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Brainstem implantation

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https://www.readbyqxmd.com/read/28443060/the-vestibular-implant-hearing-preservation-during-intralabyrinthine-electrode-insertion-a-case-report
#1
Raymond van de Berg, Florence Lucieer, Nils Guinand, Joost van Tongeren, Erwin George, Jean-Philippe Guyot, Herman Kingma, Marc van Hoof, Yasin Temel, Jacobus van Overbeeke, Angelica Perez-Fornos, Robert Stokroos
OBJECTIVE: The vestibular implant seems feasible as a clinically useful device in the near future. However, hearing preservation during intralabyrinthine implantation remains a challenge. It should be preserved to be able to treat patients with bilateral vestibulopathy and (partially) intact hearing. This case study investigated the feasibility of hearing preservation during the acute phase after electrode insertion in the semicircular canals. METHODS: A 40-year-old woman with normal hearing underwent a translabyrinthine approach for a vestibular schwannoma Koos Grade IV...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28420277/device-optimised-chirp-stimulus-for-abr-measurements-with-an-active-middle-ear-implant
#2
Mario Cebulla, Ute Geiger, Rudolf Hagen, Andreas Radeloff
OBJECTIVE: Active middle ear implants are widely used to treat adults and children with sensorineural, conductive, or mixed hearing loss. Currently, there is no adequate method to determine the performance of active middle ear implant systems. DESIGN: The proposed method is based on measuring the auditory brainstem response while stimulating the hearing system via the active middle ear implant (Vibrant Soundbridge(TM), VSB; MEDEL, Austria). The acoustic stimulation was achieved via an optimised chirp stimulus (CE-Chirp), implemented in the Eclipse system (Interacoustics, Denmark)...
April 19, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28371358/hearing-optimization-in-neurofibromatosis-type-2-a-systematic-review
#3
Simon Kingsley Wickham Lloyd, Andrew Thomas King, Scott Alexander Rutherford, Charlotte Lucy Hammerbeck-Ward, Simon Richard MacKenzie Freeman, Deborah Jane Mawman, Martin O'Driscoll, Dafydd Gareth Evans
BACKGROUND: It is common for patients with Neurofibromatosis type 2 to develop bilateral profound hearing loss hearing loss and this is one of the main determinants of quality of life in this patient group. OBJECTIVES: The aim of this systematic review was to review the current literature regarding hearing outcomes of treatments for vestibular schwannomas in neurofibromatosis type 2 including conservative and medical management, radiotherapy, hearing preservation surgery and auditory implantation in order to determine the most effective way of preserving or rehabilitating hearing Search Strategy: A MESH search in PubMed using search terms (("Neurofibromatosis 2"[Mesh]) AND "Neuroma, Acoustic"[Mesh]) AND "Hearing Loss"[Mesh] was performed...
April 1, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28362674/human-frequency-following-responses-to-vocoded-speech
#4
Saradha Ananthakrishnan, Xin Luo, Ananthanarayan Krishnan
OBJECTIVES: Vocoders offer an effective platform to simulate the effects of cochlear implant speech processing strategies in normal-hearing listeners. Several behavioral studies have examined the effects of varying spectral and temporal cues on vocoded speech perception; however, little is known about the neural indices of vocoded speech perception. Here, the scalp-recorded frequency following response (FFR) was used to study the effects of varying spectral and temporal cues on brainstem neural representation of specific acoustic cues, the temporal envelope periodicity related to fundamental frequency (F0) and temporal fine structure (TFS) related to formant and formant-related frequencies, as reflected in the phase-locked neural activity in response to vocoded speech...
March 30, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28357188/audiological-findings-from-an-adult-with-thin-cochlear-nerves
#5
Prashanth Prabhu, Jyothi Shivaswamy
Reported here are audiological findings from an adult with thin cochlear nerves. Magnetic resonance imaging (MRI) revealed that he had a thinner cochlear nerve in the left ear than in the right ear. He had a higher degree of hearing loss in the left ear and poor speech recognition scores for both ears. He had normal middle ear and cochlear functioning. The auditory brainstem response and acoustic reflexes were absent, indicating a retrocochlear pathology. Long latency responses (LLR) revealed normal cortical functioning...
February 2017: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/28355382/satisfaction-and-quality-of-life-in-users-of-auditory-brainstem-implant
#6
Nayara Freitas Fernandes, Maria Valéria Schmidt Goffi-Gomez, Ana Tereza De Matos Magalhães, Robinson Koji Tsuji, Rubens Vuono De Brito, Ricardo Ferreira Bento
Purpose To evaluate satisfaction and quality of life of users of Auditory Implant Brainstem. Methods This is a cross-sectional and descriptive study conducted at Divisão de Clínica Otorrinolaringológica of Hospital das Clínicas of Faculdade de Medicina da Universidade de São Paulo, Brazil. For the research, 19 users of an Auditory Brainstem Implant answered the following questionnaires: KINDLR (Questionnaire for Measuring Health-Related Quality of Life in Children and Adolescents), for children and adolescents, their parents and/or caregivers; WHOQOL-BREF questionnaire, for adult participants; and the Satisfaction with Amplification in Daily Life (SADL) questionnaire culturally adapted to Brazilian Portuguese...
2017: CoDAS
https://www.readbyqxmd.com/read/28335700/cochlear-implants-in-the-management-of-hearing-loss-in-neurofibromatosis-type-2
#7
Frances Harris, James R Tysome, Neil Donnelly, Juliette Durie-Gair, Gemma Crundwell, Yu Chuen Tam, Richard D Knight, Zebunnisa H Vanat, Nicola Folland, Patrick Axon
OBJECTIVE: Review of cochlear implant (CI) outcomes in patients with Neurofibromatosis Type 2 (NF2), implanted in the presence of an ipsilateral vestibular schwannoma (VS). Hearing restoration was combined in some cases with a Bevacizumab regime. METHOD: Retrospective review of 12 patients, managed over the period 2009-2016, at a tertiary referral multidisciplinary NF2 clinic. The patients are grouped by hearing outcomes to explore likely protective factors, and to generate a proposed decision-making tool for the selection of either CI or Auditory Brainstem Implant (ABI)...
May 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/28297339/deformable-image-registration-and-interobserver-variation-in-contour-propagation-for-radiation-therapy-planning
#8
Adam C Riegel, Jeffrey G Antone, Honglai Zhang, Prachi Jain, Jagdeep Raince, Anthony Rea, Angelo M Bergamo, Ajay Kapur, Louis Potters
Deformable image registration (DIR) and interobserver variation inevitably introduce uncertainty into the treatment planning process. The purpose of the current work was to measure deformable image registration (DIR) errors and interobserver variability for regions of interest (ROIs) in the head and neck and pelvic regions. Measured uncertainties were combined to examine planning margin adequacy for contours propagated for adaptive therapy and to assess the trade-off of DIR and interobserver uncertainty in atlas-based automatic segmentation...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28292001/-implantable-bone-conduction-and-active-middle-ear-devices
#9
Markus Pirlich, Andreas Dietz, Sylvia Meuret, Mathias Hofer
In case of audiological and/or anatomical limitations in the provision of conventional hearing aids, semi- or fully-implantable hearing systems represent a modern therapy alternative. These hearing systems are divided according to their mode of action into active middle ear implants when stimulating the auditory ossicles or the round window, into bone conduction devices while stimulating the skull directly, into cochlear implants with direct acoustic stimulation to the cochlea with its auditory nerve and finally into auditory brainstem implants by bridging the peripheral auditory structures...
February 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28280470/acute-effect-of-central-administration-of-urotensin-ii-on-baroreflex-and-blood-pressure-in-conscious-normotensive-rabbits
#10
Kyungjoon Lim, Yusuke Sata, Kristy L Jackson, Sandra L Burke, Geoffrey A Head
In the present study, we examined the effects of central administration of Urotensin II on blood pressure, heart rate, and baroreceptor heart rate reflexes in conscious normotensive rabbits. Preliminary operations were undertaken to implant a balloon cuff on the inferior vena cava for baroreflex assessments and to implant cannula into the lateral and fourth ventricle. After 2 weeks of recovery cumulative dose response curves to Urotensin II (10, 100 ng, 1, 10, and 100 μg) given into the ventricles, or Ringer's solution as a vehicle were performed on separate days...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28269325/somatosensory-encoding-with-cuneate-nucleus-microstimulation-detection-of-artificial-stimuli
#11
Srihari Y Sritharan, Andrew G Richardson, Pauline K Weigand, Ivette Planell-Mendez, Xilin Liu, Hongjie Zhu, Milin Zhang, Jan Van der Spiegel, Timothy H Lucas
The sense of touch and proprioception are critical to movement control. After spinal cord injury, these senses may be restored with direct, electrical microstimulation of the brain as part of a complete sensorimotor neuroprosthesis. The present study was designed to test, in part, the hypothesis that the cuneate nucleus (CN) of the brainstem is a suitable site to encode somatosensory information. Two rhesus macaques were implanted with microelectrode arrays providing chronic access to the CN. The monkeys were trained on an active touch oddity task to detect vibrotactile stimuli...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269101/detection-of-binaural-interaction-in-free-field-evoked-auditory-brainstem-responses-by-time-scale-representations
#12
Erik Schebsdat, Horst Hessel, Harald Seidler, Daniel J Strauss
The so called β-wave of the binaural interaction component (BIC) in auditory brainstem responses (ABR) has been shown to be an objective measure for binaural interaction (BI). This component is the arithmetical difference between the sum of the monaurally evoked ABRs and the binaurally evoked ABR. Unfortunately, these neural responses are known to be very fragile and as a result the calculated BIC. An additional issue is, that the findings of this measurement are predominantly needed in people with hearing loss who may use hearing devices like hearing aids (HA) or cochlear implants (CI), thus they are not able to use headphones (like in conventional ABR measurements) during the detection of possible BI...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28236065/glioblastoma-spheroids-produce-infiltrative-gliomas-in-the-rat-brainstem
#13
Zhiping Zhou, Neal Luther, Ranjodh Singh, John A Boockvar, Mark M Souweidane, Jeffrey P Greenfield
PURPOSE: Diffuse intrinsic pontine glioma (DIPG) is universally fatal without proven therapy other than radiation therapy for palliation. Representative animal models will play an essential role in the preclinical stage of future therapy development. To address the shortage of representative models, we created a novel infiltrative brainstem glioma model in rats based on glioblastoma spheroids. METHODS: Cells dissociated from glioblastoma spheroids grown from surgical specimens were implanted into the brainstem of NIH nude rats...
March 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28227566/somatosensory-encoding-with-cuneate-nucleus-microstimulation-detection-of-artificial-stimuli
#14
Srihari Y Sritharan, Andrew G Richardson, Pauline K Weigand, Ivette Planell-Mendez, Xilin Liu, Hongjie Zhu, Milin Zhang, Jan Van der Spiegel, Timothy H Lucas, Srihari Y Sritharan, Andrew G Richardson, Pauline K Weigand, Ivette Planell-Mendez, Xilin Liu, Hongjie Zhu, Milin Zhang, Jan Van der Spiegel, Timothy H Lucas, Srihari Y Sritharan, Andrew G Richardson, Milin Zhang, Jan Van der Spiegel, Pauline K Weigand, Xilin Liu, Timothy H Lucas, Hongjie Zhu, Ivette Planell-Mendez
The sense of touch and proprioception are critical to movement control. After spinal cord injury, these senses may be restored with direct, electrical microstimulation of the brain as part of a complete sensorimotor neuroprosthesis. The present study was designed to test, in part, the hypothesis that the cuneate nucleus (CN) of the brainstem is a suitable site to encode somatosensory information. Two rhesus macaques were implanted with microelectrode arrays providing chronic access to the CN. The monkeys were trained on an active touch oddity task to detect vibrotactile stimuli...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227326/detection-of-binaural-interaction-in-free-field-evoked-auditory-brainstem-responses-by-time-scale-representations
#15
Erik Schebsdat, Horst Hessel, Harald Seidler, Daniel J Strauss, Erik Schebsdat, Horst Hessel, Harald Seidler, Daniel J Strauss, Horst Hessel, Erik Schebsdat, Harald Seidler, Daniel J Strauss
The so called β-wave of the binaural interaction component (BIC) in auditory brainstem responses (ABR) has been shown to be an objective measure for binaural interaction (BI). This component is the arithmetical difference between the sum of the monaurally evoked ABRs and the binaurally evoked ABR. Unfortunately, these neural responses are known to be very fragile and as a result the calculated BIC. An additional issue is, that the findings of this measurement are predominantly needed in people with hearing loss who may use hearing devices like hearing aids (HA) or cochlear implants (CI), thus they are not able to use headphones (like in conventional ABR measurements) during the detection of possible BI...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28210535/magnetic-resonance-imaging-in-a-neurofibromatosis-type-2-patient-with-a-novel-mri-compatible-auditory-brainstem-implant
#16
REVIEW
Matthew Shew, Judson Bertsch, Paul Camarata, Hinrich Staecker
Auditory brainstem implantation has become a key technique for the rehabilitation of hearing in patients with neurofibromatosis type 2. The nature of this devastating genetic disease requires ongoing MRI for the patient's lifespan. Today, most auditory brainstem implants require removal of the magnet that connects the internal device to the external speech processor to undergo imaging as their disease progresses. Patients have the option of having a short procedure to have the magnet taken out and replaced each time, or alternately using a headband to secure the processor over the receiver coil of the internal device...
January 2017: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/28209771/hearing-loss-in-children-with-asymptomatic-congenital-cytomegalovirus-infection
#17
Tatiana M Lanzieri, Winnie Chung, Marily Flores, Peggy Blum, A Chantal Caviness, Stephanie R Bialek, Scott D Grosse, Jerry A Miller, Gail Demmler-Harrison
OBJECTIVES: To assess the prevalence, characteristics, and risk of sensorineural hearing loss (SNHL) in children with congenital cytomegalovirus infection identified through hospital-based newborn screening who were asymptomatic at birth compared with uninfected children. METHODS: We included 92 case-patients and 51 controls assessed by using auditory brainstem response and behavioral audiometry. We used Kaplan-Meier survival analysis to estimate the prevalence of SNHL, defined as ≥25 dB hearing level at any frequency and Cox proportional hazards regression analyses to compare SNHL risk between groups...
March 2017: Pediatrics
https://www.readbyqxmd.com/read/28185669/electrical-stimulation-and-monitoring-devices-of-the-cns-an-imaging-review
#18
REVIEW
Sohil H Patel, Casey H Halpern, Timothy M Shepherd, Vincent M Timpone
Functional neurosurgery is a rapidly growing field with exciting future potential applications. This article describes currently used implanted electronic devices for neurologic stimulation and monitoring. The devices to be reviewed include invasive EEG electrodes, deep brain stimulator, motor cortex stimulator, responsive neurostimulation, osteo-integrated hearing aid, middle ear implant, cochlear implant, auditory brainstem implant, vagal nerve stimulator and spinal cord stimulator. Emphasis is placed on the normal components, function, positioning, potential complications and MRI safety of these devices...
February 6, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28174524/ups-and-downs-in-75-years-of-electrocochleography
#19
REVIEW
Jos J Eggermont
Before 1964, electrocochleography (ECochG) was a surgical procedure carried out in the operating theatre. Currently, the newest application is also an intra-operative one, often carried out in conjunction with cochlear implant surgery. Starting in 1967, the recording methods became either minimal- or not-invasive, i.e., trans-tympanic (TT) or extra tympanic (ET), and included extensive studies of the arguments pro and con. I will review several valuable applications of ECochG, from a historical point of view, but covering all 75 years if applicable...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/28159538/the-effect-of-systemic-lipoic-acid-on-hearing-preservation-after-cochlear-implantation-via-the-round-window-approach-a-guinea-pig-model
#20
Mun Young Chang, Tae Mok Gwon, Ho Sun Lee, Jun Ho Lee, Seung Ha Oh, Sung June Kim, Min-Hyun Park
The present study aimed to evaluate the effects of systemic lipoic acid on hearing preservation after cochlear implantation. Twelve Dunkin-Hartley guinea pigs were randomly divided into two groups: the control group and the lipoic acid group. Animals in the lipoic acid group received lipoic acid intraperitoneally for 4 weeks. A sterilised silicone electrode-dummy was inserted through the round window to a depth of approximately 5 mm. The hearing level was measured using auditory brainstem responses (ABRs) prior to electrode-dummy insertion, and at 4 days and 1, 2, 3 and 4 weeks after electrode-dummy insertion...
January 31, 2017: European Journal of Pharmacology
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