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https://www.readbyqxmd.com/read/28338344/new-flavonol-glycoside-from-scabiosa-prolifera-l-aerial-parts-with-in-vitro-antioxidant-and-cytotoxic-activities
#1
Mahmoud A Al-Qudah, Noor K Otoom, Hala I Al-Jaber, Ayman M Saleh, Musa H Abu Zarga, Fatma U Afifi, Sultan T Abu Orabi
Phytochemical investigation of the chemical constituents of the aerial parts of Scabiosa prolifera L. led to the isolation of one new flavonol glycoside, kaempferol-3-O-(4″,6″-di-E-p-coumaroyl)-β-D-galactopyranoside (1), along with ten other known compounds including luteolin-7-O-(2″-O-ethyl-β-glucopyranoside), β-sitosterol, β-sitosterylglucoside, ursolic acid, corosolic acid, ursolic acid 3-O-β-D-arabinopyranoside, apigenin, methyl-α-D-glucopyranoside, luteolin-7-O-β-glucopyranoside and isoorientin...
March 24, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28336277/structure-characteristics-of-an-acidic-polysaccharide-purified-from-banana-musa-nana-lour-pulp-and-its-enzymatic-degradation
#2
Huiling Liu, Yueming Jiang, Hongshun Yang, Bao Yang
Banana is one of the most important fruits over the world. The chemical composition is critical for the organoleptic properties and health benefits. As one of the leading bioactive components in banana pulp, the polysaccharides may contribute to the beneficial health effects. However, their precise structure information remains unknown. A leading acidic polysaccharide (ABPP) of banana pulp was purified and identified by nuclear magnetic resonnance spectroscopy (NMR) and gas chromatography-mass spectrometry (GC-MS)...
March 20, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28330106/enhanced-production-of-pectinase-by-aspergillus-terreus-ncft-4269-10-using-banana-peels-as-substrate
#3
Bijay Kumar Sethi, Prativa Kumari Nanda, Santilata Sahoo
Aspergillus terreus NCFT4269.10 was implemented in solid-state (SSF) and liquid static surface fermentation (LSSF) for biosynthesis of pectinase. Amongst various substrates, like, mustard oil cake, neem oil cake, groundnut oil cake, black gram peels, green gram peels, chickling vetch peels/grass pea peels wheat bran, pearl millet residues, finger millet waste, broken rice, banana peels (BP), apple pomace (AP) and orange peels, banana peel (Musa paradisiaca L.; Family: Musaceae) was most suitable for pectinase biosynthesis (LSSF: 400 ± 21...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28330078/potential-of-trichoderma-harzianum-for-control-of-banana-leaf-fungal-pathogens-when-applied-with-a-food-source-and-an-organic-adjuvant
#4
Suren Samuelian
Trichoderma isolates were obtained from diseased leaves and fruit collected from plantations in the main banana production area in Northern Queensland. Phylogenetic analyses identified the Trichoderma isolates as T. harzianum and T. virens. The Trichoderma spp. were found to be antagonistic against the banana leaf pathogens Mycosphaerella musicola, Cordana musae, and Deightoniella torulosa in vitro. Several products used by the banana industry to increase production, including molasses, Fishoil and Seasol, were tested as food source for the Trichoderma isolates...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28325331/two-banana-cultivars-differ-in-composition-of-potentially-immunomodulatory-mannan-and-arabinogalactan
#5
Tânia M Shiga, Nicholas C Carpita, Franco Maria Lajolo, Beatriz Rosana Cordenunsi-Lysenko
Banana (Musa acuminata and M. acuminata x M. balbisiana) fruit cell walls are rich in mannans, homogalacturonans and xylogalacturonan, rhamnogalacturonan-I, and arabinogalactans, certain forms of which is considered to have immunomodulatory activity. The cultivars Nanicão and Thap Maeo represent two widely variants with respect to compositional differences in the forms of these polysaccharides. Nanicão has low amounts of mannan in the water-insoluble and water-soluble fraction. Both cultivars have high amounts of water-soluble arabinogalactan...
May 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28321600/post-6-ohda-lesion-exposure-to-stress-affects-neurotrophic-factor-expression-and-aggravates-motor-impairment
#6
Phumzile Nomfundo Ngema, Musa Vuyisile Mabandla
Chronic exposure to stress amplifies locomotor deficits and exacerbates dopamine neuron loss in an animal model for Parkinson's disease. The release of neurotrophic factors such as glial cell-line derived neurotrophic factor (GDNF) and neurotrophin-3 (NT-3) following neuronal injury attenuates exacerbated degeneration of these neurons. In this study, the neurotoxin 6-hydroxydopamine (6-OHDA) was injected unilaterally into the medial forebrain bundle of male Sprague Dawley rats. A subset of these rats was subjected to post-lesion restraint stress after which the effect of exposure to stress on locomotor activity (forelimb akinesia test), neurotrophic factor (GDNF and NT-3) and corticosterone concentration was assessed...
March 20, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28318191/a-fatal-clostridium-perfringens-infection-with-hemolysis-after-chemotherapy-in-an-adolescent
#7
Musa G Kukul, Kısmet Ciki, Eda Karadag-Oncel, Ali B Cengiz, Baris Kuskonmaz, Betul Tavil, Selman Kesici
Gas gangrene, clostridial myonecrosis, is one of the most serious infectious diseases, characterized by rapidly progressive destruction of deep soft tissues and production of gas within the tissues. We presented a case of fatal spontaneous gas gangrene due to Clostridium perfringens in a patient with acute lymphoblastic leukemia during remission induction chemotherapy phase.
April 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28316310/three-port-two-located-on-the-pfannenstiel-line-laparoscopic-cholecystectomy-comparison-with-traditional-laparoscopic-cholecystectomy
#8
Musa Akoglu, Erdal Birol Bostanci, Muhammet Kadri Colakoglu, Erol Aksoy
Laparoscopic cholecystectomy (LC) is seen as a gateway to minimally invasive surgery. We defined a new three-port technique with different port sites and compared the postoperative results with traditional four-port LC procedure in a case-match study. Between June 2012 and May 2013, 104 consecutive patients underwent three-port LC by same experienced surgeon. In the same center, 2963 consecutive patients underwent four-port LC, and of these 2963 patients, a matched group of 104 patients was selected. Data included patient age, gender, body mass index, American Society of Anesthesiologists score, history of abdominal operations, intraoperative data about operating time and conversion to open surgery, and postoperative data about length of hospital stay and postoperative complications were recorded prospectively...
March 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28314047/the-role-of-risk-perception-in-flu-vaccine-behavior-among-african-american-and-white-adults-in-the-united-states
#9
Vicki S Freimuth, Amelia Jamison, Gregory Hancock, Donald Musa, Karen Hilyard, Sandra Crouse Quinn
Seasonal flu vaccination rates are low for U.S. adults, with significant disparities between African and white Americans. Risk perception is a significant predictor of vaccine behavior but the research on this construct has been flawed. This study addressed critical research questions to understand the differences between African and white Americans in the role of risk perception in flu vaccine behavior: (1) What is the dimensionality of risk perception and does it differ between the two races?  (2) Were risk perceptions of white and African-American populations different and how were sociodemographic characteristics related to risk for each group? (3) What is the relation between risk perception and flu vaccine behaviors for African Americans and whites? The sample, drawn from GfK's Knowledge Panel, consisted of 838 whites and 819 African Americans...
March 17, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28297074/cost-effectiveness-of-cervical-cancer-screening-methods-in-low-and-middle-income-countries-a-systematic-review
#10
REVIEW
Alex K Mezei, Heather L Armstrong, Heather N Pedersen, Nicole G Campos, Sheona M Mitchell, Musa Sekikubo, Josaphat K Byamugisha, Jane J Kim, Stirling Bryan, Gina S Ogilvie
The incidence of cervical cancer in low- and middle-income countries (LMICs) is five times higher than that observed in high-income countries (HICs). This discrepancy is largely attributed to the implementation of cytology-based screening programmes in HICs. However, due to reduced health system infrastructure requirements, HPV testing (self- and provider-collected), and visual inspection with acetic acid (VIA) have been proposed as alternatives that may be better suited to LMICs. Knowing the relative value of different screening options can inform policy and the development of sustainable prevention programs...
March 15, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28283442/transdermal-delivery-of-oleanolic-acid-attenuates-pro-inflammatory-cytokine-release-and-ameliorates-anaemia-in-p-berghei-malaria
#11
Happiness Sibiya, Cephas T Musabayane, Musa V Mabandla
Malaria remains a major health problem in many tropical areas. Severe malaria infection is associated with secondary complications including anaemia leading to a need for the search of affordable antimalarial agents that can clear the parasitaemia and ameliorate anaemia during infection. The current study investigated the effects of transdermally delivered OA on malaria parasites, HCT and selected plasma cytokine concentrations in P. berghei-infected male Sprague-Dawley rats. The study was carried out over a period of 21 days, divided into pre-treatment (day 0-7), treatment (day 8-12) and post-treatment (day 13-21) periods...
March 7, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28283061/functional-selectivity-in-cytokine-signaling-revealed-through-a-pathogenic-epo-mutation
#12
Ah Ram Kim, Jacob C Ulirsch, Stephan Wilmes, Ekrem Unal, Ignacio Moraga, Musa Karakukcu, Daniel Yuan, Shideh Kazerounian, Nour J Abdulhay, David S King, Namrata Gupta, Stacey B Gabriel, Eric S Lander, Turkan Patiroglu, Alper Ozcan, Mehmet Akif Ozdemir, K Christopher Garcia, Jacob Piehler, Hanna T Gazda, Daryl E Klein, Vijay G Sankaran
Cytokines are classically thought to stimulate downstream signaling pathways through monotonic activation of receptors. We describe a severe anemia resulting from a homozygous mutation (R150Q) in the cytokine erythropoietin (EPO). Surprisingly, the EPO R150Q mutant shows only a mild reduction in affinity for its receptor but has altered binding kinetics. The EPO mutant is less effective at stimulating erythroid cell proliferation and differentiation, even at maximally potent concentrations. While the EPO mutant can stimulate effectors such as STAT5 to a similar extent as the wild-type ligand, there is reduced JAK2-mediated phosphorylation of select downstream targets...
March 9, 2017: Cell
https://www.readbyqxmd.com/read/28276755/prevalence-of-trachoma-in-kano-state-nigeria-results-of-44-local-government-area-level-surveys
#13
Caleb Mpyet, Nasiru Muhammad, Mohammed Dantani Adamu, Habila Muazu, Murtala Muhammad Umar, Musa Goyol, Hadi Bala Yahaya, Uwazoeke Onyebuchi, Chris Ogoshi, Tijjani Hussaini, Sunday Isiyaku, Adamani William, Rebecca M Flueckiger, Brian K Chu, Rebecca Willis, Alexandre L Pavluck, Nicholas Olobio, Sophie Phelan, Colin Macleod, Anthony W Solomon
PURPOSE: We sought to determine the prevalence of trachoma in 44 Local Government Areas (LGAs) of Kano State, Nigeria. METHODS: A population-based prevalence survey was conducted in each Kano LGA. We used a two-stage systematic and quasi-random sampling strategy to select 25 households from each of 25 clusters in each LGA. All consenting household residents aged 1 year and above were examined for trachomatous inflammation-follicular (TF), trachomatous inflammation-intense (TI) and trichiasis...
February 28, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28275558/myocardial-strain-and-symptom-severity-in-severe-aortic-stenosis-insights-from-cardiovascular-magnetic-resonance
#14
Tarique Al Musa, Akhlaque Uddin, Peter P Swoboda, Pankaj Garg, Timothy A Fairbairn, Laura E Dobson, Christopher D Steadman, Anvesha Singh, Bara Erhayiem, Sven Plein, Gerald P McCann, John P Greenwood
BACKGROUND: Symptomatic severe aortic stenosis (AS) is a class I indication for replacement in patients when left ventricular ejection fraction (LVEF) is preserved. However, symptom reporting is often equivocal and decision making can be challenging. We aimed to quantify myocardial deformation using cardiovascular magnetic resonance (CMR) in patients classified by symptom severity. METHODS: Forty-two patients with severe AS referred to heart valve clinic were studied using tagged CMR imaging...
February 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28274015/anaphylaxis-complicated-by-acute-respiratory-distress-and-fatal-outcome-in-a-nigerian-family
#15
Efeturi Agelebe, Tawakalit Lily Musa, Idowu Adebowale Ajayi, Olusola Adetunji Oyedeji
Reports on hypersensitivity diseases in Nigerians are rare. We report the incidence of anaphylaxis in three siblings following fatal outcome in their mother. Urticarial rashes were noticed in three siblings' resident in a South Western Nigerian town, one week before presentation at our facility. All the three siblings developed respiratory distress four days after the rash was noticed. Onset of respiratory distress made the family seek care at a private hospital, where they were admitted and treated with intravenous aminophylline and ceftriaxone...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28265353/effects-of-pretreatments-of-banana-musa-aaa-omini-on-the-composition-rheological-properties-and-baking-quality-of-its-flour-and-composite-blends-with-wheat-flour
#16
Adegoke H Bakare, Olukemi D Ogunbowale, Mojisola O Adegunwa, Joseph O Olusanya
Effects of chemical and heat pretreatments on the protein, gluten, and alpha-amylase activity, pasting (Peak [P], Final [F] setback [S] viscosity, pasting temperature [PT] and time [T]) and alveogram (Energy [E], maximum inflation [MI], P/L, and elasticity index [EI]) properties of flour from the pretreated bananas and its composite with wheat flour (WF) were examined. The baking (water absorption [WA] and specific volume [SV]) and sensory properties of bread produced from the flour were also examined. Protein, gluten, and alpha-amylase activity ranged from 4...
March 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28263994/multi-objective-agv-scheduling-in-an-fms-using-a-hybrid-of-genetic-algorithm-and-particle-swarm-optimization
#17
Maryam Mousavi, Hwa Jen Yap, Siti Nurmaya Musa, Farzad Tahriri, Siti Zawiah Md Dawal
Flexible manufacturing system (FMS) enhances the firm's flexibility and responsiveness to the ever-changing customer demand by providing a fast product diversification capability. Performance of an FMS is highly dependent upon the accuracy of scheduling policy for the components of the system, such as automated guided vehicles (AGVs). An AGV as a mobile robot provides remarkable industrial capabilities for material and goods transportation within a manufacturing facility or a warehouse. Allocating AGVs to tasks, while considering the cost and time of operations, defines the AGV scheduling process...
2017: PloS One
https://www.readbyqxmd.com/read/28261773/is-surgery-necessary-to-confirm-diagnosis-of-right-sided-diverticulitis-in-spite-of-relevant-clinical-and-radiological-findings
#18
Erkan Yardımcı, Mustafa Hasbahçeci, Ufuk Oğuz İdiz, Musa Atay, Hüseyin Akbulut
BACKGROUND: Diverticulosis of the right colon is an uncommon entity. Aim of the present study was to report outcome in patients with right-sided diverticulitis diagnosed using computed tomography (CT) and treated conservatively. METHODS: Twelve patients with clinical and radiological diagnosis of cecal or right-sided diverticulitis who were treated conservatively between February 2013 and December 2014 were included. Demographic and clinical data were retrospectively analyzed...
January 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28257477/wealth-household-heterogeneity-and-livelihood-diversification-of-fulani-pastoralists-in-the-kachia-grazing-reserve-northern-nigeria-during-a-period-of-social-transition
#19
Marie J Ducrotoy, Crawford W Revie, Alexandra P M Shaw, Usman B Musa, Wilson J Bertu, Amahyel M Gusi, Reuben A Ocholi, Ayodele O Majekodunmi, Susan C Welburn
BACKGROUND: A mixed methods study was undertaken in the Kachia Grazing Reserve of northern Nigeria. Surveys in March, June and October 2011 included focus group discussions, key informant and in-depth household interviews, concerning livelihood practices, animal health, ownership, and productivity. In May 2011, 249 Fulani families fleeing post-election violence entered the reserve with their livestock, increasing the number of households by one third. RESULTS: Despite being settled within a grazing reserve, over half of households sent all their cattle away on seasonal transhumance and another third sent some away...
2017: PloS One
https://www.readbyqxmd.com/read/28255755/epigenetics-a-link-between-addiction-and-social-environment
#20
REVIEW
Duyilemi C Ajonijebu, Oualid Abboussi, Vivienne A Russell, Musa V Mabandla, William M U Daniels
The detrimental effects of drug abuse are apparently not limited to individuals but may also impact the vulnerability of their progenies to develop addictive behaviours. Epigenetic signatures, early life experience and environmental factors, converge to influence gene expression patterns in addiction phenotypes and consequently may serve as mediators of behavioural trait transmission between generations. The majority of studies investigating the role of epigenetics in addiction do not consider the influence of social interactions...
March 2, 2017: Cellular and Molecular Life Sciences: CMLS
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