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JOURNAL ARTICLE
Anne Cc Lee, Sara Cherkerzian, Fahmida Tofail, Lian V Folger, Salahuddin Ahmed, Sayedur Rahman, Nabid H Chowdhury, Rasheda Khanam, Ingrid Olson, Emily Oken, Raina Fichorova, Charles A Nelson, Abdullah H Baqui, Terrie Inder
BACKGROUND: There are limited data on the impact of perinatal inflammation on child neurodevelopment in low-middle income countries and among growth-restricted infants. METHODS: Population-based, prospective birth cohort study of 288 infants from July 2016-March 2017 in Sylhet, Bangladesh. Umbilical cord blood was analyzed for interleukin(IL)-1α, IL-1β, IL-6, IL-8, and C-reactive protein(CRP). Child neurodevelopment was assessed at 24 months with Bayley-III Scales of Infant Development...
April 8, 2024: Pediatric Research
#2
JOURNAL ARTICLE
Jennifer A Applegate, Md Shafiqul Islam, Rasheda Khanam, Arunangshu Dutta Roy, Nabidul Haque Chowdhury, Salahuddin Ahmed, Dipak K Mitra, Arif Mahmud, Mohammad Shahidul Islam, Samir K Saha, Abdullah H Baqui
OBJECTIVE: To assess the relative risk of mortality in preterm and small-for-gestational-age (SGA) infants during the first and second months of life in rural Bangladesh. STUDY DESIGN: We analyzed data from a cohort of pregnant women and their babies in Sylhet, Bangladesh, assembled between 2011 and 2014. Community health workers visited enrolled babies up to 10 times from birth to age 59 days. Survival status was recorded at each visit. Gestational age was estimated from mother's reported last menstrual period...
March 1, 2024: Journal of Pediatrics
#3
JOURNAL ARTICLE
Elizabeth A Hazel, Daniel J Erchick, Joanne Katz, Anne C C Lee, Michael Diaz, Lee S F Wu, Keith P West, Abu Ahmed Shamim, Parul Christian, Hasmot Ali, Abdullah H Baqui, Samir K Saha, Salahuddin Ahmed, Arunangshu Dutta Roy, Mariângela F Silveira, Romina Buffarini, Roger Shapiro, Rebecca Zash, Patrick Kolsteren, Carl Lachat, Lieven Huybregts, Dominique Roberfroid, Zhonghai Zhu, Lingxia Zeng, Seifu H Gebreyesus, Kokeb Tesfamariam, Seth Adu-Afarwuah, Kathryn G Dewey, Stephaney Gyaase, Kwaku Poku-Asante, Ellen Boamah Kaali, Darby Jack, Thulasiraj Ravilla, James Tielsch, Sunita Taneja, Ranadip Chowdhury, Per Ashorn, Kenneth Maleta, Ulla Ashorn, Charles Mangani, Luke C Mullany, Subarna K Khatry, Vundli Ramokolo, Wanga Zembe-Mkabile, Wafaie W Fawzi, Dongqing Wang, Christentze Schmiegelow, Daniel Minja, Omari Abdul Msemo, John P A Lusingu, Emily R Smith, Honorati Masanja, Aroonsri Mongkolchati, Paniya Keentupthai, Abel Kakuru, Richard Kajubi, Katherine Semrau, Davidson H Hamer, Albert Manasyan, Jake M Pry, Bernard Chasekwa, Jean Humphrey, Robert E Black
OBJECTIVE: To describe the mortality risks by fine strata of gestational age and birthweight among 230 679 live births in nine low- and middle-income countries (LMICs) from 2000 to 2017. DESIGN: Descriptive multi-country secondary data analysis. SETTING: Nine LMICs in sub-Saharan Africa, Southern and Eastern Asia, and Latin America. POPULATION: Liveborn infants from 15 population-based cohorts. METHODS: Subnational, population-based studies with high-quality birth outcome data were invited to join the Vulnerable Newborn Measurement Collaboration...
January 16, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
#4
JOURNAL ARTICLE
Muhammad Imran Nisar, Sayan das, Rasheda Khanam, Javairia Khalid, Swagata Chetia, Tarik Hasan, Shahira Shahid, Msafiri Ladislaus Marijani, Salahuddin Ahmed, Farah Khalid, Said Mohammed Ali, Nabidul Haque Chowdhury, Usma Mehmood, Arup Dutta, Sayedur Rahman, Muhammad Farrukh Qazi, Saikat Deb, Dipak Kumar Mitra, Asra Abeer Usmani, Usha Dhingra, Rubhana Raqib, Alexander Manu, Sachiyo Yoshida, Nicole Minckas, Rajiv Bahl, Abdullah H Baqui, Sunil Sazawal, Fyezah Jehan
BACKGROUND: Hyperglycemia during pregnancy leads to adverse maternal and fetal outcomes. Thus, strict monitoring of blood glucose levels is warranted. This study aims to determine the association of early to mid-pregnancy HbA1c levels with the development of pregnancy complications in women from three countries in South Asia and Sub-Saharan Africa. METHODS: We performed a secondary analysis of the AMANHI (Alliance for Maternal and Newborn Health Improvement) cohort, which enrolled 10,001 pregnant women between May 2014 and June 2018 across Sylhet-Bangladesh, Karachi-Pakistan, and Pemba Island-Tanzania...
January 15, 2024: BMC Pregnancy and Childbirth
#5
RANDOMIZED CONTROLLED TRIAL
Eleanor Wilson, Jaya Goswami, Abdullah H Baqui, Pablo A Doreski, Gonzalo Perez-Marc, Khalequ Zaman, Jorge Monroy, Christopher J A Duncan, Mugen Ujiie, Mika Rämet, Lina Pérez-Breva, Ann R Falsey, Edward E Walsh, Rakesh Dhar, Lauren Wilson, Jiejun Du, Parinaz Ghaswalla, Archana Kapoor, Lan Lan, Shraddha Mehta, Runa Mithani, Catherine A Panozzo, Alana K Simorellis, Barbara J Kuter, Florian Schödel, Wenmei Huang, Caroline Reuter, Karen Slobod, Sonia K Stoszek, Christine A Shaw, Jacqueline M Miller, Rituparna Das, Grace L Chen
BACKGROUND: Respiratory syncytial virus (RSV) can cause substantial morbidity and mortality among older adults. An mRNA-based RSV vaccine, mRNA-1345, encoding the stabilized RSV prefusion F glycoprotein, is under clinical investigation. METHODS: In this ongoing, randomized, double-blind, placebo-controlled, phase 2-3 trial, we randomly assigned, in a 1:1 ratio, adults 60 years of age or older to receive one dose of mRNA-1345 (50 μg) or placebo. The two primary efficacy end points were the prevention of RSV-associated lower respiratory tract disease with at least two signs or symptoms and with at least three signs or symptoms...
December 14, 2023: New England Journal of Medicine
#6
JOURNAL ARTICLE
Roly Malaker, Md Hasanuzzaman, Yogesh Hooda, Hafizur Rahman, Rajib Chandra Das, Naito Kanon, Senjuti Saha, Arif M Tanmoy, Sowmitra Ranjan Chakraborty, Shampa Saha, Maksuda Islam, Gary L Darmstadt, Abdullah H Baqui, Mathuram Sathosam, Shams El-Arifeen, Cynthia G Whitney, Samir K Saha
The 10-valent pneumococcal conjugate vaccine (PCV10) was introduced in March 2015 in Bangladesh. In this study, we aimed to estimate the impact of PCV10 on invasive pneumococcal disease (IPD) identified by blood cultures and severe pneumonia identified clinically and its effectiveness on invasive disease caused by vaccine serotypes. We conducted population-based surveillance among children aged 2- <24 months between April 2012 through March 2019 in Mirzapur, a rural sub-district of Bangladesh. We compared incidence of IPD and severe pneumonia before (April 2012 to March 2015) and after (April 2015 to March 2019) the introduction of PCV10...
December 8, 2023: Vaccine
#7
JOURNAL ARTICLE
Nagendra K Monangi, Huan Xu, Yuemei Fan, Rasheeda Khanam, Waqasuddin Khan, Saikat Deb, Jesmin Pervin, Joan T Price, Lovejeet Kaur, Abdullah Al Mahmud, Le Quang Thanh, Angharad Care, Julio A Landero, Gerald F Combs, Elizabeth Belling, Joanne Chappell, Jing Chen, Fansheng Kong, Craig Lacher, Salahuddin Ahmed, Nabidul Haque Chowdhury, Sayedur Rahman, Furqan Kabir, Imran Nisar, Aneeta Hotwani, Usma Mehmood, Ambreen Nizar, Javairia Khalid, Usha Dhingra, Arup Dutta, Said Mohamed Ali, Fahad Aftab, Mohammed Hamad Juma, Monjur Rahman, Tahmeed Ahmed, M Munirul Islam, Bellington Vwalika, Patrick Musonda, Ulla Ashorn, Kenneth Maleta, Mikko Hallman, Laura Goodfellow, Juhi K Gupta, Ana Alfirevic, Susan K Murphy, Larry Rand, Kelli K Ryckman, Jeffrey C Murray, Rajiv Bahl, James A Litch, Courtney Baruch-Gravett, Shailaja Sopory, Uma Chandra Mouli Natchu, Pavitra V Kumar, Neha Kumari, Ramachandran Thiruvengadam, Atul Kumar Singh, Pankaj Kumar, Zarko Alfirevic, Abdullah H Baqui, Shinjini Bhatnagar, Jane E Hirst, Cathrine Hoyo, Fyezah Jehan, Laura Jelliffe-Pawlowski, Anisur Rahman, Daniel E Roth, Sunil Sazawal, Jeffrey S A Stringer, Per Ashorn, Ge Zhang, Louis J Muglia
BACKGROUND: Copper (Cu), an essential trace mineral regulating multiple actions of inflammation and oxidative stress, has been implicated in risk for preterm birth (PTB). OBJECTIVES: This study aimed to determine the association of maternal Cu concentration during pregnancy with PTB risk and gestational duration in a large multicohort study including diverse populations. METHODS: Maternal plasma or serum samples of 10,449 singleton live births were obtained from 18 geographically diverse study cohorts...
October 27, 2023: American Journal of Clinical Nutrition
#8
JOURNAL ARTICLE
Holly B Schuh, Shubhada Hooli, Salahuddin Ahmed, Carina King, Arunangshu D Roy, Norman Lufesi, Asmd Ashraful Islam, Tisungane Mvalo, Nabidul H Chowdhury, Amy Ginsburg, Tim Colbourn, William Checkley, Abdullah H Baqui, Eric D McCollum
BACKGROUND: Pulse oximeters are not routinely available in outpatient clinics in low- and middle-income countries. We derived clinical scores to identify hypoxemic child pneumonia. METHODS: This was a retrospective pooled analysis of two outpatient datasets of 3-35 month olds with World Health Organization (WHO)-defined pneumonia in Bangladesh and Malawi. We constructed, internally validated, and compared fit & discrimination of four models predicting SpO2 < 93% and <90%: (1) Integrated Management of Childhood Illness guidelines, (2) WHO-composite guidelines, (3) Independent variable least absolute shrinkage and selection operator (LASSO); (4) Composite variable LASSO...
2023: Frontiers in Pediatrics
#9
JOURNAL ARTICLE
Camilo Espinosa, Said Mohammed Ali, Waqasuddin Khan, Rasheda Khanam, Jesmin Pervin, Joan T Price, Sayedur Rahman, Tarik Hasan, Salahuddin Ahmed, Rubhana Raqib, Monjur Rahman, Shaki Aktar, Muhammad I Nisar, Javairia Khalid, Usha Dhingra, Arup Dutta, Saikat Deb, Jeffrey S A Stringer, Ronald J Wong, Gary M Shaw, David K Stevenson, Gary L Darmstadt, Brice Gaudilliere, Abdullah H Baqui, Fyezah Jehan, Anisur Rahman, Sunil Sazawal, Bellington Vwalika, Nima Aghaeepour, Martin S Angst
BACKGROUND: Blood proteins are frequently measured in serum or plasma, because they provide a wealth of information. Differences in the ex vivo processing of serum and plasma raise concerns that proteomic health and disease signatures derived from serum or plasma differ in content and quality. However, little is known about their respective power to predict feto-maternal health outcomes. Predictive power is a sentinel characteristic to determine the clinical use of biosignatures. OBJECTIVE: This study aimed to compare the power of serum and plasma proteomic signatures to predict a physiological pregnancy outcome...
August 2023: AJOG global reports
#10
JOURNAL ARTICLE
Hasan Mahmud Reza, Farhana Sultana, Razmin Bari, Jennifer Cole, Abdullah H Baqui
No abstract text is available yet for this article.
April 2023: Lancet Reg Health Southeast Asia
#11
JOURNAL ARTICLE
Camilo A Espinosa, Waqasuddin Khan, Rasheda Khanam, Sayan Das, Javairia Khalid, Jesmin Pervin, Margaret P Kasaro, Kévin Contrepois, Alan L Chang, Thanaphong Phongpreecha, Basil Michael, Mathew Ellenberger, Usma Mehmood, Aneeta Hotwani, Ambreen Nizar, Furqan Kabir, Ronald J Wong, Martin Becker, Eloise Berson, Anthony Culos, Davide De Francesco, Samson Mataraso, Neal Ravindra, Melan Thuraiappah, Maria Xenochristou, Ina A Stelzer, Ivana Marić, Arup Dutta, Rubhana Raqib, Salahuddin Ahmed, Sayedur Rahman, A S M Tarik Hasan, Said M Ali, Mohamed H Juma, Monjur Rahman, Shaki Aktar, Saikat Deb, Joan T Price, Paul H Wise, Virginia D Winn, Maurice L Druzin, Ronald S Gibbs, Gary L Darmstadt, Jeffrey C Murray, Jeffrey S A Stringer, Brice Gaudilliere, Michael P Snyder, Martin S Angst, Anisur Rahman, Abdullah H Baqui, Fyezah Jehan, Muhammad Imran Nisar, Bellington Vwalika, Sunil Sazawal, Gary M Shaw, David K Stevenson, Nima Aghaeepour
Preterm birth (PTB) is the leading cause of death in children under five, yet comprehensive studies are hindered by its multiple complex etiologies. Epidemiological associations between PTB and maternal characteristics have been previously described. This work used multiomic profiling and multivariate modeling to investigate the biological signatures of these characteristics. Maternal covariates were collected during pregnancy from 13,841 pregnant women across five sites. Plasma samples from 231 participants were analyzed to generate proteomic, metabolomic, and lipidomic datasets...
May 24, 2023: Science Advances
#12
JOURNAL ARTICLE
Elizabeth A Hazel, Daniel J Erchick, Joanne Katz, Anne C C Lee, Michael Diaz, Lee S F Wu, Keith P West, Abu Ahmed Shamim, Parul Christian, Hasmot Ali, Abdullah H Baqui, Samir K Saha, Salahuddin Ahmed, Arunangshu Dutta Roy, Mariângela F Silveira, Romina Buffarini, Roger Shapiro, Rebecca Zash, Patrick Kolsteren, Carl Lachat, Lieven Huybregts, Dominique Roberfroid, Zhonghai Zhu, Lingxia Zeng, Seifu H Gebreyesus, Kokeb Tesfamariam, Seth Adu-Afarwuah, Kathryn G Dewey, Stephaney Gyaase, Kwaku Poku-Asante, Ellen Boamah Kaali, Darby Jack, Thulasiraj Ravilla, James Tielsch, Sunita Taneja, Ranadip Chowdhury, Per Ashorn, Kenneth Maleta, Ulla Ashorn, Charles Mangani, Luke C Mullany, Subarna K Khatry, Vundli Ramokolo, Wanga Zembe-Mkabile, Wafaie W Fawzi, Dongqing Wang, Christentze Schmiegelow, Daniel Minja, Omari Abdul Msemo, John P A Lusingu, Emily R Smith, Honorati Masanja, Aroonsri Mongkolchati, Paniya Keentupthai, Abel Kakuru, Richard Kajubi, Katherine Semrau, Davidson H Hamer, Albert Manasyan, Jake M Pry, Bernard Chasekwa, Jean Humphrey, Robert E Black
OBJECTIVE: We aimed to understand the mortality risks of vulnerable newborns (defined as preterm and/or born weighing smaller or larger compared to a standard population), in low- and middle-income countries (LMICs). DESIGN: Descriptive multi-country, secondary analysis of individual-level study data of babies born since 2000. SETTING: Sixteen subnational, population-based studies from nine LMICs in sub-Saharan Africa, Southern and Eastern Asia, and Latin America...
May 8, 2023: BJOG: An International Journal of Obstetrics and Gynaecology
#13
JOURNAL ARTICLE
Tashnia Tahsin, Rasheda Khanam, Nabidul Haque Chowdhury, A S M Tarik Hasan, Md Biplob Hosen, Sayedur Rahman, Anjan Kumar Roy, Salahuddin Ahmed, Rubhana Raqib, Abdullah H Baqui
BACKGROUND: Each year, an estimated 15 million babies are born preterm. Micronutrient deficiencies, including vitamin D deficiency (VDD), are common in many low- and middle-income countries (LMICs), and these conditions are often associated with adverse pregnancy outcomes. Bangladesh experiences a high prevalence of VDD. The country also has a high preterm birth (PTB) rate. Using data from a population-based pregnancy cohort, we estimated the burden of VDD during pregnancy and its association with PTB...
May 6, 2023: BMC Pregnancy and Childbirth
#14
JOURNAL ARTICLE
Eric D McCollum, Salahuddin Ahmed, Arunangshu D Roy, Asmd Ashraful Islam, Holly B Schuh, Carina King, Shubhada Hooli, Mohammad Abdul Quaiyum, Amy Sarah Ginsburg, William Checkley, Abdullah H Baqui, Tim Colbourn
BACKGROUND: Hypoxaemic pneumonia mortality risk in low-income and middle-income countries is high in children who have been hospitalised, but unknown among outpatient children. We sought to establish the outpatient burden, mortality risk, and prognostic accuracy of death from hypoxaemia in children with suspected pneumonia in Bangladesh. METHODS: We conducted a prospective community-based cohort study encompassing three upazila (subdistrict) health complex catchment areas in Sylhet, Bangladesh...
April 7, 2023: Lancet Respiratory Medicine
#15
JOURNAL ARTICLE
Ahad Mahmud Khan, Saima Sultana, Salahuddin Ahmed, Ting Shi, Eric D McCollum, Abdullah H Baqui, Steve Cunningham, Harry Campbell
BACKGROUND: Non-physician health workers play a vital role in diagnosing and treating pneumonia in children in low- and middle-income countries (LMICs). Chest indrawing is a key indicator for pneumonia diagnosis, signifying the severity of the disease. We conducted this systematic review to summarize the evidence on non-physician health workers' ability to identify chest indrawing to detect pneumonia in children below five years of age in LMICs. METHODS: We comprehensively searched four electronic databases, including MEDLINE, Embase, Web of Science, and Scopus, and reference lists from the identified studies, from January 1, 1990, to January 20, 2022, with no language restrictions...
February 3, 2023: Journal of Global Health
#16
JOURNAL ARTICLE
Vanessa Cavallera, Gillian Lancaster, Melissa Gladstone, Maureen M Black, Gareth McCray, Ambreen Nizar, Salahuddin Ahmed, Arup Dutta, Romuald Kouadio E Anago, Alexandra Brentani, Fan Jiang, Yvonne Schönbeck, Dana C McCoy, Patricia Kariger, Ann M Weber, Abbie Raikes, Marcus Waldman, Stef van Buuren, Raghbir Kaur, Michelle Pérez Maillard, Muhammad Imran Nisar, Rasheda Khanam, Sunil Sazawal, Arsène Zongo, Mariana Pacifico Mercadante, Yunting Zhang, Arunangshu D Roy, Katelyn Hepworth, Günther Fink, Marta Rubio-Codina, Fahmida Tofail, Iris Eekhout, Jonathan Seiden, Rebecca Norton, Abdullah H Baqui, Jamila Khalfan Ali, Jin Zhao, Andreas Holzinger, Symone Detmar, Samuel Nzale Kembou, Farzana Begum, Said Mohammed Ali, Fyezah Jehan, Tarun Dua, Magdalena Janus
INTRODUCTION: Children's early development is affected by caregiving experiences, with lifelong health and well-being implications. Governments and civil societies need population-based measures to monitor children's early development and ensure that children receive the care needed to thrive. To this end, the WHO developed the Global Scales for Early Development (GSED) to measure children's early development up to 3 years of age. The GSED includes three measures for population and programmatic level measurement: (1) short form (SF) (caregiver report), (2) long form (LF) (direct administration) and (3) psychosocial form (PF) (caregiver report)...
January 24, 2023: BMJ Open
#17
JOURNAL ARTICLE
Nadia Ansari, Muhammad I Nisar, Farah Khalid, Usma Mehmood, Asra A Usmani, Fariha Shaheen, Aneeta Hotwani, Kehkashan Begum, Amina Barkat, Sachiyo Yoshida, Alexander A Manu, Sunil Sazawal, Abdullah H Baqui, Rajiv Bahl, Fyezah Jehan
BACKGROUND: Population-based seroepidemiological surveys provide accurate estimates of disease burden. We compare the COVID-19 prevalence estimates from two serial serological surveys and the associated risk factors among women and children in a peri-urban area of Karachi, Pakistan. METHODS: The AMANHI-COVID-19 study enrolled women and children between November 2020 and March 2021. Blood samples were collected from March to June 2021 (baseline) and September to December 2021 (follow-up) to test for anti-SARS-CoV-2 antibodies using ROCHE Elecsys®...
December 17, 2022: Journal of Global Health
#18
JOURNAL ARTICLE
Adrien Lokangaka Longombe, Adejumoke Idowu Ayede, Irene Marete, Fatima Mir, Clara Ladi Ejembi, Mohammod Shahidullah, Ebunoluwa A Adejuyigbe, Robinson D Wammanda, Antoinette Tshefu, Fabian Esamai, Anita K Zaidi, Abdullah H Baqui, Simon Cousens
Background: Hospital referral and admission in many- low and middle-income countries are not feasible for many young infants with sepsis/possible serious bacterial infection (PSBI). The effectiveness of simplified antibiotic regimens when referral to a hospital was not feasible has been shown before. We analysed the pooled data from the previous trials to compare the risk of poor clinical outcome for young infants with PSBI with the two regimens containing injectable procaine penicillin and gentamicin with the oral amoxicillin plus gentamicin regimen currently recommended by the World Health Organization (WHO) when referral is not feasible...
November 21, 2022: Journal of Global Health
#19
Kévin Contrepois, Songjie Chen, Mohammad S Ghaemi, Ronald J Wong, Fyezah Jehan, Sunil Sazawal, Abdullah H Baqui, Jeffrey S A Stringer, Anisur Rahman, Muhammad I Nisar, Usha Dhingra, Rasheda Khanam, Muhammad Ilyas, Arup Dutta, Usma Mehmood, Saikat Deb, Aneeta Hotwani, Said M Ali, Sayedur Rahman, Ambreen Nizar, Shaali M Ame, Sajid Muhammad, Aishwarya Chauhan, Waqasuddin Khan, Rubhana Raqib, Sayan Das, Salahuddin Ahmed, Tarik Hasan, Javairia Khalid, Mohammed H Juma, Nabidul H Chowdhury, Furqan Kabir, Fahad Aftab, Abdul Quaiyum, Alexander Manu, Sachiyo Yoshida, Rajiv Bahl, Jesmin Pervin, Joan T Price, Monjur Rahman, Margaret P Kasaro, James A Litch, Patrick Musonda, Bellington Vwalika, Gary Shaw, David K Stevenson, Nima Aghaeepour, Michael P Snyder
No abstract text is available yet for this article.
November 17, 2022: Scientific Reports
#20
JOURNAL ARTICLE
Ahad Mahmud Khan, Salahuddin Ahmed, Nabidul Haque Chowdhury, Md Shafiqul Islam, Eric D McCollum, Carina King, Ting Shi, Kamrun Nahar, Robynne Simpson, Ayaz Ahmed, Md Mozibur Rahman, Abdullah H Baqui, Steve Cunningham, Harry Campbell
INTRODUCTION: Manual counting of respiratory rate (RR) in children is challenging for health workers and can result in misdiagnosis of pneumonia. Some novel RR counting devices automate the counting of RR and classification of fast breathing. The absence of an appropriate reference standard to evaluate the performance of these devices is a challenge. If good quality videos could be captured, with RR interpretation from these videos systematically conducted by an expert panel, it could act as a reference standard...
November 15, 2022: BMJ Open
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