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Growth preterm infants

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https://www.readbyqxmd.com/read/29035757/pulmonary-hypertension-associated-with-bronchopulmonary-dysplasia-in-preterm-infants
#1
REVIEW
Christine B Bui, Merrin A Pang, Arvind Sehgal, Christiane Theda, Jason C Lao, Philip J Berger, Marcel F Nold, Claudia A Nold-Petry
Bronchopulmonary dysplasia (BPD) and BPD-associated pulmonary hypertension (BPD-PH) are chronic inflammatory cardiopulmonary diseases with devastating short- and long-term consequences for infants born prematurely. The immature lungs of preterm infants are ill-prepared to achieve sufficient gas exchange, thus usually necessitating immediate commencement of respiratory support and oxygen supplementation. These therapies are life-saving, but they exacerbate the tissue damage that is inevitably inflicted on a preterm lung forced to perform gas exchange...
October 2, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29031041/concept-analysis-of-growth-failure-in-preterm-infants-in-the-nicu
#2
Lindsay K Schehr, Teresa S Johnson
Growth failure has not been consistently defined for preterm infants, which contributes to unclear clinical guidelines for optimal growth and development. Therefore, the purpose of this concept analysis was to identify all uses and attributes of the concept, present model and contrary cases, identify antecedents and consequences, define empirical referents, and provide an operational definition of growth failure among preterm infants in the NICU.
October 11, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/29030727/-parenteral-nutrition-in-premature-babies-with-a-birth-weight-1500g-a%C3%A2-systematic-single-center-analysis-and-comparison-with-current-guidelines
#3
Melanie Sirch, Martin Poryo, Mona Butte, Ulrike Lindner, Ludwig Gortner, Michael Zemlin, Holger Nunold, Sascha Meyer
BACKGROUND: Parenteral and enteral nutrition are essential for both growth and development of preterm infants. Based on the results of many studies, the rate of nutritional growth and the amount of substrate delivered parenterally are under debate. OBJECTIVE: The main aim of this study was to assess parenteral nutrition in very and extremely immature preterm infants, i.e. very low birth weight (VLBW, birth weight <1500g) and extremely low birth weight (ELBW, birth weight <1000g) neonates, and to compare the amount of parenterally delivered substrate in our neonatal intensive care unit (NICU) to current German guidelines...
October 13, 2017: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29027762/fresh-noncultured-endothelial-progenitor-cells-improve-neonatal-lung-hyperoxia-induced-alveolar-injury
#4
Alexandra B Firsova, A Daniel Bird, Degu Abebe, Judy Ng, Richard Mollard, Timothy J Cole
Treatment of preterm human infants with high oxygen can result in disrupted lung alveolar and vascular development. Local or systemic administration of endothelial progenitor cells (EPCs) is reported to remedy such disruption in animal models. In this study, the effects of both fresh (enriched for KDR) and cultured bone marrow (BM)-derived cell populations with EPC characteristics were examined following hyperoxia in neonatal mouse lungs. Intraperitoneal injection of fresh EPCs into five-day-old mice treated with 90% oxygen resulted in full recovery of hyperoxia-induced alveolar disruption by 56 days of age...
October 13, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29025726/gestational-age-at-birth-and-brain-white-matter-development-in-term-born-infants-and-children
#5
X Ou, C M Glasier, R H Ramakrishnaiah, A Kanfi, A C Rowell, R T Pivik, A Andres, M A Cleves, T M Badger
BACKGROUND AND PURPOSE: Studies on infants and children born preterm have shown that adequate gestational length is critical for brain white matter development. Less is known regarding how variations in gestational age at birth in term infants and children affect white matter development, which was evaluated in this study. MATERIALS AND METHODS: Using DTI tract-based spatial statistics methods, we evaluated white matter microstructures in 2 groups of term-born (≥37 weeks of gestation) healthy subjects: 2-week-old infants (n = 44) and 8-year-old children (n = 63)...
October 12, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29019853/holder-pasteurized-human-donor-milk-how-long-can-it-be-preserved
#6
Marita de Waard, Elise Mank, Karin van Dijk, Anne Schoonderwoerd, Johannes B van Goudoever
OBJECTIVE: When own mother's milk falls short, pasteurized human donor milk is recommended as alternative feeding for preterm infants. Donor milk has to meet the highest safety standards, but its processing and storage is expensive. The recommended storage time of pasteurized donor milk is three months. The objective of this study was to determine if the frozen storage time of pasteurized donor milk can be extended beyond 3 months without compromising its safety and quality. METHODS: For this prospective observational study breast-milk samples of 34 unique women, collected between November 2014 and June 2015, were provided by the Dutch Human Milk Bank...
October 10, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29016653/randomized-trial-of-two-doses-of-vitamin-d3-in-preterm-infants-32-weeks-dose-impact-on-achieving-desired-serum-25-oh-d3-in-a-nicu-population
#7
Ann Anderson-Berry, Melissa Thoene, Julie Wagner, Elizabeth Lyden, Glenville Jones, Martin Kaufmann, Matthew Van Ormer, Corrine Hanson
BACKGROUND: Recommendations for vitamin D supplementation for preterm infants span a wide range of doses. Response to vitamin D supplementation and impact on outcomes in preterm infants is not well understood. OBJECTIVE: Evaluate serum 25(OH)D3 concentration changes after 4 weeks in response to two different doses of vitamin D3 supplementation in a population of premature infants and quantify the impact on NICU outcomes. DESIGN: 32 infants born at 24-32 weeks gestation were prospectively randomized to receive 400 or 800 IU/day vitamin D3 supplementation...
2017: PloS One
https://www.readbyqxmd.com/read/28993767/genomic-programming-of-human-neonatal-dendritic-cells-in-congenital-systemic-and-in-vitro-cytomegalovirus-infection-reveal-plastic-and-robust-immune-pathway-biology-responses
#8
Widad Dantoft, Pablo Martínez-Vicente, James Jafali, Lara Pérez-Martínez, Kim Martin, Konstantinos Kotzamanis, Marie Craigon, Manfred Auer, Neil T Young, Paul Walsh, Arnaud Marchant, Ana Angulo, Thorsten Forster, Peter Ghazal
Neonates and especially premature infants are highly susceptible to infection but still can have a remarkable resilience that is poorly understood. The view that neonates have an incomplete or deficient immune system is changing. Human neonatal studies are challenging, and elucidating host protective responses and underlying cognate pathway biology, in the context of viral infection in early life, remains to be fully explored. In both resource rich and poor settings, human cytomegalovirus (HCMV) is the most common cause of congenital infection...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28975028/participatory-design-methods-for-the-development-of-a-clinical-telehealth-service-for-neonatal-homecare
#9
Kristina Garne Holm, Anne Brødsgaard, Gitte Zachariassen, Anthony C Smith, Jane Clemensen
OBJECTIVES: Neonatal homecare delivered during home visits by neonatal nurses is a common method for supporting families of preterm infants following discharge. Telehealth has been introduced for the provision of neonatal homecare, resulting in positive feedback from parents of preterm infants. While the benefits are beginning to be realised, widespread uptake of telehealth has been limited due to a range of logistical challenges. Understanding user requirements is important when planning and developing a clinical telehealth service...
2017: SAGE Open Medicine
https://www.readbyqxmd.com/read/28972955/impaired-cerebellar-maturation-growth-restriction-and-circulating-insulin-like-growth-factor-1-in-preterm-rabbit-pups
#10
Kristbjörg Sveinsdóttir, John-Kalle Länsberg, Snjólaug Sveinsdóttir, Martin Garwicz, Lennart Ohlsson, Ann Hellström, Lois Smith, Magnus Gram, David Ley
Cerebellar growth is impeded following very preterm birth in human infants and the observed reduction in cerebellar volume is associated with neurodevelopmental impairment. Decreased levels of circulating insulin-like growth factor 1 (IGF-1) are associated with decreased cerebellar volume. The relationship between preterm birth, circulating IGF-1, and key cell populations supporting cerebellar proliferation is unknown. The aim of this study was to evaluate the effect of preterm birth on postnatal growth, circulating IGF-1, and cerebellar maturation in a preterm rabbit pup model...
October 4, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28969546/igf-1-as-a-drug-for-preterm-infants-a-step-wise-clinical-development
#11
Ann Hellstrom, David Ley, Boubou Hallberg, Chatarina Lofqvist, Ingrid Hansen-Pupp, Luca A Ramenghi, Jan Borg, Lois E H Smith, Anna-Lena Hard
BACKGROUND: Insulin-like growth factor 1 (IGF-1) is a mitogenic hormone involved in many processes such as growth, metabolism, angiogenesis and differentiation. After very preterm birth, energy demands increase while maternal supplies of nutrients and other factors are lost and the infant may become dependent on parenteral nutrition for weeks. Low postnatal IGF-1 concentrations in preterm infants are associated with poor weight gain, retinopathy of prematurity (ROP) and other morbidities...
October 2, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28968486/protein-hydrolysate-versus-standard-formula-for-preterm-infants
#12
REVIEW
Derek Hang Cheong Ng, Joel Klassen, Nicholas D Embleton, William McGuire
BACKGROUND: When human milk is not available for feeding preterm infants, protein hydrolysate rather than standard cow's milk formulas (with intact proteins) are often used because they are perceived as being tolerated better and less likely to lead to complications. However, protein hydrolysate formulas are more expensive than standard formulas, and concern exists that their use in practice is not supported by high-quality evidence. OBJECTIVES: To assess the effect of feeding preterm infants with hydrolysed formula (versus standard cow's milk formulas) on the risk of feed intolerance, necrotising enterocolitis, and other morbidity and mortality in preterm infants...
October 2, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28958983/the-association-between-maternal-subclinical-hypothyroidism-and-growth-development-and-childhood-intelligence-a-meta-analysis
#13
Yahong Liu, Hui Chen, Jing Chen, Fupin Li
OBJECTIVES: To explore the association between maternal subclinical hypothyroidism (SCH) in pregnancy and the development of their children. METHODS: Using RevMan 5.3 software, we performed a meta-analysis of cohort studies published from inception to May 2017, focusing on the association between maternal SCH in pregnancy and childhood growth, development and intelligence. Sources included the Cochrane Library, Pub-Med, Web of Science, CNKI, and Wan Fang Data. RESULTS: We included a total of 15 cohort studies involving 1,896 pregnant women with SCH...
September 29, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28957424/nutrition-after-preterm-birth-and-adult-neurocognitive-outcomes
#14
Sara Sammallahti, Eero Kajantie, Hanna-Maria Matinolli, Riikka Pyhälä, Jari Lahti, Kati Heinonen, Marius Lahti, Anu-Katriina Pesonen, Johan G Eriksson, Petteri Hovi, Anna-Liisa Järvenpää, Sture Andersson, Katri Raikkonen
BACKGROUND: Preterm birth (<37 gestational weeks) poses a risk of poorer neurocognitive functioning. Faster growth after preterm birth predicts better cognitive abilities and can be promoted through adequate nutrition, but it remains unknown whether variations in nutrient intakes translate into long-term benefits for neurodevelopment. METHODS: In 86 participants of the Helsinki Study of Very Low Birth Weight Adults (birthweight <1500g), we examined if higher intakes of energy, macronutrients, and human milk during the first nine weeks after preterm birth predict performance in tests of cognitive ability at 25...
2017: PloS One
https://www.readbyqxmd.com/read/28954564/maternal-and-neonatal-outcomes-among-pregnant-women-with-fibromyalgia-a-population-based-study-of-12-million-births
#15
Glenda Gatan Magtanong, Andrea R Spence, Nicholas Czuzoj-Shulman, Haim Arie Abenhaim
PURPOSE: Fibromyalgia (FM) is a rheumatologic disorder marked by chronic, widespread pain and associated comorbid conditions. The purpose of our study was to evaluate the effect of FM on maternal and neonatal outcomes. METHODS: Using the Healthcare Cost and Utilization Project Nationwide Inpatient Sample from 1999 to 2013, we conducted a population-based retrospective cohort study consisting of women who delivered during that period. Logistic regression was used to compare maternal and neonatal outcomes among pregnancies in women with and without FM...
September 27, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28953531/association-of-heparin-binding-egf-like-growth-factor-polymorphisms-with-necrotizing-enterocolitis-in-preterm-infants
#16
Fei Ma, Sitao Li, Hu Hao, Pingmin Gao, Yiheng Dai, Chhetri Himani, Weidong Liu, Xiaoyan Gao, Xin Xiao
Heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) protects the intestines from injury in experimental necrotizing enterocolitis (NEC). We hypothesized that polymorphisms in the HB-EGF gene lead to low HB-EGF production in peripheral blood and increased risk of NEC in the Chinese Han population. To test this hypothesis, thirty NEC patients and eighty control subjects were selected. Five HB-EGF single-nucleotide polymorphisms (SNPs) and its plasma levels were measured by genotyping and ELISA, respectively...
September 26, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28953525/nutrition-practices-and-predictors-of-postnatal-growth-in-preterm-infants-during-hospitalization-a-longitudinal-study
#17
Briar L McKenzie, Liza Edmonds, Ruth Thomson, Jillian J Haszard, Lisa A Houghton
Premature infants are at high risk of undernutrition and extrauterine growth restriction (EUGR). AIM: To evaluate the relation between nutrition practices and growth rate in preterm infants from birth to 36 weeks postmenstrual age (PMA). METHODS: Longitudinal data were collected retrospectively in 103 infants born <33-weeks gestation admitted to Dunedin NICU, New Zealand. Weight, length and head circumference at birth and 36-weeks PMA z-scores were calculated using the INTERGROWTH Preterm Growth Standard...
September 26, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28952458/sialic-acid-and-iron-contents-in-breast-milk-of-chinese-lactating-women
#18
Hong-Jiao Wang, Chun-Zhen Hua, Li-Li Ruan Hebbal, Li-Quan Hong Aguiar, Shao-Qin Sheng, Shi-Qiang Shang
OBJECTIVE: To study sialic acid and iron content in breast milk in Chinese women during different lactation stages. METHODS: Sialic acid and iron content of colostrum, transitional milk, mature milk, and involutional milk were determined using a neuraminidase assay kit and the ferrozine method, respectively in 88 lactating women (58 Term, 30 Preterm). RESULTS: The mean (SD) sialic acid levels of colostrum, transitional milk, mature milk, and involutional milk were 2201...
September 26, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28947670/maternal-ambient-air-pollution-preterm-birth-and-markers-of-fetal-growth-in-rhode-island-results-of-a-hospital-based-linkage-study
#19
Samantha L Kingsley, Melissa N Eliot, Kimberly Glazer, Yara Abu Awad, Joel D Schwartz, David A Savitz, Karl T Kelsey, Carmen J Marsit, Gregory A Wellenius
BACKGROUND: Maternal exposure to ambient air pollution has been associated with higher risk of preterm birth and reduced fetal growth, but heterogeneity among prior studies suggests that additional studies are needed in diverse populations and settings. We examined the associations between maternal ambient air pollution levels, risk of preterm birth and markers of fetal growth in an urban population with relatively low exposure to air pollution. METHODS: We linked 61 640 mother-infant pairs who delivered at a single hospital in Providence, Rhode Island, from 2002 to 2012 to birth certificate and hospital discharge data...
September 25, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28937236/impact-of-early-aggressive-nutrition-on-retinal-development-in-premature-infants
#20
N Lenhartova, K Matasova, Z Lasabova, K Javorka, A Calkovska
The normal retinal development is interrupted by preterm birth and a retinopathy of prematurity (ROP) may develop as its consequence. ROP is characterized by aberrant vessel formation in the retina as a response to multiple risk factors influencing the process of retinal angiogenesis. Insulin-like growth factor I (IGF-1) and vascular endothelial growth factor (VEGF) play an important role in the process of normal retinal vascularization. Insufficient nutrition during the first 4 postnatal weeks results in low serum levels of IGF-1, which is essential for correct retinal vessels formation, ensuring survival of the newly formed endothelial cells...
September 22, 2017: Physiological Research
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