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https://www.readbyqxmd.com/read/28802197/enhanced-electrochemical-performance-of-nickel-cobalt-oxide-reduced-graphene-oxide-activated-carbon-asymmetric-supercapacitors-by-the-addition-of-a-redox-active-electrolyte
#1
Charmaine Lamiel, Yong Rok Lee, Moo Hwan Cho, Dirk Tuma, Jae-Jin Shim
Supercapacitors are an emerging energy-storage system with a wide range of potential applications. In this study, highly porous nickel-cobalt-oxide@reduced graphene oxide (Ni-Co-O@RGO-s) nanosheets were synthesized as an active material for supercapacitors using a surfactant-assisted microwave irradiation technique. The RGO-modified nanocomposite showed a larger specific area, better conductivity, and lower resistivity than the unmodified nanocomposite because the RGO facilitated faster ion diffusion/transport for improved redox activity...
August 2, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28796875/optical-coherence-tomography-analysis-based-prediction-of-humphrey-24-2-visual-field-thresholds-in-patients-with-glaucoma
#2
Zhihui Guo, Young H Kwon, Kyungmoo Lee, Kai Wang, Andreas Wahle, Wallace L M Alward, John H Fingert, Daniel I Bettis, Chris A Johnson, Mona K Garvin, Milan Sonka, Michael D Abràmoff
Purpose: A pilot study showed that prediction of individual Humphrey 24-2 visual field (HVF 24-2) sensitivity thresholds from optical coherence tomography (OCT) image analysis is possible. We evaluate performance of an improved approach as well as 3 other predictive algorithms on a new, fully independent set of glaucoma subjects. Methods: Subjects underwent HVF 24-2 and 9-field OCT (Heidelberg Spectralis) testing. Nerve fiber (NFL), and ganglion cell and inner plexiform (GCL+IPL) layers were cosegmented and partitioned into 52 sectors matching HVF 24-2 test locations...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28796752/a-new-approach-for-the-determination-of-dose-rate-and-radioactivity-for-detected-gamma-nuclides-using-an-environmental-radiation-monitor-based-on-an-nai-tl-detector
#3
Young-Yong Ji, Chang-Jong Kim, Kyo-Sun Lim, Wanno Lee, Hyon-Sock Chang, Kun Ho Chung
To expand the application of dose rate spectroscopy to the environment, the method using an environmental radiation monitor (ERM) based on a 3' × 3' NaI(Tl) detector was used to perform real-time monitoring of the dose rate and radioactivity for detected gamma nuclides in the ground around an ERM. Full-energy absorption peaks in the energy spectrum for dose rate were first identified to calculate the individual dose rates of Bi, Ac, Tl, and K distributed in the ground through interference correction because of the finite energy resolution of the NaI(Tl) detector used in an ERM...
August 7, 2017: Health Physics
https://www.readbyqxmd.com/read/28789929/commentary-on-comprehensive-transcriptional-analysis-of-early-stage-urothelial-carcinoma-hedegaard-j-lamy-p-nordentoft-i-algaba-f-h%C3%A3-yer-s-ulh%C3%A3-i-bp-vang-s-reinert-t-hermann-gg-mogensen-k-thomsen-mb-nielsen-mm-marquez-m-segersten-u-aine-m-h%C3%A3-glund-m-birkenkamp
#4
Byron H Lee
Non-muscle-invasive bladder cancer (NMIBC) is a heterogeneous disease with widely different outcomes. We performed a comprehensive transcriptional analysis of 460 early-stage urothelial carcinomas and showed that NMIBC can be subgrouped into 3 major classes with basal- and luminal-like characteristics and different clinical outcomes. Large differences in biological processes such as the cell cycle, epithelial-mesenchymal transition, and differentiation were observed. Analysis of transcript variants revealed frequent mutations in genes encoding proteins involved in chromatin organization and cytoskeletal functions...
August 5, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28782367/diagnostic-imaging-pediatrics-ac-merrow-jr-diagnostic-imaging-pediatrics-3rd-edition-elsevier-london-2017-1312-pp-978-0-323-44306-7-us-339-99-hbk
#5
Abbey J Winant, Edward Y Lee
No abstract text is available yet for this article.
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28774159/comparison-of-changes-in-the-interstitial-cells-of-cajal-and-neuronal-nitric-oxide-synthase-positive-neuronal-cells-with-aging-between-the-ascending-and-descending-colon-of-f344-rats
#6
Sun Min Lee, Nayoung Kim, Hyun Jin Jo, Ji Hyun Park, Ryoung Hee Nam, Hye Seung Lee, Hyun Jin Kim, Moon Young Lee, Yong Sung Kim, Dong Ho Lee
Background/Aims: Neuronal degeneration and changes in interstitial cells of Cajal (ICCs) are important mechanisms of age-related constipation. This study aims to compare the distribution of ICCs and neuronal nitric oxide synthase (nNOS) with regard to age-related changes between the ascending colon (AC) and descending colon (DC) in 6-, 31-, and 74-week old and 2-year old male Fischer-344 rats. Methods: The amount of fecal pellet and the bead expulsion times were measured...
August 4, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28768057/memory-integration-in-humans-with-hippocampal-lesions
#7
Anna Pajkert, Carsten Finke, Yee-Lee Shing, Martina Hoffmann, Werner Sommer, Hauke R Heekeren, Christoph J Ploner
Adaptive behavior frequently depends on inference from past experience. Recent studies suggest that the underlying process of integrating related memories may depend on interaction between hippocampus and prefrontal cortex. Here, we investigated how hippocampal damage affects memory integration. Subjects with mediotemporal lesions and healthy controls learned a set of overlapping AB- and BC-associations (object-face- and face-object pairs) and were then tested for memory of these associations ('direct' trials) and of inferential AC-associations ('indirect' trials)...
August 2, 2017: Hippocampus
https://www.readbyqxmd.com/read/28766235/polymorphisms-in-epithelial-mesenchymal-transition-related-genes-and-the-prognosis-of-surgically-treated-non-small-cell-lung-cancer
#8
Yangki Seok, Hyo-Gyoung Kang, Shin Yup Lee, Ji Yun Jeong, Jin Eun Choi, Deuk Kju Jung, Cheng Cheng Jin, Mi Jeong Hong, Sook Kyung Do, Won Kee Lee, Ji Young Park, Kyung Min Shin, Seung Soo Yoo, Jaehee Lee, Sukki Cho, Seung Ick Cha, Chang Ho Kim, Sanghoon Jheon, Eung Bae Lee, Jae Yong Park
BACKGROUND: This study was conducted to determine whether single-nucleotide polymorphisms (SNPs) in EMT-related genes may influence the prognosis of NSCLC after surgery. METHODS: There were 88 SNPs in EMT-related genes evaluated in a discovery set of 376 patients who underwent curative surgery for NSCLC. Significantly, 14 SNPs were evaluated in a validation set of 428 patients. Luciferase assay and RT-PCR were conducted to examine functional relevance of polymorphisms...
August 1, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28749987/dude-seq-fast-flexible-and-robust-denoising-for-targeted-amplicon-sequencing
#9
Byunghan Lee, Taesup Moon, Sungroh Yoon, Tsachy Weissman
We consider the correction of errors from nucleotide sequences produced by next-generation targeted amplicon sequencing. The next-generation sequencing (NGS) platforms can provide a great deal of sequencing data thanks to their high throughput, but the associated error rates often tend to be high. Denoising in high-throughput sequencing has thus become a crucial process for boosting the reliability of downstream analyses. Our methodology, named DUDE-Seq, is derived from a general setting of reconstructing finite-valued source data corrupted by a discrete memoryless channel and effectively corrects substitution and homopolymer indel errors, the two major types of sequencing errors in most high-throughput targeted amplicon sequencing platforms...
2017: PloS One
https://www.readbyqxmd.com/read/28748491/polyurethane-meniscal-scaffolds-lead-to-better-clinical-outcomes-but-worse-articular-cartilage-status-and-greater-absolute-meniscal-extrusion
#10
Young-Soo Shin, Hoon-Nyun Lee, Hyun-Bo Sim, Hyun-Jung Kim, Dae-Hee Lee
PURPOSE: Implantation of polyurethane (PU) meniscal scaffolds has become a popular procedure to provide a scaffold for vessel ingrowth and meniscal tissue regeneration in patients with partial meniscal defects. However, it is unclear whether PU meniscal scaffolds lead to better clinical and magnetic resonance imaging (MRI) outcomes post-operatively. This meta-analysis compared the clinical and MRI outcomes in patients with partial meniscal defects treated with PU meniscal scaffolds. METHODS: This meta-analysis reviewed all studies that assessed Lysholm score, International Knee Documentation Committee (IKDC) score, visual analogue scale (VAS) for pain, Tegner score, Knee Injury and Osteoarthritis Outcomes Score (KOOS), articular cartilage (AC), absolute meniscal extrusion (AME), morphology and size (MS), signal intensity (SI) of meniscal implant, and interface of the implant-residual meniscus complex (IIRMC) in patients with partial meniscal defects treated with PU meniscal scaffolds...
July 26, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28730619/real-world-adherence-and-persistence-with-direct-oral-anticoagulants-in-adults-with-atrial-fibrillation
#11
Beenish S Manzoor, Todd A Lee, Lisa K Sharp, Surrey M Walton, William L Galanter, Edith A Nutescu
BACKGROUND: Evidence of adherence and persistence patterns in anticoagulation (AC) therapy comparing treatment-naïve and non-naïve patients is lacking. The objective of this study was to evaluate patterns of medication adherence and persistence in a real-world setting among AC-naïve and AC-experienced atrial fibrillation (AF) patients treated with direct oral anticoagulants (DOACs). METHODS: AF patients newly initiating a DOAC with a minimum of 6 months of continuous health plan enrollment pre and post-index date (first DOAC prescription) were identified from the Truven Health MarketScan(®) Commercial and Medicare Supplemental databases (2009-2013)...
July 21, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28729060/correlation-of-joint-volume-and-passive-range-of-motion-with-capsulo-synovial-thickness-measured-by-contrast-enhanced-magnetic-resonance-imaging-in-adhesive-capsulitis
#12
Yong-Taek Lee, Kwang-Soo Chun, Kyung Jae Yoon, Hee-Jin Park, So-Yeon Lee, Eugene Kim, Young Sook Park, Kyoung-Ho Seo
BACKGROUND: No study has investigated the relationship between the findings of contrast-enhanced magnetic resonance imaging (CE-MRI) and the joint volume of the shoulder, which has been considered the standard reference for diagnosis of adhesive capsulitis (AC). OBJECTIVE: To investigate the relationships among the capsulo-synovial thickness measured by CE-MRI, joint volume, and passive range of motion (ROM) in patients with AC. DESIGN: This was a retrospective study...
July 17, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28726370/ultrastretchable-analog-digital-signal-transmission-line-with-carbon-nanotube-sheets
#13
Yourack Lee, Min-Kyu Joo, Viet Thong Le, Raquel Ovalle-Robles, Xavier Lepró, Márcio D Lima, Daniel G Suh, Han Young Yu, Young Hee Lee, Dongseok Suh
Stretchable conductors can be used in various applications depending on their own characteristics. Here, we demonstrate simple and robust elastomeric conductors that are optimized for stretchable electrical signal transmission line. They can withstand strains up to 600% without any substantial change in their resistance (≤10% as is and ≤1% with passivation), and exhibit suppressed charge fluctuations in the medium. The inherent elasticity of a polymeric rubber and the high conductivity of flexible, highly oriented carbon nanotube sheets were combined synergistically, without losing both properties...
August 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28697684/what-is-the-accuracy-of-an-early-third-trimester-sonogram-for-identifying-lga-infants-born-to-gdm-patients-diagnosed-with-the-one-step-approach
#14
Kelsey J Simpson, Meredith Pavicic, Gene T Lee
PURPOSE: The one-step approach for screening of GDM will increase the incidence 2- to 3-fold. These larger cohorts may need to target high-morbidity subsets to be cost-effective. We asked whether ultrasound could stratify the GDM patients with the highest risk for a large for gestational age (LGA) infant. MATERIALS AND METHODS: A retrospective analysis was performed on 413 GDM patients diagnosed using the one-step approach. Ultrasound data from 28 weeks 0 day to 34 weeks 6 days was studied...
July 11, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28695621/molecular-design-of-thermally-activated-delayed-fluorescent-emitters-using-2-2-bipyrimidine-as-an-acceptor-in-donor-acceptor-structure
#15
Hee-Jun Park, Si Hyun Han, Jun Yeob Lee
D-A-D type thermally activated delayed fluorescence (TADF) emitters, 5,5'-bis(4-(9,9-dimethylacridin-10(9H)-yl)phenyl)-2,2'-bipyrimidine (Ac-bpm) and 5,5'-bis(4-(10H-phenoxazin-10-yl)phenyl)-2,2'-bipyrimidine (Px-bpm), based on 2,2'-bipyrimidine accepting unit were developed and their TADF devices were fabricated. The orthogonal geometry between the donor unit and the 2,2'-bipyrimidine accepting core facilitated a HOMO/LUMO spatial separation, thus realizing thermally activated delayed fluorescence. They exhibited electroluminescence ranging from green to yellow, depending on the donor unit, with a maximum external quantum efficiencies of up to 17...
July 11, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28689855/planyourlifespan-org-an-intervention-to-help-seniors-make-choices-for-their-fourth-quarter-of-life-results-from-the-randomized-clinical-trial
#16
Lee A Lindquist, Vanessa Ramirez-Zohfeld, Priya D Sunkara, Chris Forcucci, Dianne S Campbell, Phyllis Mitzen, Jody D Ciolino, Dyanna Gregory, Gayle Kricke, Kenzie A Cameron
OBJECTIVE: Few older adults contemplate their home support and health needs that may be required for aging-in-place. We sought to assess the efficacy of PlanYourLifespan.org (PYL), in influencing seniors' planning behaviors, perception of the importance of planning, and confidence accessing services. METHOD: Randomized controlled trial, of adults, age ≥65 years in urban, suburban, rural areas of Texas, Illinois, Indiana. RESULTS: Among 385 participants, mean age was 71...
June 27, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28689661/nuclear-acetyl-coa-production-by-acly-promotes-homologous-recombination
#17
Sharanya Sivanand, Seth Rhoades, Qinqin Jiang, Joyce V Lee, Joseph Benci, Jingwen Zhang, Salina Yuan, Isabella Viney, Steven Zhao, Alessandro Carrer, Michael J Bennett, Andy J Minn, Aalim M Weljie, Roger A Greenberg, Kathryn E Wellen
While maintaining the integrity of the genome and sustaining bioenergetics are both fundamental functions of the cell, potential crosstalk between metabolic and DNA repair pathways is poorly understood. Since histone acetylation plays important roles in DNA repair and is sensitive to the availability of acetyl coenzyme A (acetyl-CoA), we investigated a role for metabolic regulation of histone acetylation during the DNA damage response. In this study, we report that nuclear ATP-citrate lyase (ACLY) is phosphorylated at S455 downstream of ataxia telangiectasia mutated (ATM) and AKT following DNA damage...
July 20, 2017: Molecular Cell
https://www.readbyqxmd.com/read/28687744/ccm111-the-water-extract-of-antrodia-cinnamomea-regulates-immune-related-activity-through-stat3-and-nf-%C3%AE%C2%BAb-pathways
#18
In-Yu Lin, Min-Hsiung Pan, Ching-Shu Lai, Ting-Ting Lin, Chiung-Tong Chen, Tao-Sheng Chung, Chien-Lung Chen, Chen-Huan Lin, Wu-Chang Chuang, Ming-Chung Lee, Ching-Che Lin, Nianhan Ma
Antrodia cinnamomea (AC) exhibits many bioactivities, including anti-inflammatory, anti-cancer, and hepatoprotection activities. Many researchers have studied the functions of the components or fractions of AC, but the functions of the original extractions of AC have not been studied. In addition, the detailed relationship between AC and immune-related signaling pathways is unclear. In this study, we screened the effects of CCM111, which is the extract of AC, on seven immune-related signaling pathways and further investigated whether CCM111 can influence inflammation...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28681155/analysis-of-perioperative-chemotherapy-in-resected-pancreatic-cancer-identifying-the-number-and-sequence-of-chemotherapy-cycles-needed-to-optimize-survival
#19
Irene Epelboym, Mazen S Zenati, Ahmad Hamad, Jennifer Steve, Kenneth K Lee, Nathan Bahary, Melissa E Hogg, Herbert J Zeh, Amer H Zureikat
PURPOSE: Receipt of 6 cycles of adjuvant chemotherapy (AC) is standard of care in pancreatic cancer (PC). Neoadjuvant chemotherapy (NAC) is increasingly utilized; however, optimal number of cycles needed alone or in combination with AC remains unknown. We sought to determine the optimal number and sequence of perioperative chemotherapy cycles in PC. METHODS: Single institutional review of all resected PCs from 2008 to 2015. The impact of cumulative number of chemotherapy cycles received (0, 1-5, and ≥6 cycles) and their sequence (NAC, AC, or NAC + AC) on overall survival was evaluated Cox-proportional hazard modeling, using 6 cycles of AC as reference...
July 5, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28680265/rapanet-a-web-tool-for-the-co-expression-analysis-of-brassica-rapa-genes
#20
Jiye Kim, Kyong Mi Jun, Joung Sug Kim, Songhwa Chae, Yoon-Mok Pahk, Tae-Ho Lee, Soo-In Sohn, Soo In Lee, Myung-Ho Lim, Chang-Kug Kim, Yoonkang Hur, Baek Hie Nahm, Yeon-Ki Kim
Accumulated microarray data are used for assessing gene function by providing statistical values for co-expressed genes; however, only a limited number of Web tools are available for analyzing the co-expression of genes of Brassica rapa. We have developed a Web tool called RapaNet (http://bioinfo.mju.ac.kr/arraynet/brassica300k/query/), which is based on a data set of 143 B rapa microarrays compiled from various organs and at different developmental stages during exposure to biotic or abiotic stress. RapaNet visualizes correlated gene expression information via correlational networks and phylogenetic trees using Pearson correlation coefficient (r)...
2017: Evolutionary Bioinformatics Online
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