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https://www.readbyqxmd.com/read/28430753/impact-of-chlorhexidine-cord-cleansing-on-mortality-omphalitis-and-cord-separation-time-among-facility-born-babies-in-nepal-and-bangladesh
#1
Luke C Mullany, Shams El Arifeen, Subarna K Khatry, Joanne Katz, Rashed Shah, Abdullah H Baqui, James M Tielsch
Guidance is needed regarding potential extension of the WHO recommendation for cord cleansing with chlorhexidine to babies born in facilities. Among 3,223 facility-born babies from Nepal and Bangladesh, mortality was approximately halved among those allocated to the intervention clusters (10.5/1000 vs. 19.4/1000, RR=0.54; 95% CI: 0.30 - 0.97). In high-mortality settings, a single policy for home and facility births is warranted.
April 19, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28334973/analysis-of-dropout-across-the-continuum-of-maternal-health-care-in-tanzania-findings-from-a-cross-sectional-household-survey
#2
Diwakar Mohan, Amnesty E LeFevre, Asha George, Rose Mpembeni, Eva Bazant, Neema Rusibamayila, Japhet Killewo, Peter J Winch, Abdullah H Baqui
The 'continuum of care' is proposed as a key framework for the delivery of maternal, neonatal and child health services. This study examined the extent of dropout as well as factors associated with retention across the MNCH continuum from antenatal care (ANC), through skilled birth attendance (SBA), to postnatal care (PNC).We analyzed data from 1931 women who delivered in the preceding 2-14 months, from a two-stage cluster sampling household survey in four districts of Tanzania's Morogoro region. The survey was conducted in 2011 as a part of a baseline for an independent evaluation of a maternal health program...
March 16, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28270117/antepartum-complications-and-perinatal-mortality-in-rural-bangladesh
#3
Rasheda Khanam, Saifuddin Ahmed, Andreea A Creanga, Nazma Begum, Alain K Koffi, Arif Mahmud, Heather Rosen, Abdullah H Baqui
BACKGROUND: Despite impressive improvements in maternal survival throughout the world, rates of antepartum complications remain high. These conditions also contribute to high rates of perinatal deaths, which include stillbirths and early neonatal deaths, but the extent is not well studied. This study examines patterns of antepartum complications and the risk of perinatal deaths associated with such complications in rural Bangladesh. METHODS: We used data on self-reported antepartum complications during the last pregnancy and corresponding pregnancy outcomes from a household survey (N = 6,285 women) conducted in Sylhet district, Bangladesh in 2006...
March 7, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28132873/detection-of-macrolide-resistance-genes-in-culture-negative-specimens-from-bangladeshi-children-with-invasive-pneumococcal-diseases
#4
Md Hasanuzzaman, Roly Malaker, Maksuda Islam, Abdullah H Baqui, Gary L Darmstadt, Cynthia G Whitney, Samir K Saha
OBJECTIVES: In recent years, an increasing prevalence of macrolide resistance among pneumococci in Bangladesh has been observed. However, the scenario remains incomplete, as few isolates (<1%) are available from pneumonia cases and most pneumococcal meningitis cases (>80%) are culture-negative. This study optimised a triplex PCR method to detect macrolide resistance genes (MRGs) (mefA and ermB) and cpsA from culture-negative pneumococcal cases to predict the prevalence and level of macrolide resistance...
January 26, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/27997537/patterns-and-determinants-of-care-seeking-for-antepartum-and-intrapartum-complications-in-rural-bangladesh-results-from-a-cohort-study
#5
Rasheda Khanam, Andreea A Creanga, Alain K Koffi, Dipak K Mitra, Arif Mahmud, Nazma Begum, Syed Mamun Ibne Moin, Malathi Ram, Md Abdul Quaiyum, Saifuddin Ahmed, Samir K Saha, Abdullah H Baqui
BACKGROUND: The burden of maternal complications during antepartum and intrapartum periods is high and care seeking from a trained provider is low, particularly in low middle income countries of sub-Saharan Africa and South Asia. Identification of barriers to access to trained care and development of strategies to address them will contribute to improvements in maternal health. Using data from a community-based cohort of pregnant women, this study identified the prevalence of antepartum and intrapartum complications and determinants of care-seeking for these complications in rural Bangladesh...
2016: PloS One
https://www.readbyqxmd.com/read/27843165/neonatal-mortality-within-24%C3%A2-hours-of-birth-in-six-low-and-lower-middle-income-countries
#6
Abdullah H Baqui, Dipak K Mitra, Nazma Begum, Lisa Hurt, Seyi Soremekun, Karen Edmond, Betty Kirkwood, Nita Bhandari, Sunita Taneja, Sarmila Mazumder, Muhammad Imran Nisar, Fyezah Jehan, Muhammad Ilyas, Murtaza Ali, Imran Ahmed, Shabina Ariff, Sajid B Soofi, Sunil Sazawal, Usha Dhingra, Arup Dutta, Said M Ali, Shaali M Ame, Katherine Semrau, Fern M Hamomba, Caroline Grogan, Davidson H Hamer, Rajiv Bahl, Sachiyo Yoshida, Alexander Manu
OBJECTIVE: To estimate neonatal mortality, particularly within 24 hours of birth, in six low- and lower-middle-income countries. METHODS: We analysed epidemiological data on a total of 149 570 live births collected between 2007 and 2013 in six prospective randomized trials and a cohort study from predominantly rural areas of Bangladesh, Ghana, India, Pakistan, the United Republic of Tanzania and Zambia. The neonatal mortality rate and mortality within 24 hours of birth were estimated for all countries and mortality within 6 hours was estimated for four countries with available data...
October 1, 2016: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/27843130/reduction-of-childhood-pneumonia-mortality-in-the-sustainable-development-era
#7
Eric D McCollum, Carina King, Laura L Hammitt, Amy S Ginsburg, Tim Colbourn, Abdullah H Baqui, Katherine L O'Brien
No abstract text is available yet for this article.
December 2016: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/27455441/prevalence-serotype-distribution-and-mortality-risk-associated-with-group-b-streptococcus-colonization-of-newborns-in-rural-bangladesh
#8
Mohammad Shahidul Islam, Samir K Saha, Maksuda Islam, Joyanta K Modak, Rashed Shah, Radwanur R Talukder, Shams El Arifeen, Abdullah H Baqui, Gary L Darmstadt, Luke C Mullany
BACKGROUND: Group B Streptococcus (GBS) is a predominant cause of early-onset neonatal sepsis (EOS) globally; however, the impact of this organism on the health of newborns in South Asia is debated, due in part to a paucity of community-based assessments. We estimated the prevalence and serotypes of GBS colonization of the umbilical cord stump, and the association of colonization with mortality in a population-based cohort of newborns in rural Sylhet District, Bangladesh. METHODS: Umbilical cord swabs were collected from 646 newborns up to three times within the first week after birth (ages <24 hours, ~3 days, ~6 days) and processed to identify GBS serotypes...
July 22, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27350876/factors-associated-with-delay-in-care-seeking-for-fatal-neonatal-illness-in-the-sylhet-district-of-bangladesh-results-from-a-verbal-and-social-autopsy-study
#9
Bareng As Nonyane, Narjis Kazmi, Alain K Koffi, Nazma Begum, Salahuddin Ahmed, Abdullah H Baqui, Henry D Kalter
BACKGROUND: We conducted a social and verbal autopsy study to determine cultural-, social- and health system-related factors that were associated with the delay in formal care seeking in Sylhet district, Bangladesh. METHODS: Verbal and social autopsy interviews were conducted with mothers who experienced a neonatal death between October 2007 and May 2011. We fitted a semi-parametric regression model of the cumulative incidence of seeking formal care first, accounting for competing events of death or seeking informal care first...
June 2016: Journal of Global Health
https://www.readbyqxmd.com/read/27313070/validity-of-newborn-clinical-assessment-to-determine-gestational-age-in-bangladesh
#10
Anne Cc Lee, Luke C Mullany, Karima Ladhani, Jamal Uddin, Dipak Mitra, Parvez Ahmed, Parul Christian, Alain Labrique, Sushil K DasGupta, R Peter Lokken, Mohammed Quaiyum, Abdullah H Baqui
BACKGROUND: Gestational age (GA) is frequently unknown or inaccurate in pregnancies in low-income countries. Early identification of preterm infants may help link them to potentially life-saving interventions. METHODS: We conducted a validation study in a community-based birth cohort in rural Bangladesh. GA was determined by pregnancy ultrasound (<20 weeks). Community health workers conducted home visits (<72 hours) to assess physical/neuromuscular signs and measure anthropometrics...
July 2016: Pediatrics
https://www.readbyqxmd.com/read/27117481/a-qualitative-exploration-of-health-workers-and-clients-perceptions-of-barriers-to-completing-four-antenatal-care-visits-in-morogoro-region-tanzania
#11
Jennifer A Callaghan-Koru, Shannon A McMahon, Joy J Chebet, Charles Kilewo, Gasto Frumence, Shivam Gupta, Raz Stevenson, Chrisostom Lipingu, Abdullah H Baqui, Peter J Winch
Antenatal care (ANC) remains an important contact point on the continuum of care for mothers and children in low- and middle-income countries. In Tanzania, the proportion of pregnant women completing at least four ANC visits (ANC-4) dropped from 70% to 43% between 1999 and 2010. To identify potential causes of the decline in the number of ANC visits, we conducted qualitative research at 18 health centres in Morogoro Region, exploring providers' communication about ANC visits and clients' and providers' perceptions of changes in ANC services and barriers to completing four visits...
October 2016: Health Policy and Planning
https://www.readbyqxmd.com/read/27096958/rotavirus-surveillance-at-a-who-coordinated-invasive-bacterial-disease-surveillance-site-in-bangladesh-a-feasibility-study-to-integrate-two-surveillance-systems
#12
Arif Mohammad Tanmoy, Asm Nawshad Uddin Ahmed, Rajesh Arumugam, Belal Hossain, Mahfuza Marzan, Shampa Saha, Shams El Arifeen, Abdullah H Baqui, Robert E Black, Gagandeep Kang, Samir Kumar Saha
The World Health Organization (WHO) currently coordinates rotavirus diarrhea and invasive bacterial disease (IBD) surveillance at 178 sentinel sites in 60 countries. However, only 78 sites participate in both surveillance systems using a common sentinel site. Here, we explored the feasibility of extending a WHO-IBD surveillance platform to generate data on the burden of rotaviral diarrhea and its epidemiological characteristics to prepare the countries to measure the impact of rotaviral vaccine. A six-month (July to December, 2012) surveillance, managed by IBD team, collected stool samples and clinical data from under-five children with acute watery diarrhea at an IBD sentinel site...
2016: PloS One
https://www.readbyqxmd.com/read/27070072/infection-surveillance-protocol-for-a-multicountry-population-based-study-in-south-asia-to-determine-the-incidence-etiology-and-risk-factors-for-infections-among-young-infants-of-0-to-59-days-old
#13
Mohammad Shahidul Islam, Abdullah H Baqui, Anita K Zaidi, Zulfiqar A Bhutta, Pinaki Panigrahi, Anuradha Bose, Sajid B Soofi, Abdul Momin Kazi, Dipak K Mitra, Rita Isaac, Pritish Nanda, Nicholas E Connor, Daniel E Roth, Shamim A Qazi, Shams El Arifeen, Samir K Saha
BACKGROUND: Insufficient knowledge of the etiology and risk factors for community-acquired neonatal infection in low-income countries is a barrier to designing appropriate intervention strategies for these settings to reduce the burden and treatment of young infant infection. To address these gaps, we are conducting the Aetiology of Neonatal Infection in South Asia (ANISA) study among young infants in Bangladesh, India and Pakistan. The objectives of ANISA are to establish a comprehensive surveillance system for registering newborns in study catchment areas and collecting data on bacterial and viral etiology and associated risk factors for infections among young infants aged 0-59 days...
May 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27070066/implementation-of-the-anisa-protocol-in-sylhet-bangladesh-challenges-and-solutions
#14
Dipak K Mitra, Arif Mahmud, Nazma Begum, Iftekhar Rafiqullah, Arunangshu Roy, Syed Mamun Ibne Moin, Maksuda Islam, Md Abdul Quaiyum, Jannatul Ferdous, Jennifer A Applegate, Samir K Saha, Abdullah H Baqui
BACKGROUND: Despite the high rate of deaths in young infants (0-59 days) attributable to infections in resource-poor countries, data on bacterial and viral etiologies of community-acquired infections in this age group are limited. These data are needed to develop appropriate preventive strategies and suitable antibiotic treatment regimens for reducing the number of young infant deaths from infections. The Aetiology of Neonatal Infection in South Asia (ANISA) study is designed to generate these critical data and is being implemented in Bangladesh, India and Pakistan...
May 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27070065/classification-of-blood-culture-isolates-into-contaminants-and-pathogens-on-the-basis-of-clinical-and-laboratory-data
#15
Belal Hossain, Martin W Weber, Davidson H Hamer, Patricia L Hibberd, A S M Nawshad Uddin Ahmed, Mahfuza Marzan, Maksuda Islam, Nicholas E Connor, Mohammad Shahidul Islam, Anita K Zaidi, Abdullah H Baqui, Zulfiqar A Bhutta, Shahida M Qureshi, Iftekhar Rafiqullah, Lesley McGee, Samir K Saha
The multisite community-based study, Aetiology of Neonatal Infection in South Asia (ANISA), uses blood culture as the gold standard for identifying the etiology of neonatal infection. Considering the importance of this age-old diagnostic tool and the risk of contamination, ANISA has employed rigorous measures to prevent contamination at all stages of blood collection, processing and culture. Because contamination may still occur, an independent expert group evaluates the routinely collected clinical and laboratory data to determine whether a blood culture isolate is a contaminant or a true pathogen...
May 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27070063/methods-employed-in-monitoring-and-evaluating-field-and-laboratory-systems-in-the-anisa-study-ensuring-quality
#16
Nicholas E Connor, Mohammad Shahidul Islam, Melissa L Arvay, Abdullah H Baqui, Anita K Zaidi, Sajid B Soofi, Pinaki Panigrahi, Anuradha Bose, Maksuda Islam, Shams El Arifeen, Samir K Saha, Shamim A Qazi
BACKGROUND: The Aetiology of Neonatal Infection in South Asia (ANISA) study maintains operations in Bangladesh, India and Pakistan. We developed and deployed a multilayered monitoring system to measure performance indicators of field sites and laboratory operations. This system allows for real-time provision of feedback to study site teams and project stakeholders. The goal of this monitoring and evaluation system is to promote optimal performance and consistency in protocol application at all sites over the course of the study, thereby safeguarding the validity of project findings...
May 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/26825324/journal-of-health-population-and-nutrition-celebrating-an-exciting-new-phase
#17
EDITORIAL
Abdullah H Baqui
No abstract text is available yet for this article.
August 13, 2015: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/26784272/effect-of-weekly-high-dose-vitamin-d3-supplementation-on-serum-cholecalciferol-concentrations-in-pregnant-women
#18
RANDOMIZED CONTROLLED TRIAL
Michelle C Dimitris, Nandita Perumal, Hayley A Craig-Barnes, Michael Leadley, Abdullah A Mahmud, Abdullah H Baqui, Daniel E Roth
Vitamin D status is conventionally defined by the serum concentration of 25-hydroxyvitamin D. However, it has been proposed that the serum cholecalciferol concentration (D3) also determines functional vitamin D sufficiency. The objective of this study was to describe the effect of weekly high-dose vitamin D3 supplementation on inter-dose serum D3 in pregnant women. We conducted a sub-study of a completed randomized double-blind placebo-controlled trial of vitamin D3 (35,000 IU/week) supplementation in late pregnancy (AViDD trial) in Dhaka, Bangladesh...
April 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/26703439/profile-knowledge-and-work-patterns-of-a-cadre-of-maternal-newborn-and-child-health-chws-focusing-on-preventive-and-promotive-services-in-morogoro-region-tanzania
#19
MULTICENTER STUDY
Amnesty E LeFevre, Rose Mpembeni, Dereck Chitama, Asha S George, Diwakar Mohan, David P Urassa, Shivam Gupta, Isabelle Feldhaus, Audrey Pereira, Charles Kilewo, Joy J Chebet, Chelsea M Cooper, Giulia Besana, Harriet Lutale, Dunstan Bishanga, Emmanuel Mtete, Helen Semu, Abdullah H Baqui, Japhet Killewo, Peter J Winch
BACKGROUND: Despite impressive decreases in under-five mortality, progress in reducing maternal and neonatal mortality in Tanzania has been slow. We present an evaluation of a cadre of maternal, newborn, and child health community health worker (MNCH CHW) focused on preventive and promotive services during the antenatal and postpartum periods in Morogoro Region, Tanzania. Study findings review the effect of several critical design elements on knowledge, time allocation, service delivery, satisfaction, and motivation...
2015: Human Resources for Health
https://www.readbyqxmd.com/read/26658530/epidemiology-of-invasive-pneumococcal-disease-in-bangladeshi-children-before-introduction-of-pneumococcal-conjugate-vaccine
#20
Samir K Saha, Belal Hossain, Maksuda Islam, Md Hasanuzzaman, Shampa Saha, Mohammad Hasan, Gary L Darmstadt, Mrittika Chowdury, Shams El Arifeen, Abdullah H Baqui, Robert F Breiman, Mathuram Santosham, Stephen P Luby, Cynthia G Whitney
BACKGROUND: Because Bangladesh intended to introduce pneumococcal conjugate vaccine (PCV)-10 in 2015, we examined the baseline burden of invasive pneumococcal disease (IPD) to measure impact of PCV. METHODS: During 2007-2013, we performed blood and cerebrospinal fluid cultures in children <5 years old with suspected IPD identified through active surveillance at 4 hospitals. Isolates were serotyped by quellung and tested for antibiotic susceptibility by disc diffusion and E-test...
June 2016: Pediatric Infectious Disease Journal
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