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https://www.readbyqxmd.com/read/22552797/which-stages-of-thymoma-benefit-from-adjuvant-chemotherapy-post-thymectomy
#1
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Saina Attaran, David McCormack, John Pilling, Karen Harrison-Phipps
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was 'Which stages of thymoma benefit from adjuvant chemotherapy post thymectomy?' Altogether more than 150 papers were found using the reported search, of which only eight represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated; these studies have mainly reported the survival and recurrence rates of post-thymectomy patients who received adjuvant radiotherapy or chemoradiotherapy, and adjuvant radiotherapy alone was only used in a small group of patients in these studies...
August 2012: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/18769562/acceptability-of-cancer-chemoprevention-trials-impact-of-the-design
#2
Anne-Sophie Maisonneuve, Laetitia Huiart, Laetitia Rabayrol, Doug Horsman, Remi Didelot, Hagay Sobol, Francois Eisinger
BACKGROUND: Chemoprevention could significantly reduce cancer burden. Assessment of efficacy and risk/benefit balance is at best achieved through randomized clinical trials. METHODS: At a periodic health examination center 1463 adults were asked to complete a questionnaire about their willingness to be involved in different kinds of preventive clinical trials. RESULTS: Among the 851 respondents (58.2%), 228 (26.8%) agreed to participate in a hypothetical chemoprevention trial aimed at reducing the incidence of lung cancer and 116 (29...
2008: International Journal of Medical Sciences
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