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https://www.readbyqxmd.com/read/28716801/diabetes-mellitus-microalbuminuria-and-subclinical-cardiac-disease-identification-and-monitoring-of-individuals-at-risk-of-heart-failure
#1
Peter P Swoboda, Adam K McDiarmid, Bara Erhayiem, David P Ripley, Laura E Dobson, Pankaj Garg, Tarique A Musa, Klaus K Witte, Mark T Kearney, Julian H Barth, Ramzi Ajjan, John P Greenwood, Sven Plein
BACKGROUND: Patients with type 2 diabetes mellitus and elevated urinary albumin:creatinine ratio (ACR) have increased risk of heart failure. We hypothesized this was because of cardiac tissue changes rather than silent coronary artery disease. METHODS AND RESULTS: In a case-controlled observational study 130 subjects including 50 ACR+ve diabetes mellitus patients with persistent microalbuminuria (ACR >2.5 mg/mol in males and >3.5 mg/mol in females, ≥2 measurements, no previous renin-angiotensin-aldosterone therapy, 50 ACR-ve diabetes mellitus patients and 30 controls underwent cardiovascular magnetic resonance for investigation of myocardial fibrosis, ischemia and infarction, and echocardiography...
July 17, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28716555/attitudes-about-vaccines-to-prevent-ebola-virus-disease-in-guinea-at-the-end-of-a-large-ebola-epidemic-results-of-a-national-household-survey
#2
Kathleen L Irwin, Mohamed F Jalloh, Jamaica Corker, Barry Alpha Mahmoud, Susan J Robinson, Wenshu Li, Nyuma E James, Musa Sellu, Mohammad B Jalloh, Alpha Ahmadou Diallo, LaRee Tracy, Rana Hajjeh, Amanda VanSteelandt, Rebecca Bunnell, Lise Martel, Pratima L Raghunathan, Barbara Marston
INTRODUCTION: In 2014-2016, an Ebola epidemic devastated Guinea; more than 3800 cases and 2500 deaths were reported to the World Health Organization. In August 2015, as the epidemic waned and clinical trials of an experimental, Ebola vaccine continued in Guinea and neighboring Sierra Leone, we conducted a national household survey about Ebola-related knowledge, attitudes, and practices (KAP) and opinions about "hypothetical" Ebola vaccines. METHODS: Using cluster-randomized sampling, we selected participants aged 15+ years old in Guinea's 8 administrative regions, which had varied cumulative case counts...
July 14, 2017: Vaccine
https://www.readbyqxmd.com/read/28714347/antifungal-activities-and-active-ingredients-of-melodinus-suaveolens-champ-ex-benth
#3
Yanan Xu, Siquan Ling, Dongqiang Zeng, Wenwei Tang
Four Melodinus species with antifungal activity were found in survey of the floral resources, in Shiwan Mountain Natural Reserve, Guangxi Province, China. Crude methanolic extracts of the twigs and leaves of Melodinus suaveolens exhibited potent antifungal activities against the plant pathogenic fungi Colletotrichum musae, Colletotrichum graminicola, Colletotrichum gloeosporioides and Alternaria musae, and the ethyl acetate fraction inhibited these pathogens at rates of 85.37, 91.47, 72.77 and 89.87%, respectively (5 mg/mL)...
July 16, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28713577/seroprevalence-of-spotted-fever-group-sfg-rickettsiae-infection-in-domestic-ruminants-in-khartoum-state-sudan
#4
Nagwa M Eisawi, Dina A Hassan, Mohammed O Hussien, Azza B Musa, Abdel Rahim M El Hussein
Spotted fever group (SFG) rickettsiosis is caused by obligatory intracellular Gram-negative bacteria that belong to the genus Rickettsia. Ticks belonging to the family Ixodidae can act as vectors, reservoirs or amplifiers of SFG rickettsiae. This study was conducted to estimate the seroprevalence of SFG rickettsioses in cattle, sheep and goats from Khartoum State, Sudan. Blood samples were collected from a total of 600 animals (sheep, goats and cattle) from 32 different farms distributed in three locations in Khartoum State during the period January to December 2012...
May 2017: Veterinary Medicine and Science
https://www.readbyqxmd.com/read/28713567/genetically-engineered-bananas-resistant-to-xanthomonas-wilt-disease-and-nematodes
#5
REVIEW
Leena Tripathi, Howard Atkinson, Hugh Roderick, Jerome Kubiriba, Jaindra N Tripathi
Banana is an important staple food crop feeding more than 100 million Africans, but is subject to severe productivity constraints due to a range of pests and diseases. Banana Xanthomonas wilt caused by Xanthomonas campestris pv. musacearum is capable of entirely destroying a plantation while nematodes can cause losses up to 50% and increase susceptibility to other pests and diseases. Development of improved varieties of banana is fundamental in order to tackle these challenges. However, the sterile nature of the crop and the lack of resistance in Musa germplasm make improvement by traditional breeding techniques either impossible or extremely slow...
May 2017: Food and energy security
https://www.readbyqxmd.com/read/28707450/a-simple-concept-for-covering-pressure-sores-wound-edge-based-propeller-perforator-flap
#6
Osman Kelahmetoglu, Koenraad Van Landuyt, Caglayan Yagmur, Casper E Sommeling, Musa K Keles, Volkan Tayfur, Tekin Simsek, Yener Demirtas, Ethem Guneren
We present a new surgical modification to allow propeller perforator flaps to cover pressure sores at various locations. We used a propeller perforator flap concept based on the detection of newly formed perforator vessels located 1 cm from the wound margin and stimulated by the chronic inflammation process. Between January 2009 and January 2017, 33 wound edge-based propeller perforator flaps were used to cover pressure sores at various locations in 28 patients. In four cases more than one flap was used on the same patient...
July 13, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28706522/expressed-centromere-specific-histone-3-cenh3-variants-in-cultivated-triploid-and-wild-diploid-bananas-musa-spp
#7
Kariuki S Muiruri, Anne Britt, Nelson O Amugune, Edward K Nguu, Simon Chan, Leena Tripathi
Centromeres are specified by a centromere specific histone 3 (CENH3) protein, which exists in a complex environment, interacting with conserved proteins and rapidly evolving satellite DNA sequences. The interactions may become more challenging if multiple CENH3 versions are introduced into the zygote as this can affect post-zygotic mitosis and ultimately sexual reproduction. Here, we characterize CENH3 variant transcripts expressed in cultivated triploid and wild diploid progenitor bananas. We describe both splice- and allelic-[Single Nucleotide Polymorphisms (SNP)] variants and their effects on the predicted secondary structures of protein...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28706224/postglacial-range-expansion-and-the-role-of-ecological-factors-in-driving-adaptive-evolution-of-musa-basjoo-var-formosana
#8
Jui-Hung Chen, Chun-Lin Huang, Yu-Long Lai, Chung-Te Chang, Pei-Chun Liao, Shih-Ying Hwang, Chih-Wen Sun
Genetic variation evolves during postglacial range expansion of a species and is important for adapting to varied environmental conditions. It is crucial for the future survival of a species. We investigate the nuclear DNA sequence variation to provide evidence of postglacial range expansion of Musa basjoo var. formosana, a wild banana species, and test for adaptive evolution of amplified fragment length polymorphic (AFLP) loci underlying local adaptation in association with environmental variables. Postglacial range expansion was suggested by phylogeographical analyses based on sequence variation of the second intron of copper zinc superoxide dismutase 2 gene...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28704298/titanium-mesh-cage-as-an-alternative-reconstruction-method-for-epiphyseal-sparing-tumour-resections-in-children
#9
Mehmet Ayvaz, Senol Bekmez, Altug Yucekul, Musa U Mermerkaya, A Mazhar Tokgozoglu
In this study, we introduced an alternative reconstruction option for epiphysis-sparing tumour resection in children. Eight patients with a malignant tumour in the diaphysis or metaphysis-diaphysis junction of a long bone underwent epiphysis-sparing intercalary resection. Reconstruction was performed using a titanium mesh cage filled with impacted cancellous bone allograft and autograft. A plate and screws were used to supplement the fixation. At the last follow-up, union was achieved in seven patients. Limb-length discrepancy occurred in three patients...
July 12, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28694225/dynamic-arterial-elastance-obtained-using-arterial-signal-does-not-predict-an-increase-in-arterial-pressure-after-a-volume-expansion-in-the-operating-room
#10
Romain Lanchon, Karine Nouette-Gaulain, Laurent Stecken, Musa Sesay, Jean-Yves Lefrant, Matthieu Biais
INTRODUCTION: Dynamic arterial elastance (Eadyn) is defined as the ratio between pulse pressure variations (PPV) and stroke volume variations (SVV). Eadyn has been proposed to predict an increase in mean arterial pressure (MAP) after volume expansion with conflicting results. The aim of the present study was to test the reliability of Eadyn in hypotensive patients (MAP<65mmHg) in the operating room (OR). PATIENTS AND METHODS: The study pooled data from 51 patients...
July 7, 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/28692549/a-case-of-familial-hemophagocytic-lymphohistiocytosis-type-4-with-involvement-of-the-central-nervous-system-complicated-with-infarct
#11
Saliha Ciraci, Alper Ozcan, Mustafa M Ozdemir, Samuel C C Chiang, Bianca Tesi, Akif M Ozdemir, Musa Karakukcu, Turkan Patiroglu, Can Acipayam, Selim Doganay, Hakan Gumus, Ekrem Unal
BACKGROUND: Familial hemophagocytic lymphohistiocytosis (HLH) is a fatal disease affecting infants and very young children. Central nervous system involvement of HLH can cause catastrophic results. METHOD: We present a case with cranial involvement of familial HLH type 4 who showed diffuse infiltration of white matter complicated with intracranial thrombosis. A 5-year-old girl from a consanguineous couple presented with fever and pancytopenia, and was referred to our hematology unit...
July 7, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28688190/improvement-of-glycemic-state-among-responders-to-sofosbuvir-based-treatment-regimens-single-center-experience
#12
Shereen Abdel Alem, Aisha Elsharkawy, Rabab Fouad, Eman Adel, Zeinab Abdellatif, Sherief Musa, Ahmed Nagy, Muhammad S Hussein, Ayman Yosry, Gamal Esmat
BACKGROUND: Chronic HCV infection has emerged as a complex multifaceted disease with manifestations extending beyond the liver. HCV plays a direct role in glucose metabolism leading to both insulin resistance and type 2 diabetes. AIMS: To evaluate the changes in the glycemic state following Sofosbuvir-based treatment regimens in diabetic HCV patients. METHODS: Four hundred chronic hepatitis C patients who underwent Sofosbuvir-based treatment regimens were retrospectively screened...
July 8, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28687714/lnc-ing-inflammation-to-disease
#13
REVIEW
Loretta Magagula, Maria Gagliardi, Jerolen Naidoo, Musa Mhlanga
Termed 'master gene regulators' long ncRNAs (lncRNAs) have emerged as the true vanguard of the 'noncoding revolution'. Functioning at a molecular level, in most if not all cellular processes, lncRNAs exert their effects systemically. Thus, it is not surprising that lncRNAs have emerged as important players in human pathophysiology. As our body's first line of defense upon infection or injury, inflammation has been implicated in the etiology of several human diseases. At the center of the acute inflammatory response, as well as several pathologies, is the pleiotropic transcription factor NF-κβ...
July 7, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/28677256/xanthomonas-campestris-pv-musacearum-a-major-constraint-to-banana-plantain-and-enset-production-in-central-and-east-africa-over-the-past-decade
#14
Valentine Nakato, George Mahuku, Teresa Coutinho
Taxonomy: Bacteria; Phylum Proteobacteria; Class Gammaproteobacteria; Order Xanthomonadales; Family Xanthomonadaceae; Genus Xanthomonas; currently classified as X. campestris pv. musacearum (Xcm). However, fatty acid methyl esters analysis, genetic and genomic evidence suggest that this pathogen is X. vasicola and resides in a separate pathovar. Isolation and detection: Xcm can be isolated on Yeast Peptone Glucose Agar (YPGA), Cellobiose Cephalexin Agar and Yeast Tryptone Sucrose Agar (YTSA) complemented with 5-flouro-uracil, cephalexin and cycloheximide to confer semi-selectivity...
July 5, 2017: Molecular Plant Pathology
https://www.readbyqxmd.com/read/28674085/acute-infarct-extracellular-volume-mapping-to-quantify-myocardial-area-at-risk-and-chronic-infarct-size-on-cardiovascular-magnetic-resonance-imaging
#15
Pankaj Garg, David A Broadbent, Peter P Swoboda, James R J Foley, Graham J Fent, Tarique A Musa, David P Ripley, Bara Erhayiem, Laura E Dobson, Adam K McDiarmid, Philip Haaf, Ananth Kidambi, Rob J van der Geest, John P Greenwood, Sven Plein
BACKGROUND: Late gadolinium enhancement (LGE) imaging overestimates acute infarct size. The main aim of this study was to investigate whether acute extracellular volume (ECV) maps can reliably quantify myocardial area at risk (AAR) and final infarct size (IS). METHODS AND RESULTS: Fifty patients underwent cardiovascular magnetic resonance imaging acutely (24-72 hours) and at convalescence (3 months). The cardiovascular magnetic resonance protocol included cines, T2-weighted imaging, native T1 maps, 15-minute post-contrast T1 maps, and LGE...
July 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28672275/genetic-divergence-of-influenza-a-h3n2-amino-acid-substitutions-mark-the-beginning-of-the-2016-2017-winter-season-in-israel
#16
Aharona Glatman-Freedman, Yaron Drori, Sharon Alexandra Beni, Nehemya Friedman, Rakefet Pando, Hanna Sefty, Ilana Tal, John McCauley, Galia Rahav, Nathan Keller, Tamy Shohat, Ella Mendelson, Musa Hindiyeh, Michal Mandelboim
BACKGROUND: Influenza vaccine composition is reevaluated each year due to the frequency and accumulation of genetic changes that influenza viruses undergo. The beginning of the 2016-2017 influenza surveillance period in Israel has been marked by the dominance of influenza A(H3N2). OBJECTIVES: To evaluate the type, subtype, genetic evolution and amino acid substitutions of influenza A(H3N2) viruses detected among community patients with influenza-like illness (ILI) and hospitalized patients with respiratory illness in the first weeks of the 2016-2017 influenza season...
June 4, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28665023/physiological-molecular-and-ultrastructural-analyses-during-ripening-and-over-ripening-of-banana-musa-spp-aaa-group-cavendish-subgroup-fruit-suggest-characteristics-of-programmed-cell-death
#17
Maricruz Ramírez-Sánchez, Donald J Huber, C Eduardo Vallejos, Karen Kelley
BACKGROUND: Programmed cell death (PCD) is a part of plant development that has been studied for petal senescence and vegetative tissue but has not been thoroughly investigated for fleshy fruits. The purpose of this research was to examine ripening and over-ripening in banana fruit to determine if there were processes in common to previously described PCD. RESULTS: Loss of cellular integrity (over 40 %) and development of senescence related dark spot (SRDS) occurred after day 8 in banana peel...
June 30, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28664967/two-coexisting-liquid-phases-in-switchable-ionic-liquids
#18
Juan Yao, David B Lao, Xiao Sui, Yufan Zhou, Satish K Nune, Xiang Ma, Tyler P Troy, Musa Ahmed, Zihua Zhu, David J Heldebrant, Xiao-Ying Yu
Switchable ionic liquids (SWILs) derived from organic bases and alcohols are attractive due to their applications in gas capture, separations, and nanomaterial synthesis. However, their exact solvent structure still remains a mystery. We present the first chemical mapping of a SWIL solvent structure using in situ time-of-flight secondary ion mass spectrometry. In situ chemical mapping discovers two coexisting liquid phases and molecular structures vastly different from conventional ionic liquids. SWIL chemical speciation is found to be more complex than the known stoichiometry...
June 30, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28661315/new-onset-diabetes-after-transplant-in-a-sudanese-renal-transplant-population-prevalence-and-risk-factors
#19
Ihab Abdel-Rahim Mohamed Ahmed, Rafaa K H Osman, Nazik O Khalifa, Manal Omar Ismail, Tayeb A Musa
OBJECTIVES: New-onset diabetes after transplant is a well-recognized complication of solid-organ transplant. The true incidence of this complication in Sudan is not known. The aim of this study was to define the prevalence of new-onset diabetes after transplant in a Sudanese renal transplant population and to identify the contributing risk factors. MATERIALS AND METHODS: Fifty-nine patients who underwent living-donor related kidney transplant and who were followed for 2 years were included in this pilot study...
June 28, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28658387/first-record-of-crypticerya-zeteki-cockerell-1914-monophlebidae-in-brazil-and-maconellicoccus-hirsutus-green-1908-pseudococcidae-in-the-state-of-maranh%C3%A3-o
#20
A S J C Ramos, A L B G Peronti, T Kondo, R N S Lemos
Crypticerya zeteki (Cockerell, 1914) (Hemiptera: Coccomorpha: Monophlebidae) is recorded for the first time from Brazil and Maconellicoccus hirsutus (Green, 1908) (Hemiptera: Coccomorpha: Pseudococcidae) is recorded for the first time from the state of Maranhão, Brazil. Both species were collected from branches, leaves and fruits of various fruit trees in the municipalities of São José de Ribamar, São Luís and Paço do Lumiar, Maranhão, Brazil. Crypticerya zeteki was collected on Citrus spp. (Rutaceae), Cocos nucifera (L...
June 26, 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
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