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https://www.readbyqxmd.com/read/28445778/the-impact-of-bilateral-vagotomy-on-the-physostigmine-induced-airway-constriction-in-ferrets
#1
Burim Neziri, Armond Daci, Shaip Krasniqi, Ramadan Sopi, Musa A Haxhiu
Vagal innervations have a great role in the respiratory function and are the main route of signal transmission from respiratory neural centers into the trachea and others conducting airways. We have investigated the role of central mechanisms related to vagal neural pathways and the cholinergic outflow in tracheobronchial smooth muscle tone and lung mechanics parameters. Parameters of lung mechanics such as lung resistance (RL), dynamic compliance (Cdyn) and pressure in bypassed tracheal segment (Ptseg) were measured before and after vagotomy and asphyxia test...
April 23, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28439953/feasibility-trial-for-primary-stroke-prevention-in-children-with-sickle-cell-anemia-in-nigeria-spin-trial
#2
Najibah Galadanci, Shehu Umar Abdullahi, Leah D Vance, Abdulkadir Musa Tabari, Shehi Ali, Raymond Belonwu, Auwal Salihu, Aisha Amal Galadanci, Binta Wudil Jibir, Halima Bello-Manga, Kathleen Neville, Fenella J Kirkham, Yu Shyr, Sharon Phillips, Brittany V Covert, Adetola A Kassim, Lori C Jordan, Muktar H Aliyu, Michael R DeBaun
The vast majority of children with sickle cell anemia (SCA) live in Africa, where evidence-based guidelines for primary stroke prevention are lacking. In Kano, Nigeria, we conducted a feasibility trial to determine the acceptability of hydroxyurea therapy for primary stroke prevention in children with abnormal transcranial Doppler (TCD) measurements. Children with SCA and abnormal non-imaging TCD measurements (≥ 200 cm/s) received moderate fixed-dose hydroxyurea therapy (∼20 mg/kg/day). A comparison group of children with TCD measurements < 200 cm/s was followed prospectively...
April 25, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28429905/maintenance-vitamin-d3-dosage-requirements-in-chinese-women-with-post-menopausal-osteoporosis-living-in-the-tropics
#3
Yogeswari Venugopal, Sharifah F Wan Muhamad Hatta, Nurbazlin Musa, Siti Abdul Rahman, Jeyakantha Ratnasingam, Sharmila Sunita Paramasivam, Lee Ling Lim, Luqman Ibrahim, Karen Choong, Alexander Tb Tan, Karuthan Chinna, Siew Pheng Chan, Shireene R Vethakkan
BACKGROUND AND OBJECTIVES: Vitamin D3 (cholecalciferol) dose required to maintain sufficiency in non- Caucasian women with postmenopausal osteoporosis (PMO) inthe tropics has not been well studied. Some guidelines mandate 800-1000 IU vitamin D/day but the Endocrine Society (US) advocates 1500-2000 IU/day to maintain 25-hydroxyvitamin-D (25(OH)D) concentration at >75 nmol/L. We aimed to establish oral cholecalciferol dose required to maintain 25(OH)D concentration at >75 nmol/L in PMO Chinese Malaysian women, postulating lower dose requirements amongst light-skinned subjects in the tropics...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28429268/mutagenicity-assessment-of-aerosols-in-emissions-from-domestic-combustion-processes
#4
EDITORIAL
Nuno Canha, Isabel Lopes, Estela Domingos Vicente, Ana M Vicente, Benjamin A Musa Bandowe, Susana Marta Almeida, Célia A Alves
No abstract text is available yet for this article.
April 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28422663/a-neural-probe-with-up-to-966-electrodes-and-up-to-384-configurable-channels-in-0-13-%C3%AE-m-soi-cmos
#5
Carolina Mora Lopez, Jan Putzeys, Bogdan Cristian Raducanu, Marco Ballini, Shiwei Wang, Alexandru Andrei, Veronique Rochus, Roeland Vandebriel, Simone Severi, Chris Van Hoof, Silke Musa, Nick Van Helleputte, Refet Firat Yazicioglu, Srinjoy Mitra
In vivo recording of neural action-potential and local-field-potential signals requires the use of high-resolution penetrating probes. Several international initiatives to better understand the brain are driving technology efforts towards maximizing the number of recording sites while minimizing the neural probe dimensions. We designed and fabricated (0.13- μm SOI Al CMOS) a 384-channel configurable neural probe for large-scale in vivo recording of neural signals. Up to 966 selectable active electrodes were integrated along an implantable shank (70 μm wide, 10 mm long, 20  μm thick), achieving a crosstalk of [Formula: see text] dB...
April 14, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28421305/the-utility-of-global-longitudinal-strain-in-the-identification-of-prior-myocardial-infarction-in-patients-with-preserved-left-ventricular-ejection-fraction
#6
Graham J Fent, Pankaj Garg, James R J Foley, Laura E Dobson, Tarique A Musa, Bara Erhayiem, John P Greenwood, Sven Plein, Peter P Swoboda
Prior myocardial infarction (MI) is associated with increased mortality and is prevalent in certain high risk patient groups. Electrocardiogram may be used in diagnosis, however, sensitivity is limited, thus non-invasive imaging techniques may improve diagnosis. We investigated whether global longitudinal strain (GLS) and longitudinal strain parameters are reduced in patients with prior MI but preserved left ventricular ejection fraction (LVEF). The study included 40 clinical patients with prior MI occurring >3 months previously (defined as subendocardial hyperenhancement on late Gadolinium enhancement imaging) with LVEF ≥ 55% and 40 controls matched for age and LVEF...
April 18, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28417685/independent-socio-demographic-and-clinical-correlates-associated-with-the-perception-of-quality-of-life-of-women-with-postpartum-depressionin-north-central-nigeria
#7
Friday Tungchama, Christopher Piwuna, Aishatu Armiya'u, Yusufu Maigari, Francis Davou, Suwa Goar, Musa Umar, Suleiman Sadiq, Emmanuel Ojih, Richard Uwakwe
OBJECTIVE: Quality of life (QoL) is probably the most desired outcome of all health care policies and monitoring. This concept is seldom used on women in the postpartum, especially in the developing world. AIM: This study aimed at determining the independent socio-clinical variables associated with the perception of QoL of women with postpartum depression. METHODS: A two-stage cross-sectional procedure was used to recruit 550 participants, out of whom 531 participants completed the questionnaires with 116 participants found to have postpartum depression and were the studied population, in Nigeria...
April 18, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28415629/a-h1n1-pdm09-influenza-infection-vaccine-inefficiency
#8
Nehemya Friedman, Yaron Drori, Rakefet Pando, Aharona Glatman-Freedman, Hanna Sefty, Ravit Bassal, Yaniv Stein, Tamy Shohat, Ella Mendelson, Musa Hindiyeh, Michal Mandelboim
The last influenza pandemic, caused by the swine A(H1N1)pdm09 influenza virus, began in North America at 2009. Since then, the World Health Organization (WHO) recommended integration of the swine-based virus A/California/07/2009 strain in yearly vaccinations. Yet, infections with A(H1N1)pdm09 have continued in subsequent years. The reasons for this are currently unknown. During the 2015-2016 influenza season, we noted an increased prevalence of A(H1N1)pdm09 influenza virus infection in Israel. Our phylogenetic analysis indicated that the circulating A(H1N1)pdm09 strains belonged to 6B...
March 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28412523/progenitor-strain-introduction-of-mycobacterium-bovis-at-the-wildlife-livestock-interface-can-lead-to-clonal-expansion-of-the-disease-in-a-single-ecosystem
#9
Anzaan Dippenaar, Sven David Charles Parsons, Michele Ann Miller, Tiny Hlokwe, Nicolaas Claudius Gey van Pittius, Sabir Abdu Adroub, Abdallah Musa Abdallah, Arnab Pain, Robin Mark Warren, Anita Luise Michel, Paul David van Helden
Mycobacterium bovis infects multiple wildlife species and domesticated cattle across South Africa, and negatively impacts on livestock trade and movement of wildlife for conservation purposes. M. bovis infection was first reported in the Kruger National Park (KNP) in South Africa during the 1990s, and has since spread to infect numerous animal host species throughout the park and across South Africa. Whole genome sequencing data of 17 M. bovis isolates were analyzed to investigate the genomic diversity among M...
April 13, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28410462/health-service-provision-for-people-with-epilepsy-in-sub-saharan-africa-a-situational-review
#10
REVIEW
Musa M Watila, Mark R Keezer, Samuel A Angwafor, Andrea S Winkler, Josemir W Sander
BACKGROUND: Epilepsy is a public health issue in sub-Saharan Africa (SSA) where many people with the condition receive no treatment. Health-care services for epilepsy in this region have not been comprehensively assessed. We examined key features of epilepsy health services provided in SSA. METHODOLOGY: This was a scoping review conducted using pre-specified protocols. We implemented an electronic search strategy to identify relevant citations using PUBMED, EMBASE, Web of Science, Scopus, Cumulative Index to Nursing and Allied Health Literature (CINAHL), African Index Medicus (AIM), Open Grey, Cochrane database, and Google Scholar...
April 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28406128/variations-in-the-%C3%AE-globin-genes-of-sickle-cell-anaemia-patients-in-zaria-northwestern-nigeria
#11
S Awwalu, A I Mamman, A Hassan, L G Dogara, A D Waziri, S M Aminu, A U Musa, H Bello-Manga
CONTEXT: Sickle Cell Anaemia (SCA) is a genetic disorder with a life-long disability, which is of public health importance. The diversity in its clinico-pathologic and laboratory presentations may be due to the interplay between additional genetic differences and environmental factors. The genetic factors may be within the β-globin gene itself, the β-globin gene cluster or elsewhere in the genome. AIM: To characterize the β-globin gene for variations associated with the Sickle Cell mutation...
April 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28405838/acaricidal-and-sublethal-effects-of-a-chenopodium-based-biopesticide-on-the-two-spotted-spider-mite-acari-tetranychidae
#12
Asma Musa, Irena Međo, Ivana Marić, Dejan Marčić
Acaricidal and sublethal effects of the biopesticide Requiem(®)EC (containing an essential oil extract of Chenopodium ambrosioides near ambrosioides) on the two-spotted spider mite, Tetranychus urticae Koch, were evaluated in laboratory bioassays. The biopesticide was applied to bean leaves or leaf discs using a Potter spray tower. Acaricidal activity against eggs and immatures was evaluated in successive acute toxicity bioassays. Concentration-mortality data were subjected to probit analysis and the following LC50 values (ml/l) were calculated: 2...
April 12, 2017: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/28405165/enhancement-of-physicochemical-properties-of-nanocolloidal-carrier-loaded-with-cyclosporine-for-topical-treatment-of-psoriasis-in-vitro-diffusion-and-in-vivo-hydrating-action
#13
Siti Hajar Musa, Mahiran Basri, Hamid Reza Fard Masoumi, Norashikin Shamsudin, Norazlinaliza Salim
Psoriasis is a chronic autoimmune disease that cannot be cured. It can however be controlled by various forms of treatment, including topical, systemic agents, and phototherapy. Topical treatment is the first-line treatment and favored by most physicians, as this form of therapy has more patient compliance. Introducing a nanoemulsion for transporting cyclosporine as an anti-inflammatory drug to an itchy site of skin disease would enhance the effectiveness of topical treatment for psoriasis. The addition of nutmeg and virgin coconut-oil mixture, with their unique properties, could improve cyclosporine loading and solubility...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28395264/polycyclic-aromatic-hydrocarbons-and-their-derivatives-nitro-pahs-oxygenated-pahs-and-azaarenes-in-pm2-5-from-southern-european-cities
#14
Célia A Alves, Ana M Vicente, Danilo Custódio, Mário Cerqueira, Teresa Nunes, Casimiro Pio, Franco Lucarelli, Giulia Calzolai, Silvia Nava, Evangelia Diapouli, Konstantinos Eleftheriadis, Xavier Querol, Benjamin A Musa Bandowe
Atmospheric particulate matter (PM2.5) samples were collected over two one month periods during winter and summer in three Southern European cities (Oporto - traffic site, Florence - urban background, Athens - suburban). Concentrations of 27 polycyclic aromatic hydrocarbons (PAHs), 15 nitro-PAHs (NPAHs), 15 oxygenated-PAHs (OPAHs) and 4 azaarenes (AZAs) were determined. On average, the winter-summer concentrations of ΣPAHs were 16.3-5.60, 7.75-3.02 and 3.44-0.658ngm(-3) in Oporto, Florence and Athens, respectively...
April 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28373803/evaluation-of-glutamic-acid-decarboxylase-antibody-levels-in-patients-with-juvenile-myoclonic-epilepsy-and-mesial-temporal-lobe-epilepsy-with-hippocampal-sclerosis
#15
Ayten Ceyhan Dirican, Sevilay Elibirlik, Ayhan Köksal, Musa Öztürk, Yavuz Altunkaynak, Sevim Baybaş, Ahmet Dirican
INTRODUCTION: Several clinical studies have been conducted to investigate the role of autoantibodies and immunological mechanisms in the etiology of treatment-resistant epilepsy in recent years. Some immunological treatments have been suggested as a result of these studies. In this study, we aimed to investigate the role of autoimmunity in partial and idiopathic generalized epilepsy and determine the relationship between drug resistance and autoimmune antibodies. METHODS: Twenty-eight patients (24 treatment-responsive and 4 treatment-resistant) with juvenile myoclonic epilepsy (JME), 26 patients with mesial temporal lobe epilepsy with hippocampal sclerosis (MTLEHS) resistant to antiepileptic drug treatment, and 26 age-matched healthy control subjects were included in a two-year cross sectional study...
September 2016: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28370622/wri1-1-abi5-nf-ya3-and-nf-yc2-increase-oil-biosynthesis-in-coordination-with-hormonal-signaling-during-fruit-development-in-oil-palm
#16
Wan-Chin Yeap, Fong-Chin Lee, Dilip Kumar Shabari Shan, Hamidah Musa, David Ross Appleton, Harikrishna Kulaveerasingam
The oil biosynthesis pathway must be tightly controlled to maximize oil yield. Oil palm accumulates exceptionally high oil content in its mesocarp, suggesting the existence of a unique fruit-specific fatty acid metabolism transcriptional network. We report the complex fruit-specific network of transcription factors responsible for modulation of oil biosynthesis genes in oil palm mesocarp. Transcriptional activation of EgWRI1-1 encoding a key master regulator that activates expression of oil biosynthesis genes, is activated by three ABA-responsive transcription factors, EgNF-YA3, EgNF-YC2 and EgABI5...
March 29, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28370072/expression-profiling-of-sudanese-visceral-leishmaniasis-patients-pre-and-post-treatment-with-sodium-stibogluconate
#17
Mohamed A M Salih, Michaela Fakiola, Paul A Lyons, Brima M Younis, Ahmed M Musa, Ahmed M Elhassan, Denise Anderson, Genevieve Syn, Muntaser E Ibrahim, Jenefer M Blackwell, Hiba S Mohamed
Visceral leishmaniasis (VL) in Sudan caused by Leishmania donovani is fatal in susceptible individuals if untreated. Treatment with Sodium Stibogluconate (SSG) leads to post kala azar dermal leishmaniasis (PKDL) in 58% of patients. Here Affymetrix microarrays were used to identify genes differentially expressed in lymph nodes (N=9 paired samples) pre- and post-treatment with SSG. Using the Bioconductor package limma, 438 genes from 28,869 post quality-control probe-sets were differentially expressed (Pnominal ≤0...
March 31, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28369799/effect-of-dental-pulp-stem-cells-in-mptp-induced-old-aged-mice-model
#18
Nareshwaran Gnanasegaran, Vijayendran Govindasamy, Christopher Simon, Quan Fu Gan, Vui King Vincent-Chong, Vasudevan Mani, Kesavanarayanan Krishnan Selvarajan, Vellayan Subramaniam, Sabri Musa, Noor Hayaty Abu Kasim
Parkinson's disease (PD) is a neurodegenerative disease caused by the loss of dopaminergic (DA-ergic) neurons in the substantia nigra (SN) and represent as a huge threat to the geriatric population. Cell-replacement therapies (CRTs) have been proposed as a promising strategy to slow down or replace neuronal loss. Among the widely available cell sources, dental pulp stem cells (DPSCs) portray as an attractive source primarily due to their neural crest origin, ease of tissue procurement and less ethical hurdles MATERIALS AND METHODS: We first demonstrated the in vitro differentiation ability of DPSCs towards DA-ergic-like cells before evaluating their neuro-protection/neuro-restoration capacities in MPTP-induced mice...
March 30, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28367666/suppression-of-vegf-induced-angiogenesis-and-tumor-growth-by-eugenia-jambolana-musa-paradisiaca-and-coccinia-indica-extracts
#19
Harsha Raj M, Debidas Ghosh, Rita Banerjee, Bharathi P Salimath
CONTEXT: Abnormal angiogenesis and evasion of apoptosis are hallmarks of cancer. Accordingly, anti-angiogenic and pro-apoptotic therapies are effective strategies for cancer treatment. Medicinal plants, namely, Eugenia jambolana Lam. (Myrtaceae), Musa paradisiaca L. (Musaceae), and Coccinia indica Wight & Arn. (Cucurbitaceae), have not been greatly investigated for their anticancer potential. OBJECTIVE: We investigated the anti-angiogenic and pro-apoptotic efficacy of ethyl acetate (EA) and n-butanol (NB) extracts of E...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28367045/neutrophil-to-lymphocyte-ratio-in-patients-with-nonarteritic-anterior-ischemic-optic-neuropathy
#20
Alime Gunes, Musa Yigit, Levent Tok, Ozlem Tok
PURPOSE: To evaluate the neutrophil to lymphocyte ratio (NLR) in patients with nonarteritic anterior ischemic optic neuropathy (NAION). METHODS: We investigated 112 subjects comprising 56 patients with NAION and 56 healthy controls at Süleyman Demirel University. Complete blood count, demographic, and clinic data from NAION patients were evaluated in this study. The NLR was calculated in all individuals and compared between the patient and control groups. Cut-off values were also determined...
April 2017: Korean Journal of Ophthalmology: KJO
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