keyword
https://read.qxmd.com/read/38599453/a-novel-classification-of-intraoperative-ulnar-nerve-instability-to-aid-transposition-surgery
#1
JOURNAL ARTICLE
Nicholas Pohl, Parker Brush, Daren Aita, Justin Kistler, Christopher Jones, Rick Tosti, Daniel Fletcher
HYPOTHESIS: The purpose of this study was to compare inter-and intraobserver agreement of a novel intraoperative subluxation classification for patients undergoing ulnar nerve surgery at the elbow. We hypothesize there will be strong inter- and intraobserver agreement of the four-category classification system and reviewers will have substantial confidence while reviewing the classification system. METHODS: Four blinded fellowship-trained orthopedic hand surgeons reviewed 25 videos in total on two separate viewings, 21 days apart...
April 8, 2024: Journal of Shoulder and Elbow Surgery
https://read.qxmd.com/read/38588971/reproductive-toxicity-assessment-of-cellulose-nanofibers-citric-acid-and-branched-polyethylenimine-in-sea-urchins-eco-design-of-nanostructured-cellulose-sponge-framework-part-b
#2
JOURNAL ARTICLE
Maria Consiglia Esposito, Laura Riva, Gian Luigi Russo, Carlo Punta, Ilaria Corsi, Elisabetta Tosti, Alessandra Gallo
In the framework of a safe-by-design approach, we previously assessed the eco-safety of nanostructured cellulose sponge (CNS) leachate on sea urchin reproduction. It impaired gamete quality, gamete fertilization competence, and embryo development possibly due to the leaching of chemical additives deriving from their chemical synthesis. To extend this observation and identify the component(s) that contribute to CNS ecotoxicity, in the present study, we individually screened the cytotoxic effects on sea urchin Arbacia lixula and Paracentrotus lividus gametes and embryos of the three main constituents of CNS, namely cellulose nanofibers, citric acid, and branched polyethylenimine...
April 6, 2024: Environmental Pollution
https://read.qxmd.com/read/38571696/a-cross-sectional-observational-study-showing-sebaceous-glands-differences-between-psoriatic-alopecia-and-alopecia-areata
#3
JOURNAL ARTICLE
Betty Nguyen, Curtis T Thompson, Antonella Tosti
No abstract text is available yet for this article.
June 2024: JAAD international
https://read.qxmd.com/read/38567285/integrated-use-of-biofeedback-and-neurofeedback-techniques-in-treating-pathological-conditions-and-improving-performance-a-narrative-review
#4
REVIEW
Beatrice Tosti, Stefano Corrado, Stefania Mancone, Tommaso Di Libero, Angelo Rodio, Alexandro Andrade, Pierluigi Diotaiuti
In recent years, the scientific community has begun tо explore the efficacy оf an integrated neurofeedback + biofeedback approach іn various conditions, both pathological and non-pathological. Although several studies have contributed valuable insights into its potential benefits, this review aims tо further investigate its effectiveness by synthesizing current findings and identifying areas for future research. Our goal іs tо provide a comprehensive overview that may highlight gaps іn the existing literature and propose directions for subsequent studies...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38551554/correlating-cicatricial-alopecia-and-cardiovascular-risk-emerging-insights
#5
JOURNAL ARTICLE
Andrea Sechi, Antonella Tosti
No abstract text is available yet for this article.
March 26, 2024: Journal of Investigative Dermatology
https://read.qxmd.com/read/38542403/chemical-constituents-of-stinging-nettle-urtica-dioica-l-a-comprehensive-review-on-phenolic-and-polyphenolic-compounds-and-their-bioactivity
#6
REVIEW
Saša Đurović, Ivan Kojić, Danka Radić, Yulia A Smyatskaya, Julia G Bazarnova, Snežana Filip, Tomislav Tosti
Polyphenolic compounds are of great interest in today's science. Naturally, they occur in plants and other sources in many different forms. Their wide range of biological activity has attracted the attention of the scientific community. One of the sources of phenolic compounds is stinging nettle ( Urtica dioica L.), a common plant in almost all parts of the world. A long tradition of utilization and an interesting chemical profile make this plant a fascinating and extensive object of study. The chemical profile also allows this plant to be used as a food and a pigment source in the food, pharmaceutical, and cosmetic industries...
March 18, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38535733/improving-mental-skills-in-precision-sports-by-using-neurofeedback-training-a-narrative-review
#7
REVIEW
Stefano Corrado, Beatrice Tosti, Stefania Mancone, Tommaso Di Libero, Angelo Rodio, Alexandro Andrade, Pierluigi Diotaiuti
Primary objectives of neurofeedback training (NFT) are to improve concentration, stress and anxiety management, and performance optimisation. This narrative review examines the role of NFT as a tool to improve mental and cognitive skills of target shooting and archery athletes. Current research discusses how neurofeedback training can act on brain waves by influencing specific EEG frequency bands in order to improve cognitive flexibility. This contribution reports studies that have applied neurofeedback protocols in precision disciplines such as archery and shooting...
February 29, 2024: Sports
https://read.qxmd.com/read/38535233/the-effect-of-green-extraction-technologies-on-the-chemical-composition-of-medicinal-chaga-mushroom-extracts
#8
JOURNAL ARTICLE
Vesna Lazić, Anita Klaus, Maja Kozarski, Ana Doroški, Tomislav Tosti, Siniša Simić, Jovana Vunduk
The mushroom industry should implement green extraction technologies; however, there is not enough information on the differences between these techniques expressed as the chemical composition of the resulting extract. In this study, selected types of green extraction techniques (GETs) were used on Chaga ( Inonotus obliquus ) (Fr.) Pilát from Serbia (IS) and Mongolia (IM) to examine the differences that would enable the composition-based technology choices in the mushroom supplement industry. Subcritical water extraction (SWE), microwave-assisted (MW) extraction, and ultrasonic-assisted extraction (VAE) were used to prepare the extracts...
March 19, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38490877/extensor-tendon-transfer-for-fracture-related-extensor-pollicis-longus-rupture-long-term-outcome-case-series
#9
JOURNAL ARTICLE
Alexander J Adams, Saral J Patel, Sebastian D Arango, Kaleb Smithson, Rick J Tosti, Andrew J Miller
BACKGROUND: Spontaneous rupture of the extensor pollicis longus (EPL) tendon following both nonoperative and operative treatment of distal radius fractures has been well described. PURPOSE: The purpose of this study was to assess long-term outcomes of extensor indicis proprius to EPL tendon transfers for patients following distal radius fracture and EPL tendon repair. STUDY DESIGN: Retrospective case series focusing on long-term clinical outcomes...
March 14, 2024: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://read.qxmd.com/read/38469362/safety-and-efficacy-of-a-feed-additive-consisting-of-6-phytase-produced-by-aspergillus-oryzae-%C3%A2-dsm-33737-hiphorius%C3%A2-for-all-poultry-all-suidae-and-all-fin-fish-dsm-nutritional-products-ltd
#10
JOURNAL ARTICLE
Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Durjava, Maryline Kouba, Marta López-Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Noël Dierick, Henriqueta Louro, Giovanna Martelli, Luca Tosti, Montserrat Anguita, Joana P Firmino, Matteo L Innocenti, Elisa Petenatti, Fabiola Pizzo, Jordi Ortuño
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 6-phytase produced by the genetically modified strain Aspergillus oryzae DSM 33737 (HiPhorius™ 10, 40, 20L and 50L) as a zootechnical feed additive for all poultry, all Suidae and all fin fish. The FEEDAP Panel concluded that the genetic modification of the production strain does not give rise to safety concerns...
March 2024: EFSA journal
https://read.qxmd.com/read/38432192/characterization-of-a-flexible-a-si-h-detector-for-in-vivo-dosimetry-in-therapeutic-x-ray-beams
#11
JOURNAL ARTICLE
Matthew James Large, Aishah Bashiri, Yashiv Dookie, Joanne McNamara, Luca Antognini, Saba Aziz, Lucio Calcagnile, Anna Paola Caricato, Roberto Catalano, Deborah Chila, Giuseppe Antonio Pablo Cirrone, Tomasso Croci, Giacomo Cuttone, Sylvain Dunand, Michele Fabi, Luca Frontini, Catia Grimani, Maria Ionica, Keida Kanxheri, Valentino Liberali, Martino Maurizio, Giuseppe Maruccio, Giovanni Mazza, Mauro Menichelli, Anna Grazia Monteduro, Arianna Morozzi, Francesco Moscatelli, Stefania Pallotta, Daniele Passeri, Maddalena Pedio, Giada Petringa, Francesca Peverini, Lorenzo Piccolo, Pisana Placidi, Gianluca Quarta, Silvia Rizzato, Federico Sabbatini, Leonello Servoli, Alberto Stabile, Cinzia Talamonti, Jonathan Emanuel Thomet, Luca Tosti, Mattia Villani, Richard James Wheadon, Nicolas Wyrsch, Nicola Zema, Marco Petasecca
BACKGROUND: The increasing use of complex and high dose-rate treatments in radiation therapy necessitates advanced detectors to provide accurate dosimetry. Rather than relying on pre-treatment quality assurance (QA) measurements alone, many countries are now mandating the use of in vivo dosimetry, whereby a dosimeter is placed on the surface of the patient during treatment. Ideally, in vivo detectors should be flexible to conform to a patient's irregular surfaces. PURPOSE: This study aims to characterize a novel hydrogenated amorphous silicon (a-Si:H) radiation detector for the dosimetry of therapeutic x-ray beams...
March 3, 2024: Medical Physics
https://read.qxmd.com/read/38400108/exploring-covid-19-vaccination-willingness-in-italy-a-focus-on-resident-foreigners-and-italians-using-data-from-passi-and-passi-d-argento-surveillance-systems
#12
JOURNAL ARTICLE
Benedetta Contoli, Maria Elena Tosti, Federica Asta, Valentina Minardi, Giulia Marchetti, Virginia Casigliani, Salvatore Scarso, Silvia Declich, Maria Masocco
(1) The COVID-19 pandemic exacerbated health disparities, both between foreign and autochthonous populations. Italy was one of the European countries that was the most affected by the COVID-19 pandemic; however, only limited data are available on vaccine willingness. This study aims to assess the propensity of foreign and autochthonous populations residing in Italy to be vaccinated and the relative associated factors. (2) Data were collected and analysed from the two Italian surveillance systems, PASSI and PASSI d'Argento, in the period of August 2020-December 2021...
January 26, 2024: Vaccines
https://read.qxmd.com/read/38389727/an-organic-extract-from-ascidian-ciona-robusta-induces-cytotoxic-autophagy-in-human-malignant-cell-lines
#13
JOURNAL ARTICLE
Alessandra Gallo, Ylenia Maria Penna, Maria Russo, Marco Rosapane, Elisabetta Tosti, Gian Luigi Russo
The last decades have seen an increase in the isolation and characterization of anticancer compounds derived from marine organisms, especially invertebrates, and their use in clinical trials. In this regard, ascidians, which are included in the subphylum Tunicata, represent successful examples with two drugs, Aplidine© and Yondelis© that reached the market as orphan drugs against several malignancies. Here, we report that an organic extract prepared from homogenized tissues of the Mediterranean ascidian Ciona robusta inhibited cell proliferation in HT-29, HepG2, and U2OS human cells with the former being the most sensitive to the extract (EC50 = 250 μg/mL)...
2024: Frontiers in Chemistry
https://read.qxmd.com/read/38376087/low-dose-oral-minoxidil-for-alopecia-a-comprehensive-review
#14
JOURNAL ARTICLE
Aditya K Gupta, Mesbah Talukder, Avner Shemer, Bianca Maria Piraccini, Antonella Tosti
Low-dose oral minoxidil (LDOM) has demonstrated a promising safety and efficacy profile in the treatment of various hair disorders, including male androgenetic alopecia (AGA) and female-pattern hair loss (FPHL); however, it lacks FDA approval. The usual LDOM starting dose for male AGA is 1-5 mg/day, depending on physician preference and the patient's condition. For FPHL, it is 0.5-1 mg/day. The maximum dose is generally 5 mg/day. If patients respond well without major side effects, the dose may be gradually increased since the LDOM's efficacy appears to be dose-dependent...
December 2023: Skin Appendage Disorders
https://read.qxmd.com/read/38341148/treatment-for-central-centrifugal-cicatricial-alopecia-delphi-consensus-recommendations
#15
JOURNAL ARTICLE
Tiaranesha Jackson, Yacine Sow, Jewell Dinkins, Crystal Aguh, Katherine Omueti Ayoade, Victoria Barbosa, Cheryl Burgess, Valerie Callender, George Cotsarelis, Pearl Grimes, Valerie Harvey, Chesahna Kindred, Jenna Lester, Kristen Lo Sicco, Tiffany Mayo, Amy McMichael, Michelle Oboite, Temitayo Ogunleye, Elise Olsen, Achiamah Osei-Tutu, Melissa Piliang, Maryanne Senna, Jerry Shapiro, Antonella Tosti, Cheri Frey, Prince Adotama, Susan C Taylor
BACKGROUND: There is no established standard of care for treating central centrifugal cicatricial alopecia (CCCA), and treatment approaches vary widely. OBJECTIVE: To develop consensus statements regarding the use of various pharmacological therapies in treating adults with CCCA. METHODS: We invited 27 dermatologists with expertise in hair and scalp disorders to participate in a 3-round modified Delphi study between January and March 2023...
February 8, 2024: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/38324292/the-alopecia-areata-severity-and-morbidity-index-asami-study-results-from-a-global-expert-consensus-exercise-on-determinants-of-alopecia-areata-severity
#16
JOURNAL ARTICLE
Anthony Moussa, Michaela Bennett, Dmitri Wall, Nekma Meah, Katherine York, Laita Bokhari, Leila Asfour, Huw Rees, Leonardo Spagnol Abraham, Daniel Asz-Sigall, Fitnat Buket Basmanav, Wilma Bergfeld, Regina C Betz, Bevin Bhoyrul, Ulrike Blume-Peytavi, Valerie Callender, Vijaya Chitreddy, Andrea Combalia, George Cotsarelis, Brittany Craiglow, Rachita Dhurat, Jeff Donovan, Andrei Doroshkevich, Samantha Eisman, Paul Farrant, Juan Ferrando, Aida Gadzhigoroeva, Jack Green, Ramon Grimalt, Matthew Harries, Maria Hordinsky, Alan Irvine, Victoria Jolliffe, Spartak Kaiumov, Brett King, Joyce Lee, Won-Soo Lee, Jane Li, Nino Lortkipanidze, Amy McMichael, Natasha Atanaskova Mesinkovska, Andrew Messenger, Paradi Mirmirani, Elise Olsen, Seth J Orlow, Yuliya Ovcharenko, Bianca Maria Piraccini, Rodrigo Pirmez, Adriana Rakowska, Pascal Reygagne, Lidia Rudnicka, David Saceda Corralo, Maryanne Senna, Jerry Shapiro, Pooja Sharma, Tatiana Siliuk, Michela Starace, Poonkiat Suchonwanit, Anita Takwale, Antonella Tosti, Sergio Vañó-Galván, Willem I Visser, Annika Vogt, Martin Wade, Leona Yip, Cheng Zhou, Rodney Sinclair
IMPORTANCE: Current measures of alopecia areata (AA) severity, such as the Severity of Alopecia Tool score, do not adequately capture overall disease impact. OBJECTIVE: To explore factors associated with AA severity beyond scalp hair loss, and to support the development of the Alopecia Areata Severity and Morbidity Index (ASAMI). EVIDENCE REVIEW: A total of 74 hair and scalp disorder specialists from multiple continents were invited to participate in an eDelphi project consisting of 3 survey rounds...
February 7, 2024: JAMA Dermatology
https://read.qxmd.com/read/38313570/hair-to-hair-trichoscopy-an-objective-method-to-assess-effectiveness-of-botulinum-toxin-in-a-clinical-trial-for-androgenetic-alopecia
#17
JOURNAL ARTICLE
Daniel Fernandes Melo, André Luiz Vairo Donda, Rita Fernanda Cortez de Almeida, Daniela Alves Pereira Antelo, Paulo Muller-Ramos, Carla Jorge Machado, Sidney Frattini, Antonella Tosti, Carlos Baptista Barcaui
INTRODUCTION: Androgenetic alopecia (AGA) is the most common alopecia affecting both genders leading to a potential decrease in quality of life and self-esteem. A current concern in trichology is how to accurately measure clinical response in both daily medical practice and academic research. Hair-to-hair (H2H)-matching technology™ has recently emerged as a technique to evaluate variations in follicular units, hair shaft number, and thickness. This study aimed to describe the methodology employed in a clinical trial using this technology to test the efficacy of botulinum toxin (BT) for male AGA...
February 2024: Skin Appendage Disorders
https://read.qxmd.com/read/38274395/teledermatology-in-alopecia-a%C3%A2-systematic-review
#18
JOURNAL ARTICLE
Narges Maskan Bermudez, Sofia Perez, Betty Nguyen, Antonella Tosti
No abstract text is available yet for this article.
March 2024: JAAD international
https://read.qxmd.com/read/38217053/a-cross-sectional-analysis-of-medications-used-by-patients-reporting-alopecia-areata-on-the-fda-adverse-events-reporting-system
#19
JOURNAL ARTICLE
Advaitaa Ravipati, Tejus Pradeep, Antonella Tosti
BACKGROUND: Alopecia areata (AA) is an autoimmune condition that leads to patchy, nonscarring hair loss. Its etiology remains unknown; the condition can be debilitating for patients, impacting their psychosocial wellbeing. Various triggers have been reported, ranging from genetic predisposition and infections to environmental factors. Medications have also been thought to be an inciting factor in AA. METHODS: Using the Food and Drug Administration (FDA) Adverse Events Reporting System (FAERS), all cases reporting AA as an adverse event were used to capture associated medications and patient characteristics...
January 12, 2024: International Journal of Dermatology
https://read.qxmd.com/read/38214375/treatment-of-onychomycosis-in-an-era-of-antifungal-resistance-role-for-antifungal-stewardship-and-topical-antifungal-agents
#20
REVIEW
Aditya K Gupta, Boni Elewski, Warren S Joseph, Shari R Lipner, C Ralph Daniel, Antonella Tosti, Eric Guenin, Mahmoud Ghannoum
A growing body of literature has marked the emergence and spread of antifungal resistance among species of Trichophyton, the most prevalent cause of toenail and fingernail onychomycosis in the United States and Europe. We review published data on rates of oral antifungal resistance among Trichophyton species; causes of antifungal resistance and methods to counteract it; and in vitro data on the role of topical antifungals in the treatment of onychomycosis. Antifungal resistance among species of Trichophyton against terbinafine and itraconazole-the two most common oral treatments for onychomycosis and other superficial fungal infections caused by dermatophytes-has been detected around the globe...
January 2024: Mycoses
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