and is thought to be crucial for clinical function of the UKA. We evaluated the clinical outcome at mid-term follow-up after UKA. Furthermore, the reconstruction of the individual PTS was analyzed. A total of 91 consecutive patients undergoing medial UKA for osteoarthritis were included. Patients were contacted by telephone for a survival analysis at a minimum of 30 months after surgery...
May 21, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29782942/effects-of-light-and-dark-phase-testing-on-the-investigation-of-behavioural-paradigms-in-mice-relevance-for-behavioural-neuroscience
#2
Juliet Richetto, Marcello Polesel, Ulrike Weber-Stadlbauer
Different timing and light phases are critical factors in behavioural neuroscience, which can greatly affect the experimental outcomes of the performed tests. Despite the fact that time of testing is one of the most common factors that varies across behavioural laboratories, knowledge about the consequences of testing time on behavioural readouts is limited. Thus, in this study we systematically assessed the effect of this factor on the readout of a variety of elementary and recurrent behavioural paradigms in C57Bl/6 mice...
May 18, 2018: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/29781937/body-composition-assessment-in-female-national-collegiate-athletic-association-division-i-softball-athletes-as-a-function-of-playing-position-across-a-multiyear-time-frame
#3
Ashley Peart, Danielle Wadsworth, Jessica Washington, Gretchen Oliver
Peart, A, Wadsworth, D, Washington, J, and Oliver, G. Body composition assessment in female National Collegiate Athletic Association division I softball athletes as a function of playing position across a multiyear time frame. J Strength Cond Res XX(X): 000-000, 2018-The purpose of this study was to record changes in total body mass, lean body mass (LBM), fat mass (FM), and body fat percentage (BF%) in female National Collegiate Athletic Association (NCAA) Division I level softball athletes over a multiyear time frame using dual-energy x-ray absorptiometry (iDXA)...
May 17, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29781921/exercise-periodization-over-the-year-improves-metabolic-syndrome-and-medication-use
#4
Felix Morales-Palomo, Miguel Ramirez-Jimenez, Juan Fernando Ortega, Ricardo Mora-Rodriguez
PURPOSE: We aimed to determine if yearly repeated exercise training reduces metabolic syndrome (MetS) and the use of medicines to control MetS components. METHODS: Fifty five MetS individuals were randomized into a TRAIN group that underwent two yearly programs of 16-week of high intensity interval training (HIIT) or a non-exercising CONT group. We measured the evolution of all five MetS components, cardiorespiratory fitness (CRF; assessed by VO2PEAK) and medicine use, at baseline (0 months), mid (12 months) and end-point (24 months)...
May 2, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29781788/a-review-of-the-reliability-of-biomechanical-variables-produced-during-the-isometric-mid-thigh-pull-and-isometric-squat-and-the-reporting-of-normative-data
#5
Claire J Brady, Andrew J Harrison, Thomas M Comyns
The use of isometric strength testing, particularly the isometric mid-thigh pull (IMTP) has increased dramatically over the last decade. The IMTP and isometric squat (ISqT) provide one aspect of performance monitoring with variables such as peak force and rate of force development being derived from the force-time curve. The reliability of some of these variables is conflicting in the literature, and the reporting of the reliability is not standardised across the research. The majority of research only reports intraclass correlation coefficients with very few studies reporting coefficient of variation and 90% confidence intervals...
May 21, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29780464/a-first-principles-prediction-on-the-healing-effect-of-graphene-preventing-carrier-trapping-near-the-surface-of-metal-halide-perovskites
#6
W-W Wang, J-S Dang, R Jono, H Segawa, M Sugimoto
We herein report that surface modification of metal halide perovskites using graphene would be beneficial to improving the energy conversion efficiencies of perovskite solar cells. The present first-principles calculations on MAPbI3 with a single vacancy created by removing either I, Pb or MA show that the I and Pb vacancies near the surface result in the formation of Pb-Pb and I-I dimers, respectively. They are predicted to yield mid-gap levels, and would degrade the energy conversion efficiency of perovskite solar cells through carrier trapping...
April 7, 2018: Chemical Science
https://www.readbyqxmd.com/read/29779920/geographic-variation-in-gender-disparities-in-the-us-radiologist-workforce
#7
Andrew B Rosenkrantz, Amy L Kotsenas, Richard Duszak
PURPOSE: To assess geographic variation in gender disparities in the US radiologist workforce. METHODS: Gender, location, and practice affiliation of all radiologists and gender of all nonradiologists were identified for all providers listed in the Medicare Physician Compare database. Variation in female representation among radiologists was summarized at state, county, and individual practice levels, and associations with a variety of county-level population characteristics were explored...
May 17, 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29779821/clinical-efficacy-and-feasibility-of-whey-protein-isolates-supplementation-in-malnourished-peritoneal-dialysis-patients-a-multicenter-parallel-open-label-randomized-controlled-trial
#8
Sharmela Sahathevan, Chee-Hee Se, SeeHoe Ng, Ban-Hock Khor, Karuthan Chinna, Bak Leong Goh, Halim A Gafor, Sunita Bavanandan, Ghazali Ahmad, Tilakavati Karupaiah
BACKGROUND AND AIMS: Poor dietary intake is commonly associated with malnutrition in the dialysis population and oral nutritional supplementation is strategized to redress dietary inadequacy. Knowledge on clinical efficacy of whey protein supplementation (WPS) as an option to treat malnutrition in continuous ambulatory peritoneal dialysis (CAPD) patients is limited. METHODS: This multicenter, parallel, open-label, randomized controlled trial investigated the clinical efficacy of WPS in 126 malnourished CAPD patients with serum albumin <40 g/L and body mass index (BMI) <24 kg/m2 ...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29778864/plaque-morphology-as-predictor-of-late-plaque-events-in-patients-with-asymptomatic-type-2-diabetes-a-long-term-observational-study
#9
David A Halon, Idit Lavi, Ofra Barnett-Griness, Ronen Rubinshtein, Barak Zafrir, Mali Azencot, Basil S Lewis
OBJECTIVES: We used coronary computed tomography angiography (CTA) to determine plaque characteristics predicting individual late plaque events precipitating acute coronary syndromes (ACS) in a cohort of asymptomatic type 2 diabetic patients. BACKGROUND: In patients with coronary artery disease, CTA plaque characteristics may predict mid-term patient events. METHODS: Asymptomatic patients with diabetes 55 to 74 years of age with no history of coronary artery disease (N = 630) underwent baseline 64-slice CTA and detailed plaque level analysis...
May 11, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29777979/a-qualitative-study-of-disengagement-in-disadvantaged-areas-of-the-uk-you-come-through-your-door-and-you-lock-that-door
#10
M Romeo-Velilla, N Ellis, G Hurst, S Grogan, C Gidlow
Health inequalities are a major concern in the UK. Power imbalances are associated with health inequalities and should be challenged through health promotion and empowering strategies, enabling individuals who feel powerless to take control over their own life and act on the determinants of health (Green and Tones, 2010). This study aimed to explore resident expectations of a community engagement programme that intended to empower communities to take action on pre-identified priorities. The programme targeted communities in deprived areas of a mid-sized city in the UK...
May 16, 2018: Health & Place
https://www.readbyqxmd.com/read/29777922/pfoa-and-ulcerative-colitis
#11
Kyle Steenland, Subra Kugathasan, Dana Boyd Barr
INTRODUCTION: PFOA (perfluoroctanoic acid) is a perfluoroalkyl substance (PFAS). Although use in the US has been phased out, PFOA persists indefinitely in the environment, and is present in the serum of virtually all people in industrialized countries. Approximately 6 million Americans drink water comtaminated with PFOA above EPA-recommended levels. In a previous cohort study (n = 32,000), we found a strong positive exposure-response relation between PFOA serum levels and subsequent ulcerative colitis (UC) in a high-exposed population from the mid-Ohio valley, but no association with Crohn's disease...
May 16, 2018: Environmental Research
https://www.readbyqxmd.com/read/29777851/point-of-care-ultrasound-performed-by-a-medical-student-compared-to-physical-examination-by-vascular-surgeons-in-the-detection-of-abdominal-aortic-aneurysms
#12
Trinh Mai, Michael Y Woo, Kim Boles, Prasad Jetty
OBJECTIVE: To determine the test characteristics of point-of-care ultrasonography performed by a medical student versus physical examination by vascular surgeons compared to a gold standard reference scan for the detection of abdominal aortic aneurysms. METHODS: We conducted a prospective, observer-blinded study recruiting patients from an outpatient vascular surgery clinic. Participants were screened for abdominal aortic aneurysms by standardized physical examination by a blinded vascular surgeon, followed by a point-of-care ultrasound examination by a blinded medical student...
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29777582/comparative-study-of-liraglutide-and-insulin-glargine-on-glycemic-control-and-pancreatic-%C3%AE-cell-function-in-db-db-mice
#13
Yanli Li, Jia Zheng, Yunfeng Shen, Wangen Li, Meimei Liu, Jun Wang, Surong Zhu, Meihua Wu
BACKGROUND The aim of this study was to compare the effects of liraglutide, a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist, and insulin glargine, a long-acting insulin analog, on glycemic control and pancreatic β-cell function in db/db mice. MATERIAL AND METHODS Eight-week-old male db/db mice (n=40) were divided into five groups: the vehicle-treated group (VG) (n=8); the insulin glargine-treated group (GG) (dose, 450 mg/kg) (n=8), the low-dose liraglutide-treated group (LLG) (dose, 75 μg/kg) (n=8), the mid-dose liraglutide-treated group (MLG) (150 μg/kg) (n=8), and the high-dose liraglutide-treated group (HLG) (300 μg/kg) (n=8), treated with subcutaneous injection once daily, from 8-14 weeks-of-age...
May 19, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29776723/outcome-of-a-hand-orthosis-and-hand-therapy-for-carpometacarpal-osteoarthritis-in-daily-practice-a-prospective-cohort-study
#14
Jonathan Tsehaie, Kim R Spekreijse, Robbert M Wouters, Harm P Slijper, Reinier Feitz, Steven E R Hovius, Ruud W Selles
PURPOSE: Initial treatment for symptomatic carpometacarpal (CMC) osteoarthritis (OA) of the thumb is usually nonsurgical. However, evidence on the effect of a hand orthosis and hand therapy for mid- and long-term results is limited, and it is unknown how many patients undergo additional surgical treatment. Therefore, the aim of this study is to describe the outcome of a hand orthosis and hand therapy for CMC OA in a large cohort study, and to evaluate the conversion rate to surgical treatment...
May 15, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29776424/impaired-cd8-t-cell-antiviral-immunity-following-acute-spinal-cord-injury
#15
Diana M Norden, John R Bethea, Jiu Jiang
BACKGROUND: Spinal cord injury (SCI) disrupts essential neuroimmune communication, leading to severe immune depression. Previous studies confirmed immune dysfunction in mice with chronic SCI and following high thoracic level injury where sympathetic innervation of the spleen is disrupted. Here, we induced a mid-thoracic injury where integrity of the sympathetic response is maintained and investigated the antiviral T cell response to influenza virus after acute SCI. METHODS: One week following a contusion SCI at thoracic level T9, mice were infected intranasally with influenza virus...
May 17, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29776411/a-study-of-the-factors-associated-with-cervical-spinal-disc-degeneration-with-a-focus-on-bone-metabolism-and-amino-acids-in-the-japanese-population-a-cross-sectional-study
#16
Kanichiro Wada, Toshihiro Tanaka, Gentaro Kumagai, Hitoshi Kudo, Toru Asari, Daisuke Chiba, Seiya Ota, Keita Kamei, On Takeda, Shigeyuki Nakaji, Yasuyuki Ishibashi
BACKGROUND: The physical and biochemical factors responsible for cervical disc degeneration, and resulting in various spinal disorders, remain unclear. This study aimed to evaluate the correlation between cervical spinal canal stenosis and degeneration of intervertebral discs, and to analyze the factors related to disc degeneration in the Japanese population. METHODS: Three hundred and forty-four Japanese general residents underwent investigations, including magnetic resonance imaging of the cervical spine, in our health check project...
May 17, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29775928/tributyltin-impaired-reproductive-success-in-female-zebrafish-through-disrupting-oogenesis-reproductive-behaviors-and-serotonin-synthesis
#17
Wei-Yang Xiao, Ying-Wen Li, Qi-Liang Chen, Zhi-Hao Liu
Tributyltin (TBT), an organotin acting as aromatase (Cyp19a1) inhibitor, has been found to disrupt gametogenesis and reproductive behaviors in several fish species. However, few studies addressing the mechanisms underlying the impaired gametogenesis and reproduction have been reported. In this study, female adults of zebrafish (Danio rerio) were continuously exposed to two nominal concentrations of TBT (100 and 500 ng/L, actual concentrations: 90.8 ± 1.3 ng/L and 470.3 ± 2.7 ng/L, respectively) for 28 days...
May 12, 2018: Aquatic Toxicology
https://www.readbyqxmd.com/read/29775887/gender-and-age-varying-associations-of-sensation-seeking-and-substance-use-across-young-adulthood
#18
Rebecca J Evans-Polce, Megan S Schuler, John E Schulenberg, Megan E Patrick
INTRODUCTION: Sensation seeking is associated with elevated risk for substance use among adolescents and young adults. However, whether these associations vary across age for young men and women is not well characterized. METHODS: Using data from the Monitoring the Future (MTF) panel study, we examine the age-varying associations of sensation seeking and three types of substance use behavior (binge drinking, cigarette use, and marijuana use) across ages 18 to 30 using time-varying effect modeling...
May 4, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29775481/widespread-anatoxin-a-detection-in-benthic-cyanobacterial-mats-throughout-a-river-network
#19
Keith Bouma-Gregson, Raphael M Kudela, Mary E Power
Benthic algae fuel summer food webs in many sunlit rivers, and are hotspots for primary and secondary production and biogeochemical cycling. Concerningly, riverine benthic algal assemblages can become dominated by toxic cyanobacteria, threatening water quality and public health. In the Eel River in Northern California, over a dozen dog deaths have been attributed to cyanotoxin poisonings since 2000. During the summers of 2013-2015, we documented spatial and temporal patterns of cyanotoxin concentrations in the watershed, showing widespread distribution of anatoxin-a in benthic cyanobacterial mats...
2018: PloS One
https://www.readbyqxmd.com/read/29773700/implications-of-involving-pharmacy-technicians-in-obtaining-a-best-possible-medication-history-from-the-perspectives-of-pharmaceutical-medical-and-nursing-staff-a-qualitative-study
#20
Andrea Niederhauser, Chantal Zimmermann, Liat Fishman, David L B Schwappach
OBJECTIVES: In recent years, the involvement of pharmacy technicians in medication reconciliation has increasingly been investigated. The aim of this study was to assess the implications on professional roles and collaboration when a best possible medication history (BPMH) at admission is obtained by pharmacy technicians. DESIGN: Qualitative study with semistructured interviews. Data were analysed using a qualitative content analysis approach. SETTING: Internal medicine units in two mid-sized Swiss hospitals...
May 17, 2018: BMJ Open
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