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dipak k mitra

Gulam Muhammed Al Kibria, Krystal Swasey, Allysha Choudhury, Vanessa Burrowes, Kristen A Stafford, S M Iftekhar Uddin, Mohammadhassan Mirbolouk, Atia Sharmeen, Angela Kc, Dipak K Mitra
We analyzed the Bangladesh Demographic and Health Survey 2011 data to examine absolute differences in hypertension prevalence according to the hypertension definition of the "2017 American College of Cardiology/American Heart Association (2017 ACC/AHA) Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults" and "Seventh Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC7)" 2003 guidelines. Among 7839 participants ≥35 years, the JNC7 and 2017 ACC/AHA classified 25...
June 13, 2018: Journal of Human Hypertension
Dipak K Mitra, Luke C Mullany, Meagan Harrison, Ishtiaq Mannan, Rashed Shah, Nazma Begum, Mamun Ibne Moin, Shams El Arifeen, Abdullah H Baqui
BACKGROUND: Infections cause about one fifth of the estimated 2.7 million annual neonatal deaths worldwide. Population-based data on burden and risk factors of neonatal infections are lacking in developing countries, which are required for the appropriate design of effective preventive and therapeutic interventions in resource-poor settings. METHODS: We used data from a community-based cluster-randomized trial conducted to evaluate the impact of two umbilical cord cleansing regimens with chlorhexidine solution on neonatal mortality and morbidity in a rural area of Sylhet District in Bangladesh...
March 9, 2018: Journal of Health, Population, and Nutrition
Fakir Md Yunus, Safayet Khan, Dipak K Mitra, Sabuj Kanti Mistry, Kaosar Afsana, Mahfuzar Rahman
OBJECTIVES: To investigate the association of total sleep time and presence or absence of snoring with chronic disease among the Bangladeshi adult population. DESIGN: Cross-sectional survey. SETTING: Urban and rural Bangladesh. PARTICIPANTS: A total of 12,338 men and women aged ≥35 years. MEASUREMENTS: Total sleep time was considered as the total hours of sleep in 24 hours. Furthermore, sleep time was categorized into <7, 7-9, and >9 hours according to National Sleep Foundation (2015) guidelines...
February 2018: Sleep Health
Rasheda Khanam, Andreea A Creanga, Alain K Koffi, Dipak K Mitra, Arif Mahmud, Nazma Begum, Syed Mamun Ibne Moin, Malathi Ram, Md Abdul Quaiyum, Saifuddin Ahmed, Samir K Saha, Abdullah H Baqui
BACKGROUND: The burden of maternal complications during antepartum and intrapartum periods is high and care seeking from a trained provider is low, particularly in low middle income countries of sub-Saharan Africa and South Asia. Identification of barriers to access to trained care and development of strategies to address them will contribute to improvements in maternal health. Using data from a community-based cohort of pregnant women, this study identified the prevalence of antepartum and intrapartum complications and determinants of care-seeking for these complications in rural Bangladesh...
2016: PloS One
Abdullah H Baqui, Dipak K Mitra, Nazma Begum, Lisa Hurt, Seyi Soremekun, Karen Edmond, Betty Kirkwood, Nita Bhandari, Sunita Taneja, Sarmila Mazumder, Muhammad Imran Nisar, Fyezah Jehan, Muhammad Ilyas, Murtaza Ali, Imran Ahmed, Shabina Ariff, Sajid B Soofi, Sunil Sazawal, Usha Dhingra, Arup Dutta, Said M Ali, Shaali M Ame, Katherine Semrau, Fern M Hamomba, Caroline Grogan, Davidson H Hamer, Rajiv Bahl, Sachiyo Yoshida, Alexander Manu
OBJECTIVE: To estimate neonatal mortality, particularly within 24 hours of birth, in six low- and lower-middle-income countries. METHODS: We analysed epidemiological data on a total of 149 570 live births collected between 2007 and 2013 in six prospective randomized trials and a cohort study from predominantly rural areas of Bangladesh, Ghana, India, Pakistan, the United Republic of Tanzania and Zambia. The neonatal mortality rate and mortality within 24 hours of birth were estimated for all countries and mortality within 6 hours was estimated for four countries with available data...
October 1, 2016: Bulletin of the World Health Organization
Anne Cc Lee, Luke C Mullany, Karima Ladhani, Jamal Uddin, Dipak Mitra, Parvez Ahmed, Parul Christian, Alain Labrique, Sushil K DasGupta, R Peter Lokken, Mohammed Quaiyum, Abdullah H Baqui
BACKGROUND: Gestational age (GA) is frequently unknown or inaccurate in pregnancies in low-income countries. Early identification of preterm infants may help link them to potentially life-saving interventions. METHODS: We conducted a validation study in a community-based birth cohort in rural Bangladesh. GA was determined by pregnancy ultrasound (<20 weeks). Community health workers conducted home visits (<72 hours) to assess physical/neuromuscular signs and measure anthropometrics...
July 2016: Pediatrics
Mohammad Shahidul Islam, Abdullah H Baqui, Anita K Zaidi, Zulfiqar A Bhutta, Pinaki Panigrahi, Anuradha Bose, Sajid B Soofi, Abdul Momin Kazi, Dipak K Mitra, Rita Isaac, Pritish Nanda, Nicholas E Connor, Daniel E Roth, Shamim A Qazi, Shams El Arifeen, Samir K Saha
BACKGROUND: Insufficient knowledge of the etiology and risk factors for community-acquired neonatal infection in low-income countries is a barrier to designing appropriate intervention strategies for these settings to reduce the burden and treatment of young infant infection. To address these gaps, we are conducting the Aetiology of Neonatal Infection in South Asia (ANISA) study among young infants in Bangladesh, India and Pakistan. The objectives of ANISA are to establish a comprehensive surveillance system for registering newborns in study catchment areas and collecting data on bacterial and viral etiology and associated risk factors for infections among young infants aged 0-59 days...
May 2016: Pediatric Infectious Disease Journal
Dipak K Mitra, Arif Mahmud, Nazma Begum, Iftekhar Rafiqullah, Arunangshu Roy, Syed Mamun Ibne Moin, Maksuda Islam, Md Abdul Quaiyum, Jannatul Ferdous, Jennifer A Applegate, Samir K Saha, Abdullah H Baqui
BACKGROUND: Despite the high rate of deaths in young infants (0-59 days) attributable to infections in resource-poor countries, data on bacterial and viral etiologies of community-acquired infections in this age group are limited. These data are needed to develop appropriate preventive strategies and suitable antibiotic treatment regimens for reducing the number of young infant deaths from infections. The Aetiology of Neonatal Infection in South Asia (ANISA) study is designed to generate these critical data and is being implemented in Bangladesh, India and Pakistan...
May 2016: Pediatric Infectious Disease Journal
Rakesh K Arya, Akhilesh Singh, Navneet K Yadav, Srikanth H Cheruvu, Zakir Hossain, Sanjeev Meena, Shrankhla Maheshwari, Anup K Singh, Uzma Shahab, Chetan Sharma, Kavita Singh, Tadigoppula Narender, Kalyan Mitra, Kamal R Arya, Rama K Singh, Jiaur R Gayen, Dipak Datta
Major challenges for current therapeutic strategies against breast cancer are associated with drug-induced toxicities. Considering the immense potential of bioactive phytochemicals to deliver non-toxic, efficient anti-cancer therapeutics, we performed bio-guided fractionation of Eclipta alba extract and discovered that particularly the chloroform fraction of Eclipta alba (CFEA) is selectively inducing cytotoxicity to breast cancer cells over non-tumorigenic breast epithelial cells. Our unbiased mechanistic hunt revealed that CFEA specifically activates the intrinsic apoptotic pathway by disrupting the mitochondrial membrane potential, upregulating Hsp60 and downregulating the expression of anti-apoptotic protein XIAP...
December 17, 2015: Scientific Reports
Anne C C Lee, Mohammad A Quaiyum, Luke C Mullany, Dipak K Mitra, Alain Labrique, Parvez Ahmed, Jamal Uddin, Iftekhar Rafiqullah, Sushil DasGupta, Arif Mahmud, Emilia H Koumans, Parul Christian, Samir Saha, Abdullah H Baqui
BACKGROUND: Approximately half of preterm births are attributable to maternal infections, which are commonly undetected and untreated in low-income settings. Our primary aim is to determine the impact of early pregnancy screening and treatment of maternal genitourinary tract infections on the incidence of preterm live birth in Sylhet, Bangladesh. We will also assess the effect on other adverse pregnancy outcomes, including preterm birth (stillbirth and live birth), late miscarriage, maternal morbidity, and early onset neonatal sepsis...
December 7, 2015: BMC Pregnancy and Childbirth
Abdullah H Baqui, Samir K Saha, A S M Nawshad Uddin Ahmed, Mohammad Shahidullah, Iftekhar Quasem, Daniel E Roth, A K M Samsuzzaman, Wazir Ahmed, S M Shahnawaz Bin Tabib, Dipak K Mitra, Nazma Begum, Maksuda Islam, Arif Mahmud, Mohammad Hefzur Rahman, Mamun Ibne Moin, Luke C Mullany, Simon Cousens, Shams El Arifeen, Stephen Wall, Neal Brandes, Mathuram Santosham, Robert E Black
BACKGROUND: Severe infections remain one of the main causes of neonatal deaths worldwide. Possible severe infection is diagnosed in young infants (aged 0-59 days) according to the presence of one or more clinical signs. The recommended treatment is hospital admission with 7-10 days of injectable antibiotic therapy. In low-income and middle-income countries, barriers to hospital care lead to delayed, inadequate, or no treatment for many young infants. We aimed to identify effective alternative antibiotic regimens to expand treatment options for situations where hospital admission is not possible...
May 2015: Lancet Global Health
Abdullah H Baqui, Samir Kumar Saha, A S M Nawshad Uddin Ahmed, Mohammad Shahidullah, Iftekhar Quasem, Daniel E Roth, Emma K Williams, Dipak Mitra, A K M Shamsuzzaman, Wazir Ahmed, Luke C Mullany, Simon Cousens, Stephen Wall, Neal Brandes, Robert E Black
BACKGROUND: Because access to care is limited in settings with high mortality, exclusive reliance on the current recommendation of 7-10 days of parenteral antibiotic treatment is a barrier to provision of adequate treatment of newborn infections. METHODS: We are conducting a trial to determine if simplified antibiotic regimens with fewer injections are as efficacious as the standard course of parenteral antibiotics for empiric treatment of young infants with clinical signs suggestive of severe infection in 4 urban hospitals and in a rural surveillance site in Bangladesh...
September 2013: Pediatric Infectious Disease Journal
Veena Kumari, Nilay Biswas, Nilanjan Mitra, Hiralal Konar, Dipak Ghosh, Sukanta K Das
AIM: Traditionally, ligation of hernial sac during orchiopexy is considered mandatory to prevent postoperative development of hernia. A prospective study was carried out to see if it is actually required based on the fact that any peritoneal defect closes within 24 hours by metamorphosis of the in situ mesodermal cells. METHODS: Fifty cases of undescended testis, age ranging from eight months to 12 years were enrolled. All of them underwent standard orchiopexy without ligation of the hernial sac...
April 2009: Journal of Indian Association of Pediatric Surgeons
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