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https://www.readbyqxmd.com/read/30452214/optimizing-use-and-addressing-challenges-to-uptake-of-biosimilars
#1
Molly Billstein Leber
With the passing and implementation of the Biologics Price Competition and Innovation Act in 2010, biosimilars became a new classification of FDA-approved drugs. The biosimilar classification, created with a streamlined drug approval process, was intended to spur competition and reduce the cost of biological product therapies. Since the first FDA-approved biosimilar in 2015, the impact of biosimilars on the US biological product market remains to be seen. As more biosimilar products are approved and marketed, cost-savings are expected with predictions ranging from $54 billion to $250 billion by the mid-2020s...
November 2018: American Journal of Managed Care
https://www.readbyqxmd.com/read/30448814/-characteristics-of-stress-resistance-and-adaptive-potential-in-the-training-of-doctors-in-the-system-of-postgraduate-education
#2
Svitlana P Koshova, Anatolii H Krut
OBJECTIVE: Introduction: The article deals with the peculiarities of physicians' stress in conditions of exam stress in postgraduate education as a structural-functional, dynamic, integrative property of the person, as a result of transactional process of collision of an individual with with the individual stress factors, which includes cognitive representation, the objective characterization of the situation and requirements for the individual. The course of diagnosis and adaptive capacity is considered in terms of physical, emotional and mental capacity, ability for social adaptation, to ensure the successful fulfillment, achievement of life goals, maintain homeostasis, efficiency and health...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/30431462/avoiding-physician-burnout-through-physical-emotional-and-spiritual-energy
#3
Sharon Karr
PURPOSE OF REVIEW: The purpose of this review is to update the physician community on current evidence regarding ways individuals can combat the rise in physician burnout. More than half of US physicians are experiencing at least some degree of burnout and the incidence has increased significantly over the past decade. RECENT FINDINGS: Recent findings suggest practicing physical, mental, and emotional self-care are important factors in avoiding physician burnout...
November 13, 2018: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/30430484/bibliometric-profile-of-tunisian-medical-publications-written-in-english-and-indexed-in-medline
#4
Imen Zemni, Mouna Safer, Imen Horrigue, Asma Ben Abdelaziz, Sonia Hammami, Ahmed Ben Abdelaziz
BACKGROUND: English is becoming nowadays the universal language of science. Rresearch published in English can be considered as a bibliometric indicator of the scientific productivity. AIM: We sought to describe the evolution of the Tunisian medical publications written in English over the period from 2004 to 2014. METHODS: Medline's database was consulted using a research query associating the names of the country and the main university cities both in French and in English...
July 2018: La Tunisie Médicale
https://www.readbyqxmd.com/read/30428338/-the-case-for-plerixafor-to-replace-filgrastim-as-the-optimal-agent-to-mobilize-peripheral-blood-donors-for-allogeneic-hematopoietic-cell-transplantation
#5
REVIEW
Stephen Couban, Peggy C Wong, Kirk R Schultz
G-CSF stimulated peripheral blood progenitor cells (G-PB) from either a related or unrelated donor continue to be the preferred donor source for most allogeneic hematopoietic cell transplantation (HCT). Recently, the ASBMT has recommended that marrow instead of G-PB as an unrelated graft source due to its lower rate of chronic graft-versus-host disease (cGVHD). The use of marrow is limited by both clinical considerations (slower rate of engraftment and increased donor morbidity) and logistic considerations (use of operating room resources and increased physician utilization), hence this recommendation has not been widely adopted...
November 11, 2018: Experimental Hematology
https://www.readbyqxmd.com/read/30427411/-we-live-on-the-tightrope-the-experience-of-health-professionals-working-with-hiv-aids-in-a-remote-area-of-northeast-brazil
#6
Thais Raquel Pires Tavares, Lucas Pereira de Melo
This ethnographic study aimed to understand the experience of health professionals working in a Specialized Service for HIV/AIDS Care in a remote area of Northeast Brazil. Data collection used participant observation and a semi-structured interview with seven professionals in the health care team. The thematic coding technique yielded three categories: "I didn't even know what it was": aspects of becoming a specialist in HIV/AIDS; "They're all out there, kind of hidden": strategies for dealing with the (in)visibility of serological status; and "We live on the tightrope": experiences in the work process...
November 8, 2018: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/30424758/primary-care-physicians-attitudes-to-the-adoption-of-electronic-medical-records-a-systematic-review-and-evidence-synthesis-using-the-clinical-adoption-framework
#7
Amy O'Donnell, Eileen Kaner, Caroline Shaw, Catherine Haighton
BACKGROUND: Recent decades have seen rapid growth in the implementation of Electronic Medical Records (EMRs) in healthcare settings in both developed regions as well as low and middle income countries. Yet despite substantial investment, the implementation of EMRs in some primary care systems has lagged behind other settings, with piecemeal adoption of EMR functionality by primary care physicians (PCPs) themselves. We aimed to review and synthesise international literature on the attitudes of PCPs to EMR adoption using the Clinical Adoption (CA) Framework...
November 13, 2018: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/30417941/the-generation-of-integration-the-early-experience-of-implementing-bundled-care-in-ontario-canada
#8
Gayathri Embuldeniya, Maritt Kirst, Kevin Walker, Walter P Wodchis
Policy Points: Policymakers interested in advancing integrated models of care may benefit from understanding how integration itself is generated. Integration is analyzed as the generation of connectivity and consensus-the coming together of people, practices, and things. Integration was mediated by chosen program structures and generated by establishing partnerships, building trust, developing thoughtful models, engaging clinicians in strategies, and sharing data across systems. This study provides examples of on-the-ground integration strategies in 6 programs, suggests contexts that better lend themselves to integration initiatives, and demonstrates how programs may be examined for the very thing they seek to implement-integration itself...
November 12, 2018: Milbank Quarterly
https://www.readbyqxmd.com/read/30415627/environmental-impact-reduction-as-a-new-dimension-for-quality-measurement-of-healthcare-services
#9
Amin Esmaeili, Charles McGuire, Michael Overcash, Kamran Ali, Seyed Soltani, Janet Twomey
PURPOSE: The purpose of this paper is to provide a detailed accounting of energy and materials consumed during magnetic resonance imaging (MRI). DESIGN/METHODOLOGY/APPROACH: The first and second stages of ISO standard (ISO 14040:2006 and ISO 14044:2006) were followed to develop life cycle inventory (LCI). The LCI data collection took the form of observations, time studies, real-time metered power consumption, review of imaging department scheduling records and review of technical manuals and literature...
October 8, 2018: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/30415591/identifying-intangible-assets-in-interprofessional-healthcare-organizations-feasibility-of-an-asset-inventory
#10
Elizabeth A Rider, Meg Comeau, Robert D Truog, Kayla Boyer, Elaine C Meyer
Healthcare systems increasingly use business models that focus on tangible assets such as finances and facilities. Yet intangible assets, such as values, relationships and human capital, remain critical for understanding the worth of interprofessional healthcare education and collaboration. We implemented a novel interprofessional collaborative pilot exercise to explore the feasibility and usefulness of an Asset Inventory-using KJ methodology and an appreciative inquiry perspective-to identify and better understand intangible assets and their value in interprofessional healthcare education/training organizations, for planning, and as a first step toward informing strategic decision-making...
November 11, 2018: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/30409338/screen-dr-collaborative-platform-for-diabetic-retinopathy
#11
Micael Pedrosa, Jorge Miguel Silva, João Figueira Silva, Sérgio Matos, Carlos Costa
BACKGROUND AND OBJECTIVE: Diabetic retinopathy (DR) is the most prevalent microvascular complication of diabetes mellitus and can lead to irreversible visual loss. Screening programs, based on retinal imaging techniques, are fundamental to detect the disease since the initial stages are asymptomatic. Most of these examinations reflect negative cases and many have poor image quality, representing an important inefficiency factor. The SCREEN-DR project aims to tackle this limitation, by researching and developing computer-aided methods for diabetic retinopathy detection...
December 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/30404773/health-care-professionals-social-media-behavior-and-the-underlying-factors-of-social-media-adoption-and-use-quantitative-study
#12
Joe Hazzam, Abdelmounaim Lahrech
BACKGROUND: In the last decade, social media has emerged as a newer platform for knowledge dissemination, information exchange, and interpersonal communication for health care professionals (HCPs). However, the underlying behaviors of HCPs and the ethical use of social media for productivity enhancement and a sustainable health care system remain ambiguous. OBJECTIVE: This study seeks to understand the factors that relate to the frequency use of social media in the health care discipline...
November 7, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/30401673/medical-correctness-and-user-friendliness-of-available-apps-for-cardiopulmonary-resuscitation-systematic-search-combined-with-guideline-adherence-and-usability-evaluation
#13
Bibiana Metelmann, Camilla Metelmann, Louisa Schuffert, Klaus Hahnenkamp, Peter Brinkrolf
BACKGROUND: In case of a cardiac arrest, start of cardiopulmonary resuscitation by a bystander before the arrival of the emergency personnel increases the probability of survival. However, the steps of high-quality resuscitation are not known by every bystander or might be forgotten in this complex and time-critical situation. Mobile phone apps offering real-time step-by-step instructions might be a valuable source of information. OBJECTIVE: The aim of this study was to examine mobile phone apps offering real-time instructions in German or English in case of a cardiac arrest, to evaluate their adherence to current resuscitation guidelines, and to test their usability...
November 6, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/30400919/personality-of-belgian-physicians-in-a-clinical-leadership-program
#14
Neree Claes, Hannelore Storms, Valérie Brabanders
BACKGROUND: Physician and non-physician leadership development programs aim to improve organizational performance. Although a significant, positive relation between physicians' leadership skills and patient outcomes, staff satisfaction and staff retention has been found, physicians are not formally trained in clinical leadership skills during their physician training. A lot of current healthcare leaders were chosen to take on leadership because of their productivity, published research, solid clinical skills, or because they were great educators, Heifetz RA...
November 6, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/30398990/reconfiguring-a-one-way-street-a-position-paper-on-why-and-how-to-improve-equity-in-global-physician-training
#15
James C Hudspeth, Tracy L Rabin, Bradley A Dreifuss, Mylo Schaaf, Michael S Lipnick, Christiana M Russ, Amy Meg Autry, Michael B Pitt, Virginia Rowthorn
Large numbers of U.S. physicians and medical trainees engage in hands-on clinical global health experiences abroad, where they gain skills working across cultures with limited resources. Increasingly, these experiences are becoming bidirectional, with providers from low- and middle-income countries traveling to experience health care in the United States, yet the same hands-on experiences afforded stateside physicians are rarely available for foreign medical graduates or postgraduate trainees when they arrive...
November 5, 2018: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/30398092/potential-dietary-supplement-and-medication-interactions-in-a-subset-of-the-older-adult-population-attending-congregate-sites
#16
Tracy V de Leon, Meizi He, Sarah L Ullevig
This study assessed possible dietary supplement-medication interactions of 62 older adults recruited from 8 senior congregate sites in Bexar County, Texas. Dietary supplement and medication use were collected by paper questionnaire and potential supplement-medication interactions were assessed using online databases. The majority of participants reported dietary supplements (77%), non-prescription medication (50%), and prescription medication (73%) use. Fifty percent of participants who reported dietary supplement and medication use were at-risk for a potential supplement-medication interaction, ranging from one to eight potential interactions...
November 6, 2018: Journal of Nutrition in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/30391545/the-first-3500-years-of-aspirin-history-from-its-roots-a-concise-summary
#17
REVIEW
Maria Rosa Montinari, Sergio Minelli, Raffaele De Caterina
Aspirin is currently the most widely used drug worldwide, and has been clearly one of the most important pharmacological achievements of the twentieth century. Historians of medicine have traced its birth in 1897, but the fascinating history of aspirin actually dates back >3500 years, when willow bark was used as a painkiller and antipyretic by Sumerians and Egyptians, and then by great physicians from ancient Greece and Rome. The modern history of aspirin precursors, salicylates, began in 1763 with Reverend Stone - who first described their antipyretic effects - and continued in the 19th century with many researchers involved in their extraction and chemical synthesis...
November 1, 2018: Vascular Pharmacology
https://www.readbyqxmd.com/read/30389582/gender-and-the-balance-of-parenting-and-professional-life-among-gynecology-subspecialists
#18
Emily K Hill, Ashley Stuckey, Stephen Fiascone, Christina Raker, Melissa A Clark, Amy Brown, Mary Gordinier, Katina Robison
STUDY OBJECTIVE: To compare the parenting and career patterns of female and male gynecology subspecialists. DESIGN: Cross-sectional survey study (Canadian Task Force Classification II-3) SETTING: Survey administered electronically (DataStat Illume) in February 2015 to physician members of the Society of Gynecologic Oncology (SGO), the American Society for Reproductive Medicine (ASRM), and the American Urogynecologic Society (AUGS). PATIENTS AND INTERVENTIONS: All physician members of the three national gynecology subspecialty organizations listed above...
October 30, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/30389284/bedside-ultrasonography-in-the-management-of-penetrating-cardiac-injury-caused-by-a-nail-gun
#19
Ashley T Panicker, Kenneth Nugent, Jennifer Mink, Jeffrey Glaser, Kevin Bradley, Franjo Siric, Jason T Nomura
BACKGROUND: Injuries from nail guns are a unique type of penetrating trauma seen in emergency departments (EDs), rising in prevalence in the United States. These devices can lead to life-threatening injuries that require rapid diagnosis to help guide management. CASE REPORT: An elderly man was brought to the ED having sustained a nail gun injury to the chest. After loss of pulses, brief closed chest compressions and rapid blood product administration led to a return of spontaneous circulation...
October 30, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/30388318/gender-and-age-significantly-determine-patient-needs-and-treatment-goals-in-psoriasis-a-lesson-for-practice
#20
J-T Maul, A A Navarini, R Sommer, F Anzengruber, C Sorbe, U Mrowietz, M Drach, C Blome, W-H Boehncke, D Thaci, K Reich, R von Kiedrowski, A Körber, N Yawalkar, C Mainetti, E Laffitte, M Streit, S Rustenbach, C Conrad, L Borradori, M Gilliet, A Cozzio, P Itin, P Häusermann, L E French, M A Radtke, M Augustin
BACKGROUND: Though patient needs are key drivers of treatment decisions, they are rarely systematically investigated in routine care. OBJECTIVE: This study aimed at analysing needs and expectations from the patient perspective in the German and Swiss psoriasis registries PsoBest and SDNTT with respect to treatment choice, age and gender. METHODS: The German and Swiss psoriasis registries observe patients recruited at first-time use of systemic drugs...
November 2, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
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