keyword
https://read.qxmd.com/read/38312959/comparison-between-pre-covid-and-post-covid-mucormycosis-a-systematic-review-and-meta-analysis
#1
REVIEW
Dhiraj Bhambhani, Garima Bhambhani, Shaji Thomas, Suresh Bhambhani, Swapnil Parlani, Riddhi Tandon
INTRODUCTION: Mucormycosis has emerged as one of the most fatal complications arising due to COVID-19, though it has to be mentioned that the disease is capable of causing serious illness even on its own. OBJECTIVES: Through this investigation, we would review the threat that mucormycosis poses, in terms of its prevalence and degree of severity both in the pre- and post-COVID world. MATERIALS AND METHODS: A comprehensive examination of the studies published in online databases turned up 207 papers, 103 of which had undergone in-depth analysis, using both inclusion and exclusion criteria, shortlisting 15 studies that were appropriate for reviewing...
February 2024: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/38199654/prosthodontic-rehabilitation-of-patients-with-a-unilateral-subtotal-maxillectomy-using-a-customised-subperiosteal-zygomatic-implant-a-post-covid-19-mucormycosis
#2
JOURNAL ARTICLE
Ravi Marballi Basavaraju, Sujeeth Shetty, Prakash Pugazhendhi, Anupama Aradya
Restoring the maxillary resection defect involving the alveolar process, the hard and soft palate and the paranasal sinuses in terms of phonetics, mastication and deglutition is more challenging, especially with young patients with aesthetic concerns.This case report describes the prosthodontic rehabilitation of a young patient with a unilateral subtotal maxillectomy due to post-COVID-19 mucormycosis. A patient-specific subperiosteal implant was planned to rehabilitate the patient's bony defect. Using postsurgical CT, a customised subperiosteal titanium framework was fabricated by the direct metal laser sintering method using grade IV titanium alloy...
January 9, 2024: BMJ Case Reports
https://read.qxmd.com/read/38105861/a-novel-classification-system-for-oral-cavity-mucormycosis-a-hospital-based-cross-sectional-study
#3
JOURNAL ARTICLE
Kranti Bhavana, Aiswarya Vaidyanathan, Naqoosh Haidry, Bhartendu Bharti, Anil Kumar, Peeyush Shivhare
BACKGROUND: Rhino-oculo-cerebral Mucormycosis (ROCM) is a well-known complication post-COVID-19 infection. The extension of this disease into the oral cavity is a grey area with no proper protocol for management of the same in the existing literature. Based on our experience in the management of oral extension, this study aims to propose a protocol to treat these cases. AIM: To derive a classification for the surgeon from retrospectively collected data of 53 operated cases of oral Mucormycosis...
December 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/38105823/clinical-demographic-and-oral-presentations-of-covid-19%C3%A2-associated-mucormycosis-from-a-tertiary-care-hospital-in-india-a-cross-sectional-study
#4
JOURNAL ARTICLE
Surabhi Somkuwar, P Vijayabharathi, Virat Galhotra, Santhosh Rao, Nitin M Nagarkar, Manish Raghani, Vineet Kumar Pathak, Rupa Mehta
BACKGROUND: The black fungus, mucormycosis, is on the list of lethal complications reported in recent times in COVID patients. METHODOLOGY: This cross-sectional study included all cases of post-COVID-19 mucormycosis. Patients' demographics, clinical presentations, and general health information were collected using a pre-designed form. RESULTS: The study included 171 participants with the mean (SD) age as 49 (10) years with the sex distribution as 71% (122/171) male and 29% (49/122) females...
December 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/37778458/nintedanib-induced-osteomyelitis-of-the-jaw-against-the-background-of-covid-19-infection
#5
Dr Adarsh Kudva, Dr Mehul Saha, Dr G Srikanth, Dr S Arun, Dr Swati Sharma
PURPOSE: Various medications are administered to treat Coronavirus Disease 2019 (COVID-19) infection and prevent its complications. Some medicines have complications and long-term effects, which may mimic other conditions, making precise diagnosis difficult. This report aims to bring to light one such complication, medication-related osteonecrosis of the jaw (MRONJ), secondary to a commonly prescribed medication for preventing lung fibrosis post-COVID-19 infection. METHOD: A 33-year-old male reported to our department with the typical clinical and radiological features of Mucormycosis of the upper jaw post-COVID-19 infection...
September 29, 2023: Journal of Stomatology, Oral and Maxillofacial Surgery
https://read.qxmd.com/read/37661985/rhino-orbital-cerebral-mucormycosis-in-settings-of-covid-19-infection-a-case-series-of-thirteen-patients
#6
Rajesh Verma, Rajarshi Chakraborty, D B Keerthiraj, Uma S Pal
Rhino orbital cerebral mucormycosis (ROCM) is an important infectious disease encountered in large numbers in this recent post-COVID-19 era. An alteration in the defense immune system during COVID-19 illness; in the presence of uncontrolled hyperglycemia has led to the new epidemic of ROCM, especially in developing nations such as India. This case series of thirteen patients illustrates the various clinical presentations, laboratory parameters, imaging features and outcomes of patients with ROCM admitted to a tertiary care hospital in Northern India...
2023: National Journal of Maxillofacial Surgery
https://read.qxmd.com/read/37661969/clinicopathological-profile-of-post-covid-19-mucormycosis-cases-a-report-from-a-tertiary-care-center
#7
JOURNAL ARTICLE
Nupur Kaushik, Deepa Rani, Pooja Agarwal, Harendra Kumar, Lalit Kumar, Akhil Pratap Singh
INTRODUCTION: Mucormycosis is a fatal fungal infection, which is rare but commonly affects immunocompromised patients. Coronavirus disease 2019 (COVID-19) patients who were immunocompromised, due to comorbid conditions, such as hematological malignancy and diabetes mellitus (DM), and patients on immunosuppressive therapy such as steroid therapy were the important host for mucormycosis infection. AIM: This study aimed to study the clinicopathological correlation of mucormycosis in post-COVID-19 patients...
2023: National Journal of Maxillofacial Surgery
https://read.qxmd.com/read/37648209/maxillary-mucormycosis-and-aspergillosis-in-post-covid-19-patients-in-mexico-a-case-series
#8
Cynthia M Urias-Barreras, Alberto Rodríguez-Archilla, Adrian Canizalez-Roman, Daniela Bastidas, Nidia M León-Sicairos
BACKGROUND: Fungal infections, during or as a consequence of SARS-CoV-2 infection, associated with uncontrolled diabetes mellitus and indiscriminate use of corticosteroids have been reported. In the jaw, mostly mucormycosis has been diagnosed in hospitals. METHODS: A retrospective, cross-sectional, descriptive study of the clinical, imaging, and histopathologic characteristics of maxillary invasive fungal infection in post-COVID-19 patients diagnosed in a private non-hospital oral pathology service in Mexico during 2020-2022 was conducted...
August 28, 2023: Journal of Stomatology, Oral and Maxillofacial Surgery
https://read.qxmd.com/read/37550130/local-injection-of-amphotericin-b-novel-use-in-the-treatment-of-fungal-maxillary-sinusitis
#9
V Agarwal, K Kumia, A Gupta, V Singh
This report highlights the role of local amphotericin B (AMB) injection in cases of maxillary mucormycosis. The COVID-19 pandemic has resulted in a dramatic rise in the number of rhino-orbital mucormycosis cases. Although extensive surgical debridement remains the gold standard treatment, tissue salvage is desirable. The cases of two patients treated with local AMB are reported here, indicating that early intervention for maxillary fungal sinusitis in the form of local AMB may avoid the need for more invasive treatment...
August 5, 2023: International Journal of Oral and Maxillofacial Surgery
https://read.qxmd.com/read/37534351/analysis-of-the-effectiveness-of-3d-printed-patient-specific-implants-for-reconstruction-of-maxillary-defect-secondary-to-mucormycosis
#10
JOURNAL ARTICLE
Aditya Mohan Alwala, K Ramesh, Himaja Swayampakula, Nanda Gopal Vura, Sheraz Bar Shaik, K Vidya Hiranmayi
INTRODUCTION: Patients affected with mucormycosis of maxilla have been increasing following Covid-19 infections. We followed the reconstruction of the maxilla using 3D manufactured patient-specific implants. The additive manufacturing technology is capable of fabricating custom-made titanium implants precisely for oral and maxillofacial reconstructions. AIM: To analyse the effectiveness of 3D manufactured patient-specific implants in the reconstruction of maxilla affected by mucormycosis secondary to Covid-19...
September 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/37534346/comparison-of-two-types-of-patient-specific-implants-psi-and-quad-zygoma-implant-qzi-for-rehabilitation-of-post-covid-maxillary-mucormycosis-defect-pcmmd-finite-element-analysis
#11
JOURNAL ARTICLE
Varsha Sunil Manekar, Abhay N Datarkar, Ashlesha Ghormode, Surendra Daware, Prashant Pandilwar, Pranav Sapkal
INTRODUCTION: The residual post-COVID maxillary mucormycosis defect (PCMMD) were extensive, due to unilateral or bilateral maxillectomies. The Goal of rehabilitation of PCMMD is to deliver a prosthetically driven reconstruction. FEA was to evaluate the biomechanical response of PSI struts (PSI 1), PSI Screw retained (PSI 2) and QZI to masticatory load on virtual simulation to improve accuracy and enhance the design. AIM: To validate and compare the Biomechanical benefit of the PSI struts, PSI Screw retained, QZI in a case of rehabilitation of post-COVID maxillary mucormycosis defect (PCMMD) by FEA study...
September 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/37362879/stress-distribution-of-the-zygomatic-implants-in-post-mucormycosis-case-a-finite-element-analysis
#12
JOURNAL ARTICLE
Drusti K Rathod, Chitra Chakravarthy, Sri Sujan Suryadevara, Ravi S Patil, Shivaraj S Wagdargi
AIM: The aim of this study was to assess the stress distribution of the zygomatic implants in maxillectomy cases and to understand the long-term prognosis of this rehabilitation option using finite element analysis. MATERIALS AND METHODS: A three-dimensional finite element model was designed using computed tomography of a patient who underwent maxillectomy post-mucormycosis. Zygomatic implants and abutments were designed based on the manufacturer's design. Quad zygomatic implants were placed in the canine and premolar region into the zygomatic bone bilaterally...
April 9, 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/37362876/correlation-of-mucormycosis-with-various-clinical-parameters-among-covid-19-patients-a-cross-sectional-study
#13
JOURNAL ARTICLE
Harish Jadhav, Prashanth Vishwakarma, Snehal Thamke, Shruti Pundkar, Trupti Takle, Mahesh Khairnar
INTRODUCTION: Coronavirus disease 2019 (COVID-19), during the second wave in early 2021, caused devastating chaos in India. As daily infection rates continue to rise alarmingly, the number of severe cases also increased dramatically. Mucormycosis is an infection caused by filamentous molds, and there was a rise in mucormycosis cases after COVID-19 infection. The aim of the study is to assess various parameters associated with mucormycosis patients who suffered from COVID-19. MATERIAL AND METHODOLOGY: This study was a cross-sectional questionnaire study...
May 16, 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/37362874/various-treatment-modalities-in-covid-19-associated-facial-mucormycosis-and-the-need-for-its-surgical-management-a-systematic-review
#14
REVIEW
Shivya Chopra, Sneha Setiya, Pushkar P Waknis, Luke Kale, Sanika Tidke
INTRODUCTION: Mucormycosis emerged as a wildfire in post-covid-19 infected patients. Most frequently involved sites of mucormycosis are rhino-orbital, rhino-sinusal and rhino-orbito-cerebral. The hallmark sign of mucormycosis is tissue necrosis, which is often a late sign. The fatality rate of mucormycosis is 46% globally. Despite early aggressive combined surgical and medical therapy, the prognosis of mucormycosis is poor. METHODS: We searched the electronic database of PubMed, web of science, Embase, Scopus and Google Scholar from Jan 2020 until December 2021 using keywords...
March 13, 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/37362873/stress-trajectory-variations-during-occlusal-loading-in-human-skull-with-a-maxillofacial-defect-a-finite-element-analysis
#15
JOURNAL ARTICLE
Pandurangan Harikrishnan, Varadaraju Magesh
BACKGROUND AND AIM: Biting forces from the teeth are distributed to the facial bones and to the skull through the stress trajectories. The presence of a bony defect in either the maxilla or mandible might lead to variations in the stress distribution. The aim of this study was to evaluate the stress distribution and variations in stress trajectories from biting forces in a human skull with maxillofacial defect using a finite element (FE) model. METHODOLOGY: In this study, a cone beam computed tomography (CBCT) of an adult male patient with a maxillectomy defect consequent to surgical treatment of mucormycosis is evaluated for the stress distribution from the biting forces of the remaining posterior teeth...
April 22, 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/37362872/simplified-zygomatic-implant-perforated-zip-flap-for-rehabilitation-in-low-level-maxillary-defects
#16
JOURNAL ARTICLE
Swathi Iyengar Singh, Anjan Kumar Shah, Manish Kumar Singh, Nithin Kumar Sonnahalli
Rehabilitation in Low level maxillectomy cases has plethora of options right from local flaps to microvascular flaps. Subsequent to flap surgery, a maxillary dental rehabilitation can be demanding and a fixed or removable prosthesis is obligatory to provide them with near-normal function and aesthetics. Unlike the original ZIP flaps which were dedicated to microvascular flaps, we present here our unique experience with ZIP-Temporalis flap specifically for rehabilitation for patients of CAM (covid associated mucormycosis), its methods, advantages and limitations...
May 27, 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/37274089/evaluation-of-risk-factors-clinico-radiographic-presentations-of-covid-associated-mucormycosis-in-the-maxillofacial-region-reporting-to-a-tertiary-care-dental-facility
#17
JOURNAL ARTICLE
Varsha Agarwal, Ambika Gupta, Virendra Singh, Komal Kumia, Bhawna Saini, N Suriya
PURPOSE: To evaluate the prevalence of risk factors associated with COVID-associated mucormycosis (CAM) in the maxillofacial region with emphasis on clinical and radiological characteristics of the disease reporting to the dentists. METHODS: Archival records of the patients diagnosed with rhino-cerebral mucormycosis through histopathology or culture, were screened and 266 records were included. These records were divided into three groups-previously diabetic (PD, n = 122), recently diagnosed diabetic (RD, n = 105) and non-diabetic (ND, n = 39)...
2023: Journal of Oral Biology and Craniofacial Research
https://read.qxmd.com/read/37234332/studying-the-use-of-a-proposed-three-level-grossing-protocol-in-the-histopathological-diagnosis-of-covid-19-associated-rhinomaxillary-mucormycosis
#18
JOURNAL ARTICLE
Krishna Sireesha Sundaragiri, Shikha Saxena, Bharat Sankhla, Akshay Bhargava, Geeta Sharma, Isha Gaurav
INTRODUCTION: Mucormycosis is an acute and rapidly progressing opportunistic fungal infection. COVID-19-associated mucormycosis (CAM) had re-emerged as a complication of COVID-19 infection during the second wave of the pandemic in 2021. The rhinomaxillary form is a variant of the rhino-cerebral mucormycosis that presents a diagnostic challenge to the dentist and the oral and maxillofacial pathologist. Gross examination of pathological specimens is the most undermined step even though it plays a vital role in the final diagnosis...
2023: Journal of Oral and Maxillofacial Pathology: JOMFP
https://read.qxmd.com/read/37234326/inhibitory-effect-of-garlic-and-omam-extracts-on-mucor-circinelloides-a-fungus-causing-mucormycosis-an-in-vitro-study
#19
JOURNAL ARTICLE
G Nimoshini, Priyadharsini Nataraj, Annasamy Rameshkumar, Rajkumar Krishnan, S Savithri
CONTEXT: Mucor circinelloides is reported to be the second among the most common causative agents of emerging mucormycosis. It is intrinsically resistant to most known antifungals. Further the use of antifungals cause side effects. Traditional knowledge system for treating various ailments is stronger in India and it also backs deriving various bioactive compounds from herbal sources, in the modern system of medicine. Therefore, two most commonly used culinary herbal materials viz., ginger and omam were studied in vitro against M...
2023: Journal of Oral and Maxillofacial Pathology: JOMFP
https://read.qxmd.com/read/37193535/covid-related-mucormycosis-mimicking-dental-infection
#20
Saja A Alramadhan, Sumita S Sam, Shaun Young, Donald M Cohen, Mohammed N Islam, Indraneel Bhattacharyya
A recent increase in the prevalence of mucormycosis of the head and neck in patients who have recovered from COVID-19 following hospitalization has been reported. A Majority of the cases have been reported from India. Conditions such as diabetes mellitus, use of corticosteroids for other autoimmune conditions, organ transplant, immunosuppression, immunodeficiency, and malignancies especially hematologic ones, are all known risk factors for mucormycosis. Recently, hospitalization for COVID-19 has been added to the list of risk factors for opportunistic mucormycosis infection...
June 2023: Oral and maxillofacial surgery cases
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