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Growth preterm infants

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https://www.readbyqxmd.com/read/29228972/impact-of-prematurity-and-nutrition-on-the-developing-gut-microbiome-and-preterm-infant-growth
#1
Alex Grier, Xing Qiu, Sanjukta Bandyopadhyay, Jeanne Holden-Wiltse, Haeja A Kessler, Ann L Gill, Brooke Hamilton, Heidie Huyck, Sara Misra, Thomas J Mariani, Rita M Ryan, Lori Scholer, Kristin M Scheible, Yi-Horng Lee, Mary T Caserta, Gloria S Pryhuber, Steven R Gill
BACKGROUND: Identification of factors that influence the neonatal gut microbiome is urgently needed to guide clinical practices that support growth of healthy preterm infants. Here, we examined the influence of nutrition and common practices on the gut microbiota and growth in a cohort of preterm infants. RESULTS: With weekly gut microbiota samples spanning postmenstrual age (PMA) 24 to 46 weeks, we developed two models to test associations between the microbiota, nutrition and growth: a categorical model with three successive microbiota phases (P1, P2, and P3) and a model with two periods (early and late PMA) defined by microbiota composition and PMA, respectively...
December 11, 2017: Microbiome
https://www.readbyqxmd.com/read/29217722/successfully-implementing-and-embedding-guidelines-to-improve-the-nutrition-and-growth-of-preterm-infants-in-neonatal-intensive-care-a-prospective-interventional-study
#2
Mark J Johnson, Alison A Leaf, Freya Pearson, Howard W Clark, Borislav D Dimitrov, Catherine Pope, Carl R May
OBJECTIVES: We aimed to improve the nutritional care of preterm infants by developing a complex (multifaceted) intervention intended to translate current evidence into practice. We used the sociological framework of Normalization Process Theory (NPT), to guide implementation in order to embed the new practices into routine care. DESIGN: A prospective interventional study with a before and after methodology. PARTICIPANTS: Infants <30 weeks gestation or <1500 g at birth...
December 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/29212397/growth-and-neurodevelopment-in-very-preterm-infants-receiving-a-high-enteral-volume-feeding-regimen-a-population-based-cohort-study
#3
Claus Klingenberg, Fredrik Kragh Muraas, Catherine Elde Isaksen, Tina Nilsen, Marte Torgersen, Cecilie Melum-Hansen
AIM: To evaluate a feeding regimen routinely providing > 180 ml/kg/d fortified human milk to very preterm infants and impact on in-hospital growth, osteopenia and neurodevelopment. METHOD: Retrospective population-based descriptive study of infants < 30-week gestation admitted within 24 h of birth and discharged during the 6-year period 2005 to 2010. Growth and neurodevelopment was assessed until 2 years corrected age, and cerebral palsy up to 4 years corrected age Results: Ninety-nine infants below 30-week gestation were admitted within 24 h of birth during the 6-year period, of which 84 (85%) survived to discharge...
December 6, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29210994/iron-supplementation-during-pregnancy-and-infancy-uncertainties-and-implications-for-research-and-policy
#4
REVIEW
Patsy M Brannon, Christine L Taylor
Iron is particularly important in pregnancy and infancy to meet the high demands for hematopoiesis, growth and development. Much attention has been given to conditions of iron deficiency (ID) and iron deficient anemia (IDA) because of the high global prevalence estimated in these vulnerable life stages. Emerging and preliminary evidence demonstrates, however, a U-shaped risk at both low and high iron status for birth and infant adverse health outcomes including growth, preterm birth, gestational diabetes, gastrointestinal health, and neurodegenerative diseases during aging...
December 6, 2017: Nutrients
https://www.readbyqxmd.com/read/29209598/inflammatory-mediators-in-tracheal-aspirates-of-preterm-infants-participating-in-a-randomized-trial-of-permissive-hypercapnia
#5
Sarah Gentner, Mandy Laube, Ulrike Uhlig, Yang Yang, Hans W Fuchs, Jens Dreyhaupt, Helmut D Hummler, Stefan Uhlig, Ulrich H Thome
Background: Ventilator-induced lung injury is considered to be a main factor in the pathogenesis of bronchopulmonary dysplasia (BPD). Optimizing ventilator strategies may reduce respiratory morbidities in preterm infants. Permissive hypercapnia has been suggested to attenuate lung injury. We aimed to determine if a higher PCO2 target range results in less lung injury compared to the control target range and possibly reduces pro-inflammatory cytokines and acid sphingomyelinase (ASM) in tracheal aspirates (TA), which has not been addressed before...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29207479/growth-and-bone-mineralization-of-very-preterm-infants-at-term-corrected-age-in-relation-to-different-nutritional-intakes-in-the-early-postnatal-period
#6
Michelle N Körnmann, Viola Christmann, Charlotte J W Gradussen, Laura Rodwell, Martin Gotthardt, Johannes B Van Goudoever, Arno F J Van Heijst
Preterm infants often have a reduced bone mineral content (BMC) with increased risk of metabolic bone disease. After birth it is difficult to supply calcium (Ca) and phosphorus (P) comparable to the high fetal accretion rate. It is not known whether high supplementation of minerals in the early postnatal period improves growth and bone mineralization. The aim of this study was to evaluate growth and bone mineralization at term corrected age (TCA) in very and extremely preterm infants who received different enteral Ca and P intakes during the first 10 days of life...
December 2, 2017: Nutrients
https://www.readbyqxmd.com/read/29205630/health-care-professionals-approach-in-feeding-term-small-for-gestational-age-infants-and-its-potential-implications-to-later-growth-outcomes
#7
Le Ye Lee, Leilani Muhardi, Fook-Choe Cheah, Sarayut Supapannachart, Inga C Teller, Jacques Bindels, Eline M van Der Beek, Ruurd M van Elburg
AIM: To understand feeding practices, nutrition management and postnatal growth monitoring of term small-for-gestational age (tSGA) infants in Southeast Asia. METHODS: Anonymous questionnaires to assess practices on feeding, nutrition management and post-natal growth monitoring of tSGA infants were distributed among health-care professionals (HCPs) participating in regional/local perinatology symposia in Malaysia, Thailand and Singapore. RESULTS: Three hundred seventy-seven respondents from Malaysia (37%), Thailand (27%), Singapore (18%) and other Asian countries (19%) participated in the survey...
December 5, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29200180/procedural-pain-and-oral-glucose-in-preterm-neonates-brain-development-and-sex-specific-effects
#8
Juliane Schneider, Emma G Duerden, Ting Guo, Karin Ng, Patric Hagmann, Myriam Bickle Graz, Ruth E Grunau, M Mallar Chakravarty, Petra S Hüppi, Anita C Truttmann, Steven P Miller
Our objectives were to determine whether procedural pain and glucose exposure are associated with altered structural and functional brain development differently in preterm males and females, and neurodevelopment at 18-months corrected age. Fifty-one very-preterm neonates (22 males; median[IQR] gestational age 27.6[2.0] weeks) underwent three serial scans including T1-weighted and resting-state functional magnetic resonance imaging (MRI) at median postmenstrual weeks: 29.4, 31.9, and 41.1. Thalamus, basal ganglia, and total brain volumes were segmented...
December 1, 2017: Pain
https://www.readbyqxmd.com/read/29199029/the-effect-of-customization-and-use-of-a-fetal-growth-standard-on-the-association-between-birthweight-percentile%C3%A2-and-adverse-perinatal-outcome
#9
Ulla Sovio, Gordon C S Smith
BACKGROUND: It has been proposed that correction of offspring weight percentiles (customization) might improve the prediction of adverse pregnancy outcome; however, the approach is not accepted universally. A complication in the interpretation of the data is that the main method for calculation of customized percentiles uses a fetal growth standard, and multiple analyses have compared the results with birthweight-based standards. OBJECTIVES: First, we aimed to determine whether women who deliver small-for-gestational-age infants using a customized standard differed from other women...
December 1, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29198539/long-term-outcomes-of-hyperglycemic-preterm-infants-randomized-to-tight-glycemic-control
#10
Anna Catherine Tottman, Jane Marie Alsweiler, Frank Harry Bloomfield, Greg Gamble, Yannan Jiang, Myra Leung, Tanya Poppe, Benjamin Thompson, Trecia Ann Wouldes, Jane Elizabeth Harding
OBJECTIVE: To determine whether tight glycemic control of neonatal hyperglycemia changes neurodevelopment, growth, and metabolism at school age. STUDY DESIGN: Children born very low birth weight and randomized as hyperglycemic neonates to a trial of tight vs standard glycemic control were assessed at 7 years corrected age, including Wechsler Intelligence Scale for Children Fourth Edition, Movement Assessment Battery for Children 2, visual and neurologic examinations, growth measures, dual X-ray absorptiometry, and frequently sampled intravenous glucose tolerance test...
November 30, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29198223/ibuprofen-and-indomethacin-differentially-regulate-vascular-endothelial-growth-factor-and-its-receptors-in-ductus-arteriosus-endothelial-cells
#11
Hannes Sallmon, Sandra Akanbi, Sven C Weber, Alexander Gratopp, Cornelia Rheinländer, Petra Koehne
BACKGROUND: Cyclooxygenase inhibitors are widely applied to facilitate ductal closure in preterm infants. The mechanisms that lead to patent ductus arteriosus closure are incompletely understood. Vascular endothelial growth factor plays pivotal roles during ductal closure and remodelling. Aim The aim of this study was to investigate the effects of ibuprofen and indomethacin on the expression of vascular endothelial growth factor and its receptors in a primary rat ductus arteriosus endothelial cell culture...
December 4, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29187358/vitamin-d-supplementation-during-pregnancy-state-of-the-evidence-from-a-systematic-review-of-randomised-trials
#12
Daniel E Roth, Michael Leung, Elnathan Mesfin, Huma Qamar, Jessica Watterworth, Eszter Papp
Objectives To estimate the effects of vitamin D supplementation during pregnancy on 11 maternal and 27 neonatal/infant outcomes; to determine frequencies at which trial outcome data were missing, unreported, or inconsistently reported; and to project the potential contributions of registered ongoing or planned trials.Design Systematic review and meta-analysis of randomised controlled trials; systematic review of registered but unpublished trials.Data sources Medline, Embase, PubMed, Cochrane Database of Systematic Reviews, and Cochrane Central Register of Controlled Trials from inception to September 2017; manual searches of reference lists of systematic reviews identified in the electronic search; and online trial registries for unpublished, ongoing, or planned trials...
November 29, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29186903/bacteriological-and-immunological-profiling-of-meconium-and-fecal-samples-from-preterm-infants-a-two-year-follow-up-study
#13
Marta Gómez, Laura Moles, Irene Espinosa-Martos, Gerardo Bustos, Willem M de Vos, Leónides Fernández, Juan M Rodríguez, Susana Fuentes, Esther Jiménez
An abnormal colonization pattern of the preterm gut may affect immune maturation and exert a long-term influence on the intestinal bacterial composition and host health. However, follow-up studies assessing the evolution of the fecal microbiota of infants that were born preterm are very scarce. In this work, the bacterial compositions of fecal samples, obtained from sixteen 2-year-old infants were evaluated using a phylogenetic microarray; subsequently, the results were compared with those obtained in a previous study from samples of meconium and feces collected from the same infants while they stayed in the neonatal intensive care unit (NICU)...
November 27, 2017: Nutrients
https://www.readbyqxmd.com/read/29186804/neonatal-nutrition-predicts-energy-balance-in-young-adults-born-preterm-at-very-low-birth-weight
#14
(no author information available yet)
Epidemiological studies and animal models suggest that early postnatal nutrition and growth can influence adult health. However, few human studies have objective recordings of early nutrient intake. We studied whether nutrient intake and growth during the first 9 weeks after preterm birth with very low birth weight (VLBW, <1500 g) predict total energy intake, resting energy expenditure (REE), physical activity and food preferences in young adulthood. We collected daily nutritional intakes and weights during the initial hospital stay from hospital records for 127 unimpaired VLBW participants...
November 24, 2017: Nutrients
https://www.readbyqxmd.com/read/29186633/family-centered-care-improved-neonatal-medical-and-neurobehavioral-outcomes-in-preterm-infants-randomized-controlled-trial
#15
Yen-Ting Yu, Wu-Shiun Hsieh, Chyong-Hsin Hsu, Yuh-Jyh Lin, Chyi-Her Lin, Shulan Hsieh, Lu Lu, Rong-Ju Cherng, Ying-Ju Chang, Pi-Chuan Fan, Nai-Jia Yao, Wei J Chen, Suh-Fang Jeng
Background: Family-centered care for preterm infants in Western societies has yielded short- to medium-term benefits. However, the intervention effects have rarely been validated in Eastern societies. Objective: The aim of this study was to examine whether a family-centered intervention program (FCIP) could improve the short-term medical and neurobehavioral outcomes in preterm infants with very low birth weight (VLBW; a birth weight of <1,500 g) in Taiwan over the outcomes seen with a usual care program (UCP)...
December 1, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29184814/hypoglycemia-in-the-preterm-neonate-etiopathogenesis-diagnosis-management-and-long-term-outcomes
#16
REVIEW
Anudeepa Sharma, Ajuah Davis, Prem S Shekhawat
Glucose, like oxygen, is of fundamental importance for any living being and it is the major energy source for the fetus and the neonate during gestation. The placenta ensures a steady supply of glucose to the fetus, while birth marks a sudden change in substrate delivery and a major change in metabolism. Hypoglycemia is one of the most common pathologies encountered in the neonatal intensive care unit and affects a wide range of neonates. Preterm, small for gestational age (GA) and intra-uterine growth restricted neonates are especially vulnerable due to their lack of metabolic reserves and associated co-morbidities...
October 2017: Translational Pediatrics
https://www.readbyqxmd.com/read/29183092/-methamphetamine-consumption-during-pregnancy-and-its-effects-on-neonates
#17
Alina Pflügner, Ulrich Thome, Matthias K Bernhard, Mandy Vogel, Annett Bläser, Petra Nickel, Wieland Kiess
Objective Methamphetamine (MA) has become one of the most commonly used illegal drugs during pregnancy. We sought to determine how MA abuse modifies pregnancy outcomes and the health of the newborn infants. Patients 102 newborns from mothers with antenatal MA consumption were admitted to the University Hospital Leipzig from 2004-2015. Methods The effects of MA abuse on pregnancy outcomes and neonates were researched in a retrospective controlled study. We analysed the date of pregnancy detection, number of antenatal preventive examinations, body measurements of the neonates, duration of hospitalization, rate of preterm infants, congenital malformations and symptoms of neonatal abstinence syndrome...
November 28, 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/29181690/association-of-maternal-depression-with-dietary-intake-growth-and-development-of-preterm-infants-a-cohort-study-in-beijing-china
#18
Han Wang, Hong Zhou, Yan Zhang, Yan Wang, Jing Sun
This study aimed to explore the association of maternal depression with nutrient intake, growth, and development of preterm infants. A cohort study of 201 infants was conducted in Beijing. Based on the gestational age of an infant and status of the mother, the infants were divided into four groups: non-depression-fullterm (64), non-depression-preterm (70), depression-fullterm (36), and depression-preterm (31). Data on sociodemographic characteristics, nutritional intake, growth, and developmental status of children at 8 months (corrected ages) were collected using a quantitative questionnaire, a 24-Hour Dietary Recall, anthropometric measurements, and the Bayley-III scale...
November 27, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/29181317/a-predictive-score-for-retinopathy-of-prematurity-by-using-clinical-risk-factors-and-serum-insulin-like-growth-factor-1-levels
#19
Yeşim Coşkun, Ceyhun Dalkan, Özge Yabaş, Özlem Ünay Demirel, Elif Samiye Bayar, Sibel Sakarya, Tuba Müftüoğlu, Dilaver Erşanlı, Nerin Bahçeciler, İpek Akman
AIM: To detect the impact of insulin-like growth factor-1 (IGF-1) and other risk factors for the early prediction of retinopathy of prematurity (ROP) and to establish a scoring system for ROP prediction by using clinical criteria and serum IGF-1 levels. METHODS: The study was conducted with 127 preterm infants. IGF-1 levels in the 1st day of life, 1st, 2nd, 3rd and 4th week of life was analyzed. The score was established after logistic regression analysis, considering the impact of each variable on the occurrences of any stage ROP...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29168321/effect-of-fetal-and-infant-growth-on-respiratory-symptoms-in-preterm-born-children
#20
John Lowe, Sarah J Kotecha, William J Watkins, Sailesh Kotecha
OBJECTIVES: Fetal growth and rapid postnatal weight gain are associated with adverse respiratory outcomes in childhood. However, the preterm-born population is less well studied. We assessed if the increased respiratory symptoms associated with altered fetal growth and infant weight gain were mediated by early factors. STUDY DESIGN: We used data from our cohort of preterm- and term-born (n = 4284 and 2865) children, aged 1-10 years. Respiratory outcomes obtained from a respiratory questionnaire were regressed on measures of fetal growth and infant weight gain, defined as >0...
November 23, 2017: Pediatric Pulmonology
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