keyword
MENU ▼
Read by QxMD icon Read
search

Nest site

keyword
https://www.readbyqxmd.com/read/29141345/-comparison-of-results-of-two-immunoassays-for-detection-of-hepatitis-b-surface-antigen-in-pregnant-women
#1
H Y Xiong, Y F Luo, H Y Liu, W H Han, A Q Hu, Y Wang, Y J Zheng
Objective: To evaluate and compare the detection consistency of hepatitis B surface antigen (HBsAg) by two immunoassays: enzyme-linked immunosorbent assay (ELISA) and electrochemiluminescent immunoassay (ECLIA). Methods: A prospective study was conducted among 2 296 pregnant women recruited consecutively from January 1, 2014 to January 31, 2015 in a hospital. Blood samples were collected from them for the detection of HBsAg by using ELISA and ECLIA, Kappa test was performed on the results. Nested polymerase chain reaction and sequencing of HBV S gene were also performed in all samples...
November 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29134057/a-20-year-investigation-of-declining-leatherback-hatching-success-implications-of-climate-variation
#2
Anthony R Rafferty, Christopher P Johnstone, Jeanne A Garner, Richard D Reina
Unprecedented increases in air temperature and erratic precipitation patterns are predicted throughout the twenty-first century as a result of climate change. A recent global analysis of leatherback turtle hatchling output predicts that the nesting site at Sandy Point National Wildlife Refuge (SPNWR) will experience the most significant regional climate alterations. We aimed to identify how local air temperatures and precipitation patterns influenced within-nest mortality and overall hatchling output at this site between 1990 and 2010...
October 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/29133814/structural-remodeling-and-oligomerization-of-human-cathelicidin-on-membranes-suggest-fibril-like-structures-as-active-species
#3
Enea Sancho-Vaello, Patrice François, Eve-Julie Bonetti, Hauke Lilie, Sebastian Finger, Fernando Gil-Ortiz, David Gil-Carton, Kornelius Zeth
Antimicrobial peptides as part of the mammalian innate immune system target and remove major bacterial pathogens, often through irreversible damage of their cellular membranes. To explore the mechanism by which the important cathelicidin peptide LL-37 of the human innate immune system interacts with membranes, we performed biochemical, biophysical and structural studies. The crystal structure of LL-37 displays dimers of anti-parallel helices and the formation of amphipathic surfaces. Peptide-detergent interactions introduce remodeling of this structure after occupation of defined hydrophobic sites at the dimer interface...
November 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29133316/study-protocol-for-think-a-multinational-open-label-phase-i-study-to-assess-the-safety-and-clinical-activity-of-multiple-administrations-of-nkr-2-in-patients-with-different-metastatic-tumour-types
#4
Caroline Lonez, Bikash Verma, Alain Hendlisz, Philippe Aftimos, Ahmad Awada, Eric Van Den Neste, Gaetan Catala, Jean-Pascal H Machiels, Fanny Piette, Jason B Brayer, David A Sallman, Tessa Kerre, Kunle Odunsi, Marco L Davila, David E Gilham, Frédéric F Lehmann
INTRODUCTION: NKR-2 are autologous T cells genetically modified to express a chimeric antigen receptor (CAR) comprising a fusion of the natural killer group 2D (NKG2D) receptor with the CD3ζ signalling domain, which associates with the adaptor molecule DNAX-activating protein of 10 kDa (DAP10) to provide co-stimulatory signal upon ligand binding. NKG2D binds eight different ligands expressed on the cell surface of many tumour cells and which are normally absent on non-neoplastic cells...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29126135/habitat-modification-by-the-leaf-cutter-ant-atta-cephalotes-and-patterns-of-leaf-litter-arthropod-communities
#5
Rachel L Wells, Serena K Murphy, Matthew D Moran
Ecosystem engineers are profoundly important in many biological communities. A Neotropical taxonomic group considered to have engineering effects is the Formicidae (ants). Leaf-cutter ants (LCAs), in particular, which form extensive colonies of millions of individuals, can be important ecosystem engineers in these environments. While the effects of LCAs on plant community structure and soil chemistry are well-studied, their effects on consumers are poorly understood. Therefore, we examined the indirect effects of the LCA Atta cephalotes L...
November 4, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/29124410/absence-of-haemosporidian-parasite-infections-in-the-long-lived-cory-s-shearwater-evidence-from-molecular-analyses-and-review-of-the-literature
#6
Letizia Campioni, Josué Martínez-de la Puente, Jordi Figuerola, José Pedro Granadeiro, Mónica C Silva, Paulo Catry
The apparent scarcity or absence of blood parasites in some avian groups, such as seabirds, has been related to intrinsic and extrinsic factors including host immunological capacity, host-parasite assemblage, and ecological parameters, but also to reduced sensitivity of some methods to detect low parasite prevalence/intensities of infection. Here, we examined the haemosporidian parasite prevalence in a breeding population of Cory's shearwater Calonectris diomedea borealis, a long-distance migrant seabird, nesting in the Macaronesian region, in the Eastern Atlantic...
November 9, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29121923/decentralised-training-for-medical-students-a-scoping-review
#7
Marietjie de Villiers, Susan van Schalkwyk, Julia Blitz, Ian Couper, Kalavani Moodley, Zohray Talib, Taryn Young
BACKGROUND: Increasingly, medical students are trained at sites away from the tertiary academic health centre. A growing body of literature identifies the benefits of decentralised clinical training for students, the health services and the community. A scoping review was done to identify approaches to decentralised training, how these have been implemented and what the outcomes of these approaches have been in an effort to provide a knowledge base towards developing a model for decentralised training for undergraduate medical students in lower and middle-income countries (LMICs)...
November 9, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/29120069/effects-of-exposure-to-winter-oilseed-rape-grown-from-thiamethoxam-treated-seed-on-the-red-mason-bee-osmia-bicornis
#8
Natalie Ruddle, Charlotte Elston, Olaf Klein, Anja Hamberger, Helen Thompson
There has been increasing interest on the effects of neonicotinoid insecticides on wild bees. In solitary bee species the direct link between each individual female and their reproductive success offers the opportunity to evaluate effects on individuals. The present study investigated effects of exposure to winter oilseed rape grown from thiamethoxam-treated seed on reproductive behaviour and output of solitary red mason bees (Osmia bicornis) released in 6 pairs of fields over a two-year period and confined to tunnels in a single year...
November 9, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/29118621/a-new-species-of-trachymyrmex-hymenoptera-formicidae-fungus-growing-ant-from-the-sierra-madre-oriental-of-northeastern-mexico
#9
Sergio R Sánchez-Peña, Manuela Citlali Chacón-Cardosa, Ricardo Canales-Del-Castillo, Lauren Ward, Diana Resendez-Pérez
Here we describe a new species of Trachymyrmex, T. pakawasp. n., from the Gran Sierra Plegada range of the Sierra Madre Oriental, in the states of Coahuila and Nuevo Leon, northeastern Mexico. Trachymyrmex pakawa is a large-sized species compared to other North American Trachymyrmex. Its geographic distribution includes the piedmont of the Gran Sierra Plegada at La Estanzuela, Monterrey, as well as peripheral mountains segregated from the Sierra Madre Oriental (Cerro de las Mitras, Sierra de Zapalinamé, Cañon de San Lorenzo, Cerro de las Letras)...
2017: ZooKeys
https://www.readbyqxmd.com/read/29113928/cerebral-malaria-causes-enduring-behavioral-and-molecular-changes-in-mice-brain-without-causing-gross-histopathological-damage
#10
Thaíze Lopes de Souza, Ana Claudia Beck Grauncke, Leandro Rodrigo Ribeiro, Fernanda Kulinski Mello, Sara Marchesan Oliveira, Fátima Brant, Fabiana S Machado, Mauro Schneider Oliveira
Malaria, parasitic disease considered a major health public problem, is caused by Plasmodium protozoan genus and transmitted by the bite of infected female Anopheles mosquito genus. Cerebral malaria (CM) is the most severe presentation of malaria, caused by P. falciparum and responsible for high mortality and enduring development of cognitive deficits which may persist even after cure and cessation of therapy. In the present study we evaluated selected behavioral, neurochemical and neuropathologic parameters after rescue from experimental cerebral malaria caused by P...
November 4, 2017: Neuroscience
https://www.readbyqxmd.com/read/29110405/nested-puf-proteins-extending-target-rna-elements-for-gene-regulation
#11
Kouki Shinoda, Shogo Tsuji, Shiroh Futaki, Miki Imanishi
RNA-binding proteins recognizing unique sequences within large transcriptomes serve as a powerful tool to control RNA metabolism. Pumilio and fem-3 mRNA-binding factor (PUF) proteins are considered as a good candidate for such tools because they are typically composed of eight highly homologous repeat segments and can be designed to recognize arbitrary 8-nucleotide (nt) RNA sequences. However, a specific 8-nt RNA sequence is found at multiple sites in various RNAs in the transcriptome, making it difficult to specifically target a single RNA...
November 6, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/29107954/distribution-and-identification-of-sand-flies-naturally-infected-with-leishmania-from-the-southeastern-peruvian-amazon
#12
Victor Zorrilla, Maxy B De Los Santos, Liz Espada, Rocío Del Pilar Santos, Roberto Fernandez, Albino Urquia, Craig A Stoops, Sarah-Blythe Ballard, Andres G Lescano, Gissella M Vásquez, Hugo O Valdivia
BACKGROUND: Cutaneous leishmaniasis (CL) is an important health problem in the New World affecting civilian and military populations that are frequently exposed in endemic settings. The Peruvian region of Madre de Dios located near the border with Brazil is one of the most endemic CL regions in South America with more than 4,451 reported cases between 2010 and 2015 according to the Peruvian epidemiology directorate. However, little is known regarding the diversity and distribution of sand fly vectors in this region...
November 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29103400/improving-maternal-infant-and-young-child-nutrition-in-nepal-via-peer-mobilization
#13
Akriti Singh, Rolf Dw Klemm, Gary Mundy, Pooja Pandey Rana, Bhim Pun, Kenda Cunningham
OBJECTIVE: To evaluate the impact of a peer facilitator (PF) approach for improving mothers' knowledge and practices relating to maternal and child nutrition. DESIGN: A quasi-experimental design nested within a large-scale integrated nutrition programme, Suaahara, in Nepal. Suaahara interventions were implemented in all study sites, but peer facilitators were used in only half of the study sites. SETTING: Rural, disadvantaged villages in three districts of Nepal: Bhojpur, Bajhang and Rupandehi...
November 6, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29098293/binocular-combination-of-luminance-profiles
#14
Jian Ding, Dennis M Levi
We develop and test a new two-dimensional model for binocular combination of the two eyes' luminance profiles. For first-order stimuli, the model assumes that one eye's luminance profile first goes through a luminance compressor, receives gain-control and gain-enhancement from the other eye, and then linearly combines the other eye's output profile. For second-order stimuli, rectification is added in the signal path of the model before the binocular combination site. Both the total contrast and luminance energies, weighted sums over both the space and spatial-frequency domains, were used in the interocular gain-control, while only the total contrast energy was used in the interocular gain-enhancement...
November 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/29096297/risk-assessment-and-driving-factors-for-artificial-topography-on-element-heterogeneity-case-study-at-jiangsu-china
#15
Hualong Hong, Minyue Dai, Haoliang Lu, Jingchun Liu, Jie Zhang, Chongling Yan
The rapid expansion of construction related to coastal development evokes great concern about environmental risks. Recent attention has been focused mainly on factors related to the effects of waterlogging, but there is urgent need to address the potential hazard caused by artificial topography: derived changes in the elemental composition of the sediments. To reveal possible mechanisms and to assess the environmental risks of artificial topography on transition of elemental composition in the sediment at adjoining zones, a nest-random effects-combined investigation was carried out around a semi-open seawall...
October 26, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29076535/spatial-patterns-of-fish-standing-biomass-across-brazilian-reefs
#16
R A Morais, C E L Ferreira, S R Floeter
A large fish-count dataset from the Brazilian province was used to describe spatial patterns in standing biomass and test if total biomass, taxonomic and functional trophic structure vary across nested spatial scales. Taxonomic and functional structure varied more among localities and sites than among regions. Total biomass was generally higher at oceanic islands and remote or protected localities along the coast. Lower level carnivores comprised a large part of the biomass at almost all localities (mean of 44%), zooplanktivores never attained more than 14% and omnivores were more representative of subtropical reefs and oceanic islands (up to 66% of total biomass)...
October 27, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/29074991/ants-navigation-in-an-unfamiliar-environment-is-influenced-by-their-experience-of-a-familiar-route
#17
Sebastian Schwarz, Antoine Wystrach, Ken Cheng
When displaced experimentally from a food source (feeder) to unfamiliar terrain, ants run off a portion of the homeward vector or its entirety, depending on species and conditions, and then search systematically, turning in loops of ever increasing size. The Australian desert ant Melophorus bagoti runs off a smaller portion of its vector if the test site is more dissimilar to its nest area. Here we manipulated familiarity with the training route between a feeder and the ants' nest to examine its effects when the ants were displaced to a distant site from the feeder...
October 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29071331/association-of-lipoprotein-a-with-risk-of-recurrent-ischemic-events-following-acute-coronary-syndrome-analysis-of-the-dal-outcomes-randomized-clinical-trial
#18
Gregory G Schwartz, Christie M Ballantyne, Philip J Barter, David Kallend, Lawrence A Leiter, Eran Leitersdorf, John J V McMurray, Stephen J Nicholls, Anders G Olsson, Prediman K Shah, Jean-Claude Tardif, John Kittelson
Importance: It is uncertain whether lipoprotein(a) [Lp(a)], which is associated with incident cardiovascular disease, is an independent risk factor for recurrent cardiovascular events after acute coronary syndrome (ACS). Objective: To determine the association of Lp(a) concentration measured after ACS with the subsequent risk of ischemic cardiovascular events. Design, Setting, and Participants: This nested case-cohort analysis was performed as an ad hoc analysis of the dal-Outcomes randomized clinical trial...
October 25, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29068208/well-defined-silanols-in-the-structure-of-the-calcined-high-silica-zeolite-ssz-70-new-understanding-of-a-successful-catalytic-material
#19
Stef Smeets, Zachariah J Berkson, Dan Xie, Stacey I Zones, Wei Wan, Xiaodong Zou, Ming-Feng Hsieh, Bradley F Chmelka, Lynne B McCusker, Christian Baerlocher
The structure of the calcined form of the high-silica zeolite SSZ-70 has been elucidated by combining synchrotron X-ray powder diffraction (XRPD), high resolution transmission electron microscopy (HRTEM), and two-dimensional (2D) dynamic nuclear polarization (DNP)-enhanced NMR techniques. The framework structure of SSZ-70 is a polytype of MWW and can be viewed as a disordered ABC-type stacking of MWW-layers. HRTEM and XRPD simulations show that the stacking sequence is almost random, with each layer being shifted by ±1/3 along the <110> direction with respect to the previous one...
October 25, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29066497/t-cell-localization-activation-and-clonal-expansion-in-human-pancreatic-ductal-adenocarcinoma
#20
Ingunn M Stromnes, Ayaka Hulbert, Robert H Pierce, Philip D Greenberg, Sunil R Hingorani
Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy resistant to most therapies, including immune checkpoint blockade. To elucidate mechanisms of immunotherapy resistance, we assessed immune parameters in resected human PDA. We demonstrate significant interpatient variability in T-cell number, localization, and phenotype. CD8(+) T cells, Foxp3(+) regulatory T cells, and PD-1(+) and PD-L1(+) cells were preferentially enriched in tertiary lymphoid structures that were found in most tumors compared with stroma and tumor cell nests...
November 2017: Cancer Immunology Research
keyword
keyword
108229
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"