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https://www.readbyqxmd.com/read/28817493/dna-methylation-of-the-glucocorticoid-receptor-gene-promoter-in-the-placenta-is-associated-with-blood-pressure-regulation-in-human-pregnancy
#1
Sulistyo E Dwi Putra, Christoph Reichetzeder, Martin Meixner, Karsten Liere, Torsten Slowinski, Berthold Hocher
BACKGROUND: Blood pressure (BP) regulation during pregnancy is influenced by hormones of placental origin. It was shown that the glucocorticoid system is altered in hypertensive pregnancy disorders such as preeclampsia. Epigenetic mechanism might influence the activity of genes involved in placental hormone/hormone receptor synthesis/action during pregnancy. METHOD: In the current study, we analyzed the association of 5'-C-phosphate-G-3' (CpG) site methylation of different glucocorticoid receptor gene (NR3C1) promoter regions with BP during pregnancy...
August 16, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28814313/a-mixed-methods-study-of-hiv-related-services-in-buprenorphine-treatment
#2
Hannah K Knudsen, Jennifer Cook, Michelle R Lofwall, Sharon L Walsh, Jamie L Studts, Jennifer R Havens
BACKGROUND: Opioid use disorder (OUD) is a major risk factor in the acquisition and transmission of HIV. Clinical practice guidelines call for the integration of HIV services in OUD treatment. This mixed methods study describes the integration of HIV services in buprenorphine treatment and examines whether HIV services vary by prescribers' medical specialty and across practice settings. METHODS: Data were obtained via qualitative interviews with buprenorphine experts (n = 21) and mailed surveys from US buprenorphine prescribers (n = 1174)...
August 16, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/28813097/avian-communities-in-the-amazonian-cangas-vegetation-biogeographic-affinities-components-of-beta-diversity-and-conservation
#3
Sérgio H Borges, Marcos P D Santos, Leonardo M S Soares, Antonita S DA Silva
The Amazonian cangas is a vegetation type distributed as patches of open vegetation embedded in a matrix of tropical forest and that grows over iron-rich soils in the Serra dos Carajás region. To characterize cangas avifauna, we surveyed birds in eight patches varying from 43 to 1,366 hectares. Cangas avifauna has compositional affinities with savannas widespread throughout the Amazon and other biomes, and we estimate that more than 200 bird species occurs in this habitat. Species composition was relatively homogeneous, and the similarity among cangas patches was the dominant component of the beta-diversity...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28811652/sources-of-variability-in-childhood-obesity-indicators-and-related-behaviors
#4
P T Katzmarzyk, S T Broyles, J-P Chaput, M Fogelholm, G Hu, E V Lambert, C Maher, J Maia, T Olds, V Onywera, O L Sarmiento, M Standage, M S Tremblay, C Tudor-Locke
The purpose of this study was to describe sources of variability in obesity-related variables in 6022 children aged 9-11 y from 12 countries. The study design involved recruitment of students, nested within schools, which were nested within study sites. Height, weight and waist circumference (WC) were measured and BMI was calculated; sleep duration and total and in-school moderate-to-vigorous physical activity (MVPA) and sedentary time were measured by accelerometry; and diet scores were obtained by questionnaire...
August 16, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28810071/understanding-the-geometry-of-connected-fracture-flow-with-multiperiod-oscillatory-hydraulic-tests
#5
Claire Sayler, Michael Cardiff, Michael D Fort
An understanding of the spatial and hydraulic properties of fast preferential flow pathways in the subsurface is necessary in applications ranging from contaminant fate and transport modeling to design of energy extraction systems. One method for the characterization of fracture properties over interwellbore scales is Multiperiod Oscillatory Hydraulic (MOH) testing, in which the aquifer response to oscillatory pressure stimulations is observed. MOH tests were conducted on isolated intervals of wells in siliciclastic and carbonate aquifers in southern Wisconsin...
August 15, 2017: Ground Water
https://www.readbyqxmd.com/read/28801392/can-promoting-awareness-of-fetal-movements-and-focusing-interventions-reduce-fetal-mortality-a-stepped-wedge-cluster-randomised-trial-affirm
#6
Alexander E P Heazell, Christopher J Weir, Sarah J E Stock, Catherine J Calderwood, Sarah Cunningham Burley, J Frederik Froen, Michael Geary, Alyson Hunter, Fionnuala M McAuliffe, Edile Murdoch, Aryelly Rodriguez, Mary Ross-Davie, Janet Scott, Sonia Whyte, Jane E Norman
BACKGROUND: In 2013, the stillbirth rate in the UK was 4.2 per 1000 live births, ranking 24th out of 49 high-income countries, with an annual rate of reduction of only 1.4% per year. The majority of stillbirths occur in normally formed infants, with (retrospective) evidence of placental insufficiency the most common clinical finding. Maternal perception of reduced fetal movements (RFM) is associated with placental insufficiency and increased risk of subsequent stillbirth.This study will test the hypothesis that the introduction of a package of care to increase women's awareness of the need for prompt reporting of RFM and standardised management to identify fetal compromise with timely delivery in confirmed cases, will reduce the rate of stillbirth...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28800308/cancer-stem-cells-as-functional-biomarkers
#7
Vito D'Andrea, Alessandra Panarese, Maya Tonda, Marco Biffoni, Massimo Monti
According to the American Association of Cancer Research (AACR), a Cancer Stem Cell is a cell within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that constitutes the tumor [1]. Cancer Stem Cells (CSCs) are involved in the metastatic process, in the resistance to therapeutic treatments of many types of human cancers and consequently in the onset of recurrences. Numerous translational studies have been conducted to understand CSC characteristics and evaluate association between CSC-related biomarkers and clinical outcomes...
July 31, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28799029/detecting-the-qtl-allele-system-conferring-flowering-date-in-a-nested-association-mapping-population-of-soybean-using-a-novel-procedure
#8
Shuguang Li, Yongce Cao, Jianbo He, Tuanjie Zhao, Junyi Gai
The RTM-GWAS was chosen among five procedures to identify DTF QTL-allele constitution in a soybean NAM population; 139 QTLs with 496 alleles accounting for 81.7% of phenotypic variance were detected. Flowering date (days to flowering, DTF) is an ecological trait in soybean, closely related to its ability to adapt to areas. A nested association mapping (NAM) population consisting of four RIL populations (LM, ZM, MT and MW with M8206 as their common parent) was established and tested for their DTF under five environments...
August 10, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28796846/contests-over-reproductive-resources-in-female-roller-beetles-outcome-predictors-and-sharing-as-an-option
#9
Ivette A Chamorro-Florescano, Mario E Favila, Rogelio Macías-Ordóñez
Fights among females are frequent, although less attention has been placed on them than on male fights. They arise when females compete for food, oviposition, mates, brooding sites, or access to resources which increase offspring survival. It has been shown that the outcome of female fights may be less predictable by asymmetries in resource holding power, than in male fights. Male roller beetles fight over food resources, food balls, needed for mating and nesting, and it has been show in some species that asymmetries in reproductive experience and resource holding power in terms of size predict fight outcome, including ties in which contenders cut and split the food ball...
2017: PloS One
https://www.readbyqxmd.com/read/28796448/matters-of-scale-sociology-in-and-for-a-complex-world
#10
Olli Pyyhtinen
The article proposes that if sociology is to make sense of a world that is ever more complex and complicated, it is important to reconsider the scale(s) of our relations and actions. Instead of assuming a nested vertical hierarchy of the micro to macro binary, scale should be treated not only as multiple, but also as something produced and sustained in practice. Coming to grips with the complex world, we are living in also necessitates attending to the conduits and connections between various sites, fields, and terrains to which our lives are entangled...
August 2017: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/28791134/conventional-oil-and-natural-gas-infrastructure-increases-brown-headed-cowbird-molothrus-ater-relative-abundance-and-parasitism-in-mixed-grass-prairie
#11
Jacy Bernath-Plaisted, Heather Nenninger, Nicola Koper
The rapid expansion of oil and natural gas development across the Northern Great Plains has contributed to habitat fragmentation, which may facilitate brood parasitism of ground-nesting grassland songbird nests by brown-headed cowbirds (Molothrus ater), an obligate brood parasite, through the introduction of perches and anthropogenic edges. We tested this hypothesis by measuring brown-headed cowbird relative abundance and brood parasitism rates of Savannah sparrow (Passerculus sandwichensis) nests in relation to the presence of infrastructure features and proximity to potential perches and edge habitat...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28783744/amphotis-marginata-coleoptera-nitidulidae-a-highwayman-of-the-ant-lasius-fuliginosus
#12
Bert Hölldobler, Christina L Kwapich
The space occupied by evolutionarily advanced ant societies can be subdivided into functional sites, such as broodchambers; peripheral nest chambers; kitchen middens; and foraging routes. Many predators and social parasites are specially adapted to make their living inside specific niches created by ants. In particular, the foraging paths of certain ant species are frequented by predatory and kleptoparasitic arthropods, including one striking example, the nitidulid beetle, Amphotis marginata. Adults of this species obtain the majority of their nutrition by acting as a kind of "highwayman" on the foraging trails of the ant Lasius fuliginosus, where they solicit regurgitation from food laden ant-workers by mimicking the ant's food-begging signals...
2017: PloS One
https://www.readbyqxmd.com/read/28780908/temporal-and-spatial-distribution-characteristics-in-the-natural-plague-foci-of-chinese-mongolian-gerbils-based-on-spatial-autocorrelation
#13
Hai-Wen Du, Yong Wang, Da-Fang Zhuang, Xiao-San Jiang
BACKGROUND: The nest flea index of Meriones unguiculatus is a critical indicator for the prevention and control of plague, which can be used not only to detect the spatial and temporal distributions of Meriones unguiculatus, but also to reveal its cluster rule. This research detected the temporal and spatial distribution characteristics of the plague natural foci of Mongolian gerbils by body flea index from 2005 to 2014, in order to predict plague outbreaks. METHODS: Global spatial autocorrelation was used to describe the entire spatial distribution pattern of the body flea index in the natural plague foci of typical Chinese Mongolian gerbils...
August 7, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28774269/the-association-between-bacillus-calmette-gu%C3%A3-rin-vaccination-1331-ssi-skin-reaction-and-subsequent-scar-development-in-infants
#14
Nina Marie Birk, Thomas Nørrelykke Nissen, Monica Ladekarl, Vera Zingmark, Jesper Kjærgaard, Trine Mølbæk Jensen, Signe Kjeldgaard Jensen, Lisbeth Marianne Thøstesen, Poul-Erik Kofoed, Lone Graff Stensballe, Andreas Andersen, Ole Pryds, Susanne Dam Nielsen, Christine Stabell Benn, Dorthe Lisbeth Jeppesen
BACKGROUND: The Bacillus Calmette-Guérin vaccine (BCG) against tuberculosis is administered intradermally, and vaccination is often followed by a scar at the injection site. Among BCG-vaccinated individuals, having a scar has been associated with lower mortality. We aimed to examine the impact of vaccination technique for scarring in a high income setting, by assessing the associations between the post injection reaction, the wheal size, and the probability of developing a scar, and scar size...
August 3, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28771556/common-starlings-sturnus-vulgaris-increasingly-select-for-grazed-areas-with-increasing-distance-to-nest
#15
Henning Heldbjerg, Anthony D Fox, Peder V Thellesen, Lars Dalby, Peter Sunde
The abundant and widespread Common Starling (Sturnus vulgaris) is currently declining across much of Europe due to landscape changes caused by agricultural intensification. The proximate mechanisms causing adverse effects to breeding Starlings are unclear, hampering our ability to implement cost-efficient agri-environmental schemes to restore populations to former levels. This study aimed to show how this central foraging farmland bird uses and selects land cover types in general and how use of foraging habitat changes in relation to distance from the nest...
2017: PloS One
https://www.readbyqxmd.com/read/28771368/volatile-methylsiloxanes-and-organophosphate-esters-in-the-eggs-of-european-starlings-sturnus-vulgaris-and-congeneric-gull-species-from-locations-across-canada
#16
Zhe Lu, Pamela A Martin, Neil M Burgess, Louise Champoux, John E Elliott, Enzo Baressi, Amila O De Silva, Shane de Solla, Robert J Letcher
Volatile methylsiloxanes (VMSs) and organophosphate esters (OPEs) are two suites of chemicals that are of environmental concern as organic contaminants, but little is known about the exposure of wildlife to these contaminants, particularly in birds, in terrestrial and aquatic ecosystems. The present study investigates the spatial distributions of nine cyclic and linear VMSs and seventeen OPEs in the eggs of European starlings (Sturnus vulgaris), and three congeneric gull species (i.e., herring gull (Larus argentatus), glaucous-winged gull (L...
August 3, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28770576/transformed-waldenstr%C3%A3-m-macroglobulinaemia-clinical-presentation-and-outcome-a-multi-institutional-retrospective-study-of-77-cases-from-the-french-innovative-leukemia-organization-filo
#17
Eric Durot, Cécile Tomowiak, Anne-Sophie Michallet, Jehan Dupuis, Bénédicte Hivert, Stéphane Leprêtre, Elise Toussaint, Sophie Godet, Fatiha Merabet, Eric Van Den Neste, Sarah Ivanoff, Xavier Roussel, Jean-Marc Zini, Caroline Regny, Richard Lemal, Laurent Sutton, Aurore Perrot, Katell Le Dû, Lukshe Kanagaratnam, Pierre Morel, Véronique Leblond, Alain Delmer
Histological transformation (HT) to diffuse large B-cell lymphoma (DLBCL) is a rare and poorly reported complication of Waldenström macroglobulinaemia (WM). We performed a retrospective study of 77 WM patients with biopsy-proven transformation to DLBCL. The median time from WM diagnosis to HT was 4·6 years and 16 patients (21%) had never been treated for WM. At HT, extranodal sites were observed in 91% of patients with a rather high incidence of central nervous system, cutaneous or testicular involvement...
August 2, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28767159/effects-of-in-ovo-exposure-to-3-3-4-4-tetrachlorobiphenyl-pcb-77-on-heart-development-in-tree-swallow-tachycineta-bicolor
#18
Tiffany Carro, Mary K Walker, Karen M Dean, Mary Ann Ottinger
Tree swallow (Tachycineta bicolor) eggs from two uncontaminated sites, Patuxent Research Refuge (PRR), MD and Cobleskill Reservoir, NY were dosed with PCB 77 to evaluate effects on the developing cardiovascular system. To ensure embryonic viability, treatments were administered into the air cell at embryonic day (ED) 2.5 including: untreated (control), vehicle (filtered sterilized fatty acid mixture), 100 ng/g and 1,000 ng/g egg. Eggs were dosed in the field with 0.2 μl per egg, returned to the nest, collected at ED13, hatched in the laboratory and necropsied...
August 2, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28764171/evaluation-of-hypoxia-inducible-factor-1%C3%AE-and-glucose-transporter-1-expression-in-non-melanoma-skin-cancer-an-immunohistochemical-study
#19
Iman Seleit, Ola Ahmed Bakry, Dalia Rifaat Al-Sharaky, Rania Abdel Aziz Ragab, Shimaa Ahmed Al-Shiemy
INTRODUCTION: Hypoxia Inducible Factor-1 (HIF-1) is a mediator enabling cell adaptation to hypoxia. It plays its role mainly through transcription of many target genes including Glucose Transporter-1 (GLUT-1) gene. AIM: The present work aimed at evaluating the pattern and distribution of HIF-1α and GLUT-1 in each case and control. MATERIALS AND METHODS: A case-control and retrospective study was conducted on archival blocks diagnosed from pathology department as, Basal Cell Carcinoma (BCC, 20 cases), cutaneous Squamous Cell Carcinoma (SCC, 20 cases) and 20 normal site-matched skin biopsies from age and gender-matched healthy subjects as a control...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28760787/bridging-the-age-gap-in-breast-cancer-evaluation-of-decision-support-interventions-for-older-women-with-operable-breast-cancer-protocol-for-a-cluster-randomised-controlled-trial
#20
Karen Collins, Malcolm Reed, Kate Lifford, Maria Burton, Adrian Edwards, Alistair Ring, Katherine Brain, Helena Harder, Thompson Robinson, Kwok Leung Cheung, Jenna Morgan, Riccardo Audisio, Susan Ward, Paul Richards, Charlene Martin, Tim Chater, Kirsty Pemberton, Anthony Nettleship, Christopher Murray, Stephen Walters, Oscar Bortolami, Fiona Armitage, Robert Leonard, Jacqui Gath, Deirdre Revell, Tracy Green, Lynda Wyld
INTRODUCTION: While breast cancer outcomes are improving steadily in younger women due to advances in screening and improved therapies, there has been little change in outcomes among the older age group. It is inevitable that comorbidities/frailty rates are higher, which may increase the risks of some breast cancer treatments such as surgery and chemotherapy, many older women are healthy and may benefit from their use. Adjusting treatment regimens appropriately for age/comorbidity/frailty is variable and largely non-evidence based, specifically with regard to rates of surgery for operable oestrogen receptor-positive disease and rates of chemotherapy for high-risk disease...
July 31, 2017: BMJ Open
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