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Growth preterm infants

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https://www.readbyqxmd.com/read/28822438/-effect-of-antenatal-corticosteroids-therapy-on-the-mortality-and-morbidity-of-small-for-gestational-age-infants-born-at-24-34-completed-weeks-a-retrospective-multicenter-study
#1
(no author information available yet)
Objective: To assess the impact of antenatal corticosteroids (ACS) therapy on mortality and morbidities in small for gestational age (SGA) preterm infants. Method: A retrospective database analysis was performed. Preterm infants born at 24-34 completed weeks who were diagnosed as SGA in 14 hospitals in China between 2013 and 2014 were evaluated for mortality and major morbidities including respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), intraventricular hemorrhage (IVH), necrotising enterocolitis (NEC), retinopathy of prematurity (ROP), patent ductus arteriosus (PDA) and sepsis...
August 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28806296/the-risk-of-necrotizing-enterocolitis-differs-among-preterm-pigs-fed-formulas-with-either-lactose-or-maltodextrin
#2
Randal K Buddington, Samantha L Davis, Karyl K Buddington
OBJECTIVES: When breast milk is unavailable for preterm infants, formulas are needed that won't increase the risk of necrotizing enterocolitis (NEC). Adding novel ingredients to formula to reduce NEC has not been effective clinically. Instead, we tested the prediction that NEC can be reduced by removing the maltodextrin now included in preterm formulas. METHODS: The preterm pig model of spontaneous NEC was used to evaluate growth, health, and intestinal responses to 6-7 days of feeding formulas that were identical except for the source of carbohydrate; either 100% lactose or maltodextrin; colostrum was used as the control...
August 11, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28798896/pregnancy-outcomes-in-hiv-infected-women-experience-from-a-tertiary-care-center-in-india
#3
Vatsla Dadhwal, Aparna Sharma, Kavita Khoiwal, Dipika Deka, Plaboni Sarkar, P Vanamail
BACKGROUND AND OBJECTIVES: There is conflicting data on the effect of HIV infection as well as antiretroviral therapy (ART) on pregnancy outcome. The objectives of this study were to compare pregnancy outcomes in women with and without HIV infection, and to evaluate the effect of HAART on pregnancy in HIV-infected women. METHODS: This is a prospective case record analysis of 212 HIV-infected women delivering between 2002 and 2015, in a tertiary health care center in India...
2017: International Journal of MCH and AIDS
https://www.readbyqxmd.com/read/28796908/maternal-and-infant-factors-had-a-significant-impact-on-birth-weight-and-longitudinal-growth-in-a-south-african-birth-cohort
#4
S Budree, D J Stein, K Brittain, E Goddard, N Koen, W Barnett, L Myer, H J Zar
AIM: This birth cohort study investigated longitudinal infant growth and associated factors in a multi-ethnic population living in a low-resource district surrounding the town of Paarl in South Africa. METHODS: Between March 2012 and October 2014, all mothers attending their second trimester antenatal visit at Paarl Hospital were approached for enrollment. Mother-infant pairs were followed from birth until 12 months of age. Comprehensive socio-demographic, nutritional and psychosocial data were collected at birth, two, six and 12 months...
August 10, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28780548/effect-of-single-family-rooms-for-preterm-infants-on-neurodevelopment-study-protocol-for-a-systematic-review
#5
Nicole R van Veenendaal, Sophie R D van der Schoor, Jacqueline Limpens, Anne A M W van Kempen, Johannes B van Goudoever
INTRODUCTION: Preterm infants are at an increased risk for neurodevelopmental delay. They have to endure many stressors in early life, including parent-infant separation, noise and painful procedures during hospitalisation in the highly technological environment of the modern neonatal ward. Currently, a shift is being noticed in the architectural design of neonatal wards towards single family rooms instead of the common open bay units. The influence of the hospital environment on health and specifically neurodevelopment in this vulnerable patient population remains under discussion...
August 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28777972/maternal-posttraumatic-stress-disorder-during-the-perinatal-period-and-child-outcomes-a-systematic-review
#6
REVIEW
Natalie Cook, Susan Ayers, Antje Horsch
BACKGROUND: Approximately 3.3% of women in pregnancy have posttraumatic stress disorder (PTSD) and 4% of women postpartum PTSD. The impact of maternal PTSD during the perinatal period (from conception until one year postpartum) on child outcomes has not been systematically examined. METHOD: A systematic review was conducted to synthesize and critically evaluate quantitative research investigating the association between perinatal PTSD and child outcomes. Databases EMBASE, BNI, Medline, PsycInfo and CINAHL were searched using specific inclusion and exclusion criteria...
July 27, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28777664/human-based-human-milk-fortifier-as-rescue-therapy-in-very-low-birth-weight-infants-demonstrating-intolerance-to-bovine-based-human-milk-fortifier
#7
Amanjot Sandhu, Sharla Fast, Kari Bonnar, Ronald John Baier, Michael Narvey
OBJECTIVE: To describe the results of utilizing a human milk-based human milk fortifier (HMHMF) as rescue therapy to meet nutritional requirements in very low birth weight and preterm infants demonstrating feeding intolerance to bovine-based human milk fortifier (BHMF) in the Canadian Neonatal Intensive Care Unit (NICU) setting. MATERIALS AND METHODS: At two Level III NICUs in Winnipeg, MB, Canada, a rescue protocol was implemented to provide HMHMF for infants demonstrating intolerance to BHMF...
August 4, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28777356/health-effects-of-carotenoids-during-pregnancy-and-lactation
#8
REVIEW
Monika A Zielińska, Aleksandra Wesołowska, Beata Pawlus, Jadwiga Hamułka
Adequate nutrition is particularly important during pregnancy since it is needed not only for maintaining the health of the mother, but also determines the course of pregnancy and its outcome, fetus development as well as the child's health after birth and during the later period of life. Data coming from epidemiological and interventions studies support the observation that carotenoids intake provide positive health effects in adults and the elderly population. These health effects are the result of their antioxidant and anti-inflammatory properties...
August 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28774357/-effect-of-extensively-hydrolyzed-formula-on-growth-and-development-of-infants-with-very-extremely-low-birth-weight
#9
Chun-Yan Gu, Hui-Fen Jiang, Jin-Xiu Wang
OBJECTIVE: To study the effect of extensively hydrolyzed formula on the growth and development in very low birth weight (VLBW) and extremely low birth weight (ELBW) infants. METHODS: A total of 375 VLBW or ELBW infants were enrolled and divided into an observation group (187 infants) and a control group (188 infants) using a random number table. The infants in the observation group were given extensively hydrolyzed formula, and when the amount of extensively hydrolyzed formula reached 10 mL/time, it was changed to the standard formula for preterm infants...
August 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28759409/head-growth-trajectory-and-neurodevelopmental-outcomes-in-preterm-neonates
#10
Kamini Raghuram, Junmin Yang, Paige T Church, Zenon Cieslak, Anne Synnes, Amit Mukerji, Prakesh S Shah
OBJECTIVES: To evaluate the association between head growth (HG) during neonatal and postdischarge periods and neurodevelopmental outcomes of preterm neonates of <29 weeks gestational age. METHODS: We conducted a retrospective cohort study of infants <29 weeks gestational
age admitted between 2009 and 2011 to participating Canadian Neonatal Network
units and followed by Canadian Neonatal Follow-Up Network clinics. Differences in head circumference (ΔHC) z score were calculated for 3 time periods, which include admission to discharge, discharge to follow-up at 16-36 months, and admission to follow-up...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28755859/systemic-inflammation-combined-with-neonatal-cerebellar-haemorrhage-aggravates-long-term-structural-and-functional-outcomes-in-a-mouse-model
#11
Sophie Tremblay, Alex Pai, Lindsay Richter, Rod Vafaei, Praneetha Potluri, Jacob Ellegood, Jason P Lerch, Daniel Goldowitz
BACKGROUND: Despite the increased recognition of cerebellar injury in survivors of preterm birth, the neurodevelopmental consequences of isolated cerebellar injury have been largely unexplored and our current understanding of the functional deficits requires further attention in order to translate knowledge to best practices. Preterm infants are exposed to multiple stressors during their postnatal development including perinatal cerebellar haemorrhage (CBH) and postnatal infection, two major risk factors for neurodevelopmental impairments...
July 27, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28749825/a-fortified-donor-milk-policy-is-associated-with-improved-in-hospital-head-growth-and-weight-gain-in-very-low-birth-weight-infants
#12
Gemma Ginovart, Ignasi Gich, Antonio Gutiérrez, Sergio Verd
BACKGROUND: Previous research has reported that infants fed donor milk grow slower than those fed formula. However, most of the trials used unfortified donor milk, which limits the ability to generalize the results to current clinical practice. PURPOSE: To evaluate the impact of early human milk feeding (donor milk and/or mother's own milk) with standard fortification on in-hospital growth of very low-birth-weight infants. METHODS: This pre-/postretrospective study included selected newborn infants less than 1500 g admitted to a level IV neonatal intensive care unit before and after the introduction of a policy providing donor milk when mother's own milk was not available in sufficient quantity to meet her infant's need...
August 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28737311/amniotic-band-syndrome-with-pseudoarthrosis-of-tibia-and-fibula-a-case-report
#13
A Ananthan, G Athalye Jape, J Du Plessis, P Annear, R Page, S Rao
Constriction of the lower limb by congenital amniotic band has been proposed to explain the development of pseudoarthrosis of tibia and fibula. We report a case of amniotic band syndrome in a preterm infant with pseudoarthrosis of tibia and fibula. Simple release of constriction band with Z-plasty resulted in the growth of mature bone, replacing the pseudoarthrosis and hence did not require surgical amputation. Our case confirms the potential for bone growth in ABS, once the constricting band is released. Early limb preserving surgery with release of the constricting band with an intention to salvage the limb appears appropriate...
May 10, 2017: Irish Medical Journal
https://www.readbyqxmd.com/read/28733478/growth-and-morbidity-of-extremely-preterm-infants-after-early-full-enteral-nutrition
#14
Christoph Maas, Axel R Franz, Stefanie von Krogh, Jörg Arand, Christian F Poets
OBJECTIVES: To evaluate feasibility and consequences of accelerated feeding advancement on short-term outcomes in extremely low gestational age neonates (ELGANs) who stayed in our institution for >28 days. METHODS: Retrospective single-centre cohort analysis covering the years 2011-2013. Data are presented as median (IQR). RESULTS: Infants '(n=77) birth weight was 745 (640 to 960) g and gestational age at birth 26.7 (25.1 to 27.4) weeks...
July 21, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28729313/fetal-doppler-velocimetry-and-bronchopulmonary-dysplasia-risk-among-growth-restricted-preterm-infants-an-observational-study
#15
Alessandra Lio, Paolo Rosati, Roberta Pastorino, Francesco Cota, Milena Tana, Chiara Tirone, Claudia Aurilia, Cinzia Ricci, Alessandro Gambacorta, Angela Paladini, Ilenia Mappa, Silvia Buongiorno, Gian Franco Zannoni, Costantino Romagnoli, Giovanni Vento
OBJECTIVE: To investigate whether fetal growth restriction (FGR) diagnosis, based on pathological prenatal fetal Doppler velocimetry, is associated with bronchopulmonary dysplasia (BPD) independently of being small for gestational age (SGA) per se at birth among very preterm infants. DESIGN: Prospective, observational study. FGR was defined as failing fetal growth in utero and fetal Doppler velocimetry abnormalities. SETTING: Policlinico Universitario Agostino Gemelli, Roma, Italy...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28727654/growth-and-nutritional-biomarkers-of-preterm-infants-fed-a-new-powdered-human-milk-fortifier-a-randomized-trial
#16
Jacques Rigo, Jean-Michel Hascoët, Claude Billeaud, Jean-Charles Picaud, Fabio Mosca, Amandine Rubio, Elie Saliba, Michaël Radkë, Umberto Simeoni, Bernard Guillois, Virginie de Halleux, Jonathan Jaeger, Laurent Ameye, Nicholas P Hays, Johannes Spalinger
OBJECTIVES: Assess growth and nutritional biomarkers of preterm infants fed human milk (HM) supplemented with a new powdered HM fortifier (nHMF) or a control HM fortifier (cHMF). The nHMF provides similar energy content, 16% more protein (partially hydrolyzed whey), and higher micronutrient levels than the cHMF, along with medium-chain triglycerides and docosahexaenoic acid. METHODS: In this controlled, multicenter, double-blind study, a sample of preterm infants ≤32 weeks or ≤1500 g were randomized to receive nHMF (n = 77) or cHMF (n = 76) for a minimum of 21 days...
July 19, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28718213/safety-and-dose-finding-trial-of-tadalafil-administered-for-fetal-growth-restriction-a-phase-1-clinical-study
#17
Michiko Kubo, Hiroaki Tanaka, Shintaro Maki, Masafumi Nii, Nao Murabayashi, Kazuhiro Osato, Yuki Kamimoto, Takashi Umekawa, Eiji Kondo, Tomoaki Ikeda
AIM: We designed a safety and dose-finding trial of tadalafil administered for fetal growth restriction (FGR). METHODS: Three cases were initially commenced on 10 mg/day and monitored for major adverse events. Should a major adverse event be observed in one or more of the three cases, an examination into its relation with tadalafil would be conducted by a safety evaluation committee. If one or more of these new cases exhibited the same adverse event, the trial would be stopped completely...
July 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28711069/preterm-birth-and-its-impact-on-renal-health
#18
Valerie A Luyckx
Preterm birth occurs in approximately 10% of all births worldwide. Preterm infants have reduced nephron numbers at birth in proportion to gestational age, and are at increased risk of neonatal acute kidney injury as well as higher blood pressure, proteinuria, and chronic kidney disease later in life. Rapid catch-up growth in preterm infants, especially if resulting in obesity, is a risk factor for end-stage kidney disease among children with proteinuric renal disease. Preterm birth, however, is a risk factor not only for the infant because mothers who deliver preterm have an increased risk of having subsequent preterm deliveries as well as hypertension, cardiovascular disease, and renal disease later in life...
July 2017: Seminars in Nephrology
https://www.readbyqxmd.com/read/28701177/longitudinal-development-of-the-gut-microbiome-and-metabolome-in-preterm-neonates-with-late-onset-sepsis-and-healthy-controls
#19
Christopher J Stewart, Nicholas D Embleton, Emma C L Marrs, Daniel P Smith, Tatiana Fofanova, Andrew Nelson, Tom Skeath, John D Perry, Joseph F Petrosino, Janet E Berrington, Stephen P Cummings
BACKGROUND: Late onset sepsis (LOS) in preterm infants is associated with considerable morbidity and mortality. While studies have implicated gut bacteria in the aetiology of the disease, functional analysis and mechanistic insights are generally lacking. We performed temporal bacterial (n = 613) and metabolomic (n = 63) profiling on extensively sampled stool from 7 infants with LOS and 28 matched healthy (no LOS or NEC) controls. RESULTS: The bacteria isolated in diagnostic blood culture usually corresponded to the dominant bacterial genera in the gut microbiome...
July 12, 2017: Microbiome
https://www.readbyqxmd.com/read/28699095/maternal-education-gradients-in-infant-health-in-four-south-american-countries
#20
George L Wehby, Jorge S López-Camelo
Objective We investigate gradients (i.e. differences) in infant health outcomes by maternal education in Argentina, Brazil, Chile, and Venezuela and explore channels related to father's education, household labor outcomes, and maternal health, fertility, and use of prenatal services and technology. Methods We employ secondary interview and birth record data similarly collected across a network of birth hospitals from the early 1980s through 2011 within the Latin American Collaborative Study of Congenital Anomalies (ECLAMC)...
July 11, 2017: Maternal and Child Health Journal
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